[ { "uniprot_canonical_ac": "Q9W440-1", "uniprot_id": [ { "id": "THEM6_DROME", "url": "https://www.uniprot.org/uniprot/Q9W440", "type": "external" } ], "mass": 22956.0, "length": 193, "protein_name": "Protein THEM6", "gene_name": "Dmel\\CG4666", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001284923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284923", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG4666; CG4666; Dmel_CG4666", "gene_names_refseq": "CG4666; Dmel\\CG4666", "protein_names_uniprotkb": "Protein THEM6", "protein_names_refseq": "CG4666-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4666)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9W440-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W4N2-1", "uniprot_id": [ { "id": "CMTR1_DROME", "url": "https://www.uniprot.org/uniprot/Q9W4N2", "type": "external" } ], "mass": 90556.0, "length": 788, "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1", "gene_name": "Cmtr1", "organism": "Fruit fly", "refseq_name": "Cap methyltransferase 1, isoform B", "refseq_ac": [ { "id": "NP_001284851", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284851", "type": "external" } ], "gene_names_uniprotkb": "Cmtr1; CG6379", "gene_names_refseq": "CG6379; CMTr1; Cmtr1; Dmel\\CG6379; dCMTR1", "protein_names_uniprotkb": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; 2.1.1.57; Cap1 2'O-ribose methyltransferase 1; MTr1", "protein_names_refseq": "CG6379-PB; Cap methyltransferase 1, isoform B; Cmtr1-PB; cap1 2'-O-MTase; cap1 2'-O-ribose methyltransferase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6379)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;17989248;32504809", "class_list": "", "function": "S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs (PubMed:32504809). Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1) (PubMed:32504809). Positively regulates the Ago2-dependent small RNA pathway, with roles in both siRNA biogenesis and RISC assembly (PubMed:32504809). Involved in facilitating conversion of pre-RISC into holo-RISC, possibly by promoting the unwinding of Ago2-bound siRNA duplexes and thus the retention of the guide strand in holo-RISC (PubMed:32504809)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A9YI61;Q8SYG1", "ec_number_list": [ { "id": "2.1.1.57", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.57", "type": "external" } ], "go_molecular_function": "GO:0004483 methyltransferase cap1 activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070922 RISC complex assembly;GO:1904582 positive regulation of intracellular mRNA localization;GO:0006397 mRNA processing;GO:0032259 methylation;GO:0006370 7-methylguanosine mRNA capping", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W4N2-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W4P5-1", "uniprot_id": [ { "id": "VA0D1_DROME", "url": "https://www.uniprot.org/uniprot/Q9W4P5", "type": "external" } ], "mass": 39852.0, "length": 350, "protein_name": "V-type proton ATPase subunit d 1", "gene_name": "VhaAC39-1", "organism": "Fruit fly", "refseq_name": "vacuolar H[+] ATPase AC39 subunit 1", "refseq_ac": [ { "id": "NP_570080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570080", "type": "external" } ], "gene_names_uniprotkb": "VhaAC39-1; CG2934; VhaAC39", "gene_names_refseq": "ATP6V0D1; CG2934; Dmel\\CG2934; V0d; VhaAC39-1; VhaAC39; Vhaac39; anon-EST:GressD5; cho; vhaAC39-1; vhaAC39", "protein_names_uniprotkb": "V-type proton ATPase subunit d 1; V-ATPase 39 kDa subunit; V-ATPase subunit d 1; Vacuolar H+ ATPase subunit AC39-1; Vacuolar proton pump subunit d 1", "protein_names_refseq": "CG2934-PA; V-ATPase V0 d subunit; VhaAC39-1-PA; chocolate; vacuolar ATPsintase subunit 1; vacuolar H[+] ATPase AC39 subunit 1; vacuolar H[+] ATPase subunit AC39-1; vacuolar H[+]-ATPase C39 subunit", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); lipodystrophy (Disease Ontology:DOID:811)", "pathway": " (dme:Dmel_CG2934); (R-DME-1222556); (R-DME-77387); (R-DME-917977); (R-DME-9639288); (R-DME-983712)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in coupling of proton transport and ATP hydrolysis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0033181 plasma membrane proton-transporting V-type ATPase complex", "go_biological_process": "GO:0007034 vacuolar transport;GO:0006879 intracellular iron ion homeostasis;GO:0036295 cellular response to increased oxygen levels;GO:0007035 vacuolar acidification;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9W4P5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W4W2-1", "uniprot_id": [ { "id": "Q9W4W2_DROME", "url": "https://www.uniprot.org/uniprot/Q9W4W2", "type": "external" } ], "mass": 117452.0, "length": 1042, "protein_name": "RNA helicase", "gene_name": "fs(1)Yb", "organism": "Fruit fly", "refseq_name": "female sterile (1) Yb", "refseq_ac": [ { "id": "NP_477494", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477494", "type": "external" } ], "gene_names_uniprotkb": "fs(1)Yb; CG2706; Dmel\\CG2706; Dmel_CG2706; EG:95B7.8; Fs(1)Yb; YB; Yb; fs(1)M104; fs(1)Y[b]; nov; yb", "gene_names_refseq": "CG2706; Dmel\\CG2706; EG:95B7.8; Fs(1)Yb; YB; Yb; fs(1)M104; fs(1)Y[b]; fs(1)Yb; nov; yb", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "CG2706-PA; female sterile (1) Yb; female sterile(1)M104; female sterile(1)Yb; fs(1)Yb-PA; no ovaries", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2706)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" }, { "id": "5.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005829 cytosol;GO:0070725 Yb body", "go_biological_process": "GO:0007281 germ cell development;GO:0048477 oogenesis;GO:0030718 germ-line stem cell population maintenance;GO:0042078 germ-line stem cell division;GO:0140990 primary piRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W4W2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W5B6-1", "uniprot_id": [ { "id": "MTU1_DROME", "url": "https://www.uniprot.org/uniprot/Q9W5B6", "type": "external" } ], "mass": 43350.0, "length": 389, "protein_name": "Mitochondrial tRNA-specific 2-thiouridylase 1", "gene_name": "CG3021", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_652639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652639", "type": "external" } ], "gene_names_uniprotkb": "CG3021", "gene_names_refseq": "CG3021; Dmel\\CG3021; EG:BACR7A4.8; E; anon-1Ed", "protein_names_uniprotkb": "Mitochondrial tRNA-specific 2-thiouridylase 1; 2.8.1.13", "protein_names_refseq": "CG3021-PA; transcription unit E; uncharacterized protein", "tax_id": 7227, "disease": "infantile liver failure syndrome (Disease Ontology:DOID:0080716); transient infantile liver failure (Disease Ontology:DOID:0080778); aminoglycoside-induced deafness (Disease Ontology:DOID:0111734); inner ear disease (Disease Ontology:DOID:2952); MERRF syndrome (Disease Ontology:DOID:310); liver disease (Disease Ontology:DOID:409)", "pathway": " (dme:Dmel_CG3021)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q960Y5", "ec_number_list": [ { "id": "2.8.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.13", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0000049 tRNA binding;GO:0061708 tRNA-5-taurinomethyluridine 2-sulfurtransferase", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9W5B6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W5P1-1", "uniprot_id": [ { "id": "MED21_DROME", "url": "https://www.uniprot.org/uniprot/Q9W5P1", "type": "external" } ], "mass": 16069.0, "length": 142, "protein_name": "Mediator of RNA polymerase II transcription subunit 21", "gene_name": "MED21", "organism": "Fruit fly", "refseq_name": "mediator complex subunit 21, isoform A", "refseq_ac": [ { "id": "NP_001015223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015223", "type": "external" } ], "gene_names_uniprotkb": "MED21; CG17397; Trap19", "gene_names_refseq": "CG17397; CG40364; Dmel\\CG17397; MED21; Med21; Trap19; dSRB7; dTRAP19; med21; p18", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 21; Mediator complex subunit 21; dMED21; dSRB7; dTRAP19", "protein_names_refseq": "CG17397-PA; MED21-PA; mediator complex subunit 21, isoform A; mediator", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17397)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11259581;12021283;12537569;12537572;15477388", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for activated transcription of the MtnA, MtnB and MtnD genes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8Y534", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9W5P1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYF4-1", "uniprot_id": [ { "id": "DRONC_DROME", "url": "https://www.uniprot.org/uniprot/Q9XYF4", "type": "external" } ], "mass": 51141.0, "length": 450, "protein_name": "Caspase Dronc", "gene_name": "Dronc", "organism": "Fruit fly", "refseq_name": "death regulator Nedd2-like caspase", "refseq_ac": [ { "id": "NP_524017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524017", "type": "external" } ], "gene_names_uniprotkb": "Dronc; CG8091; Nc", "gene_names_refseq": "CG8090; CG8091; DRONC; Dmel\\CG8091; Dronc/Casp9; Dronc; Nc\\Dronc; Nc; anon-EST:GreesD6; anon-EST:GressD6; anon-WO0118547.313; caspase-9; dronc", "protein_names_uniprotkb": "Caspase Dronc; 3.4.22.62; Death regulator NEDD2-like caspase", "protein_names_refseq": "CG8091-PA; Caspase-9-like; Dronc-PA; caspase-9; death regulator Nedd2-like caspase; dronc; drosophila Caspase-9 homologue; drosophila Nedd2-like caspase; nedd 2-like caspase", "tax_id": 7227, "disease": "stroke (Disease Ontology:DOID:0051061); autosomal recessive intellectual developmental disorder (Disease Ontology:DOID:0060308); Alzheimer's disease (Disease Ontology:DOID:10652); status epilepticus (Disease Ontology:DOID:1824); testicular cancer (Disease Ontology:DOID:2998); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (dme:Dmel_CG8091); (R-DME-6803207)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10200258;10675329;10731132;10984473;12021771;12537569;12537572;14517550;20700104;21220123;25644603;38381783", "class_list": "", "function": "Involved in the activation cascade of caspases responsible for apoptosis execution (PubMed:10200258, PubMed:10675329, PubMed:10984473). Effector of steroid-mediated apoptosis during insect metamorphosis (PubMed:10984473). Overexpression promotes programmed cell death (PubMed:10200258, PubMed:10675329, PubMed:10984473). Interaction with Diap1 is required to suppress Dronc-mediated cell death; via Diap1-mediated ubiquitination of Dronc (PubMed:10675329, PubMed:14517550). Rate-limiting caspase in rpr, grim and hid death pathway (PubMed:10984473, PubMed:14517550). Recruited to the Dark apoptosome, an adapter protein complex that mediates activation of the caspase cascade in programmed cell death initiated by the intrinsic apoptosis pathway (PubMed:21220123, PubMed:25644603). Association with the Dark apoptosome stimulates autocatalytic cleavage and activation of Dronc, promoting Dronc-mediated cleavage of downstream effector caspases such as Drice (PubMed:21220123, PubMed:25644603)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.22.61", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.61", "type": "external" }, { "id": "3.4.22.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.62", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0004197 cysteine-type endopeptidase activity;GO:0050700 CARD domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043293 apoptosome", "go_biological_process": "GO:0048749 compound eye development;GO:0008285 negative regulation of cell population proliferation;GO:0016322 neuron remodeling;GO:0006915 apoptotic process;GO:2001235 positive regulation of apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9XYF4-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYN7-1", "uniprot_id": [ { "id": "PSB3_DROME", "url": "https://www.uniprot.org/uniprot/Q9XYN7", "type": "external" } ], "mass": 23234.0, "length": 205, "protein_name": "Proteasome subunit beta type-3", "gene_name": "Prosbeta3", "organism": "Fruit fly", "refseq_name": "proteasome beta3 subunit", "refseq_ac": [ { "id": "NP_649858", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649858", "type": "external" } ], "gene_names_uniprotkb": "Prosbeta3; CG11981", "gene_names_refseq": "11981; Beta-3; CG11981; Dmel\\CG11981; Pros beta3; Prosbeta3; beta-3; beta3", "protein_names_uniprotkb": "Proteasome subunit beta type-3; 20S proteasome subunit beta-3", "protein_names_refseq": "20S proteasome beta3 subunit; 20s proteasome; CG11981-PA; Prosbeta3-PA; beta3; proteasome beta3 subunit", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG11981); (R-DME-1169091); (R-DME-1234176); (R-DME-1236974); (R-DME-1236978); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209406); (R-DME-209461); (R-DME-216167); (R-DME-2467813); (R-DME-2871837); (R-DME-350562); (R-DME-382556); (R-DME-432395); (R-DME-432524); (R-DME-432626); (R-DME-450408); (R-DME-4608870); (R-DME-4641257); (R-DME-4641258); (R-DME-5358346); (R-DME-538864); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5632684); (R-DME-5658442); (R-DME-5676590); (R-DME-5689603); (R-DME-5689880); (R-DME-68867); (R-DME-68949); (R-DME-69017); (R-DME-69601); (R-DME-75815); (R-DME-8854050); (R-DME-8939236); (R-DME-8939902); (R-DME-8941858); (R-DME-8948751); (R-DME-8951664); (R-DME-9020702); (R-DME-9755511); (R-DME-9762114); (R-DME-983168); (R-DME-9907900); (R-DME-9912633); (R-DME-9929491); (R-DME-9932298); (R-DME-9954709)", "pathway_count": 58, "publication_count": 37, "publication_id_list": "10102270;10417378;10458606;10481010;10731132;11585911;12231619;12432393;12442174;12537569;12537572;12973300;15178801;15258584;15331761;16139204;16299518;16326393;16386907;16543224;16603629;16651542;16740475;16794082;16951084;17102630;17925225;18519643;18593878;19185492;7705656;8948598;9025065;9215627;9553105;9872961;9990853", "class_list": "", "function": "Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0APH4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 3.8, "record_id": "Q9XYN7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYQ2-1", "uniprot_id": [ { "id": "UN119_DROME", "url": "https://www.uniprot.org/uniprot/Q9XYQ2", "type": "external" } ], "mass": 28412.0, "length": 265, "protein_name": "Protein unc-119 homolog", "gene_name": "unc-119", "organism": "Fruit fly", "refseq_name": "unc-119, isoform C", "refseq_ac": [ { "id": "NP_001284978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284978", "type": "external" } ], "gene_names_uniprotkb": "unc-119; CG1659", "gene_names_refseq": "CG1659; DmUNC-119; Dmel\\CG1659; Unc-119; Unc119; anon-EST:Posey123; dm unc-119; unc-119", "protein_names_uniprotkb": "Protein unc-119 homolog; DmUNC-119", "protein_names_refseq": "CG1659-PC; unc-119, isoform C; unc-119-PC", "tax_id": 7227, "disease": "cone-rod dystrophy (Disease Ontology:DOID:0050572); cone-rod dystrophy 24 (Disease Ontology:DOID:0081449); immunodeficiency 13 (Disease Ontology:DOID:0111987)", "pathway": " (dme:Dmel_CG1659)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;10858820;12537572", "class_list": "", "function": "Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005929 cilium", "go_biological_process": "GO:0007399 nervous system development;GO:0042953 lipoprotein transport;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9XYQ2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYU0-1", "uniprot_id": [ { "id": "MCM7_DROME", "url": "https://www.uniprot.org/uniprot/Q9XYU0", "type": "external" } ], "mass": 81284.0, "length": 720, "protein_name": "DNA replication licensing factor Mcm7", "gene_name": "Mcm7", "organism": "Fruit fly", "refseq_name": "minichromosome maintenance 7", "refseq_ac": [ { "id": "NP_523984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523984", "type": "external" } ], "gene_names_uniprotkb": "Mcm7; CG4978", "gene_names_refseq": "CG4978; DmMCM7; DmeMCM7; Dmel\\CG4978; MCM7; McM7; Mcm7; Mcp-PCR1; PCR1; anon-EST:Liang-1.66; clone 1.66; dMcm7; mcm7", "protein_names_uniprotkb": "DNA replication licensing factor Mcm7; 3.6.4.12; DmMCM3; Minichromosome maintenance 7 protein", "protein_names_refseq": "CG4978-PA; Mcm7-PA; minichromosome maintenance 7; minichromosome maintenance-PCR1", "tax_id": 7227, "disease": "pancreatic ductal carcinoma (Disease Ontology:DOID:3587); hepatocellular carcinoma (Disease Ontology:DOID:684); hyperthyroidism (Disease Ontology:DOID:7998)", "pathway": " (dme:Dmel_CG4978); (R-DME-176187); (R-DME-68867); (R-DME-68949); (R-DME-68962); (R-DME-69052)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "10023044;10731132;12537572;16798881;20122406;9795205", "class_list": "", "function": "Acts as a component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P91674", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" }, { "id": "5.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042555 MCM complex;GO:0071162 CMG complex", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0006260 DNA replication;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication;GO:0006279 premeiotic DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9XYU0-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYU1-1", "uniprot_id": [ { "id": "MCM3_DROME", "url": "https://www.uniprot.org/uniprot/Q9XYU1", "type": "external" } ], "mass": 90918.0, "length": 819, "protein_name": "DNA replication licensing factor Mcm3", "gene_name": "Mcm3", "organism": "Fruit fly", "refseq_name": "minichromosome maintenance 3, isoform A", "refseq_ac": [ { "id": "NP_511048", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_511048", "type": "external" } ], "gene_names_uniprotkb": "Mcm3; CG4206; DmMCM3; DmMcm3; DmeMCM3; Dmel\\CG4206; Dmel_CG4206; MCM3; McM3; Mcm3-RA; Mcp-PCR2; PCR2; dMCM3; dMcm3; mcm3; smu", "gene_names_refseq": "CG4206; DmMCM3; DmMcm3; DmeMCM3; Dmel\\CG4206; MCM3; McM3; Mcm3; Mcp-PCR2; PCR2; dMCM3; dMcm3; mcm3; smu", "protein_names_uniprotkb": "DNA replication licensing factor Mcm3; 3.6.4.12; DmMCM3; Minichromosome maintenance 3 protein", "protein_names_refseq": "CG4206-PA; Mcm3-PA; minichromosome maintenance 3, isoform A; minichromosome maintenance-PCR2; small mushroom bodies", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4206); (R-DME-176187); (R-DME-68867); (R-DME-68949); (R-DME-68962); (R-DME-69052)", "pathway_count": 6, "publication_count": 17, "publication_id_list": "10023044;10731132;12537568;12537572;12537573;12537574;16110336;16798881;17372656;17569856;17569867;18327897;20122406;25589440;26109356;26109357;9795205", "class_list": "", "function": "Acts as a component of the Mcm2-7 complex (Mcm complex) (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, PubMed, PubMed]; Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "P91675", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" }, { "id": "5.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0042555 MCM complex;GO:0071162 CMG complex;GO:0005694 chromosome", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0006260 DNA replication;GO:1902975 mitotic DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication;GO:0006279 premeiotic DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q9XYU1-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XZ56-1", "uniprot_id": [ { "id": "4EBP_DROME", "url": "https://www.uniprot.org/uniprot/Q9XZ56", "type": "external" } ], "mass": 12876.0, "length": 117, "protein_name": "Eukaryotic translation initiation factor 4E-binding protein", "gene_name": "Thor", "organism": "Fruit fly", "refseq_name": "thor, isoform B", "refseq_ac": [ { "id": "NP_001285588", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285588", "type": "external" } ], "gene_names_uniprotkb": "Thor; CG8846", "gene_names_refseq": "153432_at; 43-BP; 4E-BP1; 4E-BP; 4EBP; 4e-BP; 4e-bp; 4eBP; 4ebp; BcDNA.HL08053; BcDNA:HL08053; CG8846; CT8705; Dm 4E-BP; Dmel\\CG8846; Phas1; Thor/EIF4EBP; Thor; anon-WO0172774.158; d4E-BP1; d4E-BP; d4EBP; d4e-bp; d4eBP; dthor; eIF4E-BP; l(2)06270; l(2)k07736; l(2)k13517; p4EBP; pp20; thor", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4E-binding protein; 4E-BP; 4E-binding protein Thor; d4E-BP; dThor; eIF4E-binding protein", "protein_names_refseq": "CG8846-PB; Eif4e-binding protein; Thor-PB; eIF-4E-binding protein; eIF4E binding protein; eif-4e binding protein; eif4e-binding protein 4EBP; eukaryotic initiation factor 4E binding protein; eukaryotic initiation factor 4E- binding protein; eukaryotic initiation factor 4E-binding protein; eukaryotic translation initiation factor 4E binding protein; eukaryotic translation initiation factor 4E-binding protein; insulin-stimulated eIF-4E binding protein; lethal (2) 06270; thor, isoform B; translation initiation factor 4E binding protein", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); tuberous sclerosis (Disease Ontology:DOID:13515); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dme:Dmel_CG8846); (R-DME-110523); (R-DME-166208); (R-DME-72662)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10731132;10811906;11389445;11752451;12172554;12537569;12537572;12771962;14645523;19804760;25702871;27525480;27916456;28827349", "class_list": "", "function": "Repressor of translation initiation that regulates eIF4E1 activity by preventing its assembly into the eIF4F complex (PubMed:11389445, PubMed:19804760, PubMed:25702871). Hypophosphorylated form competes with eIF4G1 and strongly binds to eIF4E1, leading to repress translation (PubMed:25702871). In contrast, hyperphosphorylated form dissociates from eIF4E1, allowing interaction between eIF4G1 and eIF4E1, leading to initiation of translation (PubMed:25702871). Acts as a regulator of various biological processes, such as innate immunity, cell growth or synaptic transmission (PubMed:10811906, PubMed:11389445, PubMed:27525480). Acts downstream of phosphoinositide-3-kinase (PI3K) to regulate cell growth (PubMed:11389445). Extends lifespan upon dietary restriction by regulating the mitochondrial translation (PubMed:19804760). Acts as a regulator of lifespan in response to cold by regulating the mitochondrial translation (PubMed:28827349). Acts as a negative regulator of presynaptic release of neurotransmitter in motor neurons: Thor expression is induced in response to insulin signaling, leading to prevent of translation of complexin (cpx), a protein known to regulate the exocytosis of synaptic vesicles (PubMed:27525480). Acts as a negative regulator of synaptic strength at the neuromuscular junction: Thor expression in response to acute fasting prevents translation, thereby suppressing retrograde synaptic enhancement (PubMed:27916456)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008190 eukaryotic initiation factor 4E binding;GO:0030371 translation repressor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0031594 neuromuscular junction;GO:0098793 presynapse", "go_biological_process": "GO:0006641 triglyceride metabolic process;GO:0006955 immune response;GO:0006979 response to oxidative stress;GO:0019731 antibacterial humoral response;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9XZ56-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XZ63-1", "uniprot_id": [ { "id": "ARMET_DROME", "url": "https://www.uniprot.org/uniprot/Q9XZ63", "type": "external" } ], "mass": 20136.0, "length": 173, "protein_name": "Mesencephalic astrocyte-derived neurotrophic factor homolog", "gene_name": "Manf", "organism": "Fruit fly", "refseq_name": "mesencephalic astrocyte-derived neurotrophic factor", "refseq_ac": [ { "id": "NP_477445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477445", "type": "external" } ], "gene_names_uniprotkb": "Manf; ARP-like; CG7013", "gene_names_refseq": "ARP-like; CG7013; DMANF; DmMANF; DmManf; Dmel\\CG7013; MANF; Manf; anon-EST:ParkEST188; manf", "protein_names_uniprotkb": "Mesencephalic astrocyte-derived neurotrophic factor homolog; DmMANF; MANF/CDNF-like protein", "protein_names_refseq": "ARP-like; CG7013-PA; Manf-PA; mesencephalic astrocyte-derived neurotrophic factor ortholog; mesencephalic astrocyte-derived neurotrophic factor", "tax_id": 7227, "disease": "Parkinsonism (Disease Ontology:DOID:0080855); bacterial infectious disease (Disease Ontology:DOID:104); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); breast cancer (Disease Ontology:DOID:1612); squamous cell carcinoma (Disease Ontology:DOID:1749); pancreatic cancer (Disease Ontology:DOID:1793); lung non-small cell carcinoma (Disease Ontology:DOID:3908); renal cell carcinoma (Disease Ontology:DOID:4450)", "pathway": " (dme:Dmel_CG7013); (R-DME-114608)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10597048;10731132;12537569;12537572;19164766", "class_list": "", "function": "Required during the maturation of the embryonic nervous system for maintenance of neuronal and cuticular connectivity. Essential for maintenance of dopaminergic neurons and dopamine levels., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VEW4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0045202 synapse;GO:0012505 endomembrane system", "go_biological_process": "GO:0031175 neuron projection development;GO:0070050 neuron cellular homeostasis;GO:0001963 synaptic transmission, dopaminergic;GO:0042417 dopamine metabolic process;GO:0071542 dopaminergic neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9XZ63-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XZJ4-1", "uniprot_id": [ { "id": "PSA6_DROME", "url": "https://www.uniprot.org/uniprot/Q9XZJ4", "type": "external" } ], "mass": 27162.0, "length": 244, "protein_name": "Proteasome subunit alpha type-6", "gene_name": "Prosalpha1", "organism": "Fruit fly", "refseq_name": "proteasome alpha1 subunit, isoform B", "refseq_ac": [ { "id": "NP_524837", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524837", "type": "external" } ], "gene_names_uniprotkb": "Prosalpha1; CG18495; Prosalpha6", "gene_names_refseq": "18495; Alpha-1; CG18495; Dmel\\CG18495; PSA6_DROME; Pros alpha1; Prosalpha1; Prosalpha6; alpha-1; alpha1; l(2)SH2 2342; l(2)SH2342; prosalpha1; prosalpha6", "protein_names_uniprotkb": "Proteasome subunit alpha type-6; 20S proteasome subunit alpha-1", "protein_names_refseq": "20S proteasome subunit alpha1; 20s proteasome; CG18495-PB; Prosalpha1-PB; alpha-subunit of 20S proteasome; lethal (2) SH2342; proteasome alpha1 subunit, isoform B; proteasome alpha6 subunit", "tax_id": 7227, "disease": "myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG18495); (dme:Dmel_CG30382); (R-DME-1169091); (R-DME-1234176); (R-DME-1236974); (R-DME-1236978); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209406); (R-DME-209461); (R-DME-216167); (R-DME-2467813); (R-DME-2871837); (R-DME-350562); (R-DME-382556); (R-DME-432395); (R-DME-432524); (R-DME-432626); (R-DME-450408); (R-DME-4608870); (R-DME-4641257); (R-DME-4641258); (R-DME-5358346); (R-DME-538864); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5632684); (R-DME-5658442); (R-DME-5676590); (R-DME-5689603); (R-DME-5689880); (R-DME-68867); (R-DME-68949); (R-DME-69017); (R-DME-69601); (R-DME-75815); (R-DME-8854050); (R-DME-8939236); (R-DME-8939902); (R-DME-8941858); (R-DME-8948751); (R-DME-8951664); (R-DME-9020702); (R-DME-9755511); (R-DME-9762114); (R-DME-983168); (R-DME-9907900); (R-DME-9912633); (R-DME-9929491); (R-DME-9932298); (R-DME-9954709)", "pathway_count": 59, "publication_count": 36, "publication_id_list": "10102270;10417378;10458606;10481010;10731132;11585911;12231619;12432393;12442174;12537572;12973300;15178801;15258584;15331761;15952742;16139204;16299518;16326393;16386907;16543224;16603629;16651542;16740475;16794082;17102630;17925225;18519643;18593878;19185492;23622245;7705656;8948598;9025065;9215627;9553105;9990853", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E9G1;Q9V324", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "Q9XZJ4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XZS3-1", "uniprot_id": [ { "id": "TMA7_DROME", "url": "https://www.uniprot.org/uniprot/Q9XZS3", "type": "external" } ], "mass": 6868.0, "length": 64, "protein_name": "Translation machinery-associated protein 7 homolog", "gene_name": "CG13364", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_652500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652500", "type": "external" } ], "gene_names_uniprotkb": "CG13364", "gene_names_refseq": "CG13364; CG18451; Dmel\\CG13364; EG:115C2.12; anon-EST:Posey36", "protein_names_uniprotkb": "Translation machinery-associated protein 7 homolog; Coiled-coil domain-containing protein 72 homolog", "protein_names_refseq": "CG13364-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13364)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;10731137;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9XZS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Y105-1", "uniprot_id": [ { "id": "SYQ_DROME", "url": "https://www.uniprot.org/uniprot/Q9Y105", "type": "external" } ], "mass": 87508.0, "length": 778, "protein_name": "Probable glutamine--tRNA ligase", "gene_name": "GlnRS", "organism": "Fruit fly", "refseq_name": "Glutaminyl-tRNA synthetase", "refseq_ac": [ { "id": "NP_524841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524841", "type": "external" } ], "gene_names_uniprotkb": "GlnRS; Aats-gln; CG10506", "gene_names_refseq": "Aast-g1n; Aats-gln; BcDNA:GH11673; CG10506; Dmel\\CG10506; GlnRS; QRS; dQARS; l(3)05461; qars", "protein_names_uniprotkb": "Probable glutamine--tRNA ligase; 6.1.1.18; Glutaminyl-tRNA synthetase", "protein_names_refseq": "CG10506-PA; GlnRS-PA; Glutaminyl-tRNA synthetase", "tax_id": 7227, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446)", "pathway": " (dme:Dmel_CG10506); (R-DME-9856649)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;10731138;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VBU3", "ec_number_list": [ { "id": "6.1.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.10", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "6.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.4", "type": "external" }, { "id": "6.1.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.19", "type": "external" }, { "id": "6.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.6", "type": "external" }, { "id": "6.1.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.18", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004819 glutamine-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0017101 aminoacyl-tRNA synthetase multienzyme complex", "go_biological_process": "GO:0048813 dendrite morphogenesis;GO:0006425 glutaminyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9Y105-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4JCS5-1", "uniprot_id": [ { "id": "A0A0B4JCS5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4JCS5", "type": "external" } ], "mass": 31311.0, "length": 280, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "CR30082", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001188942", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188942", "type": "external" } ], "gene_names_uniprotkb": "CR30082; CG30082; Dmel\\CG30082; Dmel_CG30082; SP216", "gene_names_refseq": "CG30082; CR30082; Dmel\\CG30082; SP216", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "CG30082-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30082)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4JCS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4JCT2-1", "uniprot_id": [ { "id": "A0A0B4JCT2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4JCT2", "type": "external" } ], "mass": 33386.0, "length": 298, "protein_name": "SCP domain-containing protein", "gene_name": "Dmel\\CG17575", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001188917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188917", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG17575; CG17575; Dmel_CG17575; anon-SAGE:Wang-113", "gene_names_refseq": "CG17575; Dmel\\CG17575; anon-SAGE:Wang-113", "protein_names_uniprotkb": "SCP domain-containing protein", "protein_names_refseq": "CG17575-PB; anon-SAGE:Wang-113; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17575)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination;GO:0008104 intracellular protein localization;GO:0007618 mating;GO:0046008 regulation of female receptivity, post-mating;GO:0046692 sperm competition", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4JCT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4JCU3-1", "uniprot_id": [ { "id": "A0A0B4JCU3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "type": "external" } ], "mass": 80674.0, "length": 716, "protein_name": "Receptor expression enhancing protein A, isoform I", "gene_name": "ReepA", "organism": "Fruit fly", "refseq_name": "receptor expression enhancing protein A, isoform I", "refseq_ac": [ { "id": "NP_001188988", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188988", "type": "external" } ], "gene_names_uniprotkb": "ReepA; BcDNA:LD42159; BcDNA:RE29641; CG30190; CG30193; CG42678; CG9848; D-reep1; Dmel\\CG42678; Dmel_CG42678; REEP1; REEPA; Reep1; anon-WO0118547.113; reep1", "gene_names_refseq": "BcDNA:LD42159; BcDNA:RE29641; CG30190; CG30193; CG42678; CG9848; D-reep1; Dmel\\CG42678; REEP1; REEPA; Reep1; ReepA; anon-WO0118547.113; reep1", "protein_names_uniprotkb": "Receptor expression enhancing protein A, isoform I", "protein_names_refseq": "CG42678-PI; REEP1 homolog; REEP1 ortholog; ReepA-PI; receptor expression enhancing protein 1; receptor expression enhancing protein A, isoform I", "tax_id": 7227, "disease": "hereditary spastic paraplegia 72B (Disease Ontology:DOID:0070642); autosomal recessive distal hereditary motor neuronopathy 6 (Disease Ontology:DOID:0081425); hereditary spastic paraplegia 31 (Disease Ontology:DOID:0110782); hereditary spastic paraplegia 72A (Disease Ontology:DOID:0110817); autosomal dominant distal hereditary motor neuronopathy 12 (Disease Ontology:DOID:0111205)", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005881 cytoplasmic microtubule;GO:0098793 presynapse;GO:0071782 endoplasmic reticulum tubular network", "go_biological_process": "GO:0071786 endoplasmic reticulum tubular network organization;GO:0034976 response to endoplasmic reticulum stress;GO:0007029 endoplasmic reticulum organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4JCU3-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4JCU6-1", "uniprot_id": [ { "id": "A0A0B4JCU6_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU6", "type": "external" } ], "mass": 15726.0, "length": 139, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42697", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001188967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188967", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42697; CG42697; Dmel_CG42697", "gene_names_refseq": "CG42697; Dmel\\CG42697", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42697-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42697)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4JCU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4JD97-1", "uniprot_id": [ { "id": "A0A0B4JD97_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4JD97", "type": "external" } ], "mass": 147156.0, "length": 1322, "protein_name": "Transforming acidic coiled-coil protein, isoform K", "gene_name": "tacc", "organism": "Fruit fly", "refseq_name": "transforming acidic coiled-coil protein, isoform K", "refseq_ac": [ { "id": "NP_001189169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189169", "type": "external" } ], "gene_names_uniprotkb": "tacc; CG9765; D-TACC; D-tacc; DTACC; Dmel\\CG9765; Dmel_CG9765; TACCdm; TACC; acc; d-tacc; dTACC; dtacc", "gene_names_refseq": "CG9765; D-TACC; D-tacc; DTACC; Dmel\\CG9765; TACCdm; TACC; acc; d-tacc; dTACC; dtacc; tacc", "protein_names_uniprotkb": "Transforming acidic coiled-coil protein, isoform K", "protein_names_refseq": "CG9765-PK; D. melanogaster transforming acidic coiled coil; drosophila transforming acidic Coiled-Coil protein; drosophila transforming acidic coiled-coil; tacc-PK; transforming acidic coiled-coil protein, isoform K; transforming acidic coiled-coil", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9765)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0000235 astral microtubule;GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005876 spindle microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007143 female meiotic nuclear division;GO:0007026 negative regulation of microtubule depolymerization;GO:0008104 intracellular protein localization;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4JD97-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4JCZ0-1", "uniprot_id": [ { "id": "A0A0B4JCZ0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4JCZ0", "type": "external" } ], "mass": 108333.0, "length": 990, "protein_name": "Oxysterol-binding protein", "gene_name": "Orp8", "organism": "Fruit fly", "refseq_name": "Oxysterol-binding protein-related protein 8, isoform M", "refseq_ac": [ { "id": "NP_001189250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189250", "type": "external" } ], "gene_names_uniprotkb": "Orp8; 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CG33180; CG9126; CG9136; Dmel\\CG33180; Dmel_CG33180; RanBP16", "gene_names_refseq": "CG33180; CG9126; CG9136; Dmel\\CG33180; RanBP16; Ranbp16", "protein_names_uniprotkb": "Ran-binding protein 16", "protein_names_refseq": "CG33180-PH; Ranbp16, isoform H; Ranbp16-PH", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33180)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May function as a nuclear transport receptor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BI24;Q9VXL6;Q9VXL7", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0005049 nuclear export signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005643 nuclear pore;GO:0005737 cytoplasm", "go_biological_process": "GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9GQN0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JGZ9-1", "uniprot_id": [ { "id": "E1JGZ9_DROME", "url": "https://www.uniprot.org/uniprot/E1JGZ9", "type": "external" } ], "mass": 27162.0, "length": 244, "protein_name": "Proteasome subunit alpha type", "gene_name": "Prosalpha1R", "organism": "Fruit fly", "refseq_name": "proteasome alpha1 subunit-related, isoform B", "refseq_ac": [ { "id": "NP_001163078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163078", "type": "external" } ], "gene_names_uniprotkb": "Prosalpha1R; 30382; CG30382; Dmel\\CG30382; Dmel_CG30382; Pros-alpha1; Prosalpha6", "gene_names_refseq": "30382; CG30382; Dmel\\CG30382; Pros-alpha1; Prosalpha1R; Prosalpha6", "protein_names_uniprotkb": "Proteasome subunit alpha type", "protein_names_refseq": "CG30382-PB; Prosalpha1R-PB; alpha-subunit of 20S proteasome; proteasome alpha1 subunit-related, isoform B; proteasome alpha1 subunit", "tax_id": 7227, "disease": "myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG18495); (dme:Dmel_CG30382)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E1JGZ9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KFS5-1", "uniprot_id": [ { "id": "A0A0B4KFS5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KFS5", "type": "external" } ], "mass": 113336.0, "length": 991, "protein_name": "1.14.11.16; Aspartyl beta-hydroxylase, isoform L", "gene_name": "Asph", "organism": "Fruit fly", "refseq_name": "aspartyl beta-hydroxylase, isoform L", "refseq_ac": [ { "id": "NP_001261020", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261020", "type": "external" } ], "gene_names_uniprotkb": "Asph; CG18658; CG8421; Dmel\\CG8421; Dmel_CG8421; humbug", "gene_names_refseq": "Asph; BAH/humbug; CG18658; CG8421; Dmel\\CG8421", "protein_names_uniprotkb": "1.14.11.16; Aspartyl beta-hydroxylase, isoform L", "protein_names_refseq": "Asph-PL; CG8421-PL; aspartyl beta-hydroxylase, isoform L", "tax_id": 7227, "disease": "chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515); cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (dme:Dmel_CG8421)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 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"ec_number_list": [], "go_molecular_function": "GO:0062101 peptidyl-aspartic acid 3-dioxygenase activity", "go_cellular_component": "GO:0012505 endomembrane system;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0051480 regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFS5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B7YZK5-1", "uniprot_id": [ { "id": "B7YZK5_DROME", "url": "https://www.uniprot.org/uniprot/B7YZK5", "type": "external" } ], "mass": 62653.0, "length": 560, "protein_name": "Jabba, isoform C", "gene_name": "Jabba", "organism": "Fruit fly", "refseq_name": "jabba, isoform C", "refseq_ac": [ { "id": "NP_001137703", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137703", "type": "external" } ], "gene_names_uniprotkb": "Jabba; 141242_at; BP1008; CG15092; CG34020; CG42351; Dmel\\CG42351; Dmel_CG42351; anon-WO0118547.167; jabba", "gene_names_refseq": "141242_at; BP1008; CG15092; CG34020; CG42351; Dmel\\CG42351; Jabba; anon-WO0118547.167; jabba", "protein_names_uniprotkb": "Jabba, isoform C", "protein_names_refseq": "CG42351-PC; Jabba-PC; jabba, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42351)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005886 plasma membrane", "go_biological_process": "GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZK5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z7P5-1", "uniprot_id": [ { "id": "A1Z7P5_DROME", "url": "https://www.uniprot.org/uniprot/A1Z7P5", "type": "external" } ], "mass": 70279.0, "length": 640, "protein_name": "Suppressor of variegation 2-10, isoform I", "gene_name": "Su(var)2-10", "organism": "Fruit fly", "refseq_name": "suppressor of variegation 2-10, isoform I", "refseq_ac": [ { "id": "NP_724749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724749", "type": "external" } ], "gene_names_uniprotkb": "Su(var)2-10; CG8068; CLOT2057; DPIAS; DmPias; Dmel\\CG8068; Dmel_CG8068; Dpias; PIAS; SU(VAR)2-10; Su(Var)2-10; Su(var)-10; Su-var(2)10; Suvar(2)10; Sv210; ZIMP; ZimpA; ZimpB; dPIAS; dpias; i184; l(2)03697; pias; zimp", "gene_names_refseq": "CG8068; CLOT2057; DPIAS; DmPias; Dmel\\CG8068; Dpias; PIAS; SU(VAR)2-10; Su(Var)2-10; Su(var)-10; Su(var)2-10; Su-var(2)10; Suvar(2)10; Sv210; ZIMP; ZimpA; ZimpB; dPIAS; dpias; i184; l(2)03697; pias; zimp", "protein_names_uniprotkb": "Suppressor of variegation 2-10, isoform I", "protein_names_refseq": "CG8068-PI; Su(var)2-10-PI; protein inhibitor of activated STAT; suppressor of variegation 2-10, isoform I; suppressor of variegation 2-10; zinc finger-containing Miz1 PIAS3-like", "tax_id": 7227, "disease": "focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); hematologic cancer (Disease Ontology:DOID:2531)", "pathway": " (dme:Dmel_CG8068); (R-DME-196791); (R-DME-210671); (R-DME-3232118); (R-DME-3899300); (R-DME-4090294); (R-DME-4551638); (R-DME-4615885); (R-DME-4755510); (R-DME-5696395)", "pathway_count": 10, "publication_count": 18, "publication_id_list": "10731132;10805787;11390354;11504941;12537568;12537572;12537573;12537574;15659391;16110336;16401426;17569856;17569867;25589440;26109356;26109357;9388184;9770450", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016746 acyltransferase activity;GO:0140096 catalytic activity, acting on a protein;GO:0097677 STAT family protein binding;GO:0061665 SUMO ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0048749 compound eye development;GO:0016925 protein sumoylation;GO:0050829 defense response to Gram-negative bacterium;GO:0045089 positive regulation of innate immune response;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "A1Z7P5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z7Q5-1", "uniprot_id": [ { "id": "A1Z7Q5_DROME", "url": "https://www.uniprot.org/uniprot/A1Z7Q5", "type": "external" } ], "mass": 99484.0, "length": 908, "protein_name": "UDENN domain-containing protein", "gene_name": "CG30347; Dmel\\CG18659; anon-WO0118547.140", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_665880", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_665880", "type": "external" } ], "gene_names_uniprotkb": "CG30347; Dmel\\CG18659; anon-WO0118547.140; BcDNA:GH08789; CG18659; CG30347; CG30348; CG8059; Dmel\\CG18659; Dmel_CG18659; anon-WO0118547.140; anon-WO0118547.145", "gene_names_refseq": "BcDNA:GH08789; CG18659; CG30347; CG30348; CG8059; Dmel\\CG18659; anon-WO0118547.140; anon-WO0118547.145", "protein_names_uniprotkb": "UDENN domain-containing protein", "protein_names_refseq": "CG18659-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); asthma (Disease Ontology:DOID:2841); intrinsic asthma (Disease Ontology:DOID:9360); allergic asthma (Disease 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AE33; CG10155; Dm AE33; Dmel\\CG10155; Dmel_CG10155; dSPRED; spred", "gene_names_refseq": "AE33; CG10155; Dm AE33; Dmel\\CG10155; Spred; dSPRED; spred", "protein_names_uniprotkb": "Sprouty-related protein with EVH-1 domain, isoform C", "protein_names_refseq": "CG10155-PC; Spred-PC; Sprouty-related protein with EVH-1 domain, isoform C", "tax_id": 7227, "disease": "Legius syndrome (Disease Ontology:DOID:0070484); Noonan syndrome (Disease Ontology:DOID:3490); achondroplasia (Disease Ontology:DOID:4480)", "pathway": " (R-DME-5658442); (R-DME-5658623)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG11-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG53-1", "uniprot_id": [ { "id": "A0A0B4KG53_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG53", "type": "external" } ], "mass": 224634.0, "length": 2159, "protein_name": "Mucin related 89F, isoform B", "gene_name": "Mur89F", "organism": "Fruit fly", "refseq_name": "mucin related 89F, isoform B", "refseq_ac": [ { "id": "NP_001262662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262662", "type": "external" } ], "gene_names_uniprotkb": "Mur89F; 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CG44090; Dmel_CG44090", "gene_names_refseq": "CG44090; Dmel\\CG44090", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44090-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44090)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KG57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KG70-1", "uniprot_id": [ { "id": "A0A0B4KG70_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KG70", "type": "external" } ], "mass": 100996.0, "length": 922, "protein_name": "Metastasis-associated protein MTA3", "gene_name": "MTA1-like", "organism": "Fruit fly", "refseq_name": "metastasis associated 1-like, isoform D", "refseq_ac": [ { "id": "NP_001262293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262293", "type": "external" } ], "gene_names_uniprotkb": "MTA1-like; CG2244; Dmel\\CG2244; Dmel_CG2244; MTA-1like; MTA-like; MTA1; MTA; dMTA-1; dMTA1-like; dMTA; p120", "gene_names_refseq": "CG2244; Dmel\\CG2244; MTA-1like; MTA-like; MTA1-like; MTA1; MTA; dMTA-1; dMTA1-like; dMTA; p120", "protein_names_uniprotkb": "Metastasis-associated protein MTA3", "protein_names_refseq": "CG2244-PD; MTA-like; MTA1-like-PD; metastasis associated 1-like, isoform D; metastasis-associated-1-like-protein", "tax_id": 7227, "disease": "systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dme:Dmel_CG2244); (R-DME-3214815); (R-DME-3232118); (R-DME-6804758); (R-DME-8943724); (R-DME-9937850); (R-DME-9940951)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. 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"external" } ], "gene_names_uniprotkb": "CD98hc; CG2791; Dmel\\CG2791; Dmel_CG2791; RE39378p; cd98hc", "gene_names_refseq": "CD98hc; CG2791; Dmel\\CG2791; RE39378p; cd98hc", "protein_names_uniprotkb": "alpha-glucosidase; 3.2.1.20", "protein_names_refseq": "CD98 heavy chain, isoform B; CD98hc-PB; CG2791-PB", "tax_id": 7227, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); transitional cell carcinoma (Disease Ontology:DOID:2671); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); stomach carcinoma (Disease Ontology:DOID:5517)", "pathway": " (dme:Dmel_CG2791); (R-DME-210991); (R-DME-352230); (R-DME-71240)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": 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"missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.20", "type": "external" } ], "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:1903801 L-leucine import across plasma membrane;GO:0005975 carbohydrate metabolic process;GO:0015823 phenylalanine transport;GO:1904273 L-alanine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGE4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHC3-1", "uniprot_id": [ { "id": "A0A0B4KHC3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHC3", "type": "external" } ], "mass": 101347.0, "length": 906, "protein_name": "Serine/threonine-protein kinase", "gene_name": "PKD", "organism": "Fruit fly", "refseq_name": "protein kinase D, isoform G", "refseq_ac": [ { "id": "NP_001262705", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262705", "type": "external" } ], "gene_names_uniprotkb": "PKD; 150131_at; CG7125; Dmel\\CG7125; Dmel_CG7125; PKCm; dPKD; pkd", "gene_names_refseq": "150131_at; CG7125; Dmel\\CG7125; PKCm; PKD; dPKD; pkd", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.13", "protein_names_refseq": "CG7125-PG; PKD-PG; protein kinase D, isoform G; protein kinase D", "tax_id": 7227, "disease": "candidiasis (Disease Ontology:DOID:1508); congenital heart disease (Disease Ontology:DOID:1682); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG7125); (R-DME-1660661)", "pathway_count": 2, "publication_count": 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"2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHC3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHI4-1", "uniprot_id": [ { "id": "A0A0B4KHI4_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHI4", "type": "external" } ], "mass": 83012.0, "length": 761, "protein_name": "Syncrip, isoform Q", "gene_name": "Syp", "organism": "Fruit fly", "refseq_name": "syncrip, isoform Q", "refseq_ac": [ { "id": "NP_001262783", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262783", "type": "external" } ], "gene_names_uniprotkb": 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93AB, isoform C", "refseq_ac": [ { "id": "NP_001262793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262793", "type": "external" } ], "gene_names_uniprotkb": "Dhc93AB; CG3723; DHC4C; DHC; Dhc 93AB; Dhc; Dmel\\CG3723; Dmel_CG3723; dhc93AB; dhc", "gene_names_refseq": "CG3723; DHC4C; DHC; Dhc 93AB; Dhc93AB; Dhc; Dmel\\CG3723; dhc93AB; dhc", "protein_names_uniprotkb": "Dynein heavy chain at 93AB, isoform C", "protein_names_refseq": "CG3723-PC; Dhc93AB-PC; dynein heavy chain at 93AB, isoform C; dynein-related heavy chain polypeptide", "tax_id": 7227, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); atrioventricular septal defect (Disease Ontology:DOID:0050651); primary ciliary dyskinesia 7 (Disease Ontology:DOID:0110605); primary ciliary dyskinesia 40 (Disease Ontology:DOID:0111853); spermatogenic failure 39 (Disease Ontology:DOID:0111926); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " 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"filter_code": "0000000.0000111.000100.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KHK0-1", "uniprot_id": [ { "id": "A0A0B4KHK0_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KHK0", "type": "external" } ], "mass": 91746.0, "length": 807, "protein_name": "Dihydroxyacetone phosphate acyltransferase", "gene_name": "Gnpat", "organism": "Fruit fly", "refseq_name": "glyceronephosphate O-acyltransferase, isoform C", "refseq_ac": [ { "id": "NP_001262957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262957", "type": "external" } ], "gene_names_uniprotkb": "Gnpat; 8-1; CG4625; DHAP-AT; DHAPAT; Dhap-at; Dmel\\CG4625; Dmel_CG4625; GNPAT; GPAT; Gpat", "gene_names_refseq": "8-1; CG4625; DHAP-AT; DHAPAT; Dhap-at; Dmel\\CG4625; GNPAT; GPAT; Gnpat; Gpat", "protein_names_uniprotkb": "Dihydroxyacetone phosphate acyltransferase; 2.3.1.42; Glycerone-phosphate O-acyltransferase", "protein_names_refseq": "CG4625-PC; Gnpat-PC; dihydroxyacetone phosphate acyltansferase; dihydroxyacetone phosphate acyltransferase; glycerol 3-phosphate acyltransferase; glycerol-3-phosphate acyltransferase; glycerol-3-phosphate-acyltransferase; glyceronephosphate O-acyltransferase, isoform C", "tax_id": 7227, "disease": "rhizomelic chondrodysplasia punctata type 2 (Disease Ontology:DOID:0110852); disease of mental health (Disease Ontology:DOID:150)", "pathway": " (dme:Dmel_CG4625); (R-DME-1483166); (R-DME-75896); (R-DME-9033241)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Dihydroxyacetonephosphate acyltransferase catalyzing the first step in the biosynthesis of plasmalogens, a subset of phospholipids that differ from other glycerolipids by having an alkyl chain attached through a vinyl ether linkage at the sn-1 position of the glycerol backbone, and which unique physical 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"https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.5.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.26", "type": "external" }, { "id": "2.3.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.-.-", "type": "external" }, { "id": "2.3.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137", "type": "external" }, { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" }, { "id": "5.1.99.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.4", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "5.3.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.21", "type": "external" } ], "go_molecular_function": "GO:0016287 glycerone-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0008611 ether lipid 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BcDNA:HL07889; CG11867; CG30011; CG3459; Dmel\\CG30011; Dmel_CG30011; Gem; anon-AE003830.1; dCP2", "gene_names_refseq": "BcDNA:HL07889; CG11867; CG30011; CG3459; Dmel\\CG30011; Gem; anon-AE003830.1; dCP2; gem", "protein_names_uniprotkb": "Gemini, isoform C", "protein_names_refseq": "CG30011-PC; gem-PC; gemini, isoform C; persephone", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30011)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z851-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8DYN5-1", "uniprot_id": [ { "id": "A8DYN5_DROME", "url": "https://www.uniprot.org/uniprot/A8DYN5", "type": "external" } ], "mass": 24790.0, "length": 232, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9815", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001097434", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097434", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG9815; 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CG45122; Dmel_CG45122", "gene_names_refseq": "CG45122; Dmel\\CG45122", "protein_names_uniprotkb": "Small lysine-rich protein 1", "protein_names_refseq": "CG45122-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45122)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LH46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8DYL3-1", "uniprot_id": [ { "id": "A8DYL3_DROME", "url": "https://www.uniprot.org/uniprot/A8DYL3", "type": "external" } ], "mass": 86260.0, "length": 852, "protein_name": "Verprolin 1, isoform G", "gene_name": "Vrp1", "organism": "Fruit fly", "refseq_name": "verprolin 1, isoform G", "refseq_ac": [ { "id": "NP_001097406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097406", "type": "external" } ], "gene_names_uniprotkb": "Vrp1; CG13503; D-WIP; DWIP; DWiP; DWip; Dm_Vrp1; Dmel\\CG13503; Dmel_CG13503; Sltr; WIP; Wip; dWIP; dwip; sltr; solas; vrp1; vrp; wip", "gene_names_refseq": "CG13503; D-WIP; DWIP; DWiP; DWip; Dm_Vrp1; Dmel\\CG13503; Sltr; Vrp1; WIP; Wip; dWIP; dwip; sltr; solas; vrp1; vrp; wip", "protein_names_uniprotkb": "Verprolin 1, isoform G", "protein_names_refseq": "CG13503-PG; D-WASp-interacting protein; Verprolin1; Vrp1-PG; WASP-interacting protein; WASp interacting protein; drosophila WIP; solitary; veroprolin; verprolin 1, isoform G; verprolin 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13503)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032433 filopodium tip", "go_biological_process": "GO:0048149 behavioral response to ethanol;GO:0007286 spermatid development;GO:0007520 myoblast fusion;GO:0030838 positive regulation of actin filament polymerization;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8DYL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4LHM3-1", "uniprot_id": [ { "id": "A0A0B4LHM3_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4LHM3", "type": "external" } ], "mass": 79021.0, "length": 707, "protein_name": "carboxylesterase", "gene_name": "Est17", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001287487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287487", "type": "external" } ], "gene_names_uniprotkb": "Est17; 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CG18250; CT41273; DG; DmDG; Dmel\\CG18250; Dmel_CG18250; alpha-DG; atu; dgn; dg; dys", "gene_names_refseq": "CG18250; CT41273; DG; Dg; DmDG; Dmel\\CG18250; alpha-DG; atu; dgn; dg; dys", "protein_names_uniprotkb": "Dystroglycan 1; Dystroglycan; Dystrophin-associated glycoprotein 1", "protein_names_refseq": "CG18250-PD; Dg-PD; alphaDystroglycan; atsugari; dystroglican; dystroglycan, isoform D; dystroglycan-like; dystroglycan", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); Fukuyama congenital muscular dystrophy (Disease Ontology:DOID:0050559); muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); autosomal recessive limb-girdle muscular dystrophy type 2D (Disease Ontology:DOID:0110278); autosomal recessive limb-girdle muscular dystrophy type 2P (Disease Ontology:DOID:0110293); congenital muscular dystrophy-dystroglycanopathy type A9 (Disease Ontology:DOID:0111232); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); primary biliary cholangitis (Disease Ontology:DOID:12236); dilated cardiomyopathy (Disease Ontology:DOID:12930); inclusion body myositis (Disease Ontology:DOID:3429); myocardial infarction (Disease Ontology:DOID:5844); muscular atrophy (Disease Ontology:DOID:767); type 2 diabetes mellitus (Disease Ontology:DOID:9352); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (R-DME-3000178); (R-DME-8932504); (R-DME-8932505); (R-DME-8932506); (R-DME-9010553); (R-DME-9913351); (R-DME-9939291)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. 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CG7340; Dmel_CG7340", "gene_names_refseq": "BcDNA:LD41548; CG7340; Dmel\\CG7340; granny-smith; grsm; l(3)c00064", "protein_names_uniprotkb": "Aminopeptidase grsm; 3.4.11.1; Granny smith; LAP; Leucyl aminopeptidase", "protein_names_refseq": "CG7340-PF; Leucyl-aminopeptidase; aminopeptidase; granny smith, isoform F; granny-smith; grsm-PF; lethal (3) c00064", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "10731132;12537572;30802236", "class_list": "", "function": "Catalyzes the removal of unsubstituted N-terminal amino acids from peptides., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0070006 metalloaminopeptidase activity;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0C4FEI8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S0WGX5-1", "uniprot_id": [ { "id": "A0A0S0WGX5_DROME", "url": "https://www.uniprot.org/uniprot/A0A0S0WGX5", "type": "external" } ], "mass": 3083.0, "length": 26, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG46244", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001303331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303331", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG46244; CG46244; Dm_2L:103252; Dmel_CG46244; FBgn0267964", "gene_names_refseq": "CG46244; Dm_2L:103252; Dmel\\CG46244; FBgn0267964", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG46244-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG46244)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WGX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0S0WMT8-1", "uniprot_id": [ { "id": "A0A0S0WMT8_DROME", "url": "https://www.uniprot.org/uniprot/A0A0S0WMT8", "type": "external" } ], "mass": 65111.0, "length": 593, "protein_name": "Allatostatin C receptor 2, isoform F", "gene_name": "AstC-R2", "organism": "Fruit fly", "refseq_name": "allatostatin C receptor 2, isoform F", "refseq_ac": [ { "id": "NP_001303398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303398", "type": "external" } ], "gene_names_uniprotkb": "AstC-R2; ASTC-R2; Aicr2; AlCR-2; AlCR2; AstC R2; AstCR2; CG13702; Dmel\\CG13702; Dmel_CG13702; Drostar2; anon-WO0170980.154; anon-WO0170980.155; lincRNA.610", "gene_names_refseq": "ASTC-R2; Aicr2; AlCR-2; AlCR2; AstC R2; AstC-R2; AstCR2; CG13702; Dmel\\CG13702; Drostar2; anon-WO0170980.154; anon-WO0170980.155; lincRNA.610", "protein_names_uniprotkb": "Allatostatin C receptor 2, isoform F", "protein_names_refseq": "ASC-receptor; AstC-R2-PF; CG13702-PF; allatostatin C receptor 2, isoform F; allatostatin C receptor2; drosophila allatostatin C receptor 2; somatostatin receptor", "tax_id": 7227, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); opioid abuse (Disease Ontology:DOID:11206); sciatic neuropathy (Disease Ontology:DOID:11446); extrahepatic cholestasis (Disease Ontology:DOID:13619); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); drug psychosis (Disease Ontology:DOID:1742); status epilepticus (Disease Ontology:DOID:1824); post-traumatic stress disorder (Disease Ontology:DOID:2055); brain ischemia (Disease Ontology:DOID:2316); opiate dependence (Disease Ontology:DOID:2559); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); cocaine abuse (Disease Ontology:DOID:809); neonatal abstinence syndrome (Disease Ontology:DOID:9828); obesity (Disease Ontology:DOID:9970); drug dependence (Disease Ontology:DOID:9974); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG13702); (R-DME-391908); 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CG12414; CG17552; Dalpha4; Dmel\\CG12414; Dmel_CG12414; alpha4; anon-WO0138359.1; nAChR-alpha80B; nAChRa4; nAChR; nAcRalpha-4; nAcRalpha-80B; nAcRalpha-80; nAcRaplha-80B; redeye; rye", "gene_names_refseq": "CG12414; CG17552; Dalpha4; Dmel\\CG12414; alpha4; anon-WO0138359.1; nAChR-alpha80B; nAChRa4; nAChRalpha4; nAChR; nAcRalpha-4; nAcRalpha-80B; nAcRalpha-80; nAcRaplha-80B; redeye; rye", "protein_names_uniprotkb": "Nicotinic acetylcholine receptor alpha4, isoform H", "protein_names_refseq": "CG12414-PH; Dalpha4; nAChRalpha4-PH; nicotinic acetylcholine receptor alpha 4; nicotinic acetylcholine receptor alpha 80B; nicotinic acetylcholine receptor alpha4, isoform H; nicotinic acetylcholine receptor alpha4; red-eye; redeye", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); autosomal dominant nocturnal frontal lobe epilepsy 4 (Disease Ontology:DOID:0060685); congenital myasthenic syndrome 4A (Disease Ontology:DOID:0110678); congenital myasthenic syndrome 4C (Disease Ontology:DOID:0110679); lung cancer (Disease Ontology:DOID:1324); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312); congenital myasthenic syndrome (Disease Ontology:DOID:3635); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); lung large cell carcinoma (Disease Ontology:DOID:4556); lung small cell carcinoma (Disease Ontology:DOID:5409); cocaine abuse (Disease Ontology:DOID:809); nasopharynx carcinoma (Disease Ontology:DOID:9261); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG12414); (R-DME-629587); (R-DME-629594); (R-DME-629597); (R-DME-6798695)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport;GO:0030431 sleep", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WNY8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8DYD1-1", "uniprot_id": [ { "id": "A8DYD1_DROME", "url": "https://www.uniprot.org/uniprot/A8DYD1", "type": "external" } ], "mass": 90840.0, "length": 837, "protein_name": "Combgap, isoform L", "gene_name": "cg", "organism": "Fruit fly", "refseq_name": "combgap, isoform L", "refseq_ac": [ { "id": "NP_001097306", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097306", "type": "external" } ], "gene_names_uniprotkb": "cg; 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CG12852", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform F", "refseq_ac": [ { "id": "NP_001097953", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097953", "type": "external" } ], "gene_names_uniprotkb": "CG12425; CG12852; CG12425; CG12852; CG34354; CG4787; Dmel\\CG34354; Dmel_CG34354; cg4787", "gene_names_refseq": "CG12425; CG12852; CG34354; CG4787; Dmel\\CG34354; cg4787", "protein_names_uniprotkb": "RRM domain-containing protein", "protein_names_refseq": "CG34354-PF; uncharacterized protein, isoform F", "tax_id": 7227, "disease": "amyotrophic lateral sclerosis type 26 (Disease Ontology:DOID:0081380); transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (dme:Dmel_CG34354)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0140517 protein-RNA adaptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0050684 regulation of mRNA processing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JPX0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1Z1CH00-1", "uniprot_id": [ { "id": "A0A1Z1CH00_DROME", "url": "https://www.uniprot.org/uniprot/A0A1Z1CH00", "type": "external" } ], "mass": 39900.0, "length": 347, "protein_name": "Meiotic 38, isoform C", "gene_name": "mei-38", "organism": "Fruit fly", "refseq_name": "meiotic 38, isoform C", "refseq_ac": [ { "id": "NP_001334676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001334676", "type": "external" } ], "gene_names_uniprotkb": "mei-38; 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CG12077; Dmel\\CG12077; Dmel_CG12077; PIGC", "gene_names_refseq": "CG12077; Dmel\\CG12077; PIG-C; PIGC", "protein_names_uniprotkb": "Phosphatidylinositol glycan anchor biosynthesis class C, isoform C", "protein_names_refseq": "CG12077-PC; PIG-C-PC; phosphatidylinositol glycan anchor biosynthesis class C, isoform C; phosphatidylinositol glycan anchor biosynthesis, class C ortholog", "tax_id": 7227, "disease": "glycosylphosphatidylinositol biosynthesis defect 16 (Disease Ontology:DOID:0081223)", "pathway": " (dme:Dmel_CG12077); (R-DME-162710)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "glycogene;glycosyltransferase", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process;GO:0045313 rhabdomere membrane biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A2U8U156-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z905-1", "uniprot_id": [ { "id": "A1Z905_DROME", "url": "https://www.uniprot.org/uniprot/A1Z905", "type": "external" } ], "mass": 13175.0, "length": 130, "protein_name": "Uncharacterized protein", "gene_name": "NEST:bs09a11", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_725170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725170", "type": "external" } ], "gene_names_uniprotkb": "NEST:bs09a11; 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cognitive disorder (Disease Ontology:DOID:1561); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); schizophrenia (Disease Ontology:DOID:5419); rheumatoid arthritis (Disease Ontology:DOID:7148); malignant pleural mesothelioma (Disease Ontology:DOID:7474); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778)", "pathway": " (dme:Dmel_CG32975); (R-DME-629594)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:0042166 acetylcholine binding;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0016020 membrane;GO:0045202 synapse;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0042391 regulation of membrane potential;GO:0034220 monoatomic ion transmembrane transport;GO:0006812 monoatomic cation transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A499GGQ3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A499JF18-1", "uniprot_id": [ { "id": "A0A499JF18_DROME", "url": "https://www.uniprot.org/uniprot/A0A499JF18", "type": "external" } ], "mass": 133714.0, "length": 1254, "protein_name": "Chronophage, isoform K", "gene_name": "Cph", "organism": "Fruit fly", "refseq_name": "chronophage, isoform K", "refseq_ac": [ { "id": "NP_001356899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001356899", "type": "external" } ], "gene_names_uniprotkb": "Cph; 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CG30472; Dmel_CG30472", "gene_names_refseq": "CG30472; Dmel\\CG30472", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG30472-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30472)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZA08-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZA14-1", "uniprot_id": [ { "id": "A1ZA14_DROME", "url": "https://www.uniprot.org/uniprot/A1ZA14", "type": "external" } ], "mass": 69718.0, "length": 599, "protein_name": "Ionotropic receptor 52a", "gene_name": "Ir52a", "organism": "Fruit fly", "refseq_name": "ionotropic receptor 52a", "refseq_ac": [ { "id": "NP_611041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611041", "type": "external" } ], "gene_names_uniprotkb": "Ir52a; 52a; CG12960; DmelIR52a; Dmel\\CG12960; Dmel_CG12960; IR52a", "gene_names_refseq": "52a; CG12960; DmelIR52a; Dmel\\CG12960; IR52a; Ir52a", "protein_names_uniprotkb": "Ionotropic receptor 52a", "protein_names_refseq": "CG12960-PB; Ir52a-PB; ionotropic receptor 52a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12960)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0009593 detection of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZA14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZA34-1", "uniprot_id": [ { "id": "A1ZA34_DROME", "url": "https://www.uniprot.org/uniprot/A1ZA34", "type": "external" } ], "mass": 58609.0, "length": 526, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG30091", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_725484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725484", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG30091; CG30091; CG8212; Dmel_CG30091; SP49", "gene_names_refseq": "CG30091; CG8212; Dmel\\CG30091; SP49", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "CG30091-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30091)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZA34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZA55-1", "uniprot_id": [ { "id": "CGLR1_DROME", "url": "https://www.uniprot.org/uniprot/A1ZA55", "type": "external" } ], "mass": 43386.0, "length": 378, "protein_name": "Cyclic GMP-AMP synthase-like receptor 1", "gene_name": "cGlr1", "organism": "Fruit fly", "refseq_name": "cGAS-like receptor 1", "refseq_ac": [ { "id": "NP_788360", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788360", "type": "external" } ], "gene_names_uniprotkb": "cGlr1; CG12970", "gene_names_refseq": "CG12970; Dm-cGLR1; Dmel\\CG12970; cGLR1; cGlr1", "protein_names_uniprotkb": "Cyclic GMP-AMP synthase-like receptor 1; 2.7.7.-; cGLR1", "protein_names_refseq": "CG12970-PC; cGAS-like receptor 1; cGlr1-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12970)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;34261127;34261128", "class_list": "", "function": "Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (3',2'-cGAMP) from ATP and GTP and plays a key role in antiviral innate immunity (PubMed:34261127, PubMed:34261128). Synthesizes 3',2'-cGAMP in a two-step reaction through production of the linear intermediate pppA(2'-5')pG (PubMed:34261127). Acts as a key sensor of double-stranded RNA (dsRNA), the presence of dsRNA in the cytoplasm being a danger signal that triggers the immune responses (PubMed:34261127). Directly binds dsRNA, activating the nucleotidyltransferase activity, leading to synthesis of 3',2'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the antiviral immune response via activation of the NF-kappa-B transcription factor Rel (Relish) (PubMed:34261127, PubMed:34261128). 3',2'-cGAMP is protected from poxin cleavage (PubMed:34261127)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "2.7.7.86", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.86", "type": "external" } ], "go_molecular_function": "GO:0061501 2',3'-cyclic GMP-AMP synthase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0043330 response to exogenous dsRNA;GO:0098586 cellular response to virus;GO:1902615 immune response involved in response to exogenous dsRNA", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A1ZA55-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZA64-1", "uniprot_id": [ { "id": "A1ZA64_DROME", "url": "https://www.uniprot.org/uniprot/A1ZA64", "type": "external" } ], "mass": 27681.0, "length": 260, "protein_name": "trypsin", "gene_name": "Dmel\\CG8299", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_611066", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611066", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG8299; 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CG15071; Dmel_CG15071", "gene_names_refseq": "CG15071; Dmel\\CG15071", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG15071-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15071)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBC7-1", "uniprot_id": [ { "id": "A1ZBC7_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBC7", "type": "external" } ], "mass": 62187.0, "length": 564, "protein_name": "Transporter", "gene_name": "List", "organism": "Fruit fly", "refseq_name": "Lithium-inducible SLC6 transporter, isoform D", "refseq_ac": [ { "id": "NP_611364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611364", "type": "external" } ], "gene_names_uniprotkb": "List; CG15088; DmNAT2; Dmel\\CG15088; Dmel_CG15088; LIST", "gene_names_refseq": "CG15088; DmNAT2; Dmel\\CG15088; LIST; List", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "CG15088-PD; List-PD; Lithium-inducible SLC6 transporter, isoform D", "tax_id": 7227, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); retinitis pigmentosa (Disease Ontology:DOID:10584); multiple system atrophy (Disease Ontology:DOID:4752)", "pathway": " (dme:Dmel_CG15088); (R-DME-352230); (R-DME-442660)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015179 L-amino acid transmembrane transporter activity;GO:0046872 metal ion binding;GO:0005283 amino acid:sodium symporter activity;GO:0005416 amino acid:monoatomic cation symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0010226 response to lithium ion;GO:0035725 sodium ion transmembrane transport;GO:0003333 amino acid transmembrane transport;GO:0006836 neurotransmitter transport;GO:1903804 glycine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBC7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBG2-1", "uniprot_id": [ { "id": "A1ZBG2_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBG2", "type": "external" } ], "mass": 30250.0, "length": 258, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG15115", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_611391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611391", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG15115; CG15115; Dmel_CG15115", "gene_names_refseq": "CG15115; Dmel\\CG15115", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG15115-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15115)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBI2-1", "uniprot_id": [ { "id": "A1ZBI2_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBI2", "type": "external" } ], "mass": 20150.0, "length": 175, "protein_name": "MD-2-related lipid-recognition domain-containing protein", "gene_name": "Dmel\\CG33453", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_995888", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_995888", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG33453; CG33453; Dmel_CG33453", "gene_names_refseq": "CG33453; Dmel\\CG33453", "protein_names_uniprotkb": "MD-2-related lipid-recognition domain-containing protein", "protein_names_refseq": "CG33453-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33453)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBI2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBI6-1", "uniprot_id": [ { "id": "A1ZBI6_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBI6", "type": "external" } ], "mass": 25104.0, "length": 222, "protein_name": "aralkylamine N-acetyltransferase", "gene_name": "AANATL5", "organism": "Fruit fly", "refseq_name": "arylalkylamine N-acetyltransferase-like 5", "refseq_ac": [ { "id": "NP_611403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611403", "type": "external" } ], "gene_names_uniprotkb": "AANATL5; CG10476; Dmel\\CG10476; Dmel_CG10476", "gene_names_refseq": "AANATL5; CG10476; Dmel\\CG10476", "protein_names_uniprotkb": "aralkylamine N-acetyltransferase; 2.3.1.87", "protein_names_refseq": "AANATL5-PA; CG10476-PA; arylalkylamine N-acetyltransferase-like 5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10476)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.87", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.87", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0004059 aralkylamine N-acetyltransferase activity;GO:0008080 N-acetyltransferase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBL9-1", "uniprot_id": [ { "id": "A1ZBL9_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBL9", "type": "external" } ], "mass": 126429.0, "length": 1170, "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "par-1", "organism": "Fruit fly", "refseq_name": "par-1, isoform X", "refseq_ac": [ { "id": "NP_995894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_995894", "type": "external" } ], "gene_names_uniprotkb": "par-1; 27C1; BcDNA:RH48823; CG11960; CG16701; CG30131; CG30132; CG8201; DPAR-1; DPar1; Dmel\\CG8201; Dmel_CG8201; EMK; MARK; PAR-1; PAR1; Par-1; Par1; anon-WO0210402.19; dMARK; dPAR-1; dPAR1; dPar-1; dPar1; l(2)27C1; l(2)k06323; par1", "gene_names_refseq": "27C1; BcDNA:RH48823; CG11960; CG16701; CG30131; CG30132; CG8201; DPAR-1; DPar1; Dmel\\CG8201; EMK; MARK; PAR-1; PAR1; Par-1; Par1; anon-WO0210402.19; dMARK; dPAR-1; dPAR1; dPar-1; dPar1; l(2)27C1; l(2)k06323; par-1; par1", "protein_names_uniprotkb": "MAP/microtubule affinity-regulating kinase 3; 2.7.11.1; Serine/threonine-protein kinase par-1", "protein_names_refseq": "C-TAK1-like; CG8201-PX; ELKL motif kinase; Par-1 kinase; Par-1 protein kinase; lethal (2) 27C1; par-1, isoform X; par-1-PX; partitioning defective-1", "tax_id": 7227, "disease": "visual impairment and progressive phthisis bulbi (Disease Ontology:DOID:0070356); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (R-DME-5673000); (R-DME-5674135); (R-DME-5675221); (R-DME-9856649)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Regulates localization and activity of MITF by mediating its phosphorylation, promoting subsequent interaction between MITF and 14-3-3 and retention in the cytosol. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1. Phosphorylates PKP2 and KSR1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0050321 tau-protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005938 cell cortex;GO:0016323 basolateral plasma membrane;GO:0031594 neuromuscular junction;GO:0045169 fusome;GO:0045172 germline ring canal", "go_biological_process": "GO:0009798 axis specification;GO:0051124 synaptic assembly at neuromuscular junction;GO:0000226 microtubule cytoskeleton organization;GO:0030860 regulation of polarized epithelial cell differentiation;GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBL9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBN7-1", "uniprot_id": [ { "id": "A1ZBN7_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBN7", "type": "external" } ], "mass": 10522.0, "length": 93, "protein_name": "DUF4817 domain-containing protein", "gene_name": "CG15123", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_663311", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_663311", "type": "external" } ], "gene_names_uniprotkb": "CG15123; CG18367; Dmel\\CG18367; Dmel_CG18367", "gene_names_refseq": "CG15123; CG18367; Dmel\\CG18367", "protein_names_uniprotkb": "DUF4817 domain-containing protein", "protein_names_refseq": "CG18367-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18367)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZBU1-1", "uniprot_id": [ { "id": "A1ZBU1_DROME", "url": "https://www.uniprot.org/uniprot/A1ZBU1", "type": "external" } ], "mass": 30184.0, "length": 279, "protein_name": "trypsin", "gene_name": "SP82", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_611479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611479", "type": "external" } ], "gene_names_uniprotkb": "SP82; CG11192; Dmel\\CG11192; Dmel_CG11192", "gene_names_refseq": "CG11192; Dmel\\CG11192; SP82", "protein_names_uniprotkb": "trypsin; 3.4.21.4", "protein_names_refseq": "CG11192-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11192)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A4V2C3-1", "uniprot_id": [ { "id": "A4V2C3_DROME", "url": "https://www.uniprot.org/uniprot/A4V2C3", "type": "external" } ], "mass": 78515.0, "length": 694, "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CG40297; Dmel\\CG17698", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform F", "refseq_ac": [ { "id": "NP_001036633", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036633", "type": "external" } ], "gene_names_uniprotkb": "CG40297; Dmel\\CG17698; CAMKIIB; CAMKIIb; CG17698; CG40297; Dmel\\CG17698; Dmel_CG17698", "gene_names_refseq": "CAMKIIB; CAMKIIb; CG17698; CG40297; Dmel\\CG17698", "protein_names_uniprotkb": "calcium/calmodulin-dependent protein kinase; 2.7.11.17", "protein_names_refseq": "CG17698-PF; uncharacterized protein, isoform F", "tax_id": 7227, "disease": "high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (dme:Dmel_CG17698)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0005509 calcium ion binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A4V2C3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A4V362-1", "uniprot_id": [ { "id": "A4V362_DROME", "url": "https://www.uniprot.org/uniprot/A4V362", "type": "external" } ], "mass": 81941.0, "length": 743, "protein_name": "Solute carrier family 35 member F4", "gene_name": "CG15688; 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Specifically acts as a glutamate mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to glutamate residues on proteins. Does not act on poly-ADP-ribosylated proteins: the poly-ADP-ribose chain of poly-ADP-ribosylated glutamate residues must by hydrolyzed into mono-ADP-ribosylated glutamate by PARG to become a substrate for OARD1. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001883 purine nucleoside binding;GO:0140293 ADP-ribosylglutamate hydrolase activity;GO:0047407 ADP-ribosyl-[dinitrogen reductase] hydrolase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006974 DNA damage response;GO:0042278 purine nucleoside metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JNW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JPF3-1", "uniprot_id": [ { "id": "A8JPF3_DROME", "url": "https://www.uniprot.org/uniprot/A8JPF3", "type": "external" } ], "mass": 55838.0, "length": 511, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "CG12949", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001097728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097728", "type": "external" } ], "gene_names_uniprotkb": "CG12949; CG31411; CG31412; CG34309; CG34409; Dmel\\CG34409; Dmel_CG34409; SP12; c-SP12; cSP12", "gene_names_refseq": "CG12949; CG31411; CG31412; CG34309; CG34409; Dmel\\CG34409; SP12; c-SP12; cSP12", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "CG34409-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34409)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JPF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JQV1-1", "uniprot_id": [ { "id": "A8JQV1_DROME", "url": "https://www.uniprot.org/uniprot/A8JQV1", "type": "external" } ], "mass": 45181.0, "length": 409, "protein_name": "Arrestin C-terminal-like domain-containing protein", "gene_name": "Dmel\\CG18748", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001097703", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097703", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG18748; CG18748; CR18748; Dmel_CG18748", "gene_names_refseq": "CG18748; CR18748; Dmel\\CG18748", "protein_names_uniprotkb": "Arrestin C-terminal-like domain-containing protein", "protein_names_refseq": "CG18748-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "stomach cancer (Disease Ontology:DOID:10534); Reye syndrome (Disease Ontology:DOID:14525); glaucoma (Disease Ontology:DOID:1686); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JQV1-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JQW3-1", "uniprot_id": [ { "id": "A8JQW3_DROME", "url": "https://www.uniprot.org/uniprot/A8JQW3", "type": "external" } ], "mass": 36380.0, "length": 307, "protein_name": "Pinin, isoform B", "gene_name": "Pnn", "organism": "Fruit fly", "refseq_name": "pinin, isoform B", "refseq_ac": [ { "id": "NP_001097727", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097727", "type": "external" } ], "gene_names_uniprotkb": "Pnn; CG8383; Dmel\\CG8383; Dmel_CG8383; FBgn0037737; dPnn", "gene_names_refseq": "CG8383; Dmel\\CG8383; FBgn0037737; Pnn; dPnn", "protein_names_uniprotkb": "Pinin, isoform B", "protein_names_refseq": "CG8383-PB; Pnn-PB; pinin, isoform B; pinin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8383); (R-DME-72163)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JQW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JQW5-1", "uniprot_id": [ { "id": "A8JQW5_DROME", "url": "https://www.uniprot.org/uniprot/A8JQW5", "type": "external" } ], "mass": 47533.0, "length": 424, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG12947", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001097731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097731", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG12947; CG12947; Dmel_CG12947", "gene_names_refseq": "CG12947; Dmel\\CG12947", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG12947-PC; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12947)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JQW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JQY3-1", "uniprot_id": [ { "id": "A8JQY3_DROME", "url": "https://www.uniprot.org/uniprot/A8JQY3", "type": "external" } ], "mass": 77803.0, "length": 695, "protein_name": "Sol1, isoform C", "gene_name": "Sol1", "organism": "Fruit fly", "refseq_name": "Sol1, isoform C", "refseq_ac": [ { "id": "NP_001097756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097756", "type": "external" } ], "gene_names_uniprotkb": "Sol1; 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CG14331; Dmel_CG14331", "gene_names_refseq": "CG14331; Dmel\\CG14331", "protein_names_uniprotkb": "Cupin-like domain-containing protein", "protein_names_refseq": "CG14331-PC; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14331)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016706 2-oxoglutarate-dependent dioxygenase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JR34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JR58-1", "uniprot_id": [ { "id": "A8JR58_DROME", "url": "https://www.uniprot.org/uniprot/A8JR58", "type": "external" } ], "mass": 49976.0, "length": 445, "protein_name": "Hadley, isoform B", "gene_name": "hdly", "organism": "Fruit fly", "refseq_name": "hadley, isoform B", "refseq_ac": [ { "id": "NP_001097851", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097851", "type": "external" } ], "gene_names_uniprotkb": "hdly; CG5630; Dmel\\CG5630; Dmel_CG5630", "gene_names_refseq": "CG5630; Dmel\\CG5630; hdly", "protein_names_uniprotkb": "Hadley, isoform B", "protein_names_refseq": "CG5630-PB; hadley, isoform B; hdly-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5630)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0045434 negative regulation of female receptivity, post-mating", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JR58-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JUR1-1", "uniprot_id": [ { "id": "A8JUR1_DROME", "url": "https://www.uniprot.org/uniprot/A8JUR1", "type": "external" } ], "mass": 244303.0, "length": 2281, "protein_name": "Uncharacterized protein", "gene_name": "CG15207", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_001096948", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096948", "type": "external" } ], "gene_names_uniprotkb": "CG15207; CG11203; CG43901; Dmel\\CG43901; Dmel_CG43901", "gene_names_refseq": "CG11203; CG15207; CG43901; Dmel\\CG43901", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43901-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43901)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JUR1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JUV3-1", "uniprot_id": [ { "id": "A8JUV3_DROME", "url": "https://www.uniprot.org/uniprot/A8JUV3", "type": "external" } ], "mass": 155805.0, "length": 1457, "protein_name": "Nuclear factor of activated T-cells 5", "gene_name": "NFAT", "organism": "Fruit fly", "refseq_name": "NFAT nuclear factor, isoform B", "refseq_ac": [ { "id": "NP_001096974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096974", "type": "external" } ], "gene_names_uniprotkb": "NFAT; CG11172; Dmel\\CG11172; Dmel_CG11172; EP1335; MESR1; NF-AT5; NFAT5; Nfat; dNFAT", "gene_names_refseq": "CG11172; Dmel\\CG11172; EP1335; MESR1; NF-AT5; NFAT5; NFAT; Nfat; dNFAT", "protein_names_uniprotkb": "Nuclear factor of activated T-cells 5; T-cell transcription factor NFAT5", "protein_names_refseq": "CG11172-PB; NFAT homolog; NFAT nuclear factor, isoform B; NFAT-PB; Rel domain protein; drosophila TonEBP; misexpression suppressor of Ras 1", "tax_id": 7227, "disease": "ventricular septal defect (Disease Ontology:DOID:1657); congenital heart disease (Disease Ontology:DOID:1682); aortic valve stenosis (Disease Ontology:DOID:1712); kidney disease (Disease Ontology:DOID:557); osteoarthritis (Disease Ontology:DOID:8398)", "pathway": " (dme:Dmel_CG11172); (R-DME-2025928); (R-DME-2871809); (R-DME-4086398); (R-DME-5607763)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes. Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3'. Mediates the transcriptional response to hypertonicity. Positively regulates the transcription of LCN2 and S100A4 genes; optimal transactivation of these genes requires the presence of DDX5/DDX17. Also involved in the DNA damage response by preventing formation of R-loops; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0005694 chromosome", "go_biological_process": "GO:2000301 negative regulation of synaptic vesicle exocytosis;GO:0048731 system development;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JUV3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JUW4-1", "uniprot_id": [ { "id": "A8JUW4_DROME", "url": "https://www.uniprot.org/uniprot/A8JUW4", "type": "external" } ], "mass": 37574.0, "length": 338, "protein_name": "Lethal (1) G0469, isoform C", "gene_name": "l(1)G0469", "organism": "Fruit fly", "refseq_name": "lethal (1) G0469, isoform C", "refseq_ac": [ { "id": "NP_001096980", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096980", "type": "external" } ], "gene_names_uniprotkb": "l(1)G0469; CG11595; CG12482; CG32597; Dmel\\CG32597; Dmel_CG32597; anon-WO03040301.232", "gene_names_refseq": "CG11595; CG12482; CG32597; Dmel\\CG32597; anon-WO03040301.232; l(1)G0469", "protein_names_uniprotkb": "Lethal (1) G0469, isoform C", "protein_names_refseq": "CG32597-PC; l(1)G0469-PC; lethal (1) G0469, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32597)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JUW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JV41-1", "uniprot_id": [ { "id": "A8JV41_DROME", "url": "https://www.uniprot.org/uniprot/A8JV41", "type": "external" } ], "mass": 68576.0, "length": 591, "protein_name": "Pickpocket 23, isoform C", "gene_name": "ppk23", "organism": "Fruit fly", "refseq_name": "pickpocket 23, isoform C", "refseq_ac": [ { "id": "NP_001097011", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097011", "type": "external" } ], "gene_names_uniprotkb": "ppk23; CG8527; Dmel\\CG8527; Dmel_CG8527; PPK-23; PPK23; Ppk23; ppk-23", "gene_names_refseq": "CG8527; Dmel\\CG8527; PPK-23; PPK23; Ppk23; ppk-23; ppk23", "protein_names_uniprotkb": "Pickpocket 23, isoform C", "protein_names_refseq": "CG8527-PC; pickpocket 23, isoform C; ppk23-PC", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015280 ligand-gated sodium channel activity;GO:0005272 sodium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0008049 male courtship behavior;GO:0035725 sodium ion transmembrane transport;GO:0006814 sodium ion transport;GO:0019236 response to pheromone;GO:0043695 detection of pheromone", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JV41-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8QI13-1", "uniprot_id": [ { "id": "A8QI13_DROME", "url": "https://www.uniprot.org/uniprot/A8QI13", "type": "external" } ], "mass": 24450.0, "length": 213, "protein_name": "Activator of basal transcription 1", "gene_name": "Dmel\\CG40813", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001104071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104071", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG40813; CG40813; CG46504; Dmel\\CG46504; Dmel_CG40813; Dmel_CG46504", "gene_names_refseq": "CG40813; Dmel\\CG40813", "protein_names_uniprotkb": "Activator of basal transcription 1", "protein_names_refseq": "CG40813-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG40813)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0ACD4DAU4", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0034462 small-subunit processome assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8QI13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8QI34-1", "uniprot_id": [ { "id": "A8QI34_DROME", "url": "https://www.uniprot.org/uniprot/A8QI34", "type": "external" } ], "mass": 112401.0, "length": 1009, "protein_name": "Sodium/potassium-transporting ATPase subunit alpha", "gene_name": "JYalpha", "organism": "Fruit fly", "refseq_name": "JYalpha", "refseq_ac": [ { "id": "NP_001104092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104092", "type": "external" } ], "gene_names_uniprotkb": "JYalpha; CG17923; CG40625; CG45760; Dmel\\CG45760; Dmel_CG45760; JY-alpha; JYAlpha; Jyalpha", "gene_names_refseq": "CG17923; CG40625; CG45760; Dmel\\CG45760; JY-alpha; JYAlpha; JYalpha; Jyalpha", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit alpha", "protein_names_refseq": "CG45760-PB; JYalpha-PB; JYalpha", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45760)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005391 P-type sodium:potassium-exchanging transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0090533 cation-transporting ATPase complex;GO:0098797 plasma membrane protein complex", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0006812 monoatomic cation transport;GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8QI34-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8Y589-1", "uniprot_id": [ { "id": "A8Y589_DROME", "url": "https://www.uniprot.org/uniprot/A8Y589", "type": "external" } ], "mass": 20766.0, "length": 178, "protein_name": "Programmed cell death protein 6", "gene_name": "Alg-2", "organism": "Fruit fly", "refseq_name": "Apoptosis-linked gene-2", "refseq_ac": [ { "id": "NP_001104459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104459", "type": "external" } ], "gene_names_uniprotkb": "Alg-2; ALG-2; CG17661; CG40410; DALG-2; Dmel\\CG40410; Dmel_CG40410", "gene_names_refseq": "ALG-2; Alg-2; CG17661; CG40410; DALG-2; Dmel\\CG40410", "protein_names_uniprotkb": "Programmed cell death protein 6", "protein_names_refseq": "Alg-2-PC; Apoptosis-linked gene-2; CG40410-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG40410)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Has a lower Ca(2+) affinity than isoform 1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0046330 positive regulation of JNK cascade;GO:0051592 response to calcium ion;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8Y589-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B7YZH2-1", "uniprot_id": [ { "id": "B7YZH2_DROME", "url": "https://www.uniprot.org/uniprot/B7YZH2", "type": "external" } ], "mass": 29470.0, "length": 253, "protein_name": "LEM-3-like GIY-YIG domain-containing protein", "gene_name": "Dmel\\CG42391", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001137671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137671", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42391; CG42391; Dmel_CG42391", "gene_names_refseq": "CG42391; Dmel\\CG42391", "protein_names_uniprotkb": "LEM-3-like GIY-YIG domain-containing protein", "protein_names_refseq": "CG42391-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42391)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004520 DNA endonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B7YZJ3-1", "uniprot_id": [ { "id": "B7YZJ3_DROME", "url": "https://www.uniprot.org/uniprot/B7YZJ3", "type": "external" } ], "mass": 7921.0, "length": 69, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42239", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001137692", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137692", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42239; CG42239; Dmel_CG42239", "gene_names_refseq": "CG42239; Dmel\\CG42239", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42239-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42239)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B7YZX2-1", "uniprot_id": [ { "id": "B7YZX2_DROME", "url": "https://www.uniprot.org/uniprot/B7YZX2", "type": "external" } ], "mass": 50968.0, "length": 446, "protein_name": "Inwardly rectifying potassium channel 3, isoform D", "gene_name": "Irk3", "organism": "Fruit fly", "refseq_name": "inwardly rectifying potassium channel 3, isoform D", "refseq_ac": [ { "id": "NP_001137835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137835", "type": "external" } ], "gene_names_uniprotkb": "Irk3; CG10369; Dmel\\CG10369; Dmel_CG10369; dIRK-3; dKirIII; irk3", "gene_names_refseq": "CG10369; Dmel\\CG10369; Irk3; dIRK-3; dKirIII; irk3", "protein_names_uniprotkb": "Inwardly rectifying potassium channel 3, isoform D", "protein_names_refseq": "CG10369-PD; Irk3-PD; inwardly rectifying potassium channel 3, isoform D", "tax_id": 7227, "disease": "metabolic acidosis (Disease Ontology:DOID:0050758); EAST syndrome (Disease Ontology:DOID:0060484); hypertrichotic osteochondrodysplasia Cantu type (Disease Ontology:DOID:0060569); Bartter disease type 2 (Disease Ontology:DOID:0110143); autosomal recessive nonsyndromic deafness 4 (Disease Ontology:DOID:0110498); sensorineural hearing loss (Disease Ontology:DOID:10003); nephrotic syndrome (Disease Ontology:DOID:1184); uveitis (Disease Ontology:DOID:13141); Leber congenital amaurosis (Disease Ontology:DOID:14791); retinal vein occlusion (Disease Ontology:DOID:1727); transient cerebral ischemia (Disease Ontology:DOID:224); reflex epilepsy (Disease Ontology:DOID:2548); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); hypokalemia (Disease Ontology:DOID:4500); epilepsy with generalized tonic-clonic seizures (Disease Ontology:DOID:7725); retinal degeneration (Disease Ontology:DOID:8466); diabetic retinopathy (Disease Ontology:DOID:8947)", "pathway": " (dme:Dmel_CG10369); (R-DME-1296025); (R-DME-1296041); (R-DME-1296053); (R-DME-1296067); (R-DME-382556); (R-DME-422356); (R-DME-5576886); (R-DME-5578775); (R-DME-997272)", "pathway_count": 10, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0006813 potassium ion transport;GO:1990573 potassium ion import across plasma membrane;GO:0035220 wing disc development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZX2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B7Z091-1", "uniprot_id": [ { "id": "B7Z091_DROME", "url": "https://www.uniprot.org/uniprot/B7Z091", "type": "external" } ], "mass": 32037.0, "length": 289, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG10587; 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CG8478; Dmel_CG8478", "gene_names_refseq": "CG8478; Dmel\\CG8478", "protein_names_uniprotkb": "C2H2-type domain-containing protein", "protein_names_refseq": "CG8478-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8478)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E1JIH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JII8-1", "uniprot_id": [ { "id": "E1JII8_DROME", "url": "https://www.uniprot.org/uniprot/E1JII8", "type": "external" } ], "mass": 33799.0, "length": 294, "protein_name": "Transcription factor Ouib", "gene_name": "CG31372", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001163590", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163590", "type": "external" } ], "gene_names_uniprotkb": "CG31372; CG6813; Dmel\\CG6813; Dmel_CG6813", "gene_names_refseq": "CG31372; CG6813; Dmel\\CG6813", "protein_names_uniprotkb": "Transcription factor Ouib", "protein_names_refseq": "CG6813-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6813)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E1JII8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JIR1-1", "uniprot_id": [ { "id": "E1JIR1_DROME", "url": "https://www.uniprot.org/uniprot/E1JIR1", "type": "external" } ], "mass": 51042.0, "length": 442, "protein_name": "Pseudouridylate synthase 1 homolog", "gene_name": "Pus1", "organism": "Fruit fly", "refseq_name": "pseudouridine synthase 1, isoform B", "refseq_ac": [ { "id": "NP_001163664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163664", "type": "external" } ], "gene_names_uniprotkb": "Pus1; CG4159; Dmel\\CG4159; Dmel_CG4159; PUS1", "gene_names_refseq": "CG4159; Dmel\\CG4159; PUS1; Pus1", "protein_names_uniprotkb": "Pseudouridylate synthase 1 homolog; 5.4.99.12; tRNA pseudouridine synthase 1; tRNA pseudouridine(38-40) synthase; tRNA pseudouridylate synthase I; tRNA-uridine isomerase I", "protein_names_refseq": "CG4159-PB; Pus1-PB; pseudouridine synthase 1, isoform B; pseudouridylate synthase 1", "tax_id": 7227, "disease": "myopathy, lactic acidosis, and sideroblastic anemia (Disease Ontology:DOID:0080099); myopathy, lactic acidosis, and sideroblastic anemia 1 (Disease Ontology:DOID:0111185)", "pathway": " (dme:Dmel_CG4159)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Pseudouridylate synthase that catalyzes pseudouridylation of tRNAs and mRNAs. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing. Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 mRNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.4.99.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.12", "type": "external" }, { "id": "5.4.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0160147 tRNA pseudouridine(38-40) synthase activity;GO:0160153 mitochondrial tRNA pseudouridine(27/28) synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0031119 tRNA pseudouridine synthesis;GO:0006397 mRNA processing;GO:0001522 pseudouridine synthesis;GO:1990481 mRNA pseudouridine synthesis;GO:0070902 mitochondrial tRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E1JIR1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JJ79-1", "uniprot_id": [ { "id": "E1JJ79_DROME", "url": "https://www.uniprot.org/uniprot/E1JJ79", "type": "external" } ], "mass": 12389.0, "length": 120, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42544", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001163539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163539", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42544; CG42544; Dmel_CG42544; FBgn0260713; HCD12266", "gene_names_refseq": "CG42544; Dmel\\CG42544; FBgn0260713; HCD12266", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42544-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42544)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E1JJ79-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JJ84-1", "uniprot_id": [ { "id": "E1JJ84_DROME", "url": "https://www.uniprot.org/uniprot/E1JJ84", "type": "external" } ], "mass": 18150.0, "length": 160, "protein_name": "Seminal fluid protein 84E", "gene_name": "Sfp84E", "organism": "Fruit fly", "refseq_name": "seminal fluid protein 84E", "refseq_ac": [ { "id": "NP_001163544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163544", "type": "external" } ], "gene_names_uniprotkb": "Sfp84E; 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CG9753; DmAdoR; Dmel\\CG9753; Dmel_CG9753; adoR; anon-WO0170980.109; anon-WO0170980.110; dADOR; dAdoR", "gene_names_refseq": "AdoR; CG9753; DmAdoR; Dmel\\CG9753; adoR; anon-WO0170980.109; anon-WO0170980.110; dADOR; dAdoR", "protein_names_uniprotkb": "Adenosine receptor, isoform A", "protein_names_refseq": "Ado receptor; AdoR-PA; CG9753-PA; adenosine receptor, isoform A; adenosine receptor", "tax_id": 7227, "disease": "obstructive sleep apnea (Disease Ontology:DOID:0050848); left ventricular failure (Disease Ontology:DOID:0051064); hypertension (Disease Ontology:DOID:10763); myopia (Disease Ontology:DOID:11830); primary pulmonary hypertension (Disease Ontology:DOID:14557); asthma (Disease Ontology:DOID:2841); cerebral infarction (Disease Ontology:DOID:3526); lung disease (Disease Ontology:DOID:850); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG9753); (R-DME-373076); (R-DME-417973); (R-DME-418594); (R-DME-5683826)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001609 G protein-coupled adenosine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045202 synapse", "go_biological_process": "GO:0090281 negative regulation of calcium ion import;GO:0006109 regulation of carbohydrate metabolic process;GO:0007186 G protein-coupled receptor signaling pathway;GO:0008306 associative learning;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VAA2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VAJ7-1", "uniprot_id": [ { "id": "Q9VAJ7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VAJ7", "type": "external" } ], "mass": 64222.0, "length": 550, "protein_name": "Pickpocket 21, isoform A", "gene_name": "ppk21", "organism": "Fruit fly", "refseq_name": "pickpocket 21, isoform A", "refseq_ac": [ { "id": "NP_651704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651704", "type": "external" } ], "gene_names_uniprotkb": "ppk21; CG12048; Dmel\\CG12048; Dmel_CG12048; PPK21; Ppk21", "gene_names_refseq": "CG12048; Dmel\\CG12048; PPK21; Ppk21; ppk21", "protein_names_uniprotkb": "Pickpocket 21, isoform A", "protein_names_refseq": "CG12048-PA; pickpocket 21, isoform A; ppk21-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12048)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005272 sodium channel activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0006814 sodium ion transport;GO:0035725 sodium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VAJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VA44-1", "uniprot_id": [ { "id": "Q9VA44_DROME", "url": "https://www.uniprot.org/uniprot/Q9VA44", "type": "external" } ], "mass": 40938.0, "length": 370, "protein_name": "CLIP domain-containing serine protease", "gene_name": "Dmel\\CG11313; c-SP11", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_651821", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651821", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG11313; c-SP11; CG11313; Dmel\\CG11313; Dmel_CG11313; SP11; c-SP11; cSP11", "gene_names_refseq": "CG11313; Dmel\\CG11313; SP11; c-SP11; cSP11", "protein_names_uniprotkb": "CLIP domain-containing serine protease; 3.4.21.-", "protein_names_refseq": "CG11313-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "intellectual disability (Disease Ontology:DOID:1059)", "pathway": " (dme:Dmel_CG11313)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VA44-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VE45-1", "uniprot_id": [ { "id": "Q9VE45_DROME", "url": "https://www.uniprot.org/uniprot/Q9VE45", "type": "external" } ], "mass": 91282.0, "length": 950, "protein_name": "Mucin 91C, isoform A", "gene_name": "Muc91C", "organism": "Fruit fly", "refseq_name": "mucin 91C, isoform A", "refseq_ac": [ { "id": "NP_650744", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650744", "type": "external" } ], "gene_names_uniprotkb": "Muc91C; 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5-HT-2a; 5-HT2Dro; 5-HT2; 5-HT[2]Dro; 5-HT[[2Dro]]; 5-HT[[2]]Dro; 5-HT[[2]]; 5-HT; 5-ht2Dro; 5HT-R82A; 5HT-dro[[1]]; 5HT2-Dro; 5HT2A; 5HT2Dro; 5HT2a; 5HT2; 5HT[[2Dro]]; CG1056; Dm5-HT2A; Dm5-HT[[2A]]; Dm5HT2; Dmel\\CG1056; Dmel_CG1056; d5-HT2A; d5-HT2; l(3)82CDb", "gene_names_refseq": "5-HT-2a; 5-HT2A; 5-HT2Dro; 5-HT2; 5-HT[2]Dro; 5-HT[[2Dro]]; 5-HT[[2]]Dro; 5-HT[[2]]; 5-HT; 5-ht2Dro; 5HT-R82A; 5HT-dro[[1]]; 5HT2-Dro; 5HT2A; 5HT2Dro; 5HT2a; 5HT2; 5HT[[2Dro]]; CG1056; Dm5-HT2A; Dm5-HT[[2A]]; Dm5HT2; Dmel\\CG1056; d5-HT2A; d5-HT2; l(3)82CDb", "protein_names_uniprotkb": "5-hydroxytryptamine (Serotonin) receptor 2A, isoform B", "protein_names_refseq": "5-HT2A-PB; 5-HT[[2]]Dro receptor; 5-hydroxytryptamine (serotonin) receptor 2A, isoform B; CG1056-PB; lethal (3) 82CDb; serotonin receptor 2a", "tax_id": 7227, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); generalized anxiety disorder (Disease Ontology:DOID:14320); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (dme:Dmel_CG1056)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0001587 Gq/11-coupled serotonin receptor activity;GO:0008227 G protein-coupled amine receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007210 serotonin receptor signaling pathway;GO:2000253 positive regulation of feeding behavior;GO:0007377 germ-band extension;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q8IPN2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KSE9-1", "uniprot_id": [ { "id": "Q7KSE9_DROME", "url": "https://www.uniprot.org/uniprot/Q7KSE9", "type": "external" } ], "mass": 228287.0, "length": 2087, "protein_name": "Down syndrome cell adhesion molecule 3, isoform E", "gene_name": "Dscam3", "organism": "Fruit fly", "refseq_name": "down syndrome cell adhesion molecule 3, isoform E", "refseq_ac": [ { "id": "NP_996226", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996226", "type": "external" } ], "gene_names_uniprotkb": "Dscam3; CG12536; CG31190; CG8106; CT33960; DSCAM; Dmel\\CG31190; Dmel_CG31190; Dscam-like", "gene_names_refseq": "CG12536; CG31190; CG8106; CT33960; DSCAM; Dmel\\CG31190; Dscam-like; Dscam3", "protein_names_uniprotkb": "Down syndrome cell adhesion molecule 3, isoform E", "protein_names_refseq": "CG31190-PE; Dscam3-PE; down syndrome cell adhesion molecule 3, isoform E", "tax_id": 7227, "disease": "ocular motor apraxia, Cogan type (Disease Ontology:DOID:0080849); ocular motility disease (Disease Ontology:DOID:1279)", "pathway": " (dme:Dmel_CG31190); (R-DME-376172)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon", "go_biological_process": "GO:0048812 neuron projection morphogenesis;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0048513 animal organ development;GO:0007417 central nervous system development;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q7KSE9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VBH3-1", "uniprot_id": [ { "id": "Q9VBH3_DROME", "url": "https://www.uniprot.org/uniprot/Q9VBH3", "type": "external" } ], "mass": 102031.0, "length": 920, "protein_name": "Dysfusion, isoform D", "gene_name": "dysf", "organism": "Fruit fly", "refseq_name": "dysfusion, isoform D", "refseq_ac": [ { "id": "NP_733137", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733137", "type": "external" } ], "gene_names_uniprotkb": "dysf; CG12561; CG14552; CG14553; CG14554; CG32474; DYSF; Dmel\\CG32474; Dmel_CG32474; Dysf; Dys; NXFL; dNXFL; dys", "gene_names_refseq": "CG12561; CG14552; CG14553; CG14554; CG32474; DYSF; Dmel\\CG32474; Dysf; Dys; NXFL; dNXFL; dysf; dys", "protein_names_uniprotkb": "Dysfusion, isoform D", "protein_names_refseq": "CG32474-PD; NXF-like-factor; cranky; dysf-PD; dysfusion, isoform D; dysfusion", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32474); (R-DME-9768919)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0046982 protein heterodimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0032991 protein-containing complex;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0007427 epithelial cell migration, open tracheal system;GO:0035147 branch fusion, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VBH3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9NDS9-1", "uniprot_id": [ { "id": "M9NDS9_DROME", "url": "https://www.uniprot.org/uniprot/M9NDS9", "type": "external" } ], "mass": 505892.0, "length": 4611, "protein_name": "chitinase", "gene_name": "Cht6", "organism": "Fruit fly", "refseq_name": "chitinase 6, isoform C", "refseq_ac": [ { "id": "NP_001245598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245598", "type": "external" } ], "gene_names_uniprotkb": "Cht6; CG15313; CG15314; CG2989; CG43374; CT5624; Cht; DmCht6; Dmel\\CG43374; Dmel_CG43374; cht6", "gene_names_refseq": "CG15313; CG15314; CG2989; CG43374; CT5624; Cht6; Cht; DmCht6; Dmel\\CG43374; cht6", "protein_names_uniprotkb": "chitinase; 3.2.1.14", "protein_names_refseq": "CG43374-PC; Cht6-PC; chitinase 6, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43374); (R-DME-189085); (R-DME-6798695)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.17", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "3.5.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.28", "type": "external" }, { "id": "3.2.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.14", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.3", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "3.4.17.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.13", "type": "external" }, { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0008843 endochitinase activity;GO:0008061 chitin binding;GO:0004568 chitinase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0000272 polysaccharide catabolic process;GO:0006032 chitin catabolic process;GO:0018990 ecdysis, chitin-based cuticle;GO:0035151 regulation of tube size, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "M9NDS9-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PGH9-1", "uniprot_id": [ { "id": "M9PGH9_DROME", "url": "https://www.uniprot.org/uniprot/M9PGH9", "type": "external" } ], "mass": 355762.0, "length": 3218, "protein_name": "Ca[2+]-channel protein alpha[[1]] subunit T, isoform F", "gene_name": "Ca-alpha1T", "organism": "Fruit fly", "refseq_name": "Ca[2+]-channel protein alpha[[1]] subunit T, isoform F", "refseq_ac": [ { "id": "NP_001259267", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259267", "type": "external" } ], "gene_names_uniprotkb": "Ca-alpha1T; CG12544; CG15899; CG4222; Ca-alphaT-RC; Ca1G; Caalpha1T; DmalphaG; Dmca1G; Dmel\\CG15899; Dmel_CG15899; T-type Ca[2+]; alpha1T; alphaIT; ca-alpha1T; cat", "gene_names_refseq": "CG12544; CG15899; CG4222; Ca-alpha1T; Ca-alphaT-RC; Ca1G; Caalpha1T; DmalphaG; Dmca1G; Dmel\\CG15899; T-type Ca[2+]; alpha1T; alphaIT; ca-alpha1T; cat", "protein_names_uniprotkb": "Ca[2+]-channel protein alpha[[1]] subunit T, isoform F", "protein_names_refseq": "CG15899-PF; Ca-alpha1T-PF; Ca1G; Ca[2+]-channel protein alpha[[1]] subunit T, isoform F", "tax_id": 7227, "disease": "cerebellar ataxia type 42 (Disease Ontology:DOID:0111742); sciatic neuropathy (Disease Ontology:DOID:11446); childhood absence epilepsy (Disease Ontology:DOID:1825); primary hyperaldosteronism (Disease Ontology:DOID:446); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG15899)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008332 low voltage-gated calcium channel activity;GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0005891 voltage-gated calcium channel complex;GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0070588 calcium ion transmembrane transport;GO:0086010 membrane depolarization during action potential;GO:0070509 calcium ion import;GO:0090676 calcium ion transmembrane transport via low voltage-gated calcium channel", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PGH9-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PDW8-1", "uniprot_id": [ { "id": "M9PDW8_DROME", "url": "https://www.uniprot.org/uniprot/M9PDW8", "type": "external" } ], "mass": 580202.0, "length": 5182, "protein_name": "Calponin-homology (CH) domain-containing protein", "gene_name": "CG3950; CG3960; Dmel\\CG34417", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform T", "refseq_ac": [ { "id": "NP_001259282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259282", "type": "external" } ], "gene_names_uniprotkb": "CG3950; CG3960; Dmel\\CG34417; BcDNA:GH23906; CG34417; CG3950; CG3960; Dmel\\CG34417; Dmel_CG34417", "gene_names_refseq": "BcDNA:GH23906; CG34417; CG3950; CG3960; Dmel\\CG34417", "protein_names_uniprotkb": "Calponin-homology (CH) domain-containing protein", "protein_names_refseq": "CG34417-PT; uncharacterized protein, isoform T", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34417)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 31, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 31, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 31, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 39, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007498 mesoderm development;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 4.6, "record_id": "M9PDW8-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KUX2-1", "uniprot_id": [ { "id": "Q7KUX2_DROME", "url": "https://www.uniprot.org/uniprot/Q7KUX2", "type": "external" } ], "mass": 87594.0, "length": 822, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG4829", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_728030", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728030", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG4829; CG4829; Dmel_CG4829", "gene_names_refseq": "CG4829; Dmel\\CG4829", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG4829-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); gamma-glutamyl transpeptidase deficiency (Disease Ontology:DOID:0111257); gestational diabetes (Disease Ontology:DOID:11714); biliary atresia (Disease Ontology:DOID:13608); melanoma (Disease Ontology:DOID:1909); aflatoxins-related hepatocellular carcinoma (Disease Ontology:DOID:5022); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); diabetic neuropathy (Disease Ontology:DOID:9743)", "pathway": " (dme:Dmel_CG4829); (R-DME-174403); (R-DME-2142691); (R-DME-5423646); (R-DME-9753281)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0036374 glutathione hydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006751 glutathione catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q7KUX2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0E8W5-1", "uniprot_id": [ { "id": "Q0E8W5_DROME", "url": "https://www.uniprot.org/uniprot/Q0E8W5", "type": "external" } ], "mass": 14051.0, "length": 119, "protein_name": "Ion transport peptide, isoform C", "gene_name": "ITP", "organism": "Fruit fly", "refseq_name": "Ion transport peptide, isoform C", "refseq_ac": [ { "id": "NP_001036569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036569", "type": "external" } ], "gene_names_uniprotkb": "ITP; BcDNA:SD05282; CG13586; CHH-like; Dmel\\CG13586; Dmel_CG13586; Drm-ITP; DrmITPL1; DrmITPL2; DrmITP; Itp; chgh; itp", "gene_names_refseq": "BcDNA:SD05282; CG13586; CHH-like; Dmel\\CG13586; Drm-ITP; DrmITPL1; DrmITPL2; DrmITP; ITP; Itp; chgh; itp", "protein_names_uniprotkb": "Ion transport peptide, isoform C", "protein_names_refseq": "CG13586-PC; ION TRANSPORT PEPTIDE; ITP-PC; Ion transport peptide, isoform C; ion transport polypeptide", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13586)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007623 circadian rhythm;GO:0045475 locomotor rhythm;GO:0042745 circadian sleep/wake cycle;GO:1903998 regulation of eating behavior", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q0E8W5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86BB0-1", "uniprot_id": [ { "id": "Q86BB0_DROME", "url": "https://www.uniprot.org/uniprot/Q86BB0", "type": "external" } ], "mass": 66232.0, "length": 578, "protein_name": "Male-specific transcript 84B, isoform B", "gene_name": "Mst84B", "organism": "Fruit fly", "refseq_name": "Male-specific transcript 84B, isoform B", "refseq_ac": [ { "id": "NP_788591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788591", "type": "external" } ], "gene_names_uniprotkb": "Mst84B; CG1988; Dmel\\CG1988; Dmel_CG1988", "gene_names_refseq": "CG1988; Dmel\\CG1988; Mst84B", "protein_names_uniprotkb": "Male-specific transcript 84B, isoform B", "protein_names_refseq": "CG1988-PB; Male-specific transcript 84B, isoform B; Mst84B-PB; male specific transcript 84B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1988)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q86BB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9NGP0-1", "uniprot_id": [ { "id": "M9NGP0_DROME", "url": "https://www.uniprot.org/uniprot/M9NGP0", "type": "external" } ], "mass": 80942.0, "length": 790, "protein_name": "Max-binding protein MNT", "gene_name": "Mnt", "organism": "Fruit fly", "refseq_name": "Mnt, isoform I", "refseq_ac": [ { "id": "NP_001245512", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245512", "type": "external" } ], "gene_names_uniprotkb": "Mnt; CG13316; CG2856; DmMnt; Dmel\\CG13316; Dmel_CG13316; EG:114E2.2; MNT; Mad-3E; Mad; bHLHe43; dMad; dMnt; dmnt; mnt", "gene_names_refseq": "CG13316; CG2856; DmMnt; Dmel\\CG13316; EG:114E2.2; MNT; Mad-3E; Mad; Mnt; bHLHe43; dMad; dMnt; dmnt; mnt", "protein_names_uniprotkb": "Max-binding protein MNT; Myc antagonist MNT", "protein_names_refseq": "CG13316-PI; Mnt, isoform I; Mnt-PI", "tax_id": 7227, "disease": "Miller-Dieker lissencephaly syndrome (Disease Ontology:DOID:0060469)", "pathway": " (dme:Dmel_CG13316)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046982 protein heterodimerization activity;GO:0043565 sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0030308 negative regulation of cell growth;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9NGP0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E2QCS3-1", "uniprot_id": [ { "id": "E2QCS3_DROME", "url": "https://www.uniprot.org/uniprot/E2QCS3", "type": "external" } ], "mass": 81124.0, "length": 718, "protein_name": "Methuselah-like 15, isoform C", "gene_name": "mthl15", "organism": "Fruit fly", "refseq_name": "methuselah-like 15, isoform C", "refseq_ac": [ { "id": "NP_723538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_723538", "type": "external" } ], "gene_names_uniprotkb": "mthl15; CG31720; Dmel\\CG31720; Dmel_CG31720", "gene_names_refseq": "CG31720; Dmel\\CG31720; mthl15", "protein_names_uniprotkb": "Methuselah-like 15, isoform C", "protein_names_refseq": "CG31720-PC; methuselah-like 15, isoform C; mthl15-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31720)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E2QCS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E2QD26-1", "uniprot_id": [ { "id": "E2QD26_DROME", "url": "https://www.uniprot.org/uniprot/E2QD26", "type": "external" } ], "mass": 42650.0, "length": 373, "protein_name": "6.3.2.5; Phosphopantothenoylcysteine synthetase, isoform C", "gene_name": "Ppcs", "organism": "Fruit fly", "refseq_name": "phosphopantothenoylcysteine synthetase, isoform C", "refseq_ac": [ { "id": "NP_650784", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650784", "type": "external" } ], "gene_names_uniprotkb": "Ppcs; BcDNA:GH03502; CG5629; Dmel\\CG5629; Dmel_CG5629; GH03502; PPCS; anon-WO0118547.401; dPPCS", "gene_names_refseq": "BcDNA:GH03502; CG5629; Dmel\\CG5629; GH03502; PPCS; Ppcs; anon-WO0118547.401; dPPCS", "protein_names_uniprotkb": "6.3.2.5; Phosphopantothenoylcysteine synthetase, isoform C", "protein_names_refseq": "4'-phosphopantothenoylcysteine synthetase; CG5629-PC; Ppcs-PC; phosphopantothenoylcysteine synthetase, isoform C", "tax_id": 7227, "disease": "dilated cardiomyopathy 2C (Disease Ontology:DOID:0081159); neurodegenerative disease (Disease Ontology:DOID:1289); dilated cardiomyopathy (Disease Ontology:DOID:12930); cancer (Disease Ontology:DOID:162)", "pathway": " (R-DME-196783)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.5", "type": "external" } ], "go_molecular_function": "GO:0004632 phosphopantothenate--cysteine ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0055091 phospholipid homeostasis;GO:0070328 triglyceride homeostasis;GO:0015937 coenzyme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E2QD26-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MRD1-1", "uniprot_id": [ { "id": "MS300_DROME", "url": "https://www.uniprot.org/uniprot/M9MRD1", "type": "external" } ], "mass": 1405148.0, "length": 12345, "protein_name": "Muscle-specific protein 300 kDa", "gene_name": "Msp300", "organism": "Fruit fly", "refseq_name": "Muscle-specific protein 300 kDa, isoform D", "refseq_ac": [ { "id": "NP_001188694", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188694", "type": "external" } ], "gene_names_uniprotkb": "Msp300; BBF-1; Bbbf1; BcDNA:AT10293; BcDNA:GH02446; BcDNA:GH18470; BcDNA:LP10936; CG14035; CG18251; CG18252; CG31649; CG31916; CG33549; CG33715; CG42768; Dmel\\CG42768; Dmel_CG42768; MSP-300; MSP300; Msp-300; Spec25CD; dNesp1; jf22; l(2)25Ch; l(2)jf22; msp-300; msp300", "gene_names_refseq": "BBF-1; Bbbf1; BcDNA:AT10293; BcDNA:GH02446; BcDNA:GH18470; BcDNA:LP10936; CG14035; CG18251; CG18252; CG31649; CG31916; CG33549; CG33715; CG42768; Dmel\\CG42768; MSP-300; MSP300; Msp-300; Msp300; Spec25CD; dNesp1; jf22; l(2)25Ch; l(2)jf22; msp-300; msp300", "protein_names_uniprotkb": "Muscle-specific protein 300 kDa; Nesprin-like protein Msp300", "protein_names_refseq": "Box B-binding factor 1; CG42768-PD; Msp-300; Msp300-PD; Muscle-specific protein 300 kDa, isoform D; Muscle-specific protein 300; Muscle-specific protein, 300 kDa; Muscle-specific protein-300; Nesprin1; lethal(2)25Ch; nesprin; repetitive ORF", "tax_id": 7227, "disease": "cerebellar ataxia (Disease Ontology:DOID:0050753); autosomal dominant Emery-Dreifuss muscular dystrophy 4 (Disease Ontology:DOID:0070249); arthrogryposis multiplex congenita (Disease Ontology:DOID:0080954); arthrogryposis multiplex congenita-3 (Disease Ontology:DOID:0080979); autosomal recessive spinocerebellar ataxia 8 (Disease Ontology:DOID:0111618); Emery-Dreifuss muscular dystrophy (Disease Ontology:DOID:11726); bipolar disorder (Disease Ontology:DOID:3312); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (dme:Dmel_CG42768)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;22927463;25589440;26109356;26109357;32066907;33925313;40245499", "class_list": "", "function": "Component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton (By similarity). Collaborates with klar to promote even spacing of the myonuclei at the periphery of striated muscle fibers by mediating a tight association between a nuclear ring structure of Msp300 and the plus ends of a unique astral MT network (PubMed:22927463). In addition, is essential for anchoring nuclei, mitochondria and endoplasmic reticulum (ER) structures to the Z-disks (PubMed:22927463). In fat body cells, part of perinuclear non-centrosomal microtubule-organizing centers (ncMTOCs) which function to accommodate the organization of microtubule (MT) networks to control nuclear positioning and dynein motor-based retrograde endosomal trafficking (PubMed:32066907). Functions as the primary organizer of the ncMTOC by recruiting Patronin, shot and msps to the organizing center (PubMed:32066907). Within the ncMTOC, Msp300 and shot anchors the ncMTOC at the nuclear surface and recruits the MT minus-end regulators Patronin and Nin for assembly, anchoring and/or stabilization of circumferential and radial MTs at the ncMTOCs (PubMed:32066907). Patronin, and perhaps Nin, recruits msps to the ncMTOC for the gamma-tubulin-independent elongation of radial MTs (PubMed:32066907)., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 8, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0019901 protein kinase binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0005815 microtubule organizing center;GO:0030018 Z disc", "go_biological_process": "GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0040011 locomotion;GO:0051646 mitochondrion localization;GO:0051643 endoplasmic reticulum localization", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "M9MRD1-1", "record_type": "protein", "filter_code": "0000000.0000111.000010.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MRG9-1", "uniprot_id": [ { "id": "M9MRG9_DROME", "url": "https://www.uniprot.org/uniprot/M9MRG9", "type": "external" } ], "mass": 21822.0, "length": 191, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42763", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001188717", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188717", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42763; CG42763; Dmel_CG42763", "gene_names_refseq": "CG42763; Dmel\\CG42763", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42763-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42763)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PB92-1", "uniprot_id": [ { "id": "M9PB92_DROME", "url": "https://www.uniprot.org/uniprot/M9PB92", "type": "external" } ], "mass": 117627.0, "length": 1062, "protein_name": "CCR4-NOT transcription complex subunit 4", "gene_name": "Cnot4", "organism": "Fruit fly", "refseq_name": "CCR4-NOT transcription complex subunit 4, isoform K", "refseq_ac": [ { "id": "NP_001260343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260343", "type": "external" } ], "gene_names_uniprotkb": "Cnot4; CCR4-NOT; CG31716; CG5244; CG5251; Cont4; Dmel\\CG31716; Dmel_CG31716; NOT4; Not4; Q8IPB9_DROME; cg5251; dNOT4; not4", "gene_names_refseq": "CCR4-NOT; CG31716; CG5244; CG5251; Cnot4; Cont4; Dmel\\CG31716; NOT4; Not4; Q8IPB9_DROME; cg5251; dNOT4; not4", "protein_names_uniprotkb": "CCR4-NOT transcription complex subunit 4; 2.3.2.27; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4", "protein_names_refseq": "CCR4-NOT transcription complex subunit 4, isoform K; CG31716-PK; Cnot4-PK; cnot 4 homologue", "tax_id": 7227, "disease": "heart disease (Disease Ontology:DOID:114)", "pathway": " (dme:Dmel_CG31716)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;30692204", "class_list": "", "function": "Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030014 CCR4-NOT complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "M9PB92-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MRL1-1", "uniprot_id": [ { "id": "M9MRL1_DROME", "url": "https://www.uniprot.org/uniprot/M9MRL1", "type": "external" } ], "mass": 6646.0, "length": 54, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42866", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001188853", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188853", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42866; CG42866; Dmel_CG42866", "gene_names_refseq": "CG42866; Dmel\\CG42866", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42866-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42866)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MRL4-1", "uniprot_id": [ { "id": "M9MRL4_DROME", "url": "https://www.uniprot.org/uniprot/M9MRL4", "type": "external" } ], "mass": 18753.0, "length": 161, "protein_name": "Secreted protein", "gene_name": "Dmel\\CG42762", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001188716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188716", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42762; CG42762; Dmel_CG42762", "gene_names_refseq": "CG42762; Dmel\\CG42762", "protein_names_uniprotkb": "Secreted protein", "protein_names_refseq": "CG42762-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42762)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PCU5-1", "uniprot_id": [ { "id": "M9PCU5_DROME", "url": "https://www.uniprot.org/uniprot/M9PCU5", "type": "external" } ], "mass": 51062.0, "length": 448, "protein_name": "3.1.-.-; 3.1.1.3; Lipase 4, isoform C", "gene_name": "Lip4", "organism": "Fruit fly", "refseq_name": "lipase 4, isoform C", "refseq_ac": [ { "id": "NP_001260356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260356", "type": "external" } ], "gene_names_uniprotkb": "Lip4; CG6113; Dmel\\CG6113; Dmel_CG6113; dLip4; dlip4; lip4", "gene_names_refseq": "CG6113; Dmel\\CG6113; Lip4; dLip4; dlip4; lip4", "protein_names_uniprotkb": "3.1.-.-; 3.1.1.3; Lipase 4, isoform C", "protein_names_refseq": "CG6113-PC; Lip4-PC; lipase 4, isoform C; lipase 4; lipase4", "tax_id": 7227, "disease": "autosomal recessive congenital ichthyosis 8 (Disease Ontology:DOID:0060717); lysosomal acid lipase deficiency (Disease Ontology:DOID:0080217); Wolman disease (Disease Ontology:DOID:14497); cholesterol ester storage disease (Disease Ontology:DOID:14502)", "pathway": " (dme:Dmel_CG6113); (R-DME-192456); (R-DME-6809371)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0016788 hydrolase activity, acting on ester bonds;GO:0016298 lipase activity;GO:0017171 serine hydrolase activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005811 lipid droplet", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PCU5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MRU4-1", "uniprot_id": [ { "id": "M9MRU4_DROME", "url": "https://www.uniprot.org/uniprot/M9MRU4", "type": "external" } ], "mass": 12257.0, "length": 109, "protein_name": "Seminal fluid protein", "gene_name": "Dmel\\CG42681", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001188812", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188812", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42681; CG42681; Dmel_CG42681", "gene_names_refseq": "CG42681; Dmel\\CG42681", "protein_names_uniprotkb": "Seminal fluid protein", "protein_names_refseq": "CG42681-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42681)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MRV7-1", "uniprot_id": [ { "id": "M9MRV7_DROME", "url": "https://www.uniprot.org/uniprot/M9MRV7", "type": "external" } ], "mass": 309617.0, "length": 2754, "protein_name": "Neurobeachin-like protein 1", "gene_name": "CG1295", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001189048", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189048", "type": "external" } ], "gene_names_uniprotkb": "CG1295; CG1308; CG1332; CG43367; Dmel\\CG43367; Dmel_CG43367", "gene_names_refseq": "CG1295; CG1308; CG1332; CG43367; Dmel\\CG43367", "protein_names_uniprotkb": "Neurobeachin-like protein 1", "protein_names_refseq": "CG43367-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "gray platelet syndrome (Disease Ontology:DOID:0111044)", "pathway": " (dme:Dmel_CG43367); (R-DME-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRV7-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MS08-1", "uniprot_id": [ { "id": "M9MS08_DROME", "url": "https://www.uniprot.org/uniprot/M9MS08", "type": "external" } ], "mass": 11345.0, "length": 101, "protein_name": "Kazal-like domain-containing protein", "gene_name": "Dmel\\CG42714", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001189053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189053", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42714; CG42714; DMG8-chr3L.11.020; Dmel_CG42714", "gene_names_refseq": "CG42714; DMG8-chr3L.11.020; Dmel\\CG42714", "protein_names_uniprotkb": "Kazal-like domain-containing protein", "protein_names_refseq": "CG42714-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42714)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MS08-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MS11-1", "uniprot_id": [ { "id": "M9MS11_DROME", "url": "https://www.uniprot.org/uniprot/M9MS11", "type": "external" } ], "mass": 11009.0, "length": 97, "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "gene_name": "Dmel\\CG42716", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001189116", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189116", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42716; CG42716; Dmel_CG42716", "gene_names_refseq": "CG42716; Dmel\\CG42716", "protein_names_uniprotkb": "BPTI/Kunitz inhibitor domain-containing protein", "protein_names_refseq": "CG42716-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42716)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MS11-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MS20-1", "uniprot_id": [ { "id": "M9MS20_DROME", "url": "https://www.uniprot.org/uniprot/M9MS20", "type": "external" } ], "mass": 29695.0, "length": 271, "protein_name": "3.4.21.-; Jonah 74E", "gene_name": "Jon74E", "organism": "Fruit fly", "refseq_name": "jonah 74E", "refseq_ac": [ { "id": "NP_001189126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189126", "type": "external" } ], "gene_names_uniprotkb": "Jon74E; CG6298; CT19724; Dmel\\CG6298; Dmel_CG6298; SP85", "gene_names_refseq": "CG6298; CT19724; Dmel\\CG6298; Jon74E; SP85", "protein_names_uniprotkb": "3.4.21.-; Jonah 74E", "protein_names_refseq": "CG6298-PC; Jon74E-PC; jonah 74E", "tax_id": 7227, "disease": "pancreatitis (Disease Ontology:DOID:4989)", "pathway": " (dme:Dmel_CG6298)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0017171 serine hydrolase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MS20-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MS50-1", "uniprot_id": [ { "id": "SRPK7_DROME", "url": "https://www.uniprot.org/uniprot/M9MS50", "type": "external" } ], "mass": 94051.0, "length": 869, "protein_name": "Serine-arginine protein kinase at 79D", "gene_name": "Srpk79D", "organism": "Fruit fly", "refseq_name": "Serine-arginine protein kinase at 79D, isoform F", "refseq_ac": [ { "id": "NP_001189161", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189161", "type": "external" } ], "gene_names_uniprotkb": "Srpk79D; BEST:CK01209; CG11489; CG9085; CK01209; Dmel\\CG11489; Dmel_CG11489; SRPK1; SRPK79D; SRPK; atc; srpk79D; srpk79d", "gene_names_refseq": "BEST:CK01209; CG11489; CG9085; CK01209; Dmel\\CG11489; SRPK1; SRPK79D; SRPK; Srpk79D; atc; srpk79D; srpk79d", "protein_names_uniprotkb": "Serine-arginine protein kinase at 79D; 2.7.11.1; Protein air traffic controller", "protein_names_refseq": "CG11489-PF; Serine-arginine protein kinase at 79D, isoform F; Srpk79D-PF; air traffic controller; serine-arginine (SR) protein kinase at location 79D; serine-arginine protein kinase at 79D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11489)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;19771148;19851455;25589440;26109356;26109357;28606304;30745339;38738619", "class_list": "", "function": "Able to prevent premature assembly of presynaptic active zone cytomatrix (T-bar) electron-dense structure components during axonal transport., [UniProtKB, PubMed]; Serine-arginine protein-specific kinase (PubMed:19851455). Phosphorylates the active zone T-bar structural protein brp/bruchpilot; phosphorylation within the N-terminal region of brp is involved in regulating T-bar component trafficking and assembly (PubMed:30745339). Required to prevent premature assembly of presynaptic active zone cytomatrix (T-bar) electron-dense structure components during axonal transport (PubMed:19771148, PubMed:19851455). Functions downstream of Lrp4 in presynaptic active zone organization (PubMed:28606304, PubMed:38738619)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M9PDA8;Q8T3S1;Q9VNU9;Q9VNV0", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0030424 axon;GO:0043204 perikaryon;GO:0043679 axon terminus;GO:0048786 presynaptic active zone;GO:0005634 nucleus", "go_biological_process": "GO:0048789 cytoskeletal matrix organization at active zone;GO:1990709 presynaptic active zone organization;GO:0051124 synaptic assembly at neuromuscular junction;GO:0007268 chemical synaptic transmission;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "M9MS50-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MS63-1", "uniprot_id": [ { "id": "M9MS63_DROME", "url": "https://www.uniprot.org/uniprot/M9MS63", "type": "external" } ], "mass": 11694.0, "length": 98, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42766; FBgn0261834", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_001188598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188598", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG42766; FBgn0261834; CG42766; Dmel\\CG42766; Dmel_CG42766; FBgn0261834", "gene_names_refseq": "CG42766; Dmel\\CG42766; FBgn0261834", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42766-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42766)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MS63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0KHR2-1", "uniprot_id": [ { "id": "Q0KHR2_DROME", "url": "https://www.uniprot.org/uniprot/Q0KHR2", "type": "external" } ], "mass": 209666.0, "length": 1918, "protein_name": "Forked, isoform F", "gene_name": "f", "organism": "Fruit fly", "refseq_name": "forked, isoform F", "refseq_ac": [ { "id": "NP_001036284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036284", "type": "external" } ], "gene_names_uniprotkb": "f; 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CG43181; Dmel_CG43181; chrX_244575_245164.0", "gene_names_refseq": "CG43181; Dmel\\CG43181; chrX_244575_245164.0", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43181-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43181)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9NGF1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9NGR4-1", "uniprot_id": [ { "id": "M9NGR4_DROME", "url": "https://www.uniprot.org/uniprot/M9NGR4", "type": "external" } ], "mass": 8437.0, "length": 75, "protein_name": "Uncharacterized protein", "gene_name": "lincRNA.952", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001245539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245539", "type": "external" } ], "gene_names_uniprotkb": "lincRNA.952; CG43137; Dmel\\CG43137; Dmel_CG43137", "gene_names_refseq": "CG43137; Dmel\\CG43137; lincRNA.952", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43137-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43137)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9NGR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PB21-1", "uniprot_id": [ { "id": "M9PB21_DROME", "url": "https://www.uniprot.org/uniprot/M9PB21", "type": "external" } ], "mass": 265971.0, "length": 2410, "protein_name": "Fatty acid synthase", "gene_name": "FASN2", "organism": "Fruit fly", "refseq_name": "fatty acid synthase 2, isoform B", "refseq_ac": [ { "id": "NP_001259986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259986", "type": "external" } ], "gene_names_uniprotkb": "FASN2; 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This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.100", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.100", "type": "external" }, { "id": "1.3.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.39", "type": "external" }, { "id": "2.3.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.38", "type": "external" }, { "id": "2.3.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.39", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "2.3.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.85", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "4.2.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.59", "type": "external" }, { "id": "1.3.1.104", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.104", "type": "external" } ], "go_molecular_function": "GO:0017171 serine hydrolase activity;GO:0031177 phosphopantetheine binding;GO:0004312 fatty acid synthase activity;GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity;GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0071329 cellular response to sucrose stimulus;GO:0006723 cuticle hydrocarbon biosynthetic process;GO:1902321 methyl-branched fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PB21-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PB26-1", "uniprot_id": [ { "id": "M9PB26_DROME", "url": "https://www.uniprot.org/uniprot/M9PB26", "type": "external" } ], "mass": 26919.0, "length": 232, "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG43797", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001260012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260012", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43797; 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CG13784; Dmel\\CG13784; Dmel_CG13784", "gene_names_refseq": "BcDNA:SD10385; CG13784; Dmel\\CG13784", "protein_names_uniprotkb": "Solute carrier family 66 member 2; PQ-loop repeat-containing protein 1", "protein_names_refseq": "CG13784-PF; uncharacterized protein, isoform F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13784)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0005829 cytosol;GO:0032588 trans-Golgi network membrane;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0042147 retrograde transport, endosome to Golgi;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PEZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8IQN7-1", "uniprot_id": [ { "id": "Q8IQN7_DROME", "url": "https://www.uniprot.org/uniprot/Q8IQN7", "type": "external" } ], "mass": 95847.0, "length": 833, "protein_name": "Uncharacterized protein", "gene_name": "CG13035; CG13036", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform E", "refseq_ac": [ { "id": "NP_730167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730167", "type": "external" } ], "gene_names_uniprotkb": "CG13035; CG13036; CG13035; CG13036; CG44836; Dmel\\CG44836; Dmel_CG44836", "gene_names_refseq": "CG13035; CG13036; CG44836; Dmel\\CG44836", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44836-PE; rugose; uncharacterized protein, isoform E", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44836)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q8IQN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PD03-1", "uniprot_id": [ { "id": "M9PD03_DROME", "url": "https://www.uniprot.org/uniprot/M9PD03", "type": "external" } ], "mass": 25018.0, "length": 218, "protein_name": "Coiled-coil domain-containing protein 43", "gene_name": "Dmel\\CG9586", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001260279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260279", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG9586; CG9586; Dmel_CG9586", "gene_names_refseq": "CG9586; Dmel\\CG9586", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 43", "protein_names_refseq": "CG9586-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9586)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PD03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PD70-1", "uniprot_id": [ { "id": "M9PD70_DROME", "url": "https://www.uniprot.org/uniprot/M9PD70", "type": "external" } ], "mass": 58492.0, "length": 530, "protein_name": "alkaline phosphatase", "gene_name": "Alp1", "organism": "Fruit fly", "refseq_name": "alkaline phosphatase 1, isoform B", "refseq_ac": [ { "id": "NP_001262159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262159", "type": "external" } ], "gene_names_uniprotkb": "Alp1; APH; Aph-1; Aph; CG5656; Dmel\\CG5656; Dmel_CG5656; l-Aph; p-Aph", "gene_names_refseq": "APH; Alp1; Aph-1; Aph; CG5656; Dmel\\CG5656; l-Aph; p-Aph", "protein_names_uniprotkb": "alkaline phosphatase; 3.1.3.1", "protein_names_refseq": "Alp1-PB; CG5656-PB; alkaline phosphatase 1, isoform B; alkaline phosphatase-1; larval alkaline phosphatase; pupal alkaline phosphatase", "tax_id": 7227, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); adult hypophosphatasia (Disease Ontology:DOID:0110913); infantile hypophosphatasia (Disease Ontology:DOID:0110914); childhood hypophosphatasia (Disease Ontology:DOID:0110915); familial combined hyperlipidemia (Disease Ontology:DOID:13809); hypophosphatasia (Disease Ontology:DOID:14213); arteriosclerosis (Disease Ontology:DOID:2349); uremia (Disease Ontology:DOID:4676); ulcerative colitis (Disease Ontology:DOID:8577); in situ carcinoma (Disease Ontology:DOID:8719); Crohn's disease (Disease Ontology:DOID:8778); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (dme:Dmel_CG5656); (R-DME-1483166); (R-DME-6811438); (R-DME-8935690)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0004035 alkaline phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PD70-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PDR0-1", "uniprot_id": [ { "id": "M9PDR0_DROME", "url": "https://www.uniprot.org/uniprot/M9PDR0", "type": "external" } ], "mass": 168758.0, "length": 1498, "protein_name": "TEP1-F", "gene_name": "Tep4", "organism": "Fruit fly", "refseq_name": "Thioester-containing protein 4, isoform C", "refseq_ac": [ { "id": "NP_001260590", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260590", "type": "external" } ], "gene_names_uniprotkb": "Tep4; CG10363; CT29102; Dmel\\CG10363; Dmel_CG10363; TEP IV; TEP4mel; TEP4; TEPIV; Tep IV; TepIV; dTEPIV; tep4; tepIV", "gene_names_refseq": "CG10363; CT29102; Dmel\\CG10363; TEP IV; TEP4mel; TEP4; TEPIV; Tep IV; Tep4; TepIV; dTEPIV; tep4; tepIV", "protein_names_uniprotkb": "TEP1-F", "protein_names_refseq": "CG10363-PC; TEP; Tep4-PC; Thioester-containing protein 4, isoform C; Thioester-containing protein4; thioester containing protein IV; thiolester containing protein IV", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10363)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Binds covalently through a thioester bond to the pathogen surface resulting in pathogen clearance., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0009620 response to fungus;GO:0007618 mating;GO:0002376 immune system process;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PDR0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PD88-1", "uniprot_id": [ { "id": "M9PD88_DROME", "url": "https://www.uniprot.org/uniprot/M9PD88", "type": "external" } ], "mass": 9971.0, "length": 89, "protein_name": "Copper transport protein ATOX1", "gene_name": "Atox1", "organism": "Fruit fly", "refseq_name": "antioxidant 1 copper chaperone, isoform B", "refseq_ac": [ { "id": "NP_001262184", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262184", "type": "external" } ], "gene_names_uniprotkb": "Atox1; CG12562; CG32446; DmAtox1; Dmel\\CG32446; Dmel_CG32446", "gene_names_refseq": "Atox1; CG12562; CG32446; DmAtox1; Dmel\\CG32446", "protein_names_uniprotkb": "Copper transport protein ATOX1; Metal transport protein ATX1", "protein_names_refseq": "Atox1-PB; CG32446-PB; antioxidant 1 copper chaperone, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32446)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016531 copper chaperone activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006825 copper ion transport;GO:0055070 copper ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PD88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PDL5-1", "uniprot_id": [ { "id": "M9PDL5_DROME", "url": "https://www.uniprot.org/uniprot/M9PDL5", "type": "external" } ], "mass": 19136.0, "length": 163, "protein_name": "Histidine-rich glycoprotein", "gene_name": "Dmel\\CG14052", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001259181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259181", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG14052; CG14052; Dmel_CG14052", "gene_names_refseq": "CG14052; Dmel\\CG14052", "protein_names_uniprotkb": "Histidine-rich glycoprotein", "protein_names_refseq": "CG14052-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14052)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PDL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PDP1-1", "uniprot_id": [ { "id": "M9PDP1_DROME", "url": "https://www.uniprot.org/uniprot/M9PDP1", "type": "external" } ], "mass": 43971.0, "length": 386, "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "Dmel\\CG16781", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001259211", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259211", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG16781; CG16781; Dmel_CG16781", "gene_names_refseq": "CG16781; Dmel\\CG16781", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MARCHF5; 2.3.2.27; Membrane-associated RING finger protein 5; Membrane-associated RING-CH protein V; RING-type E3 ubiquitin transferase MARCHF5", "protein_names_refseq": "CG16781-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG16781)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0090140 regulation of mitochondrial fission;GO:0000209 protein polyubiquitination;GO:0090141 positive regulation of mitochondrial fission", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PDP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PDT0-1", "uniprot_id": [ { "id": "M9PDT0_DROME", "url": "https://www.uniprot.org/uniprot/M9PDT0", "type": "external" } ], "mass": 61336.0, "length": 568, "protein_name": "Uncharacterized protein", "gene_name": "CG12508; CG13966", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001260615", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260615", "type": "external" } ], "gene_names_uniprotkb": "CG12508; CG13966; CG12508; CG13966; CG43861; Dmel\\CG43861; Dmel_CG43861", "gene_names_refseq": "CG12508; CG13966; CG43861; Dmel\\CG43861", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43861-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PDT0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PEC0-1", "uniprot_id": [ { "id": "M9PEC0_DROME", "url": "https://www.uniprot.org/uniprot/M9PEC0", "type": "external" } ], "mass": 61410.0, "length": 556, "protein_name": "Myosuppressin receptor 1, isoform B", "gene_name": "MsR1", "organism": "Fruit fly", "refseq_name": "myosuppressin receptor 1, isoform B", "refseq_ac": [ { "id": "NP_001261324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261324", "type": "external" } ], "gene_names_uniprotkb": "MsR1; CG8985; DMS R1; DMS-R1; DMSR-1; Dm CG8985; Dmel\\CG8985; Dmel_CG8985; DmsR-1; DmsR; MS-R; Ms-R1; Myo R1; anon-WO0170980.106; anon-WO0170980.107", "gene_names_refseq": "CG8985; DMS R1; DMS-R1; DMSR-1; Dm CG8985; Dmel\\CG8985; DmsR-1; DmsR; MS-R; Ms-R1; MsR1; Myo R1; anon-WO0170980.106; anon-WO0170980.107", "protein_names_uniprotkb": "Myosuppressin receptor 1, isoform B", "protein_names_refseq": "CG8985-PB; DMS-receptor1; MsR1-PB; dromyosuppressin receptor 1; myosuppressin receptor 1, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8985)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008528 G protein-coupled peptide receptor activity;GO:0008188 neuropeptide receptor activity;GO:0035013 myosuppressin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0008344 adult locomotory behavior", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PEC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PEP7-1", "uniprot_id": [ { "id": "M9PEP7_DROME", "url": "https://www.uniprot.org/uniprot/M9PEP7", "type": "external" } ], "mass": 25572.0, "length": 230, "protein_name": "Chitin-binding type-2 domain-containing protein", "gene_name": "CG8473", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001259580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259580", "type": "external" } ], "gene_names_uniprotkb": "CG8473; CG33173; CG43673; Dmel\\CG43673; Dmel_CG43673", "gene_names_refseq": "CG33173; CG43673; CG8473; Dmel\\CG43673", "protein_names_uniprotkb": "Chitin-binding type-2 domain-containing protein", "protein_names_refseq": "CG43673-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43673)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0030312 external encapsulating structure", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PEP7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PEQ7-1", "uniprot_id": [ { "id": "M9PEQ7_DROME", "url": "https://www.uniprot.org/uniprot/M9PEQ7", "type": "external" } ], "mass": 51570.0, "length": 470, "protein_name": "C2H2-type domain-containing protein", "gene_name": "Dmel\\CG13287", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001261454", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261454", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13287; CG13287; Dmel_CG13287", "gene_names_refseq": "CG13287; Dmel\\CG13287", "protein_names_uniprotkb": "C2H2-type domain-containing protein", "protein_names_refseq": "CG13287-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "progressive myoclonus epilepsy 10 (Disease Ontology:DOID:0111445)", "pathway": " (dme:Dmel_CG13287)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PEQ7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PEU1-1", "uniprot_id": [ { "id": "M9PEU1_DROME", "url": "https://www.uniprot.org/uniprot/M9PEU1", "type": "external" } ], "mass": 62469.0, "length": 572, "protein_name": "Amino acid transporter transmembrane domain-containing protein", "gene_name": "coch", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform G", "refseq_ac": [ { "id": "NP_001261694", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261694", "type": "external" } ], "gene_names_uniprotkb": "coch; CG34239; CG43693; CG6327; Dmel\\CG43693; Dmel_CG43693", "gene_names_refseq": "CG34239; CG43693; CG6327; Dmel\\CG43693", "protein_names_uniprotkb": "Amino acid transporter transmembrane domain-containing protein", "protein_names_refseq": "CG43693-PG; uncharacterized protein, isoform G", "tax_id": 7227, "disease": "iminoglycinuria (Disease Ontology:DOID:0112265)", "pathway": " (dme:Dmel_CG43693); (R-DME-352230); (R-DME-428559); (R-DME-71240)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005774 vacuolar membrane;GO:0016020 membrane", "go_biological_process": "GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PEU1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PEV1-1", "uniprot_id": [ { "id": "M9PEV1_DROME", "url": "https://www.uniprot.org/uniprot/M9PEV1", "type": "external" } ], "mass": 59702.0, "length": 520, "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG8564", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001261514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261514", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG8564; CG8564; Dmel_CG8564", "gene_names_refseq": "CG8564; Dmel\\CG8564", "protein_names_uniprotkb": "Peptidase M14 domain-containing protein", "protein_names_refseq": "CG8564-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8564); (R-DME-2022377)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PEV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0E8S7-1", "uniprot_id": [ { "id": "Q0E8S7_DROME", "url": "https://www.uniprot.org/uniprot/Q0E8S7", "type": "external" } ], "mass": 57354.0, "length": 531, "protein_name": "Homer, isoform E", "gene_name": "homer", "organism": "Fruit fly", "refseq_name": "homer, isoform E", "refseq_ac": [ { "id": "NP_001036341", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036341", "type": "external" } ], "gene_names_uniprotkb": "homer; BEST:LD03829; CG11324; Dhomer; Dhom; Dm Homer; Dmel\\CG11324; Dmel_CG11324; Dvh; Homer; Hom; LD03829; dhom", "gene_names_refseq": "BEST:LD03829; CG11324; Dhomer; Dhom; Dm Homer; Dmel\\CG11324; Dvh; Homer; Hom; LD03829; dhom; homer", "protein_names_uniprotkb": "Homer, isoform E", "protein_names_refseq": "CG11324-PE; d-Homer; drosophila Ves-1 homolog; homer, isoform E; homer-PE", "tax_id": 7227, "disease": "autosomal dominant nonsyndromic deafness 68 (Disease Ontology:DOID:0110589); alcohol use disorder (Disease Ontology:DOID:1574); anxiety disorder (Disease Ontology:DOID:2030); temporal lobe epilepsy (Disease Ontology:DOID:3328); muscular atrophy (Disease Ontology:DOID:767); cocaine abuse (Disease Ontology:DOID:809); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG11324)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 7, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035256 G protein-coupled glutamate receptor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0030534 adult behavior;GO:0040012 regulation of locomotion;GO:0045471 response to ethanol;GO:0045938 positive regulation of circadian sleep/wake cycle, sleep;GO:0048149 behavioral response to ethanol", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q0E8S7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000001000.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PF00-1", "uniprot_id": [ { "id": "M9PF00_DROME", "url": "https://www.uniprot.org/uniprot/M9PF00", "type": "external" } ], "mass": 70764.0, "length": 644, "protein_name": "Corazonin receptor, isoform B", "gene_name": "CrzR", "organism": "Fruit fly", "refseq_name": "corazonin receptor, isoform B", "refseq_ac": [ { "id": "NP_001261755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261755", "type": "external" } ], "gene_names_uniprotkb": "CrzR; CG10698; CRZR; Crz-R; DCR; DGRHRII; Dmel\\CG10698; Dmel_CG10698; GRH R2; GRH-RII; GRHRII_Dro; GRHRII; anon-WO0170980.196; anon-WO0170980.197; crzR", "gene_names_refseq": "CG10698; CRZR; Crz-R; CrzR; DCR; DGRHRII; Dmel\\CG10698; GRH R2; GRH-RII; GRHRII_Dro; GRHRII; anon-WO0170980.196; anon-WO0170980.197; crzR", "protein_names_uniprotkb": "Corazonin receptor, isoform B", "protein_names_refseq": "CG10698-PB; Crz receptor; CrzR-PB; Drm-AKH receptor-2; GRHRII; corazonin receptor, isoform B; drosophila corazonin receptor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10698)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008188 neuropeptide receptor activity;GO:0035237 corazonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0048149 behavioral response to ethanol;GO:0071361 cellular response to ethanol;GO:0006117 acetaldehyde metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "M9PF00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PF20-1", "uniprot_id": [ { "id": "M9PF20_DROME", "url": "https://www.uniprot.org/uniprot/M9PF20", "type": "external" } ], "mass": 69840.0, "length": 657, "protein_name": "Trailer hitch, isoform H", "gene_name": "tral", "organism": "Fruit fly", "refseq_name": "trailer hitch, isoform H", "refseq_ac": [ { "id": "NP_001261775", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261775", "type": "external" } ], "gene_names_uniprotkb": "tral; BEST:GH08269; CG10686; DmLSm15; Dmel\\CG10686; Dmel_CG10686; LSm15; Lsm15; Scd6p; TRAL; Tral; anon-EST:Posey139; anon-WO0172774.89; anon-WO02059370.24; p67; p70", "gene_names_refseq": "BEST:GH08269; CG10686; DmLSm15; Dmel\\CG10686; LSm15; Lsm15; Scd6p; TRAL; Tral; anon-EST:Posey139; anon-WO0172774.89; anon-WO02059370.24; p67; p70; tral", "protein_names_uniprotkb": "Trailer hitch, isoform H", "protein_names_refseq": "CG10686-PH; Trailer-Hitch; trailer hitch, isoform H; trailer hitch; trailerhitch; tral-PH", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10686)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18765641;25589440;26109356;26109357", "class_list": "", "function": "As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0017151 DEAD/H-box RNA helicase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0043186 P granule;GO:0045169 fusome;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006397 mRNA processing;GO:0030036 actin cytoskeleton organization;GO:0000226 microtubule cytoskeleton organization;GO:0010526 transposable element silencing;GO:0033962 P-body assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "M9PF20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PFG1-1", "uniprot_id": [ { "id": "M9PFG1_DROME", "url": "https://www.uniprot.org/uniprot/M9PFG1", "type": "external" } ], "mass": 79036.0, "length": 699, "protein_name": "Lethal (3) 72Dn, isoform B", "gene_name": "l(3)72Dn", "organism": "Fruit fly", "refseq_name": "lethal (3) 72Dn, isoform B", "refseq_ac": [ { "id": "NP_001261930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261930", "type": "external" } ], "gene_names_uniprotkb": "l(3)72Dn; CG5018; Dmel\\CG5018; Dmel_CG5018; UTP4; l(3)j5A4", "gene_names_refseq": "CG5018; Dmel\\CG5018; UTP4; l(3)72Dn; l(3)j5A4", "protein_names_uniprotkb": "Lethal (3) 72Dn, isoform B", "protein_names_refseq": "CG5018-PB; l(3)72Dn-PB; lethal (3) 72Dn, isoform B", "tax_id": 7227, "disease": "primary biliary cholangitis (Disease Ontology:DOID:12236); cholestasis (Disease Ontology:DOID:13580); liver cirrhosis (Disease Ontology:DOID:5082)", "pathway": " (dme:Dmel_CG5018); (R-DME-6791226)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0034455 t-UTP complex;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PFG1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PFS9-1", "uniprot_id": [ { "id": "M9PFS9_DROME", "url": "https://www.uniprot.org/uniprot/M9PFS9", "type": "external" } ], "mass": 20095.0, "length": 178, "protein_name": "MD-2-related lipid-recognition domain-containing protein", "gene_name": "Dmel\\CG34260", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001262120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262120", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG34260; 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Myosin 10A, isoform D", "gene_name": "Myo10A", "organism": "Fruit fly", "refseq_name": "myosin 10A, isoform D", "refseq_ac": [ { "id": "NP_001036269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036269", "type": "external" } ], "gene_names_uniprotkb": "Myo10A; 10A; AAF47980; CG16922; CG2136; CG2174; CG43657; DmXV; Dmel\\CG43657; Dmel_CG43657; Myo20; Syph; myo10A", "gene_names_refseq": "10A; AAF47980; CG16922; CG2136; CG2174; CG43657; DmXV; Dmel\\CG43657; Myo10A; Myo20; Syph; myo10A", "protein_names_uniprotkb": "5.6.1.8; Myosin 10A, isoform D", "protein_names_refseq": "CG43657-PD; Myo10A-PD; myosin 10A, isoform D; myosin XV; sisyphus; unconventional myosin class XV", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 3 (Disease Ontology:DOID:0110488); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": " (dme:Dmel_CG43657)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0000146 microfilament motor activity;GO:0005524 ATP binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0043025 neuronal cell body;GO:0030175 filopodium;GO:0071944 cell periphery", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0046847 filopodium assembly;GO:0009887 animal organ morphogenesis;GO:0030182 neuron differentiation;GO:0007391 dorsal closure", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q0KHU0-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PGZ8-1", "uniprot_id": [ { "id": "M9PGZ8_DROME", "url": "https://www.uniprot.org/uniprot/M9PGZ8", "type": "external" } ], "mass": 379848.0, "length": 3607, "protein_name": "Smrter, isoform G", "gene_name": "Smr", "organism": "Fruit fly", "refseq_name": "smrter, isoform G", "refseq_ac": [ { "id": "NP_001259491", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259491", "type": "external" } ], "gene_names_uniprotkb": "Smr; CG12719; CG4013; Dmel\\CG4013; Dmel_CG4013; E52; SMRTER; SMR; anon-WO0153538.73; l(1)G0060; l(1)G0361; lincRNA.983; smr", "gene_names_refseq": "CG12719; CG4013; Dmel\\CG4013; E52; SMRTER; SMR; Smr; anon-WO0153538.73; l(1)G0060; l(1)G0361; lincRNA.983; smr", "protein_names_uniprotkb": "Smrter, isoform G", "protein_names_refseq": "CG4013-PG; SANT domain protein; SMRT-related ecdysone receptor interacting factor; SMRT-related ecdysone receptor-interacting factor; Smr-PG; lethal (1) G0060; silencing mediator of retinoid and thyroid hormone receptors-related ecdysone receptor-interacting factor; smarter; smrter, isoform G; smrter", "tax_id": 7227, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); breast cancer (Disease Ontology:DOID:1612); endometrial carcinoma (Disease Ontology:DOID:2871); myelofibrosis (Disease Ontology:DOID:4971); osteoarthritis (Disease Ontology:DOID:8398)", "pathway": " (dme:Dmel_CG4013); (R-DME-2173795); (R-DME-350054); (R-DME-381340); (R-DME-383280); (R-DME-400206); (R-DME-9029569); (R-DME-9623433); (R-DME-9707564); (R-DME-9841922)", "pathway_count": 10, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0017053 transcription repressor complex;GO:0000785 chromatin;GO:0005700 polytene chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007346 regulation of mitotic cell cycle;GO:0030707 follicle cell of egg chamber development;GO:0035220 wing disc development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PGZ8-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PHH9-1", "uniprot_id": [ { "id": "M9PHH9_DROME", "url": "https://www.uniprot.org/uniprot/M9PHH9", "type": "external" } ], "mass": 8261.0, "length": 75, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG43841", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001259681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259681", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG43841; CG32551; CG43841; Dmel_CG43841", "gene_names_refseq": "CG32551; CG43841; Dmel\\CG43841", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43841-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43841)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PHH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PHI8-1", "uniprot_id": [ { "id": "M9PHI8_DROME", "url": "https://www.uniprot.org/uniprot/M9PHI8", "type": "external" } ], "mass": 138057.0, "length": 1280, "protein_name": "Regulator of G-protein signaling 7", "gene_name": "CG32543", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001259691", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259691", "type": "external" } ], "gene_names_uniprotkb": "CG32543; CG42450; CG7095; Dmel\\CG42450; Dmel_CG42450", "gene_names_refseq": "CG32543; CG42450; CG7095; Dmel\\CG42450", "protein_names_uniprotkb": "Regulator of G-protein signaling 7", "protein_names_refseq": "CG42450-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "bradyopsia 1 (Disease Ontology:DOID:0070363); Parkinsonism (Disease Ontology:DOID:0080855)", "pathway": " (dme:Dmel_CG42450); (R-DME-418594); (R-DME-6814122)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007212 G protein-coupled dopamine receptor signaling pathway;GO:0009968 negative regulation of signal transduction;GO:0008277 regulation of G protein-coupled receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PHI8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PI02-1", "uniprot_id": [ { "id": "M9PI02_DROME", "url": "https://www.uniprot.org/uniprot/M9PI02", "type": "external" } ], "mass": 43193.0, "length": 424, "protein_name": "Beadex, isoform D", "gene_name": "Bx", "organism": "Fruit fly", "refseq_name": "beadex, isoform D", "refseq_ac": [ { "id": "NP_001259687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259687", "type": "external" } ], "gene_names_uniprotkb": "Bx; Bd; CG10548; CG15048; CG44425; CG6500; DLMO; Dlmo; Dmel\\CG44425; Dmel_CG44425; LMO; Lmo; Ptd; Rho; bx; dLMO(Beadex); dLMO; dLmo (Bx); dLmo; dlmo; dttg; fliH; hdp-a; hdp; hld", "gene_names_refseq": "Bd; Bx; CG10548; CG15048; CG44425; CG6500; DLMO; Dlmo; Dmel\\CG44425; LMO; Lmo; Ptd; Rho; beadex/dLMO; bx; dLMO(Beadex); dLMO; dLmo (Bx); dLmo; dlmo; dttg; fliH; hdp-a; hdp; hld", "protein_names_uniprotkb": "Beadex, isoform D", "protein_names_refseq": "Bx-PD; CG44425-PD; LIM-only; beadex, isoform D; beadex; flightless-H; held-up; heldup a; pointedoid; rhombotin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44425); (R-DME-8939236)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0035483 gastric emptying;GO:0045893 positive regulation of DNA-templated transcription;GO:0042220 response to cocaine;GO:0045475 locomotor rhythm;GO:0007476 imaginal disc-derived wing morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "M9PI02-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PI06-1", "uniprot_id": [ { "id": "M9PI06_DROME", "url": "https://www.uniprot.org/uniprot/M9PI06", "type": "external" } ], "mass": 45818.0, "length": 414, "protein_name": "Band 7 domain-containing protein", "gene_name": "CG14192; CG7633", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001259699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259699", "type": "external" } ], "gene_names_uniprotkb": "CG14192; CG7633; BEST:CK01423; CG14192; CG33253; CG7633; CK01423; Dmel\\CG33253; Dmel_CG33253", "gene_names_refseq": "BEST:CK01423; CG14192; CG33253; CG7633; CK01423; Dmel\\CG33253", "protein_names_uniprotkb": "Band 7 domain-containing protein", "protein_names_refseq": "CG33253-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "nephrotic syndrome (Disease Ontology:DOID:1184)", "pathway": " (dme:Dmel_CG33253); (R-DME-6798695); (R-DME-8980692); (R-DME-9013406); (R-DME-9013407)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008200 ion channel inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PI06-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PI08-1", "uniprot_id": [ { "id": "M9PI08_DROME", "url": "https://www.uniprot.org/uniprot/M9PI08", "type": "external" } ], "mass": 67295.0, "length": 663, "protein_name": "Runt related A, isoform D", "gene_name": "RunxA", "organism": "Fruit fly", "refseq_name": "runt related A, isoform D", "refseq_ac": [ { "id": "NP_001259747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259747", "type": "external" } ], "gene_names_uniprotkb": "RunxA; CG1379; CG15453; CG34145; Dmel\\CG34145; Dmel_CG34145; RUNXA; RunXA", "gene_names_refseq": "CG1379; CG15453; CG34145; Dmel\\CG34145; RUNXA; RunXA; RunxA", "protein_names_uniprotkb": "Runt related A, isoform D", "protein_names_refseq": "CG34145-PD; RunxA-PD; runt related A, isoform D", "tax_id": 7227, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); inflammatory bowel disease (Disease Ontology:DOID:0050589); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); developmental disorder of mental health (Disease Ontology:DOID:0060037); idiopathic scoliosis (Disease Ontology:DOID:0060250); metaphyseal dysplasia-maxillary hypoplasia-brachydactyly syndrome (Disease Ontology:DOID:0111513); osteonecrosis (Disease Ontology:DOID:10159); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); endometrial cancer (Disease Ontology:DOID:1380); cleidocranial dysplasia (Disease Ontology:DOID:13994); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovary epithelial cancer (Disease Ontology:DOID:2152); ovarian cancer (Disease Ontology:DOID:2394); asthma (Disease Ontology:DOID:2841); endometrial carcinoma (Disease Ontology:DOID:2871); endometriosis (Disease Ontology:DOID:289); invasive ductal carcinoma (Disease Ontology:DOID:3008); colon signet ring adenocarcinoma (Disease Ontology:DOID:3033); middle cerebral artery infarction (Disease Ontology:DOID:3525); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); papillary thyroid carcinoma (Disease Ontology:DOID:3969); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); in situ carcinoma (Disease Ontology:DOID:8719); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (dme:Dmel_CG34145); (R-DME-549127); (R-DME-8877330); (R-DME-8878166); (R-DME-8931987); (R-DME-8934593); (R-DME-8936459); (R-DME-8939236); (R-DME-8939243); (R-DME-8939245); (R-DME-8939246); (R-DME-8939247); (R-DME-8939902); (R-DME-8940973); (R-DME-8941326); (R-DME-9018519)", "pathway_count": 16, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 30, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0003006 developmental process involved in reproduction;GO:0006351 DNA-templated transcription;GO:0048813 dendrite morphogenesis;GO:0001709 cell fate determination;GO:0048592 eye morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PI08-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PI24-1", "uniprot_id": [ { "id": "M9PI24_DROME", "url": "https://www.uniprot.org/uniprot/M9PI24", "type": "external" } ], "mass": 142500.0, "length": 1245, "protein_name": "Anoctamin", "gene_name": "Dmel\\CG6938", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_001261733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261733", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG6938; CG6938; Dmel_CG6938", "gene_names_refseq": "CG6938; Dmel\\CG6938", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "CG6938-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); Miyoshi muscular dystrophy 3 (Disease Ontology:DOID:0070201); dystonia 24 (Disease Ontology:DOID:0090052); autosomal recessive limb-girdle muscular dystrophy type 2L (Disease Ontology:DOID:0110284); Scott syndrome (Disease Ontology:DOID:0111052); isolated elevated serum creatine phosphokinase levels (Disease Ontology:DOID:0111338); gnathodiaphyseal dysplasia (Disease Ontology:DOID:0111533); ankylosing spondylitis (Disease Ontology:DOID:7147)", "pathway": " (dme:Dmel_CG6938); (R-DME-2672351); (R-DME-6798695); (R-DME-9769739); (R-DME-9769743)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0006821 chloride transport;GO:0017121 plasma membrane phospholipid scrambling", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PI24-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PIG4-1", "uniprot_id": [ { "id": "M9PIG4_DROME", "url": "https://www.uniprot.org/uniprot/M9PIG4", "type": "external" } ], "mass": 125467.0, "length": 1107, "protein_name": "Golgi complex-localized glycoprotein 1, isoform B", "gene_name": "Glg1", "organism": "Fruit fly", "refseq_name": "golgi complex-localized glycoprotein 1, isoform B", "refseq_ac": [ { "id": "NP_001262163", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262163", "type": "external" } ], "gene_names_uniprotkb": "Glg1; 120 kDa; 120-kDa; 120KD; 120kDa; CG33214; CG7190; CG7193; CG7195; DG13; Dmel\\CG33214; Dmel_CG33214; GLG1; d120kD; d120kd; d120; dGLG1; gp120; p120-Golgi; p120kD; p120", "gene_names_refseq": "120 kDa; 120-kDa; 120KD; 120kDa; CG33214; CG7190; CG7193; CG7195; DG13; Dmel\\CG33214; GLG1; Glg1; d120kD; d120kd; d120; dGLG1; gp120; p120-Golgi; p120kD; p120", "protein_names_uniprotkb": "Golgi complex-localized glycoprotein 1, isoform B", "protein_names_refseq": "CG33214-PB; Glg1-PB; golgi 120-kDa protein; golgi complex-localized glycoprotein 1, isoform B; golgi complex-localized glycoprotein-1; p120", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33214); (R-DME-202733)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane;GO:0012505 endomembrane system;GO:0005797 Golgi medial cisterna;GO:0000137 Golgi cis cisterna", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PIG4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KVX6-1", "uniprot_id": [ { "id": "Q7KVX6_DROME", "url": "https://www.uniprot.org/uniprot/Q7KVX6", "type": "external" } ], "mass": 155545.0, "length": 1418, "protein_name": "Uncharacterized protein", "gene_name": "CG15240; CG16828; CG16829", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_996345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996345", "type": "external" } ], "gene_names_uniprotkb": "CG15240; CG16828; CG16829; BcDNA:RH43809; CG15240; CG16828; CG16829; CG32776; CG42541; Dmel\\CG42541; Dmel_CG42541", "gene_names_refseq": "BcDNA:RH43809; CG15240; CG16828; CG16829; CG32776; CG42541; Dmel\\CG42541", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42541-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42541)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005246 calcium channel regulator activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q7KVX6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PJ28-1", "uniprot_id": [ { "id": "M9PJ28_DROME", "url": "https://www.uniprot.org/uniprot/M9PJ28", "type": "external" } ], "mass": 110980.0, "length": 987, "protein_name": "Alstrom syndrome 1b, isoform B", "gene_name": "Alms1b", "organism": "Fruit fly", "refseq_name": "alstrom syndrome 1b, isoform B", "refseq_ac": [ { "id": "NP_001259240", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259240", "type": "external" } ], "gene_names_uniprotkb": "Alms1b; CG12184; Dmel\\CG12184; Dmel_CG12184; EG:66A1.3; GH15731P; alms1b", "gene_names_refseq": "Alms1b; CG12184; Dmel\\CG12184; EG:66A1.3; GH15731P; alms1b", "protein_names_uniprotkb": "Alstrom syndrome 1b, isoform B", "protein_names_refseq": "Alms1b-PB; CG12184-PB; alstrom syndrome 1b, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12184)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PJ28-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PJG1-1", "uniprot_id": [ { "id": "M9PJG1_DROME", "url": "https://www.uniprot.org/uniprot/M9PJG1", "type": "external" } ], "mass": 74002.0, "length": 726, "protein_name": "Sp1, isoform F", "gene_name": "Sp1", "organism": "Fruit fly", "refseq_name": "Sp1, isoform F", "refseq_ac": [ { "id": "NP_001259388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259388", "type": "external" } ], "gene_names_uniprotkb": "Sp1; CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\\CG1343; Dmel_CG1343; SP1; dSp1; sp1", "gene_names_refseq": "CG1343; D-Sp1; D-Sp8; D.Sp1; Dmel\\CG1343; SP1; Sp1; dSp1; sp1", "protein_names_uniprotkb": "Sp1, isoform F", "protein_names_refseq": "CG1343-PF; Sp1, isoform F; Sp1-PF", "tax_id": 7227, "disease": "amelogenesis imperfecta type 1K (Disease Ontology:DOID:0060945); osteogenesis imperfecta type 12 (Disease Ontology:DOID:0110348); aortic valve stenosis (Disease Ontology:DOID:1712)", "pathway": " (dme:Dmel_CG1343)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0007480 imaginal disc-derived leg morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9PJG1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KUK9-1", "uniprot_id": [ { "id": "Q7KUK9_DROME", "url": "https://www.uniprot.org/uniprot/Q7KUK9", "type": "external" } ], "mass": 178528.0, "length": 1656, "protein_name": "Uncharacterized protein", "gene_name": "CT39634; Dmel\\CG17839", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_996085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996085", "type": "external" } ], "gene_names_uniprotkb": "CT39634; Dmel\\CG17839; 17839; CG17839; CT39634; Dmel\\CG17839; Dmel_CG17839", "gene_names_refseq": "17839; CG17839; CT39634; Dmel\\CG17839", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG17839-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17839)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q7KUK9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0E8G6-1", "uniprot_id": [ { "id": "Q0E8G6_DROME", "url": "https://www.uniprot.org/uniprot/Q0E8G6", "type": "external" } ], "mass": 26962.0, "length": 237, "protein_name": "Cleavage and polyadenylation specificity factor subunit 5", "gene_name": "Cpsf5", "organism": "Fruit fly", "refseq_name": "cleavage and polyadenylation specific factor 5, isoform C", "refseq_ac": [ { "id": "NP_001036597", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036597", "type": "external" } ], "gene_names_uniprotkb": "Cpsf5; CDI12; CF I[[m]]25; CFI25; CFIm25; CG3689; CPSF5; Cdi12; Dmel\\CG3689; Dmel_CG3689; cdi12", "gene_names_refseq": "CDI12; CF I[[m]]25; CFI25; CFIm25; CG3689; CPSF5; Cdi12; Cpsf5; Dmel\\CG3689; cdi12", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 5", "protein_names_refseq": "CG3689-PC; Cpsf5-PC; Cyclin-dependent kinase interactor 12; cleavage and polyadenylation specific factor 5, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3689); (R-DME-73856); (R-DME-77595); (R-DME-9770562)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035925 mRNA 3'-UTR AU-rich region binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005849 mRNA cleavage factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0031124 mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q0E8G6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0E8N6-1", "uniprot_id": [ { "id": "Q0E8N6_DROME", "url": "https://www.uniprot.org/uniprot/Q0E8N6", "type": "external" } ], "mass": 112705.0, "length": 1002, "protein_name": "Clumsy, isoform B", "gene_name": "clumsy", "organism": "Fruit fly", "refseq_name": "clumsy, isoform B", "refseq_ac": [ { "id": "NP_001036373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036373", "type": "external" } ], "gene_names_uniprotkb": "clumsy; CG8681; CT9037; Clumsy; Dmel\\CG8681; Dmel_CG8681; Dmelclumsy; GluR39B", "gene_names_refseq": "CG8681; CT9037; Clumsy; Dmel\\CG8681; Dmelclumsy; GluR39B; clumsy", "protein_names_uniprotkb": "Clumsy, isoform B", "protein_names_refseq": "CG8681-PB; clumsy, isoform B; clumsy-PB", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder 6 (Disease Ontology:DOID:0081182); Huntington's disease (Disease Ontology:DOID:12858); status epilepticus (Disease Ontology:DOID:1824); childhood absence epilepsy (Disease Ontology:DOID:1825); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (dme:Dmel_CG8681); (R-DME-451307); (R-DME-451308); (R-DME-500657)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015277 kainate selective glutamate receptor activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0008066 glutamate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098839 postsynaptic density membrane;GO:0008328 ionotropic glutamate receptor complex;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0035249 synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission;GO:0060025 regulation of synaptic activity", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q0E8N6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0E8T6-1", "uniprot_id": [ { "id": "Q0E8T6_DROME", "url": "https://www.uniprot.org/uniprot/Q0E8T6", "type": "external" } ], "mass": 16575.0, "length": 159, "protein_name": "DAZ-associated protein 2", "gene_name": "Dmel\\CG34125", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001036334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036334", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG34125; CG31652; CG34125; Dmel_CG34125", "gene_names_refseq": "CG31652; CG34125; Dmel\\CG34125", "protein_names_uniprotkb": "DAZ-associated protein 2; Deleted in azoospermia-associated protein 2; Proline-rich transcript in brain protein", "protein_names_refseq": "CG34125-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34125)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "In unstressed cells, promotes SIAH1-mediated polyubiquitination and degradation of the serine/threonine-protein kinase HIPK2, probably by acting as a loading factor that potentiates complex formation between HIPK2 and ubiquitin ligase SIAH1. In response to DNA damage, localizes to the nucleus following phosphorylation by HIPK2 and modulates the expression of a subset of TP53/p53 target genes by binding to TP53 at target gene promoters. This limits the expression of a number of cell death-mediating TP53 target genes, reducing DNA damage-induced cell death. Enhances the binding of transcription factor TCF7L2/TCF4, a Wnt signaling pathway effector, to the promoters of target genes. Plays a role in stress granule formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016607 nuclear speck;GO:0010494 cytoplasmic stress granule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q0E8T6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0KHY5-1", "uniprot_id": [ { "id": "Q0KHY5_DROME", "url": "https://www.uniprot.org/uniprot/Q0KHY5", "type": "external" } ], "mass": 5638.0, "length": 47, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG34155", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001036778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036778", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG34155; CG34155; Dmel_CG34155", "gene_names_refseq": "CG34155; Dmel\\CG34155", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG34155-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34155)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q0KHY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2MGP3-1", "uniprot_id": [ { "id": "Q2MGP3_DROME", "url": "https://www.uniprot.org/uniprot/Q2MGP3", "type": "external" } ], "mass": 18693.0, "length": 160, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG33666", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001027046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027046", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG33666; CG33666; Dmel_CG33666", "gene_names_refseq": "CG33666; Dmel\\CG33666", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG33666-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33666)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q2MGP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2MGP5-1", "uniprot_id": [ { "id": "Q2MGP5_DROME", "url": "https://www.uniprot.org/uniprot/Q2MGP5", "type": "external" } ], "mass": 18697.0, "length": 160, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG33668", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001027044", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027044", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG33668; 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CG33647; Dmel_CG33647", "gene_names_refseq": "CG33647; Dmel\\CG33647", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG33647-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33647)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q4ABJ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VA06-1", "uniprot_id": [ { "id": "Q9VA06_DROME", "url": "https://www.uniprot.org/uniprot/Q9VA06", "type": "external" } ], "mass": 59932.0, "length": 521, "protein_name": "Slow termination of phototransduction, isoform A", "gene_name": "stops", "organism": "Fruit fly", "refseq_name": "slow termination of phototransduction, isoform A", "refseq_ac": [ { "id": "NP_733416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733416", "type": "external" } ], "gene_names_uniprotkb": "stops; CG15557; CG15558; CG15559; CG31006; Dmel\\CG31006; Dmel_CG31006; su(rdgB)69", "gene_names_refseq": "CG15557; CG15558; CG15559; CG31006; Dmel\\CG31006; stops; su(rdgB)69", "protein_names_uniprotkb": "Slow termination of phototransduction, isoform A", "protein_names_refseq": "CG31006-PA; slow termination of phototransduction, isoform A; stops-PA; suppressor (rdgB) 69", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31006); (R-DME-8951664); (R-DME-983168)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q961U2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007605 sensory perception of sound;GO:0030265 phospholipase C-activating opsin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VA06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KSN8-1", "uniprot_id": [ { "id": "Q7KSN8_DROME", "url": "https://www.uniprot.org/uniprot/Q7KSN8", "type": "external" } ], "mass": 172344.0, "length": 1486, "protein_name": "RNA helicase aquarius", "gene_name": "salsa", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_996198", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996198", "type": "external" } ], "gene_names_uniprotkb": "salsa; CG14729; CG14730; CG31368; Dmel\\CG31368; Dmel_CG31368; Salsa", "gene_names_refseq": "CG14729; CG14730; CG31368; Dmel\\CG31368; Salsa", "protein_names_uniprotkb": "RNA helicase aquarius; 3.6.4.13; Intron-binding protein of 160 kDa", "protein_names_refseq": "CG31368-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31368); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-72163)", "pathway_count": 5, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. 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152685_at; CG3708; Dmel_CG3708; EG:BACR7A4.18", "gene_names_refseq": "152685_at; CG3708; Dmel\\CG3708; EG:BACR7A4.18", "protein_names_uniprotkb": "Nucleosome assembly protein 1-like 4", "protein_names_refseq": "CG3708-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3708)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006334 nucleosome assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q7KW25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7Z2C5-1", "uniprot_id": [ { "id": "Q7Z2C5_DROME", "url": "https://www.uniprot.org/uniprot/Q7Z2C5", "type": "external" } ], "mass": 65250.0, "length": 625, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG12723", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_572864", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572864", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG12723; CG12723; Dmel_CG12723", "gene_names_refseq": "CG12723; Dmel\\CG12723", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG12723-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12723); (R-DME-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q7Z2C5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86BP6-1", "uniprot_id": [ { "id": "ELG1_DROME", "url": "https://www.uniprot.org/uniprot/Q86BP6", "type": "external" } ], "mass": 129367.0, "length": 1162, "protein_name": "Enhanced level of genomic instability 1", "gene_name": "elg1", "organism": "Fruit fly", "refseq_name": "enhanced level of genomic instability 1, isoform C", "refseq_ac": [ { "id": "NP_996103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996103", "type": "external" } ], "gene_names_uniprotkb": "elg1; CG16838", "gene_names_refseq": "CG16838; Dmel\\CG16838; Elg1; elg1", "protein_names_uniprotkb": "Enhanced level of genomic instability 1", "protein_names_refseq": "CG16838-PC; elg1 homolog; elg1-PC; enhanced level of genomic instability 1, isoform C", "tax_id": 7227, "disease": "neurilemmoma (Disease Ontology:DOID:3192)", "pathway": " (dme:Dmel_CG16838)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;27198229", "class_list": "", "function": "Has an important role in DNA replication and in maintaining genome integrity during replication stress (By similarity). Promotes PCNA deubiquitination (By similarity). As component of the Elg1 RFC-like complex, regulates the functions of the DNA polymerase processivity factor PCNA by unloading it from DNA after replication during the S phase of the cell cycle (PubMed:27198229). The PCNA-unloading might be regulated via interaction with the Enok acetyltransferase complex (PubMed:27198229). Might have a role in restarting of stalled/regressed replication forks during replication stress (By similarity). In the ovaries, has a role in nurse cell endoreplication (PubMed:27198229)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q8MSZ2;Q9VUZ2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0061860 DNA clamp unloader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031391 Elg1 RFC-like complex", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q86BP6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8I725-1", "uniprot_id": [ { "id": "Q8I725_DROME", "url": "https://www.uniprot.org/uniprot/Q8I725", "type": "external" } ], "mass": 38375.0, "length": 347, "protein_name": "Glyoxylate reductase/hydroxypyruvate reductase", "gene_name": "Dmel\\CG1236", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_649579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649579", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG1236; CG1236; Dmel_CG1236", "gene_names_refseq": "CG1236; Dmel\\CG1236", "protein_names_uniprotkb": "Glyoxylate reductase/hydroxypyruvate reductase", "protein_names_refseq": "CG1236-PA; uncharacterized protein", "tax_id": 7227, "disease": "primary hyperoxaluria type 2 (Disease Ontology:DOID:0111671); primary hyperoxaluria (Disease Ontology:DOID:2977)", "pathway": " (dme:Dmel_CG1236); (R-DME-389661)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008465 hydroxypyruvate reductase (NADH) activity;GO:0030267 glyoxylate reductase (NADPH) activity;GO:0051287 NAD binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q8I725-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8IMH8-1", "uniprot_id": [ { "id": "Q8IMH8_DROME", "url": "https://www.uniprot.org/uniprot/Q8IMH8", "type": "external" } ], "mass": 52652.0, "length": 453, "protein_name": "Prolyl 4-hydroxylase N-terminal domain-containing protein", "gene_name": "CG9708", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_733392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733392", "type": "external" } ], "gene_names_uniprotkb": "CG9708; 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CG31076; CG6309; CT19744; Dmel_CG31076", "gene_names_refseq": "CG31076; CG6309; CT19744; Dmel\\CG31076", "protein_names_uniprotkb": "Leucine-rich melanocyte differentiation-associated protein", "protein_names_refseq": "CG31076-PB; uncharacterized protein", "tax_id": 7227, "disease": "oculocutaneous albinism type VII (Disease Ontology:DOID:0070100)", "pathway": " (dme:Dmel_CG31076)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0030318 melanocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q8IMQ4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8IMV2-1", "uniprot_id": [ { "id": "Q8IMV2_DROME", "url": "https://www.uniprot.org/uniprot/Q8IMV2", "type": "external" } ], "mass": 64740.0, "length": 561, "protein_name": "Pickpocket 22, isoform B", "gene_name": "ppk22", "organism": "Fruit fly", "refseq_name": "pickpocket 22, isoform B", "refseq_ac": [ { "id": "NP_733051", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733051", "type": "external" } ], "gene_names_uniprotkb": "ppk22; 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AC 3; AC3; CG1506; DAC39E; DAC3; Dmel\\CG1506; Dmel_CG1506; ac3; dADCY3", "gene_names_refseq": "AC 3; AC3; Ac3; CG1506; DAC39E; DAC3; Dmel\\CG1506; ac3; dADCY3", "protein_names_uniprotkb": "adenylate cyclase; 4.6.1.1", "protein_names_refseq": "Ac3-PA; CG1506-PA; adenylate cyclase 3, isoform A; adenylate cyclase 3", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); major depressive disorder (Disease Ontology:DOID:1470); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": " (R-DME-163615); (R-DME-170660); (R-DME-170670); (R-DME-418597); (R-DME-5610787)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0016020 membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0007623 circadian rhythm;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9V9R3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VA28-1", "uniprot_id": [ { "id": "Q9VA28_DROME", "url": "https://www.uniprot.org/uniprot/Q9VA28", "type": "external" } ], "mass": 43194.0, "length": 390, "protein_name": "Nucleoside diphosphate kinase-like domain-containing protein", "gene_name": "Dmel\\CG15547", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_651833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651833", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG15547; CG15547; Dmel_CG15547", "gene_names_refseq": "CG15547; Dmel\\CG15547", "protein_names_uniprotkb": "Nucleoside diphosphate kinase-like domain-containing protein", "protein_names_refseq": "CG15547-PA; uncharacterized protein", "tax_id": 7227, "disease": "hydrocephalus (Disease Ontology:DOID:10908); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG15547)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005929 cilium", "go_biological_process": "GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0003341 cilium movement", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VA28-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VA50-1", "uniprot_id": [ { "id": "Q9VA50_DROME", "url": "https://www.uniprot.org/uniprot/Q9VA50", "type": "external" } ], "mass": 61506.0, "length": 534, "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG31013", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_733394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733394", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG31013; 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CG11908; Dmel\\CG11908; Dmel_CG11908; RADHA; RHA; anon-WO0140519.50", "gene_names_refseq": "CG11908; Dmel\\CG11908; RADHA; RHA; anon-WO0140519.50; rha", "protein_names_uniprotkb": "Rha", "protein_names_refseq": "CG11908-PA; rha-PA; rha", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11908)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VBR7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VBS4-1", "uniprot_id": [ { "id": "Q9VBS4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VBS4", "type": "external" } ], "mass": 47959.0, "length": 414, "protein_name": "CHK kinase-like domain-containing protein", "gene_name": "CT29612", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_651383", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651383", "type": "external" } ], "gene_names_uniprotkb": "CT29612; CG10553; Dmel\\CG10553; Dmel_CG10553; Dro17-1", "gene_names_refseq": "CG10553; CT29612; Dmel\\CG10553; Dro17-1", "protein_names_uniprotkb": "CHK kinase-like domain-containing protein", "protein_names_refseq": "CG10553-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10553)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0106389 ecdysteroid 22-kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VBS4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VBU2-1", "uniprot_id": [ { "id": "Q9VBU2_DROME", "url": "https://www.uniprot.org/uniprot/Q9VBU2", "type": "external" } ], "mass": 61431.0, "length": 538, "protein_name": "Serine/threonine-protein kinase RIO2", "gene_name": "RIOK2", "organism": "Fruit fly", "refseq_name": "RIO kinase 2", "refseq_ac": [ { "id": "NP_651365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651365", "type": "external" } ], "gene_names_uniprotkb": "RIOK2; CG11859; Dmel\\CG11859; Dmel_CG11859; Rio2; dRIOK2", "gene_names_refseq": "CG11859; Dmel\\CG11859; RIOK2; Rio2; dRIOK2", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIO2; 2.7.11.1; RIO kinase 2; Serine/threonine-protein kinase rio2", "protein_names_refseq": "CG11859-PA; RIO kinase 2; RIOK2-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11859)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0060252 positive regulation of glial cell proliferation;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VBU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VC31-1", "uniprot_id": [ { "id": "Q9VC31_DROME", "url": "https://www.uniprot.org/uniprot/Q9VC31", "type": "external" } ], "mass": 24187.0, "length": 213, "protein_name": "Ras-related protein Rab-1", "gene_name": "RabX4", "organism": "Fruit fly", "refseq_name": "RabX4", "refseq_ac": [ { "id": "NP_733043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733043", "type": "external" } ], "gene_names_uniprotkb": "RabX4; AAF56345; CG13638; CG31118; DmRabX4; Dmel\\CG31118; Dmel_CG31118; rabX4", "gene_names_refseq": "AAF56345; CG13638; CG31118; DmRabX4; Dmel\\CG31118; RabX4; rabX4", "protein_names_uniprotkb": "Ras-related protein Rab-1; Small GTP-binding protein rab1", "protein_names_refseq": "CG31118-PA; RabX4-PA; RabX4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31118)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Protein transport. 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CG7056; Dmel\\CG7056; Dmel_CG7056; dHHEX", "gene_names_refseq": "CG7056; Dmel\\CG7056; HHEX; dHHEX", "protein_names_uniprotkb": "Hematopoietically expressed homeobox", "protein_names_refseq": "CG7056-PA; HHEX ortholog; HHEX-PA; hematopoietically expressed homeobox", "tax_id": 7227, "disease": "candidiasis (Disease Ontology:DOID:1508); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG7056)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0009744 response to sucrose", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDF0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VDF9-1", "uniprot_id": [ { "id": "Q9VDF9_DROME", "url": "https://www.uniprot.org/uniprot/Q9VDF9", "type": "external" } ], "mass": 26241.0, "length": 229, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG12278", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650934", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650934", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG12278; 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CG4770; Dmel_CG4770", "gene_names_refseq": "CG4770; Dmel\\CG4770", "protein_names_uniprotkb": "Fatty acyl-CoA reductase; 1.2.1.84", "protein_names_refseq": "CG4770-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4770); (R-DME-9640463)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the reduction of fatty acyl-CoA to fatty alcohols., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.84", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.84", "type": "external" } ], "go_molecular_function": "GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity;GO:0102965 alcohol-forming long-chain fatty acyl-CoA reductase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0035336 long-chain fatty-acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VDS2-1", "uniprot_id": [ { "id": "Q9VDS2_DROME", "url": "https://www.uniprot.org/uniprot/Q9VDS2", "type": "external" } ], "mass": 64510.0, "length": 577, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG4465", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650847", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650847", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG4465; CG4465; Dmel_CG4465", "gene_names_refseq": "CG4465; Dmel\\CG4465", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG4465-PA; uncharacterized protein", "tax_id": 7227, "disease": "diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": " (dme:Dmel_CG4465); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0015711 organic anion transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDS2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VDT9-1", "uniprot_id": [ { "id": "Q9VDT9_DROME", "url": "https://www.uniprot.org/uniprot/Q9VDT9", "type": "external" } ], "mass": 84098.0, "length": 770, "protein_name": "Fibroblast growth factor", "gene_name": "bnl", "organism": "Fruit fly", "refseq_name": "branchless, isoform A", "refseq_ac": [ { "id": "NP_732452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_732452", "type": "external" } ], "gene_names_uniprotkb": "bnl; BNL; Bnl; Branchless; CG4608; DFGF; DmBnl; Dmel\\CG4608; Dmel_CG4608; FGF-2; FGF; dFGF; l(3)06916; l(3)neo52", "gene_names_refseq": "BNL; Bnl/FGF; Bnl; Branchless; CG4608; DFGF; DmBnl; Dmel\\CG4608; FGF-2; FGF; bnl; dFGF; l(3)06916; l(3)neo52", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "CG4608-PA; bnl-PA; branchless, isoform A; branchless; fibroblast growth factor protein; fibroblast growth factor); fibroblast growth factor", "tax_id": 7227, "disease": "lacrimoauriculodentodigital syndrome 1 (Disease Ontology:DOID:0050331); non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); developmental and epileptic encephalopathy 90 (Disease Ontology:DOID:0070381); developmental and epileptic encephalopathy 47 (Disease Ontology:DOID:0080425); lacrimoauriculodentodigital syndrome 3 (Disease Ontology:DOID:0081372); aplasia of lacrimal and salivary glands (Disease Ontology:DOID:0111549); familial isolated trichomegaly (Disease Ontology:DOID:0111566); syndactyly type 8 (Disease Ontology:DOID:0111813); prostate cancer (Disease Ontology:DOID:10283); intestinal atresia (Disease Ontology:DOID:10486); intellectual disability (Disease Ontology:DOID:1059); hypospadias (Disease Ontology:DOID:10892); prostatic hypertrophy (Disease Ontology:DOID:11132); leiomyoma (Disease Ontology:DOID:127); squamous cell carcinoma (Disease Ontology:DOID:1749); atherosclerosis (Disease Ontology:DOID:1936); ovarian cancer (Disease Ontology:DOID:2394); endometrial carcinoma (Disease Ontology:DOID:2871); severe acute respiratory syndrome (Disease Ontology:DOID:2945); cervical squamous cell carcinoma (Disease Ontology:DOID:3744); chronic kidney disease (Disease Ontology:DOID:784); ulcerative colitis (Disease Ontology:DOID:8577); prostate carcinoma in situ (Disease Ontology:DOID:8634); Crohn's disease (Disease Ontology:DOID:8778); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (R-DME-109704); (R-DME-1257604); (R-DME-1307965); (R-DME-189200); (R-DME-190322); (R-DME-190370); (R-DME-190371); (R-DME-190372); (R-DME-190373); (R-DME-190374); (R-DME-190375); (R-DME-190377); (R-DME-381426); (R-DME-5654219); (R-DME-5654221); (R-DME-5654227); (R-DME-5654228); (R-DME-5654687); (R-DME-5654688); (R-DME-5654689); (R-DME-5654693); (R-DME-5654695); (R-DME-5654699); (R-DME-5654700); (R-DME-5654704); (R-DME-5654706); (R-DME-5654710); (R-DME-5654712); (R-DME-5654719); (R-DME-5654720); (R-DME-5654726); (R-DME-5654727); (R-DME-5654732); (R-DME-5654733); (R-DME-5658623); (R-DME-5673001); (R-DME-6811558); (R-DME-8957275)", "pathway_count": 38, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 25, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008083 growth factor activity;GO:0016015 morphogen activity;GO:0005104 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0046847 filopodium assembly;GO:0030334 regulation of cell migration;GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDT9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VDU0-1", "uniprot_id": [ { "id": "Q9VDU0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VDU0", "type": "external" } ], "mass": 59584.0, "length": 539, "protein_name": "6.2.1.3; Acyl-CoA synthetase X4", "gene_name": "Acsx4", "organism": "Fruit fly", "refseq_name": "Acyl-CoA synthetase X4", "refseq_ac": [ { "id": "NP_650832", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650832", "type": "external" } ], "gene_names_uniprotkb": "Acsx4; CG11453; Dmel\\CG11453; Dmel_CG11453", "gene_names_refseq": "Acsx4; CG11453; Dmel\\CG11453", "protein_names_uniprotkb": "6.2.1.3; Acyl-CoA synthetase X4", "protein_names_refseq": "Acsx4-PA; Acyl-CoA synthetase X4; CG11453-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11453)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004467 long-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0010891 negative regulation of triglyceride storage;GO:0046949 fatty-acyl-CoA biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VDW0-1", "uniprot_id": [ { "id": "Q9VDW0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VDW0", "type": "external" } ], "mass": 60928.0, "length": 541, "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG7333", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650814", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG7333; CG7333; Dmel_CG7333", "gene_names_refseq": "CG7333; Dmel\\CG7333", "protein_names_uniprotkb": "Major facilitator superfamily (MFS) profile domain-containing protein", "protein_names_refseq": "CG7333-PB; uncharacterized protein", "tax_id": 7227, "disease": "kidney failure (Disease Ontology:DOID:1074); extrahepatic cholestasis (Disease Ontology:DOID:13619); intrahepatic cholestasis (Disease Ontology:DOID:1852); hyperuricemia (Disease Ontology:DOID:1920); acute kidney failure (Disease Ontology:DOID:3021); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG7333); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDW0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VDX6-1", "uniprot_id": [ { "id": "Q9VDX6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VDX6", "type": "external" } ], "mass": 54038.0, "length": 480, "protein_name": "Serine protease K12H4.7", "gene_name": "Dmel\\CG18493", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650803", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650803", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG18493; CG18493; Dmel_CG18493", "gene_names_refseq": "CG18493; Dmel\\CG18493", "protein_names_uniprotkb": "Serine protease K12H4.7", "protein_names_refseq": "CG18493-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18493)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0017171 serine hydrolase activity;GO:0070008 serine-type exopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VDX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VE55-1", "uniprot_id": [ { "id": "Q9VE55_DROME", "url": "https://www.uniprot.org/uniprot/Q9VE55", "type": "external" } ], "mass": 211179.0, "length": 1857, "protein_name": "Qin", "gene_name": "qin", "organism": "Fruit fly", "refseq_name": "qin", "refseq_ac": [ { "id": "NP_650735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650735", "type": "external" } ], "gene_names_uniprotkb": "qin; CG14303; CG14306; CG43726; Dmel\\CG43726; Dmel_CG43726; Qin; kumo", "gene_names_refseq": "CG14303; CG14306; CG43726; Dmel\\CG43726; Qin; kumo; qin", "protein_names_uniprotkb": "Qin", "protein_names_refseq": "CG43726-PB; kumo; qin-PB; qin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43726)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0043186 P granule", "go_biological_process": "GO:0030719 P granule organization;GO:0007283 spermatogenesis;GO:0034587 piRNA processing;GO:0140965 secondary piRNA processing;GO:0141009 transposable element silencing by piRNA-mediated mRNA destabilization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VE55-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VE92-1", "uniprot_id": [ { "id": "Q9VE92_DROME", "url": "https://www.uniprot.org/uniprot/Q9VE92", "type": "external" } ], "mass": 25544.0, "length": 224, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG7126", "organism": "Fruit fly", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dmel\\CG7126; CG7126; Dmel_CG7126", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7126)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VE92-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEA3-1", "uniprot_id": [ { "id": "Q9VEA3_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEA3", "type": "external" } ], "mass": 50950.0, "length": 475, "protein_name": "Homeobox domain-containing protein", "gene_name": "Dmel\\CG18599", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650701", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650701", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG18599; CG18599; Dmel_CG18599", "gene_names_refseq": "CG18599; Dmel\\CG18599", "protein_names_uniprotkb": "Homeobox domain-containing protein", "protein_names_refseq": "CG18599-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18599)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007417 central nervous system development;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEA4-1", "uniprot_id": [ { "id": "Q9VEA4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEA4", "type": "external" } ], "mass": 53601.0, "length": 466, "protein_name": "Trimethylguanosine synthase", "gene_name": "Tgs1", "organism": "Fruit fly", "refseq_name": "trimethylguanosine synthase 1", "refseq_ac": [ { "id": "NP_732316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_732316", "type": "external" } ], "gene_names_uniprotkb": "Tgs1; 13; CG31241; CG44890; CG8045; CT24102; DTLd; DTL; Dmel\\CG44890; Dmel_CG44890; Dtl; TGS1; dORF; dTgs1; dtl; l(3)S096713; tatl; tgs1", "gene_names_refseq": "0967/13; CG31241; CG44890; CG8045; CT24102; DTLd; DTL; Dmel\\CG44890; Dromel_CG31241_FBtr0083570_dtl_mORF; Dtl; TGS1; Tgs1; dORF; dTgs1; dtl; l(3)S096713; tatl; tgs1", "protein_names_uniprotkb": "Trimethylguanosine synthase; Cap-specific guanine-N(2) methyltransferase; Nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif", "protein_names_refseq": "CG44890-PB; Tat like; Tgs1-PB; drosophila Tat-like; lethal (3) S096713; tat-like; trimethylguanosine synthase 1 ortholog; trimethylguanosine synthase 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44890); (R-DME-400206); (R-DME-9707564)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071164 RNA cap trimethylguanosine synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0015030 Cajal body", "go_biological_process": "GO:0009452 7-methylguanosine RNA capping;GO:0036261 7-methylguanosine cap hypermethylation;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEA4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEH7-1", "uniprot_id": [ { "id": "Q9VEH7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEH7", "type": "external" } ], "mass": 13108.0, "length": 137, "protein_name": "Uncharacterized protein", "gene_name": "BcDNA:RE19820", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650639", "type": "external" } ], "gene_names_uniprotkb": "BcDNA:RE19820; CG14326; Dmel\\CG14326; Dmel_CG14326", "gene_names_refseq": "BcDNA:RE19820; CG14326; Dmel\\CG14326", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG14326-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14326)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEM6-1", "uniprot_id": [ { "id": "Q9VEM6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEM6", "type": "external" } ], "mass": 29845.0, "length": 272, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG5246", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650603", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG5246; BcDNA:LP06628; CG5246; Dmel_CG5246; SP96", "gene_names_refseq": "BcDNA:LP06628; CG5246; Dmel\\CG5246; SP96", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "CG5246-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5246)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0016485 protein processing;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEP4-1", "uniprot_id": [ { "id": "Q9VEP4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEP4", "type": "external" } ], "mass": 63924.0, "length": 594, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG5225", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650587", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG5225; CG5225; Dmel_CG5225", "gene_names_refseq": "CG5225; Dmel\\CG5225", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG5225-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5225)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEP4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEQ5-1", "uniprot_id": [ { "id": "Q9VEQ5_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEQ5", "type": "external" } ], "mass": 63336.0, "length": 553, "protein_name": "Alpha actinin 3", "gene_name": "Actn3", "organism": "Fruit fly", "refseq_name": "alpha actinin 3", "refseq_ac": [ { "id": "NP_524801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524801", "type": "external" } ], "gene_names_uniprotkb": "Actn3; CG8953; Dmel\\CG8953; Dmel_CG8953; ORF1; acta-3; actn3; dabp", "gene_names_refseq": "Actn3; CG8953; Dmel\\CG8953; ORF1; acta-3; actn3; dabp", "protein_names_uniprotkb": "Alpha actinin 3", "protein_names_refseq": "Actn3-PA; CG8953-PA; actinin 3; alpha actinin 3; alpha-actinin-like; alpha-actinin3; open reading frame 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8953)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VES4-1", "uniprot_id": [ { "id": "Q9VES4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VES4", "type": "external" } ], "mass": 56181.0, "length": 473, "protein_name": "Coiled-coil domain containing protein 114", "gene_name": "Ccdc114", "organism": "Fruit fly", "refseq_name": "Coiled-coil domain containing protein 114", "refseq_ac": [ { "id": "NP_650569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650569", "type": "external" } ], "gene_names_uniprotkb": "Ccdc114; 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CG2727; Dmel\\CG2727; Dmel_CG2727; Emp", "gene_names_refseq": "CG2727; Dmel\\CG2727; Emp; emp", "protein_names_uniprotkb": "Scavenger receptor class B member 1; SR-BI", "protein_names_refseq": "CG2727-PB; emp-PB; epithelial membrane protein, isoform B; epithelial membrane protein", "tax_id": 7227, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); morbid obesity (Disease Ontology:DOID:11981); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG2727); (R-DME-114608); (R-DME-1236973); (R-DME-434313); (R-DME-6798695)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity", "go_cellular_component": "GO:0005901 caveola;GO:0016020 membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006898 receptor-mediated endocytosis;GO:0035159 regulation of tube length, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W0X0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VMR4-1", "uniprot_id": [ { "id": "Q9VMR4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VMR4", "type": "external" } ], "mass": 192252.0, "length": 1761, "protein_name": "No mechanoreceptor potential C, isoform H", "gene_name": "nompC", "organism": "Fruit fly", "refseq_name": "no mechanoreceptor potential C, isoform H", "refseq_ac": [ { "id": "NP_523483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523483", "type": "external" } ], "gene_names_uniprotkb": "nompC; CG11020; CG17468; CT30855; DmNompC; Dmel\\CG11020; Dmel_CG11020; NOMPC; NompC; Nompc; ORE-13; TRPN1; TRPN; jf24; l(2)25Dc; l(2)jf24; nompc; nomp", "gene_names_refseq": "CG11020; CG17468; CT30855; DmNompC; Dmel\\CG11020; NOMPC; NompC; Nompc; ORE-13; TRPN1; TRPN; jf24; l(2)25Dc; l(2)jf24; nompC; nompc; nomp", "protein_names_uniprotkb": "No mechanoreceptor potential C, isoform H", "protein_names_refseq": "CG11020-PH; No Mechano-receptor potential C; No mechanoreceptor potential C; TRPN; lethal(2)25Dc; no mechanoreceptor potential C, isoform H; nompC-PH", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11020); (R-DME-8951664); (R-DME-983168)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9NGR8", "ec_number_list": [], "go_molecular_function": "GO:0005216 monoatomic ion channel activity;GO:0005262 calcium channel activity;GO:0005261 monoatomic cation channel activity;GO:0030506 ankyrin binding;GO:0008381 mechanosensitive monoatomic ion channel activity", "go_cellular_component": "GO:0034703 cation channel complex;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0001964 startle response;GO:0050954 sensory perception of mechanical stimulus;GO:0007638 mechanosensory behavior;GO:0050976 detection of mechanical stimulus involved in sensory perception of touch;GO:0050975 sensory perception of touch", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VMR4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W0S2-1", "uniprot_id": [ { "id": "Q9W0S2_DROME", "url": "https://www.uniprot.org/uniprot/Q9W0S2", "type": "external" } ], "mass": 384010.0, "length": 3519, "protein_name": "Rho guanine nucleotide exchange factor 3, isoform L", "gene_name": "RhoGEF3", "organism": "Fruit fly", "refseq_name": "Rho guanine nucleotide exchange factor 3, isoform L", "refseq_ac": [ { "id": "NP_612024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612024", "type": "external" } ], "gene_names_uniprotkb": "RhoGEF3; CG1225; CG13881; CG13882; CG13883; CG42377; CG42378; CG43976; Dmel\\CG43976; Dmel_CG43976; DrhoGEF3; RhoGEF; rhoGEF3", "gene_names_refseq": "CG1225; CG13881; CG13882; CG13883; CG42377; CG42378; CG43976; Dmel\\CG43976; DrhoGEF3; RhoGEF3; RhoGEF; rhoGEF3", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 3, isoform L", "protein_names_refseq": "CG43976-PL; Rho guanine nucleotide exchange factor 3, isoform L; RhoGEF3-PL", "tax_id": 7227, "disease": "developmental and epileptic encephalopathy 8 (Disease Ontology:DOID:0080215)", "pathway": " (dme:Dmel_CG43976); (R-DME-193648); (R-DME-416482); (R-DME-9013148); (R-DME-9013149); (R-DME-9013406); (R-DME-977443)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035023 regulation of Rho protein signal transduction;GO:0035011 melanotic encapsulation of foreign target;GO:0030036 actin cytoskeleton organization;GO:0009611 response to wounding;GO:0042060 wound healing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W0S2-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W2Z8-1", "uniprot_id": [ { "id": "Q9W2Z8_DROME", "url": "https://www.uniprot.org/uniprot/Q9W2Z8", "type": "external" } ], "mass": 63238.0, "length": 587, "protein_name": "Keratin, type I cytoskeletal 9", "gene_name": "Dmel\\CG15252", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_572595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572595", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG15252; CG15252; Dmel_CG15252", "gene_names_refseq": "CG15252; Dmel\\CG15252", "protein_names_uniprotkb": "Keratin, type I cytoskeletal 9", "protein_names_refseq": "CG15252-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15252)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W2Z8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VW85-1", "uniprot_id": [ { "id": "Q9VW85_DROME", "url": "https://www.uniprot.org/uniprot/Q9VW85", "type": "external" } ], "mass": 177395.0, "length": 1661, "protein_name": "DH domain-containing protein", "gene_name": "CG13811; CG13812; CG7323", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": [ { "id": "NP_649182", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649182", "type": "external" } ], "gene_names_uniprotkb": "CG13811; CG13812; CG7323; CG13811; CG13812; CG32223; CG42348; CG42674; CG7323; Dmel\\CG42674; Dmel_CG42674", "gene_names_refseq": "CG13811; CG13812; CG32223; CG42348; CG42674; CG7323; Dmel\\CG42674", "protein_names_uniprotkb": "DH domain-containing protein", "protein_names_refseq": "CG42674-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "Charcot-Marie-Tooth disease recessive intermediate C (Disease Ontology:DOID:0110198); autosomal recessive distal hereditary motor neuronopathy 4 (Disease Ontology:DOID:0111213); cystic fibrosis (Disease Ontology:DOID:1485)", "pathway": " (dme:Dmel_CG42674); (R-DME-193648); (R-DME-416482); (R-DME-8980692)", "pathway_count": 4, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0035025 positive regulation of Rho protein signal transduction;GO:0007480 imaginal disc-derived leg morphogenesis;GO:0043542 endothelial cell migration", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VW85-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JG15-1", "uniprot_id": [ { "id": "X2JG15_DROME", "url": "https://www.uniprot.org/uniprot/X2JG15", "type": "external" } ], "mass": 224472.0, "length": 1998, "protein_name": "Lipid droplet defective, isoform E", "gene_name": "ldd", "organism": "Fruit fly", "refseq_name": "lipid droplet defective, isoform E", "refseq_ac": [ { "id": "NP_001285513", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285513", "type": "external" } ], "gene_names_uniprotkb": "ldd; BcDNA:AT04622; CG1819; CG32516; CG34120; DmCG1819; Dmel\\CG34120; Dmel_CG34120", "gene_names_refseq": "BcDNA:AT04622; CG1819; CG32516; CG34120; DmCG1819; Dmel\\CG34120; ldd", "protein_names_uniprotkb": "Lipid droplet defective, isoform E", "protein_names_refseq": "CG34120-PE; ldd-PE; lipid droplet defective, isoform E", "tax_id": 7227, "disease": "Stargardt disease (Disease Ontology:DOID:0050817); autosomal recessive congenital ichthyosis 1 (Disease Ontology:DOID:0060656); autosomal recessive congenital ichthyosis 4A (Disease Ontology:DOID:0060712); autosomal recessive congenital ichthyosis 4B (Disease Ontology:DOID:0060713); retinitis pigmentosa 91 (Disease Ontology:DOID:0061106); age related macular degeneration 2 (Disease Ontology:DOID:0110015); retinitis pigmentosa 19 (Disease Ontology:DOID:0110354); cone-rod dystrophy 3 (Disease Ontology:DOID:0111013); Alzheimer's disease 9 (Disease Ontology:DOID:0111364); retinitis pigmentosa (Disease Ontology:DOID:10584); premature menopause (Disease Ontology:DOID:10787); membranous glomerulonephritis (Disease Ontology:DOID:10976); familial hyperlipidemia (Disease Ontology:DOID:1168); extrahepatic cholestasis (Disease Ontology:DOID:13619); Tangier disease (Disease Ontology:DOID:1388); alcohol use disorder (Disease Ontology:DOID:1574); gastric adenocarcinoma (Disease Ontology:DOID:3717); macular degeneration (Disease Ontology:DOID:4448); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); retinal degeneration (Disease Ontology:DOID:8466); fundus dystrophy (Disease Ontology:DOID:8501); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG34120); (R-DME-1369062); (R-DME-6798695)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity;GO:0005319 lipid transporter activity;GO:0042626 ATPase-coupled transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JG15-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JAX8-1", "uniprot_id": [ { "id": "X2JAX8_DROME", "url": "https://www.uniprot.org/uniprot/X2JAX8", "type": "external" } ], "mass": 150431.0, "length": 1330, "protein_name": "Nostrin, isoform H", "gene_name": "Nost", "organism": "Fruit fly", "refseq_name": "nostrin, isoform H", "refseq_ac": [ { "id": "NP_001285029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285029", "type": "external" } ], "gene_names_uniprotkb": "Nost; CG15364; CG33224; CG4040; CG42388; Dmel\\CG42388; Dmel_CG42388; NOSTRIN; nost", "gene_names_refseq": "CG15364; CG33224; CG4040; CG42388; Dmel\\CG42388; NOSTRIN; Nost; nost", "protein_names_uniprotkb": "Nostrin, isoform H", "protein_names_refseq": "CG42388-PH; Nost-PH; nostrin, isoform H; nostrin", "tax_id": 7227, "disease": "stroke (Disease Ontology:DOID:0051061)", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005768 endosome;GO:0005856 cytoskeleton;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0097320 plasma membrane tubulation;GO:0030708 germarium-derived female germ-line cyst encapsulation;GO:1903391 regulation of adherens junction organization;GO:0035317 imaginal disc-derived wing hair organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JAX8-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VMJ6-1", "uniprot_id": [ { "id": "Q9VMJ6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VMJ6", "type": "external" } ], "mass": 35414.0, "length": 314, "protein_name": "Tetraspanin 26A, isoform B", "gene_name": "Tsp26A", "organism": "Fruit fly", "refseq_name": "tetraspanin 26A, isoform B", "refseq_ac": [ { "id": "NP_001097093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097093", "type": "external" } ], "gene_names_uniprotkb": "Tsp26A; CG9093; Dm.Tsp26A; Dmel\\CG9093; Dmel_CG9093; tsp26A", "gene_names_refseq": "CG9093; Dm.Tsp26A; Dmel\\CG9093; Tsp26A; tsp26A", "protein_names_uniprotkb": "Tetraspanin 26A, isoform B", "protein_names_refseq": "CG9093-PB; Tsp26A-PB; tetraspanin 26A, isoform B", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG9093); (R-DME-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0045747 positive regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VMJ6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VRR0-1", "uniprot_id": [ { "id": "Q9VRR0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VRR0", "type": "external" } ], "mass": 80336.0, "length": 706, "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG10486", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_647998", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647998", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10486; CG10486; Dmel_CG10486", "gene_names_refseq": "CG10486; Dmel\\CG10486", "protein_names_uniprotkb": "Major facilitator superfamily (MFS) profile domain-containing protein", "protein_names_refseq": "CG10486-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "kidney failure (Disease Ontology:DOID:1074); extrahepatic cholestasis (Disease Ontology:DOID:13619); intrahepatic cholestasis (Disease Ontology:DOID:1852); hyperuricemia (Disease Ontology:DOID:1920); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG10486); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VRR0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JEI9-1", "uniprot_id": [ { "id": "X2JEI9_DROME", "url": "https://www.uniprot.org/uniprot/X2JEI9", "type": "external" } ], "mass": 232296.0, "length": 2206, "protein_name": "Rho GTPase activating protein at 19D, isoform D", "gene_name": "RhoGAP19D", "organism": "Fruit fly", "refseq_name": "Rho GTPase activating protein at 19D, isoform D", "refseq_ac": [ { "id": "NP_001285496", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285496", "type": "external" } ], "gene_names_uniprotkb": "RhoGAP19D; 1412; CG1412; Dmel\\CG1412; Dmel_CG1412", "gene_names_refseq": "1412; CG1412; Dmel\\CG1412; RhoGAP19D", "protein_names_uniprotkb": "Rho GTPase activating protein at 19D, isoform D", "protein_names_refseq": "CG1412-PD; Rho GTPase activating protein at 19D, isoform D; RhoGAP19D-PD", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1412)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007266 Rho protein signal transduction;GO:0007480 imaginal disc-derived leg morphogenesis;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JEI9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VPV8-1", "uniprot_id": [ { "id": "Q9VPV8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VPV8", "type": "external" } ], "mass": 146877.0, "length": 1319, "protein_name": "IA-2 protein tyrosine phosphatase, isoform C", "gene_name": "IA-2", "organism": "Fruit fly", "refseq_name": "IA-2 protein tyrosine phosphatase, isoform C", "refseq_ac": [ { "id": "NP_608562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608562", "type": "external" } ], "gene_names_uniprotkb": "IA-2; 1A2; CG11344; CG31795; CG4355; Dmel\\CG31795; Dmel_CG31795; IA2; anon-WO0153538.69; ia-2; ia2", "gene_names_refseq": "CG11344; CG31795; CG4355; Dmel\\CG31795; IA-2; IA2; R-PTPX/1A2; anon-WO0153538.69; ia-2; ia2", "protein_names_uniprotkb": "IA-2 protein tyrosine phosphatase, isoform C", "protein_names_refseq": "CG31795-PC; IA-2 ortholog; IA-2 protein tyrosine phosphatase, isoform C; IA-2-PC; ia2", "tax_id": 7227, "disease": "prediabetes syndrome (Disease Ontology:DOID:11716); Parkinson's disease (Disease Ontology:DOID:14330); diabetes mellitus (Disease Ontology:DOID:9351); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG31795); (R-DME-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030141 secretory granule;GO:0045202 synapse;GO:0030658 transport vesicle membrane", "go_biological_process": "GO:0048565 digestive tract development;GO:0048666 neuron development;GO:0051046 regulation of secretion;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VPV8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VQL0-1", "uniprot_id": [ { "id": "Q9VQL0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VQL0", "type": "external" } ], "mass": 103970.0, "length": 876, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG17258", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_608742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608742", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG17258; CG17258; Dmel_CG17258", "gene_names_refseq": "CG17258; Dmel\\CG17258", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG17258-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17258)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQL0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VLG5-1", "uniprot_id": [ { "id": "Q9VLG5_DROME", "url": "https://www.uniprot.org/uniprot/Q9VLG5", "type": "external" } ], "mass": 78959.0, "length": 678, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9525; gi7297470", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_609260", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609260", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG9525; gi7297470; CG9525; Dmel\\CG9525; Dmel_CG9525; gi7297470", "gene_names_refseq": "CG9525; Dmel\\CG9525; gi7297470", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG9525-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9525)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007618 mating", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VLG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VQF4-1", "uniprot_id": [ { "id": "Q9VQF4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VQF4", "type": "external" } ], "mass": 48561.0, "length": 448, "protein_name": "Phosphoglycerate kinase", "gene_name": "Pgk2", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_608704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608704", "type": "external" } ], "gene_names_uniprotkb": "Pgk2; CG9961; Dmel\\CG9961; Dmel_CG9961", "gene_names_refseq": "CG9961; Dmel\\CG9961", "protein_names_uniprotkb": "Phosphoglycerate kinase; 2.7.2.3", "protein_names_refseq": "CG9961-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "phosphoglycerate kinase 1 deficiency (Disease Ontology:DOID:0111933); cancer (Disease Ontology:DOID:162); hemolytic anemia (Disease Ontology:DOID:583)", "pathway": " (dme:Dmel_CG9961); (R-DME-70171); (R-DME-70263)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" } ], "go_molecular_function": "GO:0004618 phosphoglycerate kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043531 ADP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006096 glycolytic process;GO:0006094 gluconeogenesis;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQF4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VT33-1", "uniprot_id": [ { "id": "Q9VT33_DROME", "url": "https://www.uniprot.org/uniprot/Q9VT33", "type": "external" } ], "mass": 42696.0, "length": 388, "protein_name": "ribose-phosphate diphosphokinase", "gene_name": "Prps", "organism": "Fruit fly", "refseq_name": "phosphoribosyl pyrophosphate synthetase, isoform B", "refseq_ac": [ { "id": "NP_729528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729528", "type": "external" } ], "gene_names_uniprotkb": "Prps; CG6767; Dmel\\CG6767; Dmel_CG6767; PRPS", "gene_names_refseq": "CG6767; Dmel\\CG6767; PRPS; Prps", "protein_names_uniprotkb": "ribose-phosphate diphosphokinase; 2.7.6.1", "protein_names_refseq": "CG6767-PB; Prps-PB; phosphoribosyl pyrophosphate synthetase, isoform B", "tax_id": 7227, "disease": "Arts syndrome (Disease Ontology:DOID:0050647); Charcot-Marie-Tooth disease X-linked recessive 5 (Disease Ontology:DOID:0110210); phosphoribosylpyrophosphate synthetase superactivity (Disease Ontology:DOID:0111260); X-linked deafness 1 (Disease Ontology:DOID:0111739); retinitis pigmentosa (Disease Ontology:DOID:10584); gout (Disease Ontology:DOID:13189)", "pathway": " (dme:Dmel_CG6767)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.6.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.6.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0004749 ribose phosphate diphosphokinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0009156 ribonucleoside monophosphate biosynthetic process;GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process;GO:0009165 nucleotide biosynthetic process;GO:0042048 olfactory behavior;GO:0006164 purine nucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VT33-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2J8X8-1", "uniprot_id": [ { "id": "X2J8X8_DROME", "url": "https://www.uniprot.org/uniprot/X2J8X8", "type": "external" } ], "mass": 42839.0, "length": 396, "protein_name": "Defective proboscis extension response 6, isoform F", "gene_name": "dpr6", "organism": "Fruit fly", "refseq_name": "defective proboscis extension response 6, isoform F", "refseq_ac": [ { "id": "NP_001287018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287018", "type": "external" } ], "gene_names_uniprotkb": "dpr6; BcDNA:LD13525; CG14162; Dmel\\CG14162; Dmel_CG14162; Dpr-6; Dpr6", "gene_names_refseq": "BcDNA:LD13525; CG14162; Dmel\\CG14162; Dpr-6; Dpr6; dpr6", "protein_names_uniprotkb": "Defective proboscis extension response 6, isoform F", "protein_names_refseq": "CG14162-PF; defective proboscis extension response 6, isoform F; defective proboscis response 6; dpr6-PF", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14162)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;26687361", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0032589 neuron projection membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0050808 synapse organization;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "X2J8X8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.1000000001000.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VT34-1", "uniprot_id": [ { "id": "Q9VT34_DROME", "url": "https://www.uniprot.org/uniprot/Q9VT34", "type": "external" } ], "mass": 99032.0, "length": 889, "protein_name": "SANT and BTB domain-containing protein", "gene_name": "Dmel\\CG6761", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_648346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648346", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG6761; CG6761; Dmel_CG6761", "gene_names_refseq": "CG6761; Dmel\\CG6761", "protein_names_uniprotkb": "SANT and BTB domain-containing protein", "protein_names_refseq": "CG6761-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6761)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VT34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VU19-1", "uniprot_id": [ { "id": "Q9VU19_DROME", "url": "https://www.uniprot.org/uniprot/Q9VU19", "type": "external" } ], "mass": 40226.0, "length": 384, "protein_name": "WW domain binding protein 2, isoform E", "gene_name": "Wbp2", "organism": "Fruit fly", "refseq_name": "WW domain binding protein 2, isoform E", "refseq_ac": [ { "id": "NP_648607", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648607", "type": "external" } ], "gene_names_uniprotkb": "Wbp2; CG11009; Dmel\\CG11009; Dmel_CG11009; WWBP; wbp2", "gene_names_refseq": "CG11009; Dmel\\CG11009; WWBP; Wbp2; wbp2", "protein_names_uniprotkb": "WW domain binding protein 2, isoform E", "protein_names_refseq": "CG11009-PE; WW domain binding protein 2, isoform E; Wbp2 ortholog; Wbp2-PE", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 107 (Disease Ontology:DOID:0080262)", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0045572 positive regulation of imaginal disc growth", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VU19-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VZH5-1", "uniprot_id": [ { "id": "Q9VZH5_DROME", "url": "https://www.uniprot.org/uniprot/Q9VZH5", "type": "external" } ], "mass": 56182.0, "length": 511, "protein_name": "CLIP domain-containing serine protease", "gene_name": "Dmel\\CG1299; 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CG7955; DmCG7955; Dmel\\CG7955; Dmel_CG7955; dABCB7", "gene_names_refseq": "ABCB7; CG7955; DmCG7955; Dmel\\CG7955; dABCB7", "protein_names_uniprotkb": "Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial", "protein_names_refseq": "ABCB7-PA; ATP binding cassette subfamily B member 7, isoform A; CG7955-PA", "tax_id": 7227, "disease": "X-linked sideroblastic anemia with ataxia (Disease Ontology:DOID:0050554); sideroblastic anemia (Disease Ontology:DOID:8955)", "pathway": " (dme:Dmel_CG7955); (R-DME-1369007)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0140481 ABC-type iron-sulfur cluster transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0140466 iron-sulfur cluster export from the mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W0C5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VX51-1", "uniprot_id": [ { "id": "Q9VX51_DROME", "url": "https://www.uniprot.org/uniprot/Q9VX51", "type": "external" } ], "mass": 75748.0, "length": 655, "protein_name": "3.2.1.-; 3.2.1.96; Endo-beta-N-acetylglucosaminidase, isoform A", "gene_name": "ENGase", "organism": "Fruit fly", "refseq_name": "Endo-beta-N-acetylglucosaminidase, isoform A", "refseq_ac": [ { "id": "NP_573215", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573215", "type": "external" } ], "gene_names_uniprotkb": "ENGase; CG5613; Dmel\\CG5613; Dmel_CG5613", "gene_names_refseq": "CG5613; Dmel\\CG5613; ENGase", "protein_names_uniprotkb": "3.2.1.-; 3.2.1.96; Endo-beta-N-acetylglucosaminidase, isoform A", "protein_names_refseq": "CG5613-PA; ENGase-PA; Endo-beta-N-acetylglucosaminidase, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5613); (R-DME-532668)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.2.1.96", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.96", "type": "external" } ], "go_molecular_function": "GO:0017022 myosin binding;GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006491 N-glycan processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VX51-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VXX6-1", "uniprot_id": [ { "id": "Q9VXX6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VXX6", "type": "external" } ], "mass": 169357.0, "length": 1605, "protein_name": "Uncharacterized protein", "gene_name": "CG15028; Dmel\\CG43737", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001096985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096985", "type": "external" } ], "gene_names_uniprotkb": "CG15028; Dmel\\CG43737; CG15028; CG15029; CG43737; Dm_X:77844; Dmel\\CG43737; Dmel_CG43737", "gene_names_refseq": "CG15028; CG15029; CG43737; Dm_X:77844; Dmel\\CG43737", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG43737-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43737)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VXX6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W0H1-1", "uniprot_id": [ { "id": "Q9W0H1_DROME", "url": "https://www.uniprot.org/uniprot/Q9W0H1", "type": "external" } ], "mass": 26170.0, "length": 242, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9184", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_728593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728593", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG9184; CG9184; Dmel_CG9184", "gene_names_refseq": "CG9184; Dmel\\CG9184", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG9184-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9184)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W0H1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JAD3-1", "uniprot_id": [ { "id": "X2JAD3_DROME", "url": "https://www.uniprot.org/uniprot/X2JAD3", "type": "external" } ], "mass": 35604.0, "length": 308, "protein_name": "glucose-6-phosphate 1-epimerase", "gene_name": "BG:DS00797.2; Dmel\\CG9008", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": [ { "id": "NP_001285908", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285908", "type": "external" } ], "gene_names_uniprotkb": "BG:DS00797.2; Dmel\\CG9008; BG:DS00797.2; CG9008; Dmel\\CG9008; Dmel_CG9008", "gene_names_refseq": "BG:DS00797.2; CG9008; Dmel\\CG9008", "protein_names_uniprotkb": "glucose-6-phosphate 1-epimerase; 5.1.3.15", "protein_names_refseq": "CG9008-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9008)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.1.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.3", "type": "external" }, { "id": "5.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.15", "type": "external" } ], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0004034 aldose 1-epimerase activity;GO:0047938 glucose-6-phosphate 1-epimerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0051607 defense response to virus;GO:0006012 galactose metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JAD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VF56-1", "uniprot_id": [ { "id": "Q9VF56_DROME", "url": "https://www.uniprot.org/uniprot/Q9VF56", "type": "external" } ], "mass": 248996.0, "length": 2183, "protein_name": "Activating signal cointegrator 1 complex subunit 3", "gene_name": "obe", "organism": "Fruit fly", "refseq_name": "obelus", "refseq_ac": [ { "id": "NP_650472", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650472", "type": "external" } ], "gene_names_uniprotkb": "obe; CG5205; Dmel\\CG5205; Dmel_CG5205; cg5205", "gene_names_refseq": "CG5205; Dmel\\CG5205; cg5205; obe", "protein_names_uniprotkb": "Activating signal cointegrator 1 complex subunit 3; 5.6.2.4", "protein_names_refseq": "CG5205-PA; obe-PA; obelus", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder (Disease Ontology:DOID:0060308)", "pathway": " (dme:Dmel_CG5205); (R-DME-9954716)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" }, { "id": "5.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0030532 small nuclear ribonucleoprotein complex;GO:0005682 U5 snRNP", "go_biological_process": "GO:0006281 DNA repair;GO:0000398 mRNA splicing, via spliceosome;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VF56-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VFG2-1", "uniprot_id": [ { "id": "Q9VFG2_DROME", "url": "https://www.uniprot.org/uniprot/Q9VFG2", "type": "external" } ], "mass": 62520.0, "length": 556, "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG14855", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650390", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG14855; 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CG9616; Dmel_CG9616", "gene_names_refseq": "CG9616; Dmel\\CG9616", "protein_names_uniprotkb": "Serine protease gd N-terminal domain-containing protein", "protein_names_refseq": "CG9616-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9616)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VFL7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VFQ4-1", "uniprot_id": [ { "id": "Q9VFQ4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VFQ4", "type": "external" } ], "mass": 24045.0, "length": 206, "protein_name": "EF-hand domain-containing protein", "gene_name": "Dmel\\CG14362", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650320", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG14362; 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CG14374; Dmel_CG14374", "gene_names_refseq": "CG14374; Dmel\\CG14374", "protein_names_uniprotkb": "Cuticle protein 16.5", "protein_names_refseq": "CG14374-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14374)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VFV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VFZ4-1", "uniprot_id": [ { "id": "Q9VFZ4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VFZ4", "type": "external" } ], "mass": 54620.0, "length": 486, "protein_name": "Methanethiol oxidase", "gene_name": "Dmel\\CG7966", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650256", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG7966; CG7966; Dmel_CG7966", "gene_names_refseq": "CG7966; Dmel\\CG7966", "protein_names_uniprotkb": "Methanethiol oxidase", "protein_names_refseq": "CG7966-PA; uncharacterized protein", "tax_id": 7227, "disease": "glaucoma (Disease Ontology:DOID:1686)", "pathway": " (dme:Dmel_CG7966)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008430 selenium binding;GO:0018549 methanethiol oxidase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VFZ4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VGA8-1", "uniprot_id": [ { "id": "Q9VGA8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VGA8", "type": "external" } ], "mass": 63663.0, "length": 588, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG4066", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_650174", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650174", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG4066; CG4066; Dmel_CG4066", "gene_names_refseq": "CG4066; Dmel\\CG4066", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG4066-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4066)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042600 egg chorion", "go_biological_process": "GO:0007304 chorion-containing eggshell formation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VGA8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VGW0-1", "uniprot_id": [ { "id": "Q9VGW0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VGW0", "type": "external" } ], "mass": 29866.0, "length": 269, "protein_name": "Histone-lysine N-methyltransferase SETMAR", "gene_name": "Dmel\\CG4565", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001097743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097743", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG4565; CG4565; Dmel_CG4565", "gene_names_refseq": "CG4565; Dmel\\CG4565", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase SETMAR; 2.1.1.357", "protein_names_refseq": "CG4565-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4565)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046975 histone H3K36 methyltransferase activity;GO:0140954 histone H3K36 dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VGW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VH33-1", "uniprot_id": [ { "id": "Q9VH33_DROME", "url": "https://www.uniprot.org/uniprot/Q9VH33", "type": "external" } ], "mass": 18535.0, "length": 168, "protein_name": "Niemann-Pick type C-2e", "gene_name": "Npc2e", "organism": "Fruit fly", "refseq_name": "Niemann-Pick type C-2e", "refseq_ac": [ { "id": "NP_731439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_731439", "type": "external" } ], "gene_names_uniprotkb": "Npc2e; CG31410; CG3928; Dmel\\CG31410; Dmel_CG31410; npc2e", "gene_names_refseq": "CG31410; CG3928; Dmel\\CG31410; Npc2e; npc2e", "protein_names_uniprotkb": "Niemann-Pick type C-2e", "protein_names_refseq": "CG31410-PB; Niemann-Pick type C-2e; Npc2e-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31410)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042834 peptidoglycan binding;GO:0001530 lipopolysaccharide binding;GO:0032934 sterol binding;GO:0070891 lipoteichoic acid binding;GO:0030882 lipid antigen binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:1900426 positive regulation of defense response to bacterium;GO:0015918 sterol transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VH33-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VH46-1", "uniprot_id": [ { "id": "Q9VH46_DROME", "url": "https://www.uniprot.org/uniprot/Q9VH46", "type": "external" } ], "mass": 71572.0, "length": 640, "protein_name": "Serpin 85F", "gene_name": "Spn85F", "organism": "Fruit fly", "refseq_name": "serpin 85F", "refseq_ac": [ { "id": "NP_649965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649965", "type": "external" } ], "gene_names_uniprotkb": "Spn85F; CG12807; Dmel\\CG12807; Dmel_CG12807", "gene_names_refseq": "CG12807; Dmel\\CG12807; Spn85F", "protein_names_uniprotkb": "Serpin 85F", "protein_names_refseq": "CG12807-PA; Spn85F-PA; serpin 85F", "tax_id": 7227, "disease": "disease by infectious agent (Disease Ontology:DOID:0050117); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); corticosteroid-binding globulin deficiency (Disease Ontology:DOID:0090030); osteogenesis imperfecta type 6 (Disease Ontology:DOID:0110350); heparin cofactor II deficiency (Disease Ontology:DOID:0111901); retinitis pigmentosa (Disease Ontology:DOID:10584); Alzheimer's disease (Disease Ontology:DOID:10652); kidney failure (Disease Ontology:DOID:1074); anogenital venereal wart (Disease Ontology:DOID:11168); corneal neovascularization (Disease Ontology:DOID:11382); sciatic neuropathy (Disease Ontology:DOID:11446); leukostasis (Disease Ontology:DOID:12986); uveitis (Disease Ontology:DOID:13141); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); venous tributary occlusion of retina (Disease Ontology:DOID:13514); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); toxic shock syndrome (Disease Ontology:DOID:14115); Parkinson's disease (Disease Ontology:DOID:14330); hypothyroidism (Disease Ontology:DOID:1459); retinal vein occlusion (Disease Ontology:DOID:1727); nephroblastoma (Disease Ontology:DOID:2154); transient cerebral ischemia (Disease Ontology:DOID:224); endometriosis (Disease Ontology:DOID:289); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); osteosarcoma (Disease Ontology:DOID:3347); lung non-small cell carcinoma (Disease Ontology:DOID:3908); macular degeneration (Disease Ontology:DOID:4448); macular retinal edema (Disease Ontology:DOID:4449); brain edema (Disease Ontology:DOID:4724); melioidosis (Disease Ontology:DOID:5052); ovarian hyperstimulation syndrome (Disease Ontology:DOID:5425); hepatocellular carcinoma (Disease Ontology:DOID:684); retinoblastoma (Disease Ontology:DOID:768); hyperthyroidism (Disease Ontology:DOID:7998); retinal degeneration (Disease Ontology:DOID:8466); chronic fatigue syndrome (Disease Ontology:DOID:8544); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352); neovascular inflammatory vitreoretinopathy (Disease Ontology:DOID:9719); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG12807); (R-DME-114608); (R-DME-1650814); (R-DME-381426); (R-DME-6798695); (R-DME-8939242); (R-DME-8957275); (R-DME-9855719); (R-DME-9948001)", "pathway_count": 9, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 42, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0050776 regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VH46-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VH85-1", "uniprot_id": [ { "id": "Q9VH85_DROME", "url": "https://www.uniprot.org/uniprot/Q9VH85", "type": "external" } ], "mass": 102837.0, "length": 939, "protein_name": "Sidestep VII, isoform A; Sidestep VII, isoform B", "gene_name": "side-VII", "organism": "Fruit fly", "refseq_name": "sidestep VII, isoform B", "refseq_ac": [ { "id": "NP_001262432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262432", "type": "external" } ], "gene_names_uniprotkb": "side-VII; 12950; CG12950; CT32101; Dmel\\CG12950; Dmel_CG12950", "gene_names_refseq": "12950; CG12950; CT32101; Dmel\\CG12950; side-VII", "protein_names_uniprotkb": "Sidestep VII, isoform A; Sidestep VII, isoform B", "protein_names_refseq": "CG12950-PB; side-VII-PB; sidestep VII, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12950)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8T0P8", "ec_number_list": [], "go_molecular_function": "GO:0004895 cell adhesion receptor activity", "go_cellular_component": "GO:0042734 presynaptic membrane", "go_biological_process": "GO:0007416 synapse assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VH85-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VHL4-1", "uniprot_id": [ { "id": "Q9VHL4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VHL4", "type": "external" } ], "mass": 70338.0, "length": 605, "protein_name": "Ionotropic receptor 85a", "gene_name": "Ir85a", "organism": "Fruit fly", "refseq_name": "ionotropic receptor 85a", "refseq_ac": [ { "id": "NP_649833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649833", "type": "external" } ], "gene_names_uniprotkb": "Ir85a; 85a; CG11775; CT32618; DmelIR85a; Dmel\\CG11775; Dmel_CG11775; IR85a", "gene_names_refseq": "85a; CG11775; CT32618; DmelIR85a; Dmel\\CG11775; IR85a; Ir85a", "protein_names_uniprotkb": "Ionotropic receptor 85a", "protein_names_refseq": "CG11775-PA; Ir85a-PA; ionotropic receptor 85a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11775)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0009593 detection of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VHZ8-1", "uniprot_id": [ { "id": "Q9VHZ8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VHZ8", "type": "external" } ], "mass": 40145.0, "length": 358, "protein_name": "Arrestin-like N-terminal domain-containing protein", "gene_name": "Dmel\\CG18268", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_649739", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649739", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG18268; CG18268; Dmel_CG18268", "gene_names_refseq": "CG18268; Dmel\\CG18268", "protein_names_uniprotkb": "Arrestin-like N-terminal domain-containing protein", "protein_names_refseq": "CG18268-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18268)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VI72-1", "uniprot_id": [ { "id": "Q9VI72_DROME", "url": "https://www.uniprot.org/uniprot/Q9VI72", "type": "external" } ], "mass": 103283.0, "length": 901, "protein_name": "Spindle assembly abnormal 4", "gene_name": "Sas-4", "organism": "Fruit fly", "refseq_name": "spindle assembly abnormal 4", "refseq_ac": [ { "id": "NP_649701", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649701", "type": "external" } ], "gene_names_uniprotkb": "Sas-4; CENPJ; CG10061; CPAP; D-Sas4; D-sas4; DSAS-4; DSas-4; DSas4; DmSas4; Dmel\\CG10061; Dmel_CG10061; Dsas-4; Dsas4; SAS-4; SAS4; Sas4; d-SAS-4; dCPAP; dsas-4; l(3)S2214; l(3)s2214; sas-4; sas4", "gene_names_refseq": "CENPJ; CG10061; CPAP; D-Sas4; D-sas4; DSAS-4; DSas-4; DSas4; DmSas4; Dmel\\CG10061; Dsas-4; Dsas4; SAS-4; SAS4; Sas-4; Sas4; d-SAS-4; dCPAP; dsas-4; l(3)S2214; l(3)s2214; sas-4; sas4", "protein_names_uniprotkb": "Spindle assembly abnormal 4", "protein_names_refseq": "CG10061-PA; DSas-4; Sas-4-PA; drosophila Sas-4; spindle assembly abnormal 4 orthologue; spindle assembly abnormal 4 ortholog; spindle assembly abnormal 4", "tax_id": 7227, "disease": "Seckel syndrome (Disease Ontology:DOID:0050569); Seckel syndrome 4 (Disease Ontology:DOID:0070010); primary autosomal recessive microcephaly 6 (Disease Ontology:DOID:0070290); autosomal recessive primary microcephaly (Disease Ontology:DOID:0070296); microcephaly (Disease Ontology:DOID:10907)", "pathway": " (dme:Dmel_CG10061)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;24052813;25589440;26109356;26109357;28604694", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0015631 tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005814 centriole;GO:0000242 pericentriolar material", "go_biological_process": "GO:0046785 microtubule polymerization;GO:1905793 protein localization to pericentriolar material;GO:0060271 cilium assembly;GO:0007140 male meiotic nuclear division;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VI72-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIA4-1", "uniprot_id": [ { "id": "Q9VIA4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIA4", "type": "external" } ], "mass": 112475.0, "length": 965, "protein_name": "MstProx", "gene_name": "MstProx", "organism": "Fruit fly", "refseq_name": "MstProx", "refseq_ac": [ { "id": "NP_649719", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649719", "type": "external" } ], "gene_names_uniprotkb": "MstProx; CG1149; DmMstProx; Dmel\\CG1149; Dmel_CG1149; Mstprox; Tl-3; Toll-3; Toll3; dTLR3; dToll3; mstprox; toll", "gene_names_refseq": "CG1149; DmMstProx; Dmel\\CG1149; MstProx; Mstprox; Tl-3; Toll-3; Toll3; dTLR3; dToll3; mstprox; toll", "protein_names_uniprotkb": "MstProx", "protein_names_refseq": "CG1149-PA; MstProx-PA; MstProx; Toll-3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1149); (R-DME-168142); (R-DME-5686938); (R-DME-6798695)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24164", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VIA4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIB6-1", "uniprot_id": [ { "id": "Q9VIB6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIB6", "type": "external" } ], "mass": 63727.0, "length": 568, "protein_name": "carboxylesterase", "gene_name": "alpha-Est6", "organism": "Fruit fly", "refseq_name": "alpha-Esterase-6", "refseq_ac": [ { "id": "NP_524262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524262", "type": "external" } ], "gene_names_uniprotkb": "alpha-Est6; CG1108; DmalphaE6; Dmel\\CG1108; Dmel_CG1108; Esterase-6; E; F; G; aE6; alphaE6", "gene_names_refseq": "CG1108; DmalphaE6; Dmel\\CG1108; Esterase-6; E; F; G; aE6; alpha-Est6; alphaE6", "protein_names_uniprotkb": "carboxylesterase; 3.1.1.1", "protein_names_refseq": "CG1108-PA; Esterase-6; alpha-Est6-PA; alpha-Esterase-6; fragment E; fragment F; fragment G", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1108)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0106435 carboxylesterase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VIB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIH3-1", "uniprot_id": [ { "id": "MTP_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIH3", "type": "external" } ], "mass": 98776.0, "length": 886, "protein_name": "Microsomal triacylglycerol transfer protein", "gene_name": "Mtp", "organism": "Fruit fly", "refseq_name": "microsomal triacylglycerol transfer protein", "refseq_ac": [ { "id": "NP_610075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610075", "type": "external" } ], "gene_names_uniprotkb": "Mtp; CG9342", "gene_names_refseq": "2L3637; 2L4501; CG9342; CT3751; Dmel\\CG9342; MTP; Mtp; dMTP; mtp", "protein_names_uniprotkb": "Microsomal triacylglycerol transfer protein; MTP", "protein_names_refseq": "CG9342-PA; Mtp-PA; microsomal triacylglycerol transfer protein; microsomal triglyceride transfer protein", "tax_id": 7227, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); hypertension (Disease Ontology:DOID:10763); familial hyperlipidemia (Disease Ontology:DOID:1168); familial hypercholesterolemia (Disease Ontology:DOID:13810); abetalipoproteinemia (Disease Ontology:DOID:1386); hyperinsulinism (Disease Ontology:DOID:2018); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG9342); (R-DME-8964041)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;16478722", "class_list": "", "function": "Catalyzes the transport of phospholipids such as phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine) and phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine) between membranes. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q961S9", "ec_number_list": [], "go_molecular_function": "GO:0005548 phospholipid transporter activity;GO:0008289 lipid binding;GO:0008525 phosphatidylcholine transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0042157 lipoprotein metabolic process;GO:0048813 dendrite morphogenesis;GO:0008039 synaptic target recognition;GO:0035149 lumen formation, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VIH3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VII8-1", "uniprot_id": [ { "id": "Q9VII8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VII8", "type": "external" } ], "mass": 86249.0, "length": 775, "protein_name": "Outer segment 5", "gene_name": "Oseg5", "organism": "Fruit fly", "refseq_name": "outer segment 5", "refseq_ac": [ { "id": "NP_610064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610064", "type": "external" } ], "gene_names_uniprotkb": "Oseg5; CG9333; CHE-2; Che-2; Dmel\\CG9333; Dmel_CG9333; IFT80; OSEG5; OSEG; oseg5", "gene_names_refseq": "CG9333; CHE-2; Che-2; Dmel\\CG9333; IFT80; OSEG5; OSEG; Oseg5; oseg5", "protein_names_uniprotkb": "Outer segment 5", "protein_names_refseq": "CG9333-PB; Oseg5-PB; outer segment 5", "tax_id": 7227, "disease": "asphyxiating thoracic dystrophy (Disease Ontology:DOID:0050592); ciliopathy (Disease Ontology:DOID:0060340); asphyxiating thoracic dystrophy 2 (Disease Ontology:DOID:0110086); asphyxiating thoracic dystrophy 3 (Disease Ontology:DOID:0110087)", "pathway": " (dme:Dmel_CG9333)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005929 cilium;GO:0097730 non-motile cilium;GO:0030992 intraciliary transport particle B", "go_biological_process": "GO:0060271 cilium assembly;GO:1905515 non-motile cilium assembly;GO:0035721 intraciliary retrograde transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VII8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIP6-1", "uniprot_id": [ { "id": "Q9VIP6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIP6", "type": "external" } ], "mass": 75516.0, "length": 644, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG10730", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_610021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610021", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10730; 38B.7; CG10730; Dmel_CG10730; gi21430366; gi7298655", "gene_names_refseq": "38B.7; CG10730; Dmel\\CG10730; gi21430366; gi7298655", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG10730-PC; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10730)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VIP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIS4-1", "uniprot_id": [ { "id": "Q9VIS4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIS4", "type": "external" } ], "mass": 68025.0, "length": 604, "protein_name": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]", "gene_name": "Dus3", "organism": "Fruit fly", "refseq_name": "dihydrouridine synthase 3", "refseq_ac": [ { "id": "NP_610000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610000", "type": "external" } ], "gene_names_uniprotkb": "Dus3; CG10463; Dmel\\CG10463; Dmel_CG10463", "gene_names_refseq": "CG10463; Dmel\\CG10463; Dus3", "protein_names_uniprotkb": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; 1.3.1.-; tRNA-dihydrouridine synthase 3", "protein_names_refseq": "CG10463-PA; Dus3-PA; dihydrouridine synthase 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10463)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs. Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0017150 tRNA dihydrouridine synthase activity;GO:0106414 mRNA dihydrouridine synthase activity;GO:0102265 tRNA-dihydrouridine47 synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VIS4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIV8-1", "uniprot_id": [ { "id": "Q9VIV8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIV8", "type": "external" } ], "mass": 51299.0, "length": 454, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13084", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_609971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609971", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13084; CG13084; Dmel_CG13084", "gene_names_refseq": "CG13084; Dmel\\CG13084", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13084-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13084)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0042600 egg chorion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VIV8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VJ03-1", "uniprot_id": [ { "id": "Q9VJ03_DROME", "url": "https://www.uniprot.org/uniprot/Q9VJ03", "type": "external" } ], "mass": 59872.0, "length": 539, "protein_name": "Rieske domain-containing protein", "gene_name": "Dmel\\CG10700", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_609942", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609942", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10700; CG10700; Dmel_CG10700", "gene_names_refseq": "CG10700; Dmel\\CG10700", "protein_names_uniprotkb": "Rieske domain-containing protein", "protein_names_refseq": "CG10700-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10700)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0016651 oxidoreductase activity, acting on NAD(P)H", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0097194 execution phase of apoptosis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VJ03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VJ94-1", "uniprot_id": [ { "id": "Q9VJ94_DROME", "url": "https://www.uniprot.org/uniprot/Q9VJ94", "type": "external" } ], "mass": 116008.0, "length": 1068, "protein_name": "Dipeptidase", "gene_name": "CG31786; CG7198", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_724101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724101", "type": "external" } ], "gene_names_uniprotkb": "CG31786; CG7198; CG15157; CG15158; CG31746; CG31786; CG42400; CG42750; CG7167; CG7198; Dmel\\CG42750; Dmel_CG42750", "gene_names_refseq": "CG15157; CG15158; CG31746; CG31786; CG42400; CG42750; CG7167; CG7198; Dmel\\CG42750", "protein_names_uniprotkb": "Dipeptidase; 3.4.13.19", "protein_names_refseq": "CG42750-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42750); (R-DME-2142691); (R-DME-5423646)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.13.19", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.19", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0070573 metallodipeptidase activity;GO:0016805 dipeptidase activity", "go_cellular_component": "GO:0098552 side of membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VJ94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VJF7-1", "uniprot_id": [ { "id": "Q9VJF7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VJF7", "type": "external" } ], "mass": 44466.0, "length": 404, "protein_name": "Beaten path IIIb, isoform D", "gene_name": "beat-IIIb", "organism": "Fruit fly", "refseq_name": "beaten path IIIb, isoform D", "refseq_ac": [ { "id": "NP_788071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788071", "type": "external" } ], "gene_names_uniprotkb": "beat-IIIb; Beat-IIIb; CG15135; CG33179; CG4855; Dmel\\CG33179; Dmel_CG33179; beat IIIb", "gene_names_refseq": "Beat-IIIb; CG15135; CG33179; CG4855; Dmel\\CG33179; beat IIIb; beat-IIIb", "protein_names_uniprotkb": "Beaten path IIIb, isoform D", "protein_names_refseq": "CG33179-PD; beat-IIIb-PD; beaten path IIIb, isoform D", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0008045 motor neuron axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VJF7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VJY7-1", "uniprot_id": [ { "id": "Q9VJY7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VJY7", "type": "external" } ], "mass": 220026.0, "length": 1906, "protein_name": "Uncharacterized protein", "gene_name": "FBgn 32517", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_609648", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609648", "type": "external" } ], "gene_names_uniprotkb": "FBgn 32517; CG7099; Dmel\\CG7099; Dmel_CG7099; dTFIIIC220; dTFIIIC", "gene_names_refseq": "CG7099; Dmel\\CG7099; FBgn 32517; dTFIIIC220; dTFIIIC", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG7099-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7099); (R-DME-76061); (R-DME-76066)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0000127 transcription factor TFIIIC complex;GO:0005634 nucleus", "go_biological_process": "GO:0042791 5S class rRNA transcription by RNA polymerase III;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VJY7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VK10-1", "uniprot_id": [ { "id": "Q9VK10_DROME", "url": "https://www.uniprot.org/uniprot/Q9VK10", "type": "external" } ], "mass": 68677.0, "length": 639, "protein_name": "Phenoloxidase-activating factor 2", "gene_name": "l(2)k05911", "organism": "Fruit fly", "refseq_name": "lethal (2) k05911", "refseq_ac": [ { "id": "NP_723797", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_723797", "type": "external" } ], "gene_names_uniprotkb": "l(2)k05911; 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CG6508; Dmel_CG6508", "gene_names_refseq": "CG6508; Dmel\\CG6508", "protein_names_uniprotkb": "Peptidase A1 domain-containing protein", "protein_names_refseq": "CG6508-PA; uncharacterized protein", "tax_id": 7227, "disease": "atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": " (dme:Dmel_CG6508); (R-DME-2022377); (R-DME-2132295); (R-DME-5683826)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "GO:0006508 proteolysis;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VKP7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VKR4-1", "uniprot_id": [ { "id": "Q9VKR4_DROME", "url": "https://www.uniprot.org/uniprot/Q9VKR4", "type": "external" } ], "mass": 43421.0, "length": 405, "protein_name": "Aminomethyltransferase", "gene_name": "Gcst", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_609441", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609441", "type": "external" } ], "gene_names_uniprotkb": "Gcst; 151967_at; CG6415; Dmel\\CG6415; Dmel_CG6415; anon-32Aa", "gene_names_refseq": "151967_at; CG6415; Dmel\\CG6415; anon-32Aa", "protein_names_uniprotkb": "Aminomethyltransferase; 2.1.2.10; Glycine cleavage system T protein", "protein_names_refseq": "CG6415-PA; uncharacterized protein", "tax_id": 7227, "disease": "glycine encephalopathy 2 (Disease Ontology:DOID:0061001); glycine encephalopathy (Disease Ontology:DOID:9268)", "pathway": " (dme:Dmel_CG6415); (R-DME-6783984)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "The glycine cleavage system catalyzes the degradation of glycine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.10", "type": "external" } ], "go_molecular_function": "GO:0008483 transaminase activity;GO:0004047 aminomethyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005960 glycine cleavage complex", "go_biological_process": "GO:0019464 glycine decarboxylation via glycine cleavage system", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VKR4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VKR5-1", "uniprot_id": [ { "id": "Q9VKR5_DROME", "url": "https://www.uniprot.org/uniprot/Q9VKR5", "type": "external" } ], "mass": 47204.0, "length": 413, "protein_name": "Lipase", "gene_name": "Lip2", "organism": "Fruit fly", "refseq_name": "lipase 2, isoform A", "refseq_ac": [ { "id": "NP_524667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524667", "type": "external" } ], "gene_names_uniprotkb": "Lip2; CG17116; DILP2; Dmel\\CG17116; Dmel_CG17116; Dmlip2; dilp2; lip2", "gene_names_refseq": "CG17116; DILP2; Dmel\\CG17116; Dmlip2; Lip2; dilp2; lip2", "protein_names_uniprotkb": "Lipase", "protein_names_refseq": "CG17116-PA; Lip2-PA; lipase 2, isoform A; lipase 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17116); (R-DME-192456); (R-DME-6809371)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016298 lipase activity;GO:0004806 triacylglycerol lipase activity;GO:0016788 hydrolase activity, acting on ester bonds", "go_cellular_component": "", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VKR5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VKV9-1", "uniprot_id": [ { "id": "Q9VKV9_DROME", "url": "https://www.uniprot.org/uniprot/Q9VKV9", "type": "external" } ], "mass": 34869.0, "length": 317, "protein_name": "Methionine aminopeptidase", "gene_name": "MAP1B", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_609401", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609401", "type": "external" } ], "gene_names_uniprotkb": "MAP1B; CG5188; Dmel\\CG5188; Dmel_CG5188", "gene_names_refseq": "CG5188; Dmel\\CG5188; MAP1B", "protein_names_uniprotkb": "Methionine aminopeptidase; 3.4.11.18", "protein_names_refseq": "CG5188-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5188)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0070006 metalloaminopeptidase activity;GO:0004239 initiator methionyl aminopeptidase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VKV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VL65-1", "uniprot_id": [ { "id": "Q9VL65_DROME", "url": "https://www.uniprot.org/uniprot/Q9VL65", "type": "external" } ], "mass": 66615.0, "length": 566, "protein_name": "Dynein axonemal assembly factor 1 homolog", "gene_name": "TbCMF46", "organism": "Fruit fly", "refseq_name": "TbCMF46", "refseq_ac": [ { "id": "NP_609325", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609325", "type": "external" } ], "gene_names_uniprotkb": "TbCMF46; CG13125; CT32363; Dmel\\CG13125; Dmel_CG13125; mel CG13125", "gene_names_refseq": "CG13125; CT32363; Dmel\\CG13125; TbCMF46; mel CG13125", "protein_names_uniprotkb": "Dynein axonemal assembly factor 1 homolog; Defective transmitter-recycling protein; Dynein regulatory complex subunit 3; Leucine-rich repeat-containing protein 50 homolog", "protein_names_refseq": "CG13125-PA; TbCMF46-PA; TbCMF46", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13125)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Cilium-specific protein required for cilia structures., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VL65-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VL88-1", "uniprot_id": [ { "id": "Q9VL88_DROME", "url": "https://www.uniprot.org/uniprot/Q9VL88", "type": "external" } ], "mass": 63716.0, "length": 553, "protein_name": "Pickpocket 18", "gene_name": "ppk18", "organism": "Fruit fly", "refseq_name": "pickpocket 18", "refseq_ac": [ { "id": "NP_609308", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609308", "type": "external" } ], "gene_names_uniprotkb": "ppk18; 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CG31560; Dmel\\CG31560; Dmel_CG31560", "gene_names_refseq": "CG10314; CG31560; Dmel\\CG31560", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG31560-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31560)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VNN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VP02-1", "uniprot_id": [ { "id": "Q9VP02_DROME", "url": "https://www.uniprot.org/uniprot/Q9VP02", "type": "external" } ], "mass": 41600.0, "length": 370, "protein_name": "Aldose 1-epimerase", "gene_name": "Galm1", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_730670", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730670", "type": "external" } ], "gene_names_uniprotkb": "Galm1; BcDNA:GH08902; CG12562; CG14576; CG32444; CT3430; Dmel\\CG32444; Dmel_CG32444; aldose 1-epi", "gene_names_refseq": "BcDNA:GH08902; CG12562; CG14576; CG32444; CT3430; Dmel\\CG32444; aldose 1-epi", "protein_names_uniprotkb": "Aldose 1-epimerase; 5.1.3.3", "protein_names_refseq": "CG32444-PA; aldose 1-epimerase; uncharacterized protein", "tax_id": 7227, "disease": "galactosemia 4 (Disease Ontology:DOID:0060969)", "pathway": " (dme:Dmel_CG32444)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. 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CG10879; CG33124; Dmel\\CG33124; Dmel_CG33124; dSLC5A13", "gene_names_refseq": "CG10879; CG33124-PB; CG33124; Dmel\\CG33124; dSLC5A13", "protein_names_uniprotkb": "Sodium-coupled monocarboxylate transporter 1", "protein_names_refseq": "CG33124-PD; uncharacterized protein", "tax_id": 7227, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); thyroid dyshormonogenesis 1 (Disease Ontology:DOID:0112185)", "pathway": " (dme:Dmel_CG33124)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006814 sodium ion transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQ85-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VQB8-1", "uniprot_id": [ { "id": "Q9VQB8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VQB8", "type": "external" } ], "mass": 51250.0, "length": 459, "protein_name": "Phosphatidylinositol-glycan biosynthesis class W protein", "gene_name": "PIG-Wa", "organism": "Fruit fly", "refseq_name": "phosphatidylinositol glycan anchor biosynthesis class W a", "refseq_ac": [ { "id": "NP_608679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608679", "type": "external" } ], "gene_names_uniprotkb": "PIG-Wa; CG9870; Dmel\\CG9870; Dmel_CG9870; PIG-W; PIGWWa", "gene_names_refseq": "CG9870; Dmel\\CG9870; PIG-Wa; PIG-W; PIGWWa", "protein_names_uniprotkb": "Phosphatidylinositol-glycan biosynthesis class W protein; 2.3.-.-", "protein_names_refseq": "CG9870-PA; PIG-Wa-PA; phosphatidylinositol glycan anchor biosynthesis class W a", "tax_id": 7227, "disease": "hyperphosphatasia with impaired intellectual development syndrome 5 (Disease Ontology:DOID:0070432)", "pathway": " (dme:Dmel_CG9870)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032216 glucosaminyl-phosphatidylinositol O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQB8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VQG6-1", "uniprot_id": [ { "id": "Q9VQG6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VQG6", "type": "external" } ], "mass": 28363.0, "length": 242, "protein_name": "Rab-like protein 3", "gene_name": "Dmel\\CG15399", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_608712", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608712", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG15399; CG15399; Dmel_CG15399", "gene_names_refseq": "CG15399; Dmel\\CG15399", "protein_names_uniprotkb": "Rab-like protein 3", "protein_names_refseq": "CG15399-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15399)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0012505 endomembrane system", "go_biological_process": "GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VQI0-1", "uniprot_id": [ { "id": "Q9VQI0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VQI0", "type": "external" } ], "mass": 39959.0, "length": 344, "protein_name": "N-acetylgalactosaminide beta-1,3-galactosyltransferase", "gene_name": "Dmel\\CG2983", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_608723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608723", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG2983; CG2983; Dmel_CG2983; dC1GalT8", "gene_names_refseq": "CG2983; Dmel\\CG2983; dC1GalT8", "protein_names_uniprotkb": "N-acetylgalactosaminide beta-1,3-galactosyltransferase; 2.4.1.122", "protein_names_refseq": "CG2983-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2983); (R-DME-913709)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "glycogene;glycosyltransferase", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.122", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.122", "type": "external" } ], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VQI7-1", "uniprot_id": [ { "id": "Q9VQI7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VQI7", "type": "external" } ], "mass": 24846.0, "length": 222, "protein_name": "1-Cys peroxiredoxin", "gene_name": "Prx6a", "organism": "Fruit fly", "refseq_name": "peroxiredoxin 6a", "refseq_ac": [ { "id": "NP_523463", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523463", "type": "external" } ], "gene_names_uniprotkb": "Prx6a; 153181_at; CG3083; DPx-6005; DPx6005; Dmel\\CG3083; Dmel_CG3083; GM04269p; Prx6005; dPRDX6-1; dPRDX6; dPrx6b", "gene_names_refseq": "153181_at; CG3083; DPx-6005; DPx6005; Dmel\\CG3083; GM04269p; Prx6005; Prx6a; dPRDX6-1; dPRDX6; dPrx6b", "protein_names_uniprotkb": "1-Cys peroxiredoxin", "protein_names_refseq": "CG3083-PA; Prx6a-PA; peroxiredoxin 6005; peroxiredoxin 6a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3083); (R-DME-6798695)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. 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CG17262; Cnir; Dmel\\CG17262; Dmel_CG17262", "gene_names_refseq": "CG17262; Cnir; Dmel\\CG17262; cnir", "protein_names_uniprotkb": "Cornichon related", "protein_names_refseq": "CG17262-PA; Cni-related; cnir-PA; cornichon related", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17262)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VQL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VR18-1", "uniprot_id": [ { "id": "Q9VR18_DROME", "url": "https://www.uniprot.org/uniprot/Q9VR18", "type": "external" } ], "mass": 103341.0, "length": 919, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG11929", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_608849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608849", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG11929; 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CG5592; Dmel_CG5592", "gene_names_refseq": "CG5592; Dmel\\CG5592", "protein_names_uniprotkb": "Major facilitator superfamily (MFS) profile domain-containing protein", "protein_names_refseq": "CG5592-PA; uncharacterized protein", "tax_id": 7227, "disease": "kidney failure (Disease Ontology:DOID:1074); extrahepatic cholestasis (Disease Ontology:DOID:13619); intrahepatic cholestasis (Disease Ontology:DOID:1852); hyperuricemia (Disease Ontology:DOID:1920); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG5592); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VRQ8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VRT1-1", "uniprot_id": [ { "id": "Q9VRT1_DROME", "url": "https://www.uniprot.org/uniprot/Q9VRT1", "type": "external" } ], "mass": 49221.0, "length": 438, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG6592", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_648016", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648016", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG6592; 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CG5661; DSema 3a; DSema 5C; Sema-3a; Sema-5c; sema 5c", "gene_names_refseq": "BEST:CK02567; BG01245; CG5661; CK02567; CT17880; Dmel\\CG5661; Dsema3a; Sema 5c; Sema-3a; Sema-5C; Sema-5c; Sema-5; Sema3A; Sema5c; sema 5c; sema-5C; sema-5c; sema5c", "protein_names_uniprotkb": "Semaphorin 5c", "protein_names_refseq": "CG5661-PA; Sema-3a; Sema-5c; Sema5c-PA; Semaphorin-5c; semaphorin 5C; semaphorin 5c, isoform A; semaphorin; semiphorin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5661); (R-DME-416700); (R-DME-5173214)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "10704872;10731132;11458392;12537572;17435226;30827914;37041188", "class_list": "", "function": "Regulates the motility of migrating epithelial cells by providing guidance cues within the migratory environment and may also play a role in development of the olfactory system (PubMed:17435226, PubMed:30827914). May act as a positive axonal guidance cue (By similarity). Function in neurons is essential for adult survival and is important for climbing behavior (PubMed:37041188). Promotes collective migration of follicular epithelial cells in egg chambers, likely by acting at the leading edge of the basal epithelium cells to provide guidance cues across the cell boundary to the trailing edge of the cell ahead (PubMed:30827914). The transmembrane receptor PlexA on the trailing edge of the cell ahead, appears to transduce this signal to suppress the formation of protrusions (PubMed:30827914). Involved in olfactory avoidance behavior (PubMed:17435226)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 11, "predicted_n_glycosites": 10, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "Q7YU67;Q9U631", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0042048 olfactory behavior;GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VTT0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VU21-1", "uniprot_id": [ { "id": "Q9VU21_DROME", "url": "https://www.uniprot.org/uniprot/Q9VU21", "type": "external" } ], "mass": 35405.0, "length": 308, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG10943", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_648609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648609", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10943; 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CG14107; Dmel_CG14107", "gene_names_refseq": "CG14107; Dmel\\CG14107", "protein_names_uniprotkb": "Nucleolin", "protein_names_refseq": "CG14107-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14107)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VU61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VU94-1", "uniprot_id": [ { "id": "Q9VU94_DROME", "url": "https://www.uniprot.org/uniprot/Q9VU94", "type": "external" } ], "mass": 426245.0, "length": 3843, "protein_name": "Hemolectin, isoform A", "gene_name": "Hml", "organism": "Fruit fly", "refseq_name": "hemolectin, isoform A", "refseq_ac": [ { "id": "NP_524060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524060", "type": "external" } ], "gene_names_uniprotkb": "Hml; CG7002; CT21553; Dmel\\CG7002; Dmel_CG7002; d-hml; hml", "gene_names_refseq": "CG7002; CT21553; Dmel\\CG7002; Hml; d-hml; hml", "protein_names_uniprotkb": "Hemolectin, isoform A", "protein_names_refseq": "CG7002-PA; Hml-PA; hemolectin, isoform A; hemolectin", "tax_id": 7227, "disease": "sinusitis (Disease Ontology:DOID:0050127); inflammatory bowel disease (Disease Ontology:DOID:0050589); biliary tract benign neoplasm (Disease Ontology:DOID:0050625); pre-malignant neoplasm (Disease Ontology:DOID:0060071); colitis (Disease Ontology:DOID:0060180); scoliosis (Disease Ontology:DOID:0060249); idiopathic scoliosis (Disease Ontology:DOID:0060250); interstitial lung disease 2 (Disease Ontology:DOID:0060971); mucositis (Disease Ontology:DOID:0080178); autosomal recessive nonsyndromic deafness 18B (Disease Ontology:DOID:0110474); dry eye syndrome (Disease Ontology:DOID:10140); otitis media (Disease Ontology:DOID:10754); gastric ulcer (Disease Ontology:DOID:10808); urinary bladder cancer (Disease Ontology:DOID:11054); allergic conjunctivitis (Disease Ontology:DOID:11204); primary biliary cholangitis (Disease Ontology:DOID:12236); Sjogren's syndrome (Disease Ontology:DOID:12894); angle-closure glaucoma (Disease Ontology:DOID:13550); cystic fibrosis (Disease Ontology:DOID:1485); cystitis (Disease Ontology:DOID:1679); glaucoma (Disease Ontology:DOID:1686); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); asthma (Disease Ontology:DOID:2841); bronchiolitis (Disease Ontology:DOID:2942); mucinous adenocarcinoma (Disease Ontology:DOID:3030); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); ischemia (Disease Ontology:DOID:326); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); pulmonary fibrosis (Disease Ontology:DOID:3770); allergic rhinitis (Disease Ontology:DOID:4481); rhinitis (Disease Ontology:DOID:4483); common bile duct neoplasm (Disease Ontology:DOID:4608); cholangiocarcinoma (Disease Ontology:DOID:4947); liver cirrhosis (Disease Ontology:DOID:5082); intestinal disease (Disease Ontology:DOID:5295); pneumonia (Disease Ontology:DOID:552); stomach disease (Disease Ontology:DOID:76); corneal ulcer (Disease Ontology:DOID:8463); ulcerative colitis (Disease Ontology:DOID:8577); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); Barrett's esophagus (Disease Ontology:DOID:9206); nasopharynx carcinoma (Disease Ontology:DOID:9261); keratoconjunctivitis (Disease Ontology:DOID:9368)", "pathway": " (dme:Dmel_CG7002); (R-DME-5173214); (R-DME-913709); (R-DME-977068)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 44, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0042803 protein homodimerization activity;GO:0005201 extracellular matrix structural constituent;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007399 nervous system development;GO:0007599 hemostasis;GO:0042060 wound healing;GO:0042381 hemolymph coagulation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VU94-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VUB7-1", "uniprot_id": [ { "id": "Q9VUB7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VUB7", "type": "external" } ], "mass": 262468.0, "length": 2294, "protein_name": "PAX-interacting protein 1", "gene_name": "Ptip", "organism": "Fruit fly", "refseq_name": "PAX transcription activation domain interacting protein", "refseq_ac": [ { "id": "NP_729947", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729947", "type": "external" } ], "gene_names_uniprotkb": "Ptip; CG32133; CG6532; CG8797; Dmel\\CG32133; Dmel_CG32133; PTIP; ptip", "gene_names_refseq": "CG32133; CG6532; CG8797; Dmel\\CG32133; PTIP; Ptip; ptip", "protein_names_uniprotkb": "PAX-interacting protein 1; PAX transactivation activation domain-interacting protein", "protein_names_refseq": "CG32133-PA; PAX transcription activation domain interacting protein; PAX transcription activation domain-interacting protein; Ptip-PA", "tax_id": 7227, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (dme:Dmel_CG32133); (R-DME-3108214); (R-DME-5693565)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0044666 MLL3/4 complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0007507 heart development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006974 DNA damage response;GO:0009880 embryonic pattern specification", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VUB7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VUM6-1", "uniprot_id": [ { "id": "Q9VUM6_DROME", "url": "https://www.uniprot.org/uniprot/Q9VUM6", "type": "external" } ], "mass": 61485.0, "length": 526, "protein_name": "Bestrophin homolog", "gene_name": "Best4", "organism": "Fruit fly", "refseq_name": "bestrophin 4", "refseq_ac": [ { "id": "NP_001097609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097609", "type": "external" } ], "gene_names_uniprotkb": "Best4; CG7259; CT22395; Dmel\\CG7259; Dmel_CG7259; dBest4; dbest4", "gene_names_refseq": "Best4; CG7259; CT22395; Dmel\\CG7259; dBest4; dbest4", "protein_names_uniprotkb": "Bestrophin homolog", "protein_names_refseq": "Best4-PB; CG7259-PB; bestrophin 4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7259); (R-DME-2672351)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Forms chloride channels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005254 chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0006821 chloride transport;GO:1902476 chloride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VUM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VUR1-1", "uniprot_id": [ { "id": "Q9VUR1_DROME", "url": "https://www.uniprot.org/uniprot/Q9VUR1", "type": "external" } ], "mass": 56652.0, "length": 499, "protein_name": "General transcription factor IIH subunit 4", "gene_name": "mrn", "organism": "Fruit fly", "refseq_name": "marionette", "refseq_ac": [ { "id": "NP_648780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648780", "type": "external" } ], "gene_names_uniprotkb": "mrn; 154538_at; CG7764; Dmel\\CG7764; Dmel_CG7764; Dmp52; TFB2; Tfb2; anon-WO0118547.648; l(3)E35; ms(3)nc16; nc16; p52", "gene_names_refseq": "154538_at; CG7764; Dmel\\CG7764; Dmp52; TFB2; Tfb2; anon-WO0118547.648; l(3)E35; mrn; ms(3)nc16; nc16; p52", "protein_names_uniprotkb": "General transcription factor IIH subunit 4", "protein_names_refseq": "CG7764-PA; Tfb2; marionette; marionnette; mrn-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7764); (R-DME-112382); (R-DME-113418); (R-DME-5696395); (R-DME-5696400); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-72086); (R-DME-73772); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075)", "pathway_count": 18, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005675 transcription factor TFIIH holo complex;GO:0000439 transcription factor TFIIH core complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006289 nucleotide-excision repair;GO:0001111 RNA polymerase II promoter clearance;GO:0001113 transcription open complex formation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VUR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VUT0-1", "uniprot_id": [ { "id": "Q9VUT0_DROME", "url": "https://www.uniprot.org/uniprot/Q9VUT0", "type": "external" } ], "mass": 11167.0, "length": 98, "protein_name": "Ecdysone-induced gene 71Eg", "gene_name": "Eig71Eg", "organism": "Fruit fly", "refseq_name": "Ecdysone-induced gene 71Eg", "refseq_ac": [ { "id": "NP_524094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524094", "type": "external" } ], "gene_names_uniprotkb": "Eig71Eg; CG7336; Dmel\\CG7336; Dmel_CG7336; L71-6; L71; VI; eig71Eg; gene VI; gene-VI", "gene_names_refseq": "CG7336; Dmel\\CG7336; Eig71Eg; L71-6; L71; VI; eig71Eg; gene VI; gene-VI", "protein_names_uniprotkb": "Ecdysone-induced gene 71Eg", "protein_names_refseq": "71E-Gene-VI; CG7336-PA; Ecdysone-induced gene 71Eg; Eig71Eg-PA; gene VI", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7336)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VUT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VUY2-1", "uniprot_id": [ { "id": "Q9VUY2_DROME", "url": "https://www.uniprot.org/uniprot/Q9VUY2", "type": "external" } ], "mass": 50478.0, "length": 451, "protein_name": "Ig-like domain-containing protein", "gene_name": "Dmel\\CG13074", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_648835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648835", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13074; CG13074; Dmel_CG13074", "gene_names_refseq": "CG13074; Dmel\\CG13074", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "CG13074-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13074)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005868 cytoplasmic dynein complex;GO:0097014 ciliary plasm", "go_biological_process": "GO:0042073 intraciliary transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VUY2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VV06-1", "uniprot_id": [ { "id": "Q9VV06_DROME", "url": "https://www.uniprot.org/uniprot/Q9VV06", "type": "external" } ], "mass": 17517.0, "length": 152, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13070", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_648854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648854", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13070; CG13070; Dmel_CG13070; FBgn0036586", "gene_names_refseq": "CG13070; Dmel\\CG13070; FBgn0036586", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13070-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13070)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VV06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VV20-1", "uniprot_id": [ { "id": "Q9VV20_DROME", "url": "https://www.uniprot.org/uniprot/Q9VV20", "type": "external" } ], "mass": 19098.0, "length": 187, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13045", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_648864", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648864", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13045; CG13045; Dmel_CG13045", "gene_names_refseq": "CG13045; Dmel\\CG13045", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13045-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13045)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VV20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VV59-1", "uniprot_id": [ { "id": "Q9VV59_DROME", "url": "https://www.uniprot.org/uniprot/Q9VV59", "type": "external" } ], "mass": 58509.0, "length": 511, "protein_name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "gene_name": "GluRS-m", "organism": "Fruit fly", "refseq_name": "Glutamyl-tRNA synthetase, mitochondrial", "refseq_ac": [ { "id": "NP_648894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648894", "type": "external" } ], "gene_names_uniprotkb": "GluRS-m; CG4573; Dmel\\CG4573; Dmel_CG4573", "gene_names_refseq": "CG4573; Dmel\\CG4573; GluRS-m", "protein_names_uniprotkb": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial; 6.1.1.17; 6.1.1.24; Glutamate--tRNA(Gln) ligase EARS2, mitochondrial; Glutamyl-tRNA synthetase; Mitochondrial glutamyl-tRNA synthetase", "protein_names_refseq": "CG4573-PA; GluRS-m-PA; Glutamyl-tRNA synthetase, mitochondrial", "tax_id": 7227, "disease": "combined oxidative phosphorylation deficiency 12 (Disease Ontology:DOID:0111493)", "pathway": " (dme:Dmel_CG4573)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.15", "type": "external" }, { "id": "6.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.17", "type": "external" }, { "id": "6.1.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.24", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0000049 tRNA binding;GO:0004818 glutamate-tRNA ligase activity;GO:0050561 glutamate-tRNA(Gln) ligase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006424 glutamyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VV59-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VVK2-1", "uniprot_id": [ { "id": "Q9VVK2_DROME", "url": "https://www.uniprot.org/uniprot/Q9VVK2", "type": "external" } ], "mass": 54408.0, "length": 479, "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG6034", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_649005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649005", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG6034; CG6034; Dmel_CG6034", "gene_names_refseq": "CG6034; Dmel\\CG6034", "protein_names_uniprotkb": "Amine oxidase domain-containing protein", "protein_names_refseq": "CG6034-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6034); (R-DME-141334); (R-DME-351200)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046592 polyamine oxidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VVK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VVU7-1", "uniprot_id": [ { "id": "Q9VVU7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VVU7", "type": "external" } ], "mass": 78110.0, "length": 675, "protein_name": "Ionotropic receptor 75d", "gene_name": "Ir75d", "organism": "Fruit fly", "refseq_name": "ionotropic receptor 75d", "refseq_ac": [ { "id": "NP_649074", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649074", "type": "external" } ], "gene_names_uniprotkb": "Ir75d; 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CG3808; Dmel\\CG3808; Dmel_CG3808; cg3808", "gene_names_refseq": "CG3808; Dmel\\CG3808; cg3808", "protein_names_uniprotkb": "tRNA (uracil(54)-C(5))-methyltransferase; 2.1.1.35", "protein_names_refseq": "CG3808-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3808)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.35", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0030697 tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent", "go_cellular_component": "", "go_biological_process": "GO:0006396 RNA processing;GO:0009451 RNA modification;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VVV7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VVV8-1", "uniprot_id": [ { "id": "Q9VVV8_DROME", "url": "https://www.uniprot.org/uniprot/Q9VVV8", "type": "external" } ], "mass": 60347.0, "length": 530, "protein_name": "SET and MYND domain containing, arthropod-specific, member 2", "gene_name": "SmydA-2", "organism": "Fruit fly", "refseq_name": "SET and MYND domain containing, arthropod-specific, member 2", "refseq_ac": [ { "id": "NP_649084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649084", "type": "external" } ], "gene_names_uniprotkb": "SmydA-2; 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The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. 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CG13561; Dmel_CG13561", "gene_names_refseq": "CG13561; Dmel\\CG13561", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13561-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13561)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W1J6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W1J7-1", "uniprot_id": [ { "id": "Q9W1J7_DROME", "url": "https://www.uniprot.org/uniprot/Q9W1J7", "type": "external" } ], "mass": 18544.0, "length": 157, "protein_name": "SKP1 component POZ domain-containing protein", "gene_name": "Dmel\\CG15800", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_611828", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611828", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG15800; CG15800; Dmel_CG15800; SkpG", "gene_names_refseq": "CG15800; Dmel\\CG15800; SkpG", "protein_names_uniprotkb": "SKP1 component POZ domain-containing protein", "protein_names_refseq": "CG15800-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15800)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0097602 cullin family protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W1J7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W1U0-1", "uniprot_id": [ { "id": "Q9W1U0_DROME", "url": "https://www.uniprot.org/uniprot/Q9W1U0", "type": "external" } ], "mass": 9898.0, "length": 98, "protein_name": "Cuticle protein 16.5", "gene_name": "Dmel\\CG13545", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_611763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611763", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13545; CG13545; Dmel_CG13545", "gene_names_refseq": "CG13545; Dmel\\CG13545", "protein_names_uniprotkb": "Cuticle protein 16.5", "protein_names_refseq": "CG13545-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13545)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W1U0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W2C9-1", "uniprot_id": [ { "id": "Q9W2C9_DROME", "url": "https://www.uniprot.org/uniprot/Q9W2C9", "type": "external" } ], "mass": 57908.0, "length": 511, "protein_name": "1.4.3.-; 1.4.3.13; Lysyl oxidase-like 2", "gene_name": "Loxl2", "organism": "Fruit fly", "refseq_name": "lysyl oxidase-like 2", "refseq_ac": [ { "id": "NP_523806", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523806", "type": "external" } ], "gene_names_uniprotkb": "Loxl2; CG4402; Dmel\\CG4402; Dmel_CG4402; Dmloxl-2; LOX; dmlox-2; lox2", "gene_names_refseq": "CG4402; Dmel\\CG4402; Dmloxl-2; LOX; Loxl2; dmlox-2; lox2", "protein_names_uniprotkb": "1.4.3.-; 1.4.3.13; Lysyl oxidase-like 2", "protein_names_refseq": "CG4402-PA; Loxl2-PA; lysyl oxidase-like 2", "tax_id": 7227, "disease": "primary open angle glaucoma (Disease Ontology:DOID:1070); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); myopia (Disease Ontology:DOID:11830); exfoliation syndrome (Disease Ontology:DOID:13641)", "pathway": " (dme:Dmel_CG4402); (R-DME-2243919)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" }, { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W2C9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W2E9-1", "uniprot_id": [ { "id": "Q9W2E9_DROME", "url": "https://www.uniprot.org/uniprot/Q9W2E9", "type": "external" } ], "mass": 97717.0, "length": 902, "protein_name": "Kinase", "gene_name": "Ip6k", "organism": "Fruit fly", "refseq_name": "inositol hexakisphosphate kinase, isoform A", "refseq_ac": [ { "id": "NP_726095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726095", "type": "external" } ], "gene_names_uniprotkb": "Ip6k; CG10082; Dmel\\CG10082; Dmel_CG10082; anon-WO0172774.149; dmIP6K", "gene_names_refseq": "CG10082; Dmel\\CG10082; Ip6k; anon-WO0172774.149; dmIP6K", "protein_names_uniprotkb": "Kinase; 2.7.-.-", "protein_names_refseq": "3-hydroxyisobutyryl-CoA hydrolase; CG10082-PA; Ip6k-PA; inositol hexakisphosphate kinase, isoform A", "tax_id": 7227, "disease": "", "pathway": " (R-DME-1855167); (R-DME-1855191)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.-.-", "type": "external" } ], "go_molecular_function": "GO:0000828 inositol hexakisphosphate kinase activity;GO:0000832 inositol hexakisphosphate 5-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0032958 inositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W2E9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W2M5-1", "uniprot_id": [ { "id": "Q9W2M5_DROME", "url": "https://www.uniprot.org/uniprot/Q9W2M5", "type": "external" } ], "mass": 40778.0, "length": 368, "protein_name": "3.2.1.-; 3.2.1.14; Chitinase 9", "gene_name": "Cht9", "organism": "Fruit fly", "refseq_name": "chitinase 9", "refseq_ac": [ { "id": "NP_611543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611543", "type": "external" } ], "gene_names_uniprotkb": "Cht9; CG10531; Cht; DmCHT9; DmCht9; Dmel\\CG10531; Dmel_CG10531; cht9", "gene_names_refseq": "CG10531; Cht9; Cht; DmCHT9; DmCht9; Dmel\\CG10531; cht9", "protein_names_uniprotkb": "3.2.1.-; 3.2.1.14; Chitinase 9", "protein_names_refseq": "CG10531-PA; Cht9-PA; chitinase 9", "tax_id": 7227, "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); sinusitis (Disease Ontology:DOID:0050127); idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); small cell carcinoma (Disease Ontology:DOID:0050685); colorectal carcinoma (Disease Ontology:DOID:0080199); prostate carcinoma (Disease Ontology:DOID:10286); silicosis (Disease Ontology:DOID:10325); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); cryptococcosis (Disease Ontology:DOID:12053); temporal arteritis (Disease Ontology:DOID:13375); pulmonary sarcoidosis (Disease Ontology:DOID:13406); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); melanoma (Disease Ontology:DOID:1909); arteriosclerosis (Disease Ontology:DOID:2349); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); ovarian cancer (Disease Ontology:DOID:2394); asthma (Disease Ontology:DOID:2841); glioblastoma (Disease Ontology:DOID:3068); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); chondrosarcoma (Disease Ontology:DOID:3371); coronary artery disease (Disease Ontology:DOID:3393); pulmonary fibrosis (Disease Ontology:DOID:3770); lung non-small cell carcinoma (Disease Ontology:DOID:3908); systemic scleroderma (Disease Ontology:DOID:418); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); neuromyelitis optica (Disease Ontology:DOID:8869); acute myeloid leukemia (Disease Ontology:DOID:9119); type 2 diabetes mellitus (Disease Ontology:DOID:9352); bacterial meningitis (Disease Ontology:DOID:9470); multiple myeloma (Disease Ontology:DOID:9538); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG10531); (R-DME-189085); (R-DME-6798695)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZW4", "ec_number_list": [ { "id": "3.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.17", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "3.5.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.28", "type": "external" }, { "id": "3.2.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.14", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.3", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "3.4.17.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.13", "type": "external" }, { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0004568 chitinase activity;GO:0008843 endochitinase activity;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0042060 wound healing;GO:0006032 chitin catabolic process;GO:0018990 ecdysis, chitin-based cuticle;GO:0040003 chitin-based cuticle development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W2M5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W2Q2-1", "uniprot_id": [ { "id": "Q9W2Q2_DROME", "url": "https://www.uniprot.org/uniprot/Q9W2Q2", "type": "external" } ], "mass": 37623.0, "length": 332, "protein_name": "4.2.1.1; 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CG11556; Dmel\\CG11556; Dmel_CG11556; Rph3A; rph", "gene_names_refseq": "CG11556; Dmel\\CG11556; Rph3A; Rph; rph", "protein_names_uniprotkb": "Rabphilin, isoform A", "protein_names_refseq": "CG11556-PA; Rph-PA; dm-rabphilin; rabphilin, isoform A; rabphilin-3A", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515)", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031267 small GTPase binding;GO:0005544 calcium-dependent phospholipid binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0030141 secretory granule;GO:0045202 synapse;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0045956 positive regulation of calcium ion-dependent exocytosis;GO:0016079 synaptic vesicle exocytosis;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W2R9-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W2S7-1", "uniprot_id": [ { "id": "Q9W2S7_DROME", "url": "https://www.uniprot.org/uniprot/Q9W2S7", "type": "external" } ], "mass": 108046.0, "length": 931, "protein_name": "Aminopeptidase", "gene_name": "pepCG2111", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_572644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572644", "type": "external" } ], "gene_names_uniprotkb": "pepCG2111; 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7b; CG15326; DmelIR7b; Dmel\\CG15326; Dmel_CG15326; IR7b", "gene_names_refseq": "7b; CG15326; DmelIR7b; Dmel\\CG15326; IR7b; Ir7b", "protein_names_uniprotkb": "Ionotropic receptor 7b", "protein_names_refseq": "CG15326-PB; Ir7b-PB; ionotropic receptor 7b", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15326)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0009593 detection of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W3P4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W3P8-1", "uniprot_id": [ { "id": "Q9W3P8_DROME", "url": "https://www.uniprot.org/uniprot/Q9W3P8", "type": "external" } ], "mass": 70467.0, "length": 614, "protein_name": "Ionotropic receptor 7a", "gene_name": "Ir7a", "organism": "Fruit fly", "refseq_name": "ionotropic receptor 7a", "refseq_ac": [ { "id": "NP_572406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572406", "type": "external" } ], "gene_names_uniprotkb": "Ir7a; 7a; CG12663; DmelIR7a; Dmel\\CG12663; Dmel_CG12663; IR7a", "gene_names_refseq": "7a; CG12663; DmelIR7a; Dmel\\CG12663; IR7a; Ir7a", "protein_names_uniprotkb": "Ionotropic receptor 7a", "protein_names_refseq": "CG12663-PA; Ir7a-PA; ionotropic receptor 7a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12663)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0009593 detection of chemical stimulus;GO:0050909 sensory perception of taste;GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W3P8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W451-1", "uniprot_id": [ { "id": "Q9W451_DROME", "url": "https://www.uniprot.org/uniprot/Q9W451", "type": "external" } ], "mass": 207238.0, "length": 1836, "protein_name": "Female sterile (1) M3", "gene_name": "fs(1)M3", "organism": "Fruit fly", "refseq_name": "female sterile (1) M3", "refseq_ac": [ { "id": "NP_572284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572284", "type": "external" } ], "gene_names_uniprotkb": "fs(1)M3; CG4790; Dmel\\CG4790; Dmel_CG4790; Fs(1)K646; fs(1)K646; fs(1)phl; fs(1)ph; fs(1)pole hole; fs(1)polehole", "gene_names_refseq": "CG4790; Dmel\\CG4790; Fs(1)K646; fs(1)K646; fs(1)M3; fs(1)phl; fs(1)ph; fs(1)pole hole; fs(1)polehole", "protein_names_uniprotkb": "Female sterile (1) M3", "protein_names_refseq": "CG4790-PA; female sterile (1) M3; fs(1)M3-PA; fs(1)polehole; polehole", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4790)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007304 chorion-containing eggshell formation;GO:0007305 vitelline membrane formation involved in chorion-containing eggshell formation;GO:0007362 terminal region determination;GO:0008293 torso signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9W451-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W466-1", "uniprot_id": [ { "id": "Q9W466_DROME", "url": "https://www.uniprot.org/uniprot/Q9W466", "type": "external" } ], "mass": 26071.0, "length": 233, "protein_name": "PI31 proteasome regulator N-terminal domain-containing protein", "gene_name": "Dmel\\CG12729", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_572271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572271", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG12729; 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CG3208; Dmel\\CG3208; Dmel_CG3208; RhoGAP", "gene_names_refseq": "CG3208; Dmel\\CG3208; RhoGAP5A; RhoGAP", "protein_names_uniprotkb": "Rho GTPase activating protein at 5A, isoform A", "protein_names_refseq": "CG3208-PA; Rho GTPase activating protein at 5A, isoform A; RhoGAP5A-PA", "tax_id": 7227, "disease": "Duane retraction syndrome 2 (Disease Ontology:DOID:0061028); Duane retraction syndrome (Disease Ontology:DOID:12557)", "pathway": " (R-DME-9013148); (R-DME-9013149)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0048749 compound eye development;GO:0007165 signal transduction;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W4A9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9W4D8-1", "uniprot_id": [ { "id": "Q9W4D8_DROME", "url": "https://www.uniprot.org/uniprot/Q9W4D8", "type": "external" } ], "mass": 30446.0, "length": 272, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG17764", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_572211", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572211", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG17764; 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CG15720; CG18646; CG42628; CG42629; CG4346; CG4368; CG44424; Dmel\\CG44424; Dmel_CG44424; FBpp0073550; R5_X:12971309..12973132; Rad; Rsh; rad", "gene_names_refseq": "CG15720; CG18646; CG42628; CG42629; CG4346; CG4368; CG44424; Dmel\\CG44424; FBpp0073550; R5_X:12971309..12973132; Rad; Rsh; rad; rsh", "protein_names_uniprotkb": "Radish, isoform I", "protein_names_refseq": "CG44424-PI; radish, isoform I; radish; rsh-PI", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG44424)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030424 axon;GO:0043025 neuronal cell body", "go_biological_process": "GO:0051056 regulation of small GTPase mediated signal transduction;GO:0008016 regulation of heart contraction;GO:0008355 olfactory learning;GO:0007615 anesthesia-resistant memory", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JDH0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JD41-1", "uniprot_id": [ { "id": "X2JD41_DROME", "url": "https://www.uniprot.org/uniprot/X2JD41", "type": "external" } ], "mass": 13242.0, "length": 119, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44815", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001285056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285056", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG44815; CG44815; Dmel_CG44815; FBgn0266050", "gene_names_refseq": "CG44815; Dmel\\CG44815; FBgn0266050", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44815-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44815)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JD41-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JEG4-1", "uniprot_id": [ { "id": "X2JEG4_DROME", "url": "https://www.uniprot.org/uniprot/X2JEG4", "type": "external" } ], "mass": 10106.0, "length": 92, "protein_name": "DUF4777 domain-containing protein", "gene_name": "Dmel\\CG45490", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001285471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285471", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG45490; CG45490; Dmel_CG45490", "gene_names_refseq": "CG45490; Dmel\\CG45490", "protein_names_uniprotkb": "DUF4777 domain-containing protein", "protein_names_refseq": "CG45490-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45490)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JEG4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JF29-1", "uniprot_id": [ { "id": "X2JF29_DROME", "url": "https://www.uniprot.org/uniprot/X2JF29", "type": "external" } ], "mass": 20321.0, "length": 177, "protein_name": "Microsomal glutathione S-transferase 1", "gene_name": "CG5579", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001285263", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285263", "type": "external" } ], "gene_names_uniprotkb": "CG5579; BcDNA:RH14671; CG33178; Dmel\\CG33178; Dmel_CG33178", "gene_names_refseq": "BcDNA:RH14671; CG33178; CG5579; Dmel\\CG33178", "protein_names_uniprotkb": "Microsomal glutathione S-transferase 1; 2.5.1.18", "protein_names_refseq": "CG33178-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "ductal carcinoma in situ (Disease Ontology:DOID:0060074); penile benign neoplasm (Disease Ontology:DOID:11624); peptic esophagitis (Disease Ontology:DOID:13976); ovary epithelial cancer (Disease Ontology:DOID:2152); papilloma (Disease Ontology:DOID:2615); transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial adenocarcinoma (Disease Ontology:DOID:2870); endometriosis (Disease Ontology:DOID:289); ischemia (Disease Ontology:DOID:326); lung non-small cell carcinoma (Disease Ontology:DOID:3908); in situ carcinoma (Disease Ontology:DOID:8719); Barrett's esophagus (Disease Ontology:DOID:9206)", "pathway": " (dme:Dmel_CG33178); (R-DME-2162123)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "4.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.5.1.1", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0050220 prostaglandin-E synthase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JF29-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JGJ5-1", "uniprot_id": [ { "id": "X2JGJ5_DROME", "url": "https://www.uniprot.org/uniprot/X2JGJ5", "type": "external" } ], "mass": 7930.0, "length": 68, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG45101", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001287025", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287025", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG45101; CG45101; Dmel_CG45101; Dmel_SuUR_uORF; FBgn0266540", "gene_names_refseq": "CG45101; Dmel\\CG45101; Dmel_SuUR_uORF; FBgn0266540", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG45101-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45101)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JGJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "X2JKA0-1", "uniprot_id": [ { "id": "X2JKA0_DROME", "url": "https://www.uniprot.org/uniprot/X2JKA0", "type": "external" } ], "mass": 30259.0, "length": 281, "protein_name": "Uncharacterized protein", "gene_name": "CG9517", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001285252", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285252", "type": "external" } ], "gene_names_uniprotkb": "CG9517; CG45064; Dmel\\CG45064; Dmel_CG45064; FBgn0266434", "gene_names_refseq": "CG45064; CG9517; Dmel\\CG45064; FBgn0266434", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG45064-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45064)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "X2JKA0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42282-1", "uniprot_id": [ { "id": "TTKA_DROME", "url": "https://www.uniprot.org/uniprot/P42282", "type": "external" } ], "mass": 88383.0, "length": 813, "protein_name": "Protein tramtrack, alpha isoform", "gene_name": "ttk", "organism": "Fruit fly", "refseq_name": "tramtrack, isoform G", "refseq_ac": [ { "id": "NP_001189329", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189329", "type": "external" } ], "gene_names_uniprotkb": "ttk; 04; 05; 06; 07; 08; 10; 14; 15; 16; 17; 25; 31; 3540; 5125; 5311; CG11558; CG1856; Dmel\\CG1856; Dmel_CG1856; E(yan)100D; FTZ-F2; TTK69; TTK88; TTKA; TTK; Tkt69; Tramtrack; Ttk69k; Ttk69; Ttk88; Ttk; anon-EST:Liang-2.9; clone 2.9; ftz-f2; l(3)02667; l(3)j2A1; l(3)j7B8; osn; oss; ovs; tramtrak; ttk69; ttkp69; ttk", "gene_names_refseq": "0037/17; 0250/25; 0438/31; 0702/07; 1049/07; 1119/04; 1184/16; 1209/05; 1209/10; 1260/10; 1281/04; 1325/15; 1372/08; 1396/14; 1418/06; 3540; 5125; 5311; CG11558; CG1856; Dmel\\CG1856; E(yan)100D; FTZ-F2; TTK69; TTK88; TTKA; TTK; Tkt69; Tramtrack; Ttk69k; Ttk69; Ttk88; Ttk; anon-EST:Liang-2.9; clone 2.9; ftz-f2; ftzf2/ttk; l(3)02667; l(3)j2A1; l(3)j7B8; osn; oss; ovs; tramtrak; ttk/FTZ-F2; ttk69; ttkp69; ttk", "protein_names_uniprotkb": "Protein tramtrack, alpha isoform; Repressor protein fushi tarazu; Tramtrack p88", "protein_names_refseq": "CG1856-PG; Tramtrack69; Tramtrack88; Ttk88 repressor; enhancer of yan at 100D; oversensitive; schmal; tramtrack, isoform G; tramtrack-69; tramtrak; ttk-PG", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1856)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10731132;12384587;12537568;12537569;12537572;12537573;12537574;1372245;15306652;16110336;1640455;17569856;17569867;17962185;18160715;18327897;2104801;25589440;26109356;26109357;8223261;8247159;8504931", "class_list": "", "function": "Binds to a number of sites in the transcriptional regulatory region of ftz (PubMed:2104801). Isoform beta is required to repress inappropriate segmentation gene transcription and repress genes incompatible with development of photoreceptor cell fates (PubMed:12384587, PubMed:18160715). Probable repressor of the transcription of the segmentation genes ftz, eve, h, odd, run, and en (PubMed:8223261). Inhibits Trl-dependent activation of eve (PubMed:12384587). May bind to the region AGGGC/TGG (PubMed:8247159). Degradation of ttk is directed by binding of sinah or sina, via the adapter molecule phyl which binds to the BTB domain of ttk (PubMed:17962185, PubMed:18160715). A second method of degradation exists that is phyl-independent, this is mediated by recognition of motifs in the C-terminus of ttk (PubMed:17962185)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Binds to a number of sites in the transcriptional regulatory region of ftz. Isoform alpha is required to repress genes that promote the R7 cell fate. Probable repressor of the transcription of the segmentation genes ftz, eve, h, odd, run, and en. May bind to the region 5'-AGGG[CT]GG-3'. Degradation of ttk is directed by binding of sinah or sina, via the adapter molecule phyl which binds to the BTB domain of ttk., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4V3Q3;Q0KHY0;Q1LZ43;Q24313;Q9V9V2", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0005700 polytene chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0007422 peripheral nervous system development;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P42282-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35832-1", "uniprot_id": [ { "id": "PTP99_DROME", "url": "https://www.uniprot.org/uniprot/P35832", "type": "external" } ], "mass": 145062.0, "length": 1297, "protein_name": "Tyrosine-protein phosphatase 99A", "gene_name": "Ptp99A", "organism": "Fruit fly", "refseq_name": "protein tyrosine phosphatase 99A, isoform B", "refseq_ac": [ { "id": "NP_476816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476816", "type": "external" } ], "gene_names_uniprotkb": "Ptp99A; CG11515; CG11516; CG11517; CG2005; CT6383; DPTP99A; DPTP[[99A]]; Dmel\\CG11516; Dmel_CG11516; Dptp99A; PTP99A; R-PTP 99A; dptp99A; ptp99A", "gene_names_refseq": "CG11515; CG11516; CG11517; CG2005; CT6383; DPTP99A; DPTP[[99A]]; Dmel\\CG11516; Dptp99A; PTP99A; Ptp99A; R-PTP 99A; dptp99A; ptp99A", "protein_names_uniprotkb": "Tyrosine-protein phosphatase 99A; 3.1.3.48; DPTP99A; Receptor-linked protein-tyrosine phosphatase 99A", "protein_names_refseq": "CG11516-PB; Ptp99A-PB; protein tyrosine phosphatase 99A, isoform B", "tax_id": 7227, "disease": "status epilepticus (Disease Ontology:DOID:1824); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); temporal lobe epilepsy (Disease Ontology:DOID:3328); middle cerebral artery infarction (Disease Ontology:DOID:3525); gastric adenocarcinoma (Disease Ontology:DOID:3717)", "pathway": " (dme:Dmel_CG11516)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;1657401;1657402;1662390;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May play a key role in signal transduction and growth control. May have a role in the establishment of the intersegmental and segmental nerves., [UniProtKB, PubMed]", "predicted_glycosites": 11, "predicted_n_glycosites": 6, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "Q59DT5;Q7KRW3;Q8IMK9;Q9VAL3", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0005001 transmembrane receptor protein tyrosine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0031175 neuron projection development;GO:0008045 motor neuron axon guidance;GO:0007414 axonal defasciculation;GO:0007415 defasciculation of motor neuron axon", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P35832-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36958-1", "uniprot_id": [ { "id": "RPB9_DROME", "url": "https://www.uniprot.org/uniprot/P36958", "type": "external" } ], "mass": 15098.0, "length": 129, "protein_name": "DNA-directed RNA polymerase II subunit RPB9", "gene_name": "Polr2I", "organism": "Fruit fly", "refseq_name": "RNA polymerase II subunit I, isoform B", "refseq_ac": [ { "id": "NP_001247099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247099", "type": "external" } ], "gene_names_uniprotkb": "Polr2I; CG3284; Dmel\\CG3284; Dmel_CG3284; H5; Pol II; PolII; RNA Pol II; RNA pol II; RNA polII; RNAP II; RNAP; RNApolII; RPB9; RPII15; RpII15; RpII215; Rpb9; dRPB9; l(3)88Be; l(3)Z23; pol II; polII", "gene_names_refseq": "CG3284; Dmel\\CG3284; H5; Pol II; PolII; Polr2I; RNA Pol II; RNA pol II; RNA polII; RNAP II; RNAP; RNApolII; RPB9; RPII15; RpII15; RpII215; Rpb9; dRPB9; l(3)88Be; l(3)Z23; pol II; polII", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB9; DNA-directed RNA polymerase II 15.1 kDa polypeptide; RNA polymerase II subunit B9; RNA polymerase II subunit I", "protein_names_refseq": "CG3284-PB; Polr2I-PB; RNA pol II; RNA polymerase II 15kd subunit; RNA polymerase II subunit I, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3284); (R-DME-112382); (R-DME-113418); (R-DME-5578749); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-6807505); (R-DME-72086); (R-DME-72163); (R-DME-72165); (R-DME-72203); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075); (R-DME-9018519); (R-DME-9770562)", "pathway_count": 22, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;1545824;16110336;17569856;17569867;25589440;26109356;26109357;8243669", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFK8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005665 RNA polymerase II, core complex;GO:0005654 nucleoplasm;GO:0000428 DNA-directed RNA polymerase complex", "go_biological_process": "GO:0001193 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II;GO:0000278 mitotic cell cycle;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006283 transcription-coupled nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P36958-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47947-1", "uniprot_id": [ { "id": "TNNC1_DROME", "url": "https://www.uniprot.org/uniprot/P47947", "type": "external" } ], "mass": 17156.0, "length": 154, "protein_name": "Troponin C, isoform 1", "gene_name": "TpnC41C", "organism": "Fruit fly", "refseq_name": "troponin C at 41C, isoform B", "refseq_ac": [ { "id": "NP_001246139", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246139", "type": "external" } ], "gene_names_uniprotkb": "TpnC41C; CG2981; DmTnC1; DmTpnC41C; DmTpnCIIIa; Dmel\\CG2981; Dmel_CG2981; TNC41C; TPNC; TPnC41C; TnC1; TnC41C; TnC; Tnc1; TpnC IIIa; TpnC41; TpnC4; TpnCIIIa", "gene_names_refseq": "CG2981; DmTnC1; DmTpnC41C; DmTpnCIIIa; Dmel\\CG2981; TNC41C; TPNC; TPnC41C; TnC1; TnC41C; TnC; Tnc1; TpnC IIIa; TpnC41C; TpnC41; TpnC4; TpnCIIIa", "protein_names_uniprotkb": "Troponin C, isoform 1", "protein_names_refseq": "CG2981-PB; TpnC41C-PB; TroponinC at 41C; troponin C at 41C, isoform B; troponin C; troponin-C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2981); (R-DME-111932); (R-DME-111933); (R-DME-111957); (R-DME-114608); (R-DME-1474151); (R-DME-163615); (R-DME-1855204); (R-DME-2025928); (R-DME-203615); (R-DME-2514859); (R-DME-2871809); (R-DME-4086398); (R-DME-418359); (R-DME-425561); (R-DME-438066); (R-DME-442729); (R-DME-451308); (R-DME-5218920); (R-DME-5578775); (R-DME-5607763); (R-DME-5673000); (R-DME-70221); (R-DME-8876725); (R-DME-9009391); (R-DME-936837); (R-DME-9619229); (R-DME-9648002); (R-DME-9856530)", "pathway_count": 29, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7980384", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V9E1", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P47947-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZAJ2-1", "uniprot_id": [ { "id": "KIF1A_DROME", "url": "https://www.uniprot.org/uniprot/A1ZAJ2", "type": "external" } ], "mass": 189345.0, "length": 1670, "protein_name": "Kinesin-like protein unc-104", "gene_name": "unc-104", "organism": "Fruit fly", "refseq_name": "uncoordinated-104, isoform E", "refseq_ac": [ { "id": "NP_001097346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097346", "type": "external" } ], "gene_names_uniprotkb": "unc-104; 1B; CG8566; DUNC104; DUnc-104; DmCG8566; DmDUnc104; DmKlp53D; Dmel\\CG8566; Dmel_CG8566; Dunc104; Imac; KIF 1B; KIF1A; Kif1a; Klp53D; Unc-104; Unc104; bris; imac; kif1a; unc104", "gene_names_refseq": "CG8566; DUNC104; DUnc-104; DmCG8566; DmDUnc104; DmKlp53D; Dmel\\CG8566; Dunc104; Imac; KIF 1B; KIF1A/1B; KIF1A; Kif1a; Klp53D; Unc-104; Unc104; bris; imac; kif1a; unc-104; unc104", "protein_names_uniprotkb": "Kinesin-like protein unc-104; DUnc104; Protein immaculate connections", "protein_names_refseq": "CG8566-PE; D uncoordinated protein 104; Kinesin4B; bristly; immaculate connections; kinesin 3; kinesin-3; unc-104 ortholog; unc-104-PE; uncoordinated 104; uncoordinated-104, isoform E", "tax_id": 7227, "disease": "hereditary sensory and autonomic neuropathy (Disease Ontology:DOID:0050548); synucleinopathy (Disease Ontology:DOID:0050890); spastic ataxia 2 (Disease Ontology:DOID:0050941); NESCAV syndrome (Disease Ontology:DOID:0070039); hereditary sensory neuropathy type 2C (Disease Ontology:DOID:0070147); hereditary spastic paraplegia 30B (Disease Ontology:DOID:0070646); hereditary spastic paraplegia 30A (Disease Ontology:DOID:0070647); Graves ophthalmopathy (Disease Ontology:DOID:0081120); Charcot-Marie-Tooth disease type 2A1 (Disease Ontology:DOID:0110154); hereditary spastic paraplegia 30 (Disease Ontology:DOID:0110781); ovary epithelial cancer (Disease Ontology:DOID:2152); multiple sclerosis (Disease Ontology:DOID:2377); hereditary spastic paraplegia (Disease Ontology:DOID:2476); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); hepatocellular carcinoma (Disease Ontology:DOID:684); neuroblastoma (Disease Ontology:DOID:769); nervous system disease (Disease Ontology:DOID:863)", "pathway": " (dme:Dmel_CG8566)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;17643120;18327897;25589440;26109356;26109357;30174114", "class_list": "", "function": "Required for presynaptic maturation, has a role in axonal transport of dense-core vesicles carrying synaptic vesicle precursors, components required for the morphological transformation of axonal growth cones to mature boutons., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8DX00;A8DYG5;Q9NBL1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0030742 GTP-dependent protein binding;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0030424 axon;GO:0030425 dendrite;GO:0043679 axon terminus", "go_biological_process": "GO:0007528 neuromuscular junction development;GO:0008088 axo-dendritic transport;GO:0015031 protein transport;GO:0032024 positive regulation of insulin secretion;GO:0040012 regulation of locomotion", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A1ZAJ2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P13469-1", "uniprot_id": [ { "id": "MODU_DROME", "url": "https://www.uniprot.org/uniprot/P13469", "type": "external" } ], "mass": 60310.0, "length": 542, "protein_name": "DNA-binding protein modulo", "gene_name": "mod", "organism": "Fruit fly", "refseq_name": "modulo, isoform C", "refseq_ac": [ { "id": "NP_001247401", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247401", "type": "external" } ], "gene_names_uniprotkb": "mod; 14; CG2050; Dmel\\CG2050; Dmel_CG2050; Modulo; Mod; ms(3)100EF", "gene_names_refseq": "0952/14; CG2050; Dmel\\CG2050; Modulo; Mod; mod; ms(3)100EF", "protein_names_uniprotkb": "DNA-binding protein modulo", "protein_names_refseq": "CG2050-PC; male sterile(3)100EF; mod-PC; modulo, isoform C; modulo", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2050)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;18327897;2510126;25589440;26109356;26109357;7813788", "class_list": "", "function": "Its capacity to bind DNA and protein(s), and its differential expression during development suggest a role in the regulation of gene expression during Drosophila development. It could, in interaction with other factors, be required for the translation of instructions provided by pattern forming genes and controls, via chromatin changes, the activity of genes critical for the process of morphogenesis of several embryonic territories., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V9S2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0043565 sequence-specific DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P13469-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4K7J2-1", "uniprot_id": [ { "id": "RBP2_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4K7J2", "type": "external" } ], "mass": 298931.0, "length": 2718, "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Nup358", "organism": "Fruit fly", "refseq_name": "nucleoporin 358kD, isoform B", "refseq_ac": [ { "id": "NP_001247302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247302", "type": "external" } ], "gene_names_uniprotkb": "Nup358; CG11856; RanBP2", "gene_names_refseq": "CG11856; Dmel\\CG11856; NUP358; Nup358; Q9VBU7_DROME; RanBP2; dmRanBP; nup358; ranbp2", "protein_names_uniprotkb": "E3 SUMO-protein ligase RanBP2; 2.3.2.-; 358 kDa nucleoporin; Nuclear pore complex protein Nup358", "protein_names_refseq": "CG11856-PB; Nup358-PB; nucleoporin 358kD, isoform B; nucleoporin 358", "tax_id": 7227, "disease": "inflammatory myofibroblastic tumor (Disease Ontology:DOID:0050905); brain disease (Disease Ontology:DOID:936); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (dme:Dmel_CG11856); (R-DME-159227); (R-DME-159230); (R-DME-159231); (R-DME-159236); (R-DME-1855170); (R-DME-1855196); (R-DME-1855229); (R-DME-3108214); (R-DME-3301854); (R-DME-3371453); (R-DME-4085377); (R-DME-4551638); (R-DME-4615885)", "pathway_count": 14, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;14729961;17682050;20547758;27979731;29735528;31626769;40245499", "class_list": "", "function": "E3 SUMO-protein ligase (By similarity). Component of the nuclear pore complex (NPC), a complex required for trafficking across the nuclear envelope (PubMed:17682050). Required for nuclear import of nuclear localization signal (NLS)-containing proteins in an importin alpha/importin beta-dependent manner, but also for the nuclear import of specific proteins such as phosphorylated Mad or the sesquiterpenoid juvenile hormone receptor Met as part of the juvenile hormone signal transduction pathway (PubMed:17682050, PubMed:27979731). Plays a role in nuclear mRNA export by recruiting the mRNA transport complex composed of Nxt1 and sbr/Nxf1 to the NPC (PubMed:14729961). Essential during germline development for transposon silencing and piRNA biogenesis probably by regulating piwi localization to the nucleus (PubMed:29735528). During oogenesis, required to form granules that modulate the biogenesis of annulate lamellae containing nuclear pore complex components (PubMed:31626769)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D3DMF2;Q8SWV7;Q9VBU7", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0019789 SUMO transferase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005642 annulate lamellae", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0006913 nucleocytoplasmic transport;GO:0010628 positive regulation of gene expression;GO:0007281 germ cell development;GO:0051168 nuclear export", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "A0A0B4K7J2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16844-1", "uniprot_id": [ { "id": "COS_DROME", "url": "https://www.uniprot.org/uniprot/O16844", "type": "external" } ], "mass": 133148.0, "length": 1201, "protein_name": "Kinesin-like protein costa", "gene_name": "cos", "organism": "Fruit fly", "refseq_name": "costa, isoform B", "refseq_ac": [ { "id": "NP_001260765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260765", "type": "external" } ], "gene_names_uniprotkb": "cos; 28; B; CG1708; COS2; COS[2]; Cos-2; Cos2; Cos[2]; Costal2; Cos; DmCos2; Dmel\\CG1708; Dmel_CG1708; Kif7; cos-2; cos2; costal-2; l(2)cos[[2]]; l(2)k16101; l(2)k16128", "gene_names_refseq": "CG1708; COS2; COS[2]; Cos-2; Cos2; Cos[2]; Costal2; Cos; DmCos2; Dmel\\CG1708; KIF26A/B; Kif7; cos-2; cos2; cos; l(2)161/28; l(2)cos[[2]]; l(2)k16101; l(2)k16128", "protein_names_uniprotkb": "Kinesin-like protein costa; Kinesin-like protein costal2", "protein_names_refseq": "CG1708-PB; Costal-2; DmCostal2; Kinesin_B; cos-PB; costa, isoform B; costal 2; costal2; costa; enhancer of epaulette", "tax_id": 7227, "disease": "hydrolethalus syndrome (Disease Ontology:DOID:0050779); idiopathic scoliosis (Disease Ontology:DOID:0060250); ciliopathy (Disease Ontology:DOID:0060340); hydrocephalus (Disease Ontology:DOID:10908); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); acrocallosal syndrome (Disease Ontology:DOID:9250)", "pathway": " (dme:Dmel_CG1708); (R-DME-209159); (R-DME-209190); (R-DME-209214); (R-DME-209338); (R-DME-209360); (R-DME-216119); (R-DME-216217)", "pathway_count": 8, "publication_count": 74, "publication_id_list": "10102270;10409506;10458606;10477300;10529426;10557210;10731132;10825151;10862738;10862750;10952898;10966113;11090136;11495917;11912487;11914126;11934882;11955435;11997517;12231619;12537568;12537569;12537572;12537573;12537574;12663920;14523402;14597665;14614827;14636583;15063184;15300262;15563523;15592457;15598741;15616566;15691767;15750186;15875013;16041759;16110336;16299518;16326393;16386907;16630821;17077139;17182028;17569856;17569867;17671093;17881487;17925225;17960137;18211840;18327897;20435030;25589440;25633354;25639794;26109356;26109357;27195754;32467643;8769644;8898207;8906787;8906794;9109493;9122207;9215627;9244298;9431812;9482888;9601642", "class_list": "", "function": "Regulates cubitus interruptus (ci) processing by recruiting multiple kinases to promote its efficient phosphorylation. Scaffolds multiple kinases and ci into proximity to promote its hyperphosphorylation, which then targets it for SCFSlimb/proteasome-mediated processing to generate its repressor form. Hh signaling inhibits ci phosphorylation by interfering with the cos-ci-kinases complex formation. Negatively regulates hh-signaling pathways during various processes, including photoreceptor differentiation (PubMed:25639794, PubMed:27195754). May negatively regulate a hh-signaling pathway which functions in the intestinal immune response to bacterial uracil by activating the Duox-dependent production of reactive oxygen species (ROS) (PubMed:25639794)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1Z6X4;B5RIP3;Q6AWI9;Q8IH04", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0019901 protein kinase binding;GO:0016887 ATP hydrolysis activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule;GO:0005929 cilium;GO:0005871 kinesin complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042981 regulation of apoptotic process;GO:0007018 microtubule-based movement;GO:0007224 smoothened signaling pathway;GO:0042073 intraciliary transport", "synthesized_glycan_count": 0, "hit_score": 7.5, "record_id": "O16844-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P29310-1", "uniprot_id": [ { "id": "1433Z_DROME", "url": "https://www.uniprot.org/uniprot/P29310", "type": "external" } ], "mass": 28228.0, "length": 248, "protein_name": "14-3-3 protein zeta", "gene_name": "14-3-3zeta", "organism": "Fruit fly", "refseq_name": "14-3-3zeta, isoform J", "refseq_ac": [ { "id": "NP_001014515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014515", "type": "external" } ], "gene_names_uniprotkb": "14-3-3zeta; 14-3-3 zeta; 14-3-3-Leo; 14-3-3-zeta; 14-3-3EZ; 14-3-3ZETA; 14-3-3leo; 14-3-3z; 14-3-3; 14.3.3; 1433Z; 2G1; 4-3-3 zeta; 5.11; 549; BEST:GH05075; CG17870; D14-3-3zeta; D14-3-3; Dmel\\CG17870; Dmel_CG17870; K; LEO; Leo; PAR-5; PAR5; Par-5; THAP; d14-3-3zeta; l(2)07103; l(2)46CFe; l(2)46Ee; leo; par-5", "gene_names_refseq": "14-3-3 zeta; 14-3-3-Leo; 14-3-3-zeta; 14-3-3ZETA; 14-3-3leo; 14-3-3zeta; 14-3-3z; 14-3-3; 14.3.3; 1433Z; 2G1; 4-3-3 zeta; 5.11; 549; BEST:GH05075; CG17870; D14-3-3zeta; D14-3-3; Dmel\\CG17870; K; LEO; Leo; PAR-5; PAR5; Par-5; d14-3-3zeta; l(2)07103; l(2)46CFe; l(2)46Ee; leo; par-5", "protein_names_uniprotkb": "14-3-3 protein zeta; 14-3-3-like protein; Protein Leonardo", "protein_names_refseq": "14-3-3zeta, isoform J; 14-3-3zeta-PJ; CG17870-PJ; D14 3 3 protein; Leonardo-13-3-3; complementation group K; leonardo 14-3-3; leonardo", "tax_id": 7227, "disease": "absence epilepsy (Disease Ontology:DOID:0070309); developmental and epileptic encephalopathy 56 (Disease Ontology:DOID:0080282); intellectual disability (Disease Ontology:DOID:1059); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); Creutzfeldt-Jakob disease (Disease Ontology:DOID:11949); vulva squamous cell carcinoma (Disease Ontology:DOID:2101); brain ischemia (Disease Ontology:DOID:2316); ovarian cancer (Disease Ontology:DOID:2394); transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial carcinoma (Disease Ontology:DOID:2871); temporal lobe epilepsy (Disease Ontology:DOID:3328); schizophrenia (Disease Ontology:DOID:5419); hepatocellular carcinoma (Disease Ontology:DOID:684); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (dme:Dmel_CG17870); (R-DME-165159); (R-DME-170968); (R-DME-2028269); (R-DME-3769402); (R-DME-390098); (R-DME-392517); (R-DME-430116); (R-DME-450385); (R-DME-450513); (R-DME-450604); (R-DME-5625740); (R-DME-5628897); (R-DME-5673000); (R-DME-5674135); (R-DME-5675221); (R-DME-6804114); (R-DME-75035); (R-DME-9013700); (R-DME-9614399); (R-DME-9929491)", "pathway_count": 21, "publication_count": 24, "publication_id_list": "10230800;10731132;12529354;12537568;12537569;12537572;12537573;12537574;1349290;16096061;16110336;17569856;17569867;17889654;18256197;19330023;19733165;19900439;25589440;25920570;26109356;26109357;27015288;9159395", "class_list": "", "function": "Required in Raf-dependent cell proliferation and photoreceptor differentiation during eye development (PubMed:9159395). Acts upstream of Raf and downstream of Ras, and is essential for viability (PubMed:9159395). Acts as a negative regulator of the slo calcium channel via its interaction with slo-binding protein slob (PubMed:10230800). Inhibits yki activity by restricting its nuclear localization (PubMed:19900439). Binds to and promotes the activity of phosphoinositide 3-kinase Pi3K68D which converts phosphatidylinositol to phosphatidylinositol-3-phosphate and promotes maturation of early endosomes (PubMed:27015288)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZB2;A4UZB3;C1C593;C9QP27;O01665;Q0E9D5;Q0E9D6;Q0E9D7;Q8IGB9;Q8MKV5;Q9V5G6", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0001223 transcription coactivator binding;GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005829 cytosol", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0007059 chromosome segregation;GO:0007165 signal transduction;GO:0007611 learning or memory;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P29310-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25172-1", "uniprot_id": [ { "id": "SUZ2_DROME", "url": "https://www.uniprot.org/uniprot/P25172", "type": "external" } ], "mass": 146393.0, "length": 1368, "protein_name": "Protein suppressor 2 of zeste", "gene_name": "Su(z)2", "organism": "Fruit fly", "refseq_name": "suppressor of zeste 2, isoform B", "refseq_ac": [ { "id": "NP_001163134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163134", "type": "external" } ], "gene_names_uniprotkb": "Su(z)2; Arp; CG3905; Dmel\\CG3905; Dmel_CG3905; SU(Z)2; SUZ2; Su(Z)2; Su(z)2D; Su(z)3; Su(z)[[2]]; Suz2; l(2)k06344; su(z)2; su(z)3", "gene_names_refseq": "Arp; CG3905; Dmel\\CG3905; SU(Z)2; SUZ2; Su(Z)2; Su(z)2D; Su(z)2; Su(z)3; Su(z)[[2]]; Suz2; l(2)k06344; su(z)2; su(z)3", "protein_names_uniprotkb": "Protein suppressor 2 of zeste; Protein posterior sex combs", "protein_names_refseq": "CG3905-PB; Su(z)2-PB; aristapedioid; aristopedoid; suppressor 2 of zeste; suppressor of zeste (2); suppressor of zeste (3); suppressor of zeste 2, isoform B; suppressor of zeste 3; suppressor of zeste two; suppressor two of zeste; supressor of zeste 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3905)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;2057369;25589440;26109356;26109357;33925313", "class_list": "", "function": "Regulates expression of the homeotic selector genes by influencing higher-order chromatin structure through interaction with other proteins., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q9V6J0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0035102 PRC1 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0031507 heterochromatin formation;GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P25172-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40791-1", "uniprot_id": [ { "id": "MEF2_DROME", "url": "https://www.uniprot.org/uniprot/P40791", "type": "external" } ], "mass": 57172.0, "length": 540, "protein_name": "Myocyte-specific enhancer factor 2", "gene_name": "Mef2", "organism": "Fruit fly", "refseq_name": "myocyte enhancer factor 2, isoform C", "refseq_ac": [ { "id": "NP_477018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477018", "type": "external" } ], "gene_names_uniprotkb": "Mef2; 22.21; BEST:SD04091; CG1429; C; D-MEF2; D-Mef2; D-mef2; DMEF-2; DMEF2; DMedf2; DMef-2; DMef2; Dmef-2; Dmef2; Dmef; Dmel\\CG1429; Dmel_CG1429; MEF-2; MEF2; Mef-2; Mef; SD04091; dMEF2; dMEf2; dMef2; dmef2; l(2)46CFr; mb247; mef-2; mef2c; mef2; mef", "gene_names_refseq": "22.21; BEST:SD04091; CG1429; C; D-MEF2; D-Mef2; D-mef2; DMEF-2; DMEF2; DMedf2; DMef-2; DMef2; Dmef-2; Dmef2; Dmef; Dmel\\CG1429; MEF-2; MEF2; Mef-2; Mef2; Mef; SD04091; dMEF2; dMEf2; dMef2; dmef2; l(2)46CFr; mb247; mef-2; mef2c; mef2; mef", "protein_names_uniprotkb": "Myocyte-specific enhancer factor 2; D-mef2; MADS domain transcription factor", "protein_names_refseq": "CG1429-PC; DMEF2; Drosophila-myocyte enhancer factor 2; Mef2-PC; Myocyte-enhancer factor 2; Myocyte-enhancer factor-2; complementation group C; drosophila myocyte-specific enhancer factor 2; myocyte enhancer factor 2, isoform C; myocyte enhancer factor-2; myocyte enhancing factor 2; myocyte-specific enhancer factor 2", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language (Disease Ontology:DOID:0070050); intellectual disability (Disease Ontology:DOID:1059); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); dilated cardiomyopathy (Disease Ontology:DOID:12930); lung cancer (Disease Ontology:DOID:1324); status epilepticus (Disease Ontology:DOID:1824); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG1429); (R-DME-525793)", "pathway_count": 2, "publication_count": 20, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;24075010;25589440;25797154;26109356;26109357;40245499;7605749;7839146;8052612;8202544", "class_list": "", "function": "Transcription factor that could be a key player in early mesoderm differentiation and may be required for subsequent cell fate specifications within the somatic and visceral/heart mesodermal layers (PubMed:7839146, PubMed:8052612, PubMed:8202544). Essential for myoblast fusion and consequently muscle formation in adults (PubMed:25797154). During embryonic and pupal development, binds to the enhancer of the myoblast fusion gene sing and activates its transcription (PubMed:25797154)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A1Z821;Q24394;Q8MT88;Q95R70;Q95RW1;Q9U5I8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0042826 histone deacetylase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P40791-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B4KEQ7-1", "uniprot_id": [ { "id": "A0A0B4KEQ7_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B4KEQ7", "type": "external" } ], "mass": 59620.0, "length": 530, "protein_name": "Regulatory protein zeste", "gene_name": "Dmel\\CG10209", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": [ { "id": "NP_001260982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260982", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10209; CG10209; Dmel_CG10209", "gene_names_refseq": "CG10209; Dmel\\CG10209", "protein_names_uniprotkb": "Regulatory protein zeste", "protein_names_refseq": "CG10209-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10209)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KEQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P24014-1", "uniprot_id": [ { "id": "SLIT_DROME", "url": "https://www.uniprot.org/uniprot/P24014", "type": "external" } ], "mass": 168599.0, "length": 1504, "protein_name": "Protein slit", "gene_name": "sli", "organism": "Fruit fly", "refseq_name": "slit, isoform D", "refseq_ac": [ { "id": "NP_001097333", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097333", "type": "external" } ], "gene_names_uniprotkb": "sli; CG33464; CG43758; CG8355; CT21700; CT37068; Dmel\\CG43758; Dmel_CG43758; Slit; Sli; dSlit; fus3; l(2)05248; wdh", "gene_names_refseq": "CG33464; CG43758; CG8355; CT21700; CT37068; Dmel\\CG43758; Slit; Sli; dSlit; fus3; l(2)05248; sli; wdh", "protein_names_uniprotkb": "Protein slit; Slit-FL; dSlit", "protein_names_refseq": "CG43758-PD; SGP cluster fusion defects 3; lethal (2) 05248; sli-PD; slit, isoform D; slit", "tax_id": 7227, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); small intestine carcinoid neuroendocrine tumor (Disease Ontology:DOID:0050925); atrial fibrillation (Disease Ontology:DOID:0060224); polymyositis (Disease Ontology:DOID:0080745); dermatomyositis (Disease Ontology:DOID:10223); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); transient cerebral ischemia (Disease Ontology:DOID:224); cystic kidney disease (Disease Ontology:DOID:2975); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); diabetic retinopathy (Disease Ontology:DOID:8947); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG43758); (R-DME-376176); (R-DME-428890); (R-DME-9010553)", "pathway_count": 4, "publication_count": 17, "publication_id_list": "10102267;10102268;10731132;12537568;12537572;12537573;12537574;15496984;16110336;17569856;17569867;2176636;25589440;26109356;26109357;3144436;32994163", "class_list": "", "function": "A short-range repellent, controlling axon crossing of the midline and a long-range chemorepellent, controlling mesoderm migration and patterning away from the midline. May interact with extracellular matrix molecules. Repulsive ligand for the guidance receptor roundabout (robo) and prevents inappropriate midline crossing by Robo-expressing axons., [UniProtKB, PubMed, PubMed, PubMed, PubMed]; Promotes longitudinal axon growth., [UniProtKB, PubMed]; Promotes midline repulsion of axons but not longitudinal axon guidance., [UniProtKB, PubMed]", "predicted_glycosites": 13, "predicted_n_glycosites": 13, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "A8DYF5;A8DYF6;Q24526;Q8MLB9;Q9V7F8;Q9V7F9;Q9XYV4", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0005509 calcium ion binding;GO:0048495 Roundabout binding;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030424 axon;GO:0071666 Slit-Robo signaling complex", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0050929 induction of negative chemotaxis;GO:0016199 axon midline choice point recognition;GO:0030335 positive regulation of cell migration;GO:0001764 neuron migration", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P24014-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O15945-1", "uniprot_id": [ { "id": "ARNT_DROME", "url": "https://www.uniprot.org/uniprot/O15945", "type": "external" } ], "mass": 71475.0, "length": 642, "protein_name": "Aryl hydrocarbon receptor nuclear translocator homolog", "gene_name": "tgo", "organism": "Fruit fly", "refseq_name": "tango, isoform B", "refseq_ac": [ { "id": "NP_001262397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262397", "type": "external" } ], "gene_names_uniprotkb": "tgo; ARNT; Arnt; CG11987; DARNT; Dmel\\CG11987; Dmel_CG11987; HIF-1-beta; HIF-1beta; HIF-1b; HIF-1; HIF1B; HIF1b; HIF1; Hif1; TGO_CYC; TGO; Tango; Tgo; arnt; bHLHe4; dARNT; dHIF-1beta; dTgo; darnt; jay; prd7", "gene_names_refseq": "ARNT; Arnt; CG11987; DARNT; Dmel\\CG11987; HIF-1beta; HIF-1b; HIF-1; HIF1B/ARNT; HIF1B; HIF1b; HIF1; Hif1; TGO_CYC; TGO; Tango; Tgo; arnt; bHLHe4; dARNT; dHIF-1beta; dTgo; darnt; jay; prd7; tgo/Arnt; tgo", "protein_names_uniprotkb": "Aryl hydrocarbon receptor nuclear translocator homolog; Hypoxia-inducible factor 1-beta; Protein tango; dARNT", "protein_names_refseq": "CG11987-PB; PRD gene 7; jaywalker; paired-like 7; tango, isoform B; tango; tgo-PB", "tax_id": 7227, "disease": "hypertension (Disease Ontology:DOID:10763); renal cell carcinoma (Disease Ontology:DOID:4450); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG11987); (R-DME-1234158); (R-DME-211945); (R-DME-8937144); (R-DME-9768919)", "pathway_count": 5, "publication_count": 17, "publication_id_list": "10581393;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;2877746;9284047;9374395;9409674", "class_list": "", "function": "Heterodimers of tgo/trh are involved in the control of breathless expression. Plays a role in the cellular or tissue response to oxygen deprivation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O16167;O44082;Q24461;Q9VHI2", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046982 protein heterodimerization activity;GO:0017022 myosin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034751 aryl hydrocarbon receptor complex;GO:0090575 RNA polymerase II transcription regulator complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0032869 cellular response to insulin stimulus;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "O15945-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46036-1", "uniprot_id": [ { "id": "CTBP_DROME", "url": "https://www.uniprot.org/uniprot/O46036", "type": "external" } ], "mass": 50737.0, "length": 476, "protein_name": "C-terminal-binding protein", "gene_name": "CtBP", "organism": "Fruit fly", "refseq_name": "C-terminal binding protein, isoform E", "refseq_ac": [ { "id": "NP_001014617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014617", "type": "external" } ], "gene_names_uniprotkb": "CtBP; 16; BcDNA:GH07572; CG7583; CTBP; Dm-CtBP; Dmel\\CG7583; Dmel_CG7583; EP(3)3528; G9; RE01030; RE61183; ctbp; dCtBP; l(3)03463; l(3)03464; l(3)87DE; l(3)87De; l(3)G9", "gene_names_refseq": "0256/16; 256/16; BcDNA:GH07572; CG7583; CTBP; CtBP; Dm-CtBP; Dmel\\CG7583; EP(3)3528; G9; RE01030; RE61183; ctbp; dCtBP; l(3)03463; l(3)03464; l(3)87DE; l(3)87De; l(3)G9", "protein_names_uniprotkb": "C-terminal-binding protein; CtBP protein; dCtBP", "protein_names_refseq": "C-terminal binding protein, isoform E; C-terminal binding protein; C-terminal-Binding-Protein; C-terminal-binding protein; CG7583-PE; CtBP-PE; drosophila C-terminal binding protein; lethal(3)87De", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (dme:Dmel_CG7583); (R-DME-3769402); (R-DME-3899300); (R-DME-4641265); (R-DME-9764725)", "pathway_count": 5, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9524128;9525852", "class_list": "", "function": "Corepressor targeting diverse transcription regulators. Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O61283;Q59DX5;Q95SQ8;Q9VG02", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0003714 transcription corepressor activity;GO:0051287 NAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0031010 ISWI-type complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "O46036-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P05709-1", "uniprot_id": [ { "id": "SIM_DROME", "url": "https://www.uniprot.org/uniprot/P05709", "type": "external" } ], "mass": 75665.0, "length": 688, "protein_name": "Protein single-minded", "gene_name": "sim", "organism": "Fruit fly", "refseq_name": "single-minded, isoform A", "refseq_ac": [ { "id": "NP_524340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524340", "type": "external" } ], "gene_names_uniprotkb": "sim; 02; 04; 08; 09; 10; 13; 14; CG7771; Dmel\\CG7771; Dmel_CG7771; S8; SIM; Sim; bHLHe16; l(3)87Ea; l(3)E320; l(3)RD; l(3)S8; l(3)s8; schm; shm", "gene_names_refseq": "0483/09; 0716/08; 0899/14; 0953/08; 1002/10; 1034/02; 1050/13; 1110/04; 1111/10; 1330/08; 1479/04; CG7771; Dmel\\CG7771; S8; SIM; Sim; bHLHe16; l(3)87Ea; l(3)E320; l(3)RD; l(3)S8; l(3)s8; schm; shm; sim", "protein_names_uniprotkb": "Protein single-minded", "protein_names_refseq": "CG7771-PA; Single-minded; Singled-minded; schmal; sim-PA; single minded; single-minded, isoform A; singleminded", "tax_id": 7227, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG7771)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;12221007;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;1760843;23644463;25589440;26109356;26109357;3345560;9840810", "class_list": "", "function": "Transcription factor that functions as a master developmental regulator controlling midline development of the ventral nerve cord (PubMed:12221007, PubMed:1760843, PubMed:9840810). Required to correctly specify the formation of the central brain complex, which controls walking behavior (PubMed:12221007, PubMed:1760843, PubMed:9840810). Also required for correct patterning of the embryonic genital disk and anal pad anlage (PubMed:12221007, PubMed:1760843, PubMed:9840810). Plays a role in synapse development (PubMed:23644463)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O96521;Q7KSL7;Q8MQI7;Q9VFZ3", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046982 protein heterodimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0007418 ventral midline development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007409 axonogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P05709-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T045-1", "uniprot_id": [ { "id": "RUMI_DROME", "url": "https://www.uniprot.org/uniprot/Q8T045", "type": "external" } ], "mass": 47735.0, "length": 411, "protein_name": "O-glucosyltransferase rumi", "gene_name": "rumi", "organism": "Fruit fly", "refseq_name": "rumi, isoform A", "refseq_ac": [ { "id": "NP_651095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651095", "type": "external" } ], "gene_names_uniprotkb": "rumi; CG17138; CG31152; Dmel\\CG31152; Dmel_CG31152; Poglut1; Rumi; dRumi", "gene_names_refseq": "CG17138; CG31152; Dmel\\CG31152; Poglut1; Rumi; dRumi; rumi", "protein_names_uniprotkb": "O-glucosyltransferase rumi; 2.4.1.-", "protein_names_refseq": "CG31152-PA; rumi, isoform A; rumi-PA", "tax_id": 7227, "disease": "Dowling-Degos disease (Disease Ontology:DOID:0060256); autosomal recessive limb-girdle muscular dystrophy type 2Z (Disease Ontology:DOID:0080762); autosomal recessive limb-girdle muscular dystrophy (Disease Ontology:DOID:0110274)", "pathway": " (dme:Dmel_CG31152)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18243100;25589440;26109356;26109357;27428513;27807076", "class_list": "glycogene;glycosyltransferase", "function": "Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue found in the consensus sequence C-X-S-X-[PA]-C in epidermal growth factor-like repeats (PubMed:27428513). Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 17, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046527 glucosyltransferase activity;GO:0035252 UDP-xylosyltransferase activity;GO:0035251 UDP-glucosyltransferase activity;GO:0140561 EGF-domain serine glucosyltransferase activity;GO:0140562 EGF-domain serine xylosyltransferase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen;GO:0012505 endomembrane system", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0006493 protein O-linked glycosylation;GO:0045747 positive regulation of Notch signaling pathway;GO:0045746 negative regulation of Notch signaling pathway;GO:0060537 muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q8T045-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09491-1", "uniprot_id": [ { "id": "TPM2_DROME", "url": "https://www.uniprot.org/uniprot/P09491", "type": "external" } ], "mass": 32981.0, "length": 284, "protein_name": "Tropomyosin-2", "gene_name": "Tm2", "organism": "Fruit fly", "refseq_name": "tropomyosin 2, isoform F", "refseq_ac": [ { "id": "NP_001262592", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262592", "type": "external" } ], "gene_names_uniprotkb": "Tm2; CG4843; DROTROPI1; Dmel\\CG4843; Dmel_CG4843; IP16005p; Ifm(3)3; Ifm(3)5; Ifm-TmI; TM2; Tm127; TmII; TmI; Tm; Tn-H; dro Tm; l(3)nc99Eb; mTmI", "gene_names_refseq": "CG4843; DROTROPI1; Dmel\\CG4843; IP16005p; Ifm(3)3; Ifm(3)5; Ifm-TmI; TM2; Tm127; Tm2; TmII; TmI; Tm; Tn-H; dro Tm; l(3)nc99Eb; mTmI", "protein_names_uniprotkb": "Tropomyosin-2; Tropomyosin I", "protein_names_refseq": "CG4843-PF; Tm2-PF; Tropomyosin-2; lethal(3)nc99Eb; tropomyosin 127; tropomyosin 2, isoform F; tropomyosin I; tropomyosin2", "tax_id": 7227, "disease": "congenital myopathy 4A (Disease Ontology:DOID:0080102); familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326); hypertrophic cardiomyopathy 3 (Disease Ontology:DOID:0110309); dilated cardiomyopathy 1Y (Disease Ontology:DOID:0110457); congenital myopathy 4B (Disease Ontology:DOID:0110926); congenital myopathy 23 (Disease Ontology:DOID:0110932); distal arthrogryposis type 1A (Disease Ontology:DOID:0111597); dilated cardiomyopathy (Disease Ontology:DOID:12930); blood platelet disease (Disease Ontology:DOID:2218); papillary thyroid carcinoma (Disease Ontology:DOID:3969)", "pathway": " (dme:Dmel_CG4843); (R-DME-445355); (R-DME-9013424)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;19567471;25589440;26109356;26109357;3079761;4000944;6202423", "class_list": "", "function": "Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AVW5;A4V2Y6;P09490;Q24408;Q24427;Q24428;Q8SZ65;Q9VF95", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005884 actin filament", "go_biological_process": "GO:0006936 muscle contraction;GO:0007015 actin filament organization;GO:0007507 heart development;GO:0060298 positive regulation of sarcomere organization;GO:0048731 system development", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P09491-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48461-1", "uniprot_id": [ { "id": "PP11_DROME", "url": "https://www.uniprot.org/uniprot/P48461", "type": "external" } ], "mass": 37370.0, "length": 327, "protein_name": "Serine/threonine-protein phosphatase alpha-1 isoform", "gene_name": "Pp1alpha-96A", "organism": "Fruit fly", "refseq_name": "protein phosphatase 1alpha at 96A, isoform B", "refseq_ac": [ { "id": "NP_001262919", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262919", "type": "external" } ], "gene_names_uniprotkb": "Pp1alpha-96A; 96A; CG6593; DmPp1-96A; Dmel\\CG6593; Dmel_CG6593; PP1 96A; PP1 alpha96a; PP1-96A; PP1A-96A; PP1alpha-96A; PP1alpha96A; PP1alpha[[1]]; PP1alpha; PP1c 96A; PP1c; PP1; Pp1-96A; pp1alpha-96A; pp1alpha96A", "gene_names_refseq": "96A; CG6593; DmPp1-96A; Dmel\\CG6593; PP1 96A; PP1 alpha96a; PP1-96A; PP1A-96A; PP1alpha-96A; PP1alpha96A; PP1alpha[[1]]; PP1alpha; PP1c 96A; PP1c; PP1; Pp1-96A; Pp1alpha-96A; pp1alpha-96A; pp1alpha96A", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase alpha-1 isoform; 3.1.3.16", "protein_names_refseq": "CG6593-PB; Pp1alpha-96A-PB; protein phosphatase 1alpha at 96A, isoform B; protein phosphatase 1alpha at 96A", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG6593); (R-DME-2500257); (R-DME-538898); (R-DME-9770562)", "pathway_count": 4, "publication_count": 15, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17007873;17569856;17569867;17575052;18327897;2176604;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5U0Y2;Q9VC69", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:1902494 catalytic complex", "go_biological_process": "GO:0005981 regulation of glycogen catabolic process;GO:0050829 defense response to Gram-negative bacterium;GO:0030514 negative regulation of BMP signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P48461-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z7K9-1", "uniprot_id": [ { "id": "PAN2_DROME", "url": "https://www.uniprot.org/uniprot/A1Z7K9", "type": "external" } ], "mass": 138968.0, "length": 1241, "protein_name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "gene_name": "PAN2", "organism": "Fruit fly", "refseq_name": "Poly(A)-binding protein-dependent poly(A) ribonuclease 2, isoform A", "refseq_ac": [ { "id": "NP_610427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610427", "type": "external" } ], "gene_names_uniprotkb": "PAN2; A1Z7K9; CG8232; Dmel\\CG8232; Dmel_CG8232; Pan2; pan2", "gene_names_refseq": "A1Z7K9; CG8232; Dmel\\CG8232; PAN2; Pan2; pan2", "protein_names_uniprotkb": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2; 3.1.13.4; PAB1P-dependent poly(A)-specific ribonuclease; PAN deadenylation complex subunit 2; Poly(A)-nuclease deadenylation complex subunit 2", "protein_names_refseq": "CG8232-PA; PAN2 ortholog; PAN2-PA; Poly(A)-binding protein-dependent poly(A) ribonuclease 2, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8232); (R-DME-429947)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;23932717;24880343;25589440;26109356;26109357;31114929", "class_list": "", "function": "Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.13.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.4", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" } ], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0031251 PAN complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A1Z7K9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P11612-1", "uniprot_id": [ { "id": "PPY_DROME", "url": "https://www.uniprot.org/uniprot/P11612", "type": "external" } ], "mass": 35980.0, "length": 314, "protein_name": "Serine/threonine-protein phosphatase PP-Y", "gene_name": "PpY-55A", "organism": "Fruit fly", "refseq_name": "protein phosphatase Y at 55A, isoform B", "refseq_ac": [ { "id": "NP_001286554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286554", "type": "external" } ], "gene_names_uniprotkb": "PpY-55A; CG10930; D19; DmPpY-55A; Dmel\\CG10930; Dmel_CG10930; PPY 55A; PPY; PpD19", "gene_names_refseq": "CG10930; D19; DmPpY-55A; Dmel\\CG10930; PPY 55A; PPY; PpD19; PpY-55A", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP-Y; 3.1.3.16", "protein_names_refseq": "CG10930-PB; PpY-55A-PB; protein phosphatase D19; protein phosphatase Y at 55A, isoform B; protein phosphatase from PCR fragment D19; protein phosphatase-Y", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10930); (R-DME-9770562)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1321058;16110336;17569856;17569867;2166691;2541022;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q26247;Q9V8A0", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P11612-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08841-1", "uniprot_id": [ { "id": "TBB3_DROME", "url": "https://www.uniprot.org/uniprot/P08841", "type": "external" } ], "mass": 50849.0, "length": 454, "protein_name": "Tubulin beta-3 chain", "gene_name": "betaTub60D", "organism": "Fruit fly", "refseq_name": "beta-Tubulin at 60D, isoform A", "refseq_ac": [ { "id": "NP_523842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523842", "type": "external" } ], "gene_names_uniprotkb": "betaTub60D; 143391_i_at; 3t; B3t; BETA 60D; CG3401; D.m.BETA-60D; DTB3; Dmbeta3; Dmel\\CG3401; Dmel_CG3401; Pin; Tac; Tub2E; Tub60D; TubB60C; Tub; T; beta-Tub60D; beta-Tub6D; beta-tub; beta3 TU; beta3-Tub; beta3-tubulin; beta3TUB; beta3Tub60D; beta3Tub; beta3tub; beta3t; beta3; beta60C; betaTub3; betaTub60C; betaTub; beta[[3]] tubulin; beta[[3]]-Tub; beta[[3]]-tubulin; betatub60D; betatubulin; p50; p53; tubulin", "gene_names_refseq": "143391_i_at; 3t; B3t; BETA 60D; CG3401; D.m.BETA-60D; DTB3; Dmbeta3; Dmel\\CG3401; Pin; Tac; Tub2E; Tub60D; Tub; T; beta-Tub60D; beta-Tub6D; beta-tub; beta3 TU; beta3-Tub; beta3-tubulin; beta3TUB; beta3Tub60D; beta3Tub; beta3tub; beta3t; beta3; beta60C; betaTub3; betaTub60C; betaTub60D; betaTub; beta[[3]] tubulin; beta[[3]]-Tub; beta[[3]]-tubulin; betatub60D; betatubulin; p50/tubulin; p50; p53/tubulin; p53; tubulin", "protein_names_uniprotkb": "Tubulin beta-3 chain; Beta-3-tubulin", "protein_names_refseq": "60C beta tubulin; B3-tubulin; CG3401-PA; Pin; b-3 tubulin; b3 tubulin; beta 3 tubulin; beta tubulin; beta-3 tubulin; beta-3-tubulin; beta-3tubulin; beta-Tubulin at 60A; beta-Tubulin at 60D, isoform A; beta-tubulin 60D; beta-tubulin at 60D; beta-tubulin60D; beta3 tubulin; beta3-tubulin; beta3tubulin; betaTub60D-PA; betatubulin; tack; tubulin b-3", "tax_id": 7227, "disease": "cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome (Disease Ontology:DOID:0050997); ptosis (Disease Ontology:DOID:0060260); congenital fibrosis of the extraocular muscles (Disease Ontology:DOID:0080143); congenital fibrosis of the extraocular muscles 3A (Disease Ontology:DOID:0081017); complex cortical dysplasia with other brain malformations 7 (Disease Ontology:DOID:0090132); complex cortical dysplasia with other brain malformations 1 (Disease Ontology:DOID:0090137); tubulinopathy (Disease Ontology:DOID:0112227); facial paralysis (Disease Ontology:DOID:13934)", "pathway": " (dme:Dmel_CG3401); (R-DME-3371497); (R-DME-6798695); (R-DME-6807878); (R-DME-6811436)", "pathway_count": 5, "publication_count": 16, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;1363225;15952742;16110336;17569856;17569867;25589440;26109356;26109357;3037352;8375576;8485515", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6I8M0;Q6I8M1;Q9W184", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007409 axonogenesis;GO:0000226 microtubule cytoskeleton organization;GO:0009416 response to light stimulus;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P08841-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41046-1", "uniprot_id": [ { "id": "CORTO_DROME", "url": "https://www.uniprot.org/uniprot/P41046", "type": "external" } ], "mass": 58771.0, "length": 550, "protein_name": "Centrosomal and chromosomal factor", "gene_name": "corto", "organism": "Fruit fly", "refseq_name": "corto, isoform B", "refseq_ac": [ { "id": "NP_001246921", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246921", "type": "external" } ], "gene_names_uniprotkb": "corto; 7128; CG2530; CP-1; Ccf; Corto; Dmel\\CG2530; Dmel_CG2530; anon-WO02059370.59; ccf; l(3)07128; l(3)neo31; l(3)neo32", "gene_names_refseq": "7128; CG2530; CP-1; Ccf; Corto; Dmel\\CG2530; anon-WO02059370.59; ccf; corto; l(3)07128; l(3)neo31; l(3)neo32", "protein_names_uniprotkb": "Centrosomal and chromosomal factor; CCF; Chromocentrosomin", "protein_names_refseq": "CG2530-PB; centrosomal and chromosomal factor; corto, isoform B; corto-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2530)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;12771214;16110336;17569856;17569867;18286205;18667003;25589440;26109356;26109357;9463384", "class_list": "", "function": "Essential protein required for proper condensation of mitotic chromosomes and progression through mitosis (PubMed:9463384). Binds to specific polytene chromosome sites, many of which are shared with the posterior sex combs (Psc) protein (PubMed:9463384). Involved in maintaining Abd-B repression outside its normal expression domain (PubMed:18286205, PubMed:18667003)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24271;Q494K5;Q961I6;Q9VN76", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0035098 ESC/E(Z) complex;GO:0035102 PRC1 complex", "go_biological_process": "GO:0060429 epithelium development;GO:0006351 DNA-templated transcription;GO:0051301 cell division;GO:0007076 mitotic chromosome condensation;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P41046-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O44342-1", "uniprot_id": [ { "id": "WBL_DROME", "url": "https://www.uniprot.org/uniprot/O44342", "type": "external" } ], "mass": 29444.0, "length": 257, "protein_name": "Protein windbeutel", "gene_name": "wbl", "organism": "Fruit fly", "refseq_name": "windbeutel, isoform B", "refseq_ac": [ { "id": "NP_001286609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286609", "type": "external" } ], "gene_names_uniprotkb": "wbl; CG7225; Dmel\\CG7225; Dmel_CG7225; Wbl; Windb; Wind; wbt; wind", "gene_names_refseq": "CG7225; Dmel\\CG7225; Wbl; Windb; Wind; wbl; wbt; wind", "protein_names_uniprotkb": "Protein windbeutel; Erp29 homolog", "protein_names_refseq": "CG7225-PB; wbl-PB; windbeutel, isoform B; windbeutel", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7225)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;11076773;12537568;12537572;12537573;12537574;12941941;15252019;16110336;17569856;17569867;25589440;26109356;26109357;9420336;9568717", "class_list": "", "function": "Probable chaperone protein involved in dorsoventral axis patterning in early embryos (PubMed:9568717). Probably acts by folding and targeting pipe (pip) into the Golgi (PubMed:11076773)., [UniProtKB, PubMed, PubMed]; Probable chaperone protein involved in dorsoventral axis patterning in early embryos. Probably acts by folding and targeting pipe (pip) into the Golgi., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 34, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V3T7", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0012505 endomembrane system", "go_biological_process": "GO:0009792 embryo development ending in birth or egg hatching;GO:0040014 regulation of multicellular organism growth;GO:0009306 protein secretion;GO:0009950 dorsal/ventral axis specification;GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "O44342-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46222-1", "uniprot_id": [ { "id": "RL11_DROME", "url": "https://www.uniprot.org/uniprot/P46222", "type": "external" } ], "mass": 21112.0, "length": 184, "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "RpL11", "organism": "Fruit fly", "refseq_name": "ribosomal protein L11, isoform B", "refseq_ac": [ { "id": "NP_001286614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286614", "type": "external" } ], "gene_names_uniprotkb": "RpL11; BcDNA:LD17235; CG7726; DL11; Dmel\\CG7726; Dmel_CG7726; EST A; L11; L5; RPL11A; RPL11; Rp L11; chr2R:14957112..14957299; l(2)k16914", "gene_names_refseq": "BcDNA:LD17235; CG7726; DL11; Dmel\\CG7726; EST A; L11; L5; RPL11; Rp L11; RpL11; chr2R:14957112..14957299; l(2)k16914", "protein_names_uniprotkb": "Large ribosomal subunit protein uL5; 60S ribosomal protein L11", "protein_names_refseq": "60S ribosomal protein L11; CG7726-PB; RpL11-PB; ribosomal protein DL11; ribosomal protein L11, isoform B", "tax_id": 7227, "disease": "Diamond-Blackfan anemia 7 (Disease Ontology:DOID:0111878); Diamond-Blackfan anemia (Disease Ontology:DOID:1339); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603)", "pathway": " (dme:Dmel_CG7726); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 15, "publication_id_list": "10731132;12368261;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;7893752", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V8U9", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit;GO:0005840 ribosome", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P46222-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P11956-1", "uniprot_id": [ { "id": "MT2_DROME", "url": "https://www.uniprot.org/uniprot/P11956", "type": "external" } ], "mass": 4525.0, "length": 43, "protein_name": "Metallothionein-2", "gene_name": "MtnB", "organism": "Fruit fly", "refseq_name": "metallothionein B, isoform B", "refseq_ac": [ { "id": "NP_001287425", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287425", "type": "external" } ], "gene_names_uniprotkb": "MtnB; CG4312; Dmel\\CG4312; Dmel_CG4312; DrosMto; MTNB; MTN; MTO; MT; MtnA; Mto; mtnB; mtnb", "gene_names_refseq": "CG4312; Dmel\\CG4312; DrosMto; MTNB; MTN; MTO; MT; MtnA; MtnB; Mto; mtnB; mtnb", "protein_names_uniprotkb": "Metallothionein-2; MT-2; Metallothionein B", "protein_names_refseq": "CG4312-PB; MtnB-PB; metallothionein B, isoform B; metallothionein B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4312)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;1976815;25589440;26109356;26109357;3106973", "class_list": "", "function": "This protein binds cations of several transition elements. Thought to be involved in metal ion homeostasis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1ECC1;Q9VDM2", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005507 copper ion binding", "go_cellular_component": "", "go_biological_process": "GO:0010038 response to metal ion;GO:0140961 cellular detoxification of metal ion", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P11956-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25931-1", "uniprot_id": [ { "id": "RYAR_DROME", "url": "https://www.uniprot.org/uniprot/P25931", "type": "external" } ], "mass": 53524.0, "length": 464, "protein_name": "RYamide receptor", "gene_name": "RYa-R", "organism": "Fruit fly", "refseq_name": "RYamide receptor, isoform A", "refseq_ac": [ { "id": "NP_524525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524525", "type": "external" } ], "gene_names_uniprotkb": "RYa-R; 107368; ATR; CG5811; Dm RYa-R; Dmel\\CG5811; Dmel_CG5811; NepYR; NepYr; PR4; anon-WO0131005.13; anon-WO0131005.15; dNepYr", "gene_names_refseq": "ATR; CG5811/107368; CG5811; Dm RYa-R; Dmel\\CG5811; NepYR; NepYr; PR4; RYa-R; anon-WO0131005.13; anon-WO0131005.15; dNepYr", "protein_names_uniprotkb": "RYamide receptor; NPY-R; Neuropeptide Y-like receptor", "protein_names_refseq": "CG5811-PA; RYa-R-PA; RYamide receptor, isoform A; neuropeptide Y receptor-like; neuropeptide Y-like receptor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5811)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;1370455;16110336;17569856;17569867;21704020;21843505;25589440;26109356;26109357", "class_list": "", "function": "Receptor for the neuropeptides RYamide-1 and RYamide-2 (PubMed:21704020, PubMed:21843505). The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system (PubMed:21704020, PubMed:21843505). RYamide signaling may suppress feeding behavior (PubMed:21704020)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWE5;Q9VB87", "ec_number_list": [], "go_molecular_function": "GO:0008188 neuropeptide receptor activity;GO:0004983 neuropeptide Y receptor activity;GO:0001653 peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P25931-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O76206-1", "uniprot_id": [ { "id": "RIFK_DROME", "url": "https://www.uniprot.org/uniprot/O76206", "type": "external" } ], "mass": 16986.0, "length": 153, "protein_name": "Putative riboflavin kinase", "gene_name": "Rfk", "organism": "Fruit fly", "refseq_name": "riboflavin kinase, isoform B", "refseq_ac": [ { "id": "NP_001287218", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287218", "type": "external" } ], "gene_names_uniprotkb": "Rfk; CG2846; C; Dmel\\CG2846; Dmel_CG2846; anon-84Ea", "gene_names_refseq": "CG2846; C; Dmel\\CG2846; Rfk; anon-84Ea", "protein_names_uniprotkb": "Putative riboflavin kinase; 2.7.1.26; ATP:riboflavin 5'-phosphotransferase; Flavokinase", "protein_names_refseq": "CG2846-PB; Rfk-PB; riboflavin kinase, isoform B; transcript C", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG2846); (R-DME-196843)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9601978", "class_list": "", "function": "Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B6IDS5;Q95S97", "ec_number_list": [ { "id": "2.7.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.26", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008531 riboflavin kinase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0009231 riboflavin biosynthetic process;GO:0009398 FMN biosynthetic process;GO:0006771 riboflavin metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "O76206-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08879-1", "uniprot_id": [ { "id": "NDKA_DROME", "url": "https://www.uniprot.org/uniprot/P08879", "type": "external" } ], "mass": 17170.0, "length": 153, "protein_name": "Nucleoside diphosphate kinase", "gene_name": "awd", "organism": "Fruit fly", "refseq_name": "abnormal wing discs, isoform E", "refseq_ac": [ { "id": "NP_001287624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287624", "type": "external" } ], "gene_names_uniprotkb": "awd; 08; AWD; Awd; BcDNA:GM19775; BcDNA:RH27794; CG2210; Dmel\\CG2210; Dmel_CG2210; K-pn; Kpn; NDKB; NDPK; Nm23; anon-EST:Liang-2.27; anon-EST:Liang-2.28; anon-WO0172774.80; anon-WO0172774.82; awd; clone 2.27; clone 2.28; e(shi)A; eshiA; l(3)L8700; l(3)j2A4", "gene_names_refseq": "1084/08; AWD; Awd; BcDNA:GM19775; BcDNA:RH27794; CG2210; Dmel\\CG2210; K-pn; Kpn; NDKB; NDPK; Nm23/awd; Nm23; anon-EST:Liang-2.27; anon-EST:Liang-2.28; anon-WO0172774.80; anon-WO0172774.82; awd; clone 2.27; clone 2.28; e(shi)A; eshiA; l(3)L8700; l(3)j2A4", "protein_names_uniprotkb": "Nucleoside diphosphate kinase; 2.7.4.6; Abnormal wing disks protein; Killer of prune protein; NDK; NDP kinase", "protein_names_refseq": "CG2210-PE; Killer-of-prune; NDP kinase; abnormal wing discs, isoform E; abnormal wing disc; abnormal wings disc; awd-PE; killer of prune; nucleoside diphosphate kinase", "tax_id": 7227, "disease": "prostate carcinoma (Disease Ontology:DOID:10286); urinary bladder cancer (Disease Ontology:DOID:11054); prostatic hypertrophy (Disease Ontology:DOID:11132); breast cancer (Disease Ontology:DOID:1612); squamous cell carcinoma (Disease Ontology:DOID:1749); ovary epithelial cancer (Disease Ontology:DOID:2152); arteriosclerosis (Disease Ontology:DOID:2349); ovarian cancer (Disease Ontology:DOID:2394); teratoma (Disease Ontology:DOID:3307); breast carcinoma (Disease Ontology:DOID:3459); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); ovarian carcinoma (Disease Ontology:DOID:4001); renal cell carcinoma (Disease Ontology:DOID:4450); congestive heart failure (Disease Ontology:DOID:6000); neuroblastoma (Disease Ontology:DOID:769)", "pathway": " (dme:Dmel_CG2210); (R-DME-499943); (R-DME-6798695); (R-DME-9748787); (R-DME-9755088)", "pathway_count": 5, "publication_count": 21, "publication_id_list": "10731132;12099695;12537568;12537569;12537572;12537573;12537574;1320004;16110336;17569856;17569867;18327897;2175255;25589440;26109356;26109357;2849580;7559441;7669763;8081741;8500545", "class_list": "", "function": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V9U5", "ec_number_list": [ { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" }, { "id": "5.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.7", "type": "external" }, { "id": "5.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.-", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "5.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.5", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0008017 microtubule binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0005880 nuclear microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0009117 nucleotide metabolic process;GO:0034332 adherens junction organization;GO:0007017 microtubule-based process;GO:0006183 GTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P08879-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08266-1", "uniprot_id": [ { "id": "RPB2_DROME", "url": "https://www.uniprot.org/uniprot/P08266", "type": "external" } ], "mass": 134043.0, "length": 1176, "protein_name": "DNA-directed RNA polymerase II subunit RPB2", "gene_name": "Polr2B", "organism": "Fruit fly", "refseq_name": "RNA polymerase II subunit B, isoform B", "refseq_ac": [ { "id": "NP_001287323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287323", "type": "external" } ], "gene_names_uniprotkb": "Polr2B; CG3180; DmRP140; Dmel\\CG3180; Dmel_CG3180; H5; II; Pol IIc; Pol II; PolIIc; PolII; RNA Pol II 140; RNA Pol IIc; RNA Pol II; RNA pol II; RNA polII; RNAP II; RNAP; RNApolII; RP140; RPB2_DROME; RPB2; RPII140; RpII140[wimp]; RpII140; RpIl140; Rpb2; Rpll140; l(3)RplII140; pol II; polII; wimp", "gene_names_refseq": "CG3180; DmRP140; Dmel\\CG3180; H5; II; Pol IIc; Pol II; PolIIc; PolII; Polr2B; RNA Pol II 140; RNA Pol IIc; RNA Pol II; RNA pol II; RNA polII; RNAP II; RNAP; RNApolII; RP140; RPB2_DROME; RPB2; RPII140; RpII140[wimp]; RpII140; RpIl140; Rpb2; Rpll140; l(3)RplII140; pol II; polII; rpII140/wimp; wimp", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB2; 2.7.7.6; DNA-directed RNA polymerase II 140 kDa polypeptide; RNA polymerase II subunit 2; RNA polymerase II subunit B2; RNA polymerase II subunit B", "protein_names_refseq": "150kDa polypeptide; CG3180-PB; Pol II; Polr2B-PB; RNA pol II second largest subunit; RNA polymerase II 140 kD subunit; RNA polymerase II 140kD subunit; RNA polymerase II second largest subunit; RNA polymerase II subunit B, isoform B; RNA polymerase IIc; RNA polymerase subunit IIc; RNA polymeraseII-140 kd subunit; Rpb2; subunit IIc of RNA Pol II; wimp", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3180); (R-DME-112382); (R-DME-113418); (R-DME-5578749); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-6807505); (R-DME-72086); (R-DME-72163); (R-DME-72165); (R-DME-72203); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075); (R-DME-9018519); (R-DME-9770562)", "pathway_count": 22, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;1905256;25589440;26109356;26109357;3116266", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q04155;Q95027;Q9VFM7", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "2.1.1.348", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.348", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.1.1.56", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.56", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0032549 ribonucleoside binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005665 RNA polymerase II, core complex;GO:0005654 nucleoplasm;GO:0000428 DNA-directed RNA polymerase complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006354 DNA-templated transcription elongation;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P08266-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0B7P9G0-1", "uniprot_id": [ { "id": "UEX_DROME", "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0", "type": "external" } ], "mass": 93283.0, "length": 834, "protein_name": "Unextended protein", "gene_name": "uex", "organism": "Fruit fly", "refseq_name": "unextended, isoform F", "refseq_ac": [ { "id": "NP_001104390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390", "type": "external" } ], "gene_names_uniprotkb": "uex; 41Ad; CG42595; GroupIII; l(2)41Ad", "gene_names_refseq": "41Ad; CG40084; CG42595; CR41594; Dmel\\CG42595; EMS45-73; GroupIII; IR3; l(2)41Ad; l(2)EMS34-7; l(2)IR3; l(2R)A'; l(2R)EMS45-73; l(2Rh)IR3; uex", "protein_names_uniprotkb": "Unextended protein; Putative metal transporter uex", "protein_names_refseq": "CG42595-PF; lethal (2) IR3; uex-PF; unextended, isoform F", "tax_id": 7227, "disease": "renal hypomagnesemia 6 (Disease Ontology:DOID:0060884); Jalili syndrome (Disease Ontology:DOID:0111404); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG42595)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;31404830", "class_list": "", "function": "Probable metal transporter (By similarity). Acts downstream of PRL-1 and protects the nervous system against olfactory carbon dioxide stimulation (PubMed:31404830)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:1903830 magnesium ion transmembrane transport;GO:0007616 long-term memory;GO:0010960 magnesium ion homeostasis;GO:0006873 intracellular monoatomic ion homeostasis;GO:0140115 export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0B7P9G0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P07665-1", "uniprot_id": [ { "id": "SRYB_DROME", "url": "https://www.uniprot.org/uniprot/P07665", "type": "external" } ], "mass": 41709.0, "length": 356, "protein_name": "Serendipity locus protein beta", "gene_name": "Sry-beta", "organism": "Fruit fly", "refseq_name": "serendipity beta, isoform B", "refseq_ac": [ { "id": "NP_001303451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303451", "type": "external" } ], "gene_names_uniprotkb": "Sry-beta; CG7938; Dmel\\CG7938; Dmel_CG7938; SrY-beta; Sry-b; Srybeta; ser; sry beta; sry-beta; sry-b; srybeta; sryb; sry", "gene_names_refseq": "CG7938; Dmel\\CG7938; SrY-beta; Sry-beta; Srybeta; ser; sry beta; sry-beta; sry-b; srybeta; sryb; sry", "protein_names_uniprotkb": "Serendipity locus protein beta", "protein_names_refseq": "CG7938-PB; Sry-beta-PB; serendipity beta, isoform B; serendipity beta", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7938)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;1732741;17569856;17569867;1868833;2081456;25589440;26109356;26109357;3935797", "class_list": "", "function": "Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VAB5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005705 polytene chromosome interband", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P07665-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8DYY6-1", "uniprot_id": [ { "id": "SCHI1_DROME", "url": "https://www.uniprot.org/uniprot/A8DYY6", "type": "external" } ], "mass": 70514.0, "length": 616, "protein_name": "Schwannomin-interacting protein 1 homolog", "gene_name": "Schip1", "organism": "Fruit fly", "refseq_name": "schwannomin interacting protein 1, isoform B", "refseq_ac": [ { "id": "NP_001097139", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097139", "type": "external" } ], "gene_names_uniprotkb": "Schip1; CG5375; Dmel\\CG5375; Dmel_CG5375", "gene_names_refseq": "CG5375; Dmel\\CG5375; Schip1", "protein_names_uniprotkb": "Schwannomin-interacting protein 1 homolog", "protein_names_refseq": "CG5375-PB; Schip1 ortholog; Schip1-PB; schwannomin interacting protein 1, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5375)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;26954546", "class_list": "", "function": "Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (hpo), in complex with its regulatory protein Salvador (sav), phosphorylates and activates Warts (wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (yki) oncoprotein. Schip1 promotes kinase activity of Tao and enhances phosphorylation of hpo by Tao., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0030054 cell junction;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0071902 positive regulation of protein serine/threonine kinase activity;GO:0035332 positive regulation of hippo signaling;GO:0045926 negative regulation of growth", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A8DYY6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40421-1", "uniprot_id": [ { "id": "RDGC_DROME", "url": "https://www.uniprot.org/uniprot/P40421", "type": "external" } ], "mass": 75511.0, "length": 661, "protein_name": "Serine/threonine-protein phosphatase rdgC", "gene_name": "rdgC", "organism": "Fruit fly", "refseq_name": "retinal degeneration C, isoform F", "refseq_ac": [ { "id": "NP_536738", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_536738", "type": "external" } ], "gene_names_uniprotkb": "rdgC; CG13814; CG44746; CG6571; Dmel\\CG44746; Dmel_CG44746; DmrdgC-77B; PP5; RDGC; RdgC 77B; RdgC", "gene_names_refseq": "CG13814; CG44746; CG6571; Dmel\\CG44746; DmrdgC-77B; RDGC/PP5; RDGC; RdgC 77B; RdgC; rdgC", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase rdgC; 3.1.3.16; Retinal degeneration C protein", "protein_names_refseq": "CG44746-PF; rdgC-PF; retinal degeneration C, isoform F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44746)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;1316807;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Phosphatase required to prevent light-induced retinal degeneration., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V255;Q5U1D3;Q9VWA4", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0005516 calmodulin binding;GO:0030145 manganese ion binding;GO:0005509 calcium ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0050906 detection of stimulus involved in sensory perception;GO:0019722 calcium-mediated signaling;GO:0007601 visual perception;GO:0007602 phototransduction;GO:0016059 negative regulation of opsin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40421-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z6J5-1", "uniprot_id": [ { "id": "TBCE_DROME", "url": "https://www.uniprot.org/uniprot/A1Z6J5", "type": "external" } ], "mass": 59424.0, "length": 523, "protein_name": "Tubulin-specific chaperone E", "gene_name": "Tbce", "organism": "Fruit fly", "refseq_name": "Tubulin-binding cofactor E, isoform C", "refseq_ac": [ { "id": "NP_610197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610197", "type": "external" } ], "gene_names_uniprotkb": "Tbce; CG7861", "gene_names_refseq": "CG7861; Dmel\\CG7861; TBCE; Tbce; dTBCE; tbce", "protein_names_uniprotkb": "Tubulin-specific chaperone E; Tubulin-folding cofactor E", "protein_names_refseq": "CG7861-PC; Tbce-PC; Tubulin-binding cofactor E, isoform C; tubulin-specific chaperone E", "tax_id": 7227, "disease": "hypoparathyroidism-retardation-dysmorphism syndrome (Disease Ontology:DOID:0060348); Kenny-Caffey syndrome type 1 (Disease Ontology:DOID:0080722); hypoparathyroidism (Disease Ontology:DOID:11199)", "pathway": " (dme:Dmel_CG7861)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;19297412", "class_list": "", "function": "Tubulin-folding protein which is required for the development of the neuronal microtubule network. Essential for the development and function of neuromuscular synapses. Likely to promote microtubule formation by acting in the negative regulation of the microtubule-severing protein spas., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1Z6J4;Q8MT85", "ec_number_list": [], "go_molecular_function": "GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045202 synapse", "go_biological_process": "GO:0046785 microtubule polymerization;GO:0007274 neuromuscular synaptic transmission;GO:0007399 nervous system development;GO:0000226 microtubule cytoskeleton organization;GO:0007021 tubulin complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A1Z6J5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z6M0-1", "uniprot_id": [ { "id": "A1Z6M0_DROME", "url": "https://www.uniprot.org/uniprot/A1Z6M0", "type": "external" } ], "mass": 183029.0, "length": 1688, "protein_name": "Brahma associated protein 170kD", "gene_name": "Bap170", "organism": "Fruit fly", "refseq_name": "brahma associated protein 170kD", "refseq_ac": [ { "id": "NP_610216", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610216", "type": "external" } ], "gene_names_uniprotkb": "Bap170; BAP 170; BAP170; BcDNA:GH12174; CG3274; Dmel\\CG3274; Dmel_CG3274; bap170; hfl", "gene_names_refseq": "BAP 170; BAP170; Bap170; BcDNA:GH12174; CG3274; Dmel\\CG3274; bap170; hfl", "protein_names_uniprotkb": "Brahma associated protein 170kD", "protein_names_refseq": "Bap170-PA; CG3274-PA; brahma associated protein 170kD; half-life", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Coffin-Siris syndrome 6 (Disease Ontology:DOID:0080297); alcohol use disorder (Disease Ontology:DOID:1574); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG3274)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0035060 brahma complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0050821 protein stabilization;GO:0008586 imaginal disc-derived wing vein morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A1Z6M0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z6P3-1", "uniprot_id": [ { "id": "A1Z6P3_DROME", "url": "https://www.uniprot.org/uniprot/A1Z6P3", "type": "external" } ], "mass": 33293.0, "length": 297, "protein_name": "Eb1, isoform F", "gene_name": "Eb1", "organism": "Fruit fly", "refseq_name": "Eb1, isoform F", "refseq_ac": [ { "id": "NP_724495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724495", "type": "external" } ], "gene_names_uniprotkb": "Eb1; BcDNA.LD08743; BcDNA:LD08743; CG3265; Dm EB1; DmEB1; Dmel\\CG3265; Dmel_CG3265; EB-1; EB1; S(DmcycE[JP])2.5; anon-EST:Liang-2.33; anon-EST:Liang-2.52; clone 2.33; clone 2.52; dEB-1; dEB1; dEb1; dmEB1; eb1; l(2)04524; l(2)4524", "gene_names_refseq": "BcDNA.LD08743; BcDNA:LD08743; CG3265; Dm EB1; DmEB1; Dmel\\CG3265; EB-1; EB1; Eb1; S(DmcycE[JP])2.5; anon-EST:Liang-2.33; anon-EST:Liang-2.52; clone 2.33; clone 2.52; dEB-1; dEB1; dEb1; dmEB1; eb1; l(2)04524; l(2)4524", "protein_names_uniprotkb": "Eb1, isoform F", "protein_names_refseq": "+TIP End-Binding 1; CG3265-PF; Eb1, isoform F; Eb1-PF; MT-plus-end-binding protein; microtubule plus-tip protein EB1", "tax_id": 7227, "disease": "congenital symmetric circumferential skin creases 2 (Disease Ontology:DOID:0112243)", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D0Z742", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0017022 myosin binding;GO:0051010 microtubule plus-end binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0051233 spindle midzone;GO:0005815 microtubule organizing center;GO:0005875 microtubule associated complex", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0007059 chromosome segregation;GO:0007626 locomotory behavior;GO:0051301 cell division;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z6P3-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z7A5-1", "uniprot_id": [ { "id": "A1Z7A5_DROME", "url": "https://www.uniprot.org/uniprot/A1Z7A5", "type": "external" } ], "mass": 18223.0, "length": 159, "protein_name": "Under-developed", "gene_name": "udd", "organism": "Fruit fly", "refseq_name": "under-developed", "refseq_ac": [ { "id": "NP_610353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610353", "type": "external" } ], "gene_names_uniprotkb": "udd; CG18316; Dmel\\CG18316; Dmel_CG18316; Udd", "gene_names_refseq": "CG18316; Dmel\\CG18316; Udd; udd", "protein_names_uniprotkb": "Under-developed", "protein_names_refseq": "CG18316-PA; udd-PA; under developed; under-developed", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18316)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005668 RNA polymerase transcription factor SL1 complex;GO:0005730 nucleolus", "go_biological_process": "GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z7A5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z7U3-1", "uniprot_id": [ { "id": "OST4_DROME", "url": "https://www.uniprot.org/uniprot/A1Z7U3", "type": "external" } ], "mass": 4368.0, "length": 40, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Ost4", "gene_name": "Ost4", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001027396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027396", "type": "external" } ], "gene_names_uniprotkb": "Ost4; CG33774", "gene_names_refseq": "BcDNA:GM20929; CG33774; Dm_2R:21419; Dmel\\CG33774", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Ost4; Oligosaccharyltransferase complex subunit 4", "protein_names_refseq": "CG33774-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33774)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IH26", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0160226 oligosaccharyltransferase complex A;GO:0160227 oligosaccharyltransferase complex B", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0180058 protein co-translational transfer of dolichol-linked oligosaccharide;GO:0180057 protein post-translational transfer of dolichol-linked oligosaccharide", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A1Z7U3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z877-1", "uniprot_id": [ { "id": "NDG_DROME", "url": "https://www.uniprot.org/uniprot/A1Z877", "type": "external" } ], "mass": 149081.0, "length": 1350, "protein_name": "Nidogen", "gene_name": "Ndg", "organism": "Fruit fly", "refseq_name": "nidogen, isoform A", "refseq_ac": [ { "id": "NP_610575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610575", "type": "external" } ], "gene_names_uniprotkb": "Ndg; CG12908", "gene_names_refseq": "BEST:CK00552; CG12908; CT32053; Dmel\\CG12908; Ndg; ndg", "protein_names_uniprotkb": "Nidogen; Entactin", "protein_names_refseq": "CG12908-PA; Ndg-PA; Nidogen-like; nidogen, isoform A; nidogen/entactin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12908)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;28604694;30260959;30567930", "class_list": "", "function": "Cell adhesion glycoprotein which is widely distributed in basement membranes (PubMed:30260959, PubMed:30567930). Involved in cell-extracellular matrix (ECM) interactions probably by connecting the laminin and collagen IV networks (PubMed:30260959, PubMed:30567930). Required for permeability and mechanical stability of basement membranes, and ECM dependent neural plasticity (PubMed:30567930). Not involved in assembly of the embryonic basement membrane (PubMed:30567930)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "A1Z876;B7FNR1", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0005604 basement membrane", "go_biological_process": "GO:0007160 cell-matrix adhesion;GO:0071711 basement membrane organization;GO:0110011 regulation of basement membrane organization;GO:2001197 basement membrane assembly involved in embryonic body morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A1Z877-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0100000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z8D0-1", "uniprot_id": [ { "id": "PWP1_DROME", "url": "https://www.uniprot.org/uniprot/A1Z8D0", "type": "external" } ], "mass": 51391.0, "length": 459, "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "nclb", "organism": "Fruit fly", "refseq_name": "no child left behind", "refseq_ac": [ { "id": "NP_610623", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610623", "type": "external" } ], "gene_names_uniprotkb": "nclb; CG6751; dpwp1", "gene_names_refseq": "CG6751; Dmel\\CG6751; Nclb; PWP1; dPWP1; nclb", "protein_names_uniprotkb": "Periodic tryptophan protein 1 homolog; PWP1; Protein no child left behind", "protein_names_refseq": "CG6751-PA; nclb-PA; no child left behind", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6751)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;21752937;29065309", "class_list": "", "function": "Chromatin-associated factor that regulates transcription (PubMed:21752937). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309). Regulates the localization to the nucleolus of Cdk7, a regulator of the Pol I-elongation factor TFIIH (PubMed:29065309). Acts as a regulator of cell proliferation and tissue growth as part of the TORC1 and Myc signaling pathway in response to nutrients (PubMed:29065309). Required in males for both germline stem cell (GSC) maintenance and early stages of germ cell differentiation of germ cell cysts (PubMed:21752937). Not required for female germline stem cell (GSC) maintenance, but necessary to regulate germ cell differentiation and egg chamber development (PubMed:21752937). In female somatic cells, required for follicle stem cell survival and maintenance (PubMed:21752937)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5X0K1;Q8SY06", "ec_number_list": [], "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:1990889 histone H4K20me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032869 cellular response to insulin stimulus;GO:0008584 male gonad development;GO:0007281 germ cell development;GO:0045945 positive regulation of transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A1Z8D0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z8K2-1", "uniprot_id": [ { "id": "A1Z8K2_DROME", "url": "https://www.uniprot.org/uniprot/A1Z8K2", "type": "external" } ], "mass": 62999.0, "length": 605, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13204", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_610678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610678", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG13204; 13204; CG13204; Dmel_CG13204", "gene_names_refseq": "13204; CG13204; Dmel\\CG13204", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13204-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13204)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z8K2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1Z9A8-1", "uniprot_id": [ { "id": "PTCD3_DROME", "url": "https://www.uniprot.org/uniprot/A1Z9A8", "type": "external" } ], "mass": 74207.0, "length": 652, "protein_name": "Small ribosomal subunit protein mS39", "gene_name": "Ptcd3", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_610854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610854", "type": "external" } ], "gene_names_uniprotkb": "Ptcd3; CG4679", "gene_names_refseq": "CG4679; Dmel\\CG4679; RE17985p", "protein_names_uniprotkb": "Small ribosomal subunit protein mS39; Pentatricopeptide repeat domain-containing protein 3 homolog, mitochondrial", "protein_names_refseq": "CG4679-PA; uncharacterized protein", "tax_id": 7227, "disease": "combined oxidative phosphorylation deficiency 51 (Disease Ontology:DOID:0112137)", "pathway": " (dme:Dmel_CG4679); (R-DME-5389840); (R-DME-5419276); (R-DME-9937383)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;38074476", "class_list": "", "function": "Mitochondrial protein that may have a role in mitochondrial translation (By similarity) (PubMed:38074476). Essential for larval development (PubMed:38074476)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MRC2;T2FGD8", "ec_number_list": [], "go_molecular_function": "GO:0043024 ribosomal small subunit binding;GO:0019843 rRNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A1Z9A8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZAB3-1", "uniprot_id": [ { "id": "A1ZAB3_DROME", "url": "https://www.uniprot.org/uniprot/A1ZAB3", "type": "external" } ], "mass": 160062.0, "length": 1433, "protein_name": "3.1.3.-; 3.1.3.48; Protein tyrosine phosphatase 52F", "gene_name": "Ptp52F", "organism": "Fruit fly", "refseq_name": "protein tyrosine phosphatase 52F", "refseq_ac": [ { "id": "NP_611093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611093", "type": "external" } ], "gene_names_uniprotkb": "Ptp52F; CG18243; CT18044; DPTP52F; Dmel\\CG18243; Dmel_CG18243; PTP52F; ptp52F", "gene_names_refseq": "CG18243; CT18044; DPTP52F; Dmel\\CG18243; PTP52F; Ptp52F; ptp52F", "protein_names_uniprotkb": "3.1.3.-; 3.1.3.48; Protein tyrosine phosphatase 52F", "protein_names_refseq": "CG18243-PB; Ptp52F-PB; protein tyrosine phosphatase 52F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18243); (R-DME-1433557); (R-DME-182971)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0005001 transmembrane receptor protein tyrosine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0007411 axon guidance;GO:0008045 motor neuron axon guidance;GO:0035075 response to ecdysone", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZAB3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A1ZB42-1", "uniprot_id": [ { "id": "MED9_DROME", "url": "https://www.uniprot.org/uniprot/A1ZB42", "type": "external" } ], "mass": 16808.0, "length": 144, "protein_name": "Mediator of RNA polymerase II transcription subunit 9", "gene_name": "MED9", "organism": "Fruit fly", "refseq_name": "mediator complex subunit 9", "refseq_ac": [ { "id": "NP_788400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788400", "type": "external" } ], "gene_names_uniprotkb": "MED9; CG5134", "gene_names_refseq": "BcDNA:LD07740; BcDNA:RH42446; CG30112; CG30113; CG42517; CG5134; Dmel\\CG42517; MED9; Med9; med9", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 9; Mediator complex subunit 9", "protein_names_refseq": "CG42517-PC; CPuORF of FBgn0260392; MED9-PC; mediator complex subunit 9", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42517)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1ZB41;Q8IGE5;Q8MR32", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A1ZB42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40320-1", "uniprot_id": [ { "id": "METK_DROME", "url": "https://www.uniprot.org/uniprot/P40320", "type": "external" } ], "mass": 44697.0, "length": 408, "protein_name": "S-adenosylmethionine synthase", "gene_name": "Sams", "organism": "Fruit fly", "refseq_name": "S-adenosylmethionine synthetase, isoform C", "refseq_ac": [ { "id": "NP_524923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524923", "type": "external" } ], "gene_names_uniprotkb": "Sams; CG2674; Dmel\\CG2674; Dmel_CG2674; M(2)21A-B; M(2)21AB; METK; SAM; Sam-S; SamS; Su(z)5; m(2)21ab; sams", "gene_names_refseq": "CG2674; Dmel\\CG2674; M(2)21A-B; M(2)21AB; METK; SAM; Sam-S; SamS; Sams; Su(z)5; m(2)21ab; sams", "protein_names_uniprotkb": "S-adenosylmethionine synthase; 2.5.1.6; AdoMet synthase; MAT; Methionine adenosyltransferase", "protein_names_refseq": "CG2674-PC; S-Adenosylmethionine synthetase; S-adenosylmethionine synthetase, isoform C; SAM synthase; Sam-S-PC; methionine adenosyl transferase; minute (2) 21AB", "tax_id": 7227, "disease": "hypermethioninemia (Disease Ontology:DOID:0050544); fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); lung cancer (Disease Ontology:DOID:1324); lipid metabolism disorder (Disease Ontology:DOID:3146); amino acid metabolic disorder (Disease Ontology:DOID:9252)", "pathway": " (dme:Dmel_CG2674); (R-DME-156581); (R-DME-1614635); (R-DME-2408508)", "pathway_count": 4, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8150093", "class_list": "", "function": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP., [UniProtKB, UniProtKB]; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8V3;Q9VPJ2;Q9VPJ3;Q9VPJ4;Q9VPJ5", "ec_number_list": [ { "id": "2.5.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004478 methionine adenosyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0006556 S-adenosylmethionine biosynthetic process;GO:0008340 determination of adult lifespan", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40320-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42519-1", "uniprot_id": [ { "id": "STAR_DROME", "url": "https://www.uniprot.org/uniprot/P42519", "type": "external" } ], "mass": 65818.0, "length": 597, "protein_name": "Protein Star", "gene_name": "S", "organism": "Fruit fly", "refseq_name": "star, isoform B", "refseq_ac": [ { "id": "NP_523450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523450", "type": "external" } ], "gene_names_uniprotkb": "S; CG4385; Dmel\\CG4385; Dmel_CG4385; E(Raf)2B; EC2-2; EK2-2; ES2-4; EY2-4; asteroid; fltr; l(2)05671; l(2)07056; l(2)21Eb; l(2)c00080; l(2)k09538; l(2)rK134; star; s", "gene_names_refseq": "CG4385; Dmel\\CG4385; E(Raf)2B; EC2-2; EK2-2; ES2-4; EY2-4; Star/asteroid; S; fltr; l(2)05671; l(2)07056; l(2)21Eb; l(2)c00080; l(2)k09538; l(2)rK134; star; s", "protein_names_uniprotkb": "Protein Star", "protein_names_refseq": "CG4385-PB; S-PB; enhancer of GMR-sina 2-4; floater; lethal (2) c00080; star, isoform B; star", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG4385)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;11672524;11790319;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7924981", "class_list": "", "function": "Involved in EGF receptor signaling. Has an early role in photoreceptor development. Interacts with the receptor torpedo in the eye., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPW0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum", "go_biological_process": "GO:0048149 behavioral response to ethanol;GO:0050714 positive regulation of protein secretion;GO:0007601 visual perception;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016197 endosomal transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P42519-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35415-1", "uniprot_id": [ { "id": "MYSP1_DROME", "url": "https://www.uniprot.org/uniprot/P35415", "type": "external" } ], "mass": 102338.0, "length": 879, "protein_name": "Paramyosin, long form", "gene_name": "Prm", "organism": "Fruit fly", "refseq_name": "paramyosin, isoform A", "refseq_ac": [ { "id": "NP_523982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523982", "type": "external" } ], "gene_names_uniprotkb": "Prm; 05; CG5939; Dmel\\CG5939; Dmel_CG5939; PM; Para; l(3)10631; l(3)S010605; mPM; pm; prm", "gene_names_refseq": "0106/05; CG5939; Dmel\\CG5939; PM/mPM; PM; Para; Prm; l(3)10631; l(3)S010605; mPM; pm; prm", "protein_names_uniprotkb": "Paramyosin, long form", "protein_names_refseq": "CG5939-PA; Prm-PA; lethal (3) S010605; paramyosin, isoform A; paramyosin/miniparamyosin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5939); (R-DME-3928662); (R-DME-416482); (R-DME-416572); (R-DME-4420097); (R-DME-5627117); (R-DME-8980692); (R-DME-9013407); (R-DME-9013422)", "pathway_count": 9, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1371577;16110336;1730773;17569856;17569867;18327897;1908014;25589440;26109356;26109357;40245499", "class_list": "", "function": "Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8T0Q3;Q9VSP6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0031430 M band;GO:0016459 myosin complex;GO:0005863 striated muscle myosin thick filament", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0031032 actomyosin structure organization;GO:0048598 embryonic morphogenesis;GO:0030866 cortical actin cytoskeleton organization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P35415-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48605-1", "uniprot_id": [ { "id": "TCPG_DROME", "url": "https://www.uniprot.org/uniprot/P48605", "type": "external" } ], "mass": 59395.0, "length": 544, "protein_name": "T-complex protein 1 subunit gamma", "gene_name": "CCT3", "organism": "Fruit fly", "refseq_name": "chaperonin containing TCP1 subunit 3, isoform C", "refseq_ac": [ { "id": "NP_001189236", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189236", "type": "external" } ], "gene_names_uniprotkb": "CCT3; CCTgamma; CG8977; Cct-gamma; Cct3; Cctgamma; Cctg; Dmel\\CG8977; Dmel_CG8977; TCP1-gamma; TCPG_DROME; Tcp-1-gamma; Tcp-1gamma; Tcp1-gamma; Y; cct-gamma; cct3; cctgamma; cctg; geneY; vine", "gene_names_refseq": "CCT3; CCTgamma; CG8977; Cct-gamma; Cct3; Cctgamma; Cctg; Dmel\\CG8977; TCP1-gamma; TCPG_DROME; Tcp-1-gamma; Tcp-1gamma; Tcp1-gamma; Y; cct-gamma; cct3; cctgamma; cctg; geneY; vine", "protein_names_uniprotkb": "T-complex protein 1 subunit gamma; CCT-gamma; Chaperonin containing TCP1 subunit 3; TCP-1-gamma", "protein_names_refseq": "CCT-gamma protein; CCT3-PC; CCTgamma-like; CG8977-PC; TCP-1 subunit 3gamma; cctgamma; chaperonin containing TCP1 subunit 3, isoform C; chaperonin-containing t-complex protein-1 gamma subunit like; predicted gene Y; vine", "tax_id": 7227, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (dme:Dmel_CG8977); (R-DME-390471); (R-DME-6814122)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7667301;8666276", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VER9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding;GO:0007430 terminal branching, open tracheal system;GO:0035149 lumen formation, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P48605-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8DYP0-1", "uniprot_id": [ { "id": "OBSCN_DROME", "url": "https://www.uniprot.org/uniprot/A8DYP0", "type": "external" } ], "mass": 475655.0, "length": 4218, "protein_name": "Protein Obscurin", "gene_name": "Obsc", "organism": "Fruit fly", "refseq_name": "obscurin, isoform D", "refseq_ac": [ { "id": "NP_001014545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014545", "type": "external" } ], "gene_names_uniprotkb": "Obsc; CG33519; Unc-89", "gene_names_refseq": "BEST:HL01080; CG18019; CG18020; CG18021; CG30171; CG30175; CG33519; CG3901; CT12925; CT40322; CT40326; Dmel\\CG33519; Obsc; UNC-89; Unc-89; dmObsc; obs; unc-89", "protein_names_uniprotkb": "Protein Obscurin; Inactive serine/threonine-protein kinase obscurin; Muscle M-line assembly protein Unc-89", "protein_names_refseq": "CG33519-PD; Obsc-PD; PROJECTIN-like; Unc-89; obscurin, isoform D; obscurin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33519)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;12537572;15185077;18515368;22467859;26251439;37121260;40245499", "class_list": "", "function": "Structural component of the muscle M line which is involved in assembly and organization of sarcomere (PubMed:22467859, PubMed:26251439). Required for the development and organization of indirect flight muscle sarcomeres by regulating the formation of M line and H zone and the correct assembly of thick and thin filaments in the sarcomere (PubMed:22467859, PubMed:26251439). Lacks serine/threonine-protein kinase activity (PubMed:37121260)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4LGC9;A0A0B4LGE3;A0A0B4LGI5;A0A0B4LHF2;Q1ZYJ8;Q59E65", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0005523 tropomyosin binding", "go_cellular_component": "GO:0031430 M band", "go_biological_process": "GO:0045214 sarcomere organization;GO:0036309 protein localization to M-band;GO:0007527 adult somatic muscle development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8DYP0-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8DYY5-1", "uniprot_id": [ { "id": "RPAP2_DROME", "url": "https://www.uniprot.org/uniprot/A8DYY5", "type": "external" } ], "mass": 16330.0, "length": 143, "protein_name": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog", "gene_name": "CG34183", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_001097134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097134", "type": "external" } ], "gene_names_uniprotkb": "CG34183", "gene_names_refseq": "CG34183; Dmel\\CG34183", "protein_names_uniprotkb": "Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog; 3.1.3.16; RNA polymerase II-associated protein 2", "protein_names_refseq": "CG34183-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34183)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1A6P2;A1A6T3;A1A6V6", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043175 RNA polymerase core enzyme binding;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A8DYY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P31368-1", "uniprot_id": [ { "id": "PDM1_DROME", "url": "https://www.uniprot.org/uniprot/P31368", "type": "external" } ], "mass": 65202.0, "length": 601, "protein_name": "Protein nubbin", "gene_name": "nub", "organism": "Fruit fly", "refseq_name": "nubbin, isoform E", "refseq_ac": [ { "id": "NP_001285876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285876", "type": "external" } ], "gene_names_uniprotkb": "nub; CG15488; CG15489; CG34395; CG6246; Dmel\\CG34395; Dmel_CG34395; NUB; Nb; Nubbin; Nub; OCT1; Oct-1; Oct1; PDM-1; PDM1; POU-19; POU33F1; Pdm-1; Pdm1; Pdm; TWN; dOct1; dPOU-19; dPOU19; nb; nubbin; pdm-1; pdm1; pdm; twn", "gene_names_refseq": "CG15488; CG15489; CG34395; CG6246; Dmel\\CG34395; NUB; Nb; Nubbin; Nub; Oct-1; Oct1; PDM-1; PDM1; POU33F1; Pdm-1; Pdm1/nubbin; Pdm1; Pdm; dOct1; dPOU-19/pdm-1; dPOU-19; dPOU19; nb; nub; pdm-1; pdm1; pdm; twn", "protein_names_uniprotkb": "Protein nubbin; PDM-1; POU domain protein 1; Protein twain; dOCT1; dPOU-19", "protein_names_refseq": "CG34395-PE; NUBBIN; POU domain 1; POU domain protein 1; Pdm1; nub-PE; nubbin, isoform E; twain", "tax_id": 7227, "disease": "immune system disease (Disease Ontology:DOID:2914)", "pathway": " (dme:Dmel_CG34395); (R-DME-6807505)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;1680380;1685891;17569856;17569867;1881906;25589440;26109356;26109357", "class_list": "", "function": "DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VK74", "ec_number_list": [], "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048813 dendrite morphogenesis;GO:0050767 regulation of neurogenesis;GO:2000177 regulation of neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P31368-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16621-1", "uniprot_id": [ { "id": "LAR_DROME", "url": "https://www.uniprot.org/uniprot/P16621", "type": "external" } ], "mass": 229056.0, "length": 2029, "protein_name": "Tyrosine-protein phosphatase Lar", "gene_name": "Lar", "organism": "Fruit fly", "refseq_name": "Leukocyte-antigen-related-like, isoform A", "refseq_ac": [ { "id": "NP_523604", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523604", "type": "external" } ], "gene_names_uniprotkb": "Lar; CG10443; DLAR; DLar; Dlar; Dmel\\CG10443; Dmel_CG10443; LAR; PTP38A; Ptp38A; dlar; lar", "gene_names_refseq": "CG10443; DLAR; DLar; Dlar; Dmel\\CG10443; LAR; Lar; PTP38A; Ptp38A; dlar; lar", "protein_names_uniprotkb": "Tyrosine-protein phosphatase Lar; 3.1.3.48; Protein-tyrosine-phosphate phosphohydrolase; dLAR", "protein_names_refseq": "CG10443-PA; LAR receptor tyrosine phosphatase; Lar-PA; Leukocyte-antigen-related-like, isoform A; bypass; leukocyte- antigen-related-like; leukocyte-antigen-related-like", "tax_id": 7227, "disease": "restless legs syndrome (Disease Ontology:DOID:0050425); hypertension (Disease Ontology:DOID:10763); azoospermia (Disease Ontology:DOID:14227); hyperinsulinism (Disease Ontology:DOID:2018); coronary artery disease (Disease Ontology:DOID:3393); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG10443); (R-DME-375165); (R-DME-388844); (R-DME-416700); (R-DME-5673001); (R-DME-6798695); (R-DME-77387); (R-DME-8849932)", "pathway_count": 8, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;21402080;24174674;2554325;25589440;26109356;26109357;8598047", "class_list": "", "function": "Possible cell adhesion receptor (Probable). It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) (PubMed:2554325). It controls motor axon guidance (PubMed:8598047). In the developing eye, has a role in normal axonal targeting of the R7 photoreceptor, where it negatively regulates bdl (PubMed:24174674). Inhibits bdl cell adhesion activity in vitro; this effect is independent of its PTPase function (PubMed:24174674)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 15, "predicted_n_glycosites": 12, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "Q960M3;Q9VIS8", "ec_number_list": [ { "id": "1.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.-", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.2.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.21", "type": "external" }, { "id": "3.2.1.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.46", "type": "external" }, { "id": "3.4.24.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.11", "type": "external" } ], "go_molecular_function": "GO:0032093 SAM domain binding;GO:0005158 insulin receptor binding;GO:0008201 heparin binding;GO:0005001 transmembrane receptor protein tyrosine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0030424 axon;GO:0031252 cell leading edge;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0007283 spermatogenesis;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P16621-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P00522-1", "uniprot_id": [ { "id": "ABL_DROME", "url": "https://www.uniprot.org/uniprot/P00522", "type": "external" } ], "mass": 171588.0, "length": 1620, "protein_name": "Tyrosine-protein kinase Abl", "gene_name": "Abl", "organism": "Fruit fly", "refseq_name": "Abl tyrosine kinase, isoform J", "refseq_ac": [ { "id": "NP_001287085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287085", "type": "external" } ], "gene_names_uniprotkb": "Abl; 4674; ABL-1; ABL; Abl1; AblK; Ableson; Am ABL; C-abl; CG4032; D-Abl; D-abl; D-ash; DAbl; DROTKABL3; Dabl; Dash; Dmel\\CG4032; Dmel_CG4032; Dsrc7; abl1; abl; c-abl; cAbl; dAbl; l(3)04674; l(3)73Ba; l(3)c-abl", "gene_names_refseq": "4674; ABL; Abl1; AblK; Ableson; Abl; Am ABL; C-abl; CG4032; D-Abl; D-abl; D-ash; DAbl; DROTKABL3; Dabl; Dash; Ddash/abl; Dmel\\CG4032; Dsrc7; abl1; abl; c-abl; cAbl; dAbl; l(3)04674; l(3)73Ba; l(3)c-abl", "protein_names_uniprotkb": "Tyrosine-protein kinase Abl; 2.7.10.2; D-ash; Protein abelson", "protein_names_refseq": "Abl oncogene; Abl tyrosine kinase, isoform J; Abl-PJ; CG4032-PJ; D-abelson; abelson kinase; abelson tyrosine kinase; abl kinase", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); stomach cancer (Disease Ontology:DOID:10534); Parkinson's disease (Disease Ontology:DOID:14330); lung non-small cell carcinoma (Disease Ontology:DOID:3908); esophagus adenocarcinoma (Disease Ontology:DOID:4914); ureteral obstruction (Disease Ontology:DOID:5199); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG4032); (R-DME-2029482); (R-DME-428890); (R-DME-525793); (R-DME-5663213); (R-DME-5693565); (R-DME-69231); (R-DME-8939236); (R-DME-9013149); (R-DME-9013423); (R-DME-9841922); (R-DME-9860927)", "pathway_count": 12, "publication_count": 19, "publication_id_list": "10731132;11756472;12537568;12537569;12537572;12537573;12537574;12973825;16110336;17372656;17569856;17569867;25589440;26109356;26109357;2832740;37041188;6317185;9635189", "class_list": "", "function": "Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis; critical for embryonic epithelial morphogenesis regulating cell shape changes and cell migration (PubMed:11756472, PubMed:12973825, PubMed:9635189). Plays a critical role in transducing embryonic midline repulsive cues; may regulate cytoskeletal dynamics underlying a growth cone's response to midline cues (PubMed:12973825). The ability of pCC/MP2 axons to correctly interpret midline repulsive cues and stay on the ipsilateral side is dependent on the strength of both Slit/robo and Abl-dependent signaling pathways (PubMed:12973825). Function in neurons is essential for adult survival, and is important for climbing behavior and activity (PubMed:37041188)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q95TV1;Q9VV86", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" } ], "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030424 axon", "go_biological_process": "GO:0008064 regulation of actin polymerization or depolymerization;GO:0048749 compound eye development;GO:0007409 axonogenesis;GO:0007611 learning or memory;GO:0016199 axon midline choice point recognition", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P00522-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O77237-1", "uniprot_id": [ { "id": "PELI_DROME", "url": "https://www.uniprot.org/uniprot/O77237", "type": "external" } ], "mass": 46770.0, "length": 424, "protein_name": "Protein pellino", "gene_name": "Pli", "organism": "Fruit fly", "refseq_name": "pellino, isoform B", "refseq_ac": [ { "id": "NP_001097890", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097890", "type": "external" } ], "gene_names_uniprotkb": "Pli; CG5212; Dmel\\CG5212; Dmel_CG5212; PAP; PELLINO; pellino; pli", "gene_names_refseq": "CG5212; Dmel\\CG5212; PAP; PELLINO; Pli; pellino; pli", "protein_names_uniprotkb": "Protein pellino", "protein_names_refseq": "CG5212-PB; Pli-PB; pelle associated protein; pellino, isoform B; pellino", "tax_id": 7227, "disease": "colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG5212); (R-DME-9020702); (R-DME-937039); (R-DME-975144)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10330490;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Scaffold protein involved in the Toll signaling pathway via its interaction with pelle/pll kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0019207 kinase regulator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:1905035 negative regulation of antifungal innate immune response;GO:0045087 innate immune response;GO:0000209 protein polyubiquitination;GO:0070936 protein K48-linked ubiquitination;GO:1900425 negative regulation of defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "O77237-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A8JUV0-4", "uniprot_id": [ { "id": "SBNO_DROME", "url": "https://www.uniprot.org/uniprot/A8JUV0", "type": "external" } ], "mass": 180376.0, "length": 1653, "protein_name": "Protein strawberry notch", "gene_name": "sno", "organism": "Fruit fly", "refseq_name": "strawberry notch, isoform B", "refseq_ac": [ { "id": "NP_001096967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096967", "type": "external" } ], "gene_names_uniprotkb": "sno; CG44436", "gene_names_refseq": "CG1903; CG44436; Dmel\\CG44436; Sno; g-l; l(1)11Ea; sno", "protein_names_uniprotkb": "Protein strawberry notch", "protein_names_refseq": "CG44436-PB; glossy-like; sno-PB; strawberry notch, isoform B; strawberry notch", "tax_id": 7227, "disease": "schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG44436)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10731132;11731237;12230979;12537569;12537572;18327897;33925313;40245499;8287794;9171377", "class_list": "", "function": "Notch pathway component, may contribute to the specificity between lateral and inductive Notch signaling pathways in the wing disk. Required during many developmental stages including oogenesis, embryogenesis and imaginal development of the eye, wing and leg. Ebi and sno regulate EGFR-dependent Delta transcription in the developing eye, by antagonizing a repressor function of Suppressor of Hairless (Su(H)). They are required in the R-cells for normal cone cell development., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "A8JUU9;O01940;Q8MZI4;Q95S83;Q9VYF7", "ec_number_list": [], "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045747 positive regulation of Notch signaling pathway;GO:0042461 photoreceptor cell development", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "A8JUV0-4", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P27864-1", "uniprot_id": [ { "id": "RRP1_DROME", "url": "https://www.uniprot.org/uniprot/P27864", "type": "external" } ], "mass": 74635.0, "length": 679, "protein_name": "Recombination repair protein 1", "gene_name": "Rrp1", "organism": "Fruit fly", "refseq_name": "recombination repair protein 1, isoform A", "refseq_ac": [ { "id": "NP_476841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476841", "type": "external" } ], "gene_names_uniprotkb": "Rrp1; 3178; APEX1; CG3178; Dmel\\CG3178; Dmel_CG3178; RRP1_DROME; RRP1; Rrp-1; rrp", "gene_names_refseq": "3178; APEX1; CG3178; Dmel\\CG3178; RRP1_DROME; RRP1; Rrp-1; Rrp1; rrp", "protein_names_uniprotkb": "Recombination repair protein 1; 3.1.11.2; DNA-(apurinic or apyrimidinic site) endonuclease", "protein_names_refseq": "CG3178-PA; Rrp1-PA; recombination repair protein 1, isoform A; recombination repair protein 1; strand transferase", "tax_id": 7227, "disease": "spina bifida (Disease Ontology:DOID:0080016); urinary bladder cancer (Disease Ontology:DOID:11054); severe pre-eclampsia (Disease Ontology:DOID:13129); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); status epilepticus (Disease Ontology:DOID:1824); brain ischemia (Disease Ontology:DOID:2316); ovarian cancer (Disease Ontology:DOID:2394); cervix carcinoma (Disease Ontology:DOID:2893); breast carcinoma (Disease Ontology:DOID:3459); cervical cancer (Disease Ontology:DOID:4362); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); lung disease (Disease Ontology:DOID:850); prostate carcinoma in situ (Disease Ontology:DOID:8634)", "pathway": " (dme:Dmel_CG3178); (R-DME-110357); (R-DME-110373); (R-DME-5651801); (R-DME-73933)", "pathway_count": 5, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;16507570;1653418;1713691;17569856;17569867;18327897;25589440;26109356;26109357;8918793", "class_list": "", "function": "Plays a role in the cellular response to oxidative stress by promoting DNA repair mechanisms such as base excision repair and possibly homologous recombination repair (PubMed:16507570, PubMed:1713691). Functions as an apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents (PubMed:16507570). Likely to initiate repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends (By similarity). Has a 3'-5' exoribonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapped DNA molecules during short-patch BER (PubMed:16507570). Has apurinic endonuclease and double-stranded DNA 3'-exonuclease activities and carries out single-stranded DNA renaturation in a Mg(2+)-dependent manner (PubMed:1713691, PubMed:8918793). Activity is more efficient in purine-rich regions of dsDNA than in pyrimidine-rich regions (PubMed:8918793)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q540Y1;Q9VQJ4", "ec_number_list": [ { "id": "3.1.11.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.2", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.2.2.29", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.29", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "3.2.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.27", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.-", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0070182 DNA polymerase binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008081 phosphoric diester hydrolase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006284 base-excision repair;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P27864-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B7Z073-1", "uniprot_id": [ { "id": "SOSSC_DROME", "url": "https://www.uniprot.org/uniprot/B7Z073", "type": "external" } ], "mass": 13572.0, "length": 129, "protein_name": "SOSS complex subunit C homolog", "gene_name": "CG42374", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_001137972", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137972", "type": "external" } ], "gene_names_uniprotkb": "CG42374", "gene_names_refseq": "CG42374; Dmel\\CG42374; Dromel_CG9666_FBtr0074991_uORF", "protein_names_uniprotkb": "SOSS complex subunit C homolog", "protein_names_refseq": "CG42374-PA; CPuORF of FBgn0036856; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42374)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0070876 SOSS complex", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "B7Z073-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O02194-1", "uniprot_id": [ { "id": "PSN_DROME", "url": "https://www.uniprot.org/uniprot/O02194", "type": "external" } ], "mass": 59304.0, "length": 541, "protein_name": "Presenilin homolog", "gene_name": "Psn", "organism": "Fruit fly", "refseq_name": "presenilin, isoform C", "refseq_ac": [ { "id": "NP_001137988", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137988", "type": "external" } ], "gene_names_uniprotkb": "Psn; 14; 15; CG18803; CG5868; DPS; DPsn; DmPS; Dmel\\CG18803; Dmel_CG18803; Dps; DrosPS; PS1; PSN; PS; dPsn; gamma-secretase; l(3)77CDb; l(3)S048015a; l(3)S049314a; l(3)S049314; pres; psn", "gene_names_refseq": "0480/15; 0493/14; 493/14; CG18803; CG5868; DPS; DPsn; DmPS; Dmel\\CG18803; Dps; DrosPS; PS1; PSN; PS; Psn; dPsn; gamma-secretase; l(3)77CDb; l(3)S048015a; l(3)S049314a; l(3)S049314; pres; psn", "protein_names_uniprotkb": "Presenilin homolog; 3.4.23.-; DmPS; dPS", "protein_names_refseq": "CG18803-PC; Psn-PC; dPresenilin; gamma-secretase component; lethal (3) S048015a; lethal (3) S049314a; pre-senelin; presenilin, isoform C; presenilin", "tax_id": 7227, "disease": "frontotemporal dementia 1 (Disease Ontology:DOID:0051060); early-onset Parkinson's disease (Disease Ontology:DOID:0060894); Alzheimer's disease 4 (Disease Ontology:DOID:0110040); Alzheimer's disease 3 (Disease Ontology:DOID:0110042); dilated cardiomyopathy 1V (Disease Ontology:DOID:0110427); dilated cardiomyopathy 1U (Disease Ontology:DOID:0110455); Alzheimer's disease (Disease Ontology:DOID:10652); Pick's disease (Disease Ontology:DOID:11870); neurodegenerative disease (Disease Ontology:DOID:1289); dilated cardiomyopathy (Disease Ontology:DOID:12930); breast cancer (Disease Ontology:DOID:1612); hidradenitis suppurativa (Disease Ontology:DOID:2280)", "pathway": " (dme:Dmel_CG18803); (R-DME-1251985); (R-DME-3928665); (R-DME-6798695)", "pathway_count": 4, "publication_count": 22, "publication_id_list": "10206646;10206647;10349633;10493744;10662508;10731132;11738826;12537568;12537569;12537572;12537573;12537574;12660785;16110336;17569856;17569867;25589440;26109356;26109357;9106743;9141085;9666900", "class_list": "", "function": "Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptor. Required for S3 cleavage of Notch, which releases activated Notch protein from the cell membrane. Involved in the patterning of the optic lobes., [UniProtKB, PubMed, PubMed, PubMed]; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O02395;O76802;O96340;Q9TY80;Q9V3L9;Q9V3S1", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.4.16.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.16.2", "type": "external" }, { "id": "3.2.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.25", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0042500 aspartic endopeptidase activity, intramembrane cleaving;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0070765 gamma-secretase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0035333 Notch receptor processing, ligand-dependent;GO:0006508 proteolysis;GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0007220 Notch receptor processing", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "O02194-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HJH3-1", "uniprot_id": [ { "id": "SLCB_DROME", "url": "https://www.uniprot.org/uniprot/C0HJH3", "type": "external" } ], "mass": 3409.0, "length": 29, "protein_name": "Sarcolamban B", "gene_name": "SclB", "organism": "Fruit fly", "refseq_name": "sarcolamban B, isoform A", "refseq_ac": [ { "id": "NP_001285990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285990", "type": "external" } ], "gene_names_uniprotkb": "SclB; CG45091", "gene_names_refseq": "BEST:LP06756; BcDNA:RE28911; CG45091; CR31696; Dmel\\CG45091; ORF-B; SCLB; SclB; mel2; pcnr003:2L; pncr003:2L ORFB; pncr003:2L; pncr003; pncr:003:2L; scl", "protein_names_uniprotkb": "Sarcolamban B", "protein_names_refseq": "CG45091-PA; SclB-PA; sarcolamban B, isoform A; sarcolamban", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45091)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;23970561", "class_list": "", "function": "Plays an essential role in the regulation of calcium transport at the sarcoplasmic reticulum (SR), which is secondarily required for regular muscle contraction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SYY2;X2JAM8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0055117 regulation of cardiac muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "C0HJH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HJH4-1", "uniprot_id": [ { "id": "SLCA_DROME", "url": "https://www.uniprot.org/uniprot/C0HJH4", "type": "external" } ], "mass": 3254.0, "length": 28, "protein_name": "Sarcolamban A", "gene_name": "SclA", "organism": "Fruit fly", "refseq_name": "sarcolamban A, isoform A", "refseq_ac": [ { "id": "NP_001285994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285994", "type": "external" } ], "gene_names_uniprotkb": "SclA; CG45090", "gene_names_refseq": "BEST:LP06756; BcDNA:RE28911; CG45090; CR31696; Dmel\\CG45090; ORF-A; SCLA; SclA; mel1; pcnr003:2L; pncr003:2L ORFA; pncr003:2L; pncr003; pncr:003:2L; sclA; scl", "protein_names_uniprotkb": "Sarcolamban A", "protein_names_refseq": "CG45090-PA; SclA-PA; sarcolamban A, isoform A; sarcolamban", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG45090)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;23970561", "class_list": "", "function": "Plays an essential role in the regulation of calcium transport at the sarcoplasmic reticulum (SR), which is secondarily required for regular muscle contraction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SYY2;X2JEE2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030315 T-tubule;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0055117 regulation of cardiac muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "C0HJH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HJX4-1", "uniprot_id": [ { "id": "TAL1A_DROME", "url": "https://www.uniprot.org/uniprot/C0HJX4", "type": "external" } ], "mass": 1229.0, "length": 11, "protein_name": "Peptide tarsal-less 1A", "gene_name": "tal-1A", "organism": "Fruit fly", "refseq_name": "tarsal-less 1A", "refseq_ac": [ { "id": "NP_001138050", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138050", "type": "external" } ], "gene_names_uniprotkb": "tal-1A; CG42384; pri; tal", "gene_names_refseq": "CG42384; Dm1; Dmel\\CG42384; ORF 1A; ORF1; Pep1; Pri; Tal1A; pri; tal-1A; tal", "protein_names_uniprotkb": "Peptide tarsal-less 1A; Peptide polished rice 1", "protein_names_refseq": "CG42384-PB; tal-1A-PB; tarsal-less 1A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42384); (dme:Dmel_CG42385)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10731132;12537572;17439302;17486114;18801356;20647469;21527259;21682860;25344753;26383956", "class_list": "", "function": "One of four peptides (tal-1A, tal-2A, tal-3A and tal-AA) produced from a polycistronic gene that function redundantly in several developmental processes (PubMed:17439302, PubMed:17486114, PubMed:21527259, PubMed:25344753). Required in early stages of leg development for the intercalation of the tarsal segments during the mid-third instar stage and later for tarsal joint formation (PubMed:17439302, PubMed:18801356, PubMed:21527259). Promotes the post-translational modification of ovo isoform B (svb) into its active form which in turn initiates trichome development and promotes tarsal joint development (PubMed:20647469, PubMed:21527259, PubMed:26383956). This is likely due to recruitment of the E3 ubiquitin-protein ligase Ubr3 to svb for ubiquitination of its N-terminus, converting svb into a transcriptional activator (PubMed:26383956). Also enhances interaction of Ubr3 with Diap1 (PubMed:26383956). Required for correct wing and leg formation through its regulation of several genes including those in the Notch signaling pathway (PubMed:18801356, PubMed:21527259, PubMed:21682860). Essential for denticle formation and may have a role in the developmental timing of trichome differentiation (PubMed:17486114, PubMed:25344753). Essential for the development of taenidial folds in the trachea (PubMed:17486114)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A3RLQ8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007015 actin filament organization;GO:0002009 morphogenesis of an epithelium", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "C0HJX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HJX5-1", "uniprot_id": [ { "id": "TAL2A_DROME", "url": "https://www.uniprot.org/uniprot/C0HJX5", "type": "external" } ], "mass": 1229.0, "length": 11, "protein_name": "Peptide tarsal-less 2A", "gene_name": "tal-2A", "organism": "Fruit fly", "refseq_name": "tarsal-less 2A", "refseq_ac": [ { "id": "NP_001138051", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138051", "type": "external" } ], "gene_names_uniprotkb": "tal-2A; CG42385; pri; tal", "gene_names_refseq": "CG42385; Dm2; Dmel\\CG42385; ORF 2A; ORF2; Pep2; Pri; pri; tal-2A; tal", "protein_names_uniprotkb": "Peptide tarsal-less 2A; Peptide polished rice 2", "protein_names_refseq": "CG42385-PA; tal-2A-PA; tarsal-less 2A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42384); (dme:Dmel_CG42385)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537569;12537572;17439302;17486114;18801356;20647469;21527259;21682860;25344753;26383956", "class_list": "", "function": "One of four peptides (tal-1A, tal-2A, tal-3A and tal-AA) produced from a polycistronic gene that function redundantly in several developmental processes (PubMed:17439302, PubMed:17486114, PubMed:21527259, PubMed:25344753). Required in early stages of leg development for the intercalation of the tarsal segments during the mid-third instar stage and later for tarsal joint formation (PubMed:17439302, PubMed:18801356, PubMed:21527259). Promotes the post-translational modification of ovo isoform B (svb) into its active form which in turn initiates trichome development and promotes tarsal joint development (PubMed:20647469, PubMed:21527259, PubMed:26383956). This is likely due to recruitment of the E3 ubiquitin-protein ligase Ubr3 to svb for ubiquitination of its N-terminus, converting svb into a transcriptional activator (PubMed:26383956). Also enhances interaction of Ubr3 with Diap1 (PubMed:26383956). Required for correct wing and leg formation through its regulation of several genes including those in the Notch signaling pathway (PubMed:18801356, PubMed:21527259, PubMed:21682860). Essential for denticle formation and may have a role in the developmental timing of trichome differentiation (PubMed:17486114, PubMed:25344753). Essential for the development of taenidial folds in the trachea (PubMed:17486114)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A3RLQ8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007015 actin filament organization;GO:0002009 morphogenesis of an epithelium", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "C0HJX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HKA0-1", "uniprot_id": [ { "id": "RS14A_DROME", "url": "https://www.uniprot.org/uniprot/C0HKA0", "type": "external" } ], "mass": 16265.0, "length": 151, "protein_name": "Small ribosomal subunit protein uS11A", "gene_name": "RpS14a", "organism": "Fruit fly", "refseq_name": "ribosomal protein S14a, isoform B", "refseq_ac": [ { "id": "NP_524884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524884", "type": "external" } ], "gene_names_uniprotkb": "RpS14a; CG1524", "gene_names_refseq": "CG1524; Dmel\\CG1524; RPS14A; Rp S14a; RpS14A; RpS14a; RpS14; S11; S14a; S14; anon-EST:Posey115; anon-EST:Posey131; anon-EST:Posey154; anon-EST:Posey77; anon-WO03040301.136; anon-WO03040301.138; rpS14A", "protein_names_uniprotkb": "Small ribosomal subunit protein uS11A; 40S ribosomal protein S14a", "protein_names_refseq": "40S ribosomal protein S14; CG1524-PB; RpS14a-PB; ribosomal protein S14a, isoform B", "tax_id": 7227, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); chromosome 5q deletion syndrome (Disease Ontology:DOID:0090016); anemia (Disease Ontology:DOID:2355)", "pathway": " (dme:Dmel_CG1524); (dme:Dmel_CG1527); (R-DME-156827); (R-DME-1799339); (R-DME-6791226); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 14, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23636399;3141788", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P14130;Q0KHV1;Q8SZL7;Q9V3R5", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "C0HKA0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HKA1-1", "uniprot_id": [ { "id": "RS14B_DROME", "url": "https://www.uniprot.org/uniprot/C0HKA1", "type": "external" } ], "mass": 16265.0, "length": 151, "protein_name": "Small ribosomal subunit protein uS11B", "gene_name": "RpS14b", "organism": "Fruit fly", "refseq_name": "ribosomal protein S14b, isoform B", "refseq_ac": [ { "id": "NP_001284995", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284995", "type": "external" } ], "gene_names_uniprotkb": "RpS14b; CG1527; Dmel\\CG1527; Dmel_CG1527; RPS14B; RpS14B; RpS14; S11; S14b; S14; anon-EST:Posey115; anon-EST:Posey131; anon-EST:Posey154; anon-EST:Posey77; rpS14B", "gene_names_refseq": "CG1527; Dmel\\CG1527; RPS14B; RpS14B; RpS14b; RpS14; S11; S14b; S14; anon-EST:Posey115; anon-EST:Posey131; anon-EST:Posey154; anon-EST:Posey77; rpS14B", "protein_names_uniprotkb": "Small ribosomal subunit protein uS11B; 40S ribosomal protein S14b", "protein_names_refseq": "CG1527-PB; RpS14b-PB; ribosomal protein S14b, isoform B", "tax_id": 7227, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); chromosome 5q deletion syndrome (Disease Ontology:DOID:0090016); anemia (Disease Ontology:DOID:2355)", "pathway": " (dme:Dmel_CG1524); (dme:Dmel_CG1527); (R-DME-156827); (R-DME-1799339); (R-DME-6791226); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 14, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;3141788", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P14130;Q0KHV1;Q8SZL7;Q9V3R5", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "C0HKA1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "C0HKF7-1", "uniprot_id": [ { "id": "SER1_DROME", "url": "https://www.uniprot.org/uniprot/C0HKF7", "type": "external" } ], "mass": 28469.0, "length": 265, "protein_name": "Serine protease 1", "gene_name": "Jon99Cii", "organism": "Fruit fly", "refseq_name": "jonah 99Cii", "refseq_ac": [ { "id": "NP_524554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524554", "type": "external" } ], "gene_names_uniprotkb": "Jon99Cii; CG7877; SER1; Ser99Da", "gene_names_refseq": "99Calpha; CG31034; CG7877; Dmel\\CG31034; Jon99B; Jon99C1; Jon99C2; Jon99Calphai; Jon99Calpha; Jon99Cbetaii; Jon99Cbeta; Jon99Ciii; Jon99Cii; Jon99C; JonC; SER1; SP122; Ser1; Ser5; Ser99Da; Serl", "protein_names_uniprotkb": "Serine protease 1; 3.4.21.-; Protein Jonah 99Cii", "protein_names_refseq": "CG31034-PA; Jon99Cii-PA; jonah 99C alpha; jonah 99C beta; jonah 99Cii; serine protease 1; serine protease 5", "tax_id": 7227, "disease": "pancreatitis (Disease Ontology:DOID:4989)", "pathway": " (dme:Dmel_CG31034); (dme:Dmel_CG31362)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;2469005", "class_list": "", "function": "Major function may be to aid in digestion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P17205;Q23988;Q9VAD9;Q9VAE0", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0017171 serine hydrolase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "C0HKF7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P15330-1", "uniprot_id": [ { "id": "DORS_DROME", "url": "https://www.uniprot.org/uniprot/P15330", "type": "external" } ], "mass": 111551.0, "length": 999, "protein_name": "Embryonic polarity protein dorsal", "gene_name": "dl", "organism": "Fruit fly", "refseq_name": "dorsal, isoform D", "refseq_ac": [ { "id": "NP_001163000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163000", "type": "external" } ], "gene_names_uniprotkb": "dl; CG6667; DL; Dl; Dmel\\CG6667; Dmel_CG6667; Dorsal; Dor; GSd447; NF-KB; NF-kappaB; NFkappaB; anon-EST:GressD7; dL; fs(2)k10816; mat(2)dorsal; p65", "gene_names_refseq": "CG6667; DL; Dl; Dmel\\CG6667; Dorsal; Dor; GSd447; NF-KB; NF-kappaB; NFkappaB; anon-EST:GressD7; dL; dl; fs(2)k10816; mat(2)dorsal; p65", "protein_names_uniprotkb": "Embryonic polarity protein dorsal", "protein_names_refseq": "CG6667-PD; DORSAL; Dorsal/NF-kappaB; NFkappabeta; dl-PD; dorsal, isoform D; embryonic polarity protein dorsal", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); obstructive sleep apnea (Disease Ontology:DOID:0050848); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); lymphoma (Disease Ontology:DOID:0060058); ductal carcinoma in situ (Disease Ontology:DOID:0060074); colitis (Disease Ontology:DOID:0060180); mastoiditis (Disease Ontology:DOID:0060322); immunodeficiency 92 (Disease Ontology:DOID:0061062); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); Parkinsonism (Disease Ontology:DOID:0080855); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); immunodeficiency 53 (Disease Ontology:DOID:0111992); otitis media (Disease Ontology:DOID:10754); hypertension (Disease Ontology:DOID:10763); cholesteatoma of middle ear (Disease Ontology:DOID:10964); urinary bladder cancer (Disease Ontology:DOID:11054); prostatic hypertrophy (Disease Ontology:DOID:11132); primary biliary cholangitis (Disease Ontology:DOID:12236); uveitis (Disease Ontology:DOID:13141); renovascular hypertension (Disease Ontology:DOID:1591); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); arteriosclerosis (Disease Ontology:DOID:2349); prostate adenocarcinoma (Disease Ontology:DOID:2526); transitional cell carcinoma (Disease Ontology:DOID:2671); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); lung non-small cell carcinoma (Disease Ontology:DOID:3908); renal cell carcinoma (Disease Ontology:DOID:4450); liver cirrhosis (Disease Ontology:DOID:5082); pulmonary hypertension (Disease Ontology:DOID:6432); end stage renal disease (Disease Ontology:DOID:783); prostate carcinoma in situ (Disease Ontology:DOID:8634); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); steatotic liver disease (Disease Ontology:DOID:9452); encephalitis (Disease Ontology:DOID:9588); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG6667); (R-DME-1169091); (R-DME-1810476); (R-DME-202424); (R-DME-209400); (R-DME-209406); (R-DME-209560); (R-DME-214842); (R-DME-214844); (R-DME-214869); (R-DME-2871837); (R-DME-3134963); (R-DME-445989); (R-DME-4755510); (R-DME-5607761); (R-DME-5607764); (R-DME-5621575); (R-DME-5676590); (R-DME-9020702); (R-DME-933542); (R-DME-9860927); (R-DME-9958825)", "pathway_count": 22, "publication_count": 37, "publication_id_list": "10072384;10072776;10197979;10369678;10660298;10731132;10843389;11532919;12537568;12537572;12537573;12537574;12653959;12973300;14638854;16110336;17032737;17569856;17569867;18000549;25477468;25589440;2598266;26109356;26109357;30982648;3118464;7705656;7859742;8808632;8948598;9025065;9367441;9405646;9405661;9553105;9990853", "class_list": "", "function": "Embryonic developmental transcription factor (PubMed:10072776, PubMed:2598266, PubMed:30982648). The lateral or ventral identity of a cell depends upon the concentration of this protein in its nucleus during the blastoderm stage (PubMed:2598266). Acts as a morphogenetic transcription factor that specifically binds to the kappa-B-related consensus sequence 5'-GRGAAAANCC-3', located in the enhancer region of zygotic genes such as Zen, Twist, Snail and Decapentaplegic, promoting their expression (PubMed:10072776, PubMed:2598266, PubMed:30982648). Part of a signaling pathway involving NF-kappa-B and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition (PubMed:25477468). Mediates an immune response in larvae (PubMed:10072776). May be part of a NF-kappa-B and Tollo signaling cascade that regulates development of the peripheral nervous system (PubMed:18000549)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 38, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O77088;Q0E8P9;Q6AWP3;Q9VJD9;Q9VJE0", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 3.8, "record_id": "P15330-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O97148-1", "uniprot_id": [ { "id": "MTH_DROME", "url": "https://www.uniprot.org/uniprot/O97148", "type": "external" } ], "mass": 59644.0, "length": 514, "protein_name": "G protein-coupled receptor Mth", "gene_name": "mth", "organism": "Fruit fly", "refseq_name": "methuselah, isoform E", "refseq_ac": [ { "id": "NP_001246535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246535", "type": "external" } ], "gene_names_uniprotkb": "mth; CG6936; Dmel\\CG6936; Dmel_CG6936; MTH; Mth", "gene_names_refseq": "CG6936; Dmel\\CG6936; MTH; Mth; mth", "protein_names_uniprotkb": "G protein-coupled receptor Mth; Protein methuselah", "protein_names_refseq": "CG6936-PE; methusalah; methuselah, isoform E; methuselah; mth-PE", "tax_id": 7227, "disease": "alcohol-related neurodevelopmental disorder (Disease Ontology:DOID:0050667)", "pathway": " (dme:Dmel_CG6936)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10731132;10995474;11274391;12367510;12537568;12537569;12537572;12537573;12537574;15133470;16110336;17546039;17569856;17569867;19672878;25589440;26109356;26109357;9794765", "class_list": "", "function": "Involved in biological aging and stress response. Essential for adult survival. Required in the presynaptic motor neuron to up-regulate neurotransmitter exocytosis at larval glutamatergic neuromuscular junctions (NMJs). Regulates a step associated with docking and clustering of vesicles at release sites. SP/Acp70A and sun are agonists that activate mth in vitro., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "B5RJF9;Q9GN21;Q9GN78;Q9GND6;Q9GNE8;Q9GT57;Q9GT58;Q9GT59;Q9GT60;Q9W0R4", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008528 G protein-coupled peptide receptor activity;GO:0042277 peptide binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0098793 presynapse", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0042594 response to starvation;GO:0000302 response to reactive oxygen species;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "O97148-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.1000000010000.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22270-1", "uniprot_id": [ { "id": "OAR_DROME", "url": "https://www.uniprot.org/uniprot/P22270", "type": "external" } ], "mass": 64674.0, "length": 601, "protein_name": "Tyramine/octopamine receptor", "gene_name": "Oct-TyrR", "organism": "Fruit fly", "refseq_name": "Octopamine-Tyramine receptor, isoform B", "refseq_ac": [ { "id": "NP_001163494", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163494", "type": "external" } ], "gene_names_uniprotkb": "Oct-TyrR; CG7485; DmTAR1; DmTyrR; Dmel\\CG7485; Dmel_CG7485; DrmOTR; OA-R; OAR_DROME; OTR; OcR; Ocr; OctoR1; OctyR99AB; TAR1; TYR; TyR; Tyr-OctR; Tyr-dro; TyrR; Tyr; hono; l(3)neo30; tar1; tyr", "gene_names_refseq": "CG7485; DmTAR1; DmTyrR; Dmel\\CG7485; Dmoct/tyr; DrmOTR; OA-R; OAR_DROME; OTR; OcR; Ocr; Oct-TyrR; Oct/Tyr; OctoR1; OctyR99AB; TAR1; TYR; TyR; Tyr-OctR; Tyr-dro; TyrR; Tyr; hono; l(3)neo30; tar1", "protein_names_uniprotkb": "Tyramine/octopamine receptor; Tyr/Oct-Dro", "protein_names_refseq": "CG7485-PB; Oct-TyrR-PB; Oct/Tyr receptor; Octopamine-Tyramine receptor, isoform B; Tyramine-receptor; honoka; octopamine receptor 1; octopamine/tyramine receptor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7485); (R-DME-390696); (R-DME-392023); (R-DME-400042); (R-DME-418594); (R-DME-418597)", "pathway_count": 6, "publication_count": 14, "publication_id_list": "10713442;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;2156539;2170118;25589440;26109356;26109357", "class_list": "", "function": "Receptor for both octopamine and tyramine, invertebrate neurotransmitters, and neuromodulators. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The rank order of potency for agonists is tyramine > octopamine > dopamine > epinephrine > norepinephrine > serotonin > histamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > cyproheptadine > dihydroergotamine > clonidine > synephrine. Tyramine has a functional role in the olfactory system as a neurotransmitter or a neuromodulator., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q1RKQ4;Q95YF4;Q9VNW3", "ec_number_list": [], "go_molecular_function": "GO:0008227 G protein-coupled amine receptor activity;GO:0004989 octopamine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007608 sensory perception of smell;GO:1900738 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007211 octopamine or tyramine signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P22270-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JI63-1", "uniprot_id": [ { "id": "SNMP2_DROME", "url": "https://www.uniprot.org/uniprot/E1JI63", "type": "external" } ], "mass": 62634.0, "length": 556, "protein_name": "Sensory neuron membrane protein 2", "gene_name": "Snmp2", "organism": "Fruit fly", "refseq_name": "sensory neuron membrane protein 2, isoform B", "refseq_ac": [ { "id": "NP_001036593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036593", "type": "external" } ], "gene_names_uniprotkb": "Snmp2; CG7422", "gene_names_refseq": "148358_at; CG16832; CG7422; Dmel\\CG7422; SNMP2; Snmp2; snmp", "protein_names_uniprotkb": "Sensory neuron membrane protein 2; SNMP2Dmel", "protein_names_refseq": "CG7422-PB; Snmp2-PB; sensory neuron membrane protein 2, isoform B", "tax_id": 7227, "disease": "rheumatic heart disease (Disease Ontology:DOID:0050827); atrial fibrillation (Disease Ontology:DOID:0060224); myeloid neoplasm (Disease Ontology:DOID:0070004); platelet-type bleeding disorder 10 (Disease Ontology:DOID:0111046); progressive myoclonus epilepsy 4 (Disease Ontology:DOID:0111444); dermatomyositis (Disease Ontology:DOID:10223); silicosis (Disease Ontology:DOID:10325); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); thrombotic thrombocytopenic purpura (Disease Ontology:DOID:10772); sickle cell anemia (Disease Ontology:DOID:10923); polycystic ovary syndrome (Disease Ontology:DOID:11612); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); granulomatosis with polyangiitis (Disease Ontology:DOID:12132); malaria (Disease Ontology:DOID:12365); hemolytic-uremic syndrome (Disease Ontology:DOID:12554); atherosclerosis (Disease Ontology:DOID:1936); blood platelet disease (Disease Ontology:DOID:2218); essential thrombocythemia (Disease Ontology:DOID:2224); arteriosclerosis (Disease Ontology:DOID:2349); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); nephrosis (Disease Ontology:DOID:2527); endometriosis (Disease Ontology:DOID:289); pulmonary tuberculosis (Disease Ontology:DOID:2957); inclusion body myositis (Disease Ontology:DOID:3429); pulmonary fibrosis (Disease Ontology:DOID:3770); macular degeneration (Disease Ontology:DOID:4448); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); osteoarthritis (Disease Ontology:DOID:8398); chronic myeloid leukemia (Disease Ontology:DOID:8552); progressive myoclonus epilepsy (Disease Ontology:DOID:891); polycythemia vera (Disease Ontology:DOID:8997); pemphigus (Disease Ontology:DOID:9182); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG7422); (R-DME-114608); (R-DME-1236973); (R-DME-434313); (R-DME-6798695)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537572;19364529", "class_list": "", "function": "Plays an olfactory role that is not restricted to pheromone sensitivity., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 36, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A0AVW0;A1A6X6;A1A6X7;A1A6Z5;A1A6Z6;A2RVH7;A8W3N7;C9QPB5;Q0E8H2", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007608 sensory perception of smell;GO:0071444 cellular response to pheromone", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "E1JI63-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P29503-1", "uniprot_id": [ { "id": "NEUR_DROME", "url": "https://www.uniprot.org/uniprot/P29503", "type": "external" } ], "mass": 82325.0, "length": 754, "protein_name": "Protein neuralized", "gene_name": "neur", "organism": "Fruit fly", "refseq_name": "neuralized, isoform E", "refseq_ac": [ { "id": "NP_001163563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163563", "type": "external" } ], "gene_names_uniprotkb": "neur; 05; 09; 12; 15; BEST:LD21494; CG11988; Dmel\\CG11988; Dmel_CG11988; Neur; l(3)j6B12; l(3)j9B8; l(3)j9B9; l(3)j9C8; l(3)neo37; neu", "gene_names_refseq": "0328/12; 0971/15; 1293/09; 1315/05; BEST:LD21494; CG11988; Dmel\\CG11988; Neur; l(3)j6B12; l(3)j9B8; l(3)j9B9; l(3)j9C8; l(3)neo37; neur; neu", "protein_names_uniprotkb": "Protein neuralized", "protein_names_refseq": "CG11988-PE; neur-PE; neuralised; neuralized, isoform E; neuralized", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11988)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15760269;15829515;16110336;1717258;17569856;17569867;18327897;25589440;26109356;26109357;8508767", "class_list": "", "function": "Probable E3 ubiquitin-protein ligase involved in regulation of Notch signaling (PubMed:15760269, PubMed:15829515). May ubiquitinate the intracellular domains of Notch ligands Dl/delta and Ser/serrate, leading to their endocytosis and degradation (PubMed:15760269, PubMed:15829515). Involved in neurogenesis. Interacts with other neurogenic proteins in the specification of the neuroblast versus epidermoblast cell fate., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q26306;Q27273;Q8INP6;Q8INP7;Q960M1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:1901981 phosphatidylinositol phosphate binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0048749 compound eye development;GO:0007399 nervous system development;GO:0045747 positive regulation of Notch signaling pathway;GO:0007422 peripheral nervous system development;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P29503-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20193-1", "uniprot_id": [ { "id": "SUV37_DROME", "url": "https://www.uniprot.org/uniprot/P20193", "type": "external" } ], "mass": 139990.0, "length": 1250, "protein_name": "Protein suppressor of variegation 3-7", "gene_name": "Su(var)3-7", "organism": "Fruit fly", "refseq_name": "suppressor of variegation 3-7, isoform A", "refseq_ac": [ { "id": "NP_524342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524342", "type": "external" } ], "gene_names_uniprotkb": "Su(var)3-7; CG8599; DmSu(var)3-7; Dmel\\CG8599; Dmel_CG8599; SU(VAR)3-7; Su(Var)3-7; Su(var)(3)3; Su(var)(3)7; Su-var(3)7; Suv3-7; Suvar(3)7; Suvar37; l(3)87El", "gene_names_refseq": "CG8599; DmSu(var)3-7; Dmel\\CG8599; SU(VAR)3-7; Su(Var)3-7; Su(var)(3)3; Su(var)(3)7; Su(var)3-7; Su-var(3)7; Suv3-7; Suvar(3)7; Suvar37; l(3)87El", "protein_names_uniprotkb": "Protein suppressor of variegation 3-7", "protein_names_refseq": "CG8599-PA; Su(var)3-7-PA; suppressor of variegation 3-7, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8599)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;11867540;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18327897;2107402;25589440;26109356;26109357;7708496", "class_list": "", "function": "Dose-limiting factor in position-effect variegation, the inactivation in some cells of a gene translocated next to heterochromatin. It could play a role in chromosome condensation., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFX7", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000792 heterochromatin;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0031453 positive regulation of heterochromatin formation;GO:0009047 dosage compensation by hyperactivation of X chromosome;GO:0090053 positive regulation of pericentric heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P20193-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E1JIT7-1", "uniprot_id": [ { "id": "PSD_DROME", "url": "https://www.uniprot.org/uniprot/E1JIT7", "type": "external" } ], "mass": 176440.0, "length": 1601, "protein_name": "PH and SEC7 domain-containing protein", "gene_name": "Efa6", "organism": "Fruit fly", "refseq_name": "exchange factor for Arf 6, isoform C", "refseq_ac": [ { "id": "NP_001097873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097873", "type": "external" } ], "gene_names_uniprotkb": "Efa6; CG18185; CG31158; CG6941; dPsd", "gene_names_refseq": "CG18185; CG31158; CG6941; Dmel\\CG31158; EFA6; Efa6; dEfa6; dPsd; efa6", "protein_names_uniprotkb": "PH and SEC7 domain-containing protein; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6; Exchange factor for Arf 6", "protein_names_refseq": "CG31158-PC; Efa6 pleckstrin and Sec7 domain containing; Efa6-PC; exchange factor for Arf 6 ortholog; exchange factor for Arf 6, isoform C", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG31158)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;28607459;31718774", "class_list": "", "function": "Guanine nucleotide exchange factor for Arf6 (PubMed:28607459). Regulates axon growth and branching by inhibiting microtubule polymerization at the cortex (PubMed:31718774). Together with shot, promotes axonal microtubule bundle integrity (PubMed:31718774). Required for normal ethanol-induced tolerance and preference (PubMed:28607459). Probably by activating Arf6, counteracts ethanol-induced sedation (PubMed:28607459)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8JR81;A8JR82;A8WHG2;C0PUX2;E2QD55;E2QD56;Q8MRV5", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008017 microtubule binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005938 cell cortex;GO:0030424 axon;GO:0044297 cell body;GO:0032587 ruffle membrane", "go_biological_process": "GO:0097305 response to alcohol;GO:0016192 vesicle-mediated transport;GO:0035082 axoneme assembly;GO:0031115 negative regulation of microtubule polymerization;GO:0032014 positive regulation of ARF protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "E1JIT7-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O62618-1", "uniprot_id": [ { "id": "MK38A_DROME", "url": "https://www.uniprot.org/uniprot/O62618", "type": "external" } ], "mass": 42256.0, "length": 366, "protein_name": "Mitogen-activated protein kinase p38a", "gene_name": "p38a", "organism": "Fruit fly", "refseq_name": "p38a MAP kinase, isoform C", "refseq_ac": [ { "id": "NP_001163711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163711", "type": "external" } ], "gene_names_uniprotkb": "p38a; CG5475; D-MPK2; D-P38a; D-p38 MAPK; D-p38a; D-p38; DMPK2; DmMPK2; Dmel\\CG5475; Dmel_CG5475; Dmp38a; Dp38a; Dp38; ERK2; Erk2; MAPK-2; MAPK2; MPK2; Mpk2; P38; dERK2; dMPK2; dp38a; dp38; group 2; mpk2; p38 MAPK; p38 alpha; p38A; p38Ka; p38K; p38MAPK; p38[MAPK]; p38alpha; p38", "gene_names_refseq": "CG5475; D-MPK2; D-P38a; D-p38 MAPK; D-p38a; D-p38; DMPK2; DmMPK2; Dmel\\CG5475; Dmp38a; Dp38a; Dp38; ERK2; Erk2; MAPK-2; MAPK2; MPK2; Mpk2; P38; dERK2; dMPK2; dp38a; dp38; group 2; mpk2; p38 MAPK; p38 alpha; p38A; p38Ka; p38K; p38MAPK; p38[MAPK]; p38alpha; p38a; p38", "protein_names_uniprotkb": "Mitogen-activated protein kinase p38a; 2.7.11.24; MAP kinase 14A; MAP kinase p38a; MAPK p38a; p38 MAPK", "protein_names_refseq": "CG5475-PC; Erk-kinase-like; Mpk2; p38 MAP kinase; p38 mitogen-activated protein kinase; p38a MAP kinase, isoform C; p38a-PC; stress-activated kinase P38", "tax_id": 7227, "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); Alzheimer's disease (Disease Ontology:DOID:10652); osteoporosis (Disease Ontology:DOID:11476); interstitial cystitis (Disease Ontology:DOID:13949); Parkinson's disease (Disease Ontology:DOID:14330); rectum cancer (Disease Ontology:DOID:1993); colon cancer (Disease Ontology:DOID:219); gastric adenocarcinoma (Disease Ontology:DOID:3717); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); nasopharynx carcinoma (Disease Ontology:DOID:9261); diabetic neuropathy (Disease Ontology:DOID:9743)", "pathway": " (dme:Dmel_CG5475); (R-DME-168638); (R-DME-171007); (R-DME-198753); (R-DME-2559580); (R-DME-4420097); (R-DME-450302); (R-DME-450341); (R-DME-525793); (R-DME-5675221); (R-DME-69601)", "pathway_count": 11, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1378625;16110336;17569856;17569867;25589440;26109356;26109357;9417090;9584193", "class_list": "", "function": "Kinase involved in a signal transduction pathway. May down-regulate insect immunity gene expression after prolonged infection., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V3C0;O46216;Q9TXB4", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006955 immune response;GO:0006970 response to osmotic stress;GO:0006979 response to oxidative stress;GO:0035556 intracellular signal transduction;GO:0042594 response to starvation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "O62618-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O97394-1", "uniprot_id": [ { "id": "SDK_DROME", "url": "https://www.uniprot.org/uniprot/O97394", "type": "external" } ], "mass": 246254.0, "length": 2224, "protein_name": "Protein sidekick", "gene_name": "sdk", "organism": "Fruit fly", "refseq_name": "sidekick, isoform E", "refseq_ac": [ { "id": "NP_001162630", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162630", "type": "external" } ], "gene_names_uniprotkb": "sdk; BcDNA:LD22322; BcDNA:RE63453; CG5227; CT16627; Dmel\\CG5227; Dmel_CG5227; EG:BACR19J1.1; Sdk; Sidekick", "gene_names_refseq": "BcDNA:LD22322; BcDNA:RE63453; CG5227; CT16627; Dmel\\CG5227; EG:BACR19J1.1; Sdk; Sidekick; sdk", "protein_names_uniprotkb": "Protein sidekick", "protein_names_refseq": "CG5227-PE; sdk-PE; sidekick, isoform E; sidekick", "tax_id": 7227, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG5227)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;10731137;12537568;12537572;12537573;12537574;16110336;17569856;17569867;17893096;18327897;25589440;26109356;26109357;9310325", "class_list": "", "function": "Participates in homotypic or heterotypic interactions in the eye during pattern formation to prevent extra cells from joining the precluster and differentiating as photoreceptor cells., [UniProtKB, PubMed]", "predicted_glycosites": 25, "predicted_n_glycosites": 24, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 26, "binding_glycan_count": 0, "secondary_ac_list": "A4V3T7;A9UNG5;Q0KHX5;Q86BQ7;Q9U1M1;Q9UB11;Q9W5D9", "ec_number_list": [], "go_molecular_function": "GO:0004895 cell adhesion receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045177 apical part of cell;GO:0098595 perivitelline space;GO:0016020 membrane", "go_biological_process": "GO:0046533 negative regulation of photoreceptor cell differentiation;GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050931 pigment cell differentiation;GO:0042675 compound eye cone cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "O97394-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.1000000011001.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43125-1", "uniprot_id": [ { "id": "RDGB_DROME", "url": "https://www.uniprot.org/uniprot/P43125", "type": "external" } ], "mass": 138895.0, "length": 1259, "protein_name": "Protein retinal degeneration B", "gene_name": "rdgB", "organism": "Fruit fly", "refseq_name": "retinal degeneration B, isoform D", "refseq_ac": [ { "id": "NP_001014740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014740", "type": "external" } ], "gene_names_uniprotkb": "rdgB; CG11111; Dmel\\CG11111; Dmel_CG11111; DrdgBalpha; DrdgB; RDGBalpha; RDGB; RdgBalpha; RdgB; hypoF; ota1; rdbB(ota1); rdgBalpha; x36", "gene_names_refseq": "CG11111; Dmel\\CG11111; DrdgBalpha; DrdgB; RDGBalpha; RDGB; RdgBalpha; RdgB; hypoF; ota1; rdbB(ota1); rdgBalpha; rdgB; x36", "protein_names_uniprotkb": "Protein retinal degeneration B; Probable calcium transporter rdgB", "protein_names_refseq": "CG11111-PD; rdgB-PD; receptor degeneration B; receptor-degeneration-II; retinal degeneration B, isoform D", "tax_id": 7227, "disease": "cone-rod dystrophy 5 (Disease Ontology:DOID:0111010)", "pathway": " (dme:Dmel_CG11111); (R-DME-1483226)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;1903119;22822086;25589440;26109356;26109357;9680295", "class_list": "", "function": "Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes (PubMed:22822086). May control phosphatidylinositol concentration in transport vesicles from the subrhabdomeric cisternae (SRC) to the rhabdomere (PubMed:1903119). May function as a calcium transporter (PubMed:1903119)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V4E8;O02434;Q6NP01;Q961R2;Q9VY88", "ec_number_list": [], "go_molecular_function": "GO:1990050 phosphatidic acid transfer activity;GO:0046872 metal ion binding;GO:0031210 phosphatidylcholine binding;GO:0035091 phosphatidylinositol binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016029 subrhabdomeral cisterna", "go_biological_process": "GO:0006816 calcium ion transport;GO:0007601 visual perception;GO:0007603 phototransduction, visible light;GO:0015914 phospholipid transport;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P43125-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39018-1", "uniprot_id": [ { "id": "RS19A_DROME", "url": "https://www.uniprot.org/uniprot/P39018", "type": "external" } ], "mass": 17291.0, "length": 156, "protein_name": "Small ribosomal subunit protein eS19A", "gene_name": "RpS19a", "organism": "Fruit fly", "refseq_name": "ribosomal protein S19a, isoform D", "refseq_ac": [ { "id": "NP_001285338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285338", "type": "external" } ], "gene_names_uniprotkb": "RpS19a; BcDNA:GM26647; CG4464; Dmel\\CG4464; Dmel_CG4464; RPS19a; Rp S19a; RpS19; S19a; S19e; S19; rpS19", "gene_names_refseq": "BcDNA:GM26647; CG4464; Dmel\\CG4464; RPS19a; Rp S19a; RpS19a; RpS19; S19a; S19e; S19; rpS19", "protein_names_uniprotkb": "Small ribosomal subunit protein eS19A; 40S ribosomal protein S19a", "protein_names_refseq": "CG4464-PD; RpS19a-PD; ribosomal protein S19a, isoform D; ribosomal protein S19", "tax_id": 7227, "disease": "Diamond-Blackfan anemia 1 (Disease Ontology:DOID:0111895); aplastic anemia (Disease Ontology:DOID:12449); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (dme:Dmel_CG4464); (R-DME-156827); (R-DME-1799339); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 12, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;40245499;8367309", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V4N1;B7Z0Y8;Q9VXE1", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P39018-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40423-1", "uniprot_id": [ { "id": "SQH_DROME", "url": "https://www.uniprot.org/uniprot/P40423", "type": "external" } ], "mass": 19954.0, "length": 174, "protein_name": "Myosin regulatory light chain sqh", "gene_name": "sqh", "organism": "Fruit fly", "refseq_name": "spaghetti squash, isoform B", "refseq_ac": [ { "id": "NP_001284928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284928", "type": "external" } ], "gene_names_uniprotkb": "sqh; CG3595; DmMRLC_C; Dmel\\CG3595; Dmel_CG3595; MLC; MLRC; MRLC; Myo II; Myo-II RLC; Myo-II; MyoII; Myosin II; Myo; NMM; RLC2; RLC; RMLC; Sqh; actomyosin; myo II; myo-II; myoII; myosin 2; myosin II; myosin; pMyo-II; sgh; spg; squ; ssq", "gene_names_refseq": "CG3595; DmMRLC_C; Dmel\\CG3595; MLC; MLRC; MRLC; Myo II; Myo-II RLC; Myo-II; MyoII; Myosin II; Myo; NMM; RLC2; RLC; RMLC; Sqh; actomyosin; myo II; myo-II; myoII; myosin 2; myosin II; myosin; pMyo-II; sgh; spg; sqh; squ; ssq", "protein_names_uniprotkb": "Myosin regulatory light chain sqh; MRLC-C; Myosin regulatory light chain, nonmuscle; Protein spaghetti-squash", "protein_names_refseq": "CG3595-PB; Myo-II regulatory light chain; MyoII regulatory light chain; MyoII; Myosin-II light chain; Spaghetti-Squash; actomyosin; myosin 2; myosin II RLC; myosin II regulatory subunit; myosin LC; myosin regulatory light chain; myosinII; non-muscle myosin II regulatory light chain; non-muscle myosin-II; nonmuscle MyoII; nonmuscle myosin II regulatory light chain; phospho-Myosin light chain 2; regulatory light chain of myosin II; regulatory light chain of myosin; regulatory light chain of nonmuscle myosin II; regulatory light chain of nonmuscle myosin-II; regulatory myosin light chain; spaghetti squash, isoform B; spaghetti squash; sqh-PB; type II myosin regulatory light chain", "tax_id": 7227, "disease": "megacystis-microcolon-intestinal hypoperistalsis syndrome (Disease Ontology:DOID:0060610); familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326)", "pathway": " (dme:Dmel_CG3595); (R-DME-350416); (R-DME-350480); (R-DME-3928664); (R-DME-445355)", "pathway_count": 5, "publication_count": 19, "publication_id_list": "10570971;10731132;11301004;11874917;12537568;12537569;12537572;12537573;12537574;15269282;16110336;17372656;17569856;17569867;18327897;1905980;25589440;26109356;26109357", "class_list": "", "function": "Required for cytokinesis, could regulate contractile ring function., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q540V2;Q9W428", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0001671 ATPase activator activity;GO:0032036 myosin heavy chain binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0009791 post-embryonic development;GO:0030048 actin filament-based movement;GO:0000281 mitotic cytokinesis;GO:0045199 maintenance of epithelial cell apical/basal polarity", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40423-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O77277-1", "uniprot_id": [ { "id": "TORS_DROME", "url": "https://www.uniprot.org/uniprot/O77277", "type": "external" } ], "mass": 38170.0, "length": 340, "protein_name": "Torsin-like protein", "gene_name": "Torsin", "organism": "Fruit fly", "refseq_name": "torsin, isoform B", "refseq_ac": [ { "id": "NP_001284866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284866", "type": "external" } ], "gene_names_uniprotkb": "Torsin; CG3024; DTor; DmTorp4a; Dmel\\CG3024; Dmel_CG3024; EG:84H4.1; TORP4A; Torp4a; dTor; dtorsin; dtor; torp4a; torsin", "gene_names_refseq": "CG3024; DTor; DmTorp4a; Dmel\\CG3024; EG:84H4.1; TORP4A; Torp4a; Torsin; dTor; dtorsin; dtor; torp4a; torsin", "protein_names_uniprotkb": "Torsin-like protein", "protein_names_refseq": "CG3024-PB; Torsin-PB; dtorsin; torp4a; torsin, isoform B; torsin", "tax_id": 7227, "disease": "focal dystonia (Disease Ontology:DOID:0050836); torsion dystonia 1 (Disease Ontology:DOID:0060730); arthrogryposis multiplex congenita-5 (Disease Ontology:DOID:0080981); Parkinson's disease (Disease Ontology:DOID:14330); dystonia (Disease Ontology:DOID:543)", "pathway": " (dme:Dmel_CG3024); (R-DME-114608); (R-DME-8856825)", "pathway_count": 3, "publication_count": 15, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18477586;19126864;25589440;26109356;26109357", "class_list": "", "function": "May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "B4F5H4;B4F5H5;B4F5H6;B4F5I2;C0MLF3;C0MLF6;C0MLG2;Q8T037", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0106083 nuclear membrane protein complex", "go_biological_process": "GO:0008057 eye pigment granule organization;GO:0006629 lipid metabolic process;GO:0030307 positive regulation of cell growth;GO:0070050 neuron cellular homeostasis;GO:0042053 regulation of dopamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "O77277-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G5CKU5-1", "uniprot_id": [ { "id": "RYA_DROME", "url": "https://www.uniprot.org/uniprot/G5CKU5", "type": "external" } ], "mass": 13167.0, "length": 109, "protein_name": "RYamide neuropeptides", "gene_name": "RYa", "organism": "Fruit fly", "refseq_name": "RYamide", "refseq_ac": [ { "id": "NP_001104382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104382", "type": "external" } ], "gene_names_uniprotkb": "RYa; CG40733; NepYr", "gene_names_refseq": "CG40733; Dmel\\CG40733; RYa; dRYamide", "protein_names_uniprotkb": "RYamide neuropeptides; Neuropeptide Y-like receptor ligand", "protein_names_refseq": "CG40733-PC; RYa-PC; RYamide", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG40733)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;21704020;21843505", "class_list": "", "function": "Neuropeptides RYamide-1 and RYamide-2 are ligands for the G protein-coupled receptor RYa-R (PubMed:21704020, PubMed:21843505). May suppress feeding behavior (PubMed:21704020)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8Y508;V9I0I4", "ec_number_list": [], "go_molecular_function": "GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:2000252 negative regulation of feeding behavior;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "G5CKU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P19538-1", "uniprot_id": [ { "id": "CI_DROME", "url": "https://www.uniprot.org/uniprot/P19538", "type": "external" } ], "mass": 153280.0, "length": 1397, "protein_name": "Transcriptional activator cubitus interruptus", "gene_name": "ci", "organism": "Fruit fly", "refseq_name": "cubitus interruptus, isoform A", "refseq_ac": [ { "id": "NP_524617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524617", "type": "external" } ], "gene_names_uniprotkb": "ci; CG2125; CID; CI; Ce; Ci155; CiD; Ci[D]; Ci; Dmel\\CG2125; Dmel_CG2125; GLI; Gli; Siah; ci-D; ci155; ciA; ciD; ciR; ci[D]; d Ci; l(4)102ABc; l(4)13; l(4)17", "gene_names_refseq": "CG2125; CID; CI; Ce; Ci/GLI; Ci/Gli; Ci155; CiD; Ci[D]; Ci; Dmel\\CG2125; Gli; Siah; ci-D; ci155; ciA; ciD; ciR; ci[D]; ci; d Ci; l(4)102ABc; l(4)13; l(4)17", "protein_names_uniprotkb": "Transcriptional activator cubitus interruptus; Transcriptional activator ci; ci C-terminally truncated form; ci form of 155 kDa; ci form of 75 kDa; ci full-length protein; ci-155; ci-75; ciFL", "protein_names_refseq": "CG2125-PA; cell; ci-PA; cubitis interruptus; cubitus interruptus, isoform A; cubitus interruptus; cubitus interuptus; cubitus-interruptus-Dominant; cubitus", "tax_id": 7227, "disease": "primary bacterial infectious disease (Disease Ontology:DOID:0050338); pre-malignant neoplasm (Disease Ontology:DOID:0060071); preaxial polydactyly type IV (Disease Ontology:DOID:0060985); preaxial polydactyly I (Disease Ontology:DOID:0060987); spina bifida (Disease Ontology:DOID:0080016); esophageal atresia/tracheoesophageal fistula (Disease Ontology:DOID:0080171); Culler-Jones syndrome (Disease Ontology:DOID:0080328); holoprosencephaly 9 (Disease Ontology:DOID:0110873); hypospadias (Disease Ontology:DOID:10892); syndactyly (Disease Ontology:DOID:11193); polydactyly (Disease Ontology:DOID:1148); clubfoot (Disease Ontology:DOID:11836); biliary atresia (Disease Ontology:DOID:13608); anodontia (Disease Ontology:DOID:13714); Greig cephalopolysyndactyly syndrome (Disease Ontology:DOID:14761); multiple sclerosis (Disease Ontology:DOID:2377); nevoid basal cell carcinoma syndrome (Disease Ontology:DOID:2512); gallbladder cancer (Disease Ontology:DOID:3121); liver cirrhosis (Disease Ontology:DOID:5082); gastric papillary adenocarcinoma (Disease Ontology:DOID:5593); gastric tubular adenocarcinoma (Disease Ontology:DOID:6595); Pallister-Hall syndrome (Disease Ontology:DOID:9248); colorectal cancer (Disease Ontology:DOID:9256); ocular hypertension (Disease Ontology:DOID:9282)", "pathway": " (dme:Dmel_CG2125); (R-DME-209159); (R-DME-209190); (R-DME-209214); (R-DME-209338); (R-DME-209360); (R-DME-209446); (R-DME-216119); (R-DME-216167); (R-DME-216217); (R-DME-5610780); (R-DME-5610785); (R-DME-5610787); (R-DME-5632684)", "pathway_count": 14, "publication_count": 77, "publication_id_list": "10102270;10409506;10458606;10477300;10529426;10557210;10731132;10825151;10862738;10862750;10952898;10966113;11090136;11495917;11778050;11912487;11914126;11934882;11955435;11997517;12231619;12537568;12537572;12537573;12537574;12663920;14523402;14597665;14614827;14636583;15063184;15300262;15331761;15563523;15592457;15598741;15616566;15691767;15750186;15875013;16041759;16110336;16299518;16326393;16386907;16630821;16651542;16740475;1686006;17077139;17102630;17182028;17569856;17569867;17671093;17881487;17925225;17960137;18211840;2166702;25589440;25639794;26109356;26109357;7600980;8769644;8898207;8906787;8906794;9109493;9122207;9215627;9244298;9332387;9431812;9482888;9601642", "class_list": "", "function": "Has a dual function as a transcriptional activator and a repressor of the hedgehog (Hh) pathway. The full-length ci form (ciFL), acts as an activator (ciA) while ciR, its C-terminally truncated form, acts as a repressor. Involved in segment polarity. Required for the normal development of the posterior half of each embryonic segment. Engrailed protein directly represses ci expression in posterior compartment cells. Essential component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required to activate Cad99C-dependent endosome formation, norpA-dependent Ca2+ mobilization and p38 MAPK, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18525;Q8T6T1;Q9V4A8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex;GO:0035301 Hedgehog signaling complex", "go_biological_process": "GO:0030858 positive regulation of epithelial cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 7.8, "record_id": "P19538-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41092-1", "uniprot_id": [ { "id": "RL27A_DROME", "url": "https://www.uniprot.org/uniprot/P41092", "type": "external" } ], "mass": 17022.0, "length": 149, "protein_name": "Large ribosomal subunit protein uL15", "gene_name": "RpL27A", "organism": "Fruit fly", "refseq_name": "ribosomal protein L27A, isoform C", "refseq_ac": [ { "id": "NP_001188689", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188689", "type": "external" } ], "gene_names_uniprotkb": "RpL27A; CG15442; Dmel\\CG15442; Dmel_CG15442; L15; M(2)24F-1; M(2)24F; M(2)Z; M(2)z; M(2L)z; M[[z]]; Mz; M; Rp L27A; RpL27Aa; RpL27Ab; RpL27a2; RpL27a; anon-EST:Posey257; l(2)24EFh; l(2)24Fb; l(2)SH0840; l(2)SH2 0840; rpL27a", "gene_names_refseq": "CG15442; Dmel\\CG15442; L15; M(2)24F-1; M(2)24F; M(2)Z; M(2)z; M(2L)z; M[[z]]; Mz; M; Rp L27A; RpL27Aa; RpL27Ab; RpL27A; RpL27a2; RpL27a; anon-EST:Posey257; l(2)24EFh; l(2)24Fb; l(2)SH0840; l(2)SH2 0840; rpL27a", "protein_names_uniprotkb": "Large ribosomal subunit protein uL15; 60S ribosomal protein L27a", "protein_names_refseq": "CG15442-PC; RpL27A-PC; lethal (2) SH0840; minute (2) 24F; minute; ribosomal protein L27A, isoform C; ribosomal protein L27a", "tax_id": 7227, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (dme:Dmel_CG15442); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;8297386;9055824", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q94530;Q9VR02", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P41092-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08645-1", "uniprot_id": [ { "id": "RAP1_DROME", "url": "https://www.uniprot.org/uniprot/P08645", "type": "external" } ], "mass": 20863.0, "length": 184, "protein_name": "Ras-related protein Rap1", "gene_name": "Rap1", "organism": "Fruit fly", "refseq_name": "Rap1 GTPase, isoform B", "refseq_ac": [ { "id": "NP_001189023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189023", "type": "external" } ], "gene_names_uniprotkb": "Rap1; BEST:GH18528; C-ras3; CG1956; D-Rap1; DRap1; DRap; Dmel\\CG1956; Dmel_CG1956; Dras3; Dras62B; E(faf); EC3-7; FCG-C; P08645; RAP1; RAP; Rap; Ras3; RasIII; R; l(3)62Bf; l(3)R; rap1; ras 3; ras3", "gene_names_refseq": "BEST:GH18528; C-ras3; CG1956; D-Rap1; DRap1; DRap; Dmel\\CG1956; Dras3; Dras62B; E(faf); EC3-7; FCG-C; P08645; RAP1; Rap1; Rap; Ras3; RasIII; R; l(3)62Bf; l(3)R; rap1; ras 3; ras3", "protein_names_uniprotkb": "Ras-related protein Rap1; 3.6.5.2; Rap1 GTPase; Ras-like protein 3", "protein_names_refseq": "CG1956-PB; Rap1 GTPase, isoform B; Rap1-PB; enhancer of faf; roughened", "tax_id": 7227, "disease": "thrombocytopenia (Disease Ontology:DOID:1588)", "pathway": " (dme:Dmel_CG1956); (R-DME-170968); (R-DME-354192); (R-DME-381676); (R-DME-392517); (R-DME-6798695)", "pathway_count": 6, "publication_count": 16, "publication_id_list": "10552039;10731132;12537568;12537569;12537572;12537573;12537574;16110336;16120803;17569856;17569867;1934069;25589440;26109356;26109357;3926484", "class_list": "", "function": "Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in photoreceptor cell determination., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2XYB6;Q540V3;Q9V3N0", "ec_number_list": [ { "id": "1.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.-", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" }, { "id": "3.4.16.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.16.2", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "3.2.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.25", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.3.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.78", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031252 cell leading edge;GO:0016020 membrane", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:2000301 negative regulation of synaptic vesicle exocytosis;GO:0045880 positive regulation of smoothened signaling pathway;GO:0032486 Rap protein signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P08645-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P00528-1", "uniprot_id": [ { "id": "SRC64_DROME", "url": "https://www.uniprot.org/uniprot/P00528", "type": "external" } ], "mass": 63003.0, "length": 552, "protein_name": "Tyrosine-protein kinase Src64B", "gene_name": "Src64B", "organism": "Fruit fly", "refseq_name": "Src oncogene at 64B, isoform D", "refseq_ac": [ { "id": "NP_001014561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014561", "type": "external" } ], "gene_names_uniprotkb": "Src64B; C-src1; CG7524; D-Src64B; D-src; DSRC64; DSrc64B; DSrc64; DSrc; Dm SRC1; DmHD-358; Dmel\\CG7524; Dmel_CG7524; Dsrc64B; Dsrc64; Dsrc; HD-358; MRE5; SRC 64B; SRC64B; SRC; Src1; Src64b; Src64; Src; c-Src; c-src; dSrc64B; dSrc; dsrc; pSrc; src1; src64B; src64b; src64; src", "gene_names_refseq": "C-src1; CG7524; D-Src64B; D-src; DSRC64; DSrc64B; DSrc64; DSrc; Dm SRC1; DmHD-358; Dmel\\CG7524; Dsrc64B; Dsrc64; Dsrc; HD-358; MRE5; SRC 64B; SRC64B; SRC; Src1; Src64B; Src64b; Src64; Src; c-Src; c-src; dSrc64B; dSrc; dsrc; pSrc; src1; src64B; src64b; src64; src", "protein_names_uniprotkb": "Tyrosine-protein kinase Src64B; 2.7.10.2; Dsrc64", "protein_names_refseq": "CG7524-PD; Src oncogene at 64B, isoform D; Src proto oncogene sequence; Src64B-PD; mRNA-like ncRNA in embryogenesis 5", "tax_id": 7227, "disease": "immunodeficiency 22 (Disease Ontology:DOID:0111937); intestinal cancer (Disease Ontology:DOID:10155); allergic conjunctivitis (Disease Ontology:DOID:11204); cancer (Disease Ontology:DOID:162); Goldenhar syndrome (Disease Ontology:DOID:2907); carcinoma (Disease Ontology:DOID:305); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); kidney disease (Disease Ontology:DOID:557); retinal degeneration (Disease Ontology:DOID:8466); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG7524)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;12014990;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;2996778;31491385;6317185;9731193", "class_list": "", "function": "Tyrosine-protein kinase that may play a role in the development of neural tissue and smooth muscle (PubMed:2996778). May contribute to tyrosine phosphorylation of Dscam1, a cell surface receptor involved in targeting of growing axons during eye morphogenesis (PubMed:12014990)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1H7;O18372;Q9VZA2", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005102 signaling receptor binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005917 nephrocyte diaphragm;GO:0045172 germline ring canal", "go_biological_process": "GO:0030046 parallel actin filament bundle assembly;GO:0008064 regulation of actin polymerization or depolymerization;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0030154 cell differentiation;GO:0048167 regulation of synaptic plasticity", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P00528-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21750-1", "uniprot_id": [ { "id": "SALA_DROME", "url": "https://www.uniprot.org/uniprot/P21750", "type": "external" } ], "mass": 14555.0, "length": 142, "protein_name": "Protein spalt-accessory", "gene_name": "sala", "organism": "Fruit fly", "refseq_name": "spalt-adjacent, isoform C", "refseq_ac": [ { "id": "NP_001245985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245985", "type": "external" } ], "gene_names_uniprotkb": "sala; BcDNA:RE40068; CG4922; Dmel\\CG4922; Dmel_CG4922; Sala; Sal; chr2L:11486634..11486740; nsal; sal", "gene_names_refseq": "BcDNA:RE40068; CG4922; Dmel\\CG4922; Sala; Sal; chr2L:11486634..11486740; nsal; sala; sal", "protein_names_uniprotkb": "Protein spalt-accessory; Protein spalt-adjacent", "protein_names_refseq": "CG4922-PC; not-spalt; sal adjacent; sala-PC; spalt accessory; spalt-adjacent, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4922)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;16453821;17569856;17569867;25589440;2568636;26109356;26109357;8601339", "class_list": "", "function": "Likely to be involved in the establishment of the head., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VKH1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007369 gastrulation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P21750-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P07207-1", "uniprot_id": [ { "id": "NOTCH_DROME", "url": "https://www.uniprot.org/uniprot/P07207", "type": "external" } ], "mass": 288853.0, "length": 2703, "protein_name": "Neurogenic locus Notch protein", "gene_name": "N", "organism": "Fruit fly", "refseq_name": "notch, isoform B", "refseq_ac": [ { "id": "NP_001245510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245510", "type": "external" } ], "gene_names_uniprotkb": "N; 1.1; 16-178; 16-55; Ax; CG3936; CT13012; Chp; Co; Dmel\\CG3936; Dmel_CG3936; EG:140G11.1; EG:163A10.2; NECD; NICD; Nicd; RICN; anon-EST:Liang-1.12; clone 1.12; co; dNotch; fa; l(1)3Cb; l(1)Ax; l(1)N; n[fah]; nd; notch; shd; spl; swb", "gene_names_refseq": "1.1; 16-178; 16-55; Ax; CG3936; CT13012; Chp; Co; Dmel\\CG3936; EG:140G11.1; EG:163A10.2; NECD; NICD; Nicd; N; RICN; anon-EST:Liang-1.12; clone 1.12; co; dNotch; fa; l(1)3Cb; l(1)Ax; l(1)N; n[fah]; nd; notch; shd; spl; swb", "protein_names_uniprotkb": "Neurogenic locus Notch protein", "protein_names_refseq": "CG3936-PB; N-PB; NICD; abruptex; chopped; confluens; dNotch; facet; notch, isoform B; notchoid; split; strawberry", "tax_id": 7227, "disease": "adult T-cell leukemia/lymphoma (Disease Ontology:DOID:0050523); Adams-Oliver syndrome (Disease Ontology:DOID:0060227); autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 (Disease Ontology:DOID:0061227); familial partial lipodystrophy type 1 (Disease Ontology:DOID:0070207); infantile myofibromatosis 2 (Disease Ontology:DOID:0070667); aortic valve disease 1 (Disease Ontology:DOID:0080333); autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 (Disease Ontology:DOID:0111035); lateral meningocele syndrome (Disease Ontology:DOID:0111343); intestinal cancer (Disease Ontology:DOID:10155); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); neurodegenerative disease (Disease Ontology:DOID:1289); retinopathy of prematurity (Disease Ontology:DOID:13025); brain cancer (Disease Ontology:DOID:1319); endometrial cancer (Disease Ontology:DOID:1380); alcohol use disorder (Disease Ontology:DOID:1574); cancer (Disease Ontology:DOID:162); congenital heart disease (Disease Ontology:DOID:1682); transient cerebral ischemia (Disease Ontology:DOID:224); hemangiopericytoma (Disease Ontology:DOID:264); Hajdu-Cheney syndrome (Disease Ontology:DOID:2736); adenocarcinoma (Disease Ontology:DOID:299); central nervous system cancer (Disease Ontology:DOID:3620); pulmonary fibrosis (Disease Ontology:DOID:3770); lung adenocarcinoma (Disease Ontology:DOID:3910); lung large cell carcinoma (Disease Ontology:DOID:4556); cholangiocarcinoma (Disease Ontology:DOID:4947); lung small cell carcinoma (Disease Ontology:DOID:5409); Alagille syndrome (Disease Ontology:DOID:9245); colorectal cancer (Disease Ontology:DOID:9256); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG3936)", "pathway_count": 1, "publication_count": 56, "publication_id_list": "10206646;10206647;10731132;10731137;10935637;11719214;11799064;12369105;12537568;12537572;12537573;12537574;12909620;14573873;15620649;15620650;15692013;16110336;17084357;17084358;17088062;17329366;17569856;17569867;18194540;18243100;18327897;18342578;18948267;20152183;21262215;22158438;22162134;23056424;23178945;23671640;24554766;25589440;25804739;26109356;26109357;27151950;27268051;2780284;28899667;29309414;2981631;30018219;3037327;3097517;33349255;38359610;3935325;7671825;8162848;9012507", "class_list": "", "function": "Essential signaling protein which has a major role in many developmental processes (PubMed:3935325). Functions as a receptor for membrane-bound ligands Delta and Serrate to regulate cell-fate determination (PubMed:10935637, PubMed:12909620, PubMed:15620650, PubMed:18243100). Upon ligand activation, and releasing from the cell membrane, the Notch intracellular domain (NICD) forms a transcriptional activator complex with Su(H) (Suppressor of hairless) and activates genes of the E(spl) complex (PubMed:7671825). Regulates oogenesis, the differentiation of the ectoderm and the development of the central and peripheral nervous system, eye, wing disk, muscles and segmental appendages such as antennae and legs, through lateral inhibition or induction (PubMed:11719214, PubMed:12369105, PubMed:3935325). Regulates neuroblast self-renewal, identity and proliferation through the regulation of bHLH-O proteins; in larval brains, involved in the maintenance of type II neuroblast self-renewal and identity by suppressing erm expression together with pnt; might also regulate dpn expression through the activation of the transcriptional regulator Su(H) (PubMed:18342578, PubMed:20152183, PubMed:21262215, PubMed:23056424, PubMed:27151950, PubMed:28899667). Targeted for ESCRT-mediated endosomal sequestration and lysosomal degradation by various E3 ubiquitin ligases to regulate the Notch signaling pathway (PubMed:17084358, PubMed:22162134, PubMed:33349255). Can undergo ligand-dependent and non-canonical ligand-independent activation (PubMed:22162134). Ligand-independent activation is dependent on endosome acidification and probably occurs in late endosomes or lysosome (PubMed:23178945). Ectopic ligand-independent activation occurs when disruption of the endolysosomal pathway, particularly of the ESCRT-III complex, prevents sequestration of the receptor in intraluminal vesicles of multivesicular bodies (PubMed:17084357, PubMed:17084358, PubMed:17088062, PubMed:23178945)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 12, "predicted_n_glycosites": 11, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 44, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 18, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 57, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 57, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 33, "glyco_site_count": 69, "binding_glycan_count": 0, "secondary_ac_list": "O97458;P04154;Q9W4T8", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0004888 transmembrane signaling receptor activity;GO:0005509 calcium ion binding;GO:0050699 WW domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005769 early endosome", "go_biological_process": "GO:0046331 lateral inhibition;GO:0048749 compound eye development;GO:0035162 embryonic hemopoiesis;GO:0006110 regulation of glycolytic process;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 11.5, "record_id": "P07207-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000100000000000.0100000011001.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25843-1", "uniprot_id": [ { "id": "PROF_DROME", "url": "https://www.uniprot.org/uniprot/P25843", "type": "external" } ], "mass": 13723.0, "length": 126, "protein_name": "Profilin", "gene_name": "chic", "organism": "Fruit fly", "refseq_name": "chickadee, isoform E", "refseq_ac": [ { "id": "NP_001245905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245905", "type": "external" } ], "gene_names_uniprotkb": "chic; 7; CG9553; ChicE1; Chic; Chi; D88; Dmel\\CG9553; Dmel_CG9553; GH4; chi; profilin; prof; sand", "gene_names_refseq": "CG9553; ChicE1; Chic; Chi; D88; Dmel\\CG9553; GH4; chic; chi; l(2)27/7; profilin; prof; sand", "protein_names_uniprotkb": "Profilin; Protein chickadee", "protein_names_refseq": "CG9553-PE; DProfilin; chic-PE; chicadee; chickaddee; chickadee, isoform E; chickadee; profilin; stranded", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); myopathy (Disease Ontology:DOID:423)", "pathway": " (dme:Dmel_CG9553)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1339308;15917496;16110336;17569856;17569867;25589440;26109356;26109357;37041188", "class_list": "", "function": "Binds to actin and affects the structure of the cytoskeleton (PubMed:1339308). At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (PubMed:1339308). By binding to PIP2, it may inhibit the formation of IP3 and DG (PubMed:1339308). This profilin is required for intercellular cytoplasm transport during Drosophila oogenesis (PubMed:1339308). Function in neurons is essential for adult survival, and is important for climbing behavior and activity (PubMed:37041188)., [UniProtKB, PubMed, PubMed]; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3YMV6;Q9VMJ9", "ec_number_list": [], "go_molecular_function": "GO:0003785 actin monomer binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005938 cell cortex;GO:0048471 perinuclear region of cytoplasm;GO:0043005 neuron projection", "go_biological_process": "GO:0032507 maintenance of protein location in cell;GO:0048680 positive regulation of axon regeneration;GO:0007015 actin filament organization;GO:0016322 neuron remodeling;GO:0000902 cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P25843-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40793-1", "uniprot_id": [ { "id": "CDC42_DROME", "url": "https://www.uniprot.org/uniprot/P40793", "type": "external" } ], "mass": 21403.0, "length": 191, "protein_name": "Cdc42 homolog", "gene_name": "Cdc42", "organism": "Fruit fly", "refseq_name": "cell division cycle 42, isoform C", "refseq_ac": [ { "id": "NP_001245762", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245762", "type": "external" } ], "gene_names_uniprotkb": "Cdc42; CDC-42; CDC42; CG12530; Cdc 42; Cdc-42; Cdc42Dm; D-CDC42; D-Cdc42; D-cdc42; DCDC42; DCdc42; Dcdc42; Dm Cdc42; DmCDC42; Dmcdc42; Dmel\\CG12530; Dmel_CG12530; P40793; cdc42", "gene_names_refseq": "CDC-42; CDC42; CG12530; Cdc 42; Cdc-42; Cdc42Dm; Cdc42; D-CDC42; D-Cdc42; D-cdc42; DCDC42; DCdc42; Dcdc42; Dm Cdc42; DmCDC42; Dmcdc42; Dmel\\CG12530; P40793; cdc42", "protein_names_uniprotkb": "Cdc42 homolog; 3.6.5.2", "protein_names_refseq": "CG12530-PC; Cdc42-PC; Cdc42-like; cell division cycle 42, isoform C", "tax_id": 7227, "disease": "cerebral cavernous malformation (Disease Ontology:DOID:0060669); microvillus inclusion disease (Disease Ontology:DOID:0060775); Alzheimer's disease (Disease Ontology:DOID:10652); pancreatic cancer (Disease Ontology:DOID:1793); syndrome (Disease Ontology:DOID:225); bipolar disorder (Disease Ontology:DOID:3312); temporal lobe epilepsy (Disease Ontology:DOID:3328); fibrosarcoma (Disease Ontology:DOID:3355); rhinitis (Disease Ontology:DOID:4483); myelofibrosis (Disease Ontology:DOID:4971); kidney disease (Disease Ontology:DOID:557); cleft palate (Disease Ontology:DOID:674)", "pathway": " (dme:Dmel_CG12530); (R-DME-114604); (R-DME-182971); (R-DME-2029482); (R-DME-389359); (R-DME-3928662); (R-DME-525793); (R-DME-5627123); (R-DME-5663213); (R-DME-5663220); (R-DME-5687128); (R-DME-8964616); (R-DME-9013148); (R-DME-9013149); (R-DME-9013406); (R-DME-9013409); (R-DME-9013420); (R-DME-9013423); (R-DME-9013424); (R-DME-983231); (R-DME-9958810); (R-DME-9958825)", "pathway_count": 22, "publication_count": 18, "publication_id_list": "10731132;10772800;12490550;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;26801180;7958857;8628256;9371783", "class_list": "", "function": "Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions (PubMed:12490550). Together with mbt and Frl, regulates photoreceptor cell morphogenesis (PubMed:12490550, PubMed:26801180). Together with Frl, has a role in the neuronal development of mushroom bodies (PubMed:26801180)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q540W4;Q9U9S3;Q9U9S4;Q9U9S5;Q9U9S6;Q9V465", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0032794 GTPase activating protein binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005938 cell cortex", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0051601 exocyst localization;GO:0050975 sensory perception of touch;GO:0006897 endocytosis;GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P40793-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41073-1", "uniprot_id": [ { "id": "PEP_DROME", "url": "https://www.uniprot.org/uniprot/P41073", "type": "external" } ], "mass": 78048.0, "length": 716, "protein_name": "Zinc finger protein on ecdysone puffs", "gene_name": "Pep", "organism": "Fruit fly", "refseq_name": "protein on ecdysone puffs, isoform D", "refseq_ac": [ { "id": "NP_001246817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246817", "type": "external" } ], "gene_names_uniprotkb": "Pep; CG6143; Dmel\\CG6143; Dmel_CG6143; PEP; X4; p100; pep", "gene_names_refseq": "CG6143; Dmel\\CG6143; PEP/X4; PEP; Pep; X4/PEP; p100; pep", "protein_names_uniprotkb": "Zinc finger protein on ecdysone puffs", "protein_names_refseq": "74F gene; CG6143-PD; Pep-PD; protein on ecdysone puffs, isoform D", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG6143)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;1899840;25589440;26109356;26109357", "class_list": "", "function": "May play a role in the process of early and late gene activation, or possibly in RNA processing, for a defined set of developmentally regulated loci., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8IGB1;Q8MSV5;Q9VVJ2;Q9VVJ3;Q9VVJ4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003727 single-stranded RNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0048024 regulation of mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P41073-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22814-1", "uniprot_id": [ { "id": "RUNT_DROME", "url": "https://www.uniprot.org/uniprot/P22814", "type": "external" } ], "mass": 53209.0, "length": 510, "protein_name": "Segmentation protein Runt", "gene_name": "run", "organism": "Fruit fly", "refseq_name": "runt, isoform C", "refseq_ac": [ { "id": "NP_001285501", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285501", "type": "external" } ], "gene_names_uniprotkb": "run; 13.1; 1; 2; AA33; CG1849; Dmel\\CG1849; Dmel_CG1849; LB5; P235; RUN; Rnt; Runt; Run; l(1)19Ea; l(1)AA33; l(1)LB9; lLB5; leg; runt", "gene_names_refseq": "1; 2; AA33; CG1849; Dmel\\CG1849; LB5; P235; RUN; Rnt; Runt; Run; l(1)19Ea; l(1)AA33; l(1)B2/13.1; l(1)LB9; lLB5; leg; runt; run", "protein_names_uniprotkb": "Segmentation protein Runt", "protein_names_refseq": "CG1849-PC; legless; run-PC; runt, isoform C; runt; section 1; section 2", "tax_id": 7227, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); inflammatory bowel disease (Disease Ontology:DOID:0050589); developmental disorder of mental health (Disease Ontology:DOID:0060037); idiopathic scoliosis (Disease Ontology:DOID:0060250); metaphyseal dysplasia-maxillary hypoplasia-brachydactyly syndrome (Disease Ontology:DOID:0111513); osteonecrosis (Disease Ontology:DOID:10159); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); cleidocranial dysplasia (Disease Ontology:DOID:13994); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovary epithelial cancer (Disease Ontology:DOID:2152); ovarian cancer (Disease Ontology:DOID:2394); asthma (Disease Ontology:DOID:2841); endometrial carcinoma (Disease Ontology:DOID:2871); endometriosis (Disease Ontology:DOID:289); invasive ductal carcinoma (Disease Ontology:DOID:3008); middle cerebral artery infarction (Disease Ontology:DOID:3525); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); papillary thyroid carcinoma (Disease Ontology:DOID:3969); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (dme:Dmel_CG1849); (R-DME-549127); (R-DME-8877330); (R-DME-8878166); (R-DME-8931987); (R-DME-8934593); (R-DME-8936459); (R-DME-8939236); (R-DME-8939243); (R-DME-8939245); (R-DME-8939246); (R-DME-8939247); (R-DME-8939902); (R-DME-8940973); (R-DME-8941326); (R-DME-8941855); (R-DME-8941858); (R-DME-8951430); (R-DME-8951671); (R-DME-8951936); (R-DME-9018519)", "pathway_count": 21, "publication_count": 15, "publication_id_list": "10368951;10731132;12537568;12537572;12537573;12537574;15014160;1560822;16110336;17569856;17569867;2249771;25589440;26109356;26109357", "class_list": "", "function": "Plays a pivotal role in regulating the expression of other pair-rule genes such as eve, ftz, and h., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AVT9;O76551;Q6SD78;Q7KPD6;Q8MRF4;Q9TVG1;Q9TVZ7;Q9TZQ9;Q9TZR0;Q9VRB6", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0005524 ATP binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P22814-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P31009-1", "uniprot_id": [ { "id": "RS2_DROME", "url": "https://www.uniprot.org/uniprot/P31009", "type": "external" } ], "mass": 28900.0, "length": 267, "protein_name": "Small ribosomal subunit protein uS5", "gene_name": "RpS2", "organism": "Fruit fly", "refseq_name": "ribosomal protein S2, isoform B", "refseq_ac": [ { "id": "NP_001260303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260303", "type": "external" } ], "gene_names_uniprotkb": "RpS2; CG5920; Dm01335; Dmel\\CG5920; Dmel_CG5920; Rp S2; S2; S5; anon-EST:Posey202; dS2; l(2)03848; l(2)k04603; rpS2; rps2; sop", "gene_names_refseq": "CG5920; Dm01335; Dmel\\CG5920; Rp S2; RpS2; S2; S5; anon-EST:Posey202; dS2; l(2)03848; l(2)k04603; rpS2; rps2; sop", "protein_names_uniprotkb": "Small ribosomal subunit protein uS5; 40S ribosomal protein S2; Protein strings of pearls", "protein_names_refseq": "40S ribosomal protein S2; CG5920-PB; RpS2-PB; S2 ribosomal protein; ribosomal protein S2, isoform B; ribosome RS2; string of pearls", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5920); (R-DME-156827); (R-DME-1799339); (R-DME-3214858); (R-DME-6791226); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-8876725); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 15, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;23636399;25589440;26109356;26109357;7982558;8441641", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). Has a specific developmental role during oogenesis (PubMed:7982558)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VL74", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit;GO:0015935 small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0048477 oogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P31009-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40792-1", "uniprot_id": [ { "id": "RAC1_DROME", "url": "https://www.uniprot.org/uniprot/P40792", "type": "external" } ], "mass": 21354.0, "length": 192, "protein_name": "Ras-related protein Rac1", "gene_name": "Rac1", "organism": "Fruit fly", "refseq_name": "Rac1, isoform B", "refseq_ac": [ { "id": "NP_001261247", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261247", "type": "external" } ], "gene_names_uniprotkb": "Rac1; 2248; CED-10; CG2248; D-Rac 1; D-Rac1; D-Rac; DRac1; DRacA; DRac; Dm Rac1; DmRAC1; DmRAC; Dmel\\CG2248; Dmel_CG2248; Dmrac1; Drac1a; Drac1; DracA; Drac; GTPase Rac1; P40792; RAC1; Rac GTPase; Rac-1; Rac-GTP; Rac3; RacA; Rac; dRac1; dRac; drac1; rac-1; rac1; rac", "gene_names_refseq": "2248; CED-10; CG2248; D-Rac 1; D-Rac1; D-Rac; DRac1; DRacA; DRac; Dm Rac1; DmRAC1; DmRAC; Dmel\\CG2248; Dmrac1; Drac1a; Drac1; DracA; Drac; GTPase Rac1; P40792; RAC1; Rac GTPase; Rac-1; Rac-GTP; Rac1; Rac3; RacA; Rac; dRac1; dRac; drac1; rac-1; rac1; rac", "protein_names_uniprotkb": "Ras-related protein Rac1; 3.6.5.2", "protein_names_refseq": "CG2248-PB; Rac GTPase; Rac1, isoform B; Rac1-PB", "tax_id": 7227, "disease": "colon adenoma (Disease Ontology:DOID:0050912); colorectal carcinoma (Disease Ontology:DOID:0080199); autosomal dominant intellectual developmental disorder 48 (Disease Ontology:DOID:0080235); immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia (Disease Ontology:DOID:0112061); immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia (Disease Ontology:DOID:0112062); immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis (Disease Ontology:DOID:0112064); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); epilepsy (Disease Ontology:DOID:1826); colon adenocarcinoma (Disease Ontology:DOID:234); extrahepatic bile duct adenocarcinoma (Disease Ontology:DOID:3495); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); gastric adenocarcinoma (Disease Ontology:DOID:3717); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); gallbladder carcinoma (Disease Ontology:DOID:4948); kidney disease (Disease Ontology:DOID:557); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (dme:Dmel_CG2248); (R-DME-114604); (R-DME-1433557); (R-DME-193648); (R-DME-2029482); (R-DME-2424491); (R-DME-2871796); (R-DME-350376); (R-DME-389359); (R-DME-3928662); (R-DME-3928664); (R-DME-3928665); (R-DME-4086400); (R-DME-4420097); (R-DME-445144); (R-DME-5218920); (R-DME-5625740); (R-DME-5625900); (R-DME-5627123); (R-DME-5663213); (R-DME-5687128); (R-DME-6798695); (R-DME-8849471); (R-DME-9013149); (R-DME-9013423); (R-DME-9748787); (R-DME-983231); (R-DME-9958810); (R-DME-9958825)", "pathway_count": 29, "publication_count": 23, "publication_id_list": "10323867;10469646;10731132;12537568;12537569;12537572;12537573;12537574;12818175;16110336;17507675;17569856;17569867;22547074;24855950;25589440;26109356;26109357;7720592;7835340;7958857;8628256;9694801", "class_list": "", "function": "During various developmental processes, regulates changes in cell morphology in response to extracellular signals (PubMed:10323867, PubMed:24855950, PubMed:7958857). During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE-cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion between the leader border cells and nurse cells further promotes Rac1 signaling creating a positive feedback loop that amplifies the output of RTK activity and leads to higher Rac activity at the front, thus promoting polarization of the border cell cluster and directionally persistent migration (PubMed:24855950). Involved in axon outgrowth and myoblast fusion (PubMed:7958857). Plays a role in regulating dorsal closure during embryogenesis (PubMed:10323867). Involved in integrin alpha-PS3/beta-nu-mediated phagocytosis of Gram-positive S.aureus by hemocytes (PubMed:22547074)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W0H7", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.-", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.4.16.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.16.2", "type": "external" }, { "id": "5.6.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.3", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "3.4.24.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.11", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity;GO:0032794 GTPase activating protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:1904059 regulation of locomotor rhythm;GO:0050770 regulation of axonogenesis;GO:0050975 sensory perception of touch;GO:0006911 phagocytosis, engulfment;GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P40792-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P13395-1", "uniprot_id": [ { "id": "SPTCA_DROME", "url": "https://www.uniprot.org/uniprot/P13395", "type": "external" } ], "mass": 278303.0, "length": 2415, "protein_name": "Spectrin alpha chain", "gene_name": "alpha-Spec", "organism": "Fruit fly", "refseq_name": "alpha spectrin, isoform A", "refseq_ac": [ { "id": "NP_476739", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476739", "type": "external" } ], "gene_names_uniprotkb": "alpha-Spec; 3A9; AlphaSpec; CG1977; Dmel\\CG1977; Dmel_CG1977; FBtr0072789; FCP-B; SPEC-A; SPTCA; Spectrin; Spec; Sp; alfa-Spec; alpha pectrin; alpha spectrin; alpha-SPEC; alpha-Spc; alpha-Spectrin; alpha-Spect; alpha-Spe; alpha-Sp; alpha-spectrin; alpha-spec; alphaSpectrin; alphaSpec; alphaSp; alpha; anon-EST:fe2E2; dre3; klo; l(3)04276; l(3)62Bd; l(3)alpha-Spec; l(3)dre3; spectrin", "gene_names_refseq": "3A9; AlphaSpec; CG1977; Dmel\\CG1977; FBtr0072789; FCP-B; SPTCA; Spectrin; Spec; Sp; alfa-Spec; alpha pectrin; alpha spectrin; alpha-SPEC; alpha-Spc; alpha-Spectrin; alpha-Spect; alpha-Spec; alpha-Spe; alpha-Sp; alpha-spectrin; alpha-spec; alphaSpectrin; alphaSpec; alphaSp; alpha; anon-EST:fe2E2; dre3; klo; l(3)04276; l(3)62Bd; l(3)alpha-Spec; l(3)dre3; spectrin", "protein_names_uniprotkb": "Spectrin alpha chain", "protein_names_refseq": "CG1977-PA; aSpc 3A9; alpha spectrin, isoform A; alpha spectrin; alpha-SPECTRIN; alpha-Spec-PA; alpha-spectrin II; alphaSpectrin; anon-fast-evolving-2E2; klotzchen", "tax_id": 7227, "disease": "hereditary pyropoikilocytosis (Disease Ontology:DOID:0061026); hereditary spastic paraplegia 91 (Disease Ontology:DOID:0070643); developmental and epileptic encephalopathy 5 (Disease Ontology:DOID:0080438); autosomal dominant distal hereditary motor neuronopathy 11 (Disease Ontology:DOID:0081400); hereditary spherocytosis type 1 (Disease Ontology:DOID:0110916); hereditary spherocytosis type 3 (Disease Ontology:DOID:0110918); sickle cell anemia (Disease Ontology:DOID:10923); hereditary spherocytosis (Disease Ontology:DOID:12971)", "pathway": " (dme:Dmel_CG1977); (R-DME-264870); (R-DME-375165); (R-DME-445095); (R-DME-5673001); (R-DME-6798695); (R-DME-6807878); (R-DME-9013420); (R-DME-9013424)", "pathway_count": 9, "publication_count": 25, "publication_id_list": "10731132;11076973;12537568;12537569;12537572;12537573;12537574;14667407;16110336;17372656;17569856;17569867;18327897;20237161;22426000;2497103;25589440;26109356;26109357;2808524;3680372;8266097;8276898;9012507;9344535", "class_list": "", "function": "Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi-derived membrane secretion required for the formation of furrows during cellularization., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q26340;Q3KN50;Q8SZW7;Q9W085", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0008017 microtubule binding;GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0016323 basolateral plasma membrane;GO:0030054 cell junction", "go_biological_process": "GO:0048790 maintenance of presynaptic active zone structure;GO:0007009 plasma membrane organization;GO:0007274 neuromuscular synaptic transmission;GO:0016199 axon midline choice point recognition;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P13395-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08570-1", "uniprot_id": [ { "id": "RLA1_DROME", "url": "https://www.uniprot.org/uniprot/P08570", "type": "external" } ], "mass": 11513.0, "length": 112, "protein_name": "Large ribosomal subunit protein P1", "gene_name": "RpLP1", "organism": "Fruit fly", "refseq_name": "ribosomal protein LP1, isoform B", "refseq_ac": [ { "id": "NP_001259822", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259822", "type": "external" } ], "gene_names_uniprotkb": "RpLP1; CG4087; Dmel\\CG4087; Dmel_CG4087; LP1; M(2)21C1-2; M(2)21C; P1; RLA1_DROME; RP21C; RPA2; RpA2; RpLp1; RpP2; Rplp1; chr2L:420593..420726; rp21C; rpA2; rpP2; rpa2", "gene_names_refseq": "CG4087; Dmel\\CG4087; LP1; M(2)21C1-2; M(2)21C; P1; RLA1_DROME; RP21C; RPA2; RpA2; RpLP1; RpLp1; RpP2; Rplp1; chr2L:420593..420726; rp21C; rpA2; rpP2; rpa2", "protein_names_uniprotkb": "Large ribosomal subunit protein P1; 60S acidic ribosomal protein P1; Acidic ribosomal protein RPA2; RP21C", "protein_names_refseq": "ACIDIC RIBOSOMAL PROTEIN LP1; CG4087-PB; Minute(2)21C; Ribosomal-protein-A2; RpLP1-PB; ribosomal protein A2; ribosomal protein LP1, isoform B; ribosomal protein P2", "tax_id": 7227, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (dme:Dmel_CG4087); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;3122177;8501137", "class_list": "", "function": "Plays an important role in the elongation step of protein synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPP6", "ec_number_list": [], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:0030295 protein kinase activator activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P08570-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O18391-1", "uniprot_id": [ { "id": "KRAK_DROME", "url": "https://www.uniprot.org/uniprot/O18391", "type": "external" } ], "mass": 37094.0, "length": 331, "protein_name": "Probable serine hydrolase", "gene_name": "kraken", "organism": "Fruit fly", "refseq_name": "kraken, isoform B", "refseq_ac": [ { "id": "NP_001259847", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259847", "type": "external" } ], "gene_names_uniprotkb": "kraken; CG3943; Dmel\\CG3943; Dmel_CG3943; Kraken; Kra; SERHL2; SERHL", "gene_names_refseq": "CG3943; Dmel\\CG3943; Kraken; Kra; SERHL2; SERHL; kraken", "protein_names_uniprotkb": "Probable serine hydrolase; 3.1.-.-; Kraken protein", "protein_names_refseq": "CG3943-PB; kraken, isoform B; kraken-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3943)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9831651", "class_list": "", "function": "May have a role in detoxification and digestion during embryogenesis and larval development., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0052689 carboxylic ester hydrolase activity;GO:0017171 serine hydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0009636 response to toxic substance;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "O18391-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48554-1", "uniprot_id": [ { "id": "RAC2_DROME", "url": "https://www.uniprot.org/uniprot/P48554", "type": "external" } ], "mass": 21359.0, "length": 192, "protein_name": "Ras-related protein Rac2", "gene_name": "Rac2", "organism": "Fruit fly", "refseq_name": "Rac2, isoform B", "refseq_ac": [ { "id": "NP_001261517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261517", "type": "external" } ], "gene_names_uniprotkb": "Rac2; CG8556; D-Rac 2; D-Rac2; DRac2; DRacB; DmRAC2; Dmel\\CG8556; Dmel_CG8556; Drac1b; Drac2; P48554; RAC1B; Rac GTPase; Rac-2; Rac1b; Rac1; RacB; Rac; Rhog; rac2", "gene_names_refseq": "CG8556; D-Rac 2; D-Rac2; DRac2; DRacB; DmRAC2; Dmel\\CG8556; Drac1b; Drac2; P48554; RAC1B; Rac GTPase; Rac-2; Rac1b; Rac1; Rac2; RacB; Rac; Rhog; rac2", "protein_names_uniprotkb": "Ras-related protein Rac2", "protein_names_refseq": "CG8556-PB; Rac GTPase; Rac2, isoform B; Rac2-PB", "tax_id": 7227, "disease": "colon adenoma (Disease Ontology:DOID:0050912); colorectal carcinoma (Disease Ontology:DOID:0080199); autosomal dominant intellectual developmental disorder 48 (Disease Ontology:DOID:0080235); immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia (Disease Ontology:DOID:0112061); immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia (Disease Ontology:DOID:0112062); immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis (Disease Ontology:DOID:0112064); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); epilepsy (Disease Ontology:DOID:1826); colon adenocarcinoma (Disease Ontology:DOID:234); extrahepatic bile duct adenocarcinoma (Disease Ontology:DOID:3495); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); gastric adenocarcinoma (Disease Ontology:DOID:3717); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); gallbladder carcinoma (Disease Ontology:DOID:4948); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (dme:Dmel_CG8556); (R-DME-4086400); (R-DME-9013423)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10323867;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;22547074;25589440;26109356;26109357;7720592;7835340", "class_list": "", "function": "Involved in integrin alpha-PS3/beta-nu-mediated phagocytosis of Gram-positive S.aureus by hemocytes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q540X5;Q9VS69", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0042995 cell projection", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0006911 phagocytosis, engulfment;GO:0007015 actin filament organization;GO:0007617 mating behavior;GO:0032956 regulation of actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P48554-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17276-1", "uniprot_id": [ { "id": "PH4H_DROME", "url": "https://www.uniprot.org/uniprot/P17276", "type": "external" } ], "mass": 51660.0, "length": 452, "protein_name": "Protein henna", "gene_name": "Hn", "organism": "Fruit fly", "refseq_name": "henna, isoform B", "refseq_ac": [ { "id": "NP_001014573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014573", "type": "external" } ], "gene_names_uniprotkb": "Hn; CG7399; DTPHu; DTPH; Dmel\\CG7399; Dmel_CG7399; PAH; Pah; TPH; TRH; TpH; Tph; Trh; bu; pah", "gene_names_refseq": "CG7399; DTPHu; DTPH; Dmel\\CG7399; Hn; PAH; Pah; TPH; TRH; TpH; Tph; Trh; bu; pah", "protein_names_uniprotkb": "Protein henna; 1.14.16.1; 1.14.16.4; PAH; Phe-4-monooxygenase; Phenylalanine-4-hydroxylase; TRH; Tryptophan 5-hydroxylase; Tryptophan 5-monooxygenase", "protein_names_refseq": "CG7399-PB; Hn-PB; Phenylalanine-hydroxylase; brunette; henna, isoform B; henna; phenylalanine hydroxylase; phenylalanine-tryptophan hydroxylase; tryptophan hydrolase", "tax_id": 7227, "disease": "intellectual disability (Disease Ontology:DOID:1059); phenylketonuria (Disease Ontology:DOID:9281)", "pathway": " (dme:Dmel_CG7399); (R-DME-8964208)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10333570;10731132;12537568;12537569;12537572;12537573;12537574;1371286;16110336;17569856;17569867;2121612;25589440;26109356;26109357;8769124", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O46110;Q27599;Q27600", "ec_number_list": [ { "id": "1.14.16.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.1", "type": "external" }, { "id": "1.14.16.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.4", "type": "external" } ], "go_molecular_function": "GO:0004510 tryptophan 5-monooxygenase activity;GO:0005506 iron ion binding;GO:0004505 phenylalanine 4-monooxygenase activity", "go_cellular_component": "", "go_biological_process": "GO:0006571 tyrosine biosynthetic process;GO:0042416 dopamine biosynthetic process;GO:0006726 eye pigment biosynthetic process;GO:0007616 long-term memory;GO:0006559 L-phenylalanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P17276-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42003-1", "uniprot_id": [ { "id": "MAD_DROME", "url": "https://www.uniprot.org/uniprot/P42003", "type": "external" } ], "mass": 50505.0, "length": 455, "protein_name": "Protein mothers against dpp", "gene_name": "Mad", "organism": "Fruit fly", "refseq_name": "mothers against dpp, isoform A", "refseq_ac": [ { "id": "NP_477017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477017", "type": "external" } ], "gene_names_uniprotkb": "Mad; 23; CG12399; Dmel\\CG12399; Dmel_CG12399; E(zen)2; En(vvl); MAD; Mat; P-Mad; P-mad; PMad; Smad1; Smad; apg; c28; dMAD; dMad; l(2)K00237; l(2)k00237; mad; p-MAD; p-Mad; pMAD; pMad; pSmad", "gene_names_refseq": "2/23; CG12399; Dmel\\CG12399; E(zen)2; En(vvl); MAD; Mad; Mat; P-Mad; P-mad; PMad; Smad1; Smad; apg; c28; dMAD; dMad; l(2)K00237; l(2)k00237; mad; p-MAD; p-Mad; pMAD; pMad; pSmad", "protein_names_uniprotkb": "Protein mothers against dpp", "protein_names_refseq": "CG12399-PA; Mad-PA; Mothers-against-decapentaplegic; apang; mathers against dpp; mother against Dpp; mother against decapentaplegic; mothers against decapentaplegic; mothers against dpp, isoform A; mothers against dpp; phospho-Smad; phosphoSmad; phosphorylated smad", "tax_id": 7227, "disease": "juvenile polyposis syndrome (Disease Ontology:DOID:0050787); arteriovenous malformations of the brain (Disease Ontology:DOID:0060688); prostate cancer (Disease Ontology:DOID:10283); nephrotic syndrome (Disease Ontology:DOID:1184); male infertility (Disease Ontology:DOID:12336); primary pulmonary hypertension (Disease Ontology:DOID:14557); glomerulonephritis (Disease Ontology:DOID:2921); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (dme:Dmel_CG12399); (R-DME-201451); (R-DME-5689880); (R-DME-8941326)", "pathway_count": 4, "publication_count": 37, "publication_id_list": "10320478;10731132;11071761;11703946;11997505;12537568;12537572;12537573;12537574;12705870;12754252;14534137;15296719;16109720;16110336;16951053;17507407;17569856;17569867;18327897;18820452;19451277;19557331;19766717;20036230;20547758;22563507;25589440;26109356;26109357;7705627;7768443;8702167;9230443;9502724;9502733;9694800", "class_list": "", "function": "Component of the Mad-Med transcription factor complex involved in the dpp/BMP TGF-beta signal transduction pathway (PubMed:15296719, PubMed:16109720, PubMed:7705627, PubMed:7768443, PubMed:8702167, PubMed:9230443, PubMed:9502724, PubMed:9694800). Acts downstream of the dpp-receptor protein serine/threonine kinase tkv/thickvein (PubMed:10320478). Becomes phosphorylated upon dpp-signaling, triggering association with Med and nuclear localization (PubMed:9502724, PubMed:9502733). Binds GC-rich enhancer sites with consensus sequence 5'-GCCGNCG-3' in the enhancer region of dpp-responsive genes (PubMed:15296719, PubMed:16109720, PubMed:9230443, PubMed:9694800). Mad-Med acts as a transcriptional activator but recruits shn/Shnurri to enhance its activity or switch to transcriptional repression (PubMed:11071761, PubMed:16109720). Regulates dpp-responsive genes by directly activating their expression or by repressing the transcriptional repressor brk/brinker (PubMed:12705870). Also involved in repression of other key developmental genes including bam and gsb (PubMed:15296719). Essential in the germline during oogenesis (PubMed:9502724). Required for dpp-signaling during dorsoventral patterning of the embryo (PubMed:14534137, PubMed:7768443, PubMed:9502733). Involved in anteroposterior patterning during wing imaginal disc growth (PubMed:17507407, PubMed:18820452, PubMed:7768443, PubMed:9230443)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 20, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQM3", "ec_number_list": [], "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0003713 transcription coactivator activity;GO:0046872 metal ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 3.8, "record_id": "P42003-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17133-1", "uniprot_id": [ { "id": "RU17_DROME", "url": "https://www.uniprot.org/uniprot/P17133", "type": "external" } ], "mass": 52901.0, "length": 448, "protein_name": "U1 small nuclear ribonucleoprotein 70 kDa", "gene_name": "snRNP-U1-70K", "organism": "Fruit fly", "refseq_name": "small ribonucleoprotein particle U1 subunit 70K, isoform C", "refseq_ac": [ { "id": "NP_001260173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260173", "type": "external" } ], "gene_names_uniprotkb": "snRNP-U1-70K; 70K; CG8749; Dm70K; Dmel\\CG8749; Dmel_CG8749; SnRNP-U1-70K; U1 70K snRNP; U1 70K; U1 70k; U1 snRNP; U1-70K; U1-70k; U170K; U1snRNP-70K; U1; dU1-70K; l(2)02107; snRNP 70K; snRNP27D; snRNP70K; snRNPU1-70K; snRNP", "gene_names_refseq": "70K; CG8749; Dm70K; Dmel\\CG8749; SnRNP-U1-70K; U1 70K snRNP; U1 70K; U1 70k; U1 snRNP; U1-70K; U1-70k; U170K; U1snRNP-70K; U1; dU1-70K; l(2)02107; snRNP 70K; snRNP-U1-70K; snRNP27D; snRNP70K; snRNPU1-70K; snRNP", "protein_names_uniprotkb": "U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70", "protein_names_refseq": "CG8749-PC; U1 snRNP-specific 70K protein; small nuclear ribonucleoprotein 70K; small ribonucleoprotein particle U1 subunit 70K, isoform C; snRNP-U1-70K-PC", "tax_id": 7227, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); disease of mental health (Disease Ontology:DOID:150); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dme:Dmel_CG8749); (R-DME-9770562)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10588732;10731132;12537568;12537569;12537572;12537573;12537574;15611175;15990112;16110336;1692955;17569856;17569867;18621711;24244416;25589440;26109356;26109357;40245499", "class_list": "", "function": "Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA (PubMed:15611175). Required during oogenesis for nurse cell chromatin dispersal (PubMed:24244416)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q564D5;Q9VM56", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0030619 U1 snRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0048025 negative regulation of mRNA splicing, via spliceosome;GO:0043484 regulation of RNA splicing;GO:0000398 mRNA splicing, via spliceosome;GO:0048477 oogenesis;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P17133-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16868-1", "uniprot_id": [ { "id": "FUZZY_DROME", "url": "https://www.uniprot.org/uniprot/O16868", "type": "external" } ], "mass": 46261.0, "length": 416, "protein_name": "Protein fuzzy", "gene_name": "fuz; fy", "organism": "Fruit fly", "refseq_name": "fuzzy, isoform B", "refseq_ac": [ { "id": "NP_001260250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260250", "type": "external" } ], "gene_names_uniprotkb": "fuz; fy; CG13396; Dmel\\CG13396; Dmel_CG13396; FY; Fy; fuzzy; fy", "gene_names_refseq": "CG13396; Dmel\\CG13396; FY; Fy; fy", "protein_names_uniprotkb": "Protein fuzzy", "protein_names_refseq": "CG13396-PB; fuzzy, isoform B; fuzzy; fy-PB", "tax_id": 7227, "disease": "ciliopathy (Disease Ontology:DOID:0060340); neural tube defect (Disease Ontology:DOID:0080074)", "pathway": " (dme:Dmel_CG13396); (R-DME-450728); (R-DME-5610787)", "pathway_count": 3, "publication_count": 18, "publication_id_list": "10731132;10924475;12537568;12537569;12537572;12537573;12537574;15556868;16110336;17569856;17569867;18701542;18723886;19576201;25589440;26109356;26109357;9374400", "class_list": "", "function": "Plays a role in the organization of cell polarity via a planar cell polarity (PCP) cascade. Involved in the development of the hairs on the wings. Specify the correct orientation of the hair by limiting the site of prehair initiation to the distal vertex of the wing cells. Controls wing cell hair number by maintaining the integrity of the cytoskeletal components that direct hair development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:1905515 non-motile cilium assembly;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "O16868-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P10676-1", "uniprot_id": [ { "id": "NINAC_DROME", "url": "https://www.uniprot.org/uniprot/P10676", "type": "external" } ], "mass": 174300.0, "length": 1501, "protein_name": "Neither inactivation nor afterpotential protein C", "gene_name": "ninaC", "organism": "Fruit fly", "refseq_name": "neither inactivation nor afterpotential C, isoform C", "refseq_ac": [ { "id": "NP_001260189", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260189", "type": "external" } ], "gene_names_uniprotkb": "ninaC; 2.2; CG 5125; CG5125; CG54125; CT16120; CT42491; DRONINAC; Dm NinaC; Dmel\\CG5125; Dmel_CG5125; Myo1B; NINA C; NINAC; Nina C; NinaC; ninac", "gene_names_refseq": "2.2; CG 5125; CG5125; CG54125; CT16120; CT42491; DRONINAC; Dm NinaC; Dmel\\CG5125; Myo1B; NINA C; NINAC; Nina C; NinaC; ninaC; ninac", "protein_names_uniprotkb": "Neither inactivation nor afterpotential protein C; 2.7.11.1", "protein_names_refseq": "CG5125-PC; NINAC myosin III; droninac; either inactivation nor afterpotential C; myosin-III; neither inactivation Nor afterpotential C; neither inactivation nor after potential C; neither inactivation nor afterpotential C, isoform C; neither inactivation nor afterpotential-C; ninaC-PC", "tax_id": 7227, "disease": "autosomal dominant nonsyndromic deafness 90 (Disease Ontology:DOID:0070607); autosomal recessive nonsyndromic deafness 30 (Disease Ontology:DOID:0110489)", "pathway": " (dme:Dmel_CG5125)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;20107052;20739554;2449973;25589440;25822849;26109356;26109357", "class_list": "", "function": "Required for photoreceptor cell function. The ninaC proteins combines putative serine/threonine-protein kinase and myosin activities (PubMed:2449973). Essential for the expression and stability of the rtp protein in the photoreceptors (PubMed:20107052). The rtp/ninaC complex is required for stability of inad and inac and the normal termination of phototransduction in the retina (PubMed:20739554)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P10677;Q8MRP1;Q9VM23;Q9VM24", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016028 rhabdomere;GO:0016027 inaD signaling complex;GO:0033583 rhabdomere membrane", "go_biological_process": "GO:0030832 regulation of actin filament length;GO:0006886 intracellular protein transport;GO:0007010 cytoskeleton organization;GO:0007601 visual perception;GO:0007603 phototransduction, visible light", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P10676-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O44252-1", "uniprot_id": [ { "id": "ROST_DROME", "url": "https://www.uniprot.org/uniprot/O44252", "type": "external" } ], "mass": 32635.0, "length": 275, "protein_name": "Protein rolling stone", "gene_name": "rost", "organism": "Fruit fly", "refseq_name": "rolling stone, isoform B", "refseq_ac": [ { "id": "NP_001260274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260274", "type": "external" } ], "gene_names_uniprotkb": "rost; CG9552; Dmel\\CG9552; Dmel_CG9552", "gene_names_refseq": "CG9552; Dmel\\CG9552; rost", "protein_names_uniprotkb": "Protein rolling stone", "protein_names_refseq": "CG9552-PB; rolling stone, isoform B; rost-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9552)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9230076", "class_list": "", "function": "May have a central role in the fusion process during myogenesis, within the somatic mesoderm., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5U0W2;Q95RK6;Q9VLF9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0007520 myoblast fusion", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "O44252-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VIH7-1", "uniprot_id": [ { "id": "SKY_DROME", "url": "https://www.uniprot.org/uniprot/Q9VIH7", "type": "external" } ], "mass": 67328.0, "length": 587, "protein_name": "GTPase-activating protein skywalker", "gene_name": "sky", "organism": "Fruit fly", "refseq_name": "skywalker, isoform I", "refseq_ac": [ { "id": "NP_001163026", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163026", "type": "external" } ], "gene_names_uniprotkb": "sky; CG14399; CG9339; CG9340; Dmel\\CG9339; Dmel_CG9339; Sky; anon-WO0118547.455", "gene_names_refseq": "CG14399; CG9339; CG9340; Dmel\\CG9339; Sky; anon-WO0118547.455; sky", "protein_names_uniprotkb": "GTPase-activating protein skywalker", "protein_names_refseq": "CG9339-PI; sky-PI; skywalker, isoform I; skywalker", "tax_id": 7227, "disease": "nonsyndromic deafness (Disease Ontology:DOID:0050563); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); developmental and epileptic encephalopathy 16 (Disease Ontology:DOID:0080449); autosomal recessive nonsyndromic deafness 86 (Disease Ontology:DOID:0110532); autosomal dominant nonsyndromic deafness 65 (Disease Ontology:DOID:0110586); DOORS syndrome (Disease Ontology:DOID:0111627); Rolandic epilepsy-paroxysmal exercise-induced dystonia-writer's cramp syndrome (Disease Ontology:DOID:0111645); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG9339)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;21458671;25422373;25589440;26109356;26109357;27669036", "class_list": "", "function": "GTPase-activating protein (GAP) for Rab35 which regulates synaptic vesicle (SV) protein recycling and turnover at the neuromuscular junction boutons and possibly ventral nerve cord via endosomal trafficking (PubMed:21458671, PubMed:25422373, PubMed:27669036). Inhibits Rab35-mediated endosomal sorting which traffics old or dysfunctional SV proteins through a degradative endolysosomal route that involves the ESCRT pathway and the HOPS complex members dor, vps39 and rab7 (PubMed:21458671, PubMed:25422373). This function is essential for preventing excessive degradation and turnover of vesicles from the readily releasable pool which leads to increased neurotransmission and eventually neurodegeneration (PubMed:21458671, PubMed:25422373, PubMed:27669036). Preferentially binds phosphoinositides phosphorylated at the D5 position of the inositol ring, such as phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3) (PubMed:27669036). Binding to phosphoinositides and thus membrane-association, is required for its function in regulating the turnover of synaptic-vesicle proteins (PubMed:27669036). It is therefore likely that it is recruited to vesicle membranes with high phosphoinositide content and thereby selectively prevents endolysosomal degradation of these vesicles (PubMed:27669036)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DML7;Q8INU4;Q8MSY5;Q8MT51;Q8T0D2", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031594 neuromuscular junction;GO:0043195 terminal bouton;GO:0045202 synapse;GO:0098794 postsynapse", "go_biological_process": "GO:0036466 synaptic vesicle recycling via endosome;GO:0007274 neuromuscular synaptic transmission;GO:0031175 neuron projection development;GO:0007268 chemical synaptic transmission;GO:0046929 negative regulation of neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VIH7-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O76927-1", "uniprot_id": [ { "id": "RS21_DROME", "url": "https://www.uniprot.org/uniprot/O76927", "type": "external" } ], "mass": 9167.0, "length": 83, "protein_name": "Small ribosomal subunit protein eS21", "gene_name": "RpS21", "organism": "Fruit fly", "refseq_name": "ribosomal protein S21, isoform F", "refseq_ac": [ { "id": "NP_001259970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259970", "type": "external" } ], "gene_names_uniprotkb": "RpS21; 14; CG2986; Dmel\\CG2986; Dmel_CG2986; M(2)23B; S21e; S21; l(2)03575; l(2)k16814; oho23B; oho23; rpS21", "gene_names_refseq": "CG2986; Dmel\\CG2986; M(2)23B; RpS21; S21e; S21; l(2)03575; l(2)168/14; l(2)k16814; oho23B; oho23; rpS21", "protein_names_uniprotkb": "Small ribosomal subunit protein eS21; 40S ribosomal protein S21; Overgrown hematopoietic organs at 23B", "protein_names_refseq": "CG2986-PF; Rp S21; RpS21-PF; overgrown hematopoietic organs 23B; overgrown hematopoietic organs at 23B; overgrown hematopoietic organs-23; ribosomal protein S21, isoform F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2986); (R-DME-156827); (R-DME-1799339); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 12, "publication_count": 13, "publication_id_list": "10022917;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357", "class_list": "", "function": "May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V027", "ec_number_list": [], "go_molecular_function": "GO:0043022 ribosome binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0005840 ribosome;GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0042127 regulation of cell population proliferation;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181 cytoplasmic translation;GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "O76927-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41126-1", "uniprot_id": [ { "id": "RL13_DROME", "url": "https://www.uniprot.org/uniprot/P41126", "type": "external" } ], "mass": 24951.0, "length": 218, "protein_name": "Large ribosomal subunit protein eL13", "gene_name": "RpL13", "organism": "Fruit fly", "refseq_name": "ribosomal protein L13, isoform B", "refseq_ac": [ { "id": "NP_001033891", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033891", "type": "external" } ], "gene_names_uniprotkb": "RpL13; Bbc1; CG4651; Dmbbc1; Dmel\\CG4651; Dmel_CG4651; L13e; L13; RPL13; Rp L13; Rpl13; anon-EST:fe1D1; bbc1; rpL13", "gene_names_refseq": "Bbc1; CG4651; Dmbbc1; Dmel\\CG4651; L13e; L13; RPL13; Rp L13; RpL13; Rpl13; anon-EST:fe1D1; bbc1; rpL13", "protein_names_uniprotkb": "Large ribosomal subunit protein eL13; 60S ribosomal protein L13; BBC1 protein homolog", "protein_names_refseq": "CG4651-PB; RpL13-PB; anon-fast-evolving-1D1; r-protein L13; ribosomal protein L13, isoform B", "tax_id": 7227, "disease": "spondyloepimetaphyseal dysplasia (Disease Ontology:DOID:0080027); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (dme:Dmel_CG4651); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;7557437", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs (Probable)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0I6;B7FNN5;Q9VL55", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P41126-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9PFN0-1", "uniprot_id": [ { "id": "HZG_DROME", "url": "https://www.uniprot.org/uniprot/M9PFN0", "type": "external" } ], "mass": 40326.0, "length": 352, "protein_name": "Phosphatase Herzog", "gene_name": "hzg", "organism": "Fruit fly", "refseq_name": "herzog, isoform B", "refseq_ac": [ { "id": "NP_001261912", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261912", "type": "external" } ], "gene_names_uniprotkb": "hzg; 24664944; CG5830", "gene_names_refseq": "24664944; CG5830; Dmel\\CG5830; hzg", "protein_names_uniprotkb": "Phosphatase Herzog; 3.1.3.16", "protein_names_refseq": "CG5830-PB; herzog, isoform B; herzog; hzg-PB", "tax_id": 7227, "disease": "lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dme:Dmel_CG5830)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;31491385", "class_list": "", "function": "Prion-like membrane-associated phosphatase (PubMed:31491385). Phosphatase activity depends on amyloid-like assembly at the membrane (PubMed:31491385). Might have a role in establishment of segment polarity in embryos (PubMed:31491385)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7YU53;Q9VUX0", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0004721 phosphoprotein phosphatase activity;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0040019 positive regulation of embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "M9PFN0-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20232-1", "uniprot_id": [ { "id": "TFS2_DROME", "url": "https://www.uniprot.org/uniprot/P20232", "type": "external" } ], "mass": 34300.0, "length": 313, "protein_name": "Transcription elongation factor S-II", "gene_name": "TfIIS", "organism": "Fruit fly", "refseq_name": "RNA polymerase II elongation factor, isoform B", "refseq_ac": [ { "id": "NP_001260457", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260457", "type": "external" } ], "gene_names_uniprotkb": "TfIIS; BG:DS00929.12; CG3710; DmS-II; DmSII; Dmel\\CG3710; Dmel_CG3710; IIS; RnpSII; TFIISA; TFIIS; TFS-II; br52; l(2)35Cf; l(2)35cF; l(2)br52; l35Cf", "gene_names_refseq": "BG:DS00929.12; CG3710; DmS-II; DmSII; Dmel\\CG3710; IIS; RnpSII; TFIISA; TFIIS; TFS-II; TfIIS; br52; l(2)35Cf; l(2)35cF; l(2)br52; l35Cf", "protein_names_uniprotkb": "Transcription elongation factor S-II; RNA polymerase II elongation factor DMS-II; TFIIS", "protein_names_refseq": "CG3710-PB; RNA polymerase II elongation factor, isoform B; TfIIS-PB; lethal(2)35Cf; transcription cleavage factor IIS", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3710); (R-DME-112382); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-75955)", "pathway_count": 8, "publication_count": 15, "publication_id_list": "10471707;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;2243775;25589440;26109356;26109357;7772609", "class_list": "", "function": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V3M8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003711 transcription elongation factor activity;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P20232-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P13008-1", "uniprot_id": [ { "id": "RS26_DROME", "url": "https://www.uniprot.org/uniprot/P13008", "type": "external" } ], "mass": 13267.0, "length": 114, "protein_name": "Small ribosomal subunit protein eS26", "gene_name": "RpS26", "organism": "Fruit fly", "refseq_name": "ribosomal protein S26, isoform D", "refseq_ac": [ { "id": "NP_001260537", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260537", "type": "external" } ], "gene_names_uniprotkb": "RpS26; CG10305; Dmel\\CG10305; Dmel_CG10305; M(2)36F; M(2)S13; M(2)m; M[[s]]; RPS26; Rps26; S26e; anon-EST:fe2A3; l(2)04553; l(2)36Fa; rpS26; rpS31", "gene_names_refseq": "CG10305; Dmel\\CG10305; M(2)36F; M(2)S13; M(2)m; M[[s]]; RPS26; RpS26; Rps26; S26e; anon-EST:fe2A3; l(2)04553; l(2)36Fa; rpS26; rpS31", "protein_names_uniprotkb": "Small ribosomal subunit protein eS26; 40S ribosomal protein S26; DS31", "protein_names_refseq": "CG10305-PD; RpS26-PD; anon-fast-evolving-2A3; minute (2) 36F; ribosomal protein S26, isoform D; ribosomal protein S31", "tax_id": 7227, "disease": "Diamond-Blackfan anemia 10 (Disease Ontology:DOID:0111888); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (dme:Dmel_CG10305); (R-DME-156827); (R-DME-1799339); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 12, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;2911474;2928115", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0T7;C0PV38;P10380;Q0E8P4;Q9VJ88", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:0022626 cytosolic ribosome;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022627 cytosolic small ribosomal subunit;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P13008-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25161-1", "uniprot_id": [ { "id": "PSMD3_DROME", "url": "https://www.uniprot.org/uniprot/P25161", "type": "external" } ], "mass": 56004.0, "length": 494, "protein_name": "Probable 26S proteasome non-ATPase regulatory subunit 3", "gene_name": "Rpn3", "organism": "Fruit fly", "refseq_name": "regulatory particle non-ATPase 3, isoform B", "refseq_ac": [ { "id": "NP_001260557", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260557", "type": "external" } ], "gene_names_uniprotkb": "Rpn3; CG10484; CG42641; DXA2_DROME; Dmel\\CG42641; Dmel_CG42641; Dox-A2; DoxA2; Dox; RPN3; S3; l(2)37Bf[+]; l(2)37Bf; p58", "gene_names_refseq": "CG10484; CG42641; DXA2_DROME; Dmel\\CG42641; Dox-A2; DoxA2; Dox; RPN3; Rpn3; S3; l(2)37Bf[+]; l(2)37Bf; p58", "protein_names_uniprotkb": "Probable 26S proteasome non-ATPase regulatory subunit 3; 26S proteasome subunit S3; DOX-A2; Diphenol oxidase A2 component; Regulatory particle non-ATPase 3", "protein_names_refseq": "3; CG42641-PB; Rpn3-PB; diphenol oxidase A2; diphenol oxidase-A2; regulatory particle non-ATPase 3, isoform B; regulatory particle nonATPase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42641); (R-DME-1169091); (R-DME-1234176); (R-DME-1236978); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209406); (R-DME-209461); (R-DME-216167); (R-DME-2467813); (R-DME-2871837); (R-DME-350562); (R-DME-382556); (R-DME-432395); (R-DME-432524); (R-DME-432626); (R-DME-450408); (R-DME-4608870); (R-DME-4641257); (R-DME-4641258); (R-DME-5358346); (R-DME-538864); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5632684); (R-DME-5658442); (R-DME-5676590); (R-DME-5689603); (R-DME-5689880); (R-DME-6798695); (R-DME-68867); (R-DME-68949); (R-DME-69017); (R-DME-69601); (R-DME-75815); (R-DME-8854050); (R-DME-8939236); (R-DME-8939902); (R-DME-8941858); (R-DME-8948751); (R-DME-8951664); (R-DME-9020702); (R-DME-9755511); (R-DME-9762114); (R-DME-983168); (R-DME-9907900); (R-DME-9929491); (R-DME-9932298); (R-DME-9954709)", "pathway_count": 57, "publication_count": 46, "publication_id_list": "10102270;10417378;10458606;10481010;10731132;11585911;12231619;12421421;12432393;12442174;12537568;12537569;12537572;12537573;12537574;12973300;15178801;15258584;15331761;16110336;16139204;16299518;16326393;16386907;16543224;16603629;16651542;16740475;16794082;17102630;17569856;17569867;17925225;18519643;18593878;1909680;19185492;25589440;26109356;26109357;7705656;8948598;9025065;9215627;9553105;9990853", "class_list": "", "function": "Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B5RIX5;Q8T460;Q9VJ09", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex;GO:0008541 proteasome regulatory particle, lid subcomplex;GO:0005838 proteasome regulatory particle", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0042176 regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 4.7, "record_id": "P25161-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P19889-1", "uniprot_id": [ { "id": "RLA0_DROME", "url": "https://www.uniprot.org/uniprot/P19889", "type": "external" } ], "mass": 34202.0, "length": 317, "protein_name": "Large ribosomal subunit protein uL10", "gene_name": "RpLP0", "organism": "Fruit fly", "refseq_name": "ribosomal protein LP0, isoform B", "refseq_ac": [ { "id": "NP_001262202", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262202", "type": "external" } ], "gene_names_uniprotkb": "RpLP0; AP3; Ap3; Ape; CG7490; Dmel\\CG7490; Dmel_CG7490; L10; LP0; P0; P35; PO; RLA0; RPL P0; RpP0; RpPO; Rplp0; l(3)01544; l(3)0154; p0", "gene_names_refseq": "AP3; Ap3; Ape; CG7490; Dmel\\CG7490; L10; LP0; P0; P35; PO; RLA0; RPL P0; RpLP0; RpP0; RpPO; Rplp0; l(3)01544; l(3)0154; p0", "protein_names_uniprotkb": "Large ribosomal subunit protein uL10; 3.1.-.-; 60S acidic ribosomal protein P0; Apurinic-apyrimidinic endonuclease", "protein_names_refseq": "60S ribosomal protein P0; ACIDIC RIBOSOMAL PROTEIN LP0; CG7490-PB; RpLP0-PB; apurinic endonuclease 3; ribosomal protein LP0, isoform B; ribosomal protein P0", "tax_id": 7227, "disease": "Down syndrome (Disease Ontology:DOID:14250)", "pathway": " (dme:Dmel_CG7490); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;1870984;2471063;25589440;26109356;26109357;8932386", "class_list": "", "function": "Ribosomal protein P0 is the functional equivalent of E.coli protein L10., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BHX7;Q9VNV9", "ec_number_list": [ { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005509 calcium ion binding;GO:0003735 structural constituent of ribosome;GO:0070180 large ribosomal subunit rRNA binding;GO:0052720 class II DNA-(apurinic or apyrimidinic site) endonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016363 nuclear matrix;GO:0005840 ribosome;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0006284 base-excision repair;GO:0042254 ribosome biogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P19889-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O76878-1", "uniprot_id": [ { "id": "RIPL_DROME", "url": "https://www.uniprot.org/uniprot/O76878", "type": "external" } ], "mass": 50147.0, "length": 443, "protein_name": "RILP-like protein homolog", "gene_name": "Rilpl", "organism": "Fruit fly", "refseq_name": "Rab interacting lysosomal protein like, isoform A", "refseq_ac": [ { "id": "NP_569910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569910", "type": "external" } ], "gene_names_uniprotkb": "Rilpl; CG11448; Dmel\\CG11448; Dmel_CG11448; EG:132E8.4; RILP", "gene_names_refseq": "CG11448; Dmel\\CG11448; EG:132E8.4; RILP; Rilpl", "protein_names_uniprotkb": "RILP-like protein homolog; Rab-interacting lysosomal protein-like", "protein_names_refseq": "CG11448-PA; Rab interacting lysosomal protein like, isoform A; Rilpl-PA", "tax_id": 7227, "disease": "oculopharyngodistal myopathy 4 (Disease Ontology:DOID:0081300)", "pathway": " (dme:Dmel_CG11448)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;30115618", "class_list": "", "function": "May have a role in lysosome distribution by interacting with Arl8., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0030742 GTP-dependent protein binding;GO:0051959 dynein light intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane;GO:0036064 ciliary basal body", "go_biological_process": "GO:0060271 cilium assembly;GO:0032418 lysosome localization", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "O76878-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O61307-1", "uniprot_id": [ { "id": "TENM_DROME", "url": "https://www.uniprot.org/uniprot/O61307", "type": "external" } ], "mass": 304056.0, "length": 2731, "protein_name": "Teneurin-m", "gene_name": "Ten-m", "organism": "Fruit fly", "refseq_name": "tenascin major, isoform D", "refseq_ac": [ { "id": "NP_001097661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097661", "type": "external" } ], "gene_names_uniprotkb": "Ten-m; 2017; 5301; BcDNA:AT25108; CG11452; CG5723; CT16449; Dmel\\CG5723; Dmel_CG5723; Odz; Ten-M; Ten-mc; Ten79E; Ten[m]; l(3)00844; l(3)05301; l(3)05309; l(3)rJ307; l(3)rL201; l(3)rP126; odd(Oz); odz; ten(m); ten-m; ten[m]", "gene_names_refseq": "2017; 5301; BcDNA:AT25108; CG11452; CG5723; CT16449; Dmel\\CG5723; Odz; Ten-M; Ten-mc; Ten-m; Ten79E; Ten[m]; l(3)00844; l(3)05301; l(3)05309; l(3)rJ307; l(3)rL201; l(3)rP126; odd(Oz); odz/ten-m; odz; ten(m); ten-m/odz; ten-m; ten[m]", "protein_names_uniprotkb": "Teneurin-m; Odd Oz protein; Tenascin-like protein; Tenm", "protein_names_refseq": "CG5723-PD; Ten-m-PD; Teneurin-m; odd Oz; odd-Oz; tenascin major, isoform D; tenascin major; tenascin-like molecule major; tenascin-major; teneurin", "tax_id": 7227, "disease": "essential tremor 5 (Disease Ontology:DOID:0111432); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG5723)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;17893096;21857973;22425994;22426000;25589440;26109356;26109357;7514504;8070401;9373139", "class_list": "", "function": "Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Acts as a homophilic and heterophilic synaptic cell adhesion molecule that drives synapse assembly. Promotes bi-directional trans-synaptic signaling with Ten-a to organize neuromuscular synapses. Functions in olfactory synaptic partner matching by promoting homophilic cell adhesion between pre-synaptic olfactory receptor neurons (ORN) axons and post-synaptic projection neurons (PN) dendrites partner in the developing antennal lobe to form stable connections. Also required for peripheral axon growth cone guidance and target recognition of motor neurons., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 2, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 5, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 5, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 2, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 2, "disease_count": 2, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "A8JNW8;O18366;Q24551;Q9TX59;Q9VNU6", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0031005 filamin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0031594 neuromuscular junction;GO:0043025 neuronal cell body", "go_biological_process": "GO:2000331 regulation of terminal button organization;GO:0048790 maintenance of presynaptic active zone structure;GO:0007155 cell adhesion;GO:0007274 neuromuscular synaptic transmission;GO:0050808 synapse organization", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "O61307-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000100000000000.1000000001000.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42124-1", "uniprot_id": [ { "id": "EZ_DROME", "url": "https://www.uniprot.org/uniprot/P42124", "type": "external" } ], "mass": 86935.0, "length": 760, "protein_name": "Histone-lysine N-methyltransferase E(z)", "gene_name": "E(z)", "organism": "Fruit fly", "refseq_name": "enhancer of zeste, isoform B", "refseq_ac": [ { "id": "NP_001137932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137932", "type": "external" } ], "gene_names_uniprotkb": "E(z); 2; CG6502; Dmel\\CG6502; Dmel_CG6502; E(Z); E(z)1; E(z); EZH2; EZ; E[z]; Ezh2; Ez; KMT6; Su(z)301; dE(z); l(3)1902; l(3)67Fa; l(3)B12; l(3)SG17; l(3)ds12; pco", "gene_names_refseq": "CG6502; Dmel\\CG6502; E(Z); E(z)1; E(z); EZH1/2; EZH2; EZ; E[z]; Ezh2; Ez; Su(z)301; dE(z); l(3)1902; l(3)67Fa; l(3)B12; l(3)SG17; l(3)ds12; pco/E(z); pco", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase E(z); 2.1.1.356; Lysine N-methyltransferase 6; Protein enhancer of zeste", "protein_names_refseq": "CG6502-PB; E(z)-PB; enhancer of zeste, isoform B; enhancer of zeste; enhancer of zest; enhancer-of-zeste; polycombeotic", "tax_id": 7227, "disease": "diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); syndromic intellectual disability (Disease Ontology:DOID:0050888); myelodysplastic syndrome (Disease Ontology:DOID:0050908); chronic myelomonocytic leukemia (Disease Ontology:DOID:0080188); colorectal carcinoma (Disease Ontology:DOID:0080199); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); leiomyoma (Disease Ontology:DOID:127); lung cancer (Disease Ontology:DOID:1324); Weaver syndrome (Disease Ontology:DOID:14731); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); endometriosis (Disease Ontology:DOID:289); invasive ductal carcinoma (Disease Ontology:DOID:3008); glioblastoma (Disease Ontology:DOID:3068); osteosarcoma (Disease Ontology:DOID:3347); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); cholangiocarcinoma (Disease Ontology:DOID:4947); myelofibrosis (Disease Ontology:DOID:4971); renal Wilms' tumor (Disease Ontology:DOID:5176); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); B-cell lymphoma (Disease Ontology:DOID:707); malignant pleural mesothelioma (Disease Ontology:DOID:7474); abdominal aortic aneurysm (Disease Ontology:DOID:7693); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute megakaryocytic leukemia (Disease Ontology:DOID:8761); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG6502); (R-DME-212300); (R-DME-2559580); (R-DME-8943724); (R-DME-8953750); (R-DME-9764725); (R-DME-9909649)", "pathway_count": 7, "publication_count": 25, "publication_id_list": "10731132;11124122;11581156;12408863;12408864;12533794;12537568;12537569;12537572;12537573;12537574;12697833;12771214;16110336;17569856;17569867;18327897;22354997;25589440;25620564;26109356;26109357;8413234;9012527;9566901", "class_list": "", "function": "Polycomb group (PcG) protein. Catalytic subunit of the Esc/E(z) complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (PubMed:22354997). As part of the PRC2 complex methylates the PRC2 accessory protein Jarid2 on 'Lys-46' (PubMed:25620564). While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state. The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting that the recruitment of the distinct PRC1 complex is also required. Required for recruitment of the PRC2 complex to chromatin and H3K27me3 histone modification (PubMed:22354997)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 38, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B7Z0G2;Q9VTA3", "ec_number_list": [ { "id": "2.1.1.356", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.356", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042054 histone methyltransferase activity;GO:0043565 sequence-specific DNA binding;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0035098 ESC/E(Z) complex;GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P42124-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O61231-1", "uniprot_id": [ { "id": "RL10_DROME", "url": "https://www.uniprot.org/uniprot/O61231", "type": "external" } ], "mass": 25528.0, "length": 218, "protein_name": "Large ribosomal subunit protein uL16", "gene_name": "RpL10", "organism": "Fruit fly", "refseq_name": "ribosomal protein L10, isoform E", "refseq_ac": [ { "id": "NP_001262233", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262233", "type": "external" } ], "gene_names_uniprotkb": "RpL10; BcDNA:LD24589; CG17521; DQM; Dmel\\CG17521; Dmel_CG17521; L10; L16; Qm; Rp L10; anon-EST:Posey179; qm; rpL10", "gene_names_refseq": "BcDNA:LD24589; CG17521; DQM; Dmel\\CG17521; L10; L16; Qm; Rp L10; RpL10; anon-EST:Posey179; qm; rpL10", "protein_names_uniprotkb": "Large ribosomal subunit protein uL16; 60S ribosomal protein L10; QM protein homolog; dQM", "protein_names_refseq": "60S ribosomal protein L10; CG17521-PE; Qm; RpL10-PE; ribosomal protein L10, isoform E; ribosome RL10", "tax_id": 7227, "disease": "syndromic X-linked intellectual disability Najm type (Disease Ontology:DOID:0060807); syndromic X-linked mental retardation 35 (Disease Ontology:DOID:0080241); spermatogenic failure 63 (Disease Ontology:DOID:0112356); autistic disorder (Disease Ontology:DOID:12849); spondyloepiphyseal dysplasia congenita (Disease Ontology:DOID:14789); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603)", "pathway": " (dme:Dmel_CG17521); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;9524813", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8B5;Q86NY2;Q9I813;Q9W5T1", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit;GO:0005840 ribosome", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "O61231-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O02372-1", "uniprot_id": [ { "id": "LUSH_DROME", "url": "https://www.uniprot.org/uniprot/O02372", "type": "external" } ], "mass": 17437.0, "length": 153, "protein_name": "General odorant-binding protein lush", "gene_name": "lush", "organism": "Fruit fly", "refseq_name": "lush, isoform B", "refseq_ac": [ { "id": "NP_001163468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163468", "type": "external" } ], "gene_names_uniprotkb": "lush; CG8807; Obp76a; Obp76c", "gene_names_refseq": "76a; 76c(LUSH); 76c; CG8807; DmelOBP76a; DmelObp76a; Dmel\\CG8807; LUSH; Lush; OBP LUSH; OBP76a; Obp76a (LUSH); Obp76a; lush; obp76a", "protein_names_uniprotkb": "General odorant-binding protein lush", "protein_names_refseq": "CG8807-PB; LUSH; lush, isoform B; lush-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8807)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;11238251;11729153;11754509;12537572;12881720;14759510;15664171;16928861;17943085;18585358;9755202", "class_list": "", "function": "Odorant-binding protein required for olfactory behavior and for activity of pheromone-sensitive neurons (PubMed:11238251, PubMed:14759510, PubMed:16928861, PubMed:17943085, PubMed:18585358, PubMed:9755202). Binds to alcohols and mediates avoidance behavior to high concentrations of alcohols, the alcohol-binding possibly resulting in activation of receptors on T2B neurons, the activation of these receptors inhibiting these neurons (PubMed:14759510, PubMed:9755202). Acts in concert with Snmp and lush to capture 11-cis vaccenyl acetate (cVA) molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex (PubMed:16928861, PubMed:17943085, PubMed:18585358). Acts as an adapter that bridges cVA with its receptor: directly binds cVA, resulting in a conformational change that turns the inactive Lush into an active ligand of the pheromone receptor Or67d on T1 olfactory neurons (PubMed:15664171, PubMed:16928861). T1 neurons are excited by the pheromone VA, while T2 neurons are inhibited by alcohols (PubMed:16928861). Also binds to phthalates (PubMed:14759510)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E1JI39;Q29QG4", "ec_number_list": [], "go_molecular_function": "GO:0005550 pheromone binding;GO:0005549 odorant binding;GO:0035275 dibutyl phthalate binding;GO:0035274 diphenyl phthalate binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0042048 olfactory behavior;GO:0045471 response to ethanol;GO:0007608 sensory perception of smell;GO:0019236 response to pheromone;GO:0007619 courtship behavior", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "O02372-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16129-1", "uniprot_id": [ { "id": "SYFM_DROME", "url": "https://www.uniprot.org/uniprot/O16129", "type": "external" } ], "mass": 51996.0, "length": 453, "protein_name": "Probable phenylalanine--tRNA ligase, mitochondrial", "gene_name": "PheRS-m", "organism": "Fruit fly", "refseq_name": "Phenylalanyl-tRNA synthetase, mitochondrial", "refseq_ac": [ { "id": "NP_477283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477283", "type": "external" } ], "gene_names_uniprotkb": "PheRS-m; Aats-phe-m; Aats-phe; CG13348; Pts", "gene_names_refseq": "Aats-phe-m; Aats-phe; CG13348; Dmel\\CG13348; FRS; PheRS-m; PheRS; Pts; dFARS2; dFARS; mtPheRS", "protein_names_uniprotkb": "Probable phenylalanine--tRNA ligase, mitochondrial; 6.1.1.20; PheRS; Phenylalanyl-tRNA synthetase", "protein_names_refseq": "CG13348-PA; PheRS-m-PA; Phenylalanyl-tRNA synthetase, mitochondrial; Phenylalanyl-tRNA synthetase; mitochondrial phenylalanyl-tRNA synthetase", "tax_id": 7227, "disease": "hereditary spastic paraplegia 77 (Disease Ontology:DOID:0110822); combined oxidative phosphorylation deficiency 14 (Disease Ontology:DOID:0111477); developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202)", "pathway": " (dme:Dmel_CG13348)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;9662479", "class_list": "", "function": "Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V6V8", "ec_number_list": [ { "id": "6.1.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.20", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0000049 tRNA binding;GO:0004826 phenylalanine-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0008033 tRNA processing;GO:0006432 phenylalanyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O16129-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16130-1", "uniprot_id": [ { "id": "RL39_DROME", "url": "https://www.uniprot.org/uniprot/O16130", "type": "external" } ], "mass": 6299.0, "length": 51, "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RpL39", "organism": "Fruit fly", "refseq_name": "ribosomal protein L39", "refseq_ac": [ { "id": "NP_477314", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477314", "type": "external" } ], "gene_names_uniprotkb": "RpL39; CG3997; RpL46; rp46", "gene_names_refseq": "BcDNA:RH27094; CG3997; Dmel\\CG3997; L39e; L39; RPl46; Rp46; RpL39; RpL46; anon-EST:Posey16; rp46", "protein_names_uniprotkb": "Large ribosomal subunit protein eL39; 60S ribosomal protein L39; Ribosomal protein 46", "protein_names_refseq": "CG3997-PA; RpL39-PA; ribosomal protein L39; ribosomal protein L46", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3997); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;23636399", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W1B7", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O16130-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16797-1", "uniprot_id": [ { "id": "RL3_DROME", "url": "https://www.uniprot.org/uniprot/O16797", "type": "external" } ], "mass": 46916.0, "length": 416, "protein_name": "Large ribosomal subunit protein uL3", "gene_name": "RpL3", "organism": "Fruit fly", "refseq_name": "ribosomal protein L3, isoform A", "refseq_ac": [ { "id": "NP_524316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524316", "type": "external" } ], "gene_names_uniprotkb": "RpL3; CG4863", "gene_names_refseq": "CG4863; Dmel\\CG4863; L3; RpL3; Rpl3; anon-EST:GressD4; chr3R:7047878..7048035; rpL3", "protein_names_uniprotkb": "Large ribosomal subunit protein uL3; 60S ribosomal protein L3", "protein_names_refseq": "CG4863-PA; RpL3-PA; ribosomal protein L3, isoform A; ribosomal protein L3", "tax_id": 7227, "disease": "Shwachman-Diamond syndrome (Disease Ontology:DOID:0060479); dilated cardiomyopathy 2D (Disease Ontology:DOID:0081160)", "pathway": " (dme:Dmel_CG4863); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "10731132;12537572;23636399;9661671", "class_list": "", "function": "The L3 protein is a component of the large subunit of cytoplasmic ribosomes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0KI83;Q6NNE9;Q9VGR4;Q9VGR5;Q9VGR6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O16797-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16810-1", "uniprot_id": [ { "id": "ORC1_DROME", "url": "https://www.uniprot.org/uniprot/O16810", "type": "external" } ], "mass": 103281.0, "length": 924, "protein_name": "Origin recognition complex subunit 1", "gene_name": "Orc1", "organism": "Fruit fly", "refseq_name": "origin recognition complex subunit 1", "refseq_ac": [ { "id": "NP_477303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477303", "type": "external" } ], "gene_names_uniprotkb": "Orc1; CG10667", "gene_names_refseq": "CG10667; DmORC1; DmOrc1p; DmOrc1; Dmel\\CG10667; ORC1; ORC; Orc1; dORC1; fs(2)SC46; orc1; rDmORC; sat", "protein_names_uniprotkb": "Origin recognition complex subunit 1; DmORC1", "protein_names_refseq": "CG10667-PA; Orc1-PA; origin recognition complex 1; origin recognition complex subunit 1; satin", "tax_id": 7227, "disease": "Meier-Gorlin syndrome 1 (Disease Ontology:DOID:0080512)", "pathway": " (dme:Dmel_CG10667); (R-DME-176187); (R-DME-68616); (R-DME-68689); (R-DME-68949); (R-DME-68962)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;9363940", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V4N1", "ec_number_list": [], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005664 nuclear origin of replication recognition complex", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0033314 mitotic DNA replication checkpoint signaling;GO:0006277 DNA amplification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O16810-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O16867-1", "uniprot_id": [ { "id": "TAP_DROME", "url": "https://www.uniprot.org/uniprot/O16867", "type": "external" } ], "mass": 44851.0, "length": 398, "protein_name": "Basic helix-loop-helix neural transcription factor TAP", "gene_name": "tap", "organism": "Fruit fly", "refseq_name": "target of poxn", "refseq_ac": [ { "id": "NP_524124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524124", "type": "external" } ], "gene_names_uniprotkb": "tap; CG7659; bps", "gene_names_refseq": "CG7659; Dmel\\CG7659; TAP; Tap; bHLHc9; bps; l(3)01658; tap", "protein_names_uniprotkb": "Basic helix-loop-helix neural transcription factor TAP; Protein biparous; Target of Poxn protein", "protein_names_refseq": "CG7659-PA; biparous; tap-PA; target of Pox-n; target of poxn", "tax_id": 7227, "disease": "congenital malabsorptive diarrhea 4 (Disease Ontology:DOID:0060779); glucose intolerance (Disease Ontology:DOID:10603); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG7659)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;8954743;9210583;9551861", "class_list": "", "function": "May play a role in the specification of the sugar-sensitive adult gustatory neuron and affect the response to sugar and salt. Regulated by POXN., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "P91640;Q9VVF9", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007411 axon guidance;GO:0061564 axon development;GO:0048843 negative regulation of axon extension involved in axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O16867-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O18334-1", "uniprot_id": [ { "id": "RAB6_DROME", "url": "https://www.uniprot.org/uniprot/O18334", "type": "external" } ], "mass": 23480.0, "length": 208, "protein_name": "Ras-related protein Rab6", "gene_name": "Rab6", "organism": "Fruit fly", "refseq_name": "Rab6, isoform B", "refseq_ac": [ { "id": "NP_001285869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285869", "type": "external" } ], "gene_names_uniprotkb": "Rab6; 6; AAF53168; CG6601; DRab6; Dm Rab6; DmRab6; Dmel\\CG6601; Dmel_CG6601; Drab6; O18334; dRab6; drab6; l(2)08323; rab6; wrt", "gene_names_refseq": "136/6; AAF53168; CG6601; DRab6; Dm Rab6; DmRab6; Dmel\\CG6601; Drab6; O18334; Rab6; dRab6; drab6; l(2)08323; rab6; wrt", "protein_names_uniprotkb": "Ras-related protein Rab6; Protein warthog", "protein_names_refseq": "CG6601-PB; Rab protein 6; Rab-protein 6; Rab6, isoform B; Rab6-PB; warthog", "tax_id": 7227, "disease": "retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (dme:Dmel_CG6601); (R-DME-6798695); (R-DME-6811436); (R-DME-6811438); (R-DME-6811440); (R-DME-8854214); (R-DME-8873719); (R-DME-8876198)", "pathway_count": 8, "publication_count": 24, "publication_id_list": "10459009;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17329360;17569856;17569867;17827179;18833296;19001129;21795785;21835342;22000105;22928698;25589440;26109356;26109357;33704067;9074639;9685396", "class_list": "", "function": "Protein transport (PubMed:17329360, PubMed:17827179, PubMed:18833296, PubMed:21835342, PubMed:22928698, PubMed:33704067, PubMed:9685396). Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) (PubMed:21795785). Mediates membrane trafficking during egg chamber growth and organization, possibly upstream of exocyst component Sec5. Also during oogenesis, plays a role, together with BicD but independently of Sec5, in the polarization of the oocyte microtubule cytoskeleton, in the localization of oskar mRNA and in the anterodorsal secretion of grk. Required for anterograde opsin transport through the ER-Golgi complex. Plays a role, together with Rich, in regulating CadN transport in photoreceptor cells which is required for the formation of normal synaptic connections between axons from the inner photoreceptor cells in the eye and postsynaptic cells in the brain medulla layer M6 (PubMed:21835342). Necessary for proper development of bristle shafts of macrochaete and microchaete on the head, thorax and scutellum. Modulates Notch signaling (PubMed:10459009). As a key regulator of vesicular traffic, plays a critical role in the regulation of actin organization and is required for normal rates of phagocytic uptake during phagocytosis involved in defense against viral and fungal infection., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0043025 neuronal cell body;GO:0043204 perikaryon", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0001881 receptor recycling;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "O18334-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O18373-1", "uniprot_id": [ { "id": "SPS1_DROME", "url": "https://www.uniprot.org/uniprot/O18373", "type": "external" } ], "mass": 43446.0, "length": 398, "protein_name": "Inactive selenide, water dikinase-like protein", "gene_name": "Sps1", "organism": "Fruit fly", "refseq_name": "selenophosphate synthetase 1, isoform A", "refseq_ac": [ { "id": "NP_725374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725374", "type": "external" } ], "gene_names_uniprotkb": "Sps1; CG8553; SelD; ptuf", "gene_names_refseq": "142926_at; CG8553; DSPS1; Dm SelD; Dm-SelD; Dmel\\CG8553; Dsps1; SPS1; SeS; SelD like; SelD; Sps1; anon-WO0172774.145; anon-WO0172774.146; dSPS1; dsps1; l(2)SH1599; l(2)SH2 1599; l(2)k12303; ptf1; ptuf1; ptuf; selD/sps1; selD", "protein_names_uniprotkb": "Inactive selenide, water dikinase-like protein; Protein patufet; Selenophosphate synthetase 1", "protein_names_refseq": "CG8553-PA; Selenide,water dikinase; Sps1-PA; lethal (2) SH1599; patufet; selD-like; selenophosphate synthetase 1, isoform A; selenophosphate synthetase 1", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal carcinoma (Disease Ontology:DOID:0080199)", "pathway": " (dme:Dmel_CG8553); (R-DME-2408557)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10444382;10731132;12527370;12537569;12537572;19755423;9398525;9491069", "class_list": "", "function": "Inactive selenophosphate synthetase-like protein not required for selenoprotein synthesis (PubMed:19755423, PubMed:9398525). Plays a role in apoptosis and consequently a role in imaginal disk patterning and growth (PubMed:10444382, PubMed:9491069). May be involved in response to oxidative stress (PubMed:12527370)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18597;Q0E979;Q9V700", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:2000378 negative regulation of reactive oxygen species metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "O18373-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O18405-1", "uniprot_id": [ { "id": "SURF4_DROME", "url": "https://www.uniprot.org/uniprot/O18405", "type": "external" } ], "mass": 30546.0, "length": 270, "protein_name": "Surfeit locus protein 4 homolog", "gene_name": "Surf4", "organism": "Fruit fly", "refseq_name": "surfeit 4", "refseq_ac": [ { "id": "NP_477222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477222", "type": "external" } ], "gene_names_uniprotkb": "Surf4; CG6202; Surf-4", "gene_names_refseq": "CG6202; Dmel\\CG6202; SURF-4; Surf-4; Surf4", "protein_names_uniprotkb": "Surfeit locus protein 4 homolog", "protein_names_refseq": "CG6202-PA; Surf4-PA; surfeit 4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6202); (R-DME-6798695); (R-DME-6811434)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8816471", "class_list": "", "function": "Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V2Y8;Q9VF84", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment;GO:0045169 fusome", "go_biological_process": "GO:0015031 protein transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O18405-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O44437-1", "uniprot_id": [ { "id": "SMD3_DROME", "url": "https://www.uniprot.org/uniprot/O44437", "type": "external" } ], "mass": 15582.0, "length": 151, "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "SmD3", "organism": "Fruit fly", "refseq_name": "small ribonucleoprotein particle protein SmD3", "refseq_ac": [ { "id": "NP_725106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725106", "type": "external" } ], "gene_names_uniprotkb": "SmD3; CG8427; guf2", "gene_names_refseq": "CG8427; Dmel\\CG8427; SYM10; Sm D3; SmD3; dD3; guf2; guf; l(2)131/7; l(2)154/1; l(2)90/37; smD3; smd3; snRNP Sm D3", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein Sm D3; Sm-D3; snRNP core protein D3", "protein_names_refseq": "CG8427-PA; SmD3-PA; gut feeling; gutfeeling; small ribonucleoprotein Sm D3; small ribonucleoprotein particle protein SmD3", "tax_id": 7227, "disease": "systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dme:Dmel_CG8427); (R-DME-111367); (R-DME-72163); (R-DME-72165); (R-DME-73856); (R-DME-77588); (R-DME-9770562); (R-DME-9943411)", "pathway_count": 8, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;18369183;18621711;9488472", "class_list": "", "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005829 cytosol;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP", "go_biological_process": "GO:0036261 7-methylguanosine cap hypermethylation;GO:0000278 mitotic cell cycle;GO:0007417 central nervous system development;GO:0007517 muscle organ development;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O44437-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O44783-1", "uniprot_id": [ { "id": "SPY_DROME", "url": "https://www.uniprot.org/uniprot/O44783", "type": "external" } ], "mass": 62389.0, "length": 589, "protein_name": "Protein sprouty", "gene_name": "sty", "organism": "Fruit fly", "refseq_name": "sprouty, isoform B", "refseq_ac": [ { "id": "NP_523902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523902", "type": "external" } ], "gene_names_uniprotkb": "sty; CG1921", "gene_names_refseq": "CG1921; CS3-3; Dmel\\CG1921; STY; Spry; Sry; Sty; dSPRY; spry; sty", "protein_names_uniprotkb": "Protein sprouty; Spry", "protein_names_refseq": "CG1921-PB; calcineurin suppressor, chromosome 3, group 3; dSprouty; sprouty, isoform B; sprouty; sty-PB", "tax_id": 7227, "disease": "ciliopathy (Disease Ontology:DOID:0060340); intestinal pseudo-obstruction (Disease Ontology:DOID:0080072); hypogonadotropic hypogonadism 17 with or without anosmia (Disease Ontology:DOID:0090079); IgA glomerulonephritis (Disease Ontology:DOID:2986); achalasia (Disease Ontology:DOID:9164)", "pathway": " (dme:Dmel_CG1921); (R-DME-1295596); (R-DME-182971)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10089881;10226010;10457022;10731132;12537572;9458049", "class_list": "", "function": "Inhibitor of tracheal branching that restricts branch budding by antagonizing the BNL-FGF pathway (BNL: branchless, an fgf inducer of branching). Acts as an antagonist of EGFR-mediated signaling in the eye (where it is important for cell determination) midline glia, chordotonal organs, wing and ovarian follicle cells., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1F3;Q6AWR4;Q9VZP7", "ec_number_list": [], "go_molecular_function": "GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045177 apical part of cell;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0046533 negative regulation of photoreceptor cell differentiation;GO:0046580 negative regulation of Ras protein signal transduction;GO:0021782 glial cell development;GO:0001666 response to hypoxia;GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O44783-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46040-1", "uniprot_id": [ { "id": "MSTAA_DROME", "url": "https://www.uniprot.org/uniprot/O46040", "type": "external" } ], "mass": 52157.0, "length": 462, "protein_name": "SET domain-containing protein SmydA-8, isoform A", "gene_name": "SmydA-8", "organism": "Fruit fly", "refseq_name": "SET and MYND domain containing, arthropod-specific, member 8, isoform A", "refseq_ac": [ { "id": "NP_001014717", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014717", "type": "external" } ], "gene_names_uniprotkb": "SmydA-8; CG18033; CG32799; CG32800; CG33548; Dmel\\CG33548; Dmel_CG33548; EG:103B4.4; EG:103B4.5; MSTA; Msta; msta", "gene_names_refseq": "CG18033; CG32799; CG32800; CG33548; Dmel\\CG33548; EG:103B4.4; EG:103B4.5; MSTA; Msta; SmydA-8; msta", "protein_names_uniprotkb": "SET domain-containing protein SmydA-8, isoform A; 2.1.1.-", "protein_names_refseq": "CG33548-PA; SET and MYND domain containing, arthropod-specific, member 8, isoform A; SmydA-8-PA; msta", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33548)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;10731137;10779958;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O46041;Q9UB82", "ec_number_list": [], "go_molecular_function": "GO:0042826 histone deacetylase binding;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity;GO:0008170 N-methyltransferase activity;GO:0008276 protein methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0010629 negative regulation of gene expression;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "O46040-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46077-1", "uniprot_id": [ { "id": "OR2A_DROME", "url": "https://www.uniprot.org/uniprot/O46077", "type": "external" } ], "mass": 45935.0, "length": 397, "protein_name": "Odorant receptor 2a", "gene_name": "Or2a", "organism": "Fruit fly", "refseq_name": "odorant receptor 2a", "refseq_ac": [ { "id": "NP_525046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_525046", "type": "external" } ], "gene_names_uniprotkb": "Or2a; AN4; CG3206; DOR2F.1; OR2F.1; dor62", "gene_names_refseq": "2F.1; 2a; AN4; CG3206; DOR2F.1; DOR62; Dmel\\CG3206; Dor62; EG:30B8.7; OR2a; Or2F.1; Or2a; Or62; dor62; or2a", "protein_names_uniprotkb": "Odorant receptor 2a", "protein_names_refseq": "CG3206-PA; Or2a-PA; odorant receptor 2a; odorant receptor 62; olfactory receptor 2F.1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3206)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10069338;10089887;10458908;10731132;10731137;10943836;12537572;16615896;21613503", "class_list": "", "function": "Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W504", "ec_number_list": [], "go_molecular_function": "GO:0004984 olfactory receptor activity;GO:0005549 odorant binding;GO:0170020 ionotropic olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0032590 dendrite membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007608 sensory perception of smell;GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "O46077-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46080-1", "uniprot_id": [ { "id": "SMG9_DROME", "url": "https://www.uniprot.org/uniprot/O46080", "type": "external" } ], "mass": 54727.0, "length": 487, "protein_name": "Protein SMG9", "gene_name": "CG3857", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_996330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996330", "type": "external" } ], "gene_names_uniprotkb": "CG3857", "gene_names_refseq": "CG3857; Dmel\\CG3857; EG:39E1.3", "protein_names_uniprotkb": "Protein SMG9; Protein smg-9 homolog", "protein_names_refseq": "CG3857-PA; uncharacterized protein", "tax_id": 7227, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG3857); (R-DME-975957)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;10731137;12537569;12537572;14709175", "class_list": "", "function": "Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0042332 gravitaxis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O46080-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46084-1", "uniprot_id": [ { "id": "PGAM5_DROME", "url": "https://www.uniprot.org/uniprot/O46084", "type": "external" } ], "mass": 33166.0, "length": 289, "protein_name": "Serine/threonine-protein phosphatase Pgam5, mitochondrial", "gene_name": "Pgam5", "organism": "Fruit fly", "refseq_name": "phosphoglycerate mutase 5, isoform A", "refseq_ac": [ { "id": "NP_569951", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569951", "type": "external" } ], "gene_names_uniprotkb": "Pgam5; CG14816; DPGAM5; Dmel\\CG14816; Dmel_CG14816; EG:63B12.4; PGAM5; dPGAM5; pgam5", "gene_names_refseq": "CG14816; DPGAM5; Dmel\\CG14816; EG:63B12.4; PGAM5; Pgam5; dPGAM5; pgam5", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase Pgam5, mitochondrial; 3.1.3.16; DPGAM5; Phosphoglycerate mutase family member 5 homolog", "protein_names_refseq": "CG14816-PA; Pgam5-PA; phosphoglycerate mutase 5, isoform A; phosphoglycerate mutase 5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14816); (R-DME-8934903); (R-DME-9861718)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;19590015;25589440;26109356;26109357", "class_list": "", "function": "Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase. Has apparently no phosphoglycerate mutase activity., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7K2X2", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0016020 membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0010636 positive regulation of mitochondrial fusion;GO:0009408 response to heat;GO:0010821 regulation of mitochondrion organization;GO:0090141 positive regulation of mitochondrial fission;GO:0072347 response to anesthetic", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "O46084-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46102-1", "uniprot_id": [ { "id": "PAPD1_DROME", "url": "https://www.uniprot.org/uniprot/O46102", "type": "external" } ], "mass": 68546.0, "length": 612, "protein_name": "Poly(A) RNA polymerase, mitochondrial", "gene_name": "MTPAP", "organism": "Fruit fly", "refseq_name": "mitochondrial poly(A) polymerase, isoform C", "refseq_ac": [ { "id": "NP_001259129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259129", "type": "external" } ], "gene_names_uniprotkb": "MTPAP; CG11418; DmMTPAP; DmNP_569904; Dmel\\CG11418; Dmel_CG11418; EG:8D8.8; SD27341p; TUTase1; dmmtpap", "gene_names_refseq": "CG11418; DmMTPAP; DmNP_569904; Dmel\\CG11418; EG:8D8.8; MTPAP; SD27341p; TUTase1; dmmtpap", "protein_names_uniprotkb": "Poly(A) RNA polymerase, mitochondrial; 2.7.7.19; DmMTPAP", "protein_names_refseq": "3' terminal uridylyl transferase 1; CG11418-PC; MTPAP-PC; mitochondrial poly(A) polymerase, isoform C", "tax_id": 7227, "disease": "spastic ataxia 4 (Disease Ontology:DOID:0050943)", "pathway": " (dme:Dmel_CG11418)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;27176048", "class_list": "", "function": "Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. This is not required for transcript stability or translation but may maintain mRNA integrity by protecting 3' termini from degradation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O46103;Q8MRT1", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0097222 mitochondrial mRNA polyadenylation;GO:0031123 RNA 3'-end processing;GO:0036416 tRNA stabilization;GO:0090616 mitochondrial mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "O46102-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O46107-1", "uniprot_id": [ { "id": "LIP1_DROME", "url": "https://www.uniprot.org/uniprot/O46107", "type": "external" } ], "mass": 50661.0, "length": 439, "protein_name": "Lipase 1", "gene_name": "Lip1", "organism": "Fruit fly", "refseq_name": "lipase 1, isoform B", "refseq_ac": [ { "id": "NP_001285811", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285811", "type": "external" } ], "gene_names_uniprotkb": "Lip1; CG7279; Dmel\\CG7279; Dmel_CG7279; Dmlip1; LIP1Dm; Lip; dLip1; lip1", "gene_names_refseq": "CG7279; Dmel\\CG7279; Dmlip1; LIP1Dm; Lip1; Lip; dLip1; lip1", "protein_names_uniprotkb": "Lipase 1; 3.1.1.-; DmLip1", "protein_names_refseq": "CG7279-PB; Lip1-PB; Lipase1; lipase 1, isoform B; lipase 1", "tax_id": 7227, "disease": "lysosomal acid lipase deficiency (Disease Ontology:DOID:0080217); Wolman disease (Disease Ontology:DOID:14497)", "pathway": " (dme:Dmel_CG7279); (R-DME-192456); (R-DME-6809371)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9566193", "class_list": "", "function": "Could be a digestive enzyme., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q9VKR6", "ec_number_list": [ { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0016298 lipase activity;GO:0004806 triacylglycerol lipase activity;GO:0016788 hydrolase activity, acting on ester bonds", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0016042 lipid catabolic process;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "O46107-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O61345-1", "uniprot_id": [ { "id": "PENG_DROME", "url": "https://www.uniprot.org/uniprot/O61345", "type": "external" } ], "mass": 81302.0, "length": 737, "protein_name": "Protein penguin", "gene_name": "peng", "organism": "Fruit fly", "refseq_name": "penguin", "refseq_ac": [ { "id": "NP_523429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523429", "type": "external" } ], "gene_names_uniprotkb": "peng; CG1685; pen", "gene_names_refseq": "CG1685; Dmel\\CG1685; peng; pen", "protein_names_uniprotkb": "Protein penguin", "protein_names_refseq": "CG1685-PA; peng-PA; penguin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1685)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;10731138;12537572;9520435", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VRH2", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0006417 regulation of translation;GO:0007475 apposition of dorsal and ventral imaginal disc-derived wing surfaces", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O61345-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O61613-1", "uniprot_id": [ { "id": "NMT_DROME", "url": "https://www.uniprot.org/uniprot/O61613", "type": "external" } ], "mass": 53833.0, "length": 472, "protein_name": "Glycylpeptide N-tetradecanoyltransferase", "gene_name": "Nmt", "organism": "Fruit fly", "refseq_name": "N-myristoyl transferase", "refseq_ac": [ { "id": "NP_523969", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523969", "type": "external" } ], "gene_names_uniprotkb": "Nmt; CG7436", "gene_names_refseq": "153290_at; CG7436; Dmel\\CG7436; Nmt1; Nmt; dNMT; l(3)j1C7; l(3)j1c7; nmt", "protein_names_uniprotkb": "Glycylpeptide N-tetradecanoyltransferase; 2.3.1.97; Myristoyl-CoA:protein N-myristoyltransferase; NMT; Peptide N-myristoyltransferase; dNMT", "protein_names_refseq": "CG7436-PA; N-myristoyl transferase; Nmt-PA", "tax_id": 7227, "disease": "muscular disease (Disease Ontology:DOID:0080000)", "pathway": " (dme:Dmel_CG7436)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10731138;11139338;12537569;12537572;9044045", "class_list": "", "function": "Adds a myristoyl group (tetradecanoyl group) to the N-terminal glycine residue of certain cellular proteins (Probable). Such protein modification are critical for the developmental processes that involve cell shape changes and movement (PubMed:11139338)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9XZ55", "ec_number_list": [ { "id": "2.3.1.97", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.97", "type": "external" } ], "go_molecular_function": "GO:0004379 glycylpeptide N-tetradecanoyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0072657 protein localization to membrane;GO:0007391 dorsal closure", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O61613-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O76511-1", "uniprot_id": [ { "id": "TYSY_DROME", "url": "https://www.uniprot.org/uniprot/O76511", "type": "external" } ], "mass": 36657.0, "length": 321, "protein_name": "Thymidylate synthase", "gene_name": "Ts", "organism": "Fruit fly", "refseq_name": "thymidylate synthase, isoform B", "refseq_ac": [ { "id": "NP_001285570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285570", "type": "external" } ], "gene_names_uniprotkb": "Ts; CG3181", "gene_names_refseq": "CG3181; Dmel\\CG3181; FBgn0024920; TS; Ts; anon-23Ca; c1.5", "protein_names_uniprotkb": "Thymidylate synthase; 2.1.1.45; TSase; TS", "protein_names_refseq": "CG3181-PB; Ts-PB; thymidilate synthetase; thymidylate synthase, isoform B", "tax_id": 7227, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); digenic dyskeratosis congenita (Disease Ontology:DOID:0060984); urinary bladder cancer (Disease Ontology:DOID:11054); colon carcinoma (Disease Ontology:DOID:1520); cancer (Disease Ontology:DOID:162); cerebral infarction (Disease Ontology:DOID:3526); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); abdominal aortic aneurysm (Disease Ontology:DOID:7693); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG3181); (R-DME-499943)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537572;15952742;17372656;18327897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQJ3", "ec_number_list": [ { "id": "2.1.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.45", "type": "external" } ], "go_molecular_function": "GO:0004799 thymidylate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005829 cytosol", "go_biological_process": "GO:0006231 dTMP biosynthetic process;GO:0032259 methylation;GO:0006235 dTTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "O76511-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O76932-1", "uniprot_id": [ { "id": "PP4C_DROME", "url": "https://www.uniprot.org/uniprot/O76932", "type": "external" } ], "mass": 35341.0, "length": 307, "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "Pp4-19C", "organism": "Fruit fly", "refseq_name": "protein phosphatase 19C, isoform H", "refseq_ac": [ { "id": "NP_001285489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285489", "type": "external" } ], "gene_names_uniprotkb": "Pp4-19C; CG1459; CG1596; CG18339; CG32505; DmPpp4-19C; Dmel\\CG32505; Dmel_CG32505; PP1; PP4 19C; PP4-19C; PP4-19c; PP4-1; PP4C; PP4c; PP4; PPP4c; PPX; Pp4-19c; PpX; Ppp4c; dPP4; pp4", "gene_names_refseq": "CG1459; CG1596; CG18339; CG32505; DmPpp4-19C; Dmel\\CG32505; PP1; PP4 19C; PP4-19C; PP4-19c; PP4-1; PP4C; PP4c; PP4; PPP4c; PPX; Pp4-19C; Pp4-19c; PpX; Ppp4c; dPP4; pp4", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 4 catalytic subunit; 3.1.3.16; PP4C", "protein_names_refseq": "CG32505-PH; Pp4-19C-PH; phosphoprotein phosphatase 4; protein phosphatase 19C, isoform H; protein phosphatase 1; protein phosphatase 4; protein phosphatase X", "tax_id": 7227, "disease": "oligoasthenoteratozoospermia (Disease Ontology:DOID:0070311); chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515)", "pathway": " (dme:Dmel_CG32505)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18487071;25589440;26109356;26109357;26586222;9570751", "class_list": "", "function": "Protein phosphatase that regulates many processes such as microtubule organization at centrosomes. The probable PP4 complex Pp4-19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase-induced cell death (in vitro)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VR98", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0000775 chromosome, centromeric region;GO:0030289 protein phosphatase 4 complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007346 regulation of mitotic cell cycle;GO:0000724 double-strand break repair via homologous recombination;GO:0045879 negative regulation of smoothened signaling pathway;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "O76932-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O77059-1", "uniprot_id": [ { "id": "CRY1_DROME", "url": "https://www.uniprot.org/uniprot/O77059", "type": "external" } ], "mass": 62513.0, "length": 542, "protein_name": "Cryptochrome-1", "gene_name": "cry", "organism": "Fruit fly", "refseq_name": "cryptochrome", "refseq_ac": [ { "id": "NP_732407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_732407", "type": "external" } ], "gene_names_uniprotkb": "cry; CG3772", "gene_names_refseq": "CG3772; CRYPTOCHROME; CRY; Cry; DCry; Dm-CRY1; DmCRY1; DmCRY; DmCry1; DmCry; Dmcry; Dmel\\CG3772; anon-WO0140519.17; anon-WO0140519.19; anon-WO0140519.20; anon-WO0172774.15; cry1; cryb; cry; dCRY; dCry; dcry", "protein_names_uniprotkb": "Cryptochrome-1; Blue light photoreceptor; DmCRY1; dcry", "protein_names_refseq": "Blue-light receptor; CG3772-PA; cry-PA; crybaby; crypochrome; cryptochrome", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3772); (R-DME-432395); (R-DME-432553); (R-DME-538864)", "pathway_count": 4, "publication_count": 43, "publication_id_list": "10063806;10233998;10417378;10481010;10731132;11430804;11440719;11448767;11585911;12122057;12432393;12442174;12447397;12537569;12537572;12563262;12944510;14759367;15178801;15258584;16319317;16410523;16527739;16794082;17298948;17418796;18519643;18593878;18597555;18641630;18815259;19185492;23518567;23746849;26569474;36994075;7481773;8596938;8600384;8938123;9674431;9845369;9845370", "class_list": "", "function": "Blue light-dependent regulator that is the input of the circadian feedback loop (PubMed:10063806, PubMed:10233998, PubMed:10417378, PubMed:16527739, PubMed:17298948, PubMed:18597555, PubMed:36994075, PubMed:9845369). Has no photolyase activity for cyclobutane pyrimidine dimers or 6-4 photoproducts (PubMed:10063806). Regulation of expression by light suggests a role in photoreception for locomotor activity rhythms (PubMed:10063806, PubMed:10233998, PubMed:9845369). Functions, together with per, as a transcriptional repressor required for the oscillation of peripheral circadian clocks and for the correct specification of clock cells (PubMed:10417378, PubMed:16527739, PubMed:36994075, PubMed:9845370). Genes directly activated by the transcription factors Clock (Clk) and cycle (cyc) are repressed by cry (PubMed:10417378, PubMed:16527739). Necessary for light-dependent magnetosensitivity, an intact circadian system is not required for the magnetoreception mechanism to operate (PubMed:18641630). Required for both the naive and trained responses to magnetic field, consistent with the notion that cry is in the input pathway of magnetic sensing (PubMed:18641630)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9TYA0", "ec_number_list": [], "go_molecular_function": "GO:0009882 blue light photoreceptor activity;GO:0003677 DNA binding;GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0009881 photoreceptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0009785 blue light signaling pathway;GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 4.4, "record_id": "O77059-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O77263-1", "uniprot_id": [ { "id": "TRMB_DROME", "url": "https://www.uniprot.org/uniprot/O77263", "type": "external" } ], "mass": 29425.0, "length": 256, "protein_name": "tRNA (guanine-N(7)-)-methyltransferase", "gene_name": "Mettl1", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_569978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569978", "type": "external" } ], "gene_names_uniprotkb": "Mettl1; CG4045", "gene_names_refseq": "CG4045; Dmel\\CG4045; EG:22E5.4; METTL1", "protein_names_uniprotkb": "tRNA (guanine-N(7)-)-methyltransferase; 2.1.1.33; tRNA (guanine(46)-N(7))-methyltransferase; tRNA methylguanosine methyltransferase 1; tRNA(m7G46)-methyltransferase", "protein_names_refseq": "CG4045-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4045)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;10731137;12537569;12537572;39317727", "class_list": "", "function": "Catalytic component of Mettl1-wuho methyltransferase complex that mediates the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) (PubMed:39317727). Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in a subset of tRNAs that contain the 5'-RAGGU-3' motif within the variable loop (By similarity) (PubMed:39317727). M7G46 interacts with C13-G22 in the D-loop to stabilize tRNA tertiary structure and protect tRNAs from decay (By similarity). Required for the elongation step of spermatid formation (PubMed:39317727)., [UniProtKB, HAMAP, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W527", "ec_number_list": [ { "id": "2.1.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.33", "type": "external" } ], "go_molecular_function": "GO:0000049 tRNA binding;GO:0008176 tRNA (guanine(46)-N7)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0043527 tRNA methyltransferase complex;GO:0106143 tRNA (m7G46) methyltransferase complex", "go_biological_process": "GO:0036265 RNA (guanine-N7)-methylation;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0006400 tRNA modification;GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O77263-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O77430-1", "uniprot_id": [ { "id": "O77430_DROME", "url": "https://www.uniprot.org/uniprot/O77430", "type": "external" } ], "mass": 18597.0, "length": 162, "protein_name": "SKP1-related A, isoform A; SKP1-related A, isoform B; SKP1-related A, isoform C; SKP1-related A, isoform D; SKP1-related A, isoform E; SKP1-related A, isoform F; SKP1-related A, isoform G; SKP1-related A, isoform H; SKP1-related A, isoform I", "gene_name": "SkpA", "organism": "Fruit fly", "refseq_name": "SKP1-related A, isoform H", "refseq_ac": [ { "id": "NP_001033818", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033818", "type": "external" } ], "gene_names_uniprotkb": "SkpA; CG16983; Dmel\\CG16983; Dmel_CG16983; EG:115C2.4; SKP1; SKPA; Skp1; Skp; anon-WO03040301.234; anon-WO03040301.236; anon-WO03040301.238; dSKP1; dSkip-1; dSkp-1; dSkpA; dskpA; l(1)G0037; l(1)G0058; l(1)G0109; l(1)G0389; skpA; spkA", "gene_names_refseq": "CG16983; Dmel\\CG16983; EG:115C2.4; SKP1; SKPA; Skp1; SkpA; Skp; anon-WO03040301.234; anon-WO03040301.236; anon-WO03040301.238; dSKP1; dSkip-1; dSkp-1; dSkpA; dskpA; l(1)G0037; l(1)G0058; l(1)G0109; l(1)G0389; skpA; spkA", "protein_names_uniprotkb": "SKP1-related A, isoform A; SKP1-related A, isoform B; SKP1-related A, isoform C; SKP1-related A, isoform D; SKP1-related A, isoform E; SKP1-related A, isoform F; SKP1-related A, isoform G; SKP1-related A, isoform H; SKP1-related A, isoform I", "protein_names_refseq": "CG16983-PH; SCF-betaTrCP complex; SKP1-related A, isoform H; Skp1-related gene A; SkpA-PH; skpA", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG16983); (R-DME-1169091); (R-DME-174113); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209461); (R-DME-2565942); (R-DME-2871837); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5676590); (R-DME-68949); (R-DME-69231); (R-DME-69601); (R-DME-8854050); (R-DME-8939902); (R-DME-8951664); (R-DME-9020702); (R-DME-917937); (R-DME-9762114); (R-DME-983168)", "pathway_count": 25, "publication_count": 19, "publication_id_list": "10102270;10458606;10731132;12231619;12537568;12537572;12537573;12537574;16110336;16299518;16326393;16386907;17569856;17569867;17925225;25589440;26109356;26109357;9215627", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0097602 cullin family protein binding;GO:0160072 ubiquitin ligase complex scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0000278 mitotic cell cycle;GO:0016322 neuron remodeling;GO:0043066 negative regulation of apoptotic process;GO:0045931 positive regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "O77430-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O96838-1", "uniprot_id": [ { "id": "FYV1_DROME", "url": "https://www.uniprot.org/uniprot/O96838", "type": "external" } ], "mass": 204635.0, "length": 1809, "protein_name": "Putative 1-phosphatidylinositol 3-phosphate 5-kinase", "gene_name": "fab1", "organism": "Fruit fly", "refseq_name": "fab1 kinase, isoform A", "refseq_ac": [ { "id": "NP_611269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611269", "type": "external" } ], "gene_names_uniprotkb": "fab1; CG6355", "gene_names_refseq": "CG6355; Dmel\\CG6355; EG:52C10.5; Fab1; PI3P5K; PIKfyve; PtdIns3P; fab-1; fab1; l(2)SJB", "protein_names_uniprotkb": "Putative 1-phosphatidylinositol 3-phosphate 5-kinase; 2.7.1.150; PIPkin-III; Phosphatidylinositol 3-phosphate 5-kinase; Type III PIP kinase", "protein_names_refseq": "CG6355-PA; PtdIns(3)P 5-kinase; fab1 kinase, isoform A; fab1-PA", "tax_id": 7227, "disease": "Fleck corneal dystrophy (Disease Ontology:DOID:0060448); cataract (Disease Ontology:DOID:83); Crohn's disease (Disease Ontology:DOID:8778)", "pathway": " (dme:Dmel_CG6355)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10731137;12537569;12537572;16837550;18327897", "class_list": "", "function": "Regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) or PtdIns(3,5)P2) (PubMed:16837550). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)) on the fifth hydroxyl of the myo-inositol ring, to form PtdIns(3,5)P2 (PubMed:16837550). Required for endocytic-vacuolar pathway and nuclear migration. Has a role at a late stage in endosome-related membrane trafficking, at a point when signal termination has occurred. Is not required for receptor silencing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZM3;Q8SZX0;Q95SX9;Q9V886", "ec_number_list": [ { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" } ], "go_molecular_function": "GO:0052810 1-phosphatidylinositol-5-kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity", "go_cellular_component": "GO:0005768 endosome;GO:0010008 endosome membrane;GO:0012506 vesicle membrane;GO:0070772 PAS complex", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0035556 intracellular signal transduction;GO:0008333 endosome to lysosome transport;GO:0007033 vacuole organization;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O96838-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O97183-1", "uniprot_id": [ { "id": "O97183_DROME", "url": "https://www.uniprot.org/uniprot/O97183", "type": "external" } ], "mass": 31243.0, "length": 275, "protein_name": "DNA-directed RNA polymerase II subunit RPB3", "gene_name": "Polr2C", "organism": "Fruit fly", "refseq_name": "RNA polymerase II subunit C", "refseq_ac": [ { "id": "NP_477419", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477419", "type": "external" } ], "gene_names_uniprotkb": "Polr2C; 152117_at; BG:DS00941.10; CG7885; D-rpII33; Dmel\\CG7885; Dmel_CG7885; Pol II RPII33; Pol II; PolIIo; PolII; RNA Pol II; RNA pol II; RNA polII; RNAP; RPB3; Rbp3; RpII33; Rpb3; Rpll33; br17; l(2)34Dg; l(2)br17; l(2)k05605; l34Dg; pol II; polII; rpII33; rpb3", "gene_names_refseq": "152117_at; BG:DS00941.10; CG7885; D-rpII33; Dmel\\CG7885; Pol II RPII33; Pol II; PolIIo; PolII; Polr2C; RNA Pol II; RNA pol II; RNA polII; RNAP; RPB3; Rbp3; RpII33; Rpb3; Rpll33; br17; l(2)34Dg; l(2)br17; l(2)k05605; l34Dg; pol II; polII; rpII33; rpb3", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB3", "protein_names_refseq": "CG7885-PA; Polr2C-PA; RNA polymerase II 33kD subunit; RNA polymerase II subunit 3; RNA polymerase II subunit C; lethal 17 in the black-reduced region; lethal(2)34Dg", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7885); (R-DME-112382); (R-DME-113418); (R-DME-5578749); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-6807505); (R-DME-72086); (R-DME-72163); (R-DME-72165); (R-DME-72203); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075); (R-DME-9018519); (R-DME-9770562)", "pathway_count": 22, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0046983 protein dimerization activity;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005665 RNA polymerase II, core complex;GO:0005700 polytene chromosome;GO:0005703 polytene chromosome puff", "go_biological_process": "GO:0034605 cellular response to heat;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "O97183-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P02255-1", "uniprot_id": [ { "id": "H1_DROME", "url": "https://www.uniprot.org/uniprot/P02255", "type": "external" } ], "mass": 26359.0, "length": 256, "protein_name": "Histone H1", "gene_name": "His1:CG31617; His1:CG33804; His1:CG33810; His1:CG33813; His1:CG33816; His1:CG33819; His1:CG33822; His1:CG33825; His1:CG33828; His1:CG33831; His1:CG33837; His1:CG33840; His1:CG33843; His1:CG33846; His1:CG33849; His1:CG33852; His1:CG33864; His1", "organism": "Fruit fly", "refseq_name": "histone H1", "refseq_ac": [ { "id": "NP_001027286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027286", "type": "external" } ], "gene_names_uniprotkb": "His1:CG31617; His1:CG33804; His1:CG33810; His1:CG33813; His1:CG33816; His1:CG33819; His1:CG33822; His1:CG33825; His1:CG33828; His1:CG33831; His1:CG33837; His1:CG33840; His1:CG33843; His1:CG33846; His1:CG33849; His1:CG33852; His1:CG33864; His1; CG31617; CG33804; CG33810; CG33813; CG33816; CG33819; CG33822; CG33825; CG33828; CG33831; CG33837; CG33840; CG33843; CG33846; CG33849; CG33852; CG33864", "gene_names_refseq": "CG33804; Dmel\\CG33804; His1:CG33804", "protein_names_uniprotkb": "Histone H1", "protein_names_refseq": "CG33804-PA; His1:CG33804-PA; histone H1", "tax_id": 7227, "disease": "acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG31617); (dme:Dmel_CG33804); (dme:Dmel_CG33810); (dme:Dmel_CG33813); (dme:Dmel_CG33816); (dme:Dmel_CG33819); (dme:Dmel_CG33822); (dme:Dmel_CG33825); (dme:Dmel_CG33828); (dme:Dmel_CG33831); (dme:Dmel_CG33837); (dme:Dmel_CG33840); (dme:Dmel_CG33843); (dme:Dmel_CG33846); (dme:Dmel_CG33849); (dme:Dmel_CG33852); (dme:Dmel_CG33864)", "pathway_count": 17, "publication_count": 11, "publication_id_list": "10731132;12537572;1311255;16230526;17372656;17827147;1899487;2536150;3090518;31028139;37268618", "class_list": "", "function": "Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q4ABD3", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031490 chromatin DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000786 nucleosome", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination;GO:0031507 heterochromatin formation;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P02255-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P02835-1", "uniprot_id": [ { "id": "FTZ_DROME", "url": "https://www.uniprot.org/uniprot/P02835", "type": "external" } ], "mass": 46479.0, "length": 410, "protein_name": "Segmentation protein fushi tarazu", "gene_name": "ftz", "organism": "Fruit fly", "refseq_name": "fushi tarazu", "refseq_ac": [ { "id": "NP_477498", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477498", "type": "external" } ], "gene_names_uniprotkb": "ftz; CG2047", "gene_names_refseq": "BG:DS07876.1; CG2047; Dm-Ftz; Dm-ftz; DmFtz; Dmel\\CG2047; Dmftz; FTZ; Ftz; Ual; ftz; l(3)84Ag", "protein_names_uniprotkb": "Segmentation protein fushi tarazu", "protein_names_refseq": "CG2047-PA; Fushi-Tarazu; Ultra-abdominal-like; ftz-PA; fushi tarazu; fushitarazu", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2047)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10731132;12537572;2276626;2743978;2892267;3049237;6327065;6330566;6330741;7909851", "class_list": "", "function": "May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "O96929;Q4V6Y3;Q9V3W3", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001708 cell fate specification;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P02835-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P02840-1", "uniprot_id": [ { "id": "SGS3_DROME", "url": "https://www.uniprot.org/uniprot/P02840", "type": "external" } ], "mass": 32196.0, "length": 307, "protein_name": "Salivary glue protein Sgs-3", "gene_name": "Sgs3", "organism": "Fruit fly", "refseq_name": "salivary gland secretion 3", "refseq_ac": [ { "id": "NP_524024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524024", "type": "external" } ], "gene_names_uniprotkb": "Sgs3; CG11720", "gene_names_refseq": "68C GII; CG11720; DMSGS378; Dmel\\CG11720; Glue; Muc68Cb; SGS-3; SGS378; Sgs-3; Sgs3; Sgs; sgs-3; sgs3", "protein_names_uniprotkb": "Salivary glue protein Sgs-3", "protein_names_refseq": "CG11720-PA; Sgs3-PA; gene IV; group IV; mucin 68Cb; salivary gland glue protein 3; salivary gland secretion 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11720)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537572;30158631;3138416;6411930;8223281", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VTJ2", "ec_number_list": [], "go_molecular_function": "GO:0140073 bioadhesive activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007594 puparial adhesion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P02840-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P02841-1", "uniprot_id": [ { "id": "SGS7_DROME", "url": "https://www.uniprot.org/uniprot/P02841", "type": "external" } ], "mass": 7920.0, "length": 74, "protein_name": "Salivary glue protein Sgs-7", "gene_name": "Sgs7", "organism": "Fruit fly", "refseq_name": "salivary gland secretion 7", "refseq_ac": [ { "id": "NP_476718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476718", "type": "external" } ], "gene_names_uniprotkb": "Sgs7; CG18087", "gene_names_refseq": "68C GIII; CG18087; Dmel\\CG18087; Sgs-7; Sgs7; sgs-7; sgs7", "protein_names_uniprotkb": "Salivary glue protein Sgs-7", "protein_names_refseq": "CG18087-PA; Sgs7-PA; gene III; group III; salivary gland secretion 7", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18087)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;6411930", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VTJ0", "ec_number_list": [], "go_molecular_function": "GO:0140073 bioadhesive activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007594 puparial adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P02841-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P02842-1", "uniprot_id": [ { "id": "SGS8_DROME", "url": "https://www.uniprot.org/uniprot/P02842", "type": "external" } ], "mass": 7918.0, "length": 75, "protein_name": "Salivary glue protein Sgs-8", "gene_name": "Sgs8", "organism": "Fruit fly", "refseq_name": "salivary gland secretion 8", "refseq_ac": [ { "id": "NP_476719", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476719", "type": "external" } ], "gene_names_uniprotkb": "Sgs8; CG6132", "gene_names_refseq": "68C GII; CG6132; Dmel\\CG6132; Sgs-8; Sgs8; Sgs; sgs-8; sgs8", "protein_names_uniprotkb": "Salivary glue protein Sgs-8", "protein_names_refseq": "CG6132-PA; Sgs8-PA; gene II; group II; salivary gland secretion 8", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6132)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;6411930", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VTI9", "ec_number_list": [], "go_molecular_function": "GO:0140073 bioadhesive activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007594 puparial adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P02842-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P04052-1", "uniprot_id": [ { "id": "RPB1_DROME", "url": "https://www.uniprot.org/uniprot/P04052", "type": "external" } ], "mass": 209168.0, "length": 1887, "protein_name": "DNA-directed RNA polymerase II subunit RPB1", "gene_name": "Polr2A", "organism": "Fruit fly", "refseq_name": "RNA polymerase II subunit A", "refseq_ac": [ { "id": "NP_511124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_511124", "type": "external" } ], "gene_names_uniprotkb": "Polr2A; CG1554; RPB1; RpII215", "gene_names_refseq": "5; 8WG16; CG1554; CTD; DmCTD; Dmel\\CG1554; H5; IIo; II; L5; POL; Pol II CTD; Pol II Ser5P; Pol II Ser5p; Pol II0[ser2]; Pol II0[ser5]; Pol II[ser2]; Pol IIa; Pol IIo[Ser2]; Pol IIo[ser2]; Pol IIo[ser5]; Pol IIo; Pol II; Pol-IIa; Pol-II; PolIIa; PolIIo[ser2]; PolIIo[ser5]; PolIIo; PolII; PolR2A; Poll II; Polr2A; RNA Pol II CTD; RNA Pol II ser2P; RNA Pol II; RNA PolI 215; RNA PolII CTD; RNA PolII; RNA pol IIo; RNA pol II; RNA polII; RNA-PolII; RNA-Pol; RNAP II LS; RNAP II; RNAPII Ser5P; RNAPII0; RNAPII[[0]][ser5]; RNAPII; RNAPoIIII; RNAP; RNApol II; RNApol2; RNApolII; RNApol; RPB1; RPII215; RPO21; RpII215; RpII; Rpb1; Rpll215; Ser5-P Pol II; Ubl; alphaPol IIo[ser2]; dRPB1; dRpb1; l(1)10Ca; l(1)DC912; l(1)DF912; l(1)G0040; l(1)L5; pol II; polII; rpII1", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB1; 2.7.7.6; DNA-directed RNA polymerase III largest subunit; RNA polymerase II subunit A; RNA polymerase II subunit B1", "protein_names_refseq": "CG1554-PA; Pol II CTD; Pol II large subunit CTD; Polr2A-PA; RNA Pol II; RNA polymerase II 215kD subunit; RNA polymerase II large subunit; RNA polymerase II largest subunit; RNA polymerase II subunit A; RNA polymerase IIo; RNA polymeraseII-215 kd subunit; RNA-polymerase II; Ultrabithorax-like; polymerase II CTD", "tax_id": 7227, "disease": "Cockayne syndrome (Disease Ontology:DOID:2962); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (dme:Dmel_CG1554); (R-DME-112382); (R-DME-113418); (R-DME-5578749); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-6807505); (R-DME-72086); (R-DME-72163); (R-DME-72165); (R-DME-72203); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075); (R-DME-9018519); (R-DME-9770562)", "pathway_count": 22, "publication_count": 22, "publication_id_list": "10731132;12537572;18070927;18200011;18575576;18846226;21135120;23173091;2496296;25679530;2992806;3025586;30356106;31091233;3122024;32029739;32697989;33277495;33410907;33925313;8552047;9328567", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9VYX6", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "2.1.1.348", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.348", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.1.1.56", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.56", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005665 RNA polymerase II, core complex;GO:0005700 polytene chromosome;GO:0005703 polytene chromosome puff", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0042789 mRNA transcription by RNA polymerase II;GO:0006369 termination of RNA polymerase II transcription", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P04052-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P04359-1", "uniprot_id": [ { "id": "RL32_DROME", "url": "https://www.uniprot.org/uniprot/P04359", "type": "external" } ], "mass": 16020.0, "length": 134, "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "RpL32", "organism": "Fruit fly", "refseq_name": "ribosomal protein L32, isoform D", "refseq_ac": [ { "id": "NP_001138127", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138127", "type": "external" } ], "gene_names_uniprotkb": "RpL32; CG7939; M(3)99D; rp49", "gene_names_refseq": "143250_at; BcDNA:RH03940; CG7939; Dmel\\CG7939; L32e; L32; M(3)99D; RP-49; RP49; RPL32; Rp-49; Rp49/RpL32; Rp49; RpL32; Rpl32; bs30a02.y1; rp49/RpL32; rp49; rpl32", "protein_names_uniprotkb": "Large ribosomal subunit protein eL32; 60S ribosomal protein L32; Ribosomal protein 49", "protein_names_refseq": "CG7939-PD; Minute(3)99D; RpL32-PD; r-protein 49; ribosomal protein 49/L32; ribosomal protein L32, isoform D; ribosomal protein L32", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7939); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;23636399;6087289;9479691", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V3M7;B7Z0S1;O01386;Q8IMJ6;Q9VAB2", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P04359-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P04388-1", "uniprot_id": [ { "id": "RAS2_DROME", "url": "https://www.uniprot.org/uniprot/P04388", "type": "external" } ], "mass": 22236.0, "length": 192, "protein_name": "Ras-like protein 2", "gene_name": "Ras64B", "organism": "Fruit fly", "refseq_name": "Ras oncogene at 64B", "refseq_ac": [ { "id": "NP_523917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523917", "type": "external" } ], "gene_names_uniprotkb": "Ras64B; CG1167; ras2", "gene_names_refseq": "BcDNA:RE36103; C-ras2; CG1167; D-ras-2; D-ras2; DRas2; Dm-ras-64B; Dmel\\CG1167; Dmras64B; Dras2; Dras64B; RAS2; RAS64B; RAS; Ras2; Ras64B; Ras; c-ras2; ras-2; ras2; ras", "protein_names_uniprotkb": "Ras-like protein 2; 3.6.5.2", "protein_names_refseq": "CG1167-PA; Ras oncogene at 64B; Ras64B-PA; ras oncogene; small GTP binding protein", "tax_id": 7227, "disease": "Costello syndrome (Disease Ontology:DOID:0050469); RASopathy (Disease Ontology:DOID:0080690); Noonan syndrome 12 (Disease Ontology:DOID:0112170); urinary bladder cancer (Disease Ontology:DOID:11054)", "pathway": " (dme:Dmel_CG1167)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10552039;10731132;12537569;12537572;2838380;30735487;3110012;31491385;3412773;3921827;6430564;7789770;8404533", "class_list": "", "function": "May be involved in endocytic processes and/or other transport pathways mediated by vesicle trafficking. May interact functionally with ROP protein. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VZH7", "ec_number_list": [ { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P04388-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P04950-1", "uniprot_id": [ { "id": "OPS3_DROME", "url": "https://www.uniprot.org/uniprot/P04950", "type": "external" } ], "mass": 42940.0, "length": 383, "protein_name": "Opsin Rh3", "gene_name": "Rh3", "organism": "Fruit fly", "refseq_name": "rhodopsin 3", "refseq_ac": [ { "id": "NP_524411", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524411", "type": "external" } ], "gene_names_uniprotkb": "Rh3; CG10888; RH92CD", "gene_names_refseq": "CG10888; DMELRH3; Dm Rh3; Dmel\\CG10888; RH3; Rh3; Rh; r3; rh3", "protein_names_uniprotkb": "Opsin Rh3; Inner R7 photoreceptor cells opsin", "protein_names_refseq": "CG10888-PA; Rh3-PA; Rhodopsin3; rhodopsin 3; rhodopsin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10888)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10731138;12537572;2437266;2953598;8006992", "class_list": "", "function": "Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9TX53", "ec_number_list": [], "go_molecular_function": "GO:0008020 G protein-coupled photoreceptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007601 visual perception;GO:0007602 phototransduction;GO:0071482 cellular response to light stimulus;GO:0009589 detection of UV", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P04950-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P05205-1", "uniprot_id": [ { "id": "HP1_DROME", "url": "https://www.uniprot.org/uniprot/P05205", "type": "external" } ], "mass": 23185.0, "length": 206, "protein_name": "Heterochromatin protein 1", "gene_name": "Su(var)205", "organism": "Fruit fly", "refseq_name": "suppressor of variegation 205, isoform A", "refseq_ac": [ { "id": "NP_476755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476755", "type": "external" } ], "gene_names_uniprotkb": "Su(var)205; CG8409; HP1a; HP1; Su(var)2-5", "gene_names_refseq": "CBX5; CG8409; DmHP-1; DmHP1; Dmel\\CG8409; E(var)29A; E(var)29; FBgn0003607; HP-1; HP1-VS; HP1A; HP1alpha; HP1a; HP1; Hp1a; Hp1; SU(VAR)205; Su(Var)2-5; Su(Var)205; Su(var)2-05; Su(var)2-501; Su(var)2-5; Su(var)205; Su(var)29A; Su(var)[205]; Su(var); Su-var(2)5; Su[Var]205; Su[var]205; Sur(var)205; Suvar(2)5; Suvar2-5; dHP-1a; dHP1a; dHP1; hp1a; hp1; su(var)205", "protein_names_uniprotkb": "Heterochromatin protein 1; HP1; Non-histone chromosomal protein C1A9 antigen", "protein_names_refseq": "C1A9-nuclear-antigen; CG8409-PA; Su(var)2-5; Su(var)205-PA; heterochromatic protein 1a; heterochromatic protein 1; heterochromatic protein; heterochromatin factor 1; heterochromatin protein 1A; heterochromatin protein-1; heterochromatin-binding protein; heterochromatin-protein-1; histone protein 1; suppressor of variegated 205; suppressor of variegation 205, isoform A; suppressor of variegation 205", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283)", "pathway": " (dme:Dmel_CG8409); (R-DME-73772); (R-DME-8953750); (R-DME-983231); (R-DME-9843940)", "pathway_count": 5, "publication_count": 24, "publication_id_list": "10731132;11408576;11566886;11859155;11867540;12510197;12537569;12537572;12808023;12826664;1708124;17372656;17875665;18327897;18984573;19181850;19240120;20057353;20679394;2124708;26110638;26389589;3099166;9378752", "class_list": "", "function": "Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation (PubMed:26389589). Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression (PubMed:11859155, PubMed:26389589). Stabilizes chromatin-associated RNAs probably by binding to them and thereby preventing their degradation (PubMed:26389589). Associates with, and may be a part of, the HipHop-HOAP complex that recruits the MTV complex to form the terminin telomere-capping complex, which binds to chromosome ends in a sequence-independent manner and prevents telomere fusion (PubMed:12510197, PubMed:20057353). Telomere capping is independent of the origin recognition complex (ORC) (PubMed:12510197)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V0F1;B6UVR4;B6UVS1;B6UVS2;B6UVS3;B6UVT2;B6UVT6;B6UVT7;Q9VLR6", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0030674 protein-macromolecule adaptor activity;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000775 chromosome, centromeric region;GO:0000793 condensed chromosome;GO:0005694 chromosome", "go_biological_process": "GO:0031508 pericentric heterochromatin formation;GO:1905634 regulation of protein localization to chromatin;GO:0000278 mitotic cell cycle;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P05205-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P05389-1", "uniprot_id": [ { "id": "RLA2_DROME", "url": "https://www.uniprot.org/uniprot/P05389", "type": "external" } ], "mass": 11757.0, "length": 113, "protein_name": "Large ribosomal subunit protein P2", "gene_name": "RpLP2", "organism": "Fruit fly", "refseq_name": "ribosomal protein LP2", "refseq_ac": [ { "id": "NP_523764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523764", "type": "external" } ], "gene_names_uniprotkb": "RpLP2; CG4918; RpP1; rpA1", "gene_names_refseq": "BcDNA:SD22208; CG4918; Dmel\\CG4918; LP2; P2; RLA2_DROME; RpA1; RpLP2; RpP1; RplP2; Rplp2; T1; Tp1; bs34h02.y1; chr2R:12101099..12101299; rpA1", "protein_names_uniprotkb": "Large ribosomal subunit protein P2; 60S acidic ribosomal protein P2; Acidic ribosomal protein RPA1", "protein_names_refseq": "ACIDIC RIBOSOMAL PROTEIN LP2; CG4918-PA; RpLP2-PA; Temporal-protein-1; ribosomal protein A1; ribosomal protein LP2; ribosomal protein P1; rpA1; temporal protein 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4918); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;18327897;3103101", "class_list": "", "function": "Plays an important role in the elongation step of protein synthesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZK7;Q8MRV1;Q9V7R6", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0002182 cytoplasmic translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P05389-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P05527-1", "uniprot_id": [ { "id": "HMIN_DROME", "url": "https://www.uniprot.org/uniprot/P05527", "type": "external" } ], "mass": 60863.0, "length": 576, "protein_name": "Homeobox protein invected", "gene_name": "inv", "organism": "Fruit fly", "refseq_name": "invected, isoform B", "refseq_ac": [ { "id": "NP_523699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523699", "type": "external" } ], "gene_names_uniprotkb": "inv; CG17835", "gene_names_refseq": "CG17835; Dmel\\CG17835; Engrailed/Invected; INV; IV; Inv; er; inv; in", "protein_names_uniprotkb": "Homeobox protein invected", "protein_names_refseq": "CG17835-PB; engrailed-invected; engrailed-related; inv-PB; invected, isoform B; invected; transcript group IV", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autistic disorder (Disease Ontology:DOID:12849)", "pathway": " (dme:Dmel_CG17835)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;2892756;9165116", "class_list": "", "function": "Engrailed (en) and invected (inv) are functionally redundant transcription factors in neuronal precursor cell NB5-3 specification. Inv is unable to substitute for en in other regulatory processes such as maintaining gsb expression in the neuroectoderm after stage 10 of embryogenesis. Maintenance of gsb expression in row 5 of the neuroectoderm involves an as yet unidentified short range signaling molecule., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZD7;Q0E9C1;Q5U0Z5;Q8T3Z5;Q9V600", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0007400 neuroblast fate determination;GO:0007386 compartment pattern specification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P05527-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P05661-3", "uniprot_id": [ { "id": "MYSA_DROME", "url": "https://www.uniprot.org/uniprot/P05661", "type": "external" } ], "mass": 224609.0, "length": 1962, "protein_name": "Myosin heavy chain, muscle", "gene_name": "Mhc", "organism": "Fruit fly", "refseq_name": "myosin heavy chain, isoform O", "refseq_ac": [ { "id": "NP_001162991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162991", "type": "external" } ], "gene_names_uniprotkb": "Mhc; CG17927", "gene_names_refseq": "Bsh; CG17927; DROMHC; Dm II; DmMHC; Dmel\\CG17927; DroMII; Ifm(2)2; Ifm(2)RU1; MHC; MRP; Mhc36B; Mhc; Mrp; MyHC; Myo6; Myosin; Myo; Nup; Sht; Stp; chr2L:16765388..16765564; chr2L:16781880..16782040; ifm(2)2; ifm(2)RU1; ifm(2)RU2; l(2)36Ae; l(2)M66; l(2)k10423; mMHC; mhc; sMHC", "protein_names_uniprotkb": "Myosin heavy chain, muscle", "protein_names_refseq": "CG17927-PO; Mhc-PO; Not-upheld; Shrunken-thorax; beta-myosin heavy chain; indirect flight muscle (2) RU1; indirect flight muscle (2) RU2; muscle myosin II heavy chain; muscle myosin heavy chain; muscle myosin-II; muscle specific myosin II; myosin HC; myosin heavy Chain-PF; myosin heavy chain, isoform O; myosin heavy chain; myosin heavy-chain protein; myosin rod protein; myosin-heavy chain; samba; sarcomeric myosin heavy-chain; shrunken thorax; stuckup", "tax_id": 7227, "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); cardiomyopathy (Disease Ontology:DOID:0050700); stroke (Disease Ontology:DOID:0051061); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); distal myopathy 1 (Disease Ontology:DOID:0070197); familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326); congenital myopathy 6 (Disease Ontology:DOID:0080719); arthrogryposis multiplex congenita (Disease Ontology:DOID:0080954); contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A (Disease Ontology:DOID:0081321); contractures, pterygia, and spondylocarpotarsal fusion syndrome 1B (Disease Ontology:DOID:0081322); spondylocarpotarsal synostosis syndrome (Disease Ontology:DOID:0090116); atrial heart septal defect 3 (Disease Ontology:DOID:0110108); hypertrophic cardiomyopathy 1 (Disease Ontology:DOID:0110307); hypertrophic cardiomyopathy 14 (Disease Ontology:DOID:0110320); dilated cardiomyopathy 1EE (Disease Ontology:DOID:0110453); dilated cardiomyopathy 1S (Disease Ontology:DOID:0110454); autosomal recessive hyaline body myopathy (Disease Ontology:DOID:0111268); autosomal dominant hyaline body myopathy (Disease Ontology:DOID:0111269); distal arthrogryposis type 1 (Disease Ontology:DOID:0111596); distal arthrogryposis type 2B (Disease Ontology:DOID:0111599); distal arthrogryposis type 2B3 (Disease Ontology:DOID:0111602); distal arthrogryposis type 7 (Disease Ontology:DOID:0111603); distal arthrogryposis type 2A (Disease Ontology:DOID:0111605); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); distal myopathy (Disease Ontology:DOID:11720); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); sick sinus syndrome (Disease Ontology:DOID:13884); disease of cellular proliferation (Disease Ontology:DOID:14566); hypothyroidism (Disease Ontology:DOID:1459); congenital heart disease (Disease Ontology:DOID:1682); atrial heart septal defect (Disease Ontology:DOID:1882); myotonia congenita (Disease Ontology:DOID:2106); inclusion body myositis (Disease Ontology:DOID:3429); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384); restrictive cardiomyopathy (Disease Ontology:DOID:397); myopathy (Disease Ontology:DOID:423); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); muscular dystrophy (Disease Ontology:DOID:9884); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)", "pathway": " (dme:Dmel_CG17927)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;1907912;2116987;2431291;2506434;3038896", "class_list": "", "function": "Muscle contraction., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 43, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18392;O18393;Q24412;Q7JN62;Q7JN63;Q7JQ08;Q7JQ09;Q7M4K4;Q8INZ9;Q8IP00;Q8IP01;Q8IP02;Q8IP03;Q8IP04;Q8IP05;Q8IP06;Q8IP07;Q8IP08;Q8IP09;Q8IP10;Q9TY21;Q9TY22;Q9TYD7;Q9VJI3", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0051015 actin filament binding;GO:0008307 structural constituent of muscle", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030017 sarcomere;GO:0032982 myosin filament;GO:0031672 A band;GO:0016460 myosin II complex", "go_biological_process": "GO:0006936 muscle contraction;GO:0007517 muscle organ development;GO:0050821 protein stabilization;GO:0045214 sarcomere organization;GO:0042692 muscle cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P05661-3", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P06604-1", "uniprot_id": [ { "id": "TBA2_DROME", "url": "https://www.uniprot.org/uniprot/P06604", "type": "external" } ], "mass": 49967.0, "length": 449, "protein_name": "Tubulin alpha-2 chain", "gene_name": "alphaTub85E", "organism": "Fruit fly", "refseq_name": "alpha-Tubulin at 85E", "refseq_ac": [ { "id": "NP_524297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524297", "type": "external" } ], "gene_names_uniprotkb": "alphaTub85E; CG9476; TUBA85E", "gene_names_refseq": "2t; 85E; ALPHA 85E; CG9476; DTA3; Dmel\\CG9476; TUBA85E; Tub1D; Tub; T; a2t; aTub85E; alpha-Tub85E; alpha-Tub; alpha-tubulin; alpha-tub; alpha2t; alpha2; alpha85E-tub; alpha85E; alphaTub2; alphaTub84E; alphaTub85E; alphaTub; alphatub85E", "protein_names_uniprotkb": "Tubulin alpha-2 chain; 3.6.5.-", "protein_names_refseq": "CG9476-PA; alpha tubulin; alpha-Tubulin 85E; alpha-Tubulin at 85E; alpha2-tubulin; alpha2tubulin; alpha85E-tubulin; alphaTub85E-PA; alphatubulin", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); polymicrogyria (Disease Ontology:DOID:0080918); lissencephaly 3 (Disease Ontology:DOID:0112232); microlissencephaly (Disease Ontology:DOID:0112234); keratoconus (Disease Ontology:DOID:10126); congenital nervous system abnormality (Disease Ontology:DOID:2490)", "pathway": " (dme:Dmel_CG9476); (R-DME-3371497); (R-DME-6807878); (R-DME-6811436)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;3095837;8500545", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5RJ60;Q8MYS4;Q9VH86", "ec_number_list": [ { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.4.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.41", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" } ], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005876 spindle microtubule;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0000226 microtubule cytoskeleton organization;GO:0009826 unidimensional cell growth", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P06604-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P06606-1", "uniprot_id": [ { "id": "TBA4_DROME", "url": "https://www.uniprot.org/uniprot/P06606", "type": "external" } ], "mass": 51181.0, "length": 462, "protein_name": "Tubulin alpha-4 chain", "gene_name": "alphaTub67C", "organism": "Fruit fly", "refseq_name": "alpha-Tubulin at 67C", "refseq_ac": [ { "id": "NP_524009", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524009", "type": "external" } ], "gene_names_uniprotkb": "alphaTub67C; CG8308; TubA67C", "gene_names_refseq": "4t; 67C; ALPHA 67C; CG8308; D.m.ALPHA-67C; DTA2; Dmel\\CG8308; Fs(3)Kavar; Fs(3)Kav; Fs(3)Sz14; Fs(3)Sz22; Fs(3)Tomaj; Fs(3)Tom; Kavar; Tom; Tub1E; Tub; T; aTub67C; alpha-Tub67C; alpha-Tubulin67C; alpha-Tub; alpha-tub67C; alpha-tubulin[4]; alpha-tubulin; alpha-tub; alpha4-tubulin; alpha4-t; alpha4Tub67C; alpha4t; alpha4; alpha67C; alphaTUB; alphaTub 67C; alphaTub4; alphaTub67C; alphaTub[67C]; alphaTubulin; alphaTub; alphatub67C; alphatub; gamma-Tub; mum-tub67C; tub67c; tubulin; tub", "protein_names_uniprotkb": "Tubulin alpha-4 chain; 3.6.5.-", "protein_names_refseq": "CG8308-PA; alpha tubulin 67C; alpha tubulin; alpha-Tubulin at 67C; alpha-Tubulin; alpha4-tubulin; alphaTub67C-PA; alphaTubulin 67C; alphaTubulin67C; alphatubulin; female sterile (3) kavar; kavar; tomaj; tubulin at 67C; tubulin67C", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); polymicrogyria (Disease Ontology:DOID:0080918); lissencephaly 3 (Disease Ontology:DOID:0112232); microlissencephaly (Disease Ontology:DOID:0112234)", "pathway": " (dme:Dmel_CG8308); (R-DME-3371497); (R-DME-6807878); (R-DME-6811436)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10731132;12537572;3095837", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VT30", "ec_number_list": [ { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.4.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.41", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" } ], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0055028 cortical microtubule;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005886 plasma membrane", "go_biological_process": "GO:0009792 embryo development ending in birth or egg hatching;GO:0000278 mitotic cell cycle;GO:0007417 central nervous system development;GO:0040016 embryonic cleavage;GO:0007422 peripheral nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P06606-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P07663-1", "uniprot_id": [ { "id": "PER_DROME", "url": "https://www.uniprot.org/uniprot/P07663", "type": "external" } ], "mass": 127364.0, "length": 1218, "protein_name": "Period circadian protein", "gene_name": "per", "organism": "Fruit fly", "refseq_name": "period, isoform B", "refseq_ac": [ { "id": "NP_001259194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259194", "type": "external" } ], "gene_names_uniprotkb": "per; CG2647", "gene_names_refseq": "CG2647; Clk; Dmel\\CG2647; EG:155E2.4; PER; Per-2; Per; clk-6; dPER; dPer; dmper; dper; mel_per; per", "protein_names_uniprotkb": "Period circadian protein; CLK-6; Protein clock-6", "protein_names_refseq": "CG2647-PB; PERIOD; clock-6; dperiod; per-PB; period clock protein; period, isoform B", "tax_id": 7227, "disease": "advanced sleep phase syndrome (Disease Ontology:DOID:0050628); fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); alcohol dependence (Disease Ontology:DOID:0050741); advanced sleep phase syndrome 1 (Disease Ontology:DOID:0110011); advanced sleep phase syndrome 3 (Disease Ontology:DOID:0110013); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); alcohol use disorder (Disease Ontology:DOID:1574); bipolar disorder (Disease Ontology:DOID:3312); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG2647); (R-DME-432395); (R-DME-432490); (R-DME-432501); (R-DME-432524); (R-DME-432553); (R-DME-432620); (R-DME-538898); (R-DME-9932298)", "pathway_count": 9, "publication_count": 60, "publication_id_list": "10409723;10417378;10481010;10684876;10731132;10731137;11007323;11430804;11440719;11585911;12122057;12351680;12432393;12442174;12447397;12537572;12546820;12563262;12581523;12944510;14759367;14980226;15178801;15258584;15288072;15629718;15930393;16319317;16410523;16543224;16603629;16794082;17418796;17452449;17575052;18474612;18593878;18815259;19139270;19185492;19726650;20159956;20861372;24086144;24210908;27814361;30246807;30703153;3081818;3087625;3102970;36994075;7481773;8134384;8436278;8596938;8600384;8938123;9674431;9808471", "class_list": "", "function": "Essential for biological clock functions. Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms. Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition. Required for binding of cwo to the E box regions in the promoters of target genes of the transcriptional activator Clock, probably by binding to Clock-cycle heterodimers, reducing their affinity for E box binding and allowing cwo to bind instead (PubMed:27814361)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 12, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 12, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 12, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 28, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 9, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "M9PGJ3;O17483;O76882;O76883;O76884;O76885;Q24446;Q24447;Q24448;Q24449;Q6PVA3;Q8MLY0;Q9GN20;Q9GN51;Q9GQH9;Q9GV48;Q9GV53;Q9GV54;Q9GV55;Q9W4X0", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0003714 transcription corepressor activity;GO:0000976 transcription cis-regulatory region binding;GO:0003712 transcription coregulator activity;GO:0001222 transcription corepressor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:1904059 regulation of locomotor rhythm;GO:0060086 circadian temperature homeostasis;GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006979 response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 7.4, "record_id": "P07663-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P07701-1", "uniprot_id": [ { "id": "SGS5_DROME", "url": "https://www.uniprot.org/uniprot/P07701", "type": "external" } ], "mass": 18821.0, "length": 163, "protein_name": "Salivary glue protein Sgs-5", "gene_name": "Sgs5", "organism": "Fruit fly", "refseq_name": "salivary gland secretion 5", "refseq_ac": [ { "id": "NP_524388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524388", "type": "external" } ], "gene_names_uniprotkb": "Sgs5; CG7596", "gene_names_refseq": "BcDNA:LP02306; CG7596; Dmel\\CG7596; LP02306; SGS-5; Sgs-5; Sgs5; Sgs; sgs5", "protein_names_uniprotkb": "Salivary glue protein Sgs-5", "protein_names_refseq": "CG7596-PA; Sgs5-PA; salivary gland secretion 5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7596)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;3098981", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VEI5", "ec_number_list": [], "go_molecular_function": "GO:0140073 bioadhesive activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007594 puparial adhesion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P07701-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08044-1", "uniprot_id": [ { "id": "SNAI_DROME", "url": "https://www.uniprot.org/uniprot/P08044", "type": "external" } ], "mass": 42955.0, "length": 390, "protein_name": "Protein snail", "gene_name": "sna", "organism": "Fruit fly", "refseq_name": "snail", "refseq_ac": [ { "id": "NP_476732", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476732", "type": "external" } ], "gene_names_uniprotkb": "sna; CG3956", "gene_names_refseq": "BG:DS01845.1; CG3956; Dmel\\CG3956; SNAIL; SNA; Sco; Snail; Sna; br28; br29; l(2)35Db; l(2)br28; l(2)br29; l(3)br28; l35Db; sna; sn", "protein_names_uniprotkb": "Protein snail", "protein_names_refseq": "CG3956-PA; SNa; scutoid; sna-PA; snail", "tax_id": 7227, "disease": "carcinoma (Disease Ontology:DOID:305); piebaldism (Disease Ontology:DOID:3263); Waardenburg syndrome (Disease Ontology:DOID:9258)", "pathway": " (dme:Dmel_CG3956)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10471707;10731132;11290303;12537572;1438276;3683556", "class_list": "", "function": "Essential for the correct specification of ventral-dorsal patterns., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V3D3", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048749 compound eye development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P08044-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08646-1", "uniprot_id": [ { "id": "RAS1_DROME", "url": "https://www.uniprot.org/uniprot/P08646", "type": "external" } ], "mass": 21594.0, "length": 189, "protein_name": "Ras-like protein 1", "gene_name": "Ras85D", "organism": "Fruit fly", "refseq_name": "Ras oncogene at 85D", "refseq_ac": [ { "id": "NP_476699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476699", "type": "external" } ], "gene_names_uniprotkb": "Ras85D; CG9375; Ras1", "gene_names_refseq": "C-ras1; CG9375; D-Ras1; D-Ras; D-ras-1; D-ras1; DRAS1; DRas85D/Ras; DRas; Dm Ras1; Dmel\\CG9375; Dmras85D; Dras1; Dras85D; Dras; E(faf); E(sev)3C; EC3-3; EK3-4; P08646; RAS1; RAS85D; RAS; RTK; Ras 85D; Ras-1; Ras.85D; Ras1/RAs85D; Ras185D; Ras1; Ras85DNt; Ras85D; Ras85d; Ras85; RasI; RasV12; Ras[V12]; Rasv12; Ras; S35097; Su(tor)3-2; dRAS1; dRas1; dRas85D; dRas; dras1; fs(3)05703; l(3)06677; l(3)s1747; p21[Ras1]; ras 1; ras1; ras85B; ras85D; ras[V12]; ras", "protein_names_uniprotkb": "Ras-like protein 1; 3.6.5.2; Dmras85D; Dras1", "protein_names_refseq": "CG9375-PA; Ras GTPase; Ras oncogene at 85B; Ras oncogene at 85D; Ras1; Ras85D-PA; enhancer of faf", "tax_id": 7227, "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); Costello syndrome (Disease Ontology:DOID:0050469); cardiomyopathy (Disease Ontology:DOID:0050700); renal fibrosis (Disease Ontology:DOID:0050855); hepatocellular adenoma (Disease Ontology:DOID:0050868); myelodysplastic syndrome (Disease Ontology:DOID:0050908); cardiofaciocutaneous syndrome (Disease Ontology:DOID:0060233); Noonan syndrome 3 (Disease Ontology:DOID:0060581); Noonan syndrome 6 (Disease Ontology:DOID:0060584); arteriovenous malformations of the brain (Disease Ontology:DOID:0060688); endometrial hyperplasia (Disease Ontology:DOID:0080365); RASopathy (Disease Ontology:DOID:0080690); autoimmune lymphoproliferative syndrome type 4 (Disease Ontology:DOID:0110117); epidermal nevus (Disease Ontology:DOID:0111162); large congenital melanocytic nevus (Disease Ontology:DOID:0111359); cardiofaciocutaneous syndrome 2 (Disease Ontology:DOID:0111461); linear nevus sebaceous syndrome (Disease Ontology:DOID:0111530); oculoectodermal syndrome (Disease Ontology:DOID:0111705); intestinal cancer (Disease Ontology:DOID:10155); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); intellectual disability (Disease Ontology:DOID:1059); Alzheimer's disease (Disease Ontology:DOID:10652); obsessive-compulsive disorder (Disease Ontology:DOID:10933); urinary bladder cancer (Disease Ontology:DOID:11054); heart disease (Disease Ontology:DOID:114); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); leukemia (Disease Ontology:DOID:1240); autistic disorder (Disease Ontology:DOID:12849); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); squamous cell carcinoma (Disease Ontology:DOID:1749); pancreatic cancer (Disease Ontology:DOID:1793); melanoma (Disease Ontology:DOID:1909); autoimmune hepatitis (Disease Ontology:DOID:2048); kidney cancer (Disease Ontology:DOID:263); transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial adenocarcinoma (Disease Ontology:DOID:2870); endometrial carcinoma (Disease Ontology:DOID:2871); endometriosis (Disease Ontology:DOID:289); carcinoma (Disease Ontology:DOID:305); glioblastoma (Disease Ontology:DOID:3068); malignant astrocytoma (Disease Ontology:DOID:3069); high grade glioma (Disease Ontology:DOID:3070); anaplastic astrocytoma (Disease Ontology:DOID:3078); skin benign neoplasm (Disease Ontology:DOID:3165); Noonan syndrome (Disease Ontology:DOID:3490); Lynch syndrome (Disease Ontology:DOID:3883); lung adenocarcinoma (Disease Ontology:DOID:3910); papillary thyroid carcinoma (Disease Ontology:DOID:3969); cervical cancer (Disease Ontology:DOID:4362); seminoma (Disease Ontology:DOID:4440); renal cell carcinoma (Disease Ontology:DOID:4450); pancreatic carcinoma (Disease Ontology:DOID:4905); bronchiolo-alveolar adenocarcinoma (Disease Ontology:DOID:4926); Klatskin's tumor (Disease Ontology:DOID:4927); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); liver cirrhosis (Disease Ontology:DOID:5082); stomach carcinoma (Disease Ontology:DOID:5517); phobic disorder (Disease Ontology:DOID:591); fibrillary astrocytoma (Disease Ontology:DOID:6726); hepatocellular carcinoma (Disease Ontology:DOID:684); liver carcinoma (Disease Ontology:DOID:686); pancreatic mucinous cystadenoma (Disease Ontology:DOID:7235); muscular atrophy (Disease Ontology:DOID:767); myeloid sarcoma (Disease Ontology:DOID:8683); diabetic retinopathy (Disease Ontology:DOID:8947); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); cholangitis (Disease Ontology:DOID:9446); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG9375); (R-DME-1250347); (R-DME-1433557); (R-DME-171007); (R-DME-179812); (R-DME-180336); (R-DME-186763); (R-DME-1963640); (R-DME-210993); (R-DME-2179392); (R-DME-2424491); (R-DME-2871796); (R-DME-375165); (R-DME-3928662); (R-DME-4086398); (R-DME-432553); (R-DME-5218921); (R-DME-5621575); (R-DME-5654688); (R-DME-5654693); (R-DME-5654699); (R-DME-5654700); (R-DME-5654704); (R-DME-5654706); (R-DME-5654712); (R-DME-5654719); (R-DME-5658442); (R-DME-5673000); (R-DME-5673001); (R-DME-5674135); (R-DME-5675221); (R-DME-6798695); (R-DME-8849471); (R-DME-8951936); (R-DME-9607240); (R-DME-9634635); (R-DME-9648002)", "pathway_count": 37, "publication_count": 29, "publication_id_list": "10552039;10731132;11290305;11430804;11440719;12122057;12432393;12442174;12447397;12537569;12537572;12563262;12944510;14759367;16319317;16410523;17418796;18503409;18593878;18815259;19965758;3110012;6430564;7481773;7873789;8596938;8600384;8938123;9674431", "class_list": "", "function": "Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells (PubMed:11290305). During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis (PubMed:19965758)., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 73, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V448", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.4.26.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.26.1", "type": "external" }, { "id": "2.5.1.58", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.58", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "2.5.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.59", "type": "external" }, { "id": "2.1.1.100", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.100", "type": "external" }, { "id": "3.2.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.21", "type": "external" }, { "id": "3.2.1.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.46", "type": "external" }, { "id": "2.7.1.91", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.91", "type": "external" }, { "id": "2.3.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.78", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0001710 mesodermal cell fate commitment;GO:0046534 positive regulation of photoreceptor cell differentiation;GO:0048749 compound eye development;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P08646-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09081-1", "uniprot_id": [ { "id": "BCD_DROME", "url": "https://www.uniprot.org/uniprot/P09081", "type": "external" } ], "mass": 54511.0, "length": 494, "protein_name": "Homeotic protein bicoid", "gene_name": "bcd", "organism": "Fruit fly", "refseq_name": "bicoid, isoform A", "refseq_ac": [ { "id": "NP_476825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476825", "type": "external" } ], "gene_names_uniprotkb": "bcd; CG1034", "gene_names_refseq": "BCD; BG:DS00276.7; Bcd; Bicoid; CG1034; Dm-Bcd; Dmel\\CG1034; bcd; bic; mum; prd4", "protein_names_uniprotkb": "Homeotic protein bicoid; PRD-4", "protein_names_refseq": "CG1034-PA; PRD gene 4; bcd-PA; bicoid, isoform A; bicoid; multimorph", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1034)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10717484;10731132;11455422;12082119;12537569;12537572;16406070;24637116;2752425;2877746;2901954;35363606", "class_list": "", "function": "Segment polarity transcription factor that provides positional cues for the development of head and thoracic segments (PubMed:24637116, PubMed:2901954, PubMed:35363606). Forms a protein concentration gradient that patterns the anterior-posterior axis during embryogenesis and promotes the expression of anterior gap genes, such as hunchback (hb), ocelliless (oc), and buttonhead (btd) (PubMed:24637116, PubMed:2901954, PubMed:35363606). Binds to regulatory DNA sequences containing a 5'-TAATCC-3' sequence motif (PubMed:16406070, PubMed:35363606). Also binds RNA (PubMed:2752425). Interacts with Bin1 to repress transcription of bicoid target genes in the anterior tip of the embryo; a process known as retraction (PubMed:11455422)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5BI92;Q86BA9;Q86BP2;Q8INR7;Q8ST46;Q8STB1;Q8T9S9;Q8T9T0;Q8T9T1;Q95TN3;Q9UAM0;Q9VI47", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0030371 translation repressor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P09081-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09180-1", "uniprot_id": [ { "id": "RL4_DROME", "url": "https://www.uniprot.org/uniprot/P09180", "type": "external" } ], "mass": 45026.0, "length": 401, "protein_name": "Large ribosomal subunit protein uL4", "gene_name": "RpL4", "organism": "Fruit fly", "refseq_name": "ribosomal protein L4", "refseq_ac": [ { "id": "NP_524538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524538", "type": "external" } ], "gene_names_uniprotkb": "RpL4; CG5502; RpL1", "gene_names_refseq": "CG5502; Dmel\\CG5502; L4; Rp L4; RpL1; RpL4; anon-WO0172774.76; chr3R:23749174..23749334; rpL1", "protein_names_uniprotkb": "Large ribosomal subunit protein uL4; 60S ribosomal protein L4; L1", "protein_names_refseq": "60S RIBOSOMAL PROTEIN L4; CG5502-PA; RpL4-PA; ribosomal protein L1; ribosomal protein L4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5502); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;23636399;2492096;3133637;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9I7H6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P09180-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P10035-1", "uniprot_id": [ { "id": "HMH2_DROME", "url": "https://www.uniprot.org/uniprot/P10035", "type": "external" } ], "mass": 45835.0, "length": 418, "protein_name": "Homeobox protein H2.0", "gene_name": "H2.0", "organism": "Fruit fly", "refseq_name": "homeodomain protein 2.0", "refseq_ac": [ { "id": "NP_523488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523488", "type": "external" } ], "gene_names_uniprotkb": "H2.0; CG11607", "gene_names_refseq": "CG11607; Dmel\\CG11607; H2.0", "protein_names_uniprotkb": "Homeobox protein H2.0", "protein_names_refseq": "CG11607-PA; H2.0-PA; homeodomain protein 2.0", "tax_id": 7227, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815)", "pathway": " (dme:Dmel_CG11607)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;1678322;2901348", "class_list": "", "function": "May play a role in pattern formation during embryonic and imaginal development. Is not essential for visceral muscle morphogenesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q1LYZ9;Q8MS25;Q9VMJ3", "ec_number_list": [], "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P10035-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P10181-1", "uniprot_id": [ { "id": "ROUGH_DROME", "url": "https://www.uniprot.org/uniprot/P10181", "type": "external" } ], "mass": 39430.0, "length": 350, "protein_name": "Homeobox protein rough", "gene_name": "ro", "organism": "Fruit fly", "refseq_name": "rough, isoform A", "refseq_ac": [ { "id": "NP_524521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524521", "type": "external" } ], "gene_names_uniprotkb": "ro; CG6348", "gene_names_refseq": "CG6348; DROROUGH; Dmel\\CG6348; Ro; ro", "protein_names_uniprotkb": "Homeobox protein rough", "protein_names_refseq": "CG6348-PA; ro-PA; rough, isoform A; rough", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6348)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;11709152;12537572;1974228;2898735;2903798;40245499", "class_list": "", "function": "Required to establish the unique cell identity of photoreceptors R2 and R5 and consequently for ommatidial assembly in the developing eye imaginal disk. Repression of expression in R8 photoreceptor by senseless (sens) is an essential mechanism of R8 cell fate determination., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q24487;Q4V714;Q9VBA7", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007601 visual perception;GO:0042067 establishment of ommatidial planar polarity", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P10181-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P10351-1", "uniprot_id": [ { "id": "XDH_DROME", "url": "https://www.uniprot.org/uniprot/P10351", "type": "external" } ], "mass": 146927.0, "length": 1335, "protein_name": "Xanthine dehydrogenase", "gene_name": "ry", "organism": "Fruit fly", "refseq_name": "rosy", "refseq_ac": [ { "id": "NP_524337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524337", "type": "external" } ], "gene_names_uniprotkb": "ry; CG7642; XDH", "gene_names_refseq": "CG7642; Dmel\\CG7642; Ry; XDH; XOR; Xdh/ry; Xdh; ry; xdh", "protein_names_uniprotkb": "Xanthine dehydrogenase; 1.17.1.4; Protein rosy locus; XD", "protein_names_refseq": "CG7642-PA; rosy; ry-PA; xanthine DH; xanthine dehydrogenase", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); renal fibrosis (Disease Ontology:DOID:0050855); xanthinuria (Disease Ontology:DOID:0060236); xanthinuria type I (Disease Ontology:DOID:0070452); muscular disease (Disease Ontology:DOID:0080000); interstitial nephritis (Disease Ontology:DOID:1063); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); cardiovascular system disease (Disease Ontology:DOID:1287); cholestasis (Disease Ontology:DOID:13580); Lesch-Nyhan syndrome (Disease Ontology:DOID:1919); hyperuricemia (Disease Ontology:DOID:1920); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); acute kidney failure (Disease Ontology:DOID:3021); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); carotid artery disease (Disease Ontology:DOID:3407); pancreatitis (Disease Ontology:DOID:4989); hepatocellular carcinoma (Disease Ontology:DOID:684); chronic kidney disease (Disease Ontology:DOID:784); peritonitis (Disease Ontology:DOID:8283); cataract (Disease Ontology:DOID:83); multiple myeloma (Disease Ontology:DOID:9538); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG7642); (R-DME-74259); (R-DME-964975); (R-DME-9748787)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;3036645;3036646", "class_list": "", "function": "Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWF5;Q8SXC4;Q9VFZ9", "ec_number_list": [ { "id": "1.17.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.1.4", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0043546 molybdopterin cofactor binding", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0009115 xanthine catabolic process;GO:0006568 L-tryptophan metabolic process;GO:0006525 arginine metabolic process;GO:0006144 purine nucleobase metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P10351-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P12297-2", "uniprot_id": [ { "id": "SUWA_DROME", "url": "https://www.uniprot.org/uniprot/P12297", "type": "external" } ], "mass": 106141.0, "length": 963, "protein_name": "Protein suppressor of white apricot", "gene_name": "su(w[a])", "organism": "Fruit fly", "refseq_name": "suppressor of white-apricot, isoform A", "refseq_ac": [ { "id": "NP_476756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476756", "type": "external" } ], "gene_names_uniprotkb": "su(w[a]); CG3019; su(wa)", "gene_names_refseq": "CG3019; DmSWAP; Dmel\\CG3019; EG:BACR7A4.10; SWAP; Su(w[a]); su(w); su(w[a])-1; su(w[a])-2; su(w[a]); su(wa); su-w; su[wa]", "protein_names_uniprotkb": "Protein suppressor of white apricot", "protein_names_refseq": "CG3019-PA; su(w[a])-PA; suppressor of apricot; suppressor of white-apricot, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3019)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;10731137;12537569;12537572;1655279;18327897;2832151;3443103", "class_list": "", "function": "Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulates its own expression at the level of RNA processing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24543;Q7KW21;Q8MSS2;Q9I7D2;Q9TVZ2", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P12297-2", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P12370-1", "uniprot_id": [ { "id": "KAPC1_DROME", "url": "https://www.uniprot.org/uniprot/P12370", "type": "external" } ], "mass": 40839.0, "length": 353, "protein_name": "cAMP-dependent protein kinase catalytic subunit 1", "gene_name": "Pka-C1", "organism": "Fruit fly", "refseq_name": "protein kinase, cAMP-dependent, catalytic subunit 1, isoform D", "refseq_ac": [ { "id": "NP_476977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476977", "type": "external" } ], "gene_names_uniprotkb": "Pka-C1; CG4379; CdkA; DC0", "gene_names_refseq": "6353; CG4379; CdkA; Cos-1; Cos1; Cos; C; DC0; DCO; Dc0; Dco; Dcpk; Dmel\\CG4379; PKA CI; PKA Cl; PKA-C1; PKA-C; PKAC1; PKAcA; PKAc; PKA; Pka-C1; Pka-C; PkaC1; Pka; cos1; dPKA; dc0; dcO; dco; l(2)01272; l(2)cos[[1]]; l(2)s4402; pKA; pkA; pka C1; pka-C1; pka-c1; pka", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit 1; 2.7.11.11; PKA C; Protein kinase DC0", "protein_names_refseq": "CG4379-PD; Costal-1; PKA catalytic subunit; Pka-C1-PD; cAMP-dependent protein kinase 1; cAMP-dependent protein kinase; catalytic subunit of PKA; catalytic subunit of cAMP-dependent protein kinase; costal; protein kinase A; protein kinase, cAMP-dependent, catalytic subunit 1, isoform D", "tax_id": 7227, "disease": "adrenal cortical adenoma (Disease Ontology:DOID:0050891); primary pigmented nodular adrenocortical disease 4 (Disease Ontology:DOID:0070549); platelet-type bleeding disorder 19 (Disease Ontology:DOID:0111048); alcohol use disorder (Disease Ontology:DOID:1574); brain ischemia (Disease Ontology:DOID:2316); fibrolamellar carcinoma (Disease Ontology:DOID:5015); congestive heart failure (Disease Ontology:DOID:6000); amphetamine abuse (Disease Ontology:DOID:670)", "pathway": " (dme:Dmel_CG4379); (R-DME-163615); (R-DME-164378); (R-DME-180024); (R-DME-209159); (R-DME-209190); (R-DME-209360); (R-DME-381676); (R-DME-392517); (R-DME-422356); (R-DME-432040); (R-DME-442720); (R-DME-5578775); (R-DME-5610785); (R-DME-5610787); (R-DME-5621575); (R-DME-9634597); (R-DME-983231); (R-DME-9837999); (R-DME-9856530)", "pathway_count": 20, "publication_count": 28, "publication_id_list": "10102270;10409506;10458606;10477300;10557210;10731132;10825151;11090136;11912487;11914126;11955435;12231619;12537569;12537572;14636583;15063184;15691767;16299518;16326393;16386907;17925225;2828348;29444420;29473541;3215511;9215627;9482888;9601642", "class_list": "", "function": "Serine/threonine-protein kinase involved in memory formation (PubMed:29473541). Promotes long-term memory by phosphorylating meng and by regulating CrebB protein stability and activity (PubMed:29473541). As part of ethanol response in the glia, mediates ethanol-induced structural remodeling of actin cytoskeleton and perineurial membrane topology when anchored to the membrane (PubMed:29444420)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0I0;Q9VL99", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" }, { "id": "7.2.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.10", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.5", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0042048 olfactory behavior;GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P12370-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P12881-1", "uniprot_id": [ { "id": "PSA1_DROME", "url": "https://www.uniprot.org/uniprot/P12881", "type": "external" } ], "mass": 31059.0, "length": 279, "protein_name": "Proteasome subunit alpha type-1", "gene_name": "Prosalpha6", "organism": "Fruit fly", "refseq_name": "proteasome alpha6 subunit, isoform B", "refseq_ac": [ { "id": "NP_001285798", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285798", "type": "external" } ], "gene_names_uniprotkb": "Prosalpha6; CG4904; PROS-35; Pros35", "gene_names_refseq": "143314_at; Alpha-6; CG4904; Dmel\\CG4904; PROS-35; PROS-Dm35; PSMA1; Pros alpha6; Pros-35; Pros-Dm35; Pros35; Prosalpha6; alpha-6; alpha6; alpha_dm; anon-SAGE:Wang-116; pros 35; pros35", "protein_names_uniprotkb": "Proteasome subunit alpha type-1; PROS-Dm35; Proteasome 35 kDa subunit", "protein_names_refseq": "20S alpha6 subunit; 20s proteasome; CG4904-PB; Prosalpha6-PB; alpha-subunit of 20S proteasome; alpha6; anon-SAGE:Wang-116; proteasome 35 kD subunit; proteasome 35-kDa subunit; proteasome 35kD subunit; proteasome 35kDa subunit; proteasome alpha6 subunit, isoform B", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG4904); (R-DME-1169091); (R-DME-1234176); (R-DME-1236974); (R-DME-1236978); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209406); (R-DME-209461); (R-DME-216167); (R-DME-2467813); (R-DME-2871837); (R-DME-350562); (R-DME-382556); (R-DME-432395); (R-DME-432524); (R-DME-432626); (R-DME-450408); (R-DME-4608870); (R-DME-4641257); (R-DME-4641258); (R-DME-5358346); (R-DME-538864); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5632684); (R-DME-5658442); (R-DME-5676590); (R-DME-5689603); (R-DME-5689880); (R-DME-68867); (R-DME-68949); (R-DME-69017); (R-DME-69601); (R-DME-75815); (R-DME-8854050); (R-DME-8939236); (R-DME-8939902); (R-DME-8941858); (R-DME-8948751); (R-DME-8951664); (R-DME-9020702); (R-DME-9755511); (R-DME-9762114); (R-DME-983168); (R-DME-9907900); (R-DME-9912633); (R-DME-9929491); (R-DME-9932298); (R-DME-9954709)", "pathway_count": 58, "publication_count": 38, "publication_id_list": "10102270;10417378;10458606;10481010;10731132;11585911;12231619;12432393;12442174;12537569;12537572;12973300;1374331;15178801;15258584;15331761;16139204;16299518;16326393;16386907;16543224;16603629;16651542;16740475;16794082;17102630;17925225;18519643;18593878;19185492;23622245;2477245;7705656;8948598;9025065;9215627;9553105;9990853", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZ22;Q9VL23", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008340 determination of adult lifespan;GO:0007370 ventral furrow formation", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "P12881-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P12982-1", "uniprot_id": [ { "id": "PP12_DROME", "url": "https://www.uniprot.org/uniprot/P12982", "type": "external" } ], "mass": 34542.0, "length": 302, "protein_name": "Serine/threonine-protein phosphatase alpha-2 isoform", "gene_name": "Pp1-87B", "organism": "Fruit fly", "refseq_name": "protein phosphatase 1 at 87B", "refseq_ac": [ { "id": "NP_524937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524937", "type": "external" } ], "gene_names_uniprotkb": "Pp1-87B; CG5650", "gene_names_refseq": "87B; CG5650; DmPp1-87B; Dmel\\CG5650; PP-1alpha; PP1 87B; PP1 beta87b; PP1-87B; PP187B; PP1A87B; PP1B; PP1alpha-87B; PP1alpha87B; PP1alpha[[2]]; PP1a; PP1c 87B; PP1c; PP1; PPI 87B; Pp-1alpha; Pp1-87Bb; Pp1-87B; Pp1.87B; Pp1alpha-87B; Pp1; Ppl-87B; Su(Var)3-6; Su(var)(3)6; Su(var)3-6; Su-var(3)6; Suvar(3)6; ck19; dPP1beta; l(3)87Bg; l(3)ck19; l(3)j6E7; pp1-87B; pp1-87; pp187B; su-var(3)6", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase alpha-2 isoform; 3.1.3.16", "protein_names_refseq": "CG5650-PA; Pp1-87B-PA; protein phosphatase 1 at 87B; protein phosphatase 1; suppressor of variegation", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG5650); (R-DME-350416); (R-DME-350480); (R-DME-538898); (R-DME-9770562)", "pathway_count": 5, "publication_count": 15, "publication_id_list": "10570971;10731132;11301004;11874917;12537569;12537572;1330679;15269282;17007873;17575052;18412953;2175717;2550221;26022086;29746464", "class_list": "", "function": "Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4PIY5;Q9VG75", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0017018 myosin phosphatase activity", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005700 polytene chromosome", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0005981 regulation of glycogen catabolic process;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P12982-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P15619-1", "uniprot_id": [ { "id": "SRYC_DROME", "url": "https://www.uniprot.org/uniprot/P15619", "type": "external" } ], "mass": 95314.0, "length": 869, "protein_name": "Serendipity locus protein H-1", "gene_name": "wdn", "organism": "Fruit fly", "refseq_name": "wings down", "refseq_ac": [ { "id": "NP_476900", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476900", "type": "external" } ], "gene_names_uniprotkb": "wdn; CG1454; Sry-c; pqp; sry h-1", "gene_names_refseq": "CG1454; Dmel\\CG1454; Sryc; pqp; sry h-l; sry-c; sry-h1; wdn", "protein_names_uniprotkb": "Serendipity locus protein H-1; Protein pourquoi-pas; Protein wings-down", "protein_names_refseq": "CG1454-PA; pourquoi-pas; serendipity cognate; serendipity-cognate; wdn-PA; wings down", "tax_id": 7227, "disease": "Birt-Hogg-Dube syndrome (Disease Ontology:DOID:0050676)", "pathway": " (dme:Dmel_CG1454)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;1592256;3141791", "class_list": "", "function": "May belong to a complex set of multifingered proteins which play an important role in gene activation or regulation at early embryonic stages through a maximal accumulation of their transcripts (or protein product) in the mature oocyte., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VAT4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P15619-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17207-1", "uniprot_id": [ { "id": "SER3_DROME", "url": "https://www.uniprot.org/uniprot/P17207", "type": "external" } ], "mass": 29620.0, "length": 272, "protein_name": "Serine protease 3", "gene_name": "Jon99Ci", "organism": "Fruit fly", "refseq_name": "jonah 99Ci", "refseq_ac": [ { "id": "NP_524555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524555", "type": "external" } ], "gene_names_uniprotkb": "Jon99Ci; CG17951; SER3; Ser99Dc", "gene_names_refseq": "143341_at; 99Calpha; CG17951; CG31039; Dmel\\CG31039; JON99CI; Jon99B; Jon99C1; Jon99C2; Jon99Calphai; Jon99Calpha; Jon99Cbetai; Jon99Cbeta; Jon99Ci; Jon99C; JonC; SER3; SP150; Ser3; Ser99Dc; ser99Dc", "protein_names_uniprotkb": "Serine protease 3; 3.4.21.-; Protein Jonah 99Ci", "protein_names_refseq": "CG31039-PA; Jon99Ci-PA; jonah 99 Ci; jonah 99C alpha; jonah 99C beta; jonah 99Ci; serine protease 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31039)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;2469005", "class_list": "", "function": "Its major function may be to aid in digestion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VAD8", "ec_number_list": [], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0017171 serine hydrolase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P17207-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17704-1", "uniprot_id": [ { "id": "RS17_DROME", "url": "https://www.uniprot.org/uniprot/P17704", "type": "external" } ], "mass": 15285.0, "length": 131, "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RpS17", "organism": "Fruit fly", "refseq_name": "ribosomal protein S17", "refseq_ac": [ { "id": "NP_524002", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524002", "type": "external" } ], "gene_names_uniprotkb": "RpS17; CG3922; M(3)67C", "gene_names_refseq": "BcDNA:RE44119; CG3922; D9; Dmel\\CG3922; M(3)67C; M(3)67; M(3)RpS17; M(3)S33; M(3)i(55); M(3)i[55]; M(3)i; M(3)q; M(3L)i[55]; M(3L)i; Minute; M; RPS17; RS17_DROME; Rp S17; RpS17; Rps17; S17e; anon-EST:Posey48; l(3)67BDo; l(3)dtOA4; minute; rpS17", "protein_names_uniprotkb": "Small ribosomal subunit protein eS17; 40S ribosomal protein S17", "protein_names_refseq": "CG3922-PB; Minute(3)67C; RpS17-PB; minute; ribosomal protein S17", "tax_id": 7227, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); Diamond-Blackfan anemia 4 (Disease Ontology:DOID:0111890); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (dme:Dmel_CG3922); (R-DME-156827); (R-DME-1799339); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 12, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23636399;2507396", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V3P5", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P17704-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17917-1", "uniprot_id": [ { "id": "PCNA_DROME", "url": "https://www.uniprot.org/uniprot/P17917", "type": "external" } ], "mass": 28830.0, "length": 260, "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "organism": "Fruit fly", "refseq_name": "proliferating cell nuclear antigen, isoform A", "refseq_ac": [ { "id": "NP_476905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476905", "type": "external" } ], "gene_names_uniprotkb": "PCNA; CG9193; PCNA1; mus209", "gene_names_refseq": "53/13; CG9193; DmPCNA1; DmPCNA; Dmel\\CG9193; MUS209; Mus209; PCNA/mus209; PCNA1; PCNA; Pcna; dPCNA; l(2)02448; l(2)56Fa; l(2)56F; l(2)s1534; mus 209; mus209; pcna", "protein_names_uniprotkb": "DNA sliding clamp PCNA; Cyclin; Mutagen-sensitive 209 protein; PCNA; Proliferating cell nuclear antigen", "protein_names_refseq": "CG9193-PA; PCNA-PA; Proliferating-cell-nuclear-antigen; mutagen-sensitive 209; proliferating cell nuclear antigen, isoform A; proliferating cell nuclear antigen; proliferating-cell nuclear antigen", "tax_id": 7227, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); mucositis (Disease Ontology:DOID:0080178); ataxia-telangiectasia-like disorder 2 (Disease Ontology:DOID:0081385); stomach cancer (Disease Ontology:DOID:10534); sciatic neuropathy (Disease Ontology:DOID:11446); osteoporosis (Disease Ontology:DOID:11476); Lewy body dementia (Disease Ontology:DOID:12217); leiomyoma (Disease Ontology:DOID:127); obstructive jaundice (Disease Ontology:DOID:13603); hypothyroidism (Disease Ontology:DOID:1459); nephroblastoma (Disease Ontology:DOID:2154); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); invasive ductal carcinoma (Disease Ontology:DOID:3008); liver cancer (Disease Ontology:DOID:3571); seminoma (Disease Ontology:DOID:4440); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG9193); (R-DME-110312); (R-DME-110314); (R-DME-110320); (R-DME-5358565); (R-DME-5651801); (R-DME-5655862); (R-DME-5656121); (R-DME-5656169); (R-DME-5696400); (R-DME-6782135); (R-DME-6804114); (R-DME-69091); (R-DME-69166); (R-DME-69183)", "pathway_count": 15, "publication_count": 11, "publication_id_list": "10731132;12537569;12537572;1360647;17087725;19081076;1968224;1973166;40245499;7907981;9310333", "class_list": "", "function": "Confers DNA tethering and processivity to DNA polymerases and other proteins. Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of DNA replication by increasing the polymerases' processivity during elongation of the leading strand., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 18, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q540V1;Q9V909", "ec_number_list": [], "go_molecular_function": "GO:0030337 DNA polymerase processivity factor activity;GO:0003677 DNA binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0043626 PCNA complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006272 leading strand elongation;GO:0042542 response to hydrogen peroxide;GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0006298 mismatch repair", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P17917-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17971-2", "uniprot_id": [ { "id": "KCNAL_DROME", "url": "https://www.uniprot.org/uniprot/P17971", "type": "external" } ], "mass": 64570.0, "length": 571, "protein_name": "Potassium voltage-gated channel protein Shal", "gene_name": "Shal", "organism": "Fruit fly", "refseq_name": "shaker cognate l, isoform B", "refseq_ac": [ { "id": "NP_001097646", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097646", "type": "external" } ], "gene_names_uniprotkb": "Shal; CG9262; SHAL2", "gene_names_refseq": "CG9262; DNK[[v]]4; Dmel\\CG9262; K[[v]]4; Kv4/Shal; Kv4; Sh-l; ShaI; Shal; Shl; dShal; shaI; shal", "protein_names_uniprotkb": "Potassium voltage-gated channel protein Shal; Shaker cognate l; Shal2", "protein_names_refseq": "CG9262-PB; Shaker-like; Shal-PB; shaker cognate 1; shaker cognate L; shaker cognate l, isoform B", "tax_id": 7227, "disease": "spinocerebellar ataxia 19/22 (Disease Ontology:DOID:0050970); Brugada syndrome 9 (Disease Ontology:DOID:0110226)", "pathway": " (dme:Dmel_CG9262); (R-DME-1296072); (R-DME-5576894)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537572;20550966;2333511;2336395", "class_list": "", "function": "Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. May play a role in the nervous system and in the regulation of beating frequency in pacemaker cells., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A8JNV8;Q29R37;Q9VW11", "ec_number_list": [], "go_molecular_function": "GO:0005249 voltage-gated potassium channel activity;GO:0005250 A-type (transient outward) potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite;GO:0043204 perikaryon;GO:0045202 synapse", "go_biological_process": "GO:0008306 associative learning;GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0007268 chemical synaptic transmission;GO:0006813 potassium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P17971-2", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18053-1", "uniprot_id": [ { "id": "PSA4_DROME", "url": "https://www.uniprot.org/uniprot/P18053", "type": "external" } ], "mass": 29412.0, "length": 264, "protein_name": "Proteasome subunit alpha type-4", "gene_name": "Prosalpha3", "organism": "Fruit fly", "refseq_name": "proteasome alpha3 subunit", "refseq_ac": [ { "id": "NP_476691", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476691", "type": "external" } ], "gene_names_uniprotkb": "Prosalpha3; CG9327; PROS-29; Pros29", "gene_names_refseq": "Alpha-3; CG9327; Dmel\\CG9327; PROS-29; PSB3_DROME; Pros-alpha3; Pros20S-alpha3; Pros29; Prosalpha3; alpha-3; alpha3_dm; alpha3; pros29; prosalpha3", "protein_names_uniprotkb": "Proteasome subunit alpha type-4; PROS-Dm29; Proteasome 29 kDa subunit", "protein_names_refseq": "20s proteasome; CG9327-PA; Prosalpha3-PA; alpha-subunit of 20S proteasome; alpha3; proteasome 20S alpha3 subunit; proteasome 29kD subunit; proteasome alpha3 subunit; proteasome subunit alpha-type 4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9327); (R-DME-1169091); (R-DME-1234176); (R-DME-1236974); (R-DME-1236978); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-2467813); (R-DME-2871837); (R-DME-350562); (R-DME-382556); (R-DME-450408); (R-DME-4608870); (R-DME-4641257); (R-DME-4641258); (R-DME-5358346); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5632684); (R-DME-5658442); (R-DME-5676590); (R-DME-5689603); (R-DME-5689880); (R-DME-68867); (R-DME-68949); (R-DME-69017); (R-DME-69601); (R-DME-75815); (R-DME-8854050); (R-DME-8939236); (R-DME-8939902); (R-DME-8941858); (R-DME-8948751); (R-DME-8951664); (R-DME-9020702); (R-DME-9755511); (R-DME-9762114); (R-DME-983168); (R-DME-9907900); (R-DME-9912633); (R-DME-9929491); (R-DME-9932298); (R-DME-9954709)", "pathway_count": 50, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;15952742;23622245;2374736", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W2N9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P18053-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18105-1", "uniprot_id": [ { "id": "NOD_DROME", "url": "https://www.uniprot.org/uniprot/P18105", "type": "external" } ], "mass": 73908.0, "length": 666, "protein_name": "Kinesin-like protein Nod", "gene_name": "nod", "organism": "Fruit fly", "refseq_name": "no distributive disjunction, isoform B", "refseq_ac": [ { "id": "NP_001285129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285129", "type": "external" } ], "gene_names_uniprotkb": "nod; CG1763; DmNod; Dmel\\CG1763; Dmel_CG1763; DnMod; KIF 22; KIF22; NODA; NOD; Nod; l(1)TW6", "gene_names_refseq": "CG1763; DmNod; Dmel\\CG1763; DnMod; KIF 22; KIF22; NOD; Nod; l(1)TW6; nod", "protein_names_uniprotkb": "Kinesin-like protein Nod", "protein_names_refseq": "CG1763-PB; Kinesin4C; No distributive disjunction; kinesin-10; kineskin-10; no distributive disjunction, isoform B; nod-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1763)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;1743485;17569856;17569867;2144792;25589440;26109356;26109357", "class_list": "", "function": "Required for the distributive chromosome segregation of non-exchange chromosomes during meiosis. May be a microtubule motor required to hold distributively 'paired' chromosomes at the metaphase plate until anaphase., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VYW9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0051010 microtubule plus-end binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0007143 female meiotic nuclear division;GO:0007018 microtubule-based movement;GO:0031116 positive regulation of microtubule polymerization;GO:0045132 meiotic chromosome segregation;GO:0007057 spindle assembly involved in female meiosis I", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P18105-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18431-2", "uniprot_id": [ { "id": "SGG_DROME", "url": "https://www.uniprot.org/uniprot/P18431", "type": "external" } ], "mass": 53872.0, "length": 514, "protein_name": "Protein kinase shaggy", "gene_name": "sgg", "organism": "Fruit fly", "refseq_name": "shaggy, isoform A", "refseq_ac": [ { "id": "NP_476714", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476714", "type": "external" } ], "gene_names_uniprotkb": "sgg; CG2621; gsk3; zw3", "gene_names_refseq": "CG2621; DMSGG3; DMZ3K25Z; Dm Zw3; Dmel\\CG2621; Dmsgg3; EG:155E2.3; EG:BACR7C10.8; GSK-3B; GSK-3beta; GSK-3; GSK3-beta; GSK3A; GSK3Beta; GSK3beta/SGG; GSK3betagr; GSK3beta; GSK3; GSKbeta; GSK; Gsk-3beta; Gsk-3; Gsk3-beta; Gsk3beta; Gsk3; SGG/GSK3b; SGG; SHAGGY; Sgg/Zw3/GSK3; Sgg; Shaggy; ZW-3; ZW3; Zw-3; Zw3-sh; Zw3/GSK3; Zw3[sgg]; Zw3; anon-WO03040301.254; gsk3; l(1)3Ba; l(1)G0055; l(1)G0183; l(1)G0263; l(1)G0335; l(1)zw3; sgG4; sgg-1; sgg-zw3; sgg/GSK3; sgg/zw3; sgg10; sgg39; sgg46; sgg; zw-3; zw3(sgg); zw3/GSK3beta; zw3/sgg; zw3[sgg]; zw3; zw[3]", "protein_names_uniprotkb": "Protein kinase shaggy; 2.7.11.1; Protein zeste-white 3", "protein_names_refseq": "CG2621-PA; GSK-3 kinase; GSK3betagr; Shaggy/Glycogen synthase kinase 3; Shaggy/Zeste-white-3/Glycogen synthase kinase 3beta; Zeste-white3; Zw3 kinase; glycogen synthase Kinase-3; glycogen synthase kinase 3Beta; glycogen synthase kinase 3; glycogen synthase kinase-3beta; saggy; sgg-PA; shaggy, isoform A; shaggy-zeste white 3; shaggy/zeste-white 3; zest-white 3; zeste white 3; zeste white-3; zeste white3; zeste-white 3; zestewhite-3", "tax_id": 7227, "disease": "diabetic encephalopathy (Disease Ontology:DOID:0050850); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); Parkinson's disease (Disease Ontology:DOID:14330); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); colon cancer (Disease Ontology:DOID:219); endometrial carcinoma (Disease Ontology:DOID:2871); substance-related disorder (Disease Ontology:DOID:303); bipolar disorder (Disease Ontology:DOID:3312); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); middle cerebral artery infarction (Disease Ontology:DOID:3525); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); vascular dementia (Disease Ontology:DOID:8725); degenerative disc disease (Disease Ontology:DOID:90); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (dme:Dmel_CG2621); (R-DME-195253); (R-DME-196299); (R-DME-209155); (R-DME-209159); (R-DME-209190); (R-DME-209214); (R-DME-209360); (R-DME-209387); (R-DME-209396); (R-DME-209413); (R-DME-209440); (R-DME-209461); (R-DME-3371453); (R-DME-432553); (R-DME-4641262); (R-DME-5610785); (R-DME-69601); (R-DME-9762114); (R-DME-9856649)", "pathway_count": 20, "publication_count": 88, "publication_id_list": "10073940;10102270;10196136;10409506;10421629;10457025;10458606;10477300;10557210;10731132;10731137;10825151;10838083;10846164;11090136;11336703;11430804;11440719;11912487;11914126;11927557;11955435;11955436;12000790;12122057;12231619;12432393;12442174;12447397;12537569;12537572;12563262;12636921;12663920;12781135;12944510;1335365;14636582;14636583;14731402;14759367;14966281;15063184;15143183;15269269;15300262;15459103;15563523;15592457;15598741;15616566;15691767;15875013;16041759;16299518;16319317;16326393;16341016;16386907;16410523;16570248;16630821;16949836;16987508;17077139;17418796;17925225;18327897;18593878;18815259;2113617;2118107;22421435;7481773;7529201;8382613;8467811;8596938;8600384;8898207;8906787;8906794;8938123;8990193;9215627;9482888;9601642;9674431", "class_list": "", "function": "Required for several developmental events such as syncytial blastoderm formation and embryonic segmentation. Is involved in transcriptional regulation. Required for arm phosphorylation. Wg signaling operates by inactivating the sgg repression of en autoactivation. Negatively controls the neuromuscular junction (NMJ) growth in presynaptic motoneurons. Plays a role in the regulation of microtubule dynamics and actin cytoskeleton during embryogenesis. Required for phosphorylation of sra in activated eggs. Essential for completion of meiosis, possibly by triggering calcineurin activation via sra phosphorylation. Phosphorylates microtubule-associated protein futsch in axons., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76881;P23646;Q27603;Q27604;Q27605;Q8MRF7;Q9NF42;Q9U094;Q9W4X3", "ec_number_list": [ { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.5", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0046959 habituation;GO:0070884 regulation of calcineurin-NFAT signaling cascade;GO:0007165 signal transduction;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 8.9, "record_id": "P18431-2", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18475-1", "uniprot_id": [ { "id": "TORSO_DROME", "url": "https://www.uniprot.org/uniprot/P18475", "type": "external" } ], "mass": 105201.0, "length": 923, "protein_name": "Tyrosine-protein kinase receptor torso", "gene_name": "tor", "organism": "Fruit fly", "refseq_name": "torso, isoform D", "refseq_ac": [ { "id": "NP_001097212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097212", "type": "external" } ], "gene_names_uniprotkb": "tor; CG1389", "gene_names_refseq": "CG1389; Dmel\\CG1389; TORSO; TOR; Torso; Tor; dTor; splc; tor", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor torso; 2.7.10.1", "protein_names_refseq": "CG1389-PD; spliced; tor-PD; torso, isoform D; torso", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1389)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;18327897;19965758;2927509;8423783", "class_list": "", "function": "Probable receptor tyrosine kinase which is required for determination of anterior and posterior terminal structures in the embryo (PubMed:2927509, PubMed:8423783). During postembryonic development, involved in the initiation of metamorphosis probably by inducing the production of ecdysone in response to prothoracicotropic hormone Ptth (PubMed:19965758). Binding to Ptth stimulates activation of canonical MAPK signaling leading to ERK phosphorylation (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 12, "predicted_n_glycosites": 12, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "A8DY54;A8DY56;Q9V4R2", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0040015 negative regulation of multicellular organism growth;GO:0035331 negative regulation of hippo signaling", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P18475-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18489-1", "uniprot_id": [ { "id": "SYB_DROME", "url": "https://www.uniprot.org/uniprot/P18489", "type": "external" } ], "mass": 16712.0, "length": 152, "protein_name": "Synaptobrevin", "gene_name": "Syb", "organism": "Fruit fly", "refseq_name": "synaptobrevin, isoform C", "refseq_ac": [ { "id": "NP_001137633", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137633", "type": "external" } ], "gene_names_uniprotkb": "Syb; CG12210", "gene_names_refseq": "21.15; CG12210; Dmel\\CG12210; END1-2; J; SYB; Syb; VAMP2; VAMP; Vamp; c-Syb; dVAMP; l(2)46CFq; l(2)46El; n-syb; syb; synaptobrevin", "protein_names_uniprotkb": "Synaptobrevin", "protein_names_refseq": "CG12210-PC; Syb-PC; VAMP3; Vesicle-associated membrane protein; complementation group J; synaptobrevin, isoform C; synaptobrevin", "tax_id": 7227, "disease": "spastic ataxia 1 (Disease Ontology:DOID:0050772); congenital myasthenic syndrome (Disease Ontology:DOID:3635)", "pathway": " (dme:Dmel_CG12210); (R-DME-181429); (R-DME-181430); (R-DME-199992); (R-DME-210500); (R-DME-212676); (R-DME-264642); (R-DME-432720); (R-DME-432722); (R-DME-449836); (R-DME-6798695); (R-DME-6811440); (R-DME-8856825); (R-DME-8856828); (R-DME-888590); (R-DME-8980692); (R-DME-9013149); (R-DME-9013406); (R-DME-9013407); (R-DME-9013423); (R-DME-9035034); (R-DME-9609523)", "pathway_count": 22, "publication_count": 9, "publication_id_list": "10731132;12364587;12537572;23353890;2560644;26974662;27323327;8229205;8406010", "class_list": "", "function": "Involved in the targeting and/or fusion of transport vesicles to their target membrane., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B7YZD5;B7YZD6;Q3HKB4;Q8MKX1;Q9V5I6", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030672 synaptic vesicle membrane;GO:0008021 synaptic vesicle;GO:0031201 SNARE complex", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0031340 positive regulation of vesicle fusion;GO:0007269 neurotransmitter secretion;GO:0006906 vesicle fusion;GO:0016081 synaptic vesicle docking", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P18489-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20007-1", "uniprot_id": [ { "id": "PCKG_DROME", "url": "https://www.uniprot.org/uniprot/P20007", "type": "external" } ], "mass": 71129.0, "length": 647, "protein_name": "Phosphoenolpyruvate carboxykinase [GTP]", "gene_name": "Pepck1", "organism": "Fruit fly", "refseq_name": "phosphoenolpyruvate carboxykinase 1", "refseq_ac": [ { "id": "NP_523784", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523784", "type": "external" } ], "gene_names_uniprotkb": "Pepck1; CG17725; Pepck; ZDF4", "gene_names_refseq": "143299_at; CG10924; CG17725; Dmel\\CG17725; Dromel_CG17725_FBtr0086701_pepck_mORF; PEPCK1; PEPCK; Pepck1; Pepck; dPEPCK; pepck1; pepck", "protein_names_uniprotkb": "Phosphoenolpyruvate carboxykinase [GTP]; 4.1.1.32; Phosphoenolpyruvate carboxykinase 1", "protein_names_refseq": "CG17725-PA; Pepck1-PA; Phosphoenolpyruvate-carboxykinase; phosphoenol pyruvate carboxykinase; phosphoenol-pyruvate carboxykinase; phosphoenolpyruvate carboxy kinase; phosphoenolpyruvate carboxykinase 1; phosphoenolpyruvate carboxykinase", "tax_id": 7227, "disease": "metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG17725); (R-DME-70263)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;3114718", "class_list": "", "function": "Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1ZB97;Q53YF8;Q9V8J0", "ec_number_list": [ { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0030145 manganese ion binding;GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046327 glycerol biosynthetic process from pyruvate;GO:0042594 response to starvation;GO:0071333 cellular response to glucose stimulus;GO:0006094 gluconeogenesis;GO:0006107 oxaloacetate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P20007-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20028-1", "uniprot_id": [ { "id": "RPA2_DROME", "url": "https://www.uniprot.org/uniprot/P20028", "type": "external" } ], "mass": 128444.0, "length": 1129, "protein_name": "DNA-directed RNA polymerase I subunit RPA2", "gene_name": "Polr1B", "organism": "Fruit fly", "refseq_name": "RNA polymerase I subunit B", "refseq_ac": [ { "id": "NP_476708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476708", "type": "external" } ], "gene_names_uniprotkb": "Polr1B; CG4033; RP135; RpI135", "gene_names_refseq": "CG4033; DmRP135; Dmel\\CG4033; Polr1B; RP135; RPA135; RPI135; RpI135; RpIII135; Rpl135; l(2)k16513", "protein_names_uniprotkb": "DNA-directed RNA polymerase I subunit RPA2; 2.7.7.6; RNA polymerase I subunit 2; RNA polymerase I subunit B; RPA135", "protein_names_refseq": "CG4033-PA; Polr1B-PA; RNA polymerase I 135kD subunit; RNA polymerase I subunit B; RNA polymerase I", "tax_id": 7227, "disease": "Treacher Collins syndrome 4 (Disease Ontology:DOID:0080792); Treacher Collins syndrome (Disease Ontology:DOID:2908)", "pathway": " (dme:Dmel_CG4033); (R-DME-73762); (R-DME-73772)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;2482932;25858587", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPP3", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0032549 ribonucleoside binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005736 RNA polymerase I complex", "go_biological_process": "GO:0006360 transcription by RNA polymerase I;GO:0006362 transcription elongation by RNA polymerase I;GO:0006361 transcription initiation at RNA polymerase I promoter;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P20028-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20227-1", "uniprot_id": [ { "id": "TBP_DROME", "url": "https://www.uniprot.org/uniprot/P20227", "type": "external" } ], "mass": 38451.0, "length": 353, "protein_name": "TATA-box-binding protein", "gene_name": "Tbp", "organism": "Fruit fly", "refseq_name": "TATA binding protein", "refseq_ac": [ { "id": "NP_523805", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523805", "type": "external" } ], "gene_names_uniprotkb": "Tbp; BTF1; CG9874; TFIID", "gene_names_refseq": "CG9874; Dmel\\CG9874; RBP; TBP38; TBP; TFIIDtau; TFIID; Tbp; TfIID; dTBP; dTFIID; dTbp; dtbp; tbp", "protein_names_uniprotkb": "TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit", "protein_names_refseq": "42kDa polypeptide; CG9874-PA; TATA binding protein; TATA box binding protein; TATA box-binding protein; TATA-binding protein; TATA-box binding protein; Tbp-PA", "tax_id": 7227, "disease": "sleep apnea (Disease Ontology:DOID:0050847); spinocerebellar ataxia 17 (Disease Ontology:DOID:0050967); late onset Parkinson's disease (Disease Ontology:DOID:0060892); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); schizophrenia (Disease Ontology:DOID:5419); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG9874); (R-DME-674695); (R-DME-6804756); (R-DME-6807505); (R-DME-73772); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-76042); (R-DME-76061); (R-DME-76066); (R-DME-9018519)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537569;12537572;2123550;2194666;7875589;8178153;8224849;8247000;8276241;8464492", "class_list": "", "function": "General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W2D8", "ec_number_list": [], "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0140296 general transcription initiation factor binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0001091 RNA polymerase II general transcription initiation factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex;GO:0000126 transcription factor TFIIIB complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0042789 mRNA transcription by RNA polymerase II;GO:0006383 transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P20227-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20240-1", "uniprot_id": [ { "id": "OTE_DROME", "url": "https://www.uniprot.org/uniprot/P20240", "type": "external" } ], "mass": 46584.0, "length": 424, "protein_name": "Otefin", "gene_name": "Ote", "organism": "Fruit fly", "refseq_name": "otefin", "refseq_ac": [ { "id": "NP_476664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476664", "type": "external" } ], "gene_names_uniprotkb": "Ote; CG5581", "gene_names_refseq": "CG5581; Dmel\\CG5581; Ote; hal; otefin; ote", "protein_names_uniprotkb": "Otefin; LEM domain-containing protein Otefin", "protein_names_refseq": "CG5581-PA; Ote-PA; emerin; halted; haulted; otefin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5581)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12537569;12537572;16439308;18327897;18410727;2186029;22751930;23806619;24700158;2517292;27174470;32923640;8999964;9199347;9632815", "class_list": "", "function": "Inner nuclear membrane protein (PubMed:18410727, PubMed:2186029, PubMed:22751930, PubMed:9199347). Involved in the attachment of membrane vesicles to chromatin during nuclear assembly, and is probably required for centrosome maturation and cell cycle progression during mitosis (PubMed:22751930, PubMed:9199347). Essential for differentiation of certain tissues and the maintenance of progenitor cell populations (PubMed:18410727, PubMed:23806619, PubMed:24700158, PubMed:27174470). Required for the differentiation and maintenance of male and female germline stem cells (GSCs), as well as the maintenance of somatic cells in the GSC niche (PubMed:18410727, PubMed:23806619, PubMed:27174470). This role is likely to be independent of the BMP (Dpp) pathway that negatively regulates bam transcription during GSC differentiation (PubMed:18410727, PubMed:23806619). During development, plays essential and redundant functions with the other LEM domain proteins; bocks and MAN1 (PubMed:24700158). Also has a redundant but important role with bocks during larval development (PubMed:24700158)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V8E5", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005641 nuclear envelope lumen;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0031468 nuclear membrane reassembly;GO:0051301 cell division;GO:0045892 negative regulation of DNA-templated transcription;GO:0030513 positive regulation of BMP signaling pathway;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P20240-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20350-1", "uniprot_id": [ { "id": "RHOM_DROME", "url": "https://www.uniprot.org/uniprot/P20350", "type": "external" } ], "mass": 39330.0, "length": 355, "protein_name": "Protein rhomboid", "gene_name": "rho", "organism": "Fruit fly", "refseq_name": "rhomboid, isoform B", "refseq_ac": [ { "id": "NP_001261255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261255", "type": "external" } ], "gene_names_uniprotkb": "rho; CG1004; Ve", "gene_names_refseq": "CG1004; DMRHOa; DMRHOb; DMRHO; DRORHO; DmRho1; Dmel\\CG1004; Dmel\\rho; Dmrho; RHOb; RHO; Rho-1; Rho1; Rho; Ve; iks; rho-1; rho1; rhomboid/veinlet; rhom; rho; ve", "protein_names_uniprotkb": "Protein rhomboid; 3.4.21.105; Protein veinlet", "protein_names_refseq": "CG1004-PB; RHOMBOID; Rhomboid-I; rho-PB; rhomboid 1; rhomboid, isoform B; rhomboid-1; rhomboid/veinlet; rhomboid1", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG1004)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;11672525;12537572;2110920;21439629", "class_list": "", "function": "Acts early in embryonic development to establish position along the dorsoventral axis and then again later to specify the fate of neuronal precursor cells. Involved in EGF receptor signaling; cleaves Spitz to release the active growth factor., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W0F2", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0045177 apical part of cell", "go_biological_process": "GO:0007409 axonogenesis;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0016485 protein processing;GO:0048149 behavioral response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P20350-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20659-1", "uniprot_id": [ { "id": "TRX_DROME", "url": "https://www.uniprot.org/uniprot/P20659", "type": "external" } ], "mass": 400098.0, "length": 3726, "protein_name": "Histone-lysine N-methyltransferase trithorax", "gene_name": "trx", "organism": "Fruit fly", "refseq_name": "trithorax, isoform E", "refseq_ac": [ { "id": "NP_001014621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014621", "type": "external" } ], "gene_names_uniprotkb": "trx; CG8651; KMT2A", "gene_names_refseq": "4720; 4733; CG8651; DMTRXIII; Dmel\\CG8651; NR0A5; R-bx; Rg-bx; TRX; TrX; Trx-C; Trx-G; Trx/MLL; TrxG; Trx; l(3)bx[v]; l(3)j14A6; l(3)j3A2; l(3)s5452; tqrx; trx-g; trxG; trxI and trxII; trx", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase trithorax; 2.1.1.-; 2.1.1.355; Cysteine methyltransferase KMT2A; Lysine N-methyltransferase 2A", "protein_names_refseq": "CG8651-PE; regulator of bithorax; trithorax, isoform E; trithorax; trx-PE", "tax_id": 7227, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); dystonia 28, childhood-onset (Disease Ontology:DOID:0060936); autosomal dominant intellectual developmental disorder 68 (Disease Ontology:DOID:0061041); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682); transient cerebral ischemia (Disease Ontology:DOID:224); cervical cancer (Disease Ontology:DOID:4362); myelofibrosis (Disease Ontology:DOID:4971); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG8651); (R-DME-201722); (R-DME-8936459); (R-DME-8939236); (R-DME-9772755); (R-DME-9909649)", "pathway_count": 6, "publication_count": 14, "publication_id_list": "10454589;10656681;10731132;12408863;12537569;12537572;2107543;24235145;25310983;26957542;40245499;7924996;7958911;8555104", "class_list": "", "function": "Histone methyltransferase that methylates 'Lys-4' of histone H3 (H3K4me) (PubMed:12408863). H3K4me represents a specific tag for epigenetic transcriptional activation (PubMed:12408863). Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes (PubMed:2107543, PubMed:7958911). Acts as an activator of BX-C (PubMed:7924996). Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo (PubMed:25310983, PubMed:7924996). Also has auto-methylation activity on Cys-3641 (PubMed:24235145)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 13, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "A4V2V9;A4V2W0;Q27255;Q27327;Q8INF9;Q960R2;Q9VFL1", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" }, { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" }, { "id": "3.4.19.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.5", "type": "external" }, { "id": "3.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.1", "type": "external" }, { "id": "3.4.25.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.-", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0008023 transcription elongation factor complex;GO:0035097 histone methyltransferase complex;GO:0000123 histone acetyltransferase complex;GO:0044665 MLL1/2 complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P20659-1", "record_type": "protein", "filter_code": "0000000.0100111.001000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21461-1", "uniprot_id": [ { "id": "SINA_DROME", "url": "https://www.uniprot.org/uniprot/P21461", "type": "external" } ], "mass": 33707.0, "length": 314, "protein_name": "E3 ubiquitin-protein ligase sina", "gene_name": "sina", "organism": "Fruit fly", "refseq_name": "seven in absentia, isoform C", "refseq_ac": [ { "id": "NP_001287089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287089", "type": "external" } ], "gene_names_uniprotkb": "sina; CG9949; Dmel\\CG9949; Dmel_CG9949; SIAH; SINA; Sina; anon-EST:fe2H7; sia", "gene_names_refseq": "CG9949; Dmel\\CG9949; SIAH; SINA; Sina; anon-EST:fe2H7; sia; sina", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase sina; 2.3.2.27; RING-type E3 ubiquitin transferase sina; Seven in absentia protein", "protein_names_refseq": "CG9949-PC; anon-fast-evolving-2H7; seven in absentia, isoform C; seven in absentia; seven in absenti; seven-in-absentia; sina-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9949); (R-DME-5689880); (R-DME-983168)", "pathway_count": 3, "publication_count": 19, "publication_id_list": "10731132;11032805;11526076;12215542;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18160715;2146028;25589440;26109356;26109357;9267026;9267027", "class_list": "", "function": "E3 ubiquitin-protein ligase that is required for specification of R7 photoreceptor cell fate in the eye by mediating the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk). E3 Ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Acts via the formation of a complex with ebi and phyl that ubiquitinates the transcription repressor ttk, a general inhibitor of photoreceptor differentiation, in a subset of photoreceptor cells in the eye, leading to the differentiation of cells into neurons. Also involved in external sensory organ development., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V214;Q9VVB0", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.24", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0007601 visual perception;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0010498 proteasomal protein catabolic process;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P21461-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21520-1", "uniprot_id": [ { "id": "SCA_DROME", "url": "https://www.uniprot.org/uniprot/P21520", "type": "external" } ], "mass": 90119.0, "length": 799, "protein_name": "Protein scabrous", "gene_name": "sca", "organism": "Fruit fly", "refseq_name": "scabrous, isoform A", "refseq_ac": [ { "id": "NP_476710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476710", "type": "external" } ], "gene_names_uniprotkb": "sca; CG17579", "gene_names_refseq": "AAA28880; AAF58455; CG17579; Dmel\\CG17579; FBpp0086968; FBpp0086969; Sca1b; Sca; anon-EST:Liang-38; clone 38; mAb sca1; sca", "protein_names_uniprotkb": "Protein scabrous", "protein_names_refseq": "CG17579-PA; Fibrinogen-related protein; sca-PA; scabrous, isoform A; scabrous", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG17579)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;12756167;2175046", "class_list": "", "function": "Involved in regulation of neurogenesis. May encode a lateral inhibitor of R8 differentiation. In conjunction with Gp150, promotes Notch activation in response to Delta by regulating acquisition of insensitivity to Delta in a subset of cells., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q0E998;Q8MQI8;Q9V6G9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0005770 late endosome", "go_biological_process": "GO:0097305 response to alcohol;GO:0048749 compound eye development;GO:0007219 Notch signaling pathway;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P21520-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21521-1", "uniprot_id": [ { "id": "SY65_DROME", "url": "https://www.uniprot.org/uniprot/P21521", "type": "external" } ], "mass": 53260.0, "length": 474, "protein_name": "Synaptotagmin 1", "gene_name": "Syt1", "organism": "Fruit fly", "refseq_name": "synaptotagmin 1, isoform F", "refseq_ac": [ { "id": "NP_001259965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259965", "type": "external" } ], "gene_names_uniprotkb": "Syt1; 2L17; CG3139; D. Syt I; DSYT1; DSYT2; DSYT; DSypt1; DSypt; DSyt1; DSyt; Dmel\\CG3139; Dmel_CG3139; Droso1; Dsyt2; STY1; SYT I; SYT1; SYT; Syt 1; Syt I; Syt-1; SytI; Syt; dSYT; dSyt1; dsyt1; dsytI; l(2)23AB1; l(2)23Ba; l(2)k05909; syn; syt 1; syt I; syt-1; syt1; sytI; syt", "gene_names_refseq": "2L17; CG3139; D. Syt I; DSYT1; DSYT2; DSYT; DSypt1; DSypt; DSyt1; DSyt; Dmel\\CG3139; Droso1; Dsyt2; STY1; SYT I; SYT1; SYT; Syt 1; Syt I; Syt-1; Syt1; SytI; Syt; dSYT; dSyt1; dsyt1; dsytI; l(2)23AB1; l(2)23Ba; l(2)k05909; syn; syt 1; syt I; syt-1; syt1; sytI; syt", "protein_names_uniprotkb": "Synaptotagmin 1; p65", "protein_names_refseq": "CG3139-PF; Synaptotagmin-1; Synaptotagmin-I; Synaptotagmin1; SynaptotagminI; Syt I; Syt1-PF; synaptoptagmin 1; synaptotagmin 1, isoform F; synaptotagmin 1; synaptotagmin I", "tax_id": 7227, "disease": "congenital myasthenic syndrome 7 (Disease Ontology:DOID:0110659); congenital myasthenic syndrome (Disease Ontology:DOID:3635); neuromuscular junction disease (Disease Ontology:DOID:439)", "pathway": " (dme:Dmel_CG3139); (R-DME-181429); (R-DME-181430); (R-DME-210500); (R-DME-212676); (R-DME-264642); (R-DME-8856825); (R-DME-8856828); (R-DME-888590)", "pathway_count": 9, "publication_count": 16, "publication_id_list": "10731132;11069931;12537568;12537569;12537572;12537573;12537574;12907802;16110336;17569856;17569867;1840599;25589440;26109356;26109357;29568072", "class_list": "", "function": "May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V023;M9PB17;M9PE99;Q7KU16;Q86NN2;Q8MRR8;Q9VQG7;Q9VQG8", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0000149 SNARE binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0031594 neuromuscular junction;GO:0043195 terminal bouton", "go_biological_process": "GO:0060024 rhythmic synaptic transmission;GO:0050803 regulation of synapse structure or activity;GO:0007268 chemical synaptic transmission;GO:0016192 vesicle-mediated transport;GO:0031340 positive regulation of vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P21521-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21914-1", "uniprot_id": [ { "id": "SDHB_DROME", "url": "https://www.uniprot.org/uniprot/P21914", "type": "external" } ], "mass": 33741.0, "length": 297, "protein_name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "gene_name": "SdhB", "organism": "Fruit fly", "refseq_name": "succinate dehydrogenase, subunit B (iron-sulfur)", "refseq_ac": [ { "id": "NP_477101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477101", "type": "external" } ], "gene_names_uniprotkb": "SdhB; CG3283; SDH", "gene_names_refseq": "CG3283; CII-SDHB; DHSB; Dmel\\CG3283; Ip; SDH-B; SDH-IP; SDH-Ip; SDHb; SDH; SdhB; Sdhb; sdhB", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; 1.3.5.1; Ip; Iron-sulfur subunit of complex II", "protein_names_refseq": "CG3283-PA; COMPLEX II: iron-sulfur subunit; SdhB-PA; iron-sulfur protein subunit of succinate dehydrogenase; succinate dehydrogenase B; succinate dehydrogenase Iron-sulfur protein; succinate dehydrogenase [ubiquinone] iron-sulfur protein; succinate dehydrogenase complex subunit B; succinate dehydrogenase iron protein; succinate dehydrogenase subunit b; succinate dehydrogenase, subunit B (iron-sulfur)", "tax_id": 7227, "disease": "pheochromocytoma (Disease Ontology:DOID:0050771); paraganglioma (Disease Ontology:DOID:0050773); mitochondrial complex II deficiency (Disease Ontology:DOID:0060537); pheochromocytoma/paraganglioma syndrome 4 (Disease Ontology:DOID:0061219); Carney-Stratakis syndrome (Disease Ontology:DOID:0080533); mitochondrial encephalomyopathy (Disease Ontology:DOID:890); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (dme:Dmel_CG3283); (R-DME-71403)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;2494655;7958999", "class_list": "", "function": "Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V9A0", "ec_number_list": [ { "id": "1.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.5.1", "type": "external" }, { "id": "1.3.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.-.-", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0022904 respiratory electron transport chain;GO:0009060 aerobic respiration;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P21914-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22293-1", "uniprot_id": [ { "id": "SUS_DROME", "url": "https://www.uniprot.org/uniprot/P22293", "type": "external" } ], "mass": 143840.0, "length": 1325, "protein_name": "Protein suppressor of sable", "gene_name": "su(sable)", "organism": "Fruit fly", "refseq_name": "suppressor of sable, isoform C", "refseq_ac": [ { "id": "NP_001284753", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284753", "type": "external" } ], "gene_names_uniprotkb": "su(sable); CG6222; Dmel\\CG6222; Dmel_CG6222; EG:115C2.3; su(s); su-s; su-v; su[2]-s", "gene_names_refseq": "CG6222; Dmel\\CG6222; EG:115C2.3; su(s); su(sable); su-s; su-v; su[2]-s", "protein_names_uniprotkb": "Protein suppressor of sable", "protein_names_refseq": "CG6222-PC; su(sable)-PC; suppressor of sable, isoform C; suppressor of sable; suppressor-of-sable", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6222); (R-DME-6807505); (R-DME-9930044)", "pathway_count": 3, "publication_count": 21, "publication_id_list": "10731132;10731137;11027289;12537568;12537569;12537572;12537573;12537574;15082769;16110336;1703632;17569856;17569867;18327897;1963868;19687295;25589440;26109356;26109357;26577379;9121479", "class_list": "", "function": "RNA-binding protein that suppresses transcription of some RNAs (PubMed:11027289, PubMed:15082769, PubMed:1703632, PubMed:19687295, PubMed:26577379, PubMed:9121479). Together with Wdr82, part of a transcription termination checkpoint that promotes transcription termination of RNAs and their subsequent degradation by the nuclear exosome (PubMed:26577379). Promotes transcription termination of aberrant RNAs, transcripts from genes containing a transposon inserted at their very 5' end or RNAs from heat-shock-inducible repetitive element (PubMed:1703632, PubMed:19687295, PubMed:26577379). Binds RNA preferentially at a sequence that resembles a cryptic 5'-splice site (PubMed:9121479)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O77427;Q8SYG7", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005700 polytene chromosome", "go_biological_process": "GO:0032785 negative regulation of DNA-templated transcription, elongation;GO:0045892 negative regulation of DNA-templated transcription;GO:0006353 DNA-templated transcription termination;GO:0071027 nuclear RNA surveillance", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P22293-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22812-1", "uniprot_id": [ { "id": "TUBE_DROME", "url": "https://www.uniprot.org/uniprot/P22812", "type": "external" } ], "mass": 49776.0, "length": 462, "protein_name": "Protein Tube", "gene_name": "tub", "organism": "Fruit fly", "refseq_name": "tube", "refseq_ac": [ { "id": "NP_001189164", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189164", "type": "external" } ], "gene_names_uniprotkb": "tub; CG10520; tube", "gene_names_refseq": "CG10520; Dmel\\CG10520; TUBE; Tube; tub", "protein_names_uniprotkb": "Protein Tube", "protein_names_refseq": "CG10520-PC; tub-PC; tube", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10520); (R-DME-209442); (R-DME-214842); (R-DME-214844); (R-DME-214862); (R-DME-214863); (R-DME-214869); (R-DME-214874)", "pathway_count": 8, "publication_count": 33, "publication_id_list": "10072384;10512628;10589682;10660298;10731132;11296245;11350927;11493599;11532919;11934858;12493753;12537569;12537572;12872120;14667416;14685264;15197269;15795223;16399077;16782008;16996061;17324925;18347020;1899484;7527496;7635064;8026333;8253071;8948598;9367441;9405646;9533958;9806920", "class_list": "", "function": "Plays an essential role in the Tl receptor signaling pathway that establishes embryonic dorsoventral polarity; the signal directs import of dl into ventral and ventrolateral nuclei, thereby establishing dorsoventral polarity. Tub recruits pll to the plasma membrane and protein-protein interaction activates pll. Also has a role in pupal pattern formation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B7Z0I9;E8NH30;Q9VN15", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:1990782 protein tyrosine kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0009953 dorsal/ventral pattern formation;GO:0031663 lipopolysaccharide-mediated signaling pathway;GO:0009620 response to fungus", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "P22812-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23757-1", "uniprot_id": [ { "id": "POXM_DROME", "url": "https://www.uniprot.org/uniprot/P23757", "type": "external" } ], "mass": 38388.0, "length": 370, "protein_name": "Paired box pox-meso protein", "gene_name": "Poxm", "organism": "Fruit fly", "refseq_name": "Pox meso", "refseq_ac": [ { "id": "NP_001036687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036687", "type": "external" } ], "gene_names_uniprotkb": "Poxm; CG9610; POX-M", "gene_names_refseq": "CG9610; Dmel\\CG9610; P29; POXM; Pox-m; Poxm; meso; poxm", "protein_names_uniprotkb": "Paired box pox-meso protein; Paired box mesodermal protein", "protein_names_refseq": "CG9610-PC; Pox meso; Pox-meso; Poxm-PC; paired box mesodermal; paired box-meso", "tax_id": 7227, "disease": "tooth agenesis (Disease Ontology:DOID:0050591); branchiootorenal syndrome (Disease Ontology:DOID:14702)", "pathway": " (dme:Dmel_CG9610)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;17942482;2573516", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4K7U1;Q1RL17;Q9VHS5", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048813 dendrite morphogenesis;GO:0007526 larval somatic muscle development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P23757-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23758-1", "uniprot_id": [ { "id": "POXN_DROME", "url": "https://www.uniprot.org/uniprot/P23758", "type": "external" } ], "mass": 44329.0, "length": 425, "protein_name": "Paired box pox-neuro protein", "gene_name": "Poxn", "organism": "Fruit fly", "refseq_name": "Pox neuro, isoform B", "refseq_ac": [ { "id": "NP_001261016", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261016", "type": "external" } ], "gene_names_uniprotkb": "Poxn; CG8246; pox-n", "gene_names_refseq": "CG8246; Dmel\\CG8246; P4; Pox-n; Poxn1; Poxn; neuro; pox-n; poxn", "protein_names_uniprotkb": "Paired box pox-neuro protein; Paired box neuronal protein", "protein_names_refseq": "CG8246-PB; Pox neuro, isoform B; Poxn-PB; paired box neural; paired box-neuro; pox neuro; pox-neural; pox-neuro", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8246); (R-DME-8939245)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537572;1348214;2573516;8292359;9183748", "class_list": "", "function": "Transcriptional regulator that specifies poly-innervated organs (chemosensory bristle). Also controls the number of neurons., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9V7F3", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0008049 male courtship behavior;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P23758-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23803-1", "uniprot_id": [ { "id": "ODD_DROME", "url": "https://www.uniprot.org/uniprot/P23803", "type": "external" } ], "mass": 44626.0, "length": 392, "protein_name": "Protein odd-skipped", "gene_name": "odd", "organism": "Fruit fly", "refseq_name": "odd skipped", "refseq_ac": [ { "id": "NP_722922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_722922", "type": "external" } ], "gene_names_uniprotkb": "odd; CG3851", "gene_names_refseq": "CG3851; Dmel\\CG3851; ODD; Odd; l(2)01863; odd; ods", "protein_names_uniprotkb": "Protein odd-skipped", "protein_names_refseq": "CG3851-PA; odd paired; odd skipped; odd-PA; odd-skipped; oddskipped", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3851)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;10960790;12537569;12537572;14597202;2120051;7750646;9806933", "class_list": "", "function": "Pair-rule protein that determines both the size and polarity of even-numbered as well as odd-numbered parasegments during embryogenesis. DNA-binding transcription factor that acts primarily as a transcriptional repressor but can also function as a transcriptional activator, depending on the stage of development and spatial restrictions. May function redundantly with odd and drm in leg joint formation during the larval stages, acting downstream of Notch activation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQS9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048619 embryonic hindgut morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P23803-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25007-1", "uniprot_id": [ { "id": "PPIA_DROME", "url": "https://www.uniprot.org/uniprot/P25007", "type": "external" } ], "mass": 24666.0, "length": 227, "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Cyp1", "organism": "Fruit fly", "refseq_name": "cyclophilin 1", "refseq_ac": [ { "id": "NP_523366", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523366", "type": "external" } ], "gene_names_uniprotkb": "Cyp1; CG9916; Cyp-1", "gene_names_refseq": "BcDNA:GM09255; CG9916; Cpy1; CyP-1; CyP1; Cyp-1; Cyp1; Dmel\\CG9916; cyp-1; cyp1", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase; 5.2.1.8; Cyclophilin; Cyclosporin A-binding protein; PPIase; Rotamase", "protein_names_refseq": "CG9916-PA; Cyp1-PA; Peptidyl-prolyl cis-trans isomerase; cyclophilin 1; cyclophilin1; cyclophilin; peptidylprolyl isomerase F", "tax_id": 7227, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); Bell's palsy (Disease Ontology:DOID:12506); aggressive periodontitis (Disease Ontology:DOID:1474); epilepsy (Disease Ontology:DOID:1826); cholangiocarcinoma (Disease Ontology:DOID:4947); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (dme:Dmel_CG9916)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;1707759;18327897;8500545", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VXH8", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P25007-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25008-1", "uniprot_id": [ { "id": "CCNC_DROME", "url": "https://www.uniprot.org/uniprot/P25008", "type": "external" } ], "mass": 31292.0, "length": 267, "protein_name": "Cyclin-C", "gene_name": "CycC", "organism": "Fruit fly", "refseq_name": "cyclin C", "refseq_ac": [ { "id": "NP_476848", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476848", "type": "external" } ], "gene_names_uniprotkb": "CycC; CG7281; CLND", "gene_names_refseq": "CCNC; CG1C_DROME; CG7281; CYCC; Cln3; Cyc-C; CycC; DmcycC; Dmel\\CG7281; SRB11; cycC; cyclinC; dCycC; dTRAP33", "protein_names_uniprotkb": "Cyclin-C", "protein_names_refseq": "CG7281-PA; CycC-PA; cyclin C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7281); (R-DME-2173796); (R-DME-9841922)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537572;17290221;1833067;1836192;8730095", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase Cdk8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. Required for leg and eye development and macrochaete specification or differentiation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFF1", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:1990508 CKM complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034472 snRNA 3'-end processing;GO:0045498 sex comb development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25008-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25171-1", "uniprot_id": [ { "id": "RCC1_DROME", "url": "https://www.uniprot.org/uniprot/P25171", "type": "external" } ], "mass": 58851.0, "length": 547, "protein_name": "Regulator of chromosome condensation", "gene_name": "Rcc1", "organism": "Fruit fly", "refseq_name": "regulator of chromosome condensation 1, isoform A", "refseq_ac": [ { "id": "NP_523943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523943", "type": "external" } ], "gene_names_uniprotkb": "Rcc1; Bj1; CG10480", "gene_names_refseq": "BJ1; Bj1; CG10480; CG18640 (Bj1); Dmel\\CG10480; RCC1; RanGEF; Rcc1; bj1; dRCC1; inxs; sdt", "protein_names_uniprotkb": "Regulator of chromosome condensation; Chromatin-binding protein Bj1; Regulator of chromosome condensation 1 ortholog", "protein_names_refseq": "Bj1 protein; CG10480-PA; Rcc1-PA; in excess; regulator of chromosome condensation 1 ortholog; regulator of chromosome condensation 1, isoform A; side-out", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10480); (R-DME-9615933)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12121620;12537569;12537572;18327897;2022188;2022190;40245499", "class_list": "", "function": "Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to chromatin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4V1J1;Q9VRR5", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000793 condensed chromosome", "go_biological_process": "GO:0046822 regulation of nucleocytoplasmic transport;GO:0051301 cell division;GO:0007417 central nervous system development;GO:0007346 regulation of mitotic cell cycle;GO:0050767 regulation of neurogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25171-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P26675-1", "uniprot_id": [ { "id": "SOS_DROME", "url": "https://www.uniprot.org/uniprot/P26675", "type": "external" } ], "mass": 177934.0, "length": 1596, "protein_name": "Protein son of sevenless", "gene_name": "Sos", "organism": "Fruit fly", "refseq_name": "Son of sevenless", "refseq_ac": [ { "id": "NP_476597", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476597", "type": "external" } ], "gene_names_uniprotkb": "Sos; CG7793", "gene_names_refseq": "2.3; 34Ea; BG:DS00941.4; CG7793; Dmel\\CG7793; E(sev)2A; E(var)189; EC2-5; EK2-8; EY2-3; SOS; SoS; Sos1; Sos; Su(tor)2-2; br24; br25; dSos; dme-SOS; l(2)34Ea; l(2)Sos; l(2)br24; l(2)br25; l(2)k05224; l(2)k06321; sos", "protein_names_uniprotkb": "Protein son of sevenless", "protein_names_refseq": "CG7793-PA; Son of sevenless; Son-of-sevenless; Sos-PA; lethal 24 in the black-reduced region; lethal 25 in the black-reduced region", "tax_id": 7227, "disease": "gingival fibromatosis (Disease Ontology:DOID:0060466); Noonan syndrome 4 (Disease Ontology:DOID:0060582); Noonan syndrome 9 (Disease Ontology:DOID:0060587); prostate cancer (Disease Ontology:DOID:10283); atrial heart septal defect (Disease Ontology:DOID:1882); brain ischemia (Disease Ontology:DOID:2316); Noonan syndrome (Disease Ontology:DOID:3490); cerebral infarction (Disease Ontology:DOID:3526); cervical cancer (Disease Ontology:DOID:4362); pulmonary valve stenosis (Disease Ontology:DOID:6420)", "pathway": " (dme:Dmel_CG7793); (R-DME-112412); (R-DME-1250347); (R-DME-1433557); (R-DME-1433559); (R-DME-167044); (R-DME-179812); (R-DME-180336); (R-DME-186763); (R-DME-193648); (R-DME-1963640); (R-DME-210993); (R-DME-2179392); (R-DME-2424491); (R-DME-2428933); (R-DME-2730905); (R-DME-2871796); (R-DME-2871809); (R-DME-375165); (R-DME-416482); (R-DME-5654688); (R-DME-5654693); (R-DME-5654699); (R-DME-5654700); (R-DME-5654704); (R-DME-5654706); (R-DME-5654712); (R-DME-5654719); (R-DME-5673001); (R-DME-74749); (R-DME-74751); (R-DME-8853659); (R-DME-9013149); (R-DME-9607240)", "pathway_count": 34, "publication_count": 9, "publication_id_list": "10471707;10731132;12537569;12537572;12618399;1736363;18327897;1934068;7773779", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP. Functions in signaling pathways initiated by the sevenless and epidermal growth factor receptor tyrosine kinases; implies a role for the ras pathway in neuronal development., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWF4;Q8I067;Q8I0F7;Q8ITK2;Q95TI8;Q969D6;Q9VJV9", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane;GO:0035997 rhabdomere microvillus membrane", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0016199 axon midline choice point recognition;GO:0051607 defense response to virus;GO:0007265 Ras protein signal transduction;GO:0007173 epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P26675-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P28668-1", "uniprot_id": [ { "id": "SYEP_DROME", "url": "https://www.uniprot.org/uniprot/P28668", "type": "external" } ], "mass": 189412.0, "length": 1714, "protein_name": "Bifunctional glutamate/proline--tRNA ligase", "gene_name": "GluProRS", "organism": "Fruit fly", "refseq_name": "Glutamyl-prolyl-tRNA synthetase, isoform A", "refseq_ac": [ { "id": "NP_524471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524471", "type": "external" } ], "gene_names_uniprotkb": "GluProRS; Aats-glupro; CG5394", "gene_names_refseq": "AATS; AATs-GluPro; Aa-tRNA-syn-glupro; Aats-glupro; Aats-glu; CG5394; Dmel\\CG5394; EPRS; ERS; FBpp0083898; Glu-ProRS; GluPro-RS; GluProRS; GluRS; glutamyl-prolyl-tRNA synthetase; p200", "protein_names_uniprotkb": "Bifunctional glutamate/proline--tRNA ligase; Bifunctional aminoacyl-tRNA synthetase; Glutamyl-tRNA synthetase; ProRS; Prolyl-tRNA synthetase", "protein_names_refseq": "CG5394-PA; GluProRS-PA; Glutamyl-prolyl-tRNA synthetase, isoform A; Glutamyl-tRNA synthetase; aminoacyl-tRNA synthetase; bifunctional aminoacyl-tRNA synthetase; glutamyl-prolyl-tRA synthetase; transfer RNA-Glu-Pro aminoacyl synthetase", "tax_id": 7227, "disease": "hypomyelinating leukodystrophy 15 (Disease Ontology:DOID:0070398)", "pathway": " (dme:Dmel_CG5394); (R-DME-9856649)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;1756734;18327897;9063462", "class_list": "", "function": "Catalyzes the attachment of both L-glutamate and L-proline to their cognate tRNAs in a two-step reaction where the amino acid is first activated by ATP to form a covalent intermediate with AMP. Subsequently, the activated amino acid is transferred to the acceptor end of the cognate tRNA to form L-glutamyl-tRNA(Glu) and L-prolyl-tRNA(Pro)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IGR4;Q8IMX9;Q95TL3;Q9VCF5", "ec_number_list": [ { "id": "6.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.15", "type": "external" }, { "id": "6.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.17", "type": "external" }, { "id": "6.1.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.24", "type": "external" }, { "id": "6.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0004827 proline-tRNA ligase activity;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004818 glutamate-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0017101 aminoacyl-tRNA synthetase multienzyme complex", "go_biological_process": "GO:0006433 prolyl-tRNA aminoacylation;GO:0006424 glutamyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P28668-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P29327-1", "uniprot_id": [ { "id": "RS6_DROME", "url": "https://www.uniprot.org/uniprot/P29327", "type": "external" } ], "mass": 28407.0, "length": 248, "protein_name": "Small ribosomal subunit protein eS6", "gene_name": "RpS6", "organism": "Fruit fly", "refseq_name": "ribosomal protein S6, isoform B", "refseq_ac": [ { "id": "NP_511073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_511073", "type": "external" } ], "gene_names_uniprotkb": "RpS6; CG10944; hen; l(1)air8", "gene_names_refseq": "(Rp)S6; CG10944; DS6; Dmel\\CG10944; M(1)7BC; M(1)7C; RPS6; Rp S6; RpS6; Rps6; S6e; S6; air8; air[8]; anon-WO02059370.61; hen; l(1)air8; l(1)air[8]; l(1)hen; pp30; rpS6; rps6", "protein_names_uniprotkb": "Small ribosomal subunit protein eS6; 40S ribosomal protein S6", "protein_names_refseq": "CG10944-PB; RpS6-PB; S6 ribosomal protein; hemocytes enlarged; lethal(1)aberrant immune response[8]; lethal-(1)-haemocytes enlarged; lethal-aberrant-immune-response-8; minute (1) 7BC; ribosomal protein S6, isoform B; ribosomal protein S6", "tax_id": 7227, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); vascular dementia (Disease Ontology:DOID:8725)", "pathway": " (dme:Dmel_CG10944); (R-DME-156827); (R-DME-166208); (R-DME-1799339); (R-DME-6791226); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-9629569); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 15, "publication_count": 7, "publication_id_list": "10731132;12537572;1454811;18327897;23636399;8412647;8448211", "class_list": "", "function": "Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q94993;Q9W3N4", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P29327-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P29613-2", "uniprot_id": [ { "id": "TPIS_DROME", "url": "https://www.uniprot.org/uniprot/P29613", "type": "external" } ], "mass": 26626.0, "length": 247, "protein_name": "Triosephosphate isomerase", "gene_name": "Tpi", "organism": "Fruit fly", "refseq_name": "triose phosphate isomerase, isoform A", "refseq_ac": [ { "id": "NP_788764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788764", "type": "external" } ], "gene_names_uniprotkb": "Tpi; CG2171", "gene_names_refseq": "CG2171; Dmel\\CG2171; ND14; TPIS; TPI; Tpi; sgk; tpi; wstd", "protein_names_uniprotkb": "Triosephosphate isomerase; 5.3.1.1; TIM; Triose-phosphate isomerase", "protein_names_refseq": "CG2171-PA; Tpi-PA; neurodegeneration 14; sugarkill; triose phosphate isomerase, isoform A; triose phosphate isomerase; triosephosphate isomerase; wasted away", "tax_id": 7227, "disease": "triosephosphate isomerase deficiency (Disease Ontology:DOID:0050884); neurodegenerative disease (Disease Ontology:DOID:1289); cancer (Disease Ontology:DOID:162); carbohydrate metabolic disorder (Disease Ontology:DOID:2978); ocular hypertension (Disease Ontology:DOID:9282)", "pathway": " (dme:Dmel_CG2171); (R-DME-70171); (R-DME-70263)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537572;15952742;1720860;8500545;9615457", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76995;Q0KHY9;Q6NLI5;Q7JNU4;Q8IMJ1;Q9TY56", "ec_number_list": [ { "id": "5.3.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.1", "type": "external" } ], "go_molecular_function": "GO:0004807 triose-phosphate isomerase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030018 Z disc;GO:0031430 M band", "go_biological_process": "GO:0019682 glyceraldehyde-3-phosphate metabolic process;GO:0019563 glycerol catabolic process;GO:0050877 nervous system process;GO:0006094 gluconeogenesis;GO:0009612 response to mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P29613-2", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P29615-1", "uniprot_id": [ { "id": "LYSP_DROME", "url": "https://www.uniprot.org/uniprot/P29615", "type": "external" } ], "mass": 15648.0, "length": 141, "protein_name": "Lysozyme P", "gene_name": "LysP", "organism": "Fruit fly", "refseq_name": "lysozyme P", "refseq_ac": [ { "id": "NP_476828", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476828", "type": "external" } ], "gene_names_uniprotkb": "LysP; CG9116", "gene_names_refseq": "CG9116; Dmel\\CG9116; LysP; lysP", "protein_names_uniprotkb": "Lysozyme P; 1,4-beta-N-acetylmuramidase P; 3.2.1.17", "protein_names_refseq": "CG9116-PA; LysP-PA; lysozyme P; lysozyme", "tax_id": 7227, "disease": "gastroenteritis (Disease Ontology:DOID:2326)", "pathway": " (dme:Dmel_CG9116); (R-DME-6798695); (R-DME-6803157)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537572;1588905;8159165", "class_list": "glycogene;glycosylhydrolase", "function": "Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0JQ50;Q4V3V7;Q9W0J4", "ec_number_list": [ { "id": "3.5.2.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.17", "type": "external" }, { "id": "3.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.17", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "3.5.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.28", "type": "external" }, { "id": "3.2.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.14", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.5.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.26", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.3", "type": "external" }, { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "6.3.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21", "type": "external" }, { "id": "4.6.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.19", "type": "external" }, { "id": "3.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.51", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "3.4.17.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.13", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "1.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.2", "type": "external" } ], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0031640 killing of cells of another organism", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P29615-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32030-1", "uniprot_id": [ { "id": "SLP1_DROME", "url": "https://www.uniprot.org/uniprot/P32030", "type": "external" } ], "mass": 36223.0, "length": 322, "protein_name": "Fork head domain transcription factor slp1", "gene_name": "slp1", "organism": "Fruit fly", "refseq_name": "sloppy paired 1", "refseq_ac": [ { "id": "NP_476730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476730", "type": "external" } ], "gene_names_uniprotkb": "slp1; CG16738; FD6", "gene_names_refseq": "CG16738; Dmel\\CG16738; Dmslp1; FD6; FoxG; SLP1; SLP; Sloppy-paired; Slp-1; Slp1; Slp; l(2)05965; sko1; slp 1; slp-1; slp-2; slp1; slp", "protein_names_uniprotkb": "Fork head domain transcription factor slp1; Sloppy paired locus protein 1", "protein_names_refseq": "CG16738-PA; Sloppy-paired1; Sloppy-paired; sloppy paired 1; sloppy paired; sloppy-paired 1; sloppy-paired-1; slp1-PA", "tax_id": 7227, "disease": "primary ovarian insufficiency 3 (Disease Ontology:DOID:0080860); blepharophimosis, ptosis, and epicanthus inversus syndrome (Disease Ontology:DOID:14778); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); granulosa cell tumor (Disease Ontology:DOID:2999); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dme:Dmel_CG16738)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;1317319", "class_list": "", "function": "Transcription factor involved in segmentation. Required for the formation of the mandibular lobe. Different levels of slp activity seem to be required in different segments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q961V5;Q9VQV4", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P32030-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32031-1", "uniprot_id": [ { "id": "SLP2_DROME", "url": "https://www.uniprot.org/uniprot/P32031", "type": "external" } ], "mass": 49238.0, "length": 451, "protein_name": "Fork head domain transcription factor slp2", "gene_name": "slp2", "organism": "Fruit fly", "refseq_name": "sloppy paired 2", "refseq_ac": [ { "id": "NP_476834", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476834", "type": "external" } ], "gene_names_uniprotkb": "slp2; CG2939", "gene_names_refseq": "CG2939; Dmel\\CG2939; Dmslp2; FD7; FoxG; SLP; Sloppy-paired; Slp2; Slp; slp2; slp", "protein_names_uniprotkb": "Fork head domain transcription factor slp2; Sloppy paired locus protein 2", "protein_names_refseq": "CG2939-PA; Sloppy-paired; sloppy paired 2; sloppy paired; sloppy-paired 2; slp2-PA", "tax_id": 7227, "disease": "congenital variant of Rett syndrome (Disease Ontology:DOID:0070657); Rett syndrome (Disease Ontology:DOID:1206)", "pathway": " (dme:Dmel_CG2939); (R-DME-9617828)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;1317319", "class_list": "", "function": "Transcription factor involved in segmentation. May function primarily as a segment polarity gene. Different levels of slp activity seem to be required in different segments., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZ95;Q9VQV5", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007367 segment polarity determination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P32031-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32100-1", "uniprot_id": [ { "id": "RL7_DROME", "url": "https://www.uniprot.org/uniprot/P32100", "type": "external" } ], "mass": 29552.0, "length": 252, "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "RpL7", "organism": "Fruit fly", "refseq_name": "ribosomal protein L7, isoform B", "refseq_ac": [ { "id": "NP_001285794", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285794", "type": "external" } ], "gene_names_uniprotkb": "RpL7; BEST:GH04411; CG4897; Dmel\\CG4897; Dmel_CG4897; L30; L7; RPL7; Rp L7; rpL7; rpl7", "gene_names_refseq": "BEST:GH04411; CG4897; Dmel\\CG4897; L30; L7; RPL7; Rp L7; RpL7; rpL7; rpl7", "protein_names_uniprotkb": "Large ribosomal subunit protein uL30; 60S ribosomal protein L7", "protein_names_refseq": "CG4897-PB; RpL7-PB; ribosomal protein L7, isoform B; ribosomal protein L7", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4897); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357", "class_list": "", "function": "Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q541C8;Q9VL30", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0035073 pupariation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P32100-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P34739-1", "uniprot_id": [ { "id": "TTF2_DROME", "url": "https://www.uniprot.org/uniprot/P34739", "type": "external" } ], "mass": 118375.0, "length": 1061, "protein_name": "Transcription termination factor 2", "gene_name": "lds", "organism": "Fruit fly", "refseq_name": "lodestar", "refseq_ac": [ { "id": "NP_524850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524850", "type": "external" } ], "gene_names_uniprotkb": "lds; CG2684", "gene_names_refseq": "CG2684; DmF2; Dmel\\CG2684; Fs(3)Horka; Fs(3)Hor; Fs(3)Sz11; Horka; Lds; NTef2; lds; lod", "protein_names_uniprotkb": "Transcription termination factor 2; 3.6.4.-; Protein lodestar; RNA polymerase II termination factor; Transcription release factor 2", "protein_names_refseq": "CG2684-PA; early-3; early-5; early-B; factor 2; female sterile (3) horka; lds-PA; lodestar; negative transcription elongation factor 2; transcript A", "tax_id": 7227, "disease": "gastrointestinal system cancer (Disease Ontology:DOID:3119)", "pathway": " (dme:Dmel_CG2684)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;18327897;1916263;9748214", "class_list": "", "function": "DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VHY1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity;GO:0008094 ATP-dependent activity, acting on DNA", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0007283 spermatogenesis;GO:0007143 female meiotic nuclear division;GO:0006353 DNA-templated transcription termination;GO:0034454 microtubule anchoring at centrosome", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P34739-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35421-1", "uniprot_id": [ { "id": "PUR4_DROME", "url": "https://www.uniprot.org/uniprot/P35421", "type": "external" } ], "mass": 148085.0, "length": 1354, "protein_name": "Phosphoribosylformylglycinamidine synthase", "gene_name": "Pfas", "organism": "Fruit fly", "refseq_name": "phosphoribosylformylglycinamidine synthase, isoform A", "refseq_ac": [ { "id": "NP_477212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477212", "type": "external" } ], "gene_names_uniprotkb": "Pfas; CG9127; ade2", "gene_names_refseq": "153122_at; Ade2; CG9127; Dmel\\CG9127; Paics; Pfas; ade2; pfas; pym", "protein_names_uniprotkb": "Phosphoribosylformylglycinamidine synthase; 6.3.5.3; FGAM synthase; FGAMS; FGAR amidotransferase; FGAR-AT; Formylglycinamide ribonucleotide amidotransferase; Formylglycinamide ribotide amidotransferase; Protein adenosine-2", "protein_names_refseq": "CG9127-PA; Pfas-PA; adenosine 2; adenosine2; phosphoribosylformylglycinamidine synthase, isoform A", "tax_id": 7227, "disease": "colon adenocarcinoma (Disease Ontology:DOID:234); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG9127); (R-DME-73817)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537572;21441212;30249751;3086869;8270203", "class_list": "", "function": "Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway (PubMed:3086869). Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (PubMed:3086869). Because of its role in metabolisms, is involved in sleep regulation (PubMed:3086869)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V099;Q6NNY9;Q9VMI7", "ec_number_list": [ { "id": "6.3.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004642 phosphoribosylformylglycinamidine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009113 purine nucleobase biosynthetic process;GO:0006164 purine nucleotide biosynthetic process;GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P35421-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35600-1", "uniprot_id": [ { "id": "RFC1_DROME", "url": "https://www.uniprot.org/uniprot/P35600", "type": "external" } ], "mass": 108615.0, "length": 986, "protein_name": "Replication factor C subunit 1", "gene_name": "Gnf1", "organism": "Fruit fly", "refseq_name": "germ line transcription factor 1, isoform B", "refseq_ac": [ { "id": "NP_001014605", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014605", "type": "external" } ], "gene_names_uniprotkb": "Gnf1; CG1119", "gene_names_refseq": "CG1119; DmRFC1; Dmel\\CG1119; GTF-1; Gnf-1; Gnf1; Gtf1; ONF-CAACAA; RF-C 140; RFC140; RFC1; RFC; RfC140; RfC; dRF-Cp140; dRFC140; gnf1; gtf1; rfc1", "protein_names_uniprotkb": "Replication factor C subunit 1; Activator 1 140 kDa subunit; Activator 1 subunit 1; Germline transcription factor 1; Replication factor C large subunit", "protein_names_refseq": "CG1119-PB; Gnf1-PB; Replication-factor-C 140kD subunit; germ line transcription factor 1, isoform B; germline transcription factor; replication factor C 140kD subunit", "tax_id": 7227, "disease": "cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (Disease Ontology:DOID:0070148); congenital heart disease (Disease Ontology:DOID:1682); West Nile fever (Disease Ontology:DOID:2366)", "pathway": " (dme:Dmel_CG1119); (R-DME-110312); (R-DME-110314); (R-DME-110320); (R-DME-5651801); (R-DME-5655862); (R-DME-5656121); (R-DME-5656169); (R-DME-5696397); (R-DME-5696400); (R-DME-6782135); (R-DME-6782210); (R-DME-69091)", "pathway_count": 13, "publication_count": 5, "publication_id_list": "10731132;12537572;18327897;8999859;9705493", "class_list": "", "function": "The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds to the primer-template junction (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O02031;Q8MR76", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003689 DNA clamp loader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005663 DNA replication factor C complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0006260 DNA replication;GO:0048813 dendrite morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P35600-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35875-1", "uniprot_id": [ { "id": "PARP1_DROME", "url": "https://www.uniprot.org/uniprot/P35875", "type": "external" } ], "mass": 113792.0, "length": 994, "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "Parp1", "organism": "Fruit fly", "refseq_name": "Poly-(ADP-ribose) polymerase 1", "refseq_ac": [ { "id": "NP_001104452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104452", "type": "external" } ], "gene_names_uniprotkb": "Parp1; CG40411", "gene_names_refseq": "BEST:LD21673; CG17685; CG17696; CG17718; CG40411; D.PARP; Dm.pARTa; Dmel\\CG40411; LD21673.3prime; PARP-1; PARP1; PARPS-1; PARP; Parp1; Parp; dARTD1; dPARP1; dPARP; dParp1; dmparp; parp-1; parp", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase 1; 2.4.2.-; 2.4.2.30; ADPRT; NAD(+) ADP-ribosyltransferase; Poly[ADP-ribose] synthase; Protein ADP-ribosyltransferase Parp; dPARP1", "protein_names_refseq": "(Poly (ADP-ribose) polymeras; CG40411-PB; Parp1-PB; Poly(ADP ribose) polymerase 1; Poly(ADP)-Ribose polymerase; Poly(ADP-)Ribose polymerase; Poly(ADP-ribose) polymerase 1; Poly(ADP-ribose) polymerase; Poly-(ADP-ribose) polymerase 1; Poly-(ADP-ribose) polymerase; poly (ADP-ribose) polymerase; poly ADP ribose polymerase; poly ADP-ribose (ADPr) polymerase 1", "tax_id": 7227, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); kidney failure (Disease Ontology:DOID:1074); nephritis (Disease Ontology:DOID:10952); leiomyoma (Disease Ontology:DOID:127); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); transient cerebral ischemia (Disease Ontology:DOID:224); asthma (Disease Ontology:DOID:2841); middle cerebral artery infarction (Disease Ontology:DOID:3525); autoimmune disease (Disease Ontology:DOID:417); liver cirrhosis (Disease Ontology:DOID:5082); borna disease (Disease Ontology:DOID:5154); ureteral obstruction (Disease Ontology:DOID:5199); stomach carcinoma (Disease Ontology:DOID:5517); congestive heart failure (Disease Ontology:DOID:6000); arthritis (Disease Ontology:DOID:848); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); type 2 diabetes mellitus (Disease Ontology:DOID:9352); bacterial meningitis (Disease Ontology:DOID:9470)", "pathway": " (dme:Dmel_CG40411); (R-DME-5696394); (R-DME-5696395); (R-DME-5696400)", "pathway_count": 4, "publication_count": 19, "publication_id_list": "10731132;12183365;12537569;12537572;12543974;16219773;17827147;18614012;18922045;19229318;20371698;21444826;22178397;22242017;24508391;31028139;37268618;8475096;9565614", "class_list": "", "function": "Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:17827147). Mediates glutamate, aspartate or serine ADP-ribosylation of proteins; the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units (PubMed:37268618). Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins in absence of Hpf1 (By similarity). Following interaction with Hpf1, catalyzes serine ADP-ribosylation of target proteins; Hpf1 conferring serine specificity by completing the Parp active site (PubMed:37268618). ADP-ribosylates histone H1 upon activation by DNA and/or histone binding, inducing H1 to dissociate from nucleosomes (PubMed:31028139). ADP-ribosylates itself and other proteins to regulate their recruitment to Cajal bodies; required for Cajal body integrity (PubMed:19229318). Required for nucleolus integrity and the recruitment of other nucleolus components; this requires poly-ADP-ribosyltransferase activity (PubMed:22242017). Regulates the chromatin association of chromatin-remodeling complex ATPase chain Iswi (PubMed:18922045). Plays a fundamental role in organizing chromatin structure, particularly of heterochromatic regions and regions containing repetitive sequences (PubMed:12183365). Involved in activation of gene expression by inducing chromosome puffing; upon activation may poly-ADP-ribosylate chromatin associated proteins, disrupting their organization and leading to a local relaxation of chromatin structure (PubMed:12543974). Required for nucleosome loss and chromatin remodeling at the Hsp70 locus upon heat shock; involved in expression of heat shock response genes (PubMed:12543974, PubMed:18614012). Involved in expression of ecdysone response genes (PubMed:12543974). Involved in expression of NF-kappa-B-dependent immune response genes (PubMed:12543974). Involved in repression of transcription from heterochromatin, including of retrotransposons; autoregulates its own transcription by influencing the chromatin structure of its heterochromatic environment (PubMed:12183365, PubMed:20371698). Involved in ribosome biogenesis (PubMed:22242017)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Probably lacks enzymatic activity (Probable). Autoregulates Parp1 transcription by influencing the chromatin structure of its heterochromatic environment (PubMed:12183365)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8Y590;Q7PLT6;Q8MSB5;Q8MU87;Q9W5Q5;Q9W5S1", "ec_number_list": [ { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.4.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.30", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" } ], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0051287 NAD binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005694 chromosome;GO:0015030 Cajal body;GO:0000791 euchromatin", "go_biological_process": "GO:0007000 nucleolus organization;GO:1902570 protein localization to nucleolus;GO:1904867 protein localization to Cajal body;GO:0006974 DNA damage response;GO:0042254 ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P35875-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36241-1", "uniprot_id": [ { "id": "RL19_DROME", "url": "https://www.uniprot.org/uniprot/P36241", "type": "external" } ], "mass": 23998.0, "length": 203, "protein_name": "Large ribosomal subunit protein eL19", "gene_name": "RpL19", "organism": "Fruit fly", "refseq_name": "ribosomal protein L19, isoform A", "refseq_ac": [ { "id": "NP_476631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476631", "type": "external" } ], "gene_names_uniprotkb": "RpL19; CG2746; M(2)60E", "gene_names_refseq": "CG2746; Dmel\\CG2746; E(Dl)KP135; L19e; L19; M(2)60E; M(2)a; M(2)c; M60E; RPL19; Rp L19; RpL19; Rpl19; anon-EST:Posey33; l(2)SH1000; l(2)SH2 1000; l(2)k03704; rpL19; rpl19", "protein_names_uniprotkb": "Large ribosomal subunit protein eL19; 60S ribosomal protein L19", "protein_names_refseq": "CG2746-PA; Minute(2)60E; RpL19-PA; enhancer of delta KP135; lethal (2) SH1000; lethal (2) k03704; minute; ribosomal protein L19, isoform A; ribosomal protein L19", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2746); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23636399;8297785", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZV5;Q29QX6;Q9W0X4", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P36241-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36975-1", "uniprot_id": [ { "id": "SNP25_DROME", "url": "https://www.uniprot.org/uniprot/P36975", "type": "external" } ], "mass": 23685.0, "length": 212, "protein_name": "Synaptosomal-associated protein 25", "gene_name": "Snap25", "organism": "Fruit fly", "refseq_name": "Synaptosomal-associated protein 25kDa, isoform A", "refseq_ac": [ { "id": "NP_001036641", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036641", "type": "external" } ], "gene_names_uniprotkb": "Snap25; CG40452", "gene_names_refseq": "CG17676; CG17884; CG40452; Dmel\\CG40452; SNAP-25; SNAP25; Snap25; dSNAP-25; dSnap25; snap-25; snap25; snp25", "protein_names_uniprotkb": "Synaptosomal-associated protein 25; SNAP-25; Synaptosomal-associated 25 kDa protein", "protein_names_refseq": "CG40452-PA; Snap25-PA; Synaptosomal-associated protein 25kDa, isoform A; synapse protein 25; synaptosomal-associated protein 25", "tax_id": 7227, "disease": "developmental and epileptic encephalopathy 117 (Disease Ontology:DOID:0110683); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); Down syndrome (Disease Ontology:DOID:14250); epilepsy (Disease Ontology:DOID:1826); schizophrenia (Disease Ontology:DOID:5419); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG40452); (R-DME-181429); (R-DME-181430); (R-DME-199992); (R-DME-210500); (R-DME-212676); (R-DME-264642); (R-DME-449836); (R-DME-6798695); (R-DME-888590); (R-DME-8980692); (R-DME-9013149); (R-DME-9013406); (R-DME-9013423); (R-DME-9035034)", "pathway_count": 15, "publication_count": 4, "publication_id_list": "10731132;12537572;8226991;9272858", "class_list": "", "function": "May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F3YD56;Q5LJU6;Q7PLV2", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0043195 terminal bouton;GO:0031201 SNARE complex", "go_biological_process": "GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0016192 vesicle-mediated transport;GO:0007269 neurotransmitter secretion;GO:0006887 exocytosis;GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P36975-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38979-1", "uniprot_id": [ { "id": "RSSA_DROME", "url": "https://www.uniprot.org/uniprot/P38979", "type": "external" } ], "mass": 30228.0, "length": 270, "protein_name": "Small ribosomal subunit protein uS2", "gene_name": "sta", "organism": "Fruit fly", "refseq_name": "stubarista, isoform F", "refseq_ac": [ { "id": "NP_001284785", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284785", "type": "external" } ], "gene_names_uniprotkb": "sta; CG14792", "gene_names_refseq": "37LRP/p40; CG14792; Dmel\\CG14792; EG:80H7.6; Lam-r; P40; Rp 40; Rp40; RpSA; S2; STA; Sa; Sta; anon-EST:Liang-2.56; chrX:1339078..1339216; clone 2.56; k14; l(1)2Af; l(1)G0130; l(1)G0448; sta", "protein_names_uniprotkb": "Small ribosomal subunit protein uS2; 40S ribosomal protein SA; K14; Laminin receptor homolog; Protein stubarista", "protein_names_refseq": "CG14792-PF; Laminin-receptor; laminin receptor; ribosomal protein SA; sta-PF; stubarista, isoform F; stubarista", "tax_id": 7227, "disease": "arrhythmogenic right ventricular dysplasia 5 (Disease Ontology:DOID:0110074); sciatic neuropathy (Disease Ontology:DOID:11446); Diamond-Blackfan anemia (Disease Ontology:DOID:1339); irritable bowel syndrome (Disease Ontology:DOID:9778)", "pathway": " (dme:Dmel_CG14792); (R-DME-156827); (R-DME-1799339); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 12, "publication_count": 8, "publication_id_list": "10022917;10731132;10731137;12150910;12537569;12537572;23636399;7916731", "class_list": "", "function": "Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Required during oogenesis and imaginal development., [UniProtKB, PubMed, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q058X4;Q7KW10;Q9W583;X2JC80", "ec_number_list": [], "go_molecular_function": "GO:0043022 ribosome binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0005840 ribosome;GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38979-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39769-1", "uniprot_id": [ { "id": "PHP_DROME", "url": "https://www.uniprot.org/uniprot/P39769", "type": "external" } ], "mass": 167281.0, "length": 1589, "protein_name": "Polyhomeotic-proximal chromatin protein", "gene_name": "ph-p", "organism": "Fruit fly", "refseq_name": "polyhomeotic proximal, isoform A", "refseq_ac": [ { "id": "NP_476871", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476871", "type": "external" } ], "gene_names_uniprotkb": "ph-p; CG18412", "gene_names_refseq": "CG18412; CG18414; Dmel\\CG18412; EG:87B1.5; PH-p; PHP; PH; Ph-p; PhP; Ph; dPh; ph-P; ph-proximal; ph-p; ph[P]; ph[p]; phm; php; ph", "protein_names_uniprotkb": "Polyhomeotic-proximal chromatin protein", "protein_names_refseq": "CG18412-PA; Polyhomeotic-proximal; ph-p-PA; ph-proximal; polyhomeotic proximal, isoform A; polyhomeotic proximal; polyhomeotic proxima; polyhomeotic", "tax_id": 7227, "disease": "primary autosomal recessive microcephaly 11 (Disease Ontology:DOID:0070287); dilated cardiomyopathy (Disease Ontology:DOID:12930); cancer (Disease Ontology:DOID:162); tetralogy of Fallot (Disease Ontology:DOID:6419)", "pathway": " (dme:Dmel_CG18412)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;10731137;11493925;11583617;11992127;12537572;12771214;12834867;1346609;15905166;18327897;1937015;32510947;9343432", "class_list": "", "function": "Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility. Plays a role in regulating the expression of other pair-rule genes such as eve, ftz, and H., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "O46097;Q9W521;Q9W522", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0051087 protein-folding chaperone binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000785 chromatin;GO:0035102 PRC1 complex;GO:0005700 polytene chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0021954 central nervous system neuron development;GO:0009948 anterior/posterior axis specification;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P39769-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000100000000000.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39770-1", "uniprot_id": [ { "id": "SALM_DROME", "url": "https://www.uniprot.org/uniprot/P39770", "type": "external" } ], "mass": 150319.0, "length": 1365, "protein_name": "Homeotic protein spalt-major", "gene_name": "salm", "organism": "Fruit fly", "refseq_name": "spalt major, isoform A", "refseq_ac": [ { "id": "NP_723670", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_723670", "type": "external" } ], "gene_names_uniprotkb": "salm; 3602; B1164; CG6464; Dmel\\CG6464; Dmel_CG6464; SALM; SAL[M]; SAL; SPALT; SalM; Salm; Sal; Spalt; l(2)03602; salII; salM; sal; slam; spalt", "gene_names_refseq": "3602; B1164; CG6464; Dmel\\CG6464; SALM; SAL[M]; SAL; SPALT; SalM; Salm; Sal; Spalt; l(2)03602; salII; salM; salm; sal; slam; spalt", "protein_names_uniprotkb": "Homeotic protein spalt-major", "protein_names_refseq": "CG6464-PA; Spalt-M; sal major; salm-PA; spalt M; spalt major, isoform A; spalt major; spalt majr; spalt-major", "tax_id": 7227, "disease": "Townes-Brocks syndrome (Disease Ontology:DOID:0050887); Holt-Oram syndrome (Disease Ontology:DOID:0060468); Duane-radial ray syndrome (Disease Ontology:DOID:0060747); IVIC syndrome (Disease Ontology:DOID:0111381); otitis media (Disease Ontology:DOID:10754); Duane retraction syndrome (Disease Ontology:DOID:12557); ventricular septal defect (Disease Ontology:DOID:1657); endodermal sinus tumor (Disease Ontology:DOID:1911); ovarian germ cell cancer (Disease Ontology:DOID:2156); carcinoma (Disease Ontology:DOID:305); hepatoblastoma (Disease Ontology:DOID:687)", "pathway": " (dme:Dmel_CG6464); (R-DME-8943724)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;7905822", "class_list": "", "function": "Required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo. Probably function as a transcriptional regulator. Could repress the transcription of the tsh gene., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8MSC6;Q9VKH2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007525 somatic muscle development;GO:0021782 glial cell development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P39770-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40139-1", "uniprot_id": [ { "id": "NG2_DROME", "url": "https://www.uniprot.org/uniprot/P40139", "type": "external" } ], "mass": 11986.0, "length": 112, "protein_name": "Protein new-glue 2", "gene_name": "ng2", "organism": "Fruit fly", "refseq_name": "new glue 2", "refseq_ac": [ { "id": "NP_476941", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476941", "type": "external" } ], "gene_names_uniprotkb": "ng2; CG14266", "gene_names_refseq": "BcDNA:RE05239; CG14266; Dmel\\CG14266; EG:96G10.4; NG2; ng-2; ng2; ng", "protein_names_uniprotkb": "Protein new-glue 2; NG-2", "protein_names_refseq": "CG14266-PA; new glue 2; ng2-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14266)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;10731137;12537569;12537572;8510164", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76916;Q9V3M0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40139-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40140-1", "uniprot_id": [ { "id": "NG3_DROME", "url": "https://www.uniprot.org/uniprot/P40140", "type": "external" } ], "mass": 15952.0, "length": 146, "protein_name": "Protein new-glue 3", "gene_name": "ng3", "organism": "Fruit fly", "refseq_name": "new glue 3", "refseq_ac": [ { "id": "NP_525060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_525060", "type": "external" } ], "gene_names_uniprotkb": "ng3; CG10788", "gene_names_refseq": "BcDNA:LP03924; CG10788; Dmel\\CG10788; EG:96G10.3; ng-3; ng3; ng", "protein_names_uniprotkb": "Protein new-glue 3; NG-3", "protein_names_refseq": "CG10788-PB; new glue 3; ng3-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10788)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;10731137;12537569;12537572;8510164", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76915;Q8MS91", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40140-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40301-1", "uniprot_id": [ { "id": "PSA2_DROME", "url": "https://www.uniprot.org/uniprot/P40301", "type": "external" } ], "mass": 25907.0, "length": 234, "protein_name": "Proteasome subunit alpha type-2", "gene_name": "Prosalpha2", "organism": "Fruit fly", "refseq_name": "proteasome alpha2 subunit", "refseq_ac": [ { "id": "NP_524328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524328", "type": "external" } ], "gene_names_uniprotkb": "Prosalpha2; CG5266; PROS-25; Pros25", "gene_names_refseq": "153303_at; 20S-(a); 20S-alpha; Alpha-2; CG5266; Dmel\\CG5266; PRC3; PROS Dm25; PROS-Dm25g; PSA2_DROME; Pros alpha2; Pros25; Prosalpha2; Prot. 25 Kda; Su(DTS)-1; Su(DTS); alpha-2; alpha2_dm; alpha2; dalpha2; pros25; prosalpha2", "protein_names_uniprotkb": "Proteasome subunit alpha type-2; PROS-Dm25; Proteasome 25 kDa subunit", "protein_names_refseq": "20s proteasome; CG5266-PA; Pros25; Prosalpha2-PA; Su(DTS)-1; alpha-subunit of 20S proteasome; alpha2 subunit; alpha2; proteasome 25kD subunit; proteasome alpha2 subunit; proteasome subunit alpha-type 2; proteosome", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5266); (R-DME-1169091); (R-DME-1234176); (R-DME-1236974); (R-DME-1236978); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209406); (R-DME-209461); (R-DME-216167); (R-DME-2467813); (R-DME-2871837); (R-DME-350562); (R-DME-382556); (R-DME-432395); (R-DME-432524); (R-DME-432626); (R-DME-450408); (R-DME-4608870); (R-DME-4641257); (R-DME-4641258); (R-DME-5358346); (R-DME-538864); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5632684); (R-DME-5658442); (R-DME-5676590); (R-DME-5689603); (R-DME-5689880); (R-DME-6798695); (R-DME-68867); (R-DME-68949); (R-DME-69017); (R-DME-69601); (R-DME-75815); (R-DME-8854050); (R-DME-8939236); (R-DME-8939902); (R-DME-8941858); (R-DME-8948751); (R-DME-8951664); (R-DME-9020702); (R-DME-9755511); (R-DME-9762114); (R-DME-983168); (R-DME-9907900); (R-DME-9912633); (R-DME-9929491); (R-DME-9932298); (R-DME-9954709)", "pathway_count": 59, "publication_count": 37, "publication_id_list": "10102270;10417378;10458606;10481010;10731132;11585911;12231619;12432393;12442174;12537569;12537572;12973300;15178801;15258584;15331761;16139204;16299518;16326393;16386907;16543224;16603629;16651542;16740475;16794082;17102630;17925225;18519643;18593878;19185492;22187461;7705656;8357840;8948598;9025065;9215627;9553105;9990853", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VG71", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex;GO:0019773 proteasome core complex, alpha-subunit complex;GO:0005839 proteasome core complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 3.8, "record_id": "P40301-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40657-1", "uniprot_id": [ { "id": "SOX15_DROME", "url": "https://www.uniprot.org/uniprot/P40657", "type": "external" } ], "mass": 84872.0, "length": 784, "protein_name": "Putative transcription factor SOX-15", "gene_name": "Sox15", "organism": "Fruit fly", "refseq_name": "Sox box protein 15", "refseq_ac": [ { "id": "NP_523739", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523739", "type": "external" } ], "gene_names_uniprotkb": "Sox15; CG8404; SOX50E", "gene_names_refseq": "CG13945; CG8404; DSox-15; Dmel\\CG8404; Dsox-15; SOX15; SOX50E; SOXF; Sox F; Sox15; Sox50E; SoxE; SoxF; sox15", "protein_names_uniprotkb": "Putative transcription factor SOX-15; Sox50E", "protein_names_refseq": "CG8404-PA; Sox box protein 15; Sox15-PA", "tax_id": 7227, "disease": "hypotrichosis-lymphedema-telangiectasia-renal defect syndrome (Disease Ontology:DOID:0111360); hypotrichosis-lymphedema-telangiectasia syndrome (Disease Ontology:DOID:0111361); intracranial aneurysm (Disease Ontology:DOID:10941); biliary atresia (Disease Ontology:DOID:13608); patent ductus arteriosus (Disease Ontology:DOID:13832); primary pulmonary hypertension (Disease Ontology:DOID:14557); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); cholangiocarcinoma (Disease Ontology:DOID:4947); pulmonary hypertension (Disease Ontology:DOID:6432); vesicoureteral reflux (Disease Ontology:DOID:9620)", "pathway": " (dme:Dmel_CG8404); (R-DME-3769402)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;1614875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1LZ22;Q4V734;Q9U1J5;Q9V6Y8", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P40657-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40797-1", "uniprot_id": [ { "id": "PNUT_DROME", "url": "https://www.uniprot.org/uniprot/P40797", "type": "external" } ], "mass": 60143.0, "length": 539, "protein_name": "Protein peanut", "gene_name": "pnut", "organism": "Fruit fly", "refseq_name": "peanut, isoform A", "refseq_ac": [ { "id": "NP_477064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477064", "type": "external" } ], "gene_names_uniprotkb": "pnut; CG8705", "gene_names_refseq": "CG8705; Dmel\\CG8705; E(sina)44C; E(sina)8; PNUT; Peanut; Pnut; anon-EST:Liang-2.18; clone 2.18; dSEPT7; l(2)02502; pnt; pnut", "protein_names_uniprotkb": "Protein peanut", "protein_names_refseq": "CG8705-PA; enhancer of seven in absentia 8; peanut, isoform A; peanut; pnut-PA; septin 3; septin 7; septin[Pnut]; septin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8705)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;15818553;17372656;17456438;18327897;29079679;8181057;8590810", "class_list": "", "function": "Involved in cytokinesis and possibly cellularization (PubMed:8181057). Also acts as an enhancer of the sina gene, thus having a role in photoreceptor development (PubMed:8181057). May be involved in p53-dependent apoptosis (PubMed:17456438)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E9F5;Q9V385", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003779 actin binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005940 septin ring;GO:0005886 plasma membrane;GO:0015630 microtubule cytoskeleton;GO:0016324 apical plasma membrane;GO:0045171 intercellular bridge", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0006915 apoptotic process;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization;GO:0042461 photoreceptor cell development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40797-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40809-1", "uniprot_id": [ { "id": "RG84C_DROME", "url": "https://www.uniprot.org/uniprot/P40809", "type": "external" } ], "mass": 44217.0, "length": 384, "protein_name": "GTPase-activating protein RacGAP84C", "gene_name": "RacGAP84C", "organism": "Fruit fly", "refseq_name": "Rac GTPase activating protein at 84C, isoform B", "refseq_ac": [ { "id": "NP_476703", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476703", "type": "external" } ], "gene_names_uniprotkb": "RacGAP84C; CG2595; rnRacGAP", "gene_names_refseq": "CG2595; Dmel\\CG2595; GAP84C; P1.7; RacGAP(84C); RacGAP84C; RhoGAP-84C8; racGAP; rnGAP; rnRac-GAP; rnRacGAP; rnRacGap; rnprot1.7; rnprot; rnracGAP; rnracGap", "protein_names_uniprotkb": "GTPase-activating protein RacGAP84C; Protein rotund RacGAP", "protein_names_refseq": "CG2595-PB; Rac GTPase activating protein at 84C, isoform B; RacGAP84C-PB; RnRacGAP; RotundRACGAP; rotund RacGAP", "tax_id": 7227, "disease": "congenital dyserythropoietic anemia type IIIb (Disease Ontology:DOID:0051001)", "pathway": " (dme:Dmel_CG2595)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;1406685;8654933", "class_list": "", "function": "Involved in the morphogenesis of the adult appendages. GTPase-activating protein for p21-Rac. Promotes the exchange of Rac-bound GDP by GTP., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VI91", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0051233 spindle midzone;GO:0032154 cleavage furrow;GO:0030496 midbody;GO:0097149 centralspindlin complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0007266 Rho protein signal transduction;GO:0000281 mitotic cytokinesis;GO:0051256 mitotic spindle midzone assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40809-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41042-1", "uniprot_id": [ { "id": "RS4_DROME", "url": "https://www.uniprot.org/uniprot/P41042", "type": "external" } ], "mass": 29134.0, "length": 261, "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RpS4", "organism": "Fruit fly", "refseq_name": "ribosomal protein S4, isoform C", "refseq_ac": [ { "id": "NP_001287055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287055", "type": "external" } ], "gene_names_uniprotkb": "RpS4; CG11276; Dmel\\CG11276; Dmel_CG11276; RP4; RPS4; Rp S4; S4e; SX4; anon-EST:Posey270; rpS4", "gene_names_refseq": "CG11276; Dmel\\CG11276; RPS4; Rp S4; RpS4; S4e; SX4; anon-EST:Posey270; rpS4", "protein_names_uniprotkb": "Small ribosomal subunit protein eS4; 40S ribosomal protein S4", "protein_names_refseq": "CG11276-PC; RpS4-PC; ribosomal protein S4, isoform C; ribosomal protein S4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11276); (R-DME-156827); (R-DME-1799339); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 12, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;23636399;25589440;26109356;26109357;8224871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1X0;Q9VU44", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022627 cytosolic small ribosomal subunit;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P41042-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41093-1", "uniprot_id": [ { "id": "RL18A_DROME", "url": "https://www.uniprot.org/uniprot/P41093", "type": "external" } ], "mass": 21030.0, "length": 177, "protein_name": "Large ribosomal subunit protein eL20", "gene_name": "RpL18A", "organism": "Fruit fly", "refseq_name": "ribosomal protein L18A", "refseq_ac": [ { "id": "NP_523774", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523774", "type": "external" } ], "gene_names_uniprotkb": "RpL18A; CG6510", "gene_names_refseq": "CG6510; Dmel\\CG6510; L18A; L18a; L18; L20e; RPL18a; RpL18A; RpL18a; Rpl18A; anon-EST:Posey75", "protein_names_uniprotkb": "Large ribosomal subunit protein eL20; 60S ribosomal protein L18a", "protein_names_refseq": "CG6510-PA; RpL18A-PA; ribosomal protein L18A", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG6510); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23636399;8018724", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V840", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P41093-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41900-1", "uniprot_id": [ { "id": "T2FB_DROME", "url": "https://www.uniprot.org/uniprot/P41900", "type": "external" } ], "mass": 32107.0, "length": 277, "protein_name": "General transcription factor IIF subunit 2", "gene_name": "TfIIFbeta", "organism": "Fruit fly", "refseq_name": "transcription factor TFIIFbeta", "refseq_ac": [ { "id": "NP_524305", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524305", "type": "external" } ], "gene_names_uniprotkb": "TfIIFbeta; CG6538; TFIIF30", "gene_names_refseq": "CG6538; Dmel\\CG6538; F[[S]]; RAP30; T2FB_DROME; TFIIFbeta; TFIIF; TfIIFbeta; TfIIF; dTFIIF30; l(3)j3C1", "protein_names_uniprotkb": "General transcription factor IIF subunit 2; TFIIF-beta; Transcription initiation factor IIF subunit beta", "protein_names_refseq": "CG6538-PA; TFIIF small subunit; TfIIFbeta-PA; factor 5; transcription factor TFIIFbeta", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6538); (R-DME-112382); (R-DME-113418); (R-DME-674695); (R-DME-6796648); (R-DME-6807505); (R-DME-72086); (R-DME-72163); (R-DME-72165); (R-DME-72203); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075); (R-DME-9018519); (R-DME-9770562)", "pathway_count": 18, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;7596813;7890767", "class_list": "", "function": "TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VGX4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0001096 TFIIF-class transcription factor complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005674 transcription factor TFIIF complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P41900-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42278-1", "uniprot_id": [ { "id": "TRYT_DROME", "url": "https://www.uniprot.org/uniprot/P42278", "type": "external" } ], "mass": 28378.0, "length": 262, "protein_name": "Trypsin theta", "gene_name": "thetaTry", "organism": "Fruit fly", "refseq_name": "thetaTrypsin", "refseq_ac": [ { "id": "NP_523693", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523693", "type": "external" } ], "gene_names_uniprotkb": "thetaTry; CG12385", "gene_names_refseq": "CG12385; DmThetaTry; Dmel\\CG12385; SP139; Try; thetaTry", "protein_names_uniprotkb": "Trypsin theta; 3.4.21.4", "protein_names_refseq": "CG12385-PA; thetaTry-PA; thetaTrypsin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12385)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10486967;10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZQ7;Q9V5Y0", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0017171 serine hydrolase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P42278-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42286-1", "uniprot_id": [ { "id": "THR_DROME", "url": "https://www.uniprot.org/uniprot/P42286", "type": "external" } ], "mass": 157553.0, "length": 1379, "protein_name": "Protein three rows", "gene_name": "thr", "organism": "Fruit fly", "refseq_name": "three rows, isoform C", "refseq_ac": [ { "id": "NP_001286552", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286552", "type": "external" } ], "gene_names_uniprotkb": "thr; CG5785", "gene_names_refseq": "CG5785; Dmel\\CG5785; THR; Thr; ana; anch; frag1; thr", "protein_names_uniprotkb": "Protein three rows", "protein_names_refseq": "CG5785-PC; anarchist; fragmented gonads 1; separase; thr-PC; three rows, isoform C; three rows", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5785)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;11581162;12231632;12537569;12537572;8270646;8305737;9927461", "class_list": "", "function": "Required specifically for chromosome disjunction during all mitoses; maternally provided protein is sufficient until mitosis 14 then zygotic protein is required. Involved in formation and/or maintenance of epithelial structures: bud extension during Malpighian tubule development, and foregut and hindgut morphogenesis., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4LFY0;Q8MQL8;Q94525;Q9V894", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007442 hindgut morphogenesis;GO:0051301 cell division;GO:0051306 mitotic sister chromatid separation;GO:0000070 mitotic sister chromatid segregation;GO:0002009 morphogenesis of an epithelium", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P42286-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42570-1", "uniprot_id": [ { "id": "PLU_DROME", "url": "https://www.uniprot.org/uniprot/P42570", "type": "external" } ], "mass": 19319.0, "length": 174, "protein_name": "DNA replication inhibitor plutonium", "gene_name": "plu", "organism": "Fruit fly", "refseq_name": "plutonium", "refseq_ac": [ { "id": "NP_476683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476683", "type": "external" } ], "gene_names_uniprotkb": "plu; CG9183", "gene_names_refseq": "CG9183; Dmel\\CG9183; PLU; Plu; plu", "protein_names_uniprotkb": "DNA replication inhibitor plutonium", "protein_names_refseq": "CG9183-PA; plu-PA; plutonium", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9183)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;18327897;8313891", "class_list": "", "function": "Inhibits DNA replication early in developments. May bind and block the action of a replication or initiation factor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V910", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:1902554 serine/threonine protein kinase complex;GO:1902911 protein kinase complex", "go_biological_process": "GO:0007338 single fertilization;GO:0006260 DNA replication;GO:0007346 regulation of mitotic cell cycle;GO:0008156 negative regulation of DNA replication;GO:0007343 egg activation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P42570-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43332-1", "uniprot_id": [ { "id": "SNRPA_DROME", "url": "https://www.uniprot.org/uniprot/P43332", "type": "external" } ], "mass": 24547.0, "length": 216, "protein_name": "U1 small nuclear ribonucleoprotein A", "gene_name": "snf", "organism": "Fruit fly", "refseq_name": "sans fille", "refseq_ac": [ { "id": "NP_511045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_511045", "type": "external" } ], "gene_names_uniprotkb": "snf; CG4528; D25; fs(1)1621; liz", "gene_names_refseq": "CG4528; D25; Dmel\\CG4528; SNF/D25; SNF; Snf; U1-A; U1A; U2 snRNP B'' protein; U2 snRNP; U2B; dSNF; fs(1)1621; fs(1)A16121; fs(1)A1621; liz; snRNP B''; snRNP-U1-A; snf1621; snf", "protein_names_uniprotkb": "U1 small nuclear ribonucleoprotein A; Sex determination protein snf; U1 snRNP A; U1-A; U1A", "protein_names_refseq": "CG4528-PA; Sans-fille; sans fille; simply not fertile; snf-PA; splicing necessary factor", "tax_id": 7227, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); disease of cellular proliferation (Disease Ontology:DOID:14566); germ cell cancer (Disease Ontology:DOID:2994); connective tissue disease (Disease Ontology:DOID:65)", "pathway": " (dme:Dmel_CG4528); (R-DME-72163); (R-DME-9770562); (R-DME-9943411)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;1386424;18621711;7926776", "class_list": "", "function": "Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP (By similarity). Plays a role in regulating sex-lethal splicing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W4D7", "ec_number_list": [], "go_molecular_function": "GO:0030620 U2 snRNA binding;GO:0097158 pre-mRNA intronic pyrimidine-rich binding;GO:0008266 poly(U) RNA binding;GO:0030619 U1 snRNA binding;GO:0035614 snRNA stem-loop binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0071013 catalytic step 2 spliceosome;GO:0032991 protein-containing complex;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0008380 RNA splicing;GO:0000398 mRNA splicing, via spliceosome;GO:0048477 oogenesis;GO:0000381 regulation of alternative mRNA splicing, via spliceosome;GO:0007539 primary sex determination, soma", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43332-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P45843-1", "uniprot_id": [ { "id": "SCRT_DROME", "url": "https://www.uniprot.org/uniprot/P45843", "type": "external" } ], "mass": 74458.0, "length": 666, "protein_name": "Protein scarlet", "gene_name": "st", "organism": "Fruit fly", "refseq_name": "scarlet", "refseq_ac": [ { "id": "NP_524108", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524108", "type": "external" } ], "gene_names_uniprotkb": "st; CG4314", "gene_names_refseq": "CG4314; DmScarlet; Dmel\\CG4314; ST; st", "protein_names_uniprotkb": "Protein scarlet; 7.6.2.-; ATP-binding cassette transporter sub-family G member scarlet; Broad substrate specificity ATP-binding cassette transporter scarlet", "protein_names_refseq": "CG4314-PA; scarlet; st-PA", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG4314)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10407069;10731132;11294610;12537572;18931318;2503416;29367274;33820991;812484;8544833", "class_list": "", "function": "ATP-dependent transporter of the ATP-binding cassette (ABC) family which transports various molecules including bioamines, neurotransmitters and metabolic intermediates (PubMed:18931318, PubMed:33820991, PubMed:812484). In the eye and probably in association with w/white, required for the transport of the eye brown pigment precursors, kynurenine and probably tryptophan, into pigment cell granules (PubMed:10407069, PubMed:812484). In Malpighian tubules and pupal eyes, involved in kynurenine transport (PubMed:812484). Probably in association with w/white, plays a role in zinc storage granule biogenesis in Malpighian tubule principal epithelial cells (PubMed:29367274)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q6NP00;Q6NR69;Q9VV67", "ec_number_list": [ { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "7.6.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0022857 transmembrane transporter activity;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0005275 amine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0098793 presynapse;GO:0090741 pigment granule membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015842 aminergic neurotransmitter loading into synaptic vesicle;GO:0006856 eye pigment precursor transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P45843-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P45975-1", "uniprot_id": [ { "id": "SUV39_DROME", "url": "https://www.uniprot.org/uniprot/P45975", "type": "external" } ], "mass": 71831.0, "length": 635, "protein_name": "Histone-lysine N-methyltransferase Su(var)3-9", "gene_name": "Su(var)3-9", "organism": "Fruit fly", "refseq_name": "suppressor of variegation 3-9", "refseq_ac": [ { "id": "NP_524357", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524357", "type": "external" } ], "gene_names_uniprotkb": "Su(var)3-9; CG6476; KMT1", "gene_names_refseq": "CG43664; CG6476; Dmel\\CG43664; E(var)3-2; SU(VAR)3-9; SUV39H1; SUV39; Su(VAR)3-9; Su(Var)3-9; Su(var) 3-9; Su(var)3-902; Su(var)3-9; Su(var)306; Su(var)310; Su(var)328; Su(var); Su-var(3)902; Su-var(3)9; SuVar3-9; Suv 3-9; Suvar(3)9; Suvar3-9; Suvar39; caa56376 Suvar39 Dm; dSU(VAR)3-9; dSu(var)3-9; ptn; su(var)3-9; suv39", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase Su(var)3-9; 2.1.1.355; H3-K9-HMTase; Histone H3-K9 methyltransferase; Lysine N-methyltransferase 1; Protein suppressor of variegation 3-9", "protein_names_refseq": "CG43664-PA; Su(var)3-9-PA; enhancer of variegation 3-2; histone methyltransferase; pitkin; suppressor of variegation 3-9; suppressor of variegation 306; suppressor of variegation 310; suppressor of variegation 328", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43664); (R-DME-427359)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;11063691;11571273;11867540;12537572;14630943;26389589;7915232", "class_list": "", "function": "Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric regions. Involved in heterochromatic gene silencing including the modification of position-effect-variegation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFA6", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042054 histone methyltransferase activity;GO:0046974 histone H3K9 methyltransferase activity;GO:0140942 histone H3K9 dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000792 heterochromatin;GO:0005721 pericentric heterochromatin;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031508 pericentric heterochromatin formation;GO:0031509 subtelomeric heterochromatin formation;GO:2001229 negative regulation of response to gamma radiation;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P45975-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47938-1", "uniprot_id": [ { "id": "THIO1_DROME", "url": "https://www.uniprot.org/uniprot/P47938", "type": "external" } ], "mass": 12384.0, "length": 107, "protein_name": "Thioredoxin-1", "gene_name": "dhd", "organism": "Fruit fly", "refseq_name": "deadhead, isoform B", "refseq_ac": [ { "id": "NP_001284882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284882", "type": "external" } ], "gene_names_uniprotkb": "dhd; 4193; CG4193; DHD; Dhd; DmTrx-1; Dmdhd; Dmel\\CG4193; Dmel_CG4193; Dmeldhd; Trx-1; Trx1", "gene_names_refseq": "4193; CG4193; DHD; Dhd; DmTrx-1; Dmdhd; Dmel\\CG4193; Dmeldhd; Trx-1; Trx1; dhd", "protein_names_uniprotkb": "Thioredoxin-1; DmTrx-1; Protein deadhead", "protein_names_refseq": "CG4193-PB; deadhead, isoform B; deadhead; dhd-PB; thioredoxin-like", "tax_id": 7227, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); glaucoma (Disease Ontology:DOID:1686); myocardial infarction (Disease Ontology:DOID:5844); myocarditis (Disease Ontology:DOID:820); intermediate coronary syndrome (Disease Ontology:DOID:8805); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (dme:Dmel_CG4193)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;11877442;12537568;12537569;12537572;12537573;12537574;14579129;15952742;16110336;17569856;17569867;25589440;26109356;26109357;7516301;9106167", "class_list": "", "function": "Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MSC0;Q9W4D5", "ec_number_list": [], "go_molecular_function": "GO:0015038 glutathione disulfide oxidoreductase activity;GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007143 female meiotic nuclear division;GO:0060322 head development;GO:0035041 sperm DNA decondensation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P47938-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48159-1", "uniprot_id": [ { "id": "RL23_DROME", "url": "https://www.uniprot.org/uniprot/P48159", "type": "external" } ], "mass": 14937.0, "length": 140, "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "RpL23", "organism": "Fruit fly", "refseq_name": "ribosomal protein L23", "refseq_ac": [ { "id": "NP_523813", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523813", "type": "external" } ], "gene_names_uniprotkb": "RpL23; CG3661; RpL17A", "gene_names_refseq": "CG3661; Dmel\\CG3661; L14; L17A; L17; L23; RL17; RPL17A; RpL17A; RpL23; Rpl17A; Rpl23; TA01212p; rpl23", "protein_names_uniprotkb": "Large ribosomal subunit protein uL14; 60S ribosomal protein L23; L17A", "protein_names_refseq": "CG3661-PA; RpL23-PA; ribosomal protein L17A; ribosomal protein L23", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3661); (R-DME-156827); (R-DME-1799339); (R-DME-72689); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954709); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "10731132;12537572;1511900;23636399", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B7FNL0;Q9W1Y7", "ec_number_list": [], "go_molecular_function": "GO:0017022 myosin binding;GO:0003735 structural constituent of ribosome;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P48159-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48591-1", "uniprot_id": [ { "id": "RIR1_DROME", "url": "https://www.uniprot.org/uniprot/P48591", "type": "external" } ], "mass": 91978.0, "length": 812, "protein_name": "Ribonucleoside-diphosphate reductase large subunit", "gene_name": "RnrL", "organism": "Fruit fly", "refseq_name": "ribonucleoside diphosphate reductase large subunit", "refseq_ac": [ { "id": "NP_477027", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477027", "type": "external" } ], "gene_names_uniprotkb": "RnrL; CG5371", "gene_names_refseq": "CG5371; DmRNR1; Dmel\\CG5371; R1; RNR1; RNRL; RnrL; RnrM1; RntL; l(2)k06709; rnrL", "protein_names_uniprotkb": "Ribonucleoside-diphosphate reductase large subunit; 1.17.4.1; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit", "protein_names_refseq": "CG5371-PA; RnrL-PA; ribonucleoside diphosphate reductase M1 subunit; ribonucleoside diphosphate reductase large subunit; ribonucleoside-diphosphate reductase large subunit", "tax_id": 7227, "disease": "chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dme:Dmel_CG5371); (R-DME-499943)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;10731138;12537572;18327897;8050359", "class_list": "", "function": "Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9UB08;Q9VKZ3", "ec_number_list": [ { "id": "1.17.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.4.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor", "go_cellular_component": "GO:0005971 ribonucleoside-diphosphate reductase complex", "go_biological_process": "GO:0042246 tissue regeneration;GO:0009263 deoxyribonucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P48591-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48607-1", "uniprot_id": [ { "id": "SPZ_DROME", "url": "https://www.uniprot.org/uniprot/P48607", "type": "external" } ], "mass": 37447.0, "length": 326, "protein_name": "Protein spaetzle", "gene_name": "spz", "organism": "Fruit fly", "refseq_name": "spatzle, isoform A", "refseq_ac": [ { "id": "NP_524526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524526", "type": "external" } ], "gene_names_uniprotkb": "spz; CG6134; CT19282; Dmel\\CG6134; Dmel_CG6134; SPZ; Spatzle; Spz-1; Spz1; Spz; mel(3)7", "gene_names_refseq": "CG6134; CT19282; Dmel\\CG6134; SPZ; Spatzle; Spz-1; Spz1; Spz; mel(3)7; spz", "protein_names_uniprotkb": "Protein spaetzle; Protein spatzle", "protein_names_refseq": "CG6134-PA; protein spaetzle precursor; spaetzle; spatzle, isoform A; spatzle; spazle; spaztle; spz-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6134); (R-DME-209442); (R-DME-214842); (R-DME-214844); (R-DME-214862); (R-DME-214863); (R-DME-214869); (R-DME-214874)", "pathway_count": 8, "publication_count": 43, "publication_id_list": "10072384;10660298;10731132;11212919;11296245;11350927;11493599;11532919;11934858;12493753;12537568;12537569;12537572;12537573;12537574;12872120;14667416;14685264;15197269;15795223;16110336;16399077;16782008;16996061;17324925;17569856;17569867;18347020;18790733;20605458;24282309;24733933;25589440;26109356;26109357;8026333;8124709;8808632;8948598;9367441;9405646;9533958;9806920", "class_list": "", "function": "The activated form, spaetzle C-106, acts as a ligand for the Toll receptor (PubMed:12872120). Binding to Toll activates the Toll signaling pathway and induces expression of the antifungal peptide drosomycin (PubMed:8808632). Component of the extracellular signaling pathway that establishes dorsal-ventral polarity in the embryo (PubMed:11212919, PubMed:8124709)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q95SU5;Q9VB84", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0048018 receptor ligand activity;GO:0005121 Toll binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0042542 response to hydrogen peroxide", "synthesized_glycan_count": 0, "hit_score": 4.4, "record_id": "P48607-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q59DX8-1", "uniprot_id": [ { "id": "NAA80_DROME", "url": "https://www.uniprot.org/uniprot/Q59DX8", "type": "external" } ], "mass": 20373.0, "length": 178, "protein_name": "N-alpha-acetyltransferase 80", "gene_name": "Naa80", "organism": "Fruit fly", "refseq_name": "N(alpha)-acetyltransferase 80, isoform B", "refseq_ac": [ { "id": "NP_001014612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014612", "type": "external" } ], "gene_names_uniprotkb": "Naa80; CG8481", "gene_names_refseq": "CG8481; DmNAA80; Dmel\\CG8481; NAA80; Naa80", "protein_names_uniprotkb": "N-alpha-acetyltransferase 80; 2.3.1.-; DmNAA80", "protein_names_refseq": "CG8481-PB; N(alpha)-acetyltransferase 80, isoform B; Naa80-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8481)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;29581307", "class_list": "", "function": "N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine (PubMed:29581307). Preferentially acts on proteins starting with Asp-Asp-Asp and Glu-Glu-Glu sequences (PubMed:29581307). In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu-Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp (PubMed:29581307)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IG82;Q9VH73", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0004596 protein-N-terminal amino-acid acetyltransferase activity;GO:1905502 acetyl-CoA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008064 regulation of actin polymerization or depolymerization;GO:0018002 N-terminal peptidyl-glutamic acid acetylation;GO:0017190 N-terminal peptidyl-aspartic acid acetylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q59DX8-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P91645-1", "uniprot_id": [ { "id": "CAC1A_DROME", "url": "https://www.uniprot.org/uniprot/P91645", "type": "external" } ], "mass": 212471.0, "length": 1851, "protein_name": "Voltage-dependent calcium channel type A subunit alpha-1", "gene_name": "cac", "organism": "Fruit fly", "refseq_name": "cacophony, isoform O", "refseq_ac": [ { "id": "NP_001245639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245639", "type": "external" } ], "gene_names_uniprotkb": "cac; 13; CAC; CG1522; CG15928; CG43368; Ca-alpha1A; Ca[[V]]2.1; Cac1; Cactus; Cac; DMCA1A; Dmca1A; Dmcalpha1A; Dmel\\CG43368; Dmel_CG43368; EE171; H18; H47; L13; P18; alpha1A; cac1; cactus; cact; can; dCac1; dmca1A; l(1)11Aa; l(1)13; l(1)L13; ldg; nbA; nonB; opm18; opm47", "gene_names_refseq": "13; CAC; CG1522; CG15928; CG43368; Ca-alpha1A; Ca[[V]]2.1; Cac1; Cactus; Cac; DMCA1A; Dmca1A; Dmcalpha1A; Dmel\\CG43368; EE171; H18; H47; L13; P18; alpha1A; cac1; cactus; cact; cac; can; dCac1; dmca1A; l(1)11Aa; l(1)13; l(1)L13; ldg; nbA; nonB; opm18; opm47", "protein_names_uniprotkb": "Voltage-dependent calcium channel type A subunit alpha-1; Dmca1A; Protein cacophony; Protein nightblind A; Protein no-on-transient B", "protein_names_refseq": "CG43368-PO; cac-PO; cacaphony; cacophany; cacophony, isoform O; cacophony; cactus; calcium channel alpha1 subunit, type A; lamina-degeneration; lethal(1)11Aa; night blind A; nightblind A; no-on-transient B", "tax_id": 7227, "disease": "Lambert-Eaton myasthenic syndrome (Disease Ontology:DOID:0050214); childhood electroclinical syndrome (Disease Ontology:DOID:0050704); cerebellar ataxia (Disease Ontology:DOID:0050753); generalized dystonia (Disease Ontology:DOID:0050835); hereditary ataxia (Disease Ontology:DOID:0050951); spinocerebellar ataxia 6 (Disease Ontology:DOID:0050956); episodic ataxia type 2 (Disease Ontology:DOID:0050990); familial hemiplegic migraine (Disease Ontology:DOID:0060178); absence epilepsy (Disease Ontology:DOID:0070309); developmental and epileptic encephalopathy 42 (Disease Ontology:DOID:0080454); familial hemiplegic migraine 1 (Disease Ontology:DOID:0111181); developmental and epileptic encephalopathy 69 (Disease Ontology:DOID:0112205); migraine with aura (Disease Ontology:DOID:10024); childhood absence epilepsy (Disease Ontology:DOID:1825); epilepsy (Disease Ontology:DOID:1826); generalized epilepsy (Disease Ontology:DOID:1827); multiple sclerosis (Disease Ontology:DOID:2377); temporal lobe epilepsy (Disease Ontology:DOID:3328); brain edema (Disease Ontology:DOID:4724); migraine (Disease Ontology:DOID:6364)", "pathway": " (dme:Dmel_CG43368); (R-DME-422356)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10731132;10966106;12537568;12537572;12537573;12537574;16110336;17569856;17569867;19596851;25589440;26109356;26109357;28742085;8987815;9093853;9649530", "class_list": "", "function": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity). Probably encodes a dihydropyridine-insensitive current. Vital for survival to adulthood., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "O01713;O01714;Q76NR8;Q76NR9;Q76NS0;Q9VYR8", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005245 voltage-gated calcium channel activity;GO:0008331 high voltage-gated calcium channel activity;GO:0008332 low voltage-gated calcium channel activity", "go_cellular_component": "GO:0048787 presynaptic active zone membrane;GO:0016323 basolateral plasma membrane;GO:0031594 neuromuscular junction;GO:0016324 apical plasma membrane;GO:0048786 presynaptic active zone", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0042045 epithelial fluid transport;GO:0008344 adult locomotory behavior;GO:0016322 neuron remodeling;GO:0019722 calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P91645-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000100000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q27607-1", "uniprot_id": [ { "id": "DPOG1_DROME", "url": "https://www.uniprot.org/uniprot/Q27607", "type": "external" } ], "mass": 129828.0, "length": 1145, "protein_name": "DNA polymerase subunit gamma-1, mitochondrial", "gene_name": "PolG1", "organism": "Fruit fly", "refseq_name": "DNA polymerase gamma subunit 1", "refseq_ac": [ { "id": "NP_476821", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476821", "type": "external" } ], "gene_names_uniprotkb": "PolG1; CG8987; DNApol-gamma125; DNApol-gamma; DNApolG1; MtPolA; Polg; l(2)34Dc; l(2)br5; pol gamma-alpha; tam", "gene_names_refseq": "34Dc; AAC47658; BG:DS00941.6; CG8987; D-pol gamma-alpha; DNApol-gamma125; DNApol-gamma; DmPOLgammaA; DmPolgammaA; Dmel\\CG8987; MtPolA; POLGalpha; POLG; Pol gamma; PolG1; PolG; PolgA; Polgamma-alpha; Polgamma; Polg; Tam; anon-34Dc; br5; cDNA 2; l(2)34Dc; l(2)br14; l(2)br5; l(2)brS; mtDNA pol; mtPolA; pol gamma-alpha; pol gamma; polgamma-alpha; polgamma; tam", "protein_names_uniprotkb": "DNA polymerase subunit gamma-1, mitochondrial; 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-; DNA polymerase gamma subunit 1; Mitochondrial DNA polymerase catalytic subunit; Protein tamas", "protein_names_refseq": "CG8987-PA; DNA polymerase gamma 125kD; DNA polymerase gamma subunit 1; DNA polymerase gamma; PolG1-PA; alpha subunit; catalytic subunit of the mitochondrial DNA polymerase; catalytic(alpha)subunit; lethal 14 in the black-reduced region; lethal 5 in the black-reduced region; lethal(2)34Dc; mitochondrial gamma polymerase; mtDNA pol-gamma; mtDNA polymerase alpha; tamas", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); cerebellar ataxia (Disease Ontology:DOID:0050753); myelodysplastic syndrome (Disease Ontology:DOID:0050908); Alpers-Huttenlocher syndrome (Disease Ontology:DOID:0080122); mitochondrial DNA depletion syndrome 4b (Disease Ontology:DOID:0080123); sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (Disease Ontology:DOID:0111276); autosomal dominant progressive external ophthalmoplegia 1 (Disease Ontology:DOID:0111521); autosomal recessive progressive external ophthalmoplegia 1 (Disease Ontology:DOID:0111522); premature menopause (Disease Ontology:DOID:10787); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); Parkinson's disease (Disease Ontology:DOID:14330); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); multiple sclerosis (Disease Ontology:DOID:2377); bipolar disorder (Disease Ontology:DOID:3312); mood disorder (Disease Ontology:DOID:3324); progeria (Disease Ontology:DOID:3911); primary ovarian insufficiency (Disease Ontology:DOID:5426); peripheral nervous system disease (Disease Ontology:DOID:574); hepatocellular carcinoma (Disease Ontology:DOID:684); mitochondrial metabolism disease (Disease Ontology:DOID:700); mitochondrial encephalomyopathy (Disease Ontology:DOID:890)", "pathway": " (dme:Dmel_CG8987); (R-DME-9913635)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10471707;10731132;10930405;11917141;12537569;12537572;15537632;19924234;26554610;2671990;28318978;28430993;3095323;7499423;8798543;8884268;9153213", "class_list": "", "function": "As the catalytic component of the DNA polymerase gamma complex is involved in the replication of mitochondrial DNA (mtDNA) (PubMed:11917141, PubMed:15537632, PubMed:19924234, PubMed:28430993, PubMed:3095323, PubMed:7499423, PubMed:8798543). Has both 5'-3' DNA polymerase and a highly mispair-specific 3'-5' exonuclease activity (PubMed:15537632, PubMed:26554610, PubMed:2671990, PubMed:28430993, PubMed:7499423, PubMed:8798543). At the end of mtDNA replication DNA ends are ligated to produce a closed circular mtDNA molecule, its exonuclease activity is required for formation of these ligatable ends by preventing DNA synthesis from continuing past the 5'-end of downstream DNA into duplex DNA regions (PubMed:28430993). Does not possess DNA primase activity, does not catalyze strand displacement synthesis and does not contain a 5'-3' exonuclease activity to catalyze nick translation (PubMed:3095323). Important for promoting the elimination of paternal mitochondrial DNA during spermatogenesis, however its exact role in this function has not yet been identified and appears to be independent of its 3'-5'-exonuclease activity and only partially dependent on its DNA polymerase activity (PubMed:28318978)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 17, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5RIX0;Q8T4E6;Q94906;Q9V442", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008296 3'-5'-DNA exonuclease activity;GO:0003677 DNA binding;GO:0000166 nucleotide binding;GO:0008408 3'-5' exonuclease activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0042645 mitochondrial nucleoid;GO:0005760 gamma DNA polymerase complex", "go_biological_process": "GO:0030382 sperm mitochondrion organization;GO:0045004 DNA replication proofreading;GO:0007291 sperm individualization;GO:0006264 mitochondrial DNA replication;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q27607-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VVJ7-1", "uniprot_id": [ { "id": "Q9VVJ7_DROME", "url": "https://www.uniprot.org/uniprot/Q9VVJ7", "type": "external" } ], "mass": 19881.0, "length": 178, "protein_name": "Selenoprotein F", "gene_name": "Sep15", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_649000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649000", "type": "external" } ], "gene_names_uniprotkb": "Sep15; BcDNA:SD16138; CG7484; Dmel\\CG7484; Dmel_CG7484; Prise 8", "gene_names_refseq": "BcDNA:SD16138; CG7484; Dmel\\CG7484; Prise 8; Sep15", "protein_names_uniprotkb": "Selenoprotein F", "protein_names_refseq": "CG7484-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7484)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;16319061;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015038 glutathione disulfide oxidoreductase activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0012505 endomembrane system", "go_biological_process": "GO:0045454 cell redox homeostasis;GO:0051084 'de novo' post-translational protein folding", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VVJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VJ62-1", "uniprot_id": [ { "id": "NAF1_DROME", "url": "https://www.uniprot.org/uniprot/Q9VJ62", "type": "external" } ], "mass": 62270.0, "length": 564, "protein_name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "gene_name": "Dmel\\CG10341", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": [ { "id": "NP_609898", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609898", "type": "external" } ], "gene_names_uniprotkb": "Dmel\\CG10341; CG10341; Dmel_CG10341", "gene_names_refseq": "CG10341; Dmel\\CG10341", "protein_names_uniprotkb": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "protein_names_refseq": "CG10341-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "melanoma (Disease Ontology:DOID:1909)", "pathway": " (dme:Dmel_CG10341)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "RNA-binding protein required for the maturation of the box H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex and ribosome biogenesis. During assembly of the H/ACA snoRNP complex it associates with the complex and dissociates during complex maturation, becoming replaced by Gar1 to yield mature H/ACA snoRNP complex (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q961H3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005732 sno(s)RNA-containing ribonucleoprotein complex", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006364 rRNA processing;GO:0001522 pseudouridine synthesis;GO:0000493 box H/ACA snoRNP assembly;GO:0043489 RNA stabilization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VJ62-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9V780-1", "uniprot_id": [ { "id": "LAP1_DROME", "url": "https://www.uniprot.org/uniprot/Q9V780", "type": "external" } ], "mass": 96148.0, "length": 849, "protein_name": "Protein lap1", "gene_name": "Lap1", "organism": "Fruit fly", "refseq_name": "Lap1, isoform B", "refseq_ac": [ { "id": "NP_001188938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188938", "type": "external" } ], "gene_names_uniprotkb": "Lap1; CG10255; CT28815; Dmel\\CG10255; Dmel_CG10255; LRRC7; dLAP1; dLap1; dlap1", "gene_names_refseq": "CG10255; CT28815; Dmel\\CG10255; LRRC7; Lap1; dLAP1; dLap1; dlap1", "protein_names_uniprotkb": "Protein lap1", "protein_names_refseq": "CG10255-PB; Lap1, isoform B; Lap1-PB", "tax_id": 7227, "disease": "cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG10255)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "May have a role in assembling adherens junctions., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0015031 protein transport;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9V780-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VEN1-1", "uniprot_id": [ { "id": "FLNA_DROME", "url": "https://www.uniprot.org/uniprot/Q9VEN1", "type": "external" } ], "mass": 239181.0, "length": 2210, "protein_name": "Filamin-A", "gene_name": "cher", "organism": "Fruit fly", "refseq_name": "cheerio, isoform K", "refseq_ac": [ { "id": "NP_001262656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262656", "type": "external" } ], "gene_names_uniprotkb": "cher; CG3937; Cheerio; Cher; Dmel\\CG3937; Dmel_CG3937; FLN90; FLN; Fil; cheerio; dFil; filamin; joy; sko", "gene_names_refseq": "CG3937; Cheerio; Cher; Dmel\\CG3937; FLN90; FLN; Fil; cher; dFil; filamin; joy; sko", "protein_names_uniprotkb": "Filamin-A; ABP-280; Actin-binding protein 280; FLN-A; Filamin-1; Filamin1", "protein_names_refseq": "CG3937-PK; Filamin-1; Filamin-A; Filamin-B; cheerio, isoform K; cheerio; cher-PK; cherrio; filamin B; filamin isoform B; filamin-240; shi kong", "tax_id": 7227, "disease": "periventricular nodular heterotopia (Disease Ontology:DOID:0050454); atelosteogenesis (Disease Ontology:DOID:0050648); Boomerang dysplasia (Disease Ontology:DOID:0050680); spinal disease (Disease Ontology:DOID:0060564); bone development disease (Disease Ontology:DOID:0080006); myofibrillar myopathy 5 (Disease Ontology:DOID:0080096); X-linked chronic idiopathic intestinal pseudo-obstruction (Disease Ontology:DOID:0080681); spondylocarpotarsal synostosis syndrome (Disease Ontology:DOID:0090116); hypertrophic cardiomyopathy 26 (Disease Ontology:DOID:0110327); distal myopathy 4 (Disease Ontology:DOID:0111190); X-linked cardiac valvular dysplasia (Disease Ontology:DOID:0111765); otopalatodigital syndrome spectrum disorder (Disease Ontology:DOID:0111782); otopalatodigital syndrome type 1 (Disease Ontology:DOID:0111783); otopalatodigital syndrome type 2 (Disease Ontology:DOID:0111784); frontometaphyseal dysplasia 1 (Disease Ontology:DOID:0111786); Melnick-Needles syndrome (Disease Ontology:DOID:0111788); terminal osseous dysplasia (Disease Ontology:DOID:0112149); clubfoot (Disease Ontology:DOID:11836); dilated cardiomyopathy (Disease Ontology:DOID:12930); tuberous sclerosis (Disease Ontology:DOID:13515); thoracic aortic aneurysm (Disease Ontology:DOID:14004); Larsen syndrome (Disease Ontology:DOID:14764); epilepsy (Disease Ontology:DOID:1826); osteochondrodysplasia (Disease Ontology:DOID:2256); craniosynostosis (Disease Ontology:DOID:2340); myopathy (Disease Ontology:DOID:423); cleft palate (Disease Ontology:DOID:674); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); mitral valve prolapse (Disease Ontology:DOID:988)", "pathway": " (dme:Dmel_CG3937); (R-DME-114608); (R-DME-446353); (R-DME-5627123)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10477759;10556087;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;21857973;25589440;26109356;26109357", "class_list": "", "function": "Involved in the germline ring canal formation. May tether actin microfilament within the ovarian ring canal to the cell membrane. Contributes to actin microfilaments organization., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 29, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7KJX2;Q7KKC2;Q9GQV1;Q9U4I3;Q9U6C0;Q9U6C1", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0030018 Z disc", "go_biological_process": "GO:0051495 positive regulation of cytoskeleton organization;GO:0000278 mitotic cell cycle;GO:0048149 behavioral response to ethanol;GO:0008104 intracellular protein localization;GO:0007616 long-term memory", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VEN1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q24547-1", "uniprot_id": [ { "id": "STX1A_DROME", "url": "https://www.uniprot.org/uniprot/Q24547", "type": "external" } ], "mass": 33648.0, "length": 291, "protein_name": "Syntaxin-1A", "gene_name": "Syx1A", "organism": "Fruit fly", "refseq_name": "syntaxin 1A, isoform C", "refseq_ac": [ { "id": "NP_001303545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303545", "type": "external" } ], "gene_names_uniprotkb": "Syx1A; CG10716; CG18615; CG31136; CG5448; CT30033; Dm Syx1; DmSyx1A; Dmel\\CG31136; Dmel_CG31136; STX1; SYX 1A; SYX1A; SYX; Stx1a; Sx1A; Synx1A; Syn; Syt1A; Syx-1A; Syx1a; Syx1; SyxA; Syx; anon-EST:Gibbs4; anon-WO02059370.54; dSyx1; dsyn-1A; l(3)06737; syntaxin1A; syntaxin; synt; syt-1A; sytx; syx-1A; syx-1; syx1A; syx1; syx", "gene_names_refseq": "CG10716; CG18615; CG31136; CG5448; CT30033; Dm Syx1; DmSyx1A; Dmel\\CG31136; STX1; SYX 1A; SYX1A; SYX; Stx1a; Sx1A; Synx1A; Syn; Syt1A; Syx-1A; Syx1A; Syx1a; Syx1; SyxA; Syx; anon-EST:Gibbs4; anon-WO02059370.54; dSyx1; dsyn-1A; l(3)06737; syntaxin1A; syntaxin; synt; syt-1A; sytx; syx-1A; syx-1; syx1A; syx1; syx", "protein_names_uniprotkb": "Syntaxin-1A; dSynt1", "protein_names_refseq": "CG31136-PC; STX1A; Syx1A-PC; dsyntaxin-1A; synataxin 1; syntaxin 1A, isoform C; syntaxin 1A; syntaxin-1A; syntaxin1A; syntaxin1; syntx 1", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness (Disease Ontology:DOID:0050565); congenital diarrhea (Disease Ontology:DOID:0060774); generalized epilepsy with febrile seizures plus 9 (Disease Ontology:DOID:0111301); Hirschsprung's disease (Disease Ontology:DOID:10487); Creutzfeldt-Jakob disease (Disease Ontology:DOID:11949); disease of mental health (Disease Ontology:DOID:150); epilepsy (Disease Ontology:DOID:1826); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG31136); (R-DME-114516); (R-DME-181429); (R-DME-181430); (R-DME-199992); (R-DME-210500); (R-DME-212676); (R-DME-264642); (R-DME-449836); (R-DME-888590); (R-DME-9609523)", "pathway_count": 11, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;27323327;7609612;7834751", "class_list": "", "function": "Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation (PubMed:7834751). Essential for embryonic viability and development (PubMed:7834751). Required for coordinated peristaltic contractions (PubMed:7834751). Recruited by Unc-13-4B to secretory lysosome-related organelles (SLs) that are essential for tracheal lumen fusion between previously separate tracheal branches (anastomosis). Possibly promotes the intracellular fusion of the extending tracheal stalk cell lumens in tracheal fusion cells (Fcs) by interacting with complementary SNAREs (such as Syb) present in the apical membrane of the FC-FC interface and the membranes of the separate tracheal stalk cells (PubMed:27323327)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TX14;Q9VCD7", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043195 terminal bouton;GO:0005765 lysosomal membrane;GO:0012505 endomembrane system;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:1990182 exosomal secretion;GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0000281 mitotic cytokinesis;GO:0061025 membrane fusion", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q24547-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9V8Y9-1", "uniprot_id": [ { "id": "OB56H_DROME", "url": "https://www.uniprot.org/uniprot/Q9V8Y9", "type": "external" } ], "mass": 14978.0, "length": 134, "protein_name": "General odorant-binding protein 56h", "gene_name": "Obp56h", "organism": "Fruit fly", "refseq_name": "Odorant-binding protein 56h, isoform B", "refseq_ac": [ { "id": "NP_001188979", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188979", "type": "external" } ], "gene_names_uniprotkb": "Obp56h; 56h; CG13874; DmelObp56h; Dmel\\CG13874; Dmel_CG13874; OBP56h", "gene_names_refseq": "56h; CG13874; DmelObp56h; Dmel\\CG13874; OBP56h; Obp56h", "protein_names_uniprotkb": "General odorant-binding protein 56h", "protein_names_refseq": "CG13874-PB; Obp56h-PB; Odorant-binding protein 56h, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13874)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;11729153;12537568;12537572;12537573;12537574;16110336;17569856;17569867;17720903;25589440;26109356;26109357", "class_list": "", "function": "Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid (By similarity). May function in both olfactory and gustatory systems., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0JQ25;A9QI73;A9QI74;A9QI75;A9QI82;A9QI83;A9QI84;A9QI85;A9QI89;A9QI90;A9QI92;A9QI95;A9QIA1;A9QIA2;A9QIB4;A9QIB8;A9QIB9;A9QIC1;Q4V3H6", "ec_number_list": [], "go_molecular_function": "GO:0005549 odorant binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0042048 olfactory behavior;GO:0007608 sensory perception of smell;GO:0019236 response to pheromone;GO:1902436 negative regulation of male mating behavior;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9V8Y9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VI75-1", "uniprot_id": [ { "id": "PICAL_DROME", "url": "https://www.uniprot.org/uniprot/Q9VI75", "type": "external" } ], "mass": 49867.0, "length": 468, "protein_name": "Phosphatidylinositol-binding clathrin assembly protein LAP", "gene_name": "lap", "organism": "Fruit fly", "refseq_name": "like-AP180, isoform A", "refseq_ac": [ { "id": "NP_524252", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524252", "type": "external" } ], "gene_names_uniprotkb": "lap; AP180; BcDNA:GM10787; CG2520; Dmel\\CG2520; Dmel_CG2520; EP(3)3060; EP3060; LAP; Lap; dAP-3; l(3)neo34; sig", "gene_names_refseq": "AP180; BcDNA:GM10787; CG2520; Dmel\\CG2520; EP(3)3060; EP3060; LAP; Lap; dAP-3; l(3)neo34; lap/AP180; lap; sig", "protein_names_uniprotkb": "Phosphatidylinositol-binding clathrin assembly protein LAP; Like-AP180", "protein_names_refseq": "CG2520-PA; EP3060; Like-AP180; complementation group 12; lap-PA; like AP180; like-AP180, isoform A; saisoog", "tax_id": 7227, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); middle cerebral artery infarction (Disease Ontology:DOID:3525); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (dme:Dmel_CG2520); (R-DME-432722); (R-DME-8856825); (R-DME-8856828)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10731132;11239400;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9883738", "class_list": "", "function": "Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O96528;Q8MQM1", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005545 1-phosphatidylinositol binding;GO:0030276 clathrin binding;GO:0000149 SNARE binding;GO:0032050 clathrin heavy chain binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle;GO:0008021 synaptic vesicle;GO:0098894 extrinsic component of presynaptic endocytic zone membrane", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0006898 receptor-mediated endocytosis;GO:0006900 vesicle budding from membrane;GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VI75-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NFU0-1", "uniprot_id": [ { "id": "FMR1_DROME", "url": "https://www.uniprot.org/uniprot/Q9NFU0", "type": "external" } ], "mass": 76076.0, "length": 684, "protein_name": "Fragile X messenger ribonucleoprotein 1 homolog", "gene_name": "Fmr1", "organism": "Fruit fly", "refseq_name": "fragile X messenger ribonucleoprotein 1, isoform J", "refseq_ac": [ { "id": "NP_001303443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303443", "type": "external" } ], "gene_names_uniprotkb": "Fmr1; AT24755; BcDNA:GM08679; CG6203; DFMRP; DFmr1; Dfmr; Dmel\\CG6203; Dmel_CG6203; EP(3)3517; FMR1; FMRP; FMRp; FMR; FXR; Fmrp; cg6203; dFMR1; dFMRP; dFMR; dFXR1; dFXRP; dFXR; dFmr1; dFmrp; dfmr1; dfmr; dfxr1; dfxr; dmfr1; fmr1; fmr", "gene_names_refseq": "AT24755; BcDNA:GM08679; CG6203; DFMRP; DFmr1; Dfmr; Dmel\\CG6203; EP(3)3517; FMR1; FMRP; FMRp; FMR; FXR; Fmr1; Fmrp; cg6203; dFMR1; dFMRP; dFMR; dFXR1; dFXRP; dFXR; dFmr1; dFmrp; dfmr1; dfmr; dfxr1; dfxr; dmfr1; fmr1; fmr", "protein_names_uniprotkb": "Fragile X messenger ribonucleoprotein 1 homolog; FMRP; dFMR1", "protein_names_refseq": "CG6203-PJ; Fmr1-PJ; Fragile-X mental retardation 1; Fragile-X mental retardation protein; Fragile-X-related; cg 6203 gene product from transcript cg6203-rc; dFMR; dFmr1; drosophila fragile X mental retardation protein; fragile X mental retardation 1; fragile X mental retardation gene; fragile X mental retardation protein 1; fragile X mental retardation protein; fragile X mental retardation related 1; fragile X messenger ribonucleoprotein 1, isoform J; fragile X protein; fragile X related protein; fragile X retardation 1 protein; fragile X-related; fragile x related; fragile-X", "tax_id": 7227, "disease": "fragile X-associated tremor/ataxia syndrome (Disease Ontology:DOID:0050879); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); primary ovarian insufficiency 1 (Disease Ontology:DOID:0080857); congenital myopathy 9A (Disease Ontology:DOID:0081343); congenital myopathy 9B (Disease Ontology:DOID:0081344); fragile X syndrome (Disease Ontology:DOID:14261); alcohol use disorder (Disease Ontology:DOID:1574); transient cerebral ischemia (Disease Ontology:DOID:224); glucose metabolism disease (Disease Ontology:DOID:4194); malignant pleural mesothelioma (Disease Ontology:DOID:7474)", "pathway": " (dme:Dmel_CG6203)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10731132;11046149;11733059;12368261;12537568;12537572;12537573;12537574;12818175;14508492;15183715;16110336;16949822;17178403;17569856;17569867;18327897;25589440;26109356;26109357;30115809;33428246;35165263", "class_list": "", "function": "Polyribosome-associated RNA-binding protein that plays a role in neuronal development and synaptic plasticity through the regulation of protein synthesis of mRNAs (PubMed:11046149, PubMed:11733059, PubMed:12368261, PubMed:17178403). Acts as an mRNA regulator by mediating formation of some phase-separated membraneless compartment: undergoes liquid-liquid phase separation upon binding to target mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors (PubMed:35165263). Mainly acts as an activator of mRNA translation: promotes translation of stored mRNAs in oocytes (PubMed:30115809). Can also act as a negative translational regulator of specific mRNAs (PubMed:11733059, PubMed:17178403). Represses translation of the microtubule-associated protein futsch mRNA to regulate microtubule-dependent synaptic growth and function (PubMed:11733059). Localizes to specific N6-methyladenosine (m6A)-containing RNAs as part of a complex with the m6A reader Ythdf and thereby regulates axonal growth in the mushroom bodies and neuromuscular junctions (PubMed:33428246). Specifically recognizes and binds a subset of N6-methyladenosine (m6A)-containing mRNAs in embryos, promoting formation of a phase-separated membraneless compartment that mediates degradation of maternal mRNAs (PubMed:35165263). May also be involved in microRNA (miRNA)-mediated translational suppression as part of the RNA-induced silencing complex (RISC) (PubMed:12368261, PubMed:14508492). Required for stability of the central pair of microtubules in the spermatid axoneme (PubMed:15183715). Regulates photoreceptor structure and neuromuscular junction (NMJ) neurotransmission in the eye (PubMed:11733059, PubMed:17178403). During embryogenesis, involved in germline fate determination (PubMed:16949822)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V2M8;Q8INM7;Q8T0M0;Q8WQ60;Q95P21;Q9GSG3;Q9TVY4;Q9VH27", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0042802 identical protein binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0043204 perikaryon", "go_biological_process": "GO:0008049 male courtship behavior;GO:0048621 post-embryonic digestive tract morphogenesis;GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0042048 olfactory behavior;GO:0072553 terminal button organization", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q9NFU0-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000100000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9VFE4-1", "uniprot_id": [ { "id": "RS5B_DROME", "url": "https://www.uniprot.org/uniprot/Q9VFE4", "type": "external" } ], "mass": 25716.0, "length": 230, "protein_name": "Small ribosomal subunit protein uS7B", "gene_name": "RpS5b", "organism": "Fruit fly", "refseq_name": "ribosomal protein S5b, isoform A", "refseq_ac": [ { "id": "NP_650407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650407", "type": "external" } ], "gene_names_uniprotkb": "RpS5b; 142157_at; CG7014; Dmel\\CG7014; Dmel_CG7014; RPS5b; RS5B_DROME; RbS5b; RpS5; S5b; rps5b", "gene_names_refseq": "142157_at; CG7014; Dmel\\CG7014; RPS5b; RS5B_DROME; RbS5b; RpS5b; S5b; rps5b", "protein_names_uniprotkb": "Small ribosomal subunit protein uS7B; 40S ribosomal protein S5b", "protein_names_refseq": "CG7014-PA; RpS5b-PA; ribosomal protein S5b, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7014); (R-DME-156827); (R-DME-1799339); (R-DME-6791226); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702); (R-DME-72706); (R-DME-975956); (R-DME-975957); (R-DME-9954714); (R-DME-9954716)", "pathway_count": 13, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome;GO:0003723 RNA binding", "go_cellular_component": "GO:0005840 ribosome;GO:0022627 cytosolic small ribosomal subunit;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VFE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KRY7-1", "uniprot_id": [ { "id": "SCRIB_DROME", "url": "https://www.uniprot.org/uniprot/Q7KRY7", "type": "external" } ], "mass": 200440.0, "length": 1851, "protein_name": "Protein lap4", "gene_name": "scrib", "organism": "Fruit fly", "refseq_name": "scribble, isoform I", "refseq_ac": [ { "id": "NP_001014669", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014669", "type": "external" } ], "gene_names_uniprotkb": "scrib; 05; CG31082; CG42614; CG43398; CG5462; CG5467; CT17324; Dmel\\CG43398; Dmel_CG43398; Lap4; MENE (3R)-F; SCRIB; SCR; Scb; Scrb; Scribble; Scrib; ird15; ird; l(3)673; l(3)S042405; l(3)c00119; l(3)j7B3; scrb; smi97B; smi; vart", "gene_names_refseq": "0424/05; CG31082; CG42614; CG43398; CG5462; CG5467; CT17324; Dmel\\CG43398; Lap4; MENE (3R)-F; SCRIB; SCR; Scb; Scrb; Scribble; Scrib; ird15; ird; l(3)673; l(3)S042405; l(3)c00119; l(3)j7B3; scrb; scrib; smi97B; vart", "protein_names_uniprotkb": "Protein lap4; Protein scribble; Protein smell-impaired", "protein_names_refseq": "CG43398-PI; gp150-like; immune response deficient 15; lethal (3) c00119; scrib-PI; scribble, isoform I; scribbled; scribbles; scribble; smell impaired 97B; vartul", "tax_id": 7227, "disease": "benign neoplasm (Disease Ontology:DOID:0060072); cancer (Disease Ontology:DOID:162); kidney cancer (Disease Ontology:DOID:263); carcinoma (Disease Ontology:DOID:305)", "pathway": " (dme:Dmel_CG43398); (R-DME-438066); (R-DME-6798695); (R-DME-9013406)", "pathway_count": 4, "publication_count": 20, "publication_id_list": "10688207;10731132;10884224;11578873;12537568;12537569;12537572;12537573;12537574;12930751;16110336;17569856;17569867;18327897;20146544;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "Required for polarization of the embryonic, imaginal disk and follicular epithelia. Specifically restricts apical membrane determinants to the apical cell surface; acts to exclude crb from the basolateral domain and define adherens junction position. Regulates cellular growth and differentiation; acts as a tumor suppressor. Essential for odor guided behavior., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4K7L2;A4V3G5;Q59DT7;Q59DT8;Q6AWK8;Q7K9X1;Q7KA36;Q86QS7;Q86QS8;Q86QS9;Q86QT0;Q8IMR8;Q8IMR9;Q8T003;Q95SV4;Q9VBE4", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005912 adherens junction;GO:0005938 cell cortex;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0001708 cell fate specification;GO:0042048 olfactory behavior;GO:0016332 establishment or maintenance of polarity of embryonic epithelium;GO:0048749 compound eye development;GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q7KRY7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000100000000000.0100000001001.001.00000", "kg_view_protein": true } ]