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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KFY6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFZ1-1", "uniprot_id": [ { "id": "A0A9J7KFZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFZ1", "type": "external" } ], "mass": 58356.0, "length": 520, "protein_name": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "gene_name": "LOC113838364", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "refseq_ac": [ { "id": "XP_035309459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309459", "type": "external" } ], "gene_names_uniprotkb": "LOC113838364", "gene_names_refseq": "LOC113838364", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "protein_names_refseq": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838364)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KFZ1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFZ3-1", "uniprot_id": [ { "id": "A0A9J7KFZ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFZ3", "type": "external" } ], "mass": 82320.0, "length": 722, "protein_name": "E3 ubiquitin-protein ligase RNF216-like isoform X2", "gene_name": "LOC100765983", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF216-like isoform X2", "refseq_ac": [ { "id": "XP_035309663", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309663", "type": "external" } ], "gene_names_uniprotkb": "LOC100765983", "gene_names_refseq": "LOC100765983", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF216-like isoform X2", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF216-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765983)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 14% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276949.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the carboxy end., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016740 transferase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KFZ3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KG10-1", "uniprot_id": [ { "id": "A0A9J7KG10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KG10", "type": "external" } ], "mass": 11996.0, "length": 105, "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1-like", "gene_name": "LOC100757965", "organism": "Hamster", "refseq_name": "ubiquitin-conjugating enzyme E2 variant 1-like", "refseq_ac": [ { "id": "XP_035309521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309521", "type": "external" } ], "gene_names_uniprotkb": "LOC100757965", "gene_names_refseq": "LOC100757965", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 variant 1-like", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 variant 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100757965)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277175.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277352.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277421.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0061578 K63-linked deubiquitinase activity;GO:0140492 metal-dependent deubiquitinase activity", "go_cellular_component": "GO:0005768 endosome;GO:0032154 cleavage furrow", "go_biological_process": "GO:0006508 proteolysis;GO:0070536 protein K63-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KG31-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KG35-1", "uniprot_id": [ { "id": "A0A9J7KG35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KG35", "type": "external" } ], "mass": 68404.0, "length": 609, "protein_name": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "gene_name": "LOC113838896", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "refseq_ac": [ { "id": "XP_035309834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309834", "type": "external" } ], "gene_names_uniprotkb": "LOC113838896", "gene_names_refseq": "LOC113838896", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "protein_names_refseq": "LOW QUALITY PROTEIN: GRB2-associated-binding protein 2-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838896)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 12% of CDS bases frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277438.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the carboxy end., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KG35-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KG46-1", "uniprot_id": [ { "id": "A0A9J7KG46_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KG46", "type": "external" } ], "mass": 8634.0, "length": 79, "protein_name": "Ly6/PLAUR domain-containing protein 1-like", "gene_name": "LOC118239799", "organism": "Hamster", "refseq_name": "ly6/PLAUR domain-containing protein 1-like", "refseq_ac": [ { "id": "XP_035309657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309657", "type": "external" } ], "gene_names_uniprotkb": "LOC118239799", "gene_names_refseq": "LOC118239799", "protein_names_uniprotkb": "Ly6/PLAUR domain-containing protein 1-like", "protein_names_refseq": "ly6/PLAUR domain-containing protein 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:118239799)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276933.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277021.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277121.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277207.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023277415.1) and transcript sequence (IACG01158486.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613712.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0015078 proton transmembrane transporter activity;GO:0005452 solute:inorganic anion antiporter activity;GO:0015108 chloride transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1900407 regulation of cellular response to oxidative stress;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HW53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061HY45-1", "uniprot_id": [ { "id": "A0A061HY45_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061HY45", "type": "external" } ], "mass": 113507.0, "length": 1023, "protein_name": "Histone lysine demethylase PHF8", "gene_name": "Phf8", "organism": "Hamster", "refseq_name": "histone lysine demethylase PHF8 isoform X1", "refseq_ac": [ { "id": "XP_007639121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639121", "type": "external" } ], "gene_names_uniprotkb": "Phf8", "gene_names_refseq": "Phf8", "protein_names_uniprotkb": "Histone lysine demethylase PHF8; 1.14.11.65; PHD finger protein 8; [histone H3]-dimethyl-L-lysine(9) demethylase PHF8", "protein_names_refseq": "histone lysine demethylase PHF8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756628)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613780.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" }, { "id": "1.14.99.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008168 methyltransferase activity;GO:0140680 histone H3K36me/H3K36me2 demethylase activity;GO:0140683 histone H3K9me/H3K9me2 demethylase activity;GO:0035575 histone H4K20 demethylase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0032259 methylation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HY45-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061HVZ9-1", "uniprot_id": [ { "id": "A0A061HVZ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061HVZ9", "type": "external" } ], "mass": 35888.0, "length": 313, "protein_name": "Apolipoprotein E", "gene_name": "LOC113837959", "organism": "Hamster", "refseq_name": "apolipoprotein E", "refseq_ac": [ { "id": "XP_027286676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286676", "type": "external" } ], "gene_names_uniprotkb": "LOC113837959; Apoe", "gene_names_refseq": "Apoe", "protein_names_uniprotkb": "Apolipoprotein E", "protein_names_refseq": "apolipoprotein E", "tax_id": 10029, "disease": "", "pathway": " (cge:100773810); (cge:113837959)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008201 heparin binding;GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0034364 high-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron;GO:0034362 low-density lipoprotein particle;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0090181 regulation of cholesterol metabolic process;GO:0033344 cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HVZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061HWS9-1", "uniprot_id": [ { "id": "A0A061HWS9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061HWS9", "type": "external" } ], "mass": 21539.0, "length": 186, "protein_name": "ADP-ribosylation factor-like protein 8B", "gene_name": "Arl8b", "organism": "Hamster", "refseq_name": "ADP-ribosylation factor-like protein 8B", "refseq_ac": [ { "id": "XP_003498779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498779", "type": "external" } ], "gene_names_uniprotkb": "Arl8b", "gene_names_refseq": "Arl8b", "protein_names_uniprotkb": "ADP-ribosylation factor-like protein 8B", "protein_names_refseq": "ADP-ribosylation factor-like protein 8B", "tax_id": 10029, "disease": "", "pathway": " (cge:100765619)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613701.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0048487 beta-tubulin binding;GO:0019003 GDP binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0045202 synapse;GO:0051233 spindle midzone;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0008089 anterograde axonal transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HWS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I033-1", "uniprot_id": [ { "id": "A0A061I033_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I033", "type": "external" } ], "mass": 48189.0, "length": 423, "protein_name": "Stress-activated protein kinase JNK", "gene_name": "Mapk9", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase 9 isoform X2", "refseq_ac": [ { "id": "XP_027283456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283456", "type": "external" } ], "gene_names_uniprotkb": "Mapk9", "gene_names_refseq": "Mapk9", "protein_names_uniprotkb": "Stress-activated protein kinase JNK; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 9 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764964)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004705 JUN kinase activity;GO:0106310 protein serine kinase activity;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0048511 rhythmic process;GO:0010744 positive regulation of macrophage derived foam cell differentiation;GO:0031398 positive regulation of protein ubiquitination;GO:0042752 regulation of circadian rhythm;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I033-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061HY35-1", "uniprot_id": [ { "id": "A0A061HY35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061HY35", "type": "external" } ], "mass": 24535.0, "length": 226, "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "Psmd10", "organism": "Hamster", "refseq_name": "26S proteasome non-ATPase regulatory subunit 10 isoform X1", "refseq_ac": [ { "id": "XP_003512486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512486", "type": "external" } ], "gene_names_uniprotkb": "Psmd10", "gene_names_refseq": "Psmd10", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; Gankyrin", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 10 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751016)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615462.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis., [UniProtKB, UniProtKB]; Acts as an oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53. Overexpression is leading to phosphorylation of RB1 and proteasomal degradation of RB1. Regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4. Facilitates binding of MDM2 to p53/TP53 and the mono- and polyubiquitination of p53/TP53 by MDM2 suggesting a function in targeting the TP53:MDM2 complex to the 26S proteasome. Involved in p53-independent apoptosis. Involved in regulation of NF-kappa-B by retaining it in the cytoplasm. Binds to the NF-kappa-B component RELA and accelerates its XPO1/CRM1-mediated nuclear export., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0000502 proteasome complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030307 positive regulation of cell growth;GO:0006915 apoptotic process;GO:0031398 positive regulation of protein ubiquitination;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HY35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061HYJ0-1", "uniprot_id": [ { "id": "A0A061HYJ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061HYJ0", "type": "external" } ], "mass": 75692.0, "length": 669, "protein_name": "Synaptotagmin-like protein 4", "gene_name": "Sytl4", "organism": "Hamster", "refseq_name": "synaptotagmin-like protein 4 isoform X1", "refseq_ac": [ { "id": "XP_027288651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288651", "type": "external" } ], "gene_names_uniprotkb": "Sytl4", "gene_names_refseq": "Sytl4", "protein_names_uniprotkb": "Synaptotagmin-like protein 4; Exophilin-2; Granuphilin", "protein_names_refseq": "synaptotagmin-like protein 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770139)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008270 zinc ion binding;GO:0031267 small GTPase binding;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0030141 secretory granule;GO:0030658 transport vesicle membrane;GO:0070382 exocytic vesicle", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0071985 multivesicular body sorting pathway;GO:0006886 intracellular protein transport;GO:0050714 positive regulation of protein secretion;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HYJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061HZC8-1", "uniprot_id": [ { "id": "A0A061HZC8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061HZC8", "type": "external" } ], "mass": 65612.0, "length": 570, "protein_name": "NADPH oxidase 2", "gene_name": "LOC100760802", "organism": "Hamster", "refseq_name": "cytochrome b-245 heavy chain", "refseq_ac": [ { "id": "XP_035305927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305927", "type": "external" } ], "gene_names_uniprotkb": "LOC100760802", "gene_names_refseq": "LOC100760802", "protein_names_uniprotkb": "NADPH oxidase 2; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b-245 heavy chain; Heme-binding membrane glycoprotein gp91phox; Neutrophil cytochrome b 91 kDa polypeptide; gp91-1; gp91-phox; p22 phagocyte B-cytochrome", "protein_names_refseq": "cytochrome b-245 heavy chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100760802)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox. NADPH oxidase complex assembly is impaired through interaction with NRROS., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.1", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0071949 FAD binding;GO:0020037 heme binding", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0045335 phagocytic vesicle;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0034220 monoatomic ion transmembrane transport;GO:0045730 respiratory burst;GO:0042554 superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061HZC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I2H1-1", "uniprot_id": [ { "id": "A0A061I2H1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I2H1", "type": "external" } ], "mass": 108857.0, "length": 979, "protein_name": "Next to BRCA1 gene 1 protein", "gene_name": "Nbr1", "organism": "Hamster", "refseq_name": "next to BRCA1 gene 1 protein isoform X1", "refseq_ac": [ { "id": "XP_007643363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643363", "type": "external" } ], "gene_names_uniprotkb": "Nbr1", "gene_names_refseq": "Nbr1", "protein_names_uniprotkb": "Next to BRCA1 gene 1 protein; Neighbor of BRCA1 gene 1 protein", "protein_names_refseq": "next to BRCA1 gene 1 protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771299)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614078.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ubiquitin-binding autophagy adapter that participates in different processes including host defense or intracellular homeostasis. Possesses a double function during the selective autophagy by acting as a shuttle bringing ubiquitinated proteins to autophagosomes and also by participating in the formation of protein aggregates. Plays a role in the regulation of the innate immune response by modulating type I interferon production and targeting ubiquitinated IRF3 for autophagic degradation. In response to oxidative stress, promotes an increase in SQSTM1 levels, phosphorylation, and body formation by preventing its autophagic degradation. In turn, activates the KEAP1-NRF2/NFE2L2 antioxidant pathway. Also plays non-autophagy role by mediating the shuttle of IL-12 to late endosome for subsequent secretion., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043130 ubiquitin binding;GO:0051019 mitogen-activated protein kinase binding", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0030017 sarcomere;GO:0005776 autophagosome;GO:0000407 phagophore assembly site;GO:0070013 intracellular organelle lumen", "go_biological_process": "GO:0016236 macroautophagy;GO:0030500 regulation of bone mineralization;GO:0045668 negative regulation of osteoblast differentiation;GO:0032872 regulation of stress-activated MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I2H1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I0U3-1", "uniprot_id": [ { "id": "A0A061I0U3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I0U3", "type": "external" } ], "mass": 38532.0, "length": 354, "protein_name": "Arginase", "gene_name": "Arg2", "organism": "Hamster", "refseq_name": "arginase-2, mitochondrial", "refseq_ac": [ { "id": "XP_003498314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498314", "type": "external" } ], "gene_names_uniprotkb": "Arg2", "gene_names_refseq": "Arg2", "protein_names_uniprotkb": "Arginase; 3.5.3.1", "protein_names_refseq": "arginase-2, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100760459)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613686.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003498314.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.5.3.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.17", "type": "external" }, { "id": "3.5.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.7", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004053 arginase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0032700 negative regulation of interleukin-17 production;GO:0032651 regulation of interleukin-1 beta production;GO:0032720 negative regulation of tumor necrosis factor production;GO:0000050 urea cycle;GO:0001657 ureteric bud development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I0U3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I2U6-1", "uniprot_id": [ { "id": "A0A061I2U6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I2U6", "type": "external" } ], "mass": 41429.0, "length": 366, "protein_name": "Apolipoprotein A-V", "gene_name": "Apoa5", "organism": "Hamster", "refseq_name": "apolipoprotein A-V", "refseq_ac": [ { "id": "XP_035300470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300470", "type": "external" } ], "gene_names_uniprotkb": "Apoa5", "gene_names_refseq": "Apoa5", "protein_names_uniprotkb": "Apolipoprotein A-V; Apolipoprotein A5; Regeneration-associated protein 3", "protein_names_refseq": "apolipoprotein A-V", "tax_id": 10029, "disease": "", "pathway": " (cge:100772884)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0034364 high-density lipoprotein particle;GO:0005770 late endosome;GO:0034361 very-low-density lipoprotein particle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0033344 cholesterol efflux;GO:0055090 acylglycerol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I2U6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I436-1", "uniprot_id": [ { "id": "A0A061I436_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I436", "type": "external" } ], "mass": 38735.0, "length": 342, "protein_name": "L-Fucosyltransferase", "gene_name": "LOC113836307", "organism": "Hamster", "refseq_name": "galactoside alpha-(1,2)-fucosyltransferase 2", "refseq_ac": [ { "id": "XP_035302848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302848", "type": "external" } ], "gene_names_uniprotkb": "LOC113836307", "gene_names_refseq": "LOC113836307", "protein_names_uniprotkb": "L-Fucosyltransferase; 2.4.1.-", "protein_names_refseq": "galactoside alpha-(1,2)-fucosyltransferase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:113836307)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I436-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I578-1", "uniprot_id": [ { "id": "A0A061I578_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I578", "type": "external" } ], "mass": 152124.0, "length": 1332, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp8b3", "organism": "Hamster", "refseq_name": "phospholipid-transporting ATPase IK", "refseq_ac": [ { "id": "XP_027275139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275139", "type": "external" } ], "gene_names_uniprotkb": "Atp8b3", "gene_names_refseq": "Atp8b3", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "phospholipid-transporting ATPase IK", "tax_id": 10029, "disease": "", "pathway": " (cge:100757984)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0002080 acrosomal membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I578-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I6J1-1", "uniprot_id": [ { "id": "A0A061I6J1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I6J1", "type": "external" } ], "mass": 10631.0, "length": 99, "protein_name": "Apolipoprotein C-III", "gene_name": "Apoc3", "organism": "Hamster", "refseq_name": "apolipoprotein C-III", "refseq_ac": [ { "id": "XP_035300104", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300104", "type": "external" } ], "gene_names_uniprotkb": "Apoc3", "gene_names_refseq": "Apoc3", "protein_names_uniprotkb": "Apolipoprotein C-III; Apolipoprotein C3", "protein_names_refseq": "apolipoprotein C-III", "tax_id": 10029, "disease": "", "pathway": " (cge:100774705)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0055102 lipase inhibitor activity;GO:0070653 high-density lipoprotein particle receptor binding", "go_cellular_component": "GO:0034363 intermediate-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0034366 spherical high-density lipoprotein particle;GO:0042627 chylomicron", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0045717 negative regulation of fatty acid biosynthetic process;GO:0033344 cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I6J1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061I8T7-1", "uniprot_id": [ { "id": "A0A061I8T7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061I8T7", "type": "external" } ], "mass": 52643.0, "length": 517, "protein_name": "RNA-binding protein FUS", "gene_name": "Fus", "organism": "Hamster", "refseq_name": "RNA-binding protein FUS isoform X1", "refseq_ac": [ { "id": "XP_027260321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260321", "type": "external" } ], "gene_names_uniprotkb": "Fus", "gene_names_refseq": "Fus", "protein_names_uniprotkb": "RNA-binding protein FUS", "protein_names_refseq": "RNA-binding protein FUS isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756868)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Also binds its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005654 nucleoplasm;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0008380 RNA splicing;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051260 protein homooligomerization;GO:1990000 amyloid fibril formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061I8T7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IAS3-1", "uniprot_id": [ { "id": "A0A061IAS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IAS3", "type": "external" } ], "mass": 31692.0, "length": 271, "protein_name": "Elongation of very long chain fatty acids protein 3", "gene_name": "Elovl3", "organism": "Hamster", "refseq_name": "elongation of very long chain fatty acids protein 3", "refseq_ac": [ { "id": "XP_027263278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263278", "type": "external" } ], "gene_names_uniprotkb": "Elovl3; ELOVL3", "gene_names_refseq": "Elovl3", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 3; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL3; ELOVL FA elongase 3; ELOVL fatty acid elongase 3; Very long chain 3-ketoacyl-CoA synthase 3; Very long chain 3-oxoacyl-CoA synthase 3", "protein_names_refseq": "elongation of very long chain fatty acids protein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100774317)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IAS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IBC7-1", "uniprot_id": [ { "id": "A0A061IBC7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IBC7", "type": "external" } ], "mass": 47366.0, "length": 432, "protein_name": "Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "Acadsb", "organism": "Hamster", "refseq_name": "short/branched chain specific acyl-CoA dehydrogenase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027264957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264957", "type": "external" } ], "gene_names_uniprotkb": "Acadsb", "gene_names_refseq": "Acadsb", "protein_names_uniprotkb": "Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial; 1.3.8.1; 1.3.8.5; 2-methyl branched chain acyl-CoA dehydrogenase; 2-methylbutyryl-coenzyme A dehydrogenase", "protein_names_refseq": "short/branched chain specific acyl-CoA dehydrogenase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766828)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA). Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (butanoyl-CoA). Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.8.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.1", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "1.3.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.7", "type": "external" }, { "id": "1.3.8.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.8", "type": "external" }, { "id": "1.3.8.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.4", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0050660 flavin adenine dinucleotide binding;GO:0003853 short-chain 2-methyl fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006550 L-isoleucine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IBC7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IC63-1", "uniprot_id": [ { "id": "A0A061IC63_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IC63", "type": "external" } ], "mass": 57995.0, "length": 503, "protein_name": "Aromatase", "gene_name": "LOC100769024", "organism": "Hamster", "refseq_name": "aromatase", "refseq_ac": [ { "id": "XP_003508831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508831", "type": "external" } ], "gene_names_uniprotkb": "LOC100769024", "gene_names_refseq": "LOC100769024", "protein_names_uniprotkb": "Aromatase; 1.14.14.14; CYPXIX; Cytochrome P-450AROM; Cytochrome P450 19A1; Estrogen synthase", "protein_names_refseq": "aromatase", "tax_id": 10029, "disease": "", "pathway": " (cge:100769024)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614584.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070330 aromatase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008395 steroid hydroxylase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006710 androgen catabolic process;GO:2000866 positive regulation of estradiol secretion;GO:0032355 response to estradiol;GO:0006703 estrogen biosynthetic process;GO:0008585 female gonad development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IC63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061ICP0-1", "uniprot_id": [ { "id": "A0A061ICP0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061ICP0", "type": "external" } ], "mass": 17749.0, "length": 161, "protein_name": "Ragulator complex protein LAMTOR1", "gene_name": "Lamtor1", "organism": "Hamster", "refseq_name": "ragulator complex protein LAMTOR1", "refseq_ac": [ { "id": "XP_003514335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514335", "type": "external" } ], "gene_names_uniprotkb": "Lamtor1", "gene_names_refseq": "Lamtor1", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR1; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1", "protein_names_refseq": "ragulator complex protein LAMTOR1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750343)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616493.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0051020 GTPase binding;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0071986 Ragulator complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0043410 positive regulation of MAPK cascade;GO:0001919 regulation of receptor recycling;GO:0042632 cholesterol homeostasis;GO:0001558 regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061ICP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IDT3-1", "uniprot_id": [ { "id": "A0A061IDT3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IDT3", "type": "external" } ], "mass": 32469.0, "length": 288, "protein_name": "DNA repair protein complementing XP-A cells homolog", "gene_name": "Xpa", "organism": "Hamster", "refseq_name": "DNA repair protein complementing XP-A cells homolog isoform X4", "refseq_ac": [ { "id": "XP_027258960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258960", "type": "external" } ], "gene_names_uniprotkb": "Xpa", "gene_names_refseq": "Xpa", "protein_names_uniprotkb": "DNA repair protein complementing XP-A cells homolog; Xeroderma pigmentosum group A-complementing protein homolog", "protein_names_refseq": "DNA repair protein complementing XP-A cells homolog isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100689196)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0003684 damaged DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0000110 nucleotide-excision repair factor 1 complex;GO:0016604 nuclear body;GO:0005662 DNA replication factor A complex", "go_biological_process": "GO:0006284 base-excision repair;GO:0034504 protein localization to nucleus;GO:0070914 UV-damage excision repair;GO:0000715 nucleotide-excision repair, DNA damage recognition;GO:0009650 UV protection", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IDT3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IDT8-1", "uniprot_id": [ { "id": "A0A061IDT8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IDT8", "type": "external" } ], "mass": 22794.0, "length": 209, "protein_name": "Protein lin-28 homolog A", "gene_name": "Lin28a", "organism": "Hamster", "refseq_name": "protein lin-28 homolog A", "refseq_ac": [ { "id": "XP_035294791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294791", "type": "external" } ], "gene_names_uniprotkb": "Lin28a", "gene_names_refseq": "Lin28a", "protein_names_uniprotkb": "Protein lin-28 homolog A", "protein_names_refseq": "protein lin-28 homolog A", "tax_id": 10029, "disease": "", "pathway": " (cge:100767698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0008270 zinc ion binding;GO:0035198 miRNA binding;GO:0002151 G-quadruplex RNA binding;GO:0070883 pre-miRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005791 rough endoplasmic reticulum;GO:0005829 cytosol;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:2000767 positive regulation of cytoplasmic translation;GO:0048863 stem cell differentiation;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0071333 cellular response to glucose stimulus;GO:0032008 positive regulation of TOR signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IDT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IDW8-1", "uniprot_id": [ { "id": "A0A061IDW8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IDW8", "type": "external" } ], "mass": 371011.0, "length": 3372, "protein_name": "Versican core protein", "gene_name": "Vcan", "organism": "Hamster", "refseq_name": "versican core protein isoform X1", "refseq_ac": [ { "id": "XP_027257572", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257572", "type": "external" } ], "gene_names_uniprotkb": "Vcan", "gene_names_refseq": "Vcan", "protein_names_uniprotkb": "Versican core protein; Chondroitin sulfate proteoglycan core protein 2; Large fibroblast proteoglycan; PG-M", "protein_names_refseq": "versican core protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766891)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0005540 hyaluronic acid binding", "go_cellular_component": "GO:0033165 interphotoreceptor matrix;GO:0005615 extracellular space;GO:0045202 synapse;GO:0001750 photoreceptor outer segment;GO:0072534 perineuronal net", "go_biological_process": "GO:0007155 cell adhesion;GO:0007417 central nervous system development;GO:0001501 skeletal system development;GO:0002052 positive regulation of neuroblast proliferation;GO:0010001 glial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IDW8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IEQ5-1", "uniprot_id": [ { "id": "A0A061IEQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IEQ5", "type": "external" } ], "mass": 69922.0, "length": 627, "protein_name": "Sphingomyelin phosphodiesterase", "gene_name": "Smpd1", "organism": "Hamster", "refseq_name": "sphingomyelin phosphodiesterase", "refseq_ac": [ { "id": "XP_003515575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515575", "type": "external" } ], "gene_names_uniprotkb": "Smpd1", "gene_names_refseq": "Smpd1", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase; 3.1.4.12", "protein_names_refseq": "sphingomyelin phosphodiesterase", "tax_id": 10029, "disease": "", "pathway": " (cge:100760557)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 158 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003618335.1) and transcript sequence (IACG01089066.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Converts sphingomyelin to ceramide. Exists as two enzymatic forms that arise from alternative trafficking of a single protein precursor, one that is targeted to the endolysosomal compartment, whereas the other is released extracellularly. However, in response to various forms of stress, lysosomal exocytosis may represent a major source of the secretory form., [UniProtKB, UniProtKB]; In the lysosomes, converts sphingomyelin to ceramide. Plays an important role in the export of cholesterol from the intraendolysosomal membranes. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Modulates stress-induced apoptosis through the production of ceramide., [UniProtKB, UniProtKB]; This form is generated following cleavage by CASP7 in the extracellular milieu in response to bacterial infection. It shows increased ability to convert sphingomyelin to ceramide and promotes plasma membrane repair. Plasma membrane repair by ceramide counteracts the action of gasdermin-D (GSDMD) perforin (PRF1) pores that are formed in response to bacterial infection., [UniProtKB, UniProtKB]; When secreted, modulates cell signaling with its ability to reorganize the plasma membrane by converting sphingomyelin to ceramide. Secreted form is increased in response to stress and inflammatory mediators such as IL1B, IFNG or TNF as well as upon infection with bacteria and viruses. Produces the release of ceramide in the outer leaflet of the plasma membrane playing a central role in host defense. Ceramide reorganizes these rafts into larger signaling platforms that are required to internalize P.aeruginosa, induce apoptosis and regulate the cytokine response in infected cells. In wounded cells, the lysosomal form is released extracellularly in the presence of Ca(2+) and promotes endocytosis and plasma membrane repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.12", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016798 hydrolase activity, acting on glycosyl bonds;GO:0061750 acid sphingomyelin phosphodiesterase activity;GO:0034480 phosphatidylcholine phospholipase C activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005811 lipid droplet;GO:0016020 membrane;GO:0005764 lysosome", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0046513 ceramide biosynthetic process;GO:0006685 sphingomyelin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IEQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IFI3-1", "uniprot_id": [ { "id": "A0A061IFI3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IFI3", "type": "external" } ], "mass": 80003.0, "length": 735, "protein_name": "Peroxisomal multifunctional enzyme type 2", "gene_name": "Hsd17b4", "organism": "Hamster", "refseq_name": "peroxisomal multifunctional enzyme type 2 isoform X2", "refseq_ac": [ { "id": "XP_027256683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256683", "type": "external" } ], "gene_names_uniprotkb": "Hsd17b4", "gene_names_refseq": "Hsd17b4", "protein_names_uniprotkb": "Peroxisomal multifunctional enzyme type 2; 17-beta-hydroxysteroid dehydrogenase 4; D-bifunctional protein; Multifunctional protein 2", "protein_names_refseq": "peroxisomal multifunctional enzyme type 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103161104)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway. Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx. Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.n12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.n12", "type": "external" }, { "id": "4.2.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.134", "type": "external" } ], "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016853 isomerase activity;GO:0080023 (2E)-enoyl-CoA hydratase activity;GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IFI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LDY5-1", "uniprot_id": [ { "id": "A0A8C2LDY5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LDY5", "type": "external" } ], "mass": 141872.0, "length": 1486, "protein_name": "Collagen alpha-1(II) chain isoform X1", "gene_name": "Col2a1", "organism": "Hamster", "refseq_name": "collagen alpha-1(II) chain isoform X1", "refseq_ac": [ { "id": "XP_003512954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512954", "type": "external" } ], "gene_names_uniprotkb": "Col2a1", "gene_names_refseq": "Col2a1", "protein_names_uniprotkb": "Collagen alpha-1(II) chain isoform X1", "protein_names_refseq": "collagen alpha-1(II) chain isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755037)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615647.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030020 extracellular matrix structural constituent conferring tensile strength;GO:0042803 protein homodimerization activity;GO:0043394 proteoglycan binding;GO:0048407 platelet-derived growth factor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0005737 cytoplasm;GO:0005604 basement membrane;GO:0005592 collagen type XI trimer", "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0007417 central nervous system development;GO:0007601 visual perception;GO:0030199 collagen fibril organization;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LDY5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IG55-1", "uniprot_id": [ { "id": "A0A061IG55_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IG55", "type": "external" } ], "mass": 83523.0, "length": 741, "protein_name": "ATP-binding cassette sub-family D member 2 isoform X1", "gene_name": "Abcd2", "organism": "Hamster", "refseq_name": "ATP-binding cassette sub-family D member 2 isoform X1", "refseq_ac": [ { "id": "XP_027252130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252130", "type": "external" } ], "gene_names_uniprotkb": "Abcd2", "gene_names_refseq": "Abcd2", "protein_names_uniprotkb": "ATP-binding cassette sub-family D member 2 isoform X1", "protein_names_refseq": "ATP-binding cassette sub-family D member 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758232)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0047617 fatty acyl-CoA hydrolase activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:1903427 negative regulation of reactive oxygen species biosynthetic process;GO:0006635 fatty acid beta-oxidation;GO:0032000 positive regulation of fatty acid beta-oxidation;GO:0042760 very long-chain fatty acid catabolic process;GO:1990535 neuron projection maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IG55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IGQ3-1", "uniprot_id": [ { "id": "A0A061IGQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IGQ3", "type": "external" } ], "mass": 29705.0, "length": 261, "protein_name": "Syntaxin-7", "gene_name": "Stx7", "organism": "Hamster", "refseq_name": "syntaxin-7", "refseq_ac": [ { "id": "XP_027258719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258719", "type": "external" } ], "gene_names_uniprotkb": "Stx7", "gene_names_refseq": "Stx7", "protein_names_uniprotkb": "Syntaxin-7", "protein_names_refseq": "syntaxin-7", "tax_id": 10029, "disease": "", "pathway": " (cge:100758402)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019869 chloride channel inhibitor activity;GO:0019905 syntaxin binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome;GO:0031901 early endosome membrane;GO:0070820 tertiary granule;GO:0005770 late endosome", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0001916 positive regulation of T cell mediated cytotoxicity;GO:1903076 regulation of protein localization to plasma membrane;GO:1902685 positive regulation of receptor localization to synapse;GO:0006906 vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IGQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IGU1-1", "uniprot_id": [ { "id": "A0A061IGU1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IGU1", "type": "external" } ], "mass": 57723.0, "length": 515, "protein_name": "DNA-(apurinic or apyrimidinic site) endonuclease", "gene_name": "LOC100772896", "organism": "Hamster", "refseq_name": "DNA-(apurinic or apyrimidinic site) endonuclease 2", "refseq_ac": [ { "id": "XP_027242498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242498", "type": "external" } ], "gene_names_uniprotkb": "LOC100772896", "gene_names_refseq": "LOC100772896", "protein_names_uniprotkb": "DNA-(apurinic or apyrimidinic site) endonuclease; 3.1.-.-", "protein_names_refseq": "DNA-(apurinic or apyrimidinic site) endonuclease 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772896)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008081 phosphoric diester hydrolase activity;GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006310 DNA recombination;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IGU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LI09-1", "uniprot_id": [ { "id": "A0A8C2LI09_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LI09", "type": "external" } ], "mass": 83985.0, "length": 743, "protein_name": "Kinesin-like protein", "gene_name": "Kif2a", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF2A isoform X11", "refseq_ac": [ { "id": "XP_027257321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257321", "type": "external" } ], "gene_names_uniprotkb": "Kif2a", "gene_names_refseq": "Kif2a", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF2A isoform X11", "tax_id": 10029, "disease": "", "pathway": " (cge:100756108)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0000922 spindle pole;GO:0005654 nucleoplasm", "go_biological_process": "GO:0051301 cell division;GO:0007018 microtubule-based movement;GO:0007019 microtubule depolymerization;GO:0090307 mitotic spindle assembly;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LI09-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IH46-1", "uniprot_id": [ { "id": "A0A061IH46_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IH46", "type": "external" } ], "mass": 77185.0, "length": 679, "protein_name": "Dihydroxyacetone phosphate acyltransferase", "gene_name": "Gnpat", "organism": "Hamster", "refseq_name": "dihydroxyacetone phosphate acyltransferase isoform X1", "refseq_ac": [ { "id": "XP_003496858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496858", "type": "external" } ], "gene_names_uniprotkb": "Gnpat", "gene_names_refseq": "Gnpat", "protein_names_uniprotkb": "Dihydroxyacetone phosphate acyltransferase; 2.3.1.42; DAP-AT; DHAP-AT", "protein_names_refseq": "dihydroxyacetone phosphate acyltransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765024)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613636.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dihydroxyacetonephosphate acyltransferase catalyzing the first step in the biosynthesis of plasmalogens, a subset of phospholipids that differ from other glycerolipids by having an alkyl chain attached through a vinyl ether linkage at the sn-1 position of the glycerol backbone, and which unique physical properties have an impact on various aspects of cell signaling and membrane biology., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.42", "type": "external" } ], "go_molecular_function": "GO:0016287 glycerone-phosphate O-acyltransferase activity;GO:0004366 glycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0006631 fatty acid metabolic process;GO:0008611 ether lipid biosynthetic process;GO:0019432 triglyceride biosynthetic process;GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IH46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IHA3-1", "uniprot_id": [ { "id": "A0A061IHA3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IHA3", "type": "external" } ], "mass": 29994.0, "length": 261, "protein_name": "Calbindin", "gene_name": "Calb1", "organism": "Hamster", "refseq_name": "calbindin isoform X1", "refseq_ac": [ { "id": "XP_003505442", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505442", "type": "external" } ], "gene_names_uniprotkb": "Calb1", "gene_names_refseq": "Calb1", "protein_names_uniprotkb": "Calbindin; Calbindin D28; D-28K; Spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type", "protein_names_refseq": "calbindin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751076)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614147.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005499 vitamin D binding;GO:0099567 calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:0099534 calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007614 short-term memory;GO:0010842 retina layer formation;GO:0007616 long-term memory;GO:0072205 metanephric collecting duct development;GO:1900271 regulation of long-term synaptic potentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IHA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IHC0-1", "uniprot_id": [ { "id": "A0A061IHC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IHC0", "type": "external" } ], "mass": 84925.0, "length": 767, "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "Bard1", "organism": "Hamster", "refseq_name": "BRCA1-associated RING domain protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027252955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252955", "type": "external" } ], "gene_names_uniprotkb": "Bard1", "gene_names_refseq": "Bard1", "protein_names_uniprotkb": "BRCA1-associated RING domain protein 1; 2.3.2.27; RING-type E3 ubiquitin transferase BARD1", "protein_names_refseq": "BRCA1-associated RING domain protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750589)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0070531 BRCA1-A complex;GO:0031436 BRCA1-BARD1 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0043065 positive regulation of apoptotic process;GO:0043066 negative regulation of apoptotic process;GO:0071479 cellular response to ionizing radiation;GO:0046826 negative regulation of protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IHC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IHJ4-1", "uniprot_id": [ { "id": "A0A061IHJ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IHJ4", "type": "external" } ], "mass": 71937.0, "length": 656, "protein_name": "Anion exchange transporter", "gene_name": "Slc26a7", "organism": "Hamster", "refseq_name": "anion exchange transporter", "refseq_ac": [ { "id": "XP_035295859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295859", "type": "external" } ], "gene_names_uniprotkb": "Slc26a7", "gene_names_refseq": "Slc26a7", "protein_names_uniprotkb": "Anion exchange transporter; Solute carrier family 26 member 7", "protein_names_refseq": "anion exchange transporter", "tax_id": 10029, "disease": "", "pathway": " (cge:100767475)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005254 chloride channel activity;GO:0019531 oxalate transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:0140900 chloride:bicarbonate antiporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0055038 recycling endosome membrane;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0001696 gastric acid secretion;GO:0015705 iodide transport;GO:0006590 thyroid hormone generation;GO:0015706 nitrate transmembrane transport;GO:0035429 gluconate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IHJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IHM8-1", "uniprot_id": [ { "id": "A0A061IHM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IHM8", "type": "external" } ], "mass": 217065.0, "length": 2036, "protein_name": "Agrin", "gene_name": "Agrn", "organism": "Hamster", "refseq_name": "agrin isoform X6", "refseq_ac": [ { "id": "XP_027254430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254430", "type": "external" } ], "gene_names_uniprotkb": "Agrn", "gene_names_refseq": "Agrn", "protein_names_uniprotkb": "Agrin", "protein_names_refseq": "agrin isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100765949)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Depending on alternative splicing and post-translational modifications, it has a role in different processes, including neuromuscular junction formation and maintenance, and regulation of neurite outgrowth. Also involved in positive regulation of cartilage formation through alpha-dystroglycan binding and up-regulation of SOX9., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; This released fragment is important for agrin signaling and to exert a maximal dendritic filopodia-inducing effect. All 'z' splice variants (z+) of this fragment also show an increase in the number of filopodia., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0043236 laminin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0045202 synapse;GO:0005604 basement membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0007528 neuromuscular junction development;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IHM8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061II78-1", "uniprot_id": [ { "id": "A0A061II78_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061II78", "type": "external" } ], "mass": 22754.0, "length": 209, "protein_name": "Frataxin, mitochondrial", "gene_name": "Fxn", "organism": "Hamster", "refseq_name": "frataxin, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027262301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262301", "type": "external" } ], "gene_names_uniprotkb": "Fxn", "gene_names_refseq": "Fxn", "protein_names_uniprotkb": "Frataxin, mitochondrial; 1.16.3.1", "protein_names_refseq": "frataxin, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755339)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Modulates the RNA-binding activity of ACO1. May be involved in the cytoplasmic iron-sulfur protein biogenesis. May contribute to oxidative stress resistance and overall cell survival., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "1.16.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.4", "type": "external" } ], "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0008198 ferrous iron binding;GO:0004322 ferroxidase activity;GO:0034986 iron chaperone activity", "go_cellular_component": "GO:0099128 mitochondrial [2Fe-2S] assembly complex", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0070301 cellular response to hydrogen peroxide;GO:0007005 mitochondrion organization;GO:0016540 protein autoprocessing;GO:0090201 negative regulation of release of cytochrome c from mitochondria", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061II78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IIA1-1", "uniprot_id": [ { "id": "A0A061IIA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IIA1", "type": "external" } ], "mass": 138447.0, "length": 1253, "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "gene_name": "Inppl1", "organism": "Hamster", "refseq_name": "phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X3", "refseq_ac": [ { "id": "XP_027263646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263646", "type": "external" } ], "gene_names_uniprotkb": "Inppl1", "gene_names_refseq": "Inppl1", "protein_names_uniprotkb": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; 3.1.3.86; Inositol polyphosphate phosphatase-like protein 1; Protein 51C; SH2 domain-containing inositol 5'-phosphatase 2", "protein_names_refseq": "phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100772102)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0017124 SH3 domain binding;GO:0004445 inositol-polyphosphate 5-phosphatase activity;GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0030027 lamellipodium;GO:0030175 filopodium", "go_biological_process": "GO:0050776 regulation of immune response;GO:0046856 phosphatidylinositol dephosphorylation;GO:0002376 immune system process;GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IIA1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IJ91-1", "uniprot_id": [ { "id": "A0A061IJ91_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IJ91", "type": "external" } ], "mass": 30010.0, "length": 269, "protein_name": "Cathepsin G", "gene_name": "LOC100767270", "organism": "Hamster", "refseq_name": "cathepsin G", "refseq_ac": [ { "id": "XP_003502127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502127", "type": "external" } ], "gene_names_uniprotkb": "LOC100767270", "gene_names_refseq": "LOC100767270", "protein_names_uniprotkb": "Cathepsin G", "protein_names_refseq": "cathepsin G", "tax_id": 10029, "disease": "", "pathway": " (cge:100767270)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008201 heparin binding;GO:0048018 receptor ligand activity;GO:0089720 caspase binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030141 secretory granule", "go_biological_process": "GO:0016485 protein processing;GO:0019731 antibacterial humoral response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0071222 cellular response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IJ91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IJW6-1", "uniprot_id": [ { "id": "A0A061IJW6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IJW6", "type": "external" } ], "mass": 77905.0, "length": 682, "protein_name": "Serine/threonine-protein kinase PLK", "gene_name": "Plk2", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase PLK2", "refseq_ac": [ { "id": "XP_027257291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257291", "type": "external" } ], "gene_names_uniprotkb": "Plk2", "gene_names_refseq": "Plk2", "protein_names_uniprotkb": "Serine/threonine-protein kinase PLK; 2.7.11.21; Polo-like kinase", "protein_names_refseq": "serine/threonine-protein kinase PLK2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753472)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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"type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0043008 ATP-dependent protein binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0030425 dendrite", "go_biological_process": "GO:0007613 memory;GO:0048167 regulation of synaptic plasticity;GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis;GO:2000773 negative regulation of cellular senescence;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IJW6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IK94-1", "uniprot_id": [ { "id": "A0A061IK94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IK94", "type": "external" } ], "mass": 93275.0, "length": 851, "protein_name": "ATP-dependent 6-phosphofructokinase", "gene_name": "Pfkm", "organism": "Hamster", "refseq_name": "ATP-dependent 6-phosphofructokinase, muscle type isoform X1", "refseq_ac": [ { "id": "XP_027252233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252233", "type": "external" } ], "gene_names_uniprotkb": "Pfkm", "gene_names_refseq": "Pfkm", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase; 2.7.1.11; ATP-PFK; Phosphofructokinase; Phosphohexokinase", "protein_names_refseq": "ATP-dependent 6-phosphofructokinase, muscle type isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754270)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" } ], "go_molecular_function": "GO:0070095 fructose-6-phosphate binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0016208 AMP binding", "go_cellular_component": "GO:0016020 membrane;GO:0005945 6-phosphofructokinase complex", "go_biological_process": "GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IK94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IL75-1", "uniprot_id": [ { "id": "A0A061IL75_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IL75", "type": "external" } ], "mass": 74412.0, "length": 662, "protein_name": "DCC-interacting protein 13-beta", "gene_name": "Appl2", "organism": "Hamster", "refseq_name": "DCC-interacting protein 13-beta isoform X1", "refseq_ac": [ { "id": "XP_003508625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508625", "type": "external" } ], "gene_names_uniprotkb": "Appl2", "gene_names_refseq": "Appl2", "protein_names_uniprotkb": "DCC-interacting protein 13-beta; Adapter protein containing PH domain, PTB domain and leucine zipper motif 2", "protein_names_refseq": "DCC-interacting protein 13-beta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771802)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614555.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0044877 protein-containing complex binding;GO:0001786 phosphatidylserine binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005634 nucleus;GO:0031901 early endosome membrane;GO:0032587 ruffle membrane;GO:0044354 macropinosome;GO:0036186 early phagosome membrane", "go_biological_process": "GO:0010762 regulation of fibroblast migration;GO:0046322 negative regulation of fatty acid oxidation;GO:0051289 protein homotetramerization;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IL75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061ILB4-1", "uniprot_id": [ { "id": "A0A061ILB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061ILB4", "type": "external" } ], "mass": 39651.0, "length": 374, "protein_name": "S-(hydroxymethyl)glutathione dehydrogenase", "gene_name": "Adh5", "organism": "Hamster", "refseq_name": "alcohol dehydrogenase class-3", "refseq_ac": [ { "id": "XP_007605859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007605859", "type": "external" } ], "gene_names_uniprotkb": "Adh5", "gene_names_refseq": "Adh5", "protein_names_uniprotkb": "S-(hydroxymethyl)glutathione dehydrogenase; 1.1.1.284", "protein_names_refseq": "alcohol dehydrogenase class-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767929)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003618256.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage. Also acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.284", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.284", "type": "external" }, { "id": "1.1.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.1", "type": "external" }, { "id": "1.1.1.105", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.105", "type": "external" }, { "id": "1.1.1.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.66", "type": "external" } ], "go_molecular_function": "GO:0004022 alcohol dehydrogenase (NAD+) activity;GO:0005504 fatty acid binding;GO:0008270 zinc ion binding;GO:0018467 formaldehyde dehydrogenase (NAD+) activity;GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046294 formaldehyde catabolic process;GO:0051775 response to redox state;GO:0010430 fatty acid omega-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061ILB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IML4-1", "uniprot_id": [ { "id": "A0A061IML4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IML4", "type": "external" } ], "mass": 69016.0, "length": 628, "protein_name": "Complex I assembly factor ACAD9, mitochondrial", "gene_name": "Acad9", "organism": "Hamster", "refseq_name": "complex I assembly factor ACAD9, mitochondrial", "refseq_ac": [ { "id": "XP_027247787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247787", "type": "external" } ], "gene_names_uniprotkb": "Acad9", "gene_names_refseq": "Acad9", "protein_names_uniprotkb": "Complex I assembly factor ACAD9, mitochondrial; 1.3.8.7; 1.3.8.8; Acyl-CoA dehydrogenase family member 9", "protein_names_refseq": "complex I assembly factor ACAD9, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100770943)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.7", "type": "external" }, { "id": "1.3.8.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.8", "type": "external" }, { "id": "1.3.8.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.9", "type": "external" } ], "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0046395 carboxylic acid catabolic process;GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IML4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IRA2-1", "uniprot_id": [ { "id": "A0A061IRA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IRA2", "type": "external" } ], "mass": 112272.0, "length": 981, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp15", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 15 isoform X1", "refseq_ac": [ { "id": "XP_007639707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639707", "type": "external" } ], "gene_names_uniprotkb": "Usp15", "gene_names_refseq": "Usp15", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 15 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759035)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 100 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613811.1) and transcript sequence (JI873397.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0061649 ubiquitin-modified histone reader activity;GO:0005160 transforming growth factor beta receptor binding;GO:0046332 SMAD binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016604 nuclear body", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0051252 regulation of RNA metabolic process;GO:1905035 negative regulation of antifungal innate immune response;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IRA2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IPT3-1", "uniprot_id": [ { "id": "A0A061IPT3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IPT3", "type": "external" } ], "mass": 66602.0, "length": 611, "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "Slc5a8", "organism": "Hamster", "refseq_name": "sodium-coupled monocarboxylate transporter 1", "refseq_ac": [ { "id": "XP_027248381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248381", "type": "external" } ], "gene_names_uniprotkb": "Slc5a8", "gene_names_refseq": "Slc5a8", "protein_names_uniprotkb": "Sodium-coupled monocarboxylate transporter 1; Electrogenic sodium monocarboxylate cotransporter; Solute carrier family 5 member 8", "protein_names_refseq": "sodium-coupled monocarboxylate transporter 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773217)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005343 organic acid:sodium symporter activity", "go_cellular_component": "GO:0070062 extracellular exosome;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0015730 propanoate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IPT3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IQB7-1", "uniprot_id": [ { "id": "A0A061IQB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IQB7", "type": "external" } ], "mass": 56033.0, "length": 508, "protein_name": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "gene_name": "LOC100760414", "organism": "Hamster", "refseq_name": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "refseq_ac": [ { "id": "XP_003507561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507561", "type": "external" } ], "gene_names_uniprotkb": "LOC100760414", "gene_names_refseq": "LOC100760414", "protein_names_uniprotkb": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "protein_names_refseq": "25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100760414)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614393.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004498 calcidiol 1-monooxygenase activity;GO:0062185 secalciferol 1-monooxygenase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0042369 vitamin D catabolic process;GO:0008203 cholesterol metabolic process;GO:0008285 negative regulation of cell population proliferation;GO:0032496 response to lipopolysaccharide;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IQB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A061IR64-1", "uniprot_id": [ { "id": "A0A061IR64_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A061IR64", "type": "external" } ], "mass": 22870.0, "length": 203, "protein_name": "DNA damage-inducible transcript 3 protein", "gene_name": "Ddit3", "organism": "Hamster", "refseq_name": "DNA damage-inducible transcript 3 protein isoform X1", "refseq_ac": [ { "id": "XP_035306970", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306970", "type": "external" } ], "gene_names_uniprotkb": "Ddit3", "gene_names_refseq": "Ddit3", "protein_names_uniprotkb": "DNA damage-inducible transcript 3 protein; C/EBP zeta; C/EBP-homologous protein 10; C/EBP-homologous protein; CCAAT/enhancer-binding protein homologous protein; DDIT-3; Growth arrest and DNA-damage-inducible protein GADD153", "protein_names_refseq": "DNA damage-inducible transcript 3 protein isoform X1", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0036488 CHOP-C/EBP complex;GO:0005737 cytoplasm;GO:1990622 CHOP-ATF3 complex;GO:1990617 CHOP-ATF4 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0016055 Wnt signaling pathway;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0006983 ER overload response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A061IR64-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KX95-1", "uniprot_id": [ { "id": "A0A098KX95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KX95", "type": "external" } ], "mass": 31817.0, "length": 284, "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "gene_name": "Agpat1", "organism": "Hamster", "refseq_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "refseq_ac": [ { "id": "XP_003508512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508512", "type": "external" } ], "gene_names_uniprotkb": "Agpat1", "gene_names_refseq": "Agpat1", "protein_names_uniprotkb": "1-acyl-sn-glycerol-3-phosphate acyltransferase; 2.3.1.51", "protein_names_refseq": "1-acyl-sn-glycerol-3-phosphate acyltransferase alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100758206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 286 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614548.1) and transcript sequence (IACG01092654.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0001819 positive regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A098KX95-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXA7-1", "uniprot_id": [ { "id": "A0A098KXA7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXA7", "type": "external" } ], "mass": 42417.0, "length": 404, "protein_name": "Advanced glycosylation end product-specific receptor", "gene_name": "Ager", "organism": "Hamster", "refseq_name": "advanced glycosylation end product-specific receptor isoform X1", "refseq_ac": [ { "id": "XP_003508510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508510", "type": "external" } ], "gene_names_uniprotkb": "Ager", "gene_names_refseq": "Ager", "protein_names_uniprotkb": "Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products", "protein_names_refseq": "advanced glycosylation end product-specific receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757624)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003508510.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0044548 S100 protein binding;GO:0005055 laminin receptor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005634 nucleus;GO:0005769 early endosome;GO:0009986 cell surface", "go_biological_process": "GO:1900744 regulation of p38MAPK cascade;GO:0006281 DNA repair;GO:0006954 inflammatory response;GO:0007166 cell surface receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A098KXA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXE1-1", "uniprot_id": [ { "id": "A0A098KXE1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXE1", "type": "external" } ], "mass": 56296.0, "length": 519, "protein_name": "Cytosol aminopeptidase", "gene_name": "Lap3", "organism": "Hamster", "refseq_name": "cytosol aminopeptidase", "refseq_ac": [ { "id": "XP_003506025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506025", "type": "external" } ], "gene_names_uniprotkb": "Lap3", "gene_names_refseq": "Lap3", "protein_names_uniprotkb": "Cytosol aminopeptidase; 3.4.11.1; 3.4.11.5; 3.4.13.23; Cysteinylglycine-S-conjugate dipeptidase; Leucine aminopeptidase 3; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase", "protein_names_refseq": "cytosol aminopeptidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100768932)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614204.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.1", "type": "external" }, { "id": "3.4.11.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.5", "type": "external" }, { "id": "3.4.13.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.23", "type": "external" }, { "id": "3.4.13.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.18", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A098KXE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A098KXG8-1", "uniprot_id": [ { "id": "A0A098KXG8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A098KXG8", "type": "external" } ], "mass": 182075.0, "length": 1612, "protein_name": "DNA topoisomerase 2", "gene_name": "Top2b", "organism": "Hamster", "refseq_name": "DNA topoisomerase 2-beta isoform X2", "refseq_ac": [ { "id": "XP_027245183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245183", "type": "external" } ], "gene_names_uniprotkb": "Top2b", "gene_names_refseq": "Top2b", "protein_names_uniprotkb": "DNA topoisomerase 2; 5.6.2.2", "protein_names_refseq": "DNA topoisomerase 2-beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770041)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000792 heterochromatin", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0030183 B cell differentiation;GO:0006265 DNA topological change;GO:0000819 sister chromatid segregation;GO:0045870 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A098KXG8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7GL93-1", "uniprot_id": [ { "id": "A0A3L7GL93_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7GL93", "type": "external" } ], "mass": 63769.0, "length": 565, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgke", "organism": "Hamster", "refseq_name": "diacylglycerol kinase epsilon", "refseq_ac": [ { "id": "XP_007622288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007622288", "type": "external" } ], "gene_names_uniprotkb": "Dgke", "gene_names_refseq": "Dgke", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase epsilon", "tax_id": 10029, "disease": "", "pathway": " (cge:100765113)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613683.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle. Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7GL93-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7GMB9-1", "uniprot_id": [ { "id": "A0A3L7GMB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7GMB9", "type": "external" } ], "mass": 13918.0, "length": 117, "protein_name": "Gamma-aminobutyric acid receptor-associated protein", "gene_name": "Gabarap", "organism": "Hamster", "refseq_name": "gamma-aminobutyric acid receptor-associated protein", "refseq_ac": [ { "id": "XP_003497241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497241", "type": "external" } ], "gene_names_uniprotkb": "Gabarap", "gene_names_refseq": "Gabarap", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor-associated protein", "protein_names_refseq": "gamma-aminobutyric acid receptor-associated protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100767236)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0031625 ubiquitin protein ligase binding;GO:0008429 phosphatidylethanolamine binding;GO:0048487 beta-tubulin binding;GO:0050811 GABA receptor binding", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0000421 autophagosome membrane;GO:0005790 smooth endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005874 microtubule", "go_biological_process": "GO:0006914 autophagy;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035020 regulation of Rac protein signal transduction;GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors;GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7GMB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7GMF6-1", "uniprot_id": [ { "id": "A0A3L7GMF6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7GMF6", "type": "external" } ], "mass": 90931.0, "length": 836, "protein_name": "Neuroligin-2 isoform X2", "gene_name": "Nlgn2", "organism": "Hamster", "refseq_name": "neuroligin-2 isoform X2", "refseq_ac": [ { "id": "XP_027282799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282799", "type": "external" } ], "gene_names_uniprotkb": "Nlgn2", "gene_names_refseq": "Nlgn2", "protein_names_uniprotkb": "Neuroligin-2 isoform X2", "protein_names_refseq": "neuroligin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759673)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0050839 cell adhesion molecule binding;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0009986 cell surface;GO:0030424 axon;GO:0030425 dendrite;GO:0098691 dopaminergic synapse", "go_biological_process": "GO:0097116 gephyrin clustering involved in postsynaptic density assembly;GO:0097104 postsynaptic membrane assembly;GO:0007155 cell adhesion;GO:0032024 positive regulation of insulin secretion;GO:0050885 neuromuscular process controlling balance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7GMF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7GMT8-1", "uniprot_id": [ { "id": "A0A3L7GMT8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7GMT8", "type": "external" } ], "mass": 44925.0, "length": 399, "protein_name": "P2X purinoceptor", "gene_name": "P2rx1", "organism": "Hamster", "refseq_name": "P2X purinoceptor 1 isoform X2", "refseq_ac": [ { "id": "XP_027282612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282612", "type": "external" } ], "gene_names_uniprotkb": "P2rx1", "gene_names_refseq": "P2rx1", "protein_names_uniprotkb": "P2X purinoceptor; P2X purinoceptor 1", "protein_names_refseq": "P2X purinoceptor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756069)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability. Furthermore, CTP functions as a weak affinity agonist for P2RX1., [UniProtKB, UniProtKB]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0001614 purinergic nucleotide receptor activity;GO:0004931 extracellularly ATP-gated monoatomic cation channel activity;GO:0099604 ligand-gated calcium channel activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0045211 postsynaptic membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0033198 response to ATP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7GMT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7GQL3-1", "uniprot_id": [ { "id": "A0A3L7GQL3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7GQL3", "type": "external" } ], "mass": 50100.0, "length": 463, "protein_name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "gene_name": "Sucla2", "organism": "Hamster", "refseq_name": "succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_007647229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647229", "type": "external" } ], "gene_names_uniprotkb": "Sucla2; SUCLA2", "gene_names_refseq": "Sucla2", "protein_names_uniprotkb": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; 6.2.1.5; A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; SCS-betaA; Succinyl-CoA synthetase beta-A chain", "protein_names_refseq": "succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761589)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 556 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614537.1) and transcript sequence (JI892146.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit., [UniProtKB, HAMAP]; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Also able to act as a GTP-specific itaconyl- and malyl-CoA synthetase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.5", "type": "external" }, { "id": "6.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.4", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity;GO:0004776 succinate-CoA ligase (GDP-forming) activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0009361 succinate-CoA ligase complex (ADP-forming)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process;GO:0006108 malate metabolic process;GO:0110052 toxic metabolite repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7GQL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H1M2-1", "uniprot_id": [ { "id": "A0A3L7H1M2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H1M2", "type": "external" } ], "mass": 29353.0, "length": 260, "protein_name": "CD40 ligand", "gene_name": "Cd40lg", "organism": "Hamster", "refseq_name": "CD40 ligand", "refseq_ac": [ { "id": "XP_003499863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499863", "type": "external" } ], "gene_names_uniprotkb": "Cd40lg", "gene_names_refseq": "Cd40lg", "protein_names_uniprotkb": "CD40 ligand; CD40-L; Tumor necrosis factor ligand superfamily member 5", "protein_names_refseq": "CD40 ligand", "tax_id": 10029, "disease": "", "pathway": " (cge:100763089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613755.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling., [UniProtKB, UniProtKB]; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0005125 cytokine activity;GO:0043539 protein serine/threonine kinase activator activity;GO:0005174 CD40 receptor binding;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0023035 CD40 signaling pathway;GO:0006954 inflammatory response;GO:0007229 integrin-mediated signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:0030168 platelet activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H1M2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H2Y7-1", "uniprot_id": [ { "id": "A0A3L7H2Y7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H2Y7", "type": "external" } ], "mass": 52255.0, "length": 474, "protein_name": "Nuclear receptor subfamily 0 group B member 1", "gene_name": "Nr0b1", "organism": "Hamster", "refseq_name": "nuclear receptor subfamily 0 group B member 1", "refseq_ac": [ { "id": "XP_027288610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288610", "type": "external" } ], "gene_names_uniprotkb": "Nr0b1", "gene_names_refseq": "Nr0b1", "protein_names_uniprotkb": "Nuclear receptor subfamily 0 group B member 1; Nuclear receptor DAX-1", "protein_names_refseq": "nuclear receptor subfamily 0 group B member 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754328)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032448 DNA hairpin binding;GO:0003723 RNA binding;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0016607 nuclear speck;GO:0005840 ribosome;GO:0034451 centriolar satellite", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0008584 male gonad development;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H2Y7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H4C7-1", "uniprot_id": [ { "id": "A0A3L7H4C7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H4C7", "type": "external" } ], "mass": 37806.0, "length": 345, "protein_name": "Ephrin-B1", "gene_name": "Efnb1", "organism": "Hamster", "refseq_name": "ephrin-B1 isoform X2", "refseq_ac": [ { "id": "XP_027287577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287577", "type": "external" } ], "gene_names_uniprotkb": "Efnb1", "gene_names_refseq": "Efnb1", "protein_names_uniprotkb": "Ephrin-B1; EFL-3; ELK ligand; EPH-related receptor tyrosine kinase ligand 2", "protein_names_refseq": "ephrin-B1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755216)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells. Shows high affinity for the receptor tyrosine kinase EPHB1/ELK. Can also bind EPHB2 and EPHB3. Binds to, and induces the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft", "go_biological_process": "GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H4C7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H6A3-1", "uniprot_id": [ { "id": "A0A3L7H6A3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H6A3", "type": "external" } ], "mass": 59104.0, "length": 515, "protein_name": "Fatty acyl-CoA reductase", "gene_name": "LOC100758702", "organism": "Hamster", "refseq_name": "fatty acyl-CoA reductase 2 isoform X3", "refseq_ac": [ { "id": "XP_035304391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304391", "type": "external" } ], "gene_names_uniprotkb": "LOC100758702", "gene_names_refseq": "LOC100758702", "protein_names_uniprotkb": "Fatty acyl-CoA reductase; 1.2.1.84", "protein_names_refseq": "fatty acyl-CoA reductase 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100758702)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.84", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.84", "type": "external" } ], "go_molecular_function": "GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity;GO:0102965 alcohol-forming long-chain fatty acyl-CoA reductase activity", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0035336 long-chain fatty-acyl-CoA metabolic process;GO:0010025 wax biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H6A3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H7L1-1", "uniprot_id": [ { "id": "A0A3L7H7L1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H7L1", "type": "external" } ], "mass": 147568.0, "length": 1321, "protein_name": "Lysine-specific demethylase", "gene_name": "Kdm3a", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 3A isoform X1", "refseq_ac": [ { "id": "XP_003503964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503964", "type": "external" } ], "gene_names_uniprotkb": "Kdm3a", "gene_names_refseq": "Kdm3a", "protein_names_uniprotkb": "Lysine-specific demethylase; 1.14.11.65", "protein_names_refseq": "lysine-specific demethylase 3A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771108)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614012.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" }, { "id": "1.14.99.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0008270 zinc ion binding;GO:0031490 chromatin DNA binding;GO:0050681 nuclear androgen receptor binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0046293 formaldehyde biosynthetic process;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0030521 androgen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H7L1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H8K8-1", "uniprot_id": [ { "id": "A0A3L7H8K8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H8K8", "type": "external" } ], "mass": 66707.0, "length": 602, "protein_name": "Potassium voltage-gated channel subfamily A member 5", "gene_name": "Kcna5", "organism": "Hamster", "refseq_name": "potassium voltage-gated channel subfamily A member 5", "refseq_ac": [ { "id": "XP_027284132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284132", "type": "external" } ], "gene_names_uniprotkb": "Kcna5", "gene_names_refseq": "Kcna5", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel subunit Kv1.5", "protein_names_refseq": "potassium voltage-gated channel subfamily A member 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100774436)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0015271 outward rectifier potassium channel activity;GO:0019901 protein kinase binding;GO:0051393 alpha-actinin binding", "go_cellular_component": "GO:0009986 cell surface;GO:0045121 membrane raft;GO:0014704 intercalated disc;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential;GO:0051260 protein homooligomerization;GO:0086091 regulation of heart rate by cardiac conduction;GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization;GO:0060081 membrane hyperpolarization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H8K8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H8L8-1", "uniprot_id": [ { "id": "A0A3L7H8L8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H8L8", "type": "external" } ], "mass": 20451.0, "length": 184, "protein_name": "GTP-binding protein Rheb", "gene_name": "Rheb", "organism": "Hamster", "refseq_name": "GTP-binding protein Rheb isoform X2", "refseq_ac": [ { "id": "XP_027284221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284221", "type": "external" } ], "gene_names_uniprotkb": "Rheb", "gene_names_refseq": "Rheb", "protein_names_uniprotkb": "GTP-binding protein Rheb; Ras homolog enriched in brain", "protein_names_refseq": "GTP-binding protein Rheb isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768233)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Small GTPase that acts as an allosteric activator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. In response to nutrients, growth factors or amino acids, specifically activates the protein kinase activity of MTOR, the catalytic component of the mTORC1 complex: acts by causing a conformational change that allows the alignment of residues in the active site of MTOR, thereby enhancing the phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1). RHEB is also required for localization of the TSC-TBC complex to lysosomal membranes. In response to starvation, RHEB is inactivated by the TSC-TBC complex, preventing activation of mTORC1. Has low intrinsic GTPase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0014069 postsynaptic density;GO:0005681 spliceosomal complex;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007165 signal transduction;GO:0031669 cellular response to nutrient levels;GO:2000074 regulation of type B pancreatic cell development;GO:0120163 negative regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H8L8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7H9U2-1", "uniprot_id": [ { "id": "A0A3L7H9U2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7H9U2", "type": "external" } ], "mass": 39645.0, "length": 355, "protein_name": "Protein Wnt", "gene_name": "LOC100774849", "organism": "Hamster", "refseq_name": "proto-oncogene Wnt-3 isoform X2", "refseq_ac": [ { "id": "XP_027283718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283718", "type": "external" } ], "gene_names_uniprotkb": "LOC100774849", "gene_names_refseq": "LOC100774849", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "proto-oncogene Wnt-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774849)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0019904 protein domain specific binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0000902 cell morphogenesis;GO:0060070 canonical Wnt signaling pathway;GO:0045669 positive regulation of osteoblast differentiation;GO:0050767 regulation of neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7H9U2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HAL2-1", "uniprot_id": [ { "id": "A0A3L7HAL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HAL2", "type": "external" } ], "mass": 34543.0, "length": 321, "protein_name": "Glycerol-3-phosphate phosphatase", "gene_name": "Pgp", "organism": "Hamster", "refseq_name": "glycerol-3-phosphate phosphatase isoform X1", "refseq_ac": [ { "id": "XP_016830648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830648", "type": "external" } ], "gene_names_uniprotkb": "Pgp", "gene_names_refseq": "Pgp", "protein_names_uniprotkb": "Glycerol-3-phosphate phosphatase; 3.1.3.21; 3.1.3.48; Aspartate-based ubiquitous Mg(2+)-dependent phosphatase; Phosphoglycolate phosphatase", "protein_names_refseq": "glycerol-3-phosphate phosphatase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770052)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 192 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) and transcript sequence (IACG01001380.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016830648.1. COMPLETENESS: full length., [RefSeq]; Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, also has a phosphatase activity toward ADP, ATP, GDP and GTP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0008967 phosphoglycolate phosphatase activity;GO:0043262 ADP phosphatase activity;GO:0043136 sn-glycerol 3-phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0006114 glycerol biosynthetic process;GO:0045721 negative regulation of gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HAL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HCU4-1", "uniprot_id": [ { "id": "A0A3L7HCU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HCU4", "type": "external" } ], "mass": 26991.0, "length": 237, "protein_name": "Pro-opiomelanocortin", "gene_name": "Pomc", "organism": "Hamster", "refseq_name": "pro-opiomelanocortin isoform X2", "refseq_ac": [ { "id": "XP_027280198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280198", "type": "external" } ], "gene_names_uniprotkb": "Pomc", "gene_names_refseq": "Pomc", "protein_names_uniprotkb": "Pro-opiomelanocortin; Corticotropin-lipotropin", "protein_names_refseq": "pro-opiomelanocortin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756311)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endogenous opiate., [UniProtKB, UniProtKB]; Endogenous orexigenic opiate., [UniProtKB, UniProtKB]; Precursor protein of pituitary hormones that are involved in diverse physiological processes, including the regulation of energy balance, stress response, immune function and skin pigmentation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0031781 type 3 melanocortin receptor binding;GO:0031782 type 4 melanocortin receptor binding;GO:0070996 type 1 melanocortin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0006091 generation of precursor metabolites and energy;GO:0007218 neuropeptide signaling pathway;GO:0007267 cell-cell signaling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032098 regulation of appetite", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HCU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HDQ8-1", "uniprot_id": [ { "id": "A0A3L7HDQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HDQ8", "type": "external" } ], "mass": 55075.0, "length": 495, "protein_name": "Growth/differentiation factor 5", "gene_name": "LOC100762027", "organism": "Hamster", "refseq_name": "growth/differentiation factor 5 isoform X2", "refseq_ac": [ { "id": "XP_027277158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277158", "type": "external" } ], "gene_names_uniprotkb": "LOC100762027", "gene_names_refseq": "LOC100762027", "protein_names_uniprotkb": "Growth/differentiation factor 5; Bone morphogenetic protein 14", "protein_names_refseq": "growth/differentiation factor 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762027)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0036122 BMP binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0050680 negative regulation of epithelial cell proliferation;GO:0030509 BMP signaling pathway;GO:0030513 positive regulation of BMP signaling pathway;GO:0032332 positive regulation of chondrocyte differentiation;GO:0032331 negative regulation of chondrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HDQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HG65-1", "uniprot_id": [ { "id": "A0A3L7HG65_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HG65", "type": "external" } ], "mass": 226070.0, "length": 2166, "protein_name": "SH3 and multiple ankyrin repeat domains protein 1", "gene_name": "Shank1", "organism": "Hamster", "refseq_name": "SH3 and multiple ankyrin repeat domains protein 1 isoform X2", "refseq_ac": [ { "id": "XP_035302511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302511", "type": "external" } ], "gene_names_uniprotkb": "Shank1", "gene_names_refseq": "Shank1", "protein_names_uniprotkb": "SH3 and multiple ankyrin repeat domains protein 1", "protein_names_refseq": "SH3 and multiple ankyrin repeat domains protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757633)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 12, "predicted_n_glycosites": 0, "predicted_o_glycosites": 12, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035255 ionotropic glutamate receptor binding;GO:0098919 structural constituent of postsynaptic density;GO:0030160 synaptic receptor adaptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0042048 olfactory behavior;GO:0046959 habituation;GO:0050894 determination of affect;GO:0008306 associative learning;GO:0030534 adult behavior", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HG65-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HHR6-1", "uniprot_id": [ { "id": "A0A3L7HHR6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HHR6", "type": "external" } ], "mass": 34024.0, "length": 313, "protein_name": "E3 ubiquitin-protein ligase RNF126", "gene_name": "Rnf126", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF126 isoform X2", "refseq_ac": [ { "id": "XP_027275254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275254", "type": "external" } ], "gene_names_uniprotkb": "Rnf126", "gene_names_refseq": "Rnf126", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF126; 2.3.2.27; RING finger protein 126", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF126 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103160352)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005154 epidermal growth factor receptor binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0042147 retrograde transport, endosome to Golgi;GO:0070936 protein K48-linked ubiquitination;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway;GO:0070534 protein K63-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HHR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HHY4-1", "uniprot_id": [ { "id": "A0A3L7HHY4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HHY4", "type": "external" } ], "mass": 28474.0, "length": 265, "protein_name": "Neutrophil elastase", "gene_name": "Elane", "organism": "Hamster", "refseq_name": "neutrophil elastase", "refseq_ac": [ { "id": "XP_003502652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502652", "type": "external" } ], "gene_names_uniprotkb": "Elane", "gene_names_refseq": "Elane", "protein_names_uniprotkb": "Neutrophil elastase", "protein_names_refseq": "neutrophil elastase", "tax_id": 10029, "disease": "", "pathway": " (cge:100752732)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613904.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0004252 serine-type endopeptidase activity;GO:0008201 heparin binding;GO:0003714 transcription corepressor activity;GO:0019955 cytokine binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0009986 cell surface;GO:0017053 transcription repressor complex;GO:0042582 azurophil granule", "go_biological_process": "GO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria;GO:0070945 neutrophil-mediated killing of gram-negative bacterium;GO:0070947 neutrophil-mediated killing of fungus;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HHY4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HKL8-1", "uniprot_id": [ { "id": "A0A3L7HKL8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HKL8", "type": "external" } ], "mass": 53892.0, "length": 492, "protein_name": "Extracellular tyrosine-protein kinase PKDCC", "gene_name": "Pkdcc", "organism": "Hamster", "refseq_name": "extracellular tyrosine-protein kinase PKDCC isoform X2", "refseq_ac": [ { "id": "XP_027273711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273711", "type": "external" } ], "gene_names_uniprotkb": "Pkdcc", "gene_names_refseq": "Pkdcc", "protein_names_uniprotkb": "Extracellular tyrosine-protein kinase PKDCC; 2.7.10.2; Protein kinase domain-containing protein, cytoplasmic; Protein kinase-like protein SgK493; Sugen kinase 493; Vertebrate lonesome kinase", "protein_names_refseq": "extracellular tyrosine-protein kinase PKDCC isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764428)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0015031 protein transport;GO:0030154 cell differentiation;GO:0048286 lung alveolus development;GO:0001501 skeletal system development;GO:0048566 embryonic digestive tract development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HKL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HKN4-1", "uniprot_id": [ { "id": "A0A3L7HKN4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HKN4", "type": "external" } ], "mass": 38004.0, "length": 323, "protein_name": "Sphingolipid delta(4)-desaturase DES1", "gene_name": "Degs1", "organism": "Hamster", "refseq_name": "sphingolipid delta(4)-desaturase DES1 isoform X2", "refseq_ac": [ { "id": "XP_027274600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274600", "type": "external" } ], "gene_names_uniprotkb": "Degs1", "gene_names_refseq": "Degs1", "protein_names_uniprotkb": "Sphingolipid delta(4)-desaturase DES1; 1.14.19.17; Degenerative spermatocyte homolog 1; Dihydroceramide desaturase-1; Retinol isomerase", "protein_names_refseq": "sphingolipid delta(4)-desaturase DES1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753569)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0042284 sphingolipid delta-4 desaturase activity;GO:0050251 retinol isomerase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HKN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HLS8-1", "uniprot_id": [ { "id": "A0A3L7HLS8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HLS8", "type": "external" } ], "mass": 49420.0, "length": 434, "protein_name": "Protein maelstrom homolog", "gene_name": "Mael", "organism": "Hamster", "refseq_name": "protein maelstrom homolog isoform X1", "refseq_ac": [ { "id": "XP_003502336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502336", "type": "external" } ], "gene_names_uniprotkb": "Mael", "gene_names_refseq": "Mael", "protein_names_uniprotkb": "Protein maelstrom homolog", "protein_names_refseq": "protein maelstrom homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768422)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613889.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0000785 chromatin;GO:0001741 XY body;GO:0033391 chromatoid body", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0060964 regulation of miRNA-mediated gene silencing;GO:0045892 negative regulation of DNA-templated transcription;GO:0007140 male meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HLS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HLU5-1", "uniprot_id": [ { "id": "A0A3L7HLU5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HLU5", "type": "external" } ], "mass": 45195.0, "length": 402, "protein_name": "Plasminogen activator inhibitor 1", "gene_name": "Serpine1", "organism": "Hamster", "refseq_name": "plasminogen activator inhibitor 1 isoform X1", "refseq_ac": [ { "id": "XP_007639866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639866", "type": "external" } ], "gene_names_uniprotkb": "Serpine1", "gene_names_refseq": "Serpine1", "protein_names_uniprotkb": "Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1", "protein_names_refseq": "plasminogen activator inhibitor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759702)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 423 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613822.1) and transcript sequences (IACG01069806.1 and JI878505.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0070062 extracellular exosome", "go_biological_process": "GO:0097187 dentinogenesis;GO:1901331 positive regulation of odontoblast differentiation;GO:0035491 positive regulation of leukotriene production involved in inflammatory response;GO:0061044 negative regulation of vascular wound healing;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HLU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LDZ8-1", "uniprot_id": [ { "id": "A0A8C2LDZ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LDZ8", "type": "external" } ], "mass": 138026.0, "length": 1277, "protein_name": "Calmodulin-regulated spectrin-associated protein 3 isoform X2", "gene_name": "Camsap3", "organism": "Hamster", "refseq_name": "calmodulin-regulated spectrin-associated protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027271586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271586", "type": "external" } ], "gene_names_uniprotkb": "Camsap3", "gene_names_refseq": "Camsap3", "protein_names_uniprotkb": "Calmodulin-regulated spectrin-associated protein 3 isoform X2", "protein_names_refseq": "calmodulin-regulated spectrin-associated protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772080)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0030507 spectrin binding;GO:0051011 microtubule minus-end binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0036449 microtubule minus-end;GO:0005813 centrosome;GO:0031514 motile cilium;GO:0005930 axoneme;GO:0036064 ciliary basal body", "go_biological_process": "GO:0031175 neuron projection development;GO:0007026 negative regulation of microtubule depolymerization;GO:0031122 cytoplasmic microtubule organization;GO:0051893 regulation of focal adhesion assembly;GO:0009792 embryo development ending in birth or egg hatching", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LDZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HMF6-1", "uniprot_id": [ { "id": "A0A3L7HMF6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HMF6", "type": "external" } ], "mass": 51822.0, "length": 458, "protein_name": "Protein adenylyltransferase FICD", "gene_name": "Ficd", "organism": "Hamster", "refseq_name": "protein adenylyltransferase FICD", "refseq_ac": [ { "id": "XP_003507373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507373", "type": "external" } ], "gene_names_uniprotkb": "Ficd", "gene_names_refseq": "Ficd", "protein_names_uniprotkb": "Protein adenylyltransferase FICD; 2.7.7.108; AMPylator FICD; De-AMPylase FICD; FIC domain-containing protein", "protein_names_refseq": "protein adenylyltransferase FICD", "tax_id": 10029, "disease": "", "pathway": " (cge:100760999)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614356.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context. The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place. Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP. In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of HSPA5/BiP at 'Thr-518', thereby inactivating it. In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from HSPA5/BiP at 'Thr-518', leading to restore HSPA5/BiP activity. Although it is able to AMPylate RhoA, Rac and Cdc42 Rho GTPases in vitro, Rho GTPases do not constitute physiological substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "2.7.7.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.108", "type": "external" } ], "go_molecular_function": "GO:0044603 protein adenylylhydrolase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0030544 Hsp70 protein binding;GO:0070733 AMPylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:1903894 regulation of IRE1-mediated unfolded protein response;GO:0034976 response to endoplasmic reticulum stress;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HMF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HNF2-1", "uniprot_id": [ { "id": "A0A3L7HNF2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HNF2", "type": "external" } ], "mass": 53665.0, "length": 480, "protein_name": "Stromelysin-1", "gene_name": "Mmp3", "organism": "Hamster", "refseq_name": "stromelysin-1 isoform X2", "refseq_ac": [ { "id": "XP_027270982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270982", "type": "external" } ], "gene_names_uniprotkb": "Mmp3", "gene_names_refseq": "Mmp3", "protein_names_uniprotkb": "Stromelysin-1; 3.4.24.17; Matrix metalloproteinase-3", "protein_names_refseq": "stromelysin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754565)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0045087 innate immune response;GO:0031334 positive regulation of protein-containing complex assembly;GO:2000378 negative regulation of reactive oxygen species metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HNF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HPH2-1", "uniprot_id": [ { "id": "A0A3L7HPH2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HPH2", "type": "external" } ], "mass": 22733.0, "length": 201, "protein_name": "Transmembrane emp24 domain-containing protein 2 isoform X2", "gene_name": "Tmed2", "organism": "Hamster", "refseq_name": "transmembrane emp24 domain-containing protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027269705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269705", "type": "external" } ], "gene_names_uniprotkb": "Tmed2", "gene_names_refseq": "Tmed2", "protein_names_uniprotkb": "Transmembrane emp24 domain-containing protein 2 isoform X2", "protein_names_refseq": "transmembrane emp24 domain-containing protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689307)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0005119 smoothened binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0072659 protein localization to plasma membrane;GO:0048598 embryonic morphogenesis;GO:0001893 maternal placenta development;GO:0060716 labyrinthine layer blood vessel development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HPH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HQ14-1", "uniprot_id": [ { "id": "A0A3L7HQ14_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HQ14", "type": "external" } ], "mass": 91377.0, "length": 801, "protein_name": "Eukaryotic translation initiation factor 3 subunit B", "gene_name": "Eif3b", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 3 subunit B isoform X2", "refseq_ac": [ { "id": "XP_027269310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269310", "type": "external" } ], "gene_names_uniprotkb": "Eif3b; EIF3B; EIF3S9", "gene_names_refseq": "Eif3b", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit B; Eukaryotic translation initiation factor 3 subunit 9; eIF-3-eta; eIF3b", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762979)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome., [UniProtKB, UniProtKB]; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0045202 synapse;GO:0010494 cytoplasmic stress granule;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex", "go_biological_process": "GO:0075522 IRES-dependent viral translational initiation;GO:0006446 regulation of translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0075525 viral translational termination-reinitiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HQ14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HQC4-1", "uniprot_id": [ { "id": "A0A3L7HQC4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HQC4", "type": "external" } ], "mass": 41682.0, "length": 378, "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase", "gene_name": "Lfng", "organism": "Hamster", "refseq_name": "beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "refseq_ac": [ { "id": "XP_027269314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269314", "type": "external" } ], "gene_names_uniprotkb": "Lfng", "gene_names_refseq": "Lfng", "protein_names_uniprotkb": "Beta-1,3-N-acetylglucosaminyltransferase; 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "protein_names_refseq": "beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "tax_id": 10029, "disease": "", "pathway": " (cge:100762397)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.222", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.222", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0007389 pattern specification process;GO:0014807 regulation of somitogenesis;GO:0030217 T cell differentiation;GO:0002315 marginal zone B cell differentiation;GO:1902367 negative regulation of Notch signaling pathway involved in somitogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HQC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HQF4-1", "uniprot_id": [ { "id": "A0A3L7HQF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HQF4", "type": "external" } ], "mass": 70016.0, "length": 624, "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "gene_name": "Eif2ak1", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_007647184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647184", "type": "external" } ], "gene_names_uniprotkb": "Eif2ak1", "gene_names_refseq": "Eif2ak1", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 2-alpha kinase 1; 2.7.11.1; Heme-controlled repressor; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; Heme-regulated inhibitor; Hemin-sensitive initiation factor 2-alpha kinase", "protein_names_refseq": "eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764727)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 232 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613618.1) and transcript sequence (IACG01069496.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007647184.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005828 kinetochore microtubule;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0010824 regulation of centrosome duplication;GO:0031468 nuclear membrane reassembly;GO:0039702 viral budding via host ESCRT complex;GO:0071985 multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HQJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HRA2-1", "uniprot_id": [ { "id": "A0A3L7HRA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HRA2", "type": "external" } ], "mass": 21660.0, "length": 195, "protein_name": "U8 snoRNA-decapping enzyme", "gene_name": "Nudt16", "organism": "Hamster", "refseq_name": "U8 snoRNA-decapping enzyme isoform X2", "refseq_ac": [ { "id": "XP_027270563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270563", "type": "external" } ], "gene_names_uniprotkb": "Nudt16", "gene_names_refseq": "Nudt16", "protein_names_uniprotkb": "U8 snoRNA-decapping enzyme; 3.6.1.62; 3.6.1.64; IDP phosphatase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; m7GpppN-mRNA hydrolase", "protein_names_refseq": "U8 snoRNA-decapping enzyme isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768978)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003614046.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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"protein_name": "Zinc finger protein ZPR1", "gene_name": "Zpr1", "organism": "Hamster", "refseq_name": "zinc finger protein ZPR1 isoform X1", "refseq_ac": [ { "id": "XP_003511140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511140", "type": "external" } ], "gene_names_uniprotkb": "Zpr1", "gene_names_refseq": "Zpr1", "protein_names_uniprotkb": "Zinc finger protein ZPR1; Zinc finger protein 259", "protein_names_refseq": "zinc finger protein ZPR1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773173)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615029.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030971 receptor tyrosine kinase binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030426 growth cone;GO:0043204 perikaryon;GO:0048471 perinuclear region of cytoplasm;GO:0015030 Cajal body", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0033120 positive regulation of RNA splicing;GO:0006397 mRNA processing;GO:0021510 spinal cord development;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HSE5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HU27-1", "uniprot_id": [ { "id": "A0A3L7HU27_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HU27", "type": "external" } ], "mass": 55428.0, "length": 509, "protein_name": "Sperm-associated antigen 6", "gene_name": "LOC100758363", "organism": "Hamster", "refseq_name": "sperm-associated antigen 6", "refseq_ac": [ { "id": "XP_003502891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502891", "type": "external" } ], "gene_names_uniprotkb": "LOC100758363", "gene_names_refseq": "LOC100758363", "protein_names_uniprotkb": "Sperm-associated antigen 6; Protein PF16 homolog", "protein_names_refseq": "sperm-associated antigen 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100758363)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613919.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005874 microtubule;GO:0001669 acrosomal vesicle;GO:0005930 axoneme;GO:0097228 sperm principal piece", "go_biological_process": "GO:0003351 epithelial cilium movement involved in extracellular fluid movement;GO:0046847 filopodium assembly;GO:1990138 neuron projection extension;GO:0007288 sperm axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HU27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HUR6-1", "uniprot_id": [ { "id": "A0A3L7HUR6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HUR6", "type": "external" } ], "mass": 52052.0, "length": 465, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "Smad5", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 5", "refseq_ac": [ { "id": "XP_003503786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503786", "type": "external" } ], "gene_names_uniprotkb": "Smad5", "gene_names_refseq": "Smad5", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100754116)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 135 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613997.1) and transcript sequence (IACG01061161.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0017151 DEAD/H-box RNA helicase binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0043066 negative regulation of apoptotic process;GO:0048863 stem cell differentiation;GO:0006879 intracellular iron ion homeostasis;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HUR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HV18-1", "uniprot_id": [ { "id": "A0A3L7HV18_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HV18", "type": "external" } ], "mass": 16568.0, "length": 161, "protein_name": "DNA-binding protein inhibitor ID-4", "gene_name": "LOC113835065", "organism": "Hamster", "refseq_name": "DNA-binding protein inhibitor ID-4", "refseq_ac": [ { "id": "XP_027265786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265786", "type": "external" } ], "gene_names_uniprotkb": "LOC113835065", "gene_names_refseq": "LOC113835065", "protein_names_uniprotkb": "DNA-binding protein inhibitor ID-4; Inhibitor of DNA binding 4; Inhibitor of differentiation 4", "protein_names_refseq": "DNA-binding protein inhibitor ID-4", "tax_id": 10029, "disease": "", "pathway": " (cge:113835065)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140416 transcription regulator inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HV18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HVH9-1", "uniprot_id": [ { "id": "A0A3L7HVH9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HVH9", "type": "external" } ], "mass": 37405.0, "length": 333, "protein_name": "Pro-cathepsin H", "gene_name": "Ctsh", "organism": "Hamster", "refseq_name": "pro-cathepsin H", "refseq_ac": [ { "id": "XP_003495667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495667", "type": "external" } ], "gene_names_uniprotkb": "Ctsh", "gene_names_refseq": "Ctsh", "protein_names_uniprotkb": "Pro-cathepsin H", "protein_names_refseq": "pro-cathepsin H", "tax_id": 10029, "disease": "", "pathway": " (cge:100756691)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Important for the overall degradation of proteins in lysosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0070324 thyroid hormone binding;GO:0004177 aminopeptidase activity;GO:0004197 cysteine-type endopeptidase activity;GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005764 lysosome;GO:0097208 alveolar lamellar body", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0043129 surfactant homeostasis;GO:0032526 response to retinoic acid;GO:0070371 ERK1 and ERK2 cascade;GO:0010634 positive regulation of epithelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HVH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HVU2-1", "uniprot_id": [ { "id": "A0A3L7HVU2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HVU2", "type": "external" } ], "mass": 43048.0, "length": 397, "protein_name": "Potassium channel subfamily K member 4", "gene_name": "Kcnk4", "organism": "Hamster", "refseq_name": "potassium channel subfamily K member 4", "refseq_ac": [ { "id": "XP_003511330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511330", "type": "external" } ], "gene_names_uniprotkb": "Kcnk4", "gene_names_refseq": "Kcnk4", "protein_names_uniprotkb": "Potassium channel subfamily K member 4; TWIK-related arachidonic acid-stimulated potassium channel protein", "protein_names_refseq": "potassium channel subfamily K member 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100760723)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615068.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015271 outward rectifier potassium channel activity;GO:0022841 potassium ion leak channel activity;GO:0098782 mechanosensitive potassium channel activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0034705 potassium channel complex;GO:0005886 plasma membrane;GO:0030424 axon", "go_biological_process": "GO:0030322 stabilization of membrane potential;GO:0050976 detection of mechanical stimulus involved in sensory perception of touch;GO:0071260 cellular response to mechanical stimulus;GO:0071468 cellular response to acidic pH;GO:1990478 response to ultrasound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HVU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HWT4-1", "uniprot_id": [ { "id": "A0A3L7HWT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HWT4", "type": "external" } ], "mass": 57632.0, "length": 501, "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "LOC100772751", "organism": "Hamster", "refseq_name": "vitamin D 25-hydroxylase", "refseq_ac": [ { "id": "XP_027265936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265936", "type": "external" } ], "gene_names_uniprotkb": "LOC100772751", "gene_names_refseq": "LOC100772751", "protein_names_uniprotkb": "Vitamin D 25-hydroxylase; 1.14.14.24; Cytochrome P450 2R1", "protein_names_refseq": "vitamin D 25-hydroxylase", "tax_id": 10029, "disease": "", "pathway": " (cge:100772751)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A cytochrome P450 monooxygenase involved in activation of vitamin D precursors. Catalyzes hydroxylation at C-25 of both forms of vitamin D, vitamin D(2) and D(3) (calciol). Can metabolize vitamin D analogs/prodrugs 1alpha-hydroxyvitamin D(2) (doxercalciferol) and 1alpha-hydroxyvitamin D(3) (alfacalcidol) forming 25-hydroxy derivatives. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.24", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0042803 protein homodimerization activity;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0030343 vitamin D3 25-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HWT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HX57-1", "uniprot_id": [ { "id": "A0A3L7HX57_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HX57", "type": "external" } ], "mass": 36931.0, "length": 339, "protein_name": "Fructose-1,6-bisphosphatase isozyme 2", "gene_name": "LOC100761248", "organism": "Hamster", "refseq_name": "fructose-1,6-bisphosphatase isozyme 2", "refseq_ac": [ { "id": "XP_003515427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515427", "type": "external" } ], "gene_names_uniprotkb": "LOC100761248", "gene_names_refseq": "LOC100761248", "protein_names_uniprotkb": "Fructose-1,6-bisphosphatase isozyme 2; 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; Muscle FBPase", "protein_names_refseq": "fructose-1,6-bisphosphatase isozyme 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761248)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617909.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.11", "type": "external" } ], "go_molecular_function": "GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030018 Z disc;GO:0070161 anchoring junction", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006000 fructose metabolic process;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0006002 fructose 6-phosphate metabolic process;GO:0005986 sucrose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HX57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HYI9-1", "uniprot_id": [ { "id": "A0A3L7HYI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HYI9", "type": "external" } ], "mass": 67197.0, "length": 612, "protein_name": "E3 ubiquitin-protein ligase synoviolin", "gene_name": "Syvn1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase synoviolin", "refseq_ac": [ { "id": "XP_003514634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514634", "type": "external" } ], "gene_names_uniprotkb": "Syvn1", "gene_names_refseq": "Syvn1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase synoviolin; 2.3.2.27; RING-type E3 ubiquitin transferase synoviolin; Synovial apoptosis inhibitor 1", "protein_names_refseq": "E3 ubiquitin-protein ligase synoviolin", "tax_id": 10029, "disease": "", "pathway": " (cge:100765313)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616756.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0051117 ATPase binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005790 smooth endoplasmic reticulum;GO:0005886 plasma membrane;GO:0036513 Derlin-1 retrotranslocation complex;GO:0044322 endoplasmic reticulum quality control compartment", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050821 protein stabilization;GO:0070936 protein K48-linked ubiquitination;GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HYI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7HYQ7-1", "uniprot_id": [ { "id": "A0A3L7HYQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7HYQ7", "type": "external" } ], "mass": 31500.0, "length": 290, "protein_name": "Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6", "gene_name": "Plpp6", "organism": "Hamster", "refseq_name": "phospholipid phosphatase 6 isoform X1", "refseq_ac": [ { "id": "XP_016832986", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832986", "type": "external" } ], "gene_names_uniprotkb": "Plpp6", "gene_names_refseq": "Plpp6", "protein_names_uniprotkb": "Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6; 3.6.1.68; Phospholipid phosphatase 6", "protein_names_refseq": "phospholipid phosphatase 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103162885)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 292 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614228.1) and transcript sequence (IACG01087907.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016832986.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.6.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.76", "type": "external" }, { "id": "3.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4", "type": "external" }, { "id": "3.1.3.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106", "type": "external" }, { "id": "3.6.1.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75", "type": "external" }, { "id": "3.6.1.58", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.58", "type": "external" } ], "go_molecular_function": "GO:0052642 lysophosphatidic acid phosphatase activity;GO:0008195 phosphatidate phosphatase activity;GO:0042392 sphingosine-1-phosphate phosphatase activity;GO:0106405 isoprenoid diphosphate phosphatase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0042632 cholesterol homeostasis;GO:0046839 phospholipid dephosphorylation;GO:1902565 positive regulation of neutrophil activation;GO:0033383 geranyl diphosphate metabolic process;GO:0045339 farnesyl diphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7HYQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I0T0-1", "uniprot_id": [ { "id": "A0A3L7I0T0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I0T0", "type": "external" } ], "mass": 83463.0, "length": 733, "protein_name": "Transcriptional repressor CTCF", "gene_name": "Ctcf", "organism": "Hamster", "refseq_name": "transcriptional repressor CTCF isoform X2", "refseq_ac": [ { "id": "XP_007647370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647370", "type": "external" } ], "gene_names_uniprotkb": "Ctcf", "gene_names_refseq": "Ctcf", "protein_names_uniprotkb": "Transcriptional repressor CTCF; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog", "protein_names_refseq": "transcriptional repressor CTCF isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043035 chromatin insulator sequence binding;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001221 transcription coregulator binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000775 chromosome, centromeric region;GO:0000793 condensed chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0071459 protein localization to chromosome, centromeric region;GO:0006351 DNA-templated transcription;GO:0007059 chromosome segregation;GO:0008285 negative regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I0T0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I1R2-1", "uniprot_id": [ { "id": "A0A3L7I1R2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I1R2", "type": "external" } ], "mass": 58679.0, "length": 519, "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "Riok3", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase RIO3 isoform X1", "refseq_ac": [ { "id": "XP_027260134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260134", "type": "external" } ], "gene_names_uniprotkb": "Riok3", "gene_names_refseq": "Riok3", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIO3; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase RIO3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754135)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase involved in a ribosome quality control that takes place when ribosomes have stalled, leading to 18S non-functional rRNA decay and degradation of the 40S ribosomal subunit. Acts downstream of RNF10: specifically recognizes and binds RPS2/us5 and RPS3/us3 monoubiquitinated by RNF10, promoting degradation of the 40S ribosomal subunit in a kinase-dependent manner. The RNF10-RIOK3 ribosome quality control takes place in response to ribosome subunit imbalance or downstream the EIF2AK4/GCN2-mediated integrated stress response (ISR). Also involved in regulation of type I interferon (IFN)-dependent immune response, possibly by acting as an adapter protein essential for the recruitment of TBK1 to IRF3. Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling. Can inhibit CASP10 isoform 7-mediated activation of the NF-kappa-B signaling pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0140036 ubiquitin-modified protein reader activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0089720 caspase binding", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0030688 preribosome, small subunit precursor;GO:0005737 cytoplasm", "go_biological_process": "GO:0071359 cellular response to dsRNA;GO:0070651 nonfunctional rRNA decay;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0043124 negative regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I1R2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I1S9-1", "uniprot_id": [ { "id": "A0A3L7I1S9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I1S9", "type": "external" } ], "mass": 9010.0, "length": 80, "protein_name": "Nuclear protein 1", "gene_name": "Nupr1", "organism": "Hamster", "refseq_name": "nuclear protein 1", "refseq_ac": [ { "id": "XP_027260457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260457", "type": "external" } ], "gene_names_uniprotkb": "Nupr1", "gene_names_refseq": "Nupr1", "protein_names_uniprotkb": "Nuclear protein 1", "protein_names_refseq": "nuclear protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753781)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0010698 acetyltransferase activator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0032993 protein-DNA complex", "go_biological_process": "GO:1902902 negative regulation of autophagosome assembly;GO:1904036 negative regulation of epithelial cell apoptotic process;GO:1904691 negative regulation of type B pancreatic cell proliferation;GO:0045820 negative regulation of glycolytic process;GO:0045787 positive regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I1S9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I304-1", "uniprot_id": [ { "id": "A0A3L7I304_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I304", "type": "external" } ], "mass": 33170.0, "length": 302, "protein_name": "Syntaxin-17", "gene_name": "Stx17", "organism": "Hamster", "refseq_name": "syntaxin-17 isoform X2", "refseq_ac": [ { "id": "XP_027258925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258925", "type": "external" } ], "gene_names_uniprotkb": "Stx17", "gene_names_refseq": "Stx17", "protein_names_uniprotkb": "Syntaxin-17", "protein_names_refseq": "syntaxin-17 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751748)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding;GO:0019903 protein phosphatase binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0030897 HOPS complex;GO:0000421 autophagosome membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006887 exocytosis;GO:0007030 Golgi organization;GO:0097111 endoplasmic reticulum-Golgi intermediate compartment organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I304-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I3I1-1", "uniprot_id": [ { "id": "A0A3L7I3I1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I3I1", "type": "external" } ], "mass": 31490.0, "length": 292, "protein_name": "Aquaporin-3", "gene_name": "Aqp3", "organism": "Hamster", "refseq_name": "aquaporin-3", "refseq_ac": [ { "id": "XP_003512012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512012", "type": "external" } ], "gene_names_uniprotkb": "Aqp3", "gene_names_refseq": "Aqp3", "protein_names_uniprotkb": "Aquaporin-3; Aquaglyceroporin-3", "protein_names_refseq": "aquaporin-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100758981)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615295.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0015250 water channel activity;GO:0015254 glycerol channel activity;GO:0015204 urea transmembrane transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005911 cell-cell junction;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0032526 response to retinoic acid;GO:0042476 odontogenesis;GO:0002684 positive regulation of immune system process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I3I1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I3N2-1", "uniprot_id": [ { "id": "A0A3L7I3N2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I3N2", "type": "external" } ], "mass": 98213.0, "length": 889, "protein_name": "Cytoplasmic aconitate hydratase", "gene_name": "Aco1", "organism": "Hamster", "refseq_name": "cytoplasmic aconitate hydratase", "refseq_ac": [ { "id": "XP_027259183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259183", "type": "external" } ], "gene_names_uniprotkb": "Aco1", "gene_names_refseq": "Aco1", "protein_names_uniprotkb": "Cytoplasmic aconitate hydratase; 4.2.1.3; Citrate hydro-lyase; Iron regulatory protein 1; Iron-responsive element-binding protein 1", "protein_names_refseq": "cytoplasmic aconitate hydratase", "tax_id": 10029, "disease": "", "pathway": " (cge:100766024)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional iron sensor that switches between 2 activities depending on iron availability. Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration and utilization. Binds to iron-responsive elements (IRES) in the untranslated region of target mRNAs preventing for instance the translation of ferritin and aminolevulinic acid synthase and stabilizing the transferrin receptor mRNA., [UniProtKB, UniProtKB]; Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0030350 iron-responsive element binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0006101 citrate metabolic process;GO:0006879 intracellular iron ion homeostasis;GO:0010040 response to iron(II) ion;GO:0006740 NADPH regeneration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I3N2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I4Q7-1", "uniprot_id": [ { "id": "A0A3L7I4Q7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I4Q7", "type": "external" } ], "mass": 30576.0, "length": 320, "protein_name": "Myristoylated alanine-rich C-kinase substrate", "gene_name": "Marcks", "organism": "Hamster", "refseq_name": "myristoylated alanine-rich C-kinase substrate isoform X2", "refseq_ac": [ { "id": "XP_027257940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257940", "type": "external" } ], "gene_names_uniprotkb": "Marcks", "gene_names_refseq": "Marcks", "protein_names_uniprotkb": "Myristoylated alanine-rich C-kinase substrate", "protein_names_refseq": "myristoylated alanine-rich C-kinase substrate isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113834282)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0005080 protein kinase C binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0032432 actin filament bundle;GO:0042585 germinal vesicle", "go_biological_process": "GO:0006915 apoptotic process;GO:0007417 central nervous system development;GO:0051017 actin filament bundle assembly;GO:0021915 neural tube development;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I4Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I6U4-1", "uniprot_id": [ { "id": "A0A3L7I6U4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I6U4", "type": "external" } ], "mass": 34541.0, "length": 329, "protein_name": "T-cell acute lymphocytic leukemia protein 1", "gene_name": "Tal1", "organism": "Hamster", "refseq_name": "T-cell acute lymphocytic leukemia protein 1", "refseq_ac": [ { "id": "XP_035294828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294828", "type": "external" } ], "gene_names_uniprotkb": "Tal1", "gene_names_refseq": "Tal1", "protein_names_uniprotkb": "T-cell acute lymphocytic leukemia protein 1", "protein_names_refseq": "T-cell acute lymphocytic leukemia protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766563)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0046983 protein dimerization activity;GO:0042826 histone deacetylase binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0030219 megakaryocyte differentiation;GO:0035162 embryonic hemopoiesis;GO:0030221 basophil differentiation;GO:0006351 DNA-templated transcription;GO:0045931 positive regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I6U4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I7S6-1", "uniprot_id": [ { "id": "A0A3L7I7S6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I7S6", "type": "external" } ], "mass": 19738.0, "length": 178, "protein_name": "Endothelin-2", "gene_name": "Edn2", "organism": "Hamster", "refseq_name": "endothelin-2 isoform X2", "refseq_ac": [ { "id": "XP_027254930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254930", "type": "external" } ], "gene_names_uniprotkb": "Edn2", "gene_names_refseq": "Edn2", "protein_names_uniprotkb": "Endothelin-2; Preproendothelin-2", "protein_names_refseq": "endothelin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754793)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0031708 endothelin B receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0086100 endothelin receptor signaling pathway;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0006874 intracellular calcium ion homeostasis;GO:0019229 regulation of vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I7S6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I877-1", "uniprot_id": [ { "id": "A0A3L7I877_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I877", "type": "external" } ], "mass": 72645.0, "length": 664, "protein_name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "gene_name": "Sdha", "organism": "Hamster", "refseq_name": "succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "refseq_ac": [ { "id": "XP_003513683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513683", "type": "external" } ], "gene_names_uniprotkb": "Sdha", "gene_names_refseq": "Sdha", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; 1.3.5.1", "protein_names_refseq": "succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100750732)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616050.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. Can act as a tumor suppressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.5.1", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008177 succinate dehydrogenase (quinone) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0007399 nervous system development;GO:0006105 succinate metabolic process;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I877-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I8I1-1", "uniprot_id": [ { "id": "A0A3L7I8I1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I8I1", "type": "external" } ], "mass": 33894.0, "length": 307, "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "Ldlrap1", "organism": "Hamster", "refseq_name": "low density lipoprotein receptor adapter protein 1 isoform X3", "refseq_ac": [ { "id": "XP_027255459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255459", "type": "external" } ], "gene_names_uniprotkb": "Ldlrap1", "gene_names_refseq": "Ldlrap1", "protein_names_uniprotkb": "Low density lipoprotein receptor adapter protein 1; Autosomal recessive hypercholesterolemia protein homolog", "protein_names_refseq": "low density lipoprotein receptor adapter protein 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytosis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface. Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0001540 amyloid-beta binding;GO:0035612 AP-2 adaptor complex binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0009898 cytoplasmic side of plasma membrane;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0031623 receptor internalization;GO:0042632 cholesterol homeostasis;GO:0042982 amyloid precursor protein metabolic process;GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I8I1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I8N6-1", "uniprot_id": [ { "id": "A0A3L7I8N6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I8N6", "type": "external" } ], "mass": 23355.0, "length": 211, "protein_name": "Phospholipase A2", "gene_name": "Pla2g2f", "organism": "Hamster", "refseq_name": "group IIF secretory phospholipase A2", "refseq_ac": [ { "id": "XP_003506947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506947", "type": "external" } ], "gene_names_uniprotkb": "Pla2g2f", "gene_names_refseq": "Pla2g2f", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "group IIF secretory phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755005)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614302.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0036148 phosphatidylglycerol acyl-chain remodeling;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0036152 phosphatidylethanolamine acyl-chain remodeling;GO:0036151 phosphatidylcholine acyl-chain remodeling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I8N6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I8S0-1", "uniprot_id": [ { "id": "A0A3L7I8S0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I8S0", "type": "external" } ], "mass": 32235.0, "length": 286, "protein_name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "gene_name": "Sdhb", "organism": "Hamster", "refseq_name": "succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027255690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255690", "type": "external" } ], "gene_names_uniprotkb": "Sdhb", "gene_names_refseq": "Sdhb", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; 1.3.5.1", "protein_names_refseq": "succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771246)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)., [UniProtKB, UniProtKB]; Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.5.1", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I8S0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I8Y1-1", "uniprot_id": [ { "id": "A0A3L7I8Y1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I8Y1", "type": "external" } ], "mass": 55881.0, "length": 520, "protein_name": "Protein RCC2", "gene_name": "Rcc2", "organism": "Hamster", "refseq_name": "protein RCC2 isoform X2", "refseq_ac": [ { "id": "XP_027255679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255679", "type": "external" } ], "gene_names_uniprotkb": "Rcc2", "gene_names_refseq": "Rcc2", "protein_names_uniprotkb": "Protein RCC2", "protein_names_refseq": "protein RCC2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771065)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005886 plasma membrane;GO:0031901 early endosome membrane;GO:0030496 midbody;GO:0034506 chromosome, centromeric core domain", "go_biological_process": "GO:1900027 regulation of ruffle assembly;GO:0010762 regulation of fibroblast migration;GO:0007229 integrin-mediated signaling pathway;GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I8Y1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7I9E2-1", "uniprot_id": [ { "id": "A0A3L7I9E2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7I9E2", "type": "external" } ], "mass": 30862.0, "length": 269, "protein_name": "Proenkephalin-A", "gene_name": "Penk", "organism": "Hamster", "refseq_name": "proenkephalin-A isoform X2", "refseq_ac": [ { "id": "XP_035294902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294902", "type": "external" } ], "gene_names_uniprotkb": "Penk", "gene_names_refseq": "Penk", "protein_names_uniprotkb": "Proenkephalin-A", "protein_names_refseq": "proenkephalin-A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774423)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Increases glutamate release in the striatum and decreases GABA concentration in the striatum., [UniProtKB, UniProtKB]; Met-enkephalin-Arg-Phe neuropeptide acts as a strong ligand of Mu-type opioid receptor OPRM1. Met-enkephalin-Arg-Phe-binding to OPRM1 in the nucleus accumbens of the brain increases activation of OPRM1, leading to long-term synaptic depression of glutamate release., [UniProtKB, UniProtKB]; Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress., [UniProtKB, UniProtKB]; Neuropeptide that induces itch in a histamine-independent manner as well as nociceptive sensations. Acts as a ligand for MRGPRX1 receptor in sensory neurons of dorsal root ganglion: MRGPRX1-binding in the peripheral nervous system elicits itch and scratching, while MRGPRX1-binding in the central nervous system dampens chronic pain., [UniProtKB, UniProtKB]; Neuropeptide that mediates stress-induced opioid analgesia. Also possesses non-opioid action by acting as a ligand for MRGPRX1 receptor to induce itch in a histamine-independent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031628 opioid receptor binding;GO:0001515 opioid peptide activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0043025 neuronal cell body;GO:0043679 axon terminus", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007268 chemical synaptic transmission;GO:0019226 transmission of nerve impulse;GO:0038003 G protein-coupled opioid receptor signaling pathway;GO:0160025 sensory perception of itch", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7I9E2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IA59-1", "uniprot_id": [ { "id": "A0A3L7IA59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IA59", "type": "external" } ], "mass": 17404.0, "length": 155, "protein_name": "Multifunctional fusion protein", "gene_name": "Fgf1", "organism": "Hamster", "refseq_name": "fibroblast growth factor 1 isoform X1", "refseq_ac": [ { "id": "XP_035294941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294941", "type": "external" } ], "gene_names_uniprotkb": "Fgf1", "gene_names_refseq": "Fgf1", "protein_names_uniprotkb": "Multifunctional fusion protein; Acidic fibroblast growth factor; Heparin-binding growth factor 1", "protein_names_refseq": "fibroblast growth factor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764257)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0044548 S100 protein binding;GO:0008083 growth factor activity;GO:0005104 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0031012 extracellular matrix", "go_biological_process": "GO:1903672 positive regulation of sprouting angiogenesis;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IA59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IEC2-1", "uniprot_id": [ { "id": "A0A3L7IEC2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IEC2", "type": "external" } ], "mass": 37566.0, "length": 354, "protein_name": "Krueppel-like factor 2", "gene_name": "Klf2", "organism": "Hamster", "refseq_name": "Krueppel-like factor 2 isoform X2", "refseq_ac": [ { "id": "XP_027250693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250693", "type": "external" } ], "gene_names_uniprotkb": "Klf2", "gene_names_refseq": "Klf2", "protein_names_uniprotkb": "Krueppel-like factor 2; Lung krueppel-like factor", "protein_names_refseq": "Krueppel-like factor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113833401)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0097533 cellular stress response to acid chemical;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051247 positive regulation of protein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IEC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IHK6-1", "uniprot_id": [ { "id": "A0A3L7IHK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IHK6", "type": "external" } ], "mass": 47295.0, "length": 421, "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "gene_name": "Pip4k2c", "organism": "Hamster", "refseq_name": "phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X2", "refseq_ac": [ { "id": "XP_027248045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248045", "type": "external" } ], "gene_names_uniprotkb": "Pip4k2c", "gene_names_refseq": "Pip4k2c", "protein_names_uniprotkb": "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; 2.7.1.149; Phosphatidylinositol 5-phosphate 4-kinase type II gamma", "protein_names_refseq": "phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764086)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.149", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.149", "type": "external" } ], "go_molecular_function": "GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005776 autophagosome", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:2000786 positive regulation of autophagosome assembly;GO:0061909 autophagosome-lysosome fusion;GO:1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IHK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IHY9-1", "uniprot_id": [ { "id": "A0A3L7IHY9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IHY9", "type": "external" } ], "mass": 69105.0, "length": 611, "protein_name": "Leukotriene A(4) hydrolase", "gene_name": "Lta4h", "organism": "Hamster", "refseq_name": "leukotriene A-4 hydrolase isoform X1", "refseq_ac": [ { "id": "XP_003501464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501464", "type": "external" } ], "gene_names_uniprotkb": "Lta4h", "gene_names_refseq": "Lta4h", "protein_names_uniprotkb": "Leukotriene A(4) hydrolase; 3.3.2.6; LTA-4 hydrolase", "protein_names_refseq": "leukotriene A-4 hydrolase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753500)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613849.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the pro-inflammatory mediator leukotriene B4 (LTB4), as well as other lipid epoxides. Also has aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides. In addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL). Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.6", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004301 epoxide hydrolase activity;GO:0070006 metalloaminopeptidase activity;GO:0004463 leukotriene-A4 hydrolase activity;GO:0045148 tripeptide aminopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0043171 peptide catabolic process;GO:0019370 leukotriene biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IHY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IIQ8-1", "uniprot_id": [ { "id": "A0A3L7IIQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IIQ8", "type": "external" } ], "mass": 32605.0, "length": 278, "protein_name": "Inhibitor of growth protein", "gene_name": "Ing2", "organism": "Hamster", "refseq_name": "inhibitor of growth protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027246869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246869", "type": "external" } ], "gene_names_uniprotkb": "Ing2", "gene_names_refseq": "Ing2", "protein_names_uniprotkb": "Inhibitor of growth protein", "protein_names_refseq": "inhibitor of growth protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755912)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of an histone acetyltransferase complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding;GO:0035091 phosphatidylinositol binding;GO:0140002 histone H3K4me3 reader activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070822 Sin3-type complex;GO:0016602 CCAAT-binding factor complex", "go_biological_process": "GO:0048133 male germ-line stem cell asymmetric division;GO:0030317 flagellated sperm motility;GO:0007286 spermatid development;GO:0045893 positive regulation of DNA-templated transcription;GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IIQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IIT8-1", "uniprot_id": [ { "id": "A0A3L7IIT8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IIT8", "type": "external" } ], "mass": 26040.0, "length": 238, "protein_name": "Tetraspanin", "gene_name": "Cd63", "organism": "Hamster", "refseq_name": "CD63 antigen isoform X1", "refseq_ac": [ { "id": "XP_003506255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506255", "type": "external" } ], "gene_names_uniprotkb": "Cd63", "gene_names_refseq": "Cd63", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "CD63 antigen isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772167)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614217.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031904 endosome lumen;GO:0070062 extracellular exosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0015031 protein transport;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0035646 endosome to melanosome transport;GO:0002092 positive regulation of receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IIT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IIV4-1", "uniprot_id": [ { "id": "A0A3L7IIV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IIV4", "type": "external" } ], "mass": 32853.0, "length": 298, "protein_name": "ADP/ATP translocase", "gene_name": "Slc25a4", "organism": "Hamster", "refseq_name": "ADP/ATP translocase 1 isoform X2", "refseq_ac": [ { "id": "XP_027246901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246901", "type": "external" } ], "gene_names_uniprotkb": "Slc25a4", "gene_names_refseq": "Slc25a4", "protein_names_uniprotkb": "ADP/ATP translocase; ADP,ATP carrier protein", "protein_names_refseq": "ADP/ATP translocase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751779)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005471 ATP:ADP antiporter activity;GO:0015078 proton transmembrane transporter activity;GO:0017077 oxidative phosphorylation uncoupler activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:1901526 positive regulation of mitophagy;GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0060546 negative regulation of necroptotic process;GO:1990845 adaptive thermogenesis;GO:0140021 mitochondrial ADP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IIV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IKD7-1", "uniprot_id": [ { "id": "A0A3L7IKD7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IKD7", "type": "external" } ], "mass": 35712.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC100756490", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase-like isoform X2", "refseq_ac": [ { "id": "XP_035308808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308808", "type": "external" } ], "gene_names_uniprotkb": "LOC100756490", "gene_names_refseq": "LOC100756490", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756490)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IKD7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IKK7-1", "uniprot_id": [ { "id": "A0A3L7IKK7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IKK7", "type": "external" } ], "mass": 24716.0, "length": 212, "protein_name": "Programmed cell death protein 10", "gene_name": "Pdcd10", "organism": "Hamster", "refseq_name": "programmed cell death protein 10", "refseq_ac": [ { "id": "XP_003505782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505782", "type": "external" } ], "gene_names_uniprotkb": "Pdcd10", "gene_names_refseq": "Pdcd10", "protein_names_uniprotkb": "Programmed cell death protein 10", "protein_names_refseq": "programmed cell death protein 10", "tax_id": 10029, "disease": "", "pathway": " (cge:100759439)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614182.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0090443 FAR/SIN/STRIPAK complex", "go_biological_process": "GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IKK7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7ILT0-1", "uniprot_id": [ { "id": "A0A3L7ILT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7ILT0", "type": "external" } ], "mass": 10847.0, "length": 98, "protein_name": "C-X-C motif chemokine", "gene_name": "Cxcl10", "organism": "Hamster", "refseq_name": "C-X-C motif chemokine 10", "refseq_ac": [ { "id": "XP_003512799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512799", "type": "external" } ], "gene_names_uniprotkb": "Cxcl10", "gene_names_refseq": "Cxcl10", "protein_names_uniprotkb": "C-X-C motif chemokine", "protein_names_refseq": "C-X-C motif chemokine 10", "tax_id": 10029, "disease": "", "pathway": " (cge:100770195)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615570.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0042056 chemoattractant activity;GO:0008009 chemokine activity;GO:0048248 CXCR3 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0070098 chemokine-mediated signaling pathway;GO:0090026 positive regulation of monocyte chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7ILT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IMU8-1", "uniprot_id": [ { "id": "A0A3L7IMU8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IMU8", "type": "external" } ], "mass": 32501.0, "length": 292, "protein_name": "2P domain potassium channel Talk-1", "gene_name": "Kcnk16", "organism": "Hamster", "refseq_name": "potassium channel subfamily K member 16", "refseq_ac": [ { "id": "XP_003509548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509548", "type": "external" } ], "gene_names_uniprotkb": "Kcnk16", "gene_names_refseq": "Kcnk16", "protein_names_uniprotkb": "2P domain potassium channel Talk-1; TWIK-related alkaline pH-activated K(+) channel 1", "protein_names_refseq": "potassium channel subfamily K member 16", "tax_id": 10029, "disease": "", "pathway": " (cge:100760808)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614720.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015271 outward rectifier potassium channel activity;GO:0022841 potassium ion leak channel activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0086011 membrane repolarization during action potential;GO:0030322 stabilization of membrane potential;GO:0098900 regulation of action potential;GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051279 regulation of release of sequestered calcium ion into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IMU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IN18-1", "uniprot_id": [ { "id": "A0A3L7IN18_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IN18", "type": "external" } ], "mass": 50364.0, "length": 441, "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "Pacsin1", "organism": "Hamster", "refseq_name": "protein kinase C and casein kinase substrate in neurons protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027244811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244811", "type": "external" } ], "gene_names_uniprotkb": "Pacsin1", "gene_names_refseq": "Pacsin1", "protein_names_uniprotkb": "Protein kinase C and casein kinase substrate in neurons protein 1", "protein_names_refseq": "protein kinase C and casein kinase substrate in neurons protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759729)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042802 identical protein binding;GO:0008092 cytoskeletal protein binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0030659 cytoplasmic vesicle membrane;GO:0043005 neuron projection;GO:0030137 COPI-coated vesicle", "go_biological_process": "GO:0007015 actin filament organization;GO:0030100 regulation of endocytosis;GO:0048812 neuron projection morphogenesis;GO:0072657 protein localization to membrane;GO:1900006 positive regulation of dendrite development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IN18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A3L7IR17-1", "uniprot_id": [ { "id": "A0A3L7IR17_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A3L7IR17", "type": "external" } ], "mass": 20553.0, "length": 192, "protein_name": "E3 ubiquitin-protein ligase RNF", "gene_name": "Rnf185", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF185 isoform X1", "refseq_ac": [ { "id": "XP_007648065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648065", "type": "external" } ], "gene_names_uniprotkb": "Rnf185", "gene_names_refseq": "Rnf185", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF; 2.3.2.27; RING finger protein", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF185 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761198)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 86 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614682.1) and transcript sequence (IACG01120541.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding;GO:0061630 ubiquitin protein ligase activity;GO:0043130 ubiquitin binding;GO:0044390 ubiquitin-like protein conjugating enzyme binding", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051607 defense response to virus;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0051865 protein autoubiquitination;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3L7IR17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2L606-1", "uniprot_id": [ { "id": "A0A8C2L606_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2L606", "type": "external" } ], "mass": 33241.0, "length": 291, "protein_name": "Lys-63-specific deubiquitinase", "gene_name": "Brcc3", "organism": "Hamster", "refseq_name": "lys-63-specific deubiquitinase BRCC36 isoform X2", "refseq_ac": [ { "id": "XP_027288305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288305", "type": "external" } ], "gene_names_uniprotkb": "Brcc3", "gene_names_refseq": "Brcc3", "protein_names_uniprotkb": "Lys-63-specific deubiquitinase; 3.4.19.-", "protein_names_refseq": "lys-63-specific deubiquitinase BRCC36 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756268)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031593 polyubiquitin modification-dependent protein binding;GO:0046872 metal ion binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0140492 metal-dependent deubiquitinase activity;GO:0008237 metallopeptidase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0070552 BRISC complex;GO:0070531 BRCA1-A complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006508 proteolysis;GO:0051301 cell division;GO:0070536 protein K63-linked deubiquitination;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2L606-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2L745-1", "uniprot_id": [ { "id": "A0A8C2L745_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2L745", "type": "external" } ], "mass": 47796.0, "length": 428, "protein_name": "Growth/differentiation factor 2", "gene_name": "Gdf2", "organism": "Hamster", "refseq_name": "growth/differentiation factor 2", "refseq_ac": [ { "id": "XP_003495365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495365", "type": "external" } ], "gene_names_uniprotkb": "Gdf2", "gene_names_refseq": "Gdf2", "protein_names_uniprotkb": "Growth/differentiation factor 2; Bone morphogenetic protein 9", "protein_names_refseq": "growth/differentiation factor 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772200)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001570 vasculogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006879 intracellular iron ion homeostasis;GO:0045766 positive regulation of angiogenesis;GO:0001937 negative regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2L745-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2L7P1-1", "uniprot_id": [ { "id": "A0A8C2L7P1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2L7P1", "type": "external" } ], "mass": 106537.0, "length": 952, "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "Cyld", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase CYLD isoform X1", "refseq_ac": [ { "id": "XP_016829680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829680", "type": "external" } ], "gene_names_uniprotkb": "Cyld", "gene_names_refseq": "Cyld", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase CYLD; 3.4.19.12; Deubiquitinating enzyme CYLD; Ubiquitin thioesterase CYLD; Ubiquitin-specific-processing protease CYLD", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase CYLD isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758070)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613741.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0045087 innate immune response;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2L7P1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2L7Q1-1", "uniprot_id": [ { "id": "A0A8C2L7Q1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2L7Q1", "type": "external" } ], "mass": 174848.0, "length": 1621, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "Alk", "organism": "Hamster", "refseq_name": "ALK tyrosine kinase receptor isoform X2", "refseq_ac": [ { "id": "XP_027280213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280213", "type": "external" } ], "gene_names_uniprotkb": "Alk", "gene_names_refseq": "Alk", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "ALK tyrosine kinase receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760366)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027280213.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0030298 receptor signaling protein tyrosine kinase activator activity;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0050995 negative regulation of lipid catabolic process;GO:0097009 energy homeostasis;GO:0045664 regulation of neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2L7Q1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2L828-1", "uniprot_id": [ { "id": "A0A8C2L828_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2L828", "type": "external" } ], "mass": 127847.0, "length": 1116, "protein_name": "Transient receptor potential cation channel subfamily A member 1", "gene_name": "Trpa1", "organism": "Hamster", "refseq_name": "transient receptor potential cation channel subfamily A member 1 isoform X1", "refseq_ac": [ { "id": "XP_027254622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254622", "type": "external" } ], "gene_names_uniprotkb": "Trpa1", "gene_names_refseq": "Trpa1", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily A member 1; Ankyrin-like with transmembrane domains protein 1; Wasabi receptor", "protein_names_refseq": "transient receptor potential cation channel subfamily A member 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751384)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0097604 temperature-gated cation channel activity;GO:0042802 identical protein binding;GO:0015278 intracellularly gated calcium channel activity;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032421 stereocilium bundle;GO:1902495 transmembrane transporter complex", "go_biological_process": "GO:0071240 cellular response to food;GO:0007166 cell surface receptor signaling pathway;GO:0009409 response to cold;GO:0051289 protein homotetramerization;GO:0006874 intracellular calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2L828-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LA90-1", "uniprot_id": [ { "id": "A0A8C2LA90_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LA90", "type": "external" } ], "mass": 42961.0, "length": 408, "protein_name": "POU domain protein", "gene_name": "LOC100772680", "organism": "Hamster", "refseq_name": "POU domain, class 4, transcription factor 2 isoform X2", "refseq_ac": [ { "id": "XP_027260722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260722", "type": "external" } ], "gene_names_uniprotkb": "LOC100772680", "gene_names_refseq": "LOC100772680", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 4, transcription factor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772680)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039 p53 binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005667 transcription regulator complex;GO:0000791 euchromatin", "go_biological_process": "GO:1902870 negative regulation of amacrine cell differentiation;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0032869 cellular response to insulin stimulus;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LA90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LAZ5-1", "uniprot_id": [ { "id": "A0A8C2LAZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LAZ5", "type": "external" } ], "mass": 68194.0, "length": 614, "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ache", "organism": "Hamster", "refseq_name": "acetylcholinesterase isoform X2", "refseq_ac": [ { "id": "XP_027272030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272030", "type": "external" } ], "gene_names_uniprotkb": "Ache", "gene_names_refseq": "Ache", "protein_names_uniprotkb": "Carboxylic ester hydrolase; 3.1.1.-", "protein_names_refseq": "acetylcholinesterase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770679)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042166 acetylcholine binding;GO:0042803 protein homodimerization activity;GO:0005518 collagen binding;GO:0043236 laminin binding;GO:0003990 acetylcholinesterase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0019695 choline metabolic process;GO:0007155 cell adhesion;GO:0002076 osteoblast development;GO:0006581 acetylcholine catabolic process;GO:0120162 positive regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LAZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LBB3-1", "uniprot_id": [ { "id": "A0A8C2LBB3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LBB3", "type": "external" } ], "mass": 25005.0, "length": 224, "protein_name": "Peroxiredoxin-6", "gene_name": "Prdx6", "organism": "Hamster", "refseq_name": "peroxiredoxin-6 isoform X1", "refseq_ac": [ { "id": "XP_003497727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497727", "type": "external" } ], "gene_names_uniprotkb": "Prdx6", "gene_names_refseq": "Prdx6", "protein_names_uniprotkb": "Peroxiredoxin-6; 1.11.1.27", "protein_names_refseq": "peroxiredoxin-6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754867)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 98 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613658.1) and transcript sequence (JI875976.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003497727.1. COMPLETENESS: full length., [RefSeq]; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "1.16.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.4", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0004623 phospholipase A2 activity;GO:0051920 peroxiredoxin activity;GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0048026 positive regulation of mRNA splicing, via spliceosome;GO:0006979 response to oxidative stress;GO:0046475 glycerophospholipid catabolic process;GO:0045454 cell redox homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LBB3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LBB7-1", "uniprot_id": [ { "id": "A0A8C2LBB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LBB7", "type": "external" } ], "mass": 47886.0, "length": 425, "protein_name": "Intermediate conductance calcium-activated potassium channel protein 4", "gene_name": "Kcnn4", "organism": "Hamster", "refseq_name": "intermediate conductance calcium-activated potassium channel protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027286946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286946", "type": "external" } ], "gene_names_uniprotkb": "Kcnn4", "gene_names_refseq": "Kcnn4", "protein_names_uniprotkb": "Intermediate conductance calcium-activated potassium channel protein 4; KCa3.1", "protein_names_refseq": "intermediate conductance calcium-activated potassium channel protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768359)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0042803 protein homodimerization activity;GO:0019903 protein phosphatase binding;GO:0016286 small conductance calcium-activated potassium channel activity;GO:0022894 intermediate conductance calcium-activated potassium channel activity", "go_cellular_component": "GO:0031982 vesicle;GO:0032587 ruffle membrane", "go_biological_process": "GO:0030322 stabilization of membrane potential;GO:0051289 protein homotetramerization;GO:0006816 calcium ion transport;GO:0006884 cell volume homeostasis;GO:0050862 positive regulation of T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LBB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LBG1-1", "uniprot_id": [ { "id": "A0A8C2LBG1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LBG1", "type": "external" } ], "mass": 120275.0, "length": 1062, "protein_name": "DNA replication ATP-dependent helicase/nuclease", "gene_name": "Dna2", "organism": "Hamster", "refseq_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "refseq_ac": [ { "id": "XP_035307113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307113", "type": "external" } ], "gene_names_uniprotkb": "Dna2", "gene_names_refseq": "Dna2", "protein_names_uniprotkb": "DNA replication ATP-dependent helicase/nuclease; 3.1.-.-; 3.6.4.12", "protein_names_refseq": "DNA replication ATP-dependent helicase/nuclease DNA2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761842)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 162 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) and transcript sequence (IACG01040145.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042645 mitochondrial nucleoid;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0006284 base-excision repair;GO:0045740 positive regulation of DNA replication;GO:0000729 DNA double-strand break processing;GO:0006264 mitochondrial DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LBG1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LDI0-1", "uniprot_id": [ { "id": "A0A8C2LDI0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LDI0", "type": "external" } ], "mass": 47727.0, "length": 441, "protein_name": "C-terminal-binding protein 1", "gene_name": "Ctbp1", "organism": "Hamster", "refseq_name": "C-terminal-binding protein 1 isoform X4", "refseq_ac": [ { "id": "XP_027243022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243022", "type": "external" } ], "gene_names_uniprotkb": "Ctbp1", "gene_names_refseq": "Ctbp1", "protein_names_uniprotkb": "C-terminal-binding protein 1", "protein_names_refseq": "C-terminal-binding protein 1 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100766703)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003714 transcription corepressor activity;GO:0051287 NAD binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0001221 transcription coregulator binding", "go_cellular_component": "GO:0005634 nucleus;GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0098831 presynaptic active zone cytoplasmic component;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0097091 synaptic vesicle clustering;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0050872 white fat cell differentiation;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LDI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LBK4-1", "uniprot_id": [ { "id": "A0A8C2LBK4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LBK4", "type": "external" } ], "mass": 70802.0, "length": 640, "protein_name": "5-aminolevulinate synthase", "gene_name": "Alas1", "organism": "Hamster", "refseq_name": "5-aminolevulinate synthase, nonspecific, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003497683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497683", "type": "external" } ], "gene_names_uniprotkb": "Alas1", "gene_names_refseq": "Alas1", "protein_names_uniprotkb": "5-aminolevulinate synthase; 2.3.1.37; 5-aminolevulinic acid synthase; Delta-ALA synthase; Delta-aminolevulinate synthase", "protein_names_refseq": "5-aminolevulinate synthase, nonspecific, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766370)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.37", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding;GO:0003870 5-aminolevulinate synthase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0048821 erythrocyte development;GO:0006782 protoporphyrinogen IX biosynthetic process;GO:0042541 hemoglobin biosynthetic process;GO:0006784 heme A biosynthetic process;GO:1903412 response to bile acid", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LBK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LBN5-1", "uniprot_id": [ { "id": "A0A8C2LBN5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LBN5", "type": "external" } ], "mass": 56202.0, "length": 497, "protein_name": "Glycine receptor subunit beta", "gene_name": "Glrb", "organism": "Hamster", "refseq_name": "glycine receptor subunit beta isoform X1", "refseq_ac": [ { "id": "XP_003500261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500261", "type": "external" } ], "gene_names_uniprotkb": "Glrb", "gene_names_refseq": "Glrb", "protein_names_uniprotkb": "Glycine receptor subunit beta; Glycine receptor 58 kDa subunit", "protein_names_refseq": "glycine receptor subunit beta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764841)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613781.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0016934 extracellularly glycine-gated chloride channel activity;GO:0004888 transmembrane signaling receptor activity;GO:0016594 glycine binding;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "go_cellular_component": "GO:0016935 glycine-gated chloride channel complex;GO:0098982 GABA-ergic synapse;GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0001964 startle response;GO:0060012 synaptic transmission, glycinergic;GO:0007218 neuropeptide signaling pathway;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LBN5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LBR7-1", "uniprot_id": [ { "id": "A0A8C2LBR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LBR7", "type": "external" } ], "mass": 38742.0, "length": 349, "protein_name": "Macrophage-capping protein", "gene_name": "Capg", "organism": "Hamster", "refseq_name": "macrophage-capping protein", "refseq_ac": [ { "id": "XP_027285269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285269", "type": "external" } ], "gene_names_uniprotkb": "Capg", "gene_names_refseq": "Capg", "protein_names_uniprotkb": "Macrophage-capping protein; Actin regulatory protein CAP-G", "protein_names_refseq": "macrophage-capping protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100774775)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0019904 protein domain specific binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0042470 melanosome", "go_biological_process": "GO:0007417 central nervous system development;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:0030031 cell projection assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LBR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LCE8-1", "uniprot_id": [ { "id": "A0A8C2LCE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LCE8", "type": "external" } ], "mass": 18071.0, "length": 162, "protein_name": "Thy-1 membrane glycoprotein", "gene_name": "Thy1", "organism": "Hamster", "refseq_name": "thy-1 membrane glycoprotein", "refseq_ac": [ { "id": "XP_035293708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293708", "type": "external" } ], "gene_names_uniprotkb": "Thy1", "gene_names_refseq": "Thy1", "protein_names_uniprotkb": "Thy-1 membrane glycoprotein; Thy-1 antigen", "protein_names_refseq": "thy-1 membrane glycoprotein", "tax_id": 10029, "disease": "", "pathway": " (cge:100758237)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616562.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005178 integrin binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005783 endoplasmic reticulum;GO:0005925 focal adhesion;GO:0030425 dendrite;GO:0043209 myelin sheath", "go_biological_process": "GO:0001525 angiogenesis;GO:0007229 integrin-mediated signaling pathway;GO:0007267 cell-cell signaling;GO:0051894 positive regulation of focal adhesion assembly;GO:0050860 negative regulation of T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LCE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LCT4-1", "uniprot_id": [ { "id": "A0A8C2LCT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LCT4", "type": "external" } ], "mass": 129750.0, "length": 1171, "protein_name": "Thrombospondin-1", "gene_name": "Thbs1", "organism": "Hamster", "refseq_name": "thrombospondin-1 isoform X1", "refseq_ac": [ { "id": "XP_007642207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642207", "type": "external" } ], "gene_names_uniprotkb": "Thbs1", "gene_names_refseq": "Thbs1", "protein_names_uniprotkb": "Thrombospondin-1; Glycoprotein G", "protein_names_refseq": "thrombospondin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760878)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613968.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007642207.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0005509 calcium ion binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0031012 extracellular matrix;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0006954 inflammatory response;GO:0007155 cell adhesion;GO:0030335 positive regulation of cell migration;GO:0048514 blood vessel morphogenesis;GO:0001937 negative regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LCT4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LCZ8-1", "uniprot_id": [ { "id": "A0A8C2LCZ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LCZ8", "type": "external" } ], "mass": 46169.0, "length": 419, "protein_name": "Inositol-tetrakisphosphate 1-kinase", "gene_name": "Itpk1", "organism": "Hamster", "refseq_name": "inositol-tetrakisphosphate 1-kinase isoform X2", "refseq_ac": [ { "id": "XP_027274965", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274965", "type": "external" } ], "gene_names_uniprotkb": "Itpk1", "gene_names_refseq": "Itpk1", "protein_names_uniprotkb": "Inositol-tetrakisphosphate 1-kinase; 2.7.1.134; 2.7.1.159; Inositol 1,3,4-trisphosphate 5/6-kinase", "protein_names_refseq": "inositol-tetrakisphosphate 1-kinase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768438)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.134", "type": "external" }, { "id": "2.7.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.159", "type": "external" } ], "go_molecular_function": "GO:0047325 inositol-3,4,5,6-tetrakisphosphate 1-kinase activity;GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity;GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0070266 necroptotic process;GO:0032957 inositol trisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LCZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LDB4-1", "uniprot_id": [ { "id": "A0A8C2LDB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LDB4", "type": "external" } ], "mass": 32577.0, "length": 292, "protein_name": "Nucleophosmin", "gene_name": "LOC100761791", "organism": "Hamster", "refseq_name": "nucleophosmin isoform X2", "refseq_ac": [ { "id": "XP_027281003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281003", "type": "external" } ], "gene_names_uniprotkb": "LOC100761791", "gene_names_refseq": "LOC100761791", "protein_names_uniprotkb": "Nucleophosmin; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin", "protein_names_refseq": "nucleophosmin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761791)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0000055 ribosomal large subunit export from nucleus;GO:0006338 chromatin remodeling;GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LDB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LDD7-1", "uniprot_id": [ { "id": "A0A8C2LDD7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LDD7", "type": "external" } ], "mass": 26339.0, "length": 228, "protein_name": "EPH-related receptor tyrosine kinase ligand 7", "gene_name": "Efna5", "organism": "Hamster", "refseq_name": "ephrin-A5 isoform X2", "refseq_ac": [ { "id": "XP_027253537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253537", "type": "external" } ], "gene_names_uniprotkb": "Efna5", "gene_names_refseq": "Efna5", "protein_names_uniprotkb": "EPH-related receptor tyrosine kinase ligand 7", "protein_names_refseq": "ephrin-A5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756587)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046875 ephrin receptor binding;GO:0045499 chemorepellent activity;GO:0005169 neurotrophin TRKB receptor binding", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005912 adherens junction;GO:0009897 external side of plasma membrane;GO:0005604 basement membrane", "go_biological_process": "GO:0051893 regulation of focal adhesion assembly;GO:0032956 regulation of actin cytoskeleton organization;GO:0048013 ephrin receptor signaling pathway;GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0022407 regulation of cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LDD7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LDW4-1", "uniprot_id": [ { "id": "A0A8C2LDW4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LDW4", "type": "external" } ], "mass": 56906.0, "length": 513, "protein_name": "Vacuolar proton pump subunit B", "gene_name": "Atp6v1b1", "organism": "Hamster", "refseq_name": "V-type proton ATPase subunit B, kidney isoform", "refseq_ac": [ { "id": "XP_003512440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512440", "type": "external" } ], "gene_names_uniprotkb": "Atp6v1b1", "gene_names_refseq": "Atp6v1b1", "protein_names_uniprotkb": "Vacuolar proton pump subunit B; V-ATPase subunit B; Vacuolar proton pump subunit B", "protein_names_refseq": "V-type proton ATPase subunit B, kidney isoform", "tax_id": 10029, "disease": "", "pathway": " (cge:100756094)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615442.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005829 cytosol;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0016328 lateral plasma membrane;GO:0005902 microvillus", "go_biological_process": "GO:0042472 inner ear morphogenesis;GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0001503 ossification;GO:0055074 calcium ion homeostasis;GO:0046034 ATP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LDW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LEG0-1", "uniprot_id": [ { "id": "A0A8C2LEG0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LEG0", "type": "external" } ], "mass": 26236.0, "length": 235, "protein_name": "Claudin", "gene_name": "Cldn16", "organism": "Hamster", "refseq_name": "claudin-16", "refseq_ac": [ { "id": "XP_035300467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300467", "type": "external" } ], "gene_names_uniprotkb": "Cldn16", "gene_names_refseq": "Cldn16", "protein_names_uniprotkb": "Claudin", "protein_names_refseq": "claudin-16", "tax_id": 10029, "disease": "", "pathway": " (cge:100751792)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia., [UniProtKB, UniProtKB]; Forms paracellular channels: coassembles with CLDN19 into tight junction strands with cation-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability. Involved in the maintenance of ion gradients along the nephron. In the thick ascending limb (TAL) of Henle's loop, facilitates sodium paracellular permeability from the interstitial compartment to the lumen, contributing to the lumen-positive transepithelial potential that drives paracellular magnesium and calcium reabsorption., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005198 structural molecule activity;GO:0030165 PDZ domain binding;GO:0160187 paracellular tight junction channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0070293 renal absorption;GO:0160184 paracellular transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LEG0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LEI6-1", "uniprot_id": [ { "id": "A0A8C2LEI6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LEI6", "type": "external" } ], "mass": 66421.0, "length": 592, "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "gene_name": "Pth1r", "organism": "Hamster", "refseq_name": "parathyroid hormone/parathyroid hormone-related peptide receptor isoform X2", "refseq_ac": [ { "id": "XP_035299898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299898", "type": "external" } ], "gene_names_uniprotkb": "Pth1r", "gene_names_refseq": "Pth1r", "protein_names_uniprotkb": "Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; Parathyroid hormone 1 receptor", "protein_names_refseq": "parathyroid hormone/parathyroid hormone-related peptide receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769401)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G-protein-coupled receptor for parathyroid hormone (PTH) and for parathyroid hormone-related peptide (PTHLH). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). PTH1R is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. PTHLH dissociates from PTH1R more rapidly than PTH; as consequence, the cAMP response induced by PTHLH decays faster than the response induced by PTH., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0017046 peptide hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0004991 parathyroid hormone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0006874 intracellular calcium ion homeostasis;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LEI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LEL3-1", "uniprot_id": [ { "id": "A0A8C2LEL3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LEL3", "type": "external" } ], "mass": 93523.0, "length": 834, "protein_name": "Paracaspase", "gene_name": "Malt1", "organism": "Hamster", "refseq_name": "mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X3", "refseq_ac": [ { "id": "XP_027258540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258540", "type": "external" } ], "gene_names_uniprotkb": "Malt1", "gene_names_refseq": "Malt1", "protein_names_uniprotkb": "Paracaspase", "protein_names_refseq": "mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770557)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Mediates BCL10 cleavage: MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Involved in the induction of T helper 17 cells (Th17) differentiation. Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation. Also mediates cleavage of N4BP1 in T-cells following TCR-mediated activation, leading to N4BP1 inactivation. May also have ubiquitin ligase activity: binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019209 kinase activator activity;GO:0002020 protease binding;GO:0042802 identical protein binding;GO:0004842 ubiquitin-protein transferase activity;GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0032449 CBM complex;GO:0002096 polkadots", "go_biological_process": "GO:2000321 positive regulation of T-helper 17 cell differentiation;GO:0045087 innate immune response;GO:0042113 B cell activation;GO:0050852 T cell receptor signaling pathway;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LEL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LEX6-1", "uniprot_id": [ { "id": "A0A8C2LEX6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LEX6", "type": "external" } ], "mass": 164036.0, "length": 1361, "protein_name": "Eukaryotic translation initiation factor 3 subunit A", "gene_name": "Eif3a", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 3 subunit A isoform X2", "refseq_ac": [ { "id": "XP_027262652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262652", "type": "external" } ], "gene_names_uniprotkb": "Eif3a; EIF3A; EIF3S10", "gene_names_refseq": "Eif3a", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit A; Eukaryotic translation initiation factor 3 subunit 10; eIF-3-theta; eIF3a", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752118)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0043614 multi-eIF complex", "go_biological_process": "GO:0002188 translation reinitiation;GO:0075522 IRES-dependent viral translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0075525 viral translational termination-reinitiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LEX6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LF72-1", "uniprot_id": [ { "id": "A0A8C2LF72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LF72", "type": "external" } ], "mass": 134820.0, "length": 1276, "protein_name": "Protein crumbs homolog 2", "gene_name": "Crb2", "organism": "Hamster", "refseq_name": "protein crumbs homolog 2 isoform X2", "refseq_ac": [ { "id": "XP_027279406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279406", "type": "external" } ], "gene_names_uniprotkb": "Crb2", "gene_names_refseq": "Crb2", "protein_names_uniprotkb": "Protein crumbs homolog 2; Crumbs-like protein 2", "protein_names_refseq": "protein crumbs homolog 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774304)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0005509 calcium ion binding;GO:0044877 protein-containing complex binding;GO:0019828 aspartic-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016324 apical plasma membrane;GO:0035003 subapical complex;GO:0016327 apicolateral plasma membrane", "go_biological_process": "GO:0010470 regulation of gastrulation;GO:0055111 ingression involved in gastrulation with mouth forming second;GO:0072359 circulatory system development;GO:0048863 stem cell differentiation;GO:0045494 photoreceptor cell maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LF72-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LFN8-1", "uniprot_id": [ { "id": "A0A8C2LFN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LFN8", "type": "external" } ], "mass": 6095.0, "length": 52, "protein_name": "Phospholamban", "gene_name": "Pln", "organism": "Hamster", "refseq_name": "cardiac phospholamban", "refseq_ac": [ { "id": "XP_035296241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296241", "type": "external" } ], "gene_names_uniprotkb": "Pln", "gene_names_refseq": "Pln", "protein_names_uniprotkb": "Phospholamban; PLB", "protein_names_refseq": "cardiac phospholamban", "tax_id": 10029, "disease": "", "pathway": " (cge:100762952)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0044325 transmembrane transporter binding;GO:0042030 ATPase inhibitor activity;GO:0141110 transporter inhibitor activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0033017 sarcoplasmic reticulum membrane;GO:0090534 calcium ion-transporting ATPase complex", "go_biological_process": "GO:0008542 visual learning;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0010459 negative regulation of heart rate;GO:0001675 acrosome assembly;GO:0045475 locomotor rhythm", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LFN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LFT9-1", "uniprot_id": [ { "id": "A0A8C2LFT9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LFT9", "type": "external" } ], "mass": 186662.0, "length": 1650, "protein_name": "eIF-2-alpha kinase GCN2", "gene_name": "Eif2ak4", "organism": "Hamster", "refseq_name": "eIF-2-alpha kinase GCN2 isoform X1", "refseq_ac": [ { "id": "XP_003503470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503470", "type": "external" } ], "gene_names_uniprotkb": "Eif2ak4", "gene_names_refseq": "Eif2ak4", "protein_names_uniprotkb": "eIF-2-alpha kinase GCN2; 2.7.11.1; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein", "protein_names_refseq": "eIF-2-alpha kinase GCN2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613968.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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"https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0005524 ATP binding;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0070417 cellular response to cold;GO:0007399 nervous system development;GO:0034198 cellular response to amino acid starvation;GO:0000077 DNA damage checkpoint signaling;GO:0140469 GCN2-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LFT9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LFV4-1", "uniprot_id": [ { "id": "A0A8C2LFV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LFV4", "type": "external" } ], "mass": 23337.0, "length": 224, "protein_name": "Claudin", "gene_name": "Cldn19", "organism": "Hamster", "refseq_name": "claudin-19", "refseq_ac": [ { "id": 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This record is derived from a genomic sequence (NW_003615864.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0098632 cell-cell adhesion mediator activity;GO:0160187 paracellular tight junction channel activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005923 bicellular tight junction;GO:0016323 basolateral plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0043220 Schmidt-Lanterman incisure", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0034329 cell junction assembly;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LFV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LGL1-1", "uniprot_id": [ { "id": "A0A8C2LGL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LGL1", "type": "external" } ], "mass": 27055.0, "length": 230, "protein_name": "Androgen-dependent TFPI-regulating protein", "gene_name": "Adtrp", "organism": "Hamster", "refseq_name": "androgen-dependent TFPI-regulating protein", "refseq_ac": [ { "id": "XP_003506569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506569", "type": "external" } ], "gene_names_uniprotkb": "Adtrp", "gene_names_refseq": "Adtrp", "protein_names_uniprotkb": "Androgen-dependent TFPI-regulating protein", "protein_names_refseq": "androgen-dependent TFPI-regulating protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100763412)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614251.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0009986 cell surface;GO:0012505 endomembrane system;GO:0005901 caveola", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0010628 positive regulation of gene expression;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0042758 long-chain fatty acid catabolic process;GO:0030195 negative regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LGL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LGU3-1", "uniprot_id": [ { "id": "A0A8C2LGU3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LGU3", "type": "external" } ], "mass": 35606.0, "length": 334, "protein_name": "Erythroferrone", "gene_name": "Erfe", "organism": "Hamster", "refseq_name": "erythroferrone isoform X2", "refseq_ac": [ { "id": "XP_027253383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253383", "type": "external" } ], "gene_names_uniprotkb": "Erfe", "gene_names_refseq": "Erfe", "protein_names_uniprotkb": "Erythroferrone; Complement C1q tumor necrosis factor-related protein 15; Myonectin", "protein_names_refseq": "erythroferrone isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772579)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005179 hormone activity;GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0006879 intracellular iron ion homeostasis;GO:0010507 negative regulation of autophagy;GO:0030514 negative regulation of BMP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LGU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LGY1-1", "uniprot_id": [ { "id": "A0A8C2LGY1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LGY1", "type": "external" } ], "mass": 37512.0, "length": 330, "protein_name": "Serine/threonine-protein phosphatase", "gene_name": "Ppp1ca", "organism": "Hamster", "refseq_name": "serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "refseq_ac": [ { "id": "XP_003509985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509985", "type": "external" } ], "gene_names_uniprotkb": "Ppp1ca", "gene_names_refseq": "Ppp1ca", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase; 3.1.3.16", "protein_names_refseq": "serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "tax_id": 10029, "disease": "", "pathway": " (cge:100760810)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614797.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0098641 cadherin binding involved in cell-cell adhesion;GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005912 adherens junction", "go_biological_process": "GO:0043247 telomere maintenance in response to DNA damage;GO:0051301 cell division;GO:0005977 glycogen metabolic process;GO:0050821 protein stabilization;GO:0045725 positive regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LGY1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LGY3-1", "uniprot_id": [ { "id": "A0A8C2LGY3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LGY3", "type": "external" } ], "mass": 41918.0, "length": 397, "protein_name": "3-ketoacyl-CoA thiolase, mitochondrial isoform X2", "gene_name": "Acaa2", "organism": "Hamster", "refseq_name": "3-ketoacyl-CoA thiolase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027253710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253710", "type": "external" } ], "gene_names_uniprotkb": "Acaa2", "gene_names_refseq": "Acaa2", "protein_names_uniprotkb": "3-ketoacyl-CoA thiolase, mitochondrial isoform X2", "protein_names_refseq": "3-ketoacyl-CoA thiolase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765829)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" }, { "id": "3.5.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" } ], "go_molecular_function": "GO:0003986 acetyl-CoA hydrolase activity;GO:0047617 fatty acyl-CoA hydrolase activity;GO:0003985 acetyl-CoA C-acetyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0071456 cellular response to hypoxia;GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LGY3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LH34-1", "uniprot_id": [ { "id": "A0A8C2LH34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LH34", "type": "external" } ], "mass": 35716.0, "length": 322, "protein_name": "Y-box-binding protein 1 isoform X2", "gene_name": "Ybx1", "organism": "Hamster", "refseq_name": "Y-box-binding protein 1 isoform X1", "refseq_ac": [ { "id": "XP_007651815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651815", "type": "external" } ], "gene_names_uniprotkb": "Ybx1", "gene_names_refseq": "Ybx1", "protein_names_uniprotkb": "Y-box-binding protein 1 isoform X2", "protein_names_refseq": "Y-box-binding protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769813)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 338 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615864.1) and transcript sequence (IACG01091615.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651815.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003729 mRNA binding;GO:0051020 GTPase binding;GO:0035198 miRNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0071204 histone pre-mRNA 3'end processing complex;GO:0005829 cytosol;GO:0045202 synapse;GO:0070062 extracellular exosome;GO:0000932 P-body", "go_biological_process": "GO:1903608 protein localization to cytoplasmic stress granule;GO:0070934 CRD-mediated mRNA stabilization;GO:2000767 positive regulation of cytoplasmic translation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0008544 epidermis development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LH34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LH52-1", "uniprot_id": [ { "id": "A0A8C2LH52_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LH52", "type": "external" } ], "mass": 55438.0, "length": 490, "protein_name": "Protein Mdm4", "gene_name": "Mdm4", "organism": "Hamster", "refseq_name": "protein Mdm4 isoform X1", "refseq_ac": [ { "id": "XP_016830493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830493", "type": "external" } ], "gene_names_uniprotkb": "Mdm4", "gene_names_refseq": "Mdm4", "protein_names_uniprotkb": "Protein Mdm4", "protein_names_refseq": "protein Mdm4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613838.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Contributes to p53/TP53 regulation. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding their transcriptional activation domains. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0061630 ubiquitin protein ligase activity;GO:0002039 p53 binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0071456 cellular response to hypoxia;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LH52-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LHA9-1", "uniprot_id": [ { "id": "A0A8C2LHA9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LHA9", "type": "external" } ], "mass": 87749.0, "length": 793, "protein_name": "Fibroblast growth factor receptor", "gene_name": "Fgfr4", "organism": "Hamster", "refseq_name": "fibroblast growth factor receptor 4", "refseq_ac": [ { "id": "XP_035297433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297433", "type": "external" } ], "gene_names_uniprotkb": "Fgfr4", "gene_names_refseq": "Fgfr4", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "fibroblast growth factor receptor 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765320)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0008201 heparin binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0070857 regulation of bile acid biosynthetic process;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0016477 cell migration;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LHA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LHC6-1", "uniprot_id": [ { "id": "A0A8C2LHC6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LHC6", "type": "external" } ], "mass": 74335.0, "length": 670, "protein_name": "Alkylglycerone-phosphate synthase", "gene_name": "Agps", "organism": "Hamster", "refseq_name": "alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X2", "refseq_ac": [ { "id": "XP_027275935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275935", "type": "external" } ], "gene_names_uniprotkb": "Agps", "gene_names_refseq": "Agps", "protein_names_uniprotkb": "Alkylglycerone-phosphate synthase; 2.5.1.26; Alkyl-DHAP synthase", "protein_names_refseq": "alkyldihydroxyacetonephosphate synthase, peroxisomal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756809)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids., [UniProtKB, UniProtKB]; Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.26", "type": "external" } ], "go_molecular_function": "GO:0008609 alkylglycerone-phosphate synthase activity;GO:0071949 FAD binding", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0008611 ether lipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LHC6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LHP4-1", "uniprot_id": [ { "id": "A0A8C2LHP4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LHP4", "type": "external" } ], "mass": 123483.0, "length": 1103, "protein_name": "DNA polymerase", "gene_name": "Pold1", "organism": "Hamster", "refseq_name": "DNA polymerase delta catalytic subunit isoform X2", "refseq_ac": [ { "id": "XP_027276592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276592", "type": "external" } ], "gene_names_uniprotkb": "Pold1", "gene_names_refseq": "Pold1", "protein_names_uniprotkb": "DNA polymerase; 2.7.7.7", "protein_names_refseq": "DNA polymerase delta catalytic subunit isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773935)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008296 3'-5'-DNA exonuclease activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0000109 nucleotide-excision repair complex;GO:0043625 delta DNA polymerase complex;GO:0005654 nucleoplasm;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006287 base-excision repair, gap-filling;GO:0045004 DNA replication proofreading;GO:0055089 fatty acid homeostasis;GO:0000731 DNA synthesis involved in DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LHP4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LHT7-1", "uniprot_id": [ { "id": "A0A8C2LHT7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LHT7", "type": "external" } ], "mass": 124168.0, "length": 1144, "protein_name": "Phosphodiesterase", "gene_name": "Pde3a", "organism": "Hamster", "refseq_name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X2", "refseq_ac": [ { "id": "XP_027285989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285989", "type": "external" } ], "gene_names_uniprotkb": "Pde3a", "gene_names_refseq": "Pde3a", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774584)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0004119 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity;GO:0046872 metal ion binding;GO:0030284 nuclear estrogen receptor activity;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0043116 negative regulation of vascular permeability;GO:0097190 apoptotic signaling pathway;GO:0071560 cellular response to transforming growth factor beta stimulus;GO:0043117 positive regulation of vascular permeability;GO:0071321 cellular response to cGMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LHT7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LHZ5-1", "uniprot_id": [ { "id": "A0A8C2LHZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LHZ5", "type": "external" } ], "mass": 68786.0, "length": 619, "protein_name": "Transporter", "gene_name": "LOC100774258", "organism": "Hamster", "refseq_name": "sodium-dependent dopamine transporter isoform X3", "refseq_ac": [ { "id": "XP_035295053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295053", "type": "external" } ], "gene_names_uniprotkb": "LOC100774258", "gene_names_refseq": "LOC100774258", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium-dependent dopamine transporter isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100774258)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0046872 metal ion binding;GO:0005330 dopamine:sodium symporter activity;GO:0035240 dopamine binding", "go_cellular_component": "GO:0009986 cell surface;GO:0043025 neuronal cell body;GO:0043679 axon terminus;GO:0016600 flotillin complex", "go_biological_process": "GO:1990384 hyaloid vascular plexus regression;GO:0006865 amino acid transport;GO:0001504 neurotransmitter uptake", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LHZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LI15-1", "uniprot_id": [ { "id": "A0A8C2LI15_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LI15", "type": "external" } ], "mass": 48119.0, "length": 426, "protein_name": "Serine/threonine-protein kinase 25", "gene_name": "Stk25", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase 25 isoform X1", "refseq_ac": [ { "id": "XP_007638246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638246", "type": "external" } ], "gene_names_uniprotkb": "Stk25", "gene_names_refseq": "Stk25", "protein_names_uniprotkb": "Serine/threonine-protein kinase 25; 2.7.11.1; Ste20-like kinase; Sterile 20/oxidant stress-response kinase 1", "protein_names_refseq": "serine/threonine-protein kinase 25 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754386)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 294 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613726.1) and transcript sequence (IACG01091327.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007638246.2. COMPLETENESS: full length., [RefSeq]; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0090443 FAR/SIN/STRIPAK complex", "go_biological_process": "GO:0051683 establishment of Golgi localization;GO:0090168 Golgi reassembly;GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide;GO:0032874 positive regulation of stress-activated MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LI15-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LID2-1", "uniprot_id": [ { "id": "A0A8C2LID2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LID2", "type": "external" } ], "mass": 51675.0, "length": 475, "protein_name": "WASH complex subunit 1 isoform X1", "gene_name": "Washc1", "organism": "Hamster", "refseq_name": "WASH complex subunit 1 isoform X1", "refseq_ac": [ { "id": "XP_027253578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253578", "type": "external" } ], "gene_names_uniprotkb": "Washc1", "gene_names_refseq": "Washc1", "protein_names_uniprotkb": "WASH complex subunit 1 isoform X1", "protein_names_refseq": "WASH complex subunit 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0043014 alpha-tubulin binding;GO:0043015 gamma-tubulin binding;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane;GO:0005770 late endosome", "go_biological_process": "GO:0002468 dendritic cell antigen processing and presentation;GO:0050776 regulation of immune response;GO:0010507 negative regulation of autophagy;GO:0001556 oocyte maturation;GO:0034314 Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LID2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LIU7-1", "uniprot_id": [ { "id": "A0A8C2LIU7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LIU7", "type": "external" } ], "mass": 23398.0, "length": 200, "protein_name": "Sorting nexin-10", "gene_name": "Snx10", "organism": "Hamster", "refseq_name": "sorting nexin-10", "refseq_ac": [ { "id": "XP_003498599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498599", "type": "external" } ], "gene_names_uniprotkb": "Snx10", "gene_names_refseq": "Snx10", "protein_names_uniprotkb": "Sorting nexin-10", "protein_names_refseq": "sorting nexin-10", "tax_id": 10029, "disease": "", "pathway": " (cge:100756513)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613695.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003498599.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding;GO:0005545 1-phosphatidylinositol binding;GO:1901981 phosphatidylinositol phosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0005829 cytosol;GO:0030141 secretory granule", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0006886 intracellular protein transport;GO:0007032 endosome organization;GO:0060271 cilium assembly;GO:0061512 protein localization to cilium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LIU7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LIW3-1", "uniprot_id": [ { "id": "A0A8C2LIW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LIW3", "type": "external" } ], "mass": 79088.0, "length": 736, "protein_name": "Segment polarity protein dishevelled homolog DVL-2 isoform X2", "gene_name": "Dvl2", "organism": "Hamster", "refseq_name": "segment polarity protein dishevelled homolog DVL-2 isoform X2", "refseq_ac": [ { "id": "XP_027282762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282762", "type": "external" } ], "gene_names_uniprotkb": "Dvl2", "gene_names_refseq": "Dvl2", "protein_names_uniprotkb": "Segment polarity protein dishevelled homolog DVL-2 isoform X2", "protein_names_refseq": "segment polarity protein dishevelled homolog DVL-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762587)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0045177 apical part of cell;GO:0030136 clathrin-coated vesicle;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046330 positive regulation of JNK cascade;GO:0035282 segmentation;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LIW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LJ06-1", "uniprot_id": [ { "id": "A0A8C2LJ06_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LJ06", "type": "external" } ], "mass": 107822.0, "length": 941, "protein_name": "Vacuolar protein sorting-associated protein 11 homolog", "gene_name": "Vps11", "organism": "Hamster", "refseq_name": "vacuolar protein sorting-associated protein 11 homolog isoform X1", "refseq_ac": [ { "id": "XP_003511609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511609", "type": "external" } ], "gene_names_uniprotkb": "Vps11", "gene_names_refseq": "Vps11", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 11 homolog", "protein_names_refseq": "vacuolar protein sorting-associated protein 11 homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758112)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615154.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005769 early endosome;GO:0005884 actin filament;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0048284 organelle fusion;GO:0006886 intracellular protein transport;GO:0006914 autophagy;GO:0007032 endosome organization;GO:0007033 vacuole organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LJ06-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LJF9-1", "uniprot_id": [ { "id": "A0A8C2LJF9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LJF9", "type": "external" } ], "mass": 45207.0, "length": 392, "protein_name": "Fucosyltransferase", "gene_name": "Fut7", "organism": "Hamster", "refseq_name": "alpha-(1,3)-fucosyltransferase 7", "refseq_ac": [ { "id": "XP_003514717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514717", "type": "external" } ], "gene_names_uniprotkb": "Fut7", "gene_names_refseq": "Fut7", "protein_names_uniprotkb": "Fucosyltransferase; 2.4.1.-", "protein_names_refseq": "alpha-(1,3)-fucosyltransferase 7", "tax_id": 10029, "disease": "", "pathway": " (cge:100772214)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616838.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.152", "type": "external" } ], "go_molecular_function": "GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0032580 Golgi cisterna membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:1903238 positive regulation of leukocyte tethering or rolling;GO:0009101 glycoprotein biosynthetic process;GO:0002523 leukocyte migration involved in inflammatory response;GO:0006672 ceramide metabolic process;GO:0007566 embryo implantation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LJF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LJX2-1", "uniprot_id": [ { "id": "A0A8C2LJX2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LJX2", "type": "external" } ], "mass": 30305.0, "length": 268, "protein_name": "Interleukin-1", "gene_name": "Il1a", "organism": "Hamster", "refseq_name": "interleukin-1 alpha", "refseq_ac": [ { "id": "XP_035298944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298944", "type": "external" } ], "gene_names_uniprotkb": "Il1a", "gene_names_refseq": "Il1a", "protein_names_uniprotkb": "Interleukin-1", "protein_names_refseq": "interleukin-1 alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100769260)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613665.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005507 copper ion binding;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0033092 positive regulation of immature T cell proliferation in thymus;GO:0001660 fever generation;GO:0006955 immune response;GO:0008285 negative regulation of cell population proliferation;GO:0010575 positive regulation of vascular endothelial growth factor production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LJX2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LKT9-1", "uniprot_id": [ { "id": "A0A8C2LKT9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LKT9", "type": "external" } ], "mass": 104495.0, "length": 926, "protein_name": "Rap guanine nucleotide exchange factor 3", "gene_name": "Rapgef3", "organism": "Hamster", "refseq_name": "rap guanine nucleotide exchange factor 3", "refseq_ac": [ { "id": "XP_007651623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651623", "type": "external" } ], "gene_names_uniprotkb": "Rapgef3", "gene_names_refseq": "Rapgef3", "protein_names_uniprotkb": "Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; cAMP-regulated guanine nucleotide exchange factor I", "protein_names_refseq": "rap guanine nucleotide exchange factor 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767619)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615717.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0030552 cAMP binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0030175 filopodium;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0061028 establishment of endothelial barrier;GO:0032486 Rap protein signal transduction;GO:0001525 angiogenesis;GO:0008306 associative learning", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LKT9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LKX1-1", "uniprot_id": [ { "id": "A0A8C2LKX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LKX1", "type": "external" } ], "mass": 72202.0, "length": 655, "protein_name": "Katanin p80 WD40 repeat-containing subunit B1", "gene_name": "Katnb1", "organism": "Hamster", "refseq_name": "katanin p80 WD40 repeat-containing subunit B1", "refseq_ac": [ { "id": "XP_003509848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509848", "type": "external" } ], "gene_names_uniprotkb": "Katnb1; KATNB1", "gene_names_refseq": "Katnb1", "protein_names_uniprotkb": "Katanin p80 WD40 repeat-containing subunit B1; Katanin p80 subunit B1; p80 katanin", "protein_names_refseq": "katanin p80 WD40 repeat-containing subunit B1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763993)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614770.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0046982 protein heterodimerization activity;GO:0070840 dynein complex binding;GO:0060590 ATPase regulator activity", "go_cellular_component": "GO:0008352 katanin complex;GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0007079 mitotic chromosome movement towards spindle pole;GO:0051013 microtubule severing;GO:0031117 positive regulation of microtubule depolymerization;GO:0051301 cell division;GO:0007026 negative regulation of microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LKX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LL21-1", "uniprot_id": [ { "id": "A0A8C2LL21_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LL21", "type": "external" } ], "mass": 76602.0, "length": 685, "protein_name": "Protein-arginine deiminase", "gene_name": "Padi6", "organism": "Hamster", "refseq_name": "protein-arginine deiminase type-6", "refseq_ac": [ { "id": "XP_016819116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819116", "type": "external" } ], "gene_names_uniprotkb": "Padi6", "gene_names_refseq": "Padi6", "protein_names_uniprotkb": "Protein-arginine deiminase; 3.5.3.15", "protein_names_refseq": "protein-arginine deiminase type-6", "tax_id": 10029, "disease": "", "pathway": " (cge:100770781)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616835.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the deimination of arginine residues of proteins., [UniProtKB, UniProtKB]; Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development. Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos. They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins and proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation. In contrast to other members of the family, does not show protein-arginine deiminase activity due to its inability to bind Ca(2+)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.15", "type": "external" } ], "go_molecular_function": "GO:0004668 protein-arginine deiminase activity;GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0015631 tubulin binding;GO:0140094 structural constituent of cytoplasmic lattice", "go_cellular_component": "GO:0005634 nucleus;GO:0045111 intermediate filament cytoskeleton;GO:0060473 cortical granule;GO:0140095 cytoplasmic lattice", "go_biological_process": "GO:0040016 embryonic cleavage;GO:0140089 protein storage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LL21-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LLD2-1", "uniprot_id": [ { "id": "A0A8C2LLD2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LLD2", "type": "external" } ], "mass": 24343.0, "length": 219, "protein_name": "ADP-sugar pyrophosphatase", "gene_name": "Nudt5", "organism": "Hamster", "refseq_name": "ADP-sugar pyrophosphatase", "refseq_ac": [ { "id": "XP_003496449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496449", "type": "external" } ], "gene_names_uniprotkb": "Nudt5", "gene_names_refseq": "Nudt5", "protein_names_uniprotkb": "ADP-sugar pyrophosphatase; 2.7.7.96; 3.6.1.13; 3.6.1.58; 8-oxo-dGDP phosphatase; Nuclear ATP-synthesis protein NUDIX5; Nucleoside diphosphate-linked moiety X motif 5", "protein_names_refseq": "ADP-sugar pyrophosphatase", "tax_id": 10029, "disease": "", "pathway": " (cge:100772118)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613621.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.58", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.58", "type": "external" }, { "id": "3.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.13", "type": "external" }, { "id": "2.7.7.96", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.96", "type": "external" }, { "id": "3.6.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.16", "type": "external" }, { "id": "3.6.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.53", "type": "external" }, { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.6.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.76", "type": "external" } ], "go_molecular_function": "GO:0044715 8-oxo-dGDP phosphatase activity;GO:0019144 ADP-sugar diphosphatase activity;GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0047631 ADP-ribose diphosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006338 chromatin remodeling;GO:1990966 ATP generation from poly-ADP-D-ribose;GO:0009191 ribonucleoside diphosphate catabolic process;GO:0019303 D-ribose catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LLD2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LLG2-1", "uniprot_id": [ { "id": "A0A8C2LLG2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LLG2", "type": "external" } ], "mass": 44443.0, "length": 395, "protein_name": "RNA demethylase ALKBH5", "gene_name": "Alkbh5", "organism": "Hamster", "refseq_name": "RNA demethylase ALKBH5 isoform X2", "refseq_ac": [ { "id": "XP_027283092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283092", "type": "external" } ], "gene_names_uniprotkb": "Alkbh5", "gene_names_refseq": "Alkbh5", "protein_names_uniprotkb": "RNA demethylase ALKBH5; 1.14.11.53; Alkylated DNA repair protein alkB homolog 5; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5", "protein_names_refseq": "RNA demethylase ALKBH5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755624)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.53", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:1990931 mRNA N6-methyladenosine dioxygenase activity;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0016607 nuclear speck;GO:0042382 paraspeckles", "go_biological_process": "GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus;GO:0006417 regulation of translation;GO:0007283 spermatogenesis;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LLG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LLI9-1", "uniprot_id": [ { "id": "A0A8C2LLI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LLI9", "type": "external" } ], "mass": 57290.0, "length": 508, "protein_name": "Lysosomal Pro-X carboxypeptidase", "gene_name": "LOC100752448", "organism": "Hamster", "refseq_name": "lysosomal Pro-X carboxypeptidase", "refseq_ac": [ { "id": "XP_003507065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507065", "type": "external" } ], "gene_names_uniprotkb": "LOC100752448", "gene_names_refseq": "LOC100752448", "protein_names_uniprotkb": "Lysosomal Pro-X carboxypeptidase; 3.4.16.2; Proline carboxypeptidase; Prolylcarboxypeptidase", "protein_names_refseq": "lysosomal Pro-X carboxypeptidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100752448)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614318.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003507065.1. COMPLETENESS: full length., [RefSeq]; Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0004185 serine-type carboxypeptidase activity;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045178 basal part of cell;GO:0005764 lysosome", "go_biological_process": "GO:0043535 regulation of blood vessel endothelial cell migration;GO:0002003 angiotensin maturation;GO:0003085 negative regulation of systemic arterial blood pressure;GO:0060055 angiogenesis involved in wound healing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LLI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LLR0-1", "uniprot_id": [ { "id": "A0A8C2LLR0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LLR0", "type": "external" } ], "mass": 99500.0, "length": 907, "protein_name": "Chloride channel protein 2", "gene_name": "Clcn2", "organism": "Hamster", "refseq_name": "chloride channel protein 2 isoform X1", "refseq_ac": [ { "id": "XP_003509648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509648", "type": "external" } ], "gene_names_uniprotkb": "Clcn2", "gene_names_refseq": "Clcn2", "protein_names_uniprotkb": "Chloride channel protein 2", "protein_names_refseq": "chloride channel protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769999)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614741.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0017081 chloride channel regulator activity;GO:0005247 voltage-gated chloride channel activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0030424 axon;GO:0043209 myelin sheath;GO:0034707 chloride channel complex;GO:0097450 astrocyte end-foot", "go_biological_process": "GO:0030322 stabilization of membrane potential;GO:0006911 phagocytosis, engulfment;GO:0060075 regulation of resting membrane potential;GO:0032347 regulation of aldosterone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LLR0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LLV4-1", "uniprot_id": [ { "id": "A0A8C2LLV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LLV4", "type": "external" } ], "mass": 41895.0, "length": 384, "protein_name": "Paralemmin-1", "gene_name": "Palm", "organism": "Hamster", "refseq_name": "paralemmin-1 isoform X2", "refseq_ac": [ { "id": "XP_027275251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275251", "type": "external" } ], "gene_names_uniprotkb": "Palm", "gene_names_refseq": "Palm", "protein_names_uniprotkb": "Paralemmin-1; Paralemmin", "protein_names_refseq": "paralemmin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751852)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031750 D3 dopamine receptor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane;GO:0030424 axon", "go_biological_process": "GO:0060160 negative regulation of dopamine receptor signaling pathway;GO:0072659 protein localization to plasma membrane;GO:0008360 regulation of cell shape;GO:0051491 positive regulation of filopodium assembly;GO:0071257 cellular response to electrical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LLV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LM00-1", "uniprot_id": [ { "id": "A0A8C2LM00_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LM00", "type": "external" } ], "mass": 89868.0, "length": 793, "protein_name": "E3 UFM1-protein ligase 1", "gene_name": "Ufl1", "organism": "Hamster", "refseq_name": "E3 UFM1-protein ligase 1 isoform X2", "refseq_ac": [ { "id": "XP_027259242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259242", "type": "external" } ], "gene_names_uniprotkb": "Ufl1", "gene_names_refseq": "Ufl1", "protein_names_uniprotkb": "E3 UFM1-protein ligase 1; E3 UFM1-protein transferase 1", "protein_names_refseq": "E3 UFM1-protein ligase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768952)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016874 ligase activity;GO:0061666 UFM1 ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection;GO:0035861 site of double-strand break", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0060218 hematopoietic stem cell differentiation;GO:0030218 erythrocyte differentiation;GO:0050821 protein stabilization;GO:0031397 negative regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LM00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LMC4-1", "uniprot_id": [ { "id": "A0A8C2LMC4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LMC4", "type": "external" } ], "mass": 23687.0, "length": 212, "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "Socs1", "organism": "Hamster", "refseq_name": "suppressor of cytokine signaling 1 isoform X1", "refseq_ac": [ { "id": "XP_016836049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836049", "type": "external" } ], "gene_names_uniprotkb": "Socs1", "gene_names_refseq": "Socs1", "protein_names_uniprotkb": "Suppressor of cytokine signaling 1", "protein_names_refseq": "suppressor of cytokine signaling 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751218)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 769 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613631.1) and transcript sequence (IACG01047833.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016836049.1. COMPLETENESS: full length., [RefSeq]; Essential negative regulator of type I and type II interferon (IFN) signaling, as well as that of other cytokines, including IL2, IL4, IL6 and leukemia inhibitory factor (LIF). Downregulates cytokine signaling by inhibiting the JAK/STAT signaling pathway. Acts by binding to JAK proteins and to IFNGR1 and inhibiting their kinase activity. In vitro, suppresses Tec protein-tyrosine activity. Regulates IFN-gamma (IFNG)-mediated sensory neuron survival. Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0005159 insulin-like growth factor receptor binding;GO:0046935 1-phosphatidylinositol-3-kinase regulator activity;GO:0019210 kinase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0031410 cytoplasmic vesicle;GO:0005942 phosphatidylinositol 3-kinase complex", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016567 protein ubiquitination;GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT;GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0045591 positive regulation of regulatory T cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LMC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LMT4-1", "uniprot_id": [ { "id": "A0A8C2LMT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LMT4", "type": "external" } ], "mass": 54090.0, "length": 478, "protein_name": "Phosphatidylinositol 4-kinase type 2", "gene_name": "Pi4k2a", "organism": "Hamster", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha isoform X1", "refseq_ac": [ { "id": "XP_007615471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007615471", "type": "external" } ], "gene_names_uniprotkb": "Pi4k2a", "gene_names_refseq": "Pi4k2a", "protein_names_uniprotkb": "Phosphatidylinositol 4-kinase type 2; 2.7.1.67", "protein_names_refseq": "phosphatidylinositol 4-kinase type 2-alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766663)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 504 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613664.1) and transcript sequence (IACG01086329.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007615471.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" } ], "go_molecular_function": "GO:0035651 AP-3 adaptor complex binding;GO:0005524 ATP binding;GO:0004430 1-phosphatidylinositol 4-kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0000139 Golgi membrane;GO:0005739 mitochondrion;GO:0030425 dendrite;GO:0043204 perikaryon", "go_biological_process": "GO:0007032 endosome organization;GO:0007030 Golgi organization;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LMT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LMU6-1", "uniprot_id": [ { "id": "A0A8C2LMU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LMU6", "type": "external" } ], "mass": 33738.0, "length": 298, "protein_name": "Golgi phosphoprotein 3 isoform X2", "gene_name": "Golph3", "organism": "Hamster", "refseq_name": "Golgi phosphoprotein 3 isoform X2", "refseq_ac": [ { "id": "XP_027257053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257053", "type": "external" } ], "gene_names_uniprotkb": "Golph3", "gene_names_refseq": "Golph3", "protein_names_uniprotkb": "Golgi phosphoprotein 3 isoform X2", "protein_names_refseq": "Golgi phosphoprotein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750982)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0140312 cargo adaptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0032580 Golgi cisterna membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0072752 cellular response to rapamycin;GO:0045053 protein retention in Golgi apparatus;GO:0090164 asymmetric Golgi ribbon formation;GO:0043066 negative regulation of apoptotic process;GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LMU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F2J4-1", "uniprot_id": [ { "id": "A0A9J7F2J4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F2J4", "type": "external" } ], "mass": 108204.0, "length": 950, "protein_name": "Exostosin-like 3", "gene_name": "Extl3", "organism": "Hamster", "refseq_name": "exostosin-like 3 isoform X1", "refseq_ac": [ { "id": "XP_027246121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246121", "type": "external" } ], "gene_names_uniprotkb": "Extl3", "gene_names_refseq": "Extl3", "protein_names_uniprotkb": "Exostosin-like 3; 2.4.1.223; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostosis-like protein 3", "protein_names_refseq": "exostosin-like 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751999)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal-Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elongation (GlcNAcT-II activity). Lacks glucuronyl transferase II (GlcAT-II) activity. Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Through the synthesis of HS, regulates postnatal pancreatic islet maturation and insulin secretion., [UniProtKB, UniProtKB, UniProtKB]; Receptor for REG3A, REG3B and REG3G, induces the activation of downstream signaling pathways such as PI3K-AKT or RAS-RAF-MEK-ERK signaling pathway. Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. Required for the inhibition of skin inflammation mediated by REG3A through the activation of PI3K-AKT-STAT3 pathway. Required for the function of REG3A and REG3G in glucose tolerance in pancreas. Expressed in microglia, is activated by nociceptor-derived REG3G in response to endotoxins, leading to the inhibition of kynurenine pathway to prevent endotoxic death., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.223", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.223", "type": "external" } ], "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0000287 magnesium ion binding;GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045617 negative regulation of keratinocyte differentiation;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0015012 heparan sulfate proteoglycan biosynthetic process;GO:0010838 positive regulation of keratinocyte proliferation;GO:0106015 negative regulation of inflammatory response to wounding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F2J4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LXS7-1", "uniprot_id": [ { "id": "A0A8C2LXS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LXS7", "type": "external" } ], "mass": 103004.0, "length": 912, "protein_name": "Protein ECT2 isoform X1", "gene_name": "Ect2", "organism": "Hamster", "refseq_name": "protein ECT2 isoform X1", "refseq_ac": [ { "id": "XP_003499838", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499838", "type": "external" } ], "gene_names_uniprotkb": "Ect2", "gene_names_refseq": "Ect2", "protein_names_uniprotkb": "Protein ECT2 isoform X1", "protein_names_refseq": "protein ECT2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754674)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613753.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0042803 protein homodimerization activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005938 cell cortex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0007399 nervous system development;GO:0035556 intracellular signal transduction;GO:0000281 mitotic cytokinesis;GO:2000431 regulation of cytokinesis, actomyosin contractile ring assembly;GO:0042307 positive regulation of protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LXS7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPC9-1", "uniprot_id": [ { "id": "A0A9J7FPC9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPC9", "type": "external" } ], "mass": 61772.0, "length": 546, "protein_name": "Histone acetyltransferase KAT5", "gene_name": "Kat5", "organism": "Hamster", "refseq_name": "histone acetyltransferase KAT5 isoform X1", "refseq_ac": [ { "id": "XP_007651506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651506", "type": "external" } ], "gene_names_uniprotkb": "Kat5", "gene_names_refseq": "Kat5", "protein_names_uniprotkb": "Histone acetyltransferase KAT5; 2.3.1.48; 60 kDa Tat-interactive protein; Histone acetyltransferase HTATIP; Lysine acetyltransferase 5; Protein 2-hydroxyisobutyryltransferase KAT5; Protein acetyltransferase KAT5; Protein crotonyltransferase KAT5; Protein lactyltransferase KAT5", "protein_names_refseq": "histone acetyltransferase KAT5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761603)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615656.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0046972 histone H4K16 acetyltransferase activity", "go_cellular_component": "GO:0031981 nuclear lumen;GO:0000922 spindle pole;GO:0035267 NuA4 histone acetyltransferase complex;GO:0048471 perinuclear region of cytoplasm;GO:0000776 kinetochore", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0000724 double-strand break repair via homologous recombination;GO:1901701 cellular response to oxygen-containing compound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKM2-1", "uniprot_id": [ { "id": "A0A8C2QKM2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKM2", "type": "external" } ], "mass": 57403.0, "length": 505, "protein_name": "tRNA (guanine(37)-N1)-methyltransferase", "gene_name": "Trmt5", "organism": "Hamster", "refseq_name": "tRNA (guanine(37)-N1)-methyltransferase isoform X1", "refseq_ac": [ { "id": "XP_007651535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651535", "type": "external" } ], "gene_names_uniprotkb": "Trmt5; TRM5; TRMT5", "gene_names_refseq": "Trmt5", "protein_names_uniprotkb": "tRNA (guanine(37)-N1)-methyltransferase; 2.1.1.228; M1G-methyltransferase; tRNA [GM37] methyltransferase; tRNA methyltransferase 5 homolog", "protein_names_refseq": "tRNA (guanine(37)-N1)-methyltransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752861)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615679.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding., [UniProtKB, UniProtKB, UniProtKB]; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.228", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.228", "type": "external" } ], "go_molecular_function": "GO:0052906 tRNA (guanine(37)-N1)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0002939 tRNA N1-guanine methylation;GO:0070901 mitochondrial tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKM2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FB39-1", "uniprot_id": [ { "id": "A0A9J7FB39_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FB39", "type": "external" } ], "mass": 108861.0, "length": 977, "protein_name": "Ephrin type-A receptor 2", "gene_name": "Epha2", "organism": "Hamster", "refseq_name": "ephrin type-A receptor 2 isoform X2", "refseq_ac": [ { "id": "XP_027255711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255711", "type": "external" } ], "gene_names_uniprotkb": "Epha2", "gene_names_refseq": "Epha2", "protein_names_uniprotkb": "Ephrin type-A receptor 2; 2.7.10.1", "protein_names_refseq": "ephrin type-A receptor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752851)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0030425 dendrite;GO:0032587 ruffle membrane;GO:0031258 lamellipodium membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0030855 epithelial cell differentiation;GO:0006915 apoptotic process;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FB39-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MIT8-1", "uniprot_id": [ { "id": "A0A8C2MIT8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MIT8", "type": "external" } ], "mass": 42436.0, "length": 371, "protein_name": "type I protein arginine methyltransferase", "gene_name": "Prmt1", "organism": "Hamster", "refseq_name": "protein arginine N-methyltransferase 1 isoform X3", "refseq_ac": [ { "id": "XP_027276514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276514", "type": "external" } ], "gene_names_uniprotkb": "Prmt1", "gene_names_refseq": "Prmt1", "protein_names_uniprotkb": "type I protein arginine methyltransferase; 2.1.1.319", "protein_names_refseq": "protein arginine N-methyltransferase 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765197)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" }, { "id": "2.1.1.321", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.321", "type": "external" } ], "go_molecular_function": "GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054 histone methyltransferase activity;GO:0035241 protein-arginine omega-N monomethyltransferase activity;GO:0042802 identical protein binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0034709 methylosome", "go_biological_process": "GO:0032259 methylation;GO:1904263 positive regulation of TORC1 signaling;GO:0008284 positive regulation of cell population proliferation;GO:0031175 neuron projection development;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MIT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZI5-1", "uniprot_id": [ { "id": "A0A9J7EZI5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZI5", "type": "external" } ], "mass": 89455.0, "length": 802, "protein_name": "Peroxisomal acyl-coenzyme A oxidase 3", "gene_name": "Acox3", "organism": "Hamster", "refseq_name": "peroxisomal acyl-coenzyme A oxidase 3 isoform X1", "refseq_ac": [ { "id": "XP_007649806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649806", "type": "external" } ], "gene_names_uniprotkb": "Acox3", "gene_names_refseq": "Acox3", "protein_names_uniprotkb": "Peroxisomal acyl-coenzyme A oxidase 3; 1.3.3.6; Branched-chain acyl-CoA oxidase; Pristanoyl-CoA oxidase", "protein_names_refseq": "peroxisomal acyl-coenzyme A oxidase 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767060)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613629.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Oxidizes the CoA-esters of 2-methyl-branched fatty acids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" } ], "go_molecular_function": "GO:0005504 fatty acid binding;GO:0071949 FAD binding;GO:0016402 pristanoyl-CoA oxidase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase;GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FB79-1", "uniprot_id": [ { "id": "A0A9J7FB79_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FB79", "type": "external" } ], "mass": 53571.0, "length": 485, "protein_name": "Retinoic acid receptor gamma isoform X1", "gene_name": "Rarg", "organism": "Hamster", "refseq_name": "retinoic acid receptor gamma isoform X1", "refseq_ac": [ { "id": "XP_003507258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507258", "type": "external" } ], "gene_names_uniprotkb": "Rarg", "gene_names_refseq": "Rarg", "protein_names_uniprotkb": "Retinoic acid receptor gamma isoform X1", "protein_names_refseq": "retinoic acid receptor gamma isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769591)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614339.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0035259 nuclear glucocorticoid receptor binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0002068 glandular epithelial cell development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FB79-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDC1-1", "uniprot_id": [ { "id": "A0A9J7FDC1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDC1", "type": "external" } ], "mass": 237992.0, "length": 2064, "protein_name": "Unconventional myosin-X", "gene_name": "Myo10", "organism": "Hamster", "refseq_name": "unconventional myosin-X isoform X5", "refseq_ac": [ { "id": "XP_027255838", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255838", "type": "external" } ], "gene_names_uniprotkb": "Myo10", "gene_names_refseq": "Myo10", "protein_names_uniprotkb": "Unconventional myosin-X; Unconventional myosin-10", "protein_names_refseq": "unconventional myosin-X isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100766312)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as a plus end-directed motor. Moves with higher velocity and takes larger steps on actin bundles than on single actin filaments. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0051015 actin filament binding;GO:0060002 plus-end directed microfilament motor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030175 filopodium;GO:0001726 ruffle;GO:0016459 myosin complex", "go_biological_process": "GO:0007165 signal transduction;GO:0008360 regulation of cell shape;GO:0051489 regulation of filopodium assembly;GO:0030705 cytoskeleton-dependent intracellular transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDC1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FVR0-1", "uniprot_id": [ { "id": "A0A9J7FVR0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FVR0", "type": "external" } ], "mass": 19001.0, "length": 165, "protein_name": "Oxidized purine nucleoside triphosphate hydrolase", "gene_name": "Nudt1", "organism": "Hamster", "refseq_name": "7,8-dihydro-8-oxoguanine triphosphatase isoform X3", "refseq_ac": [ { "id": "XP_027269305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269305", "type": "external" } ], "gene_names_uniprotkb": "Nudt1", "gene_names_refseq": "Nudt1", "protein_names_uniprotkb": "Oxidized purine nucleoside triphosphate hydrolase; 2-hydroxy-dATP diphosphatase; 3.6.1.56; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-dGTPase; Methylated purine nucleoside triphosphate hydrolase; Nucleoside diphosphate-linked moiety X motif 1", "protein_names_refseq": "7,8-dihydro-8-oxoguanine triphosphatase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770207)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool. Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy-dATP) into 2-oxo-dAMP. Also has a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP. Through the hydrolysis of oxidized purine nucleoside triphosphates, prevents their incorporation into DNA and the subsequent transversions A:T to C:G and G:C to T:A. Also catalyzes the hydrolysis of methylated purine nucleoside triphosphate preventing their integration into DNA. Through this antimutagenic activity protects cells from oxidative stress., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.56", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity;GO:0008828 dATP diphosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042262 DNA protection", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FVR0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N0P9-1", "uniprot_id": [ { "id": "A0A8C2N0P9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N0P9", "type": "external" } ], "mass": 15089.0, "length": 136, "protein_name": "Calcitonin", "gene_name": "LOC100772276", "organism": "Hamster", "refseq_name": "calcitonin isoform X1", "refseq_ac": [ { "id": "XP_035297211", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297211", "type": "external" } ], "gene_names_uniprotkb": "LOC100772276", "gene_names_refseq": "LOC100772276", "protein_names_uniprotkb": "Calcitonin", "protein_names_refseq": "calcitonin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772276)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcitonin is a peptide hormone that causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Calcitonin function is mediated by the calcitonin receptor/CALCR and the CALCR-RAMP2 (AMYR2) receptor complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031716 calcitonin receptor binding;GO:0005179 hormone activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0045892 negative regulation of DNA-templated transcription;GO:0002548 monocyte chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N0P9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MUJ7-1", "uniprot_id": [ { "id": "A0A8C2MUJ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MUJ7", "type": "external" } ], "mass": 76998.0, "length": 706, "protein_name": "Drebrin", "gene_name": "Dbn1", "organism": "Hamster", "refseq_name": "drebrin isoform X3", "refseq_ac": [ { "id": "XP_027265588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265588", "type": "external" } ], "gene_names_uniprotkb": "Dbn1", "gene_names_refseq": "Dbn1", "protein_names_uniprotkb": "Drebrin; Developmentally-regulated brain protein", "protein_names_refseq": "drebrin isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100763853)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines. Involved in memory-related synaptic plasticity in the hippocampus., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005884 actin filament;GO:0014069 postsynaptic density;GO:0030027 lamellipodium;GO:0030425 dendrite;GO:0030426 growth cone", "go_biological_process": "GO:0048812 neuron projection morphogenesis;GO:0098974 postsynaptic actin cytoskeleton organization;GO:0045773 positive regulation of axon extension;GO:0061003 positive regulation of dendritic spine morphogenesis;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MUJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCP7-1", "uniprot_id": [ { "id": "A0A8C2QCP7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCP7", "type": "external" } ], "mass": 274366.0, "length": 2363, "protein_name": "Spectrin beta chain", "gene_name": "Sptbn1", "organism": "Hamster", "refseq_name": "spectrin beta chain, non-erythrocytic 1 isoform X3", "refseq_ac": [ { "id": "XP_027243734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243734", "type": "external" } ], "gene_names_uniprotkb": "Sptbn1", "gene_names_refseq": "Sptbn1", "protein_names_uniprotkb": "Spectrin beta chain", "protein_names_refseq": "spectrin beta chain, non-erythrocytic 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100763016)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005200 structural constituent of cytoskeleton;GO:0005516 calmodulin binding;GO:0005543 phospholipid binding;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031430 M band;GO:0008091 spectrin", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0051693 actin filament capping;GO:0021556 central nervous system formation;GO:0007009 plasma membrane organization;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCP7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCZ7-1", "uniprot_id": [ { "id": "A0A8C2QCZ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCZ7", "type": "external" } ], "mass": 108543.0, "length": 932, "protein_name": "Anoctamin", "gene_name": "Ano6", "organism": "Hamster", "refseq_name": "anoctamin-6 isoform X4", "refseq_ac": [ { "id": "XP_027252180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252180", "type": "external" } ], "gene_names_uniprotkb": "Ano6", "gene_names_refseq": "Ano6", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "anoctamin-6 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100757664)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0005254 chloride channel activity;GO:0005227 calcium-activated cation channel activity;GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0005247 voltage-gated chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0061589 calcium activated phosphatidylserine scrambling;GO:0061590 calcium activated phosphatidylcholine scrambling;GO:0090026 positive regulation of monocyte chemotaxis;GO:0030501 positive regulation of bone mineralization;GO:0002543 activation of blood coagulation via clotting cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEJ5-1", "uniprot_id": [ { "id": "A0A8C2QEJ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEJ5", "type": "external" } ], "mass": 152490.0, "length": 1364, "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "Nsd2", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase NSD2 isoform X1", "refseq_ac": [ { "id": "XP_007642806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642806", "type": "external" } ], "gene_names_uniprotkb": "Nsd2", "gene_names_refseq": "Nsd2", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase NSD2; 2.1.1.357; Multiple myeloma SET domain-containing protein; Nuclear SET domain-containing protein 2", "protein_names_refseq": "histone-lysine N-methyltransferase NSD2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763780)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 118 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614033.1) and transcript sequence (IACG01046470.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0140954 histone H3K36 dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LNA1-1", "uniprot_id": [ { "id": "A0A8C2LNA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LNA1", "type": "external" } ], "mass": 112233.0, "length": 1020, "protein_name": "Sodium/potassium-transporting ATPase subunit alpha", "gene_name": "Atp1a2", "organism": "Hamster", "refseq_name": "sodium/potassium-transporting ATPase subunit alpha-2", "refseq_ac": [ { "id": "XP_003500332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500332", "type": "external" } ], "gene_names_uniprotkb": "Atp1a2", "gene_names_refseq": "Atp1a2", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit alpha", "protein_names_refseq": "sodium/potassium-transporting ATPase subunit alpha-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763478)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613783.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005391 P-type sodium:potassium-exchanging transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0042995 cell projection;GO:0030315 T-tubule;GO:0005890 sodium:potassium-exchanging ATPase complex", "go_biological_process": "GO:0008015 blood circulation;GO:0008016 regulation of heart contraction;GO:0009612 response to mechanical stimulus;GO:0006883 intracellular sodium ion homeostasis;GO:0007154 cell communication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LNA1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LNG9-1", "uniprot_id": [ { "id": "A0A8C2LNG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LNG9", "type": "external" } ], "mass": 68581.0, "length": 619, "protein_name": "Replication protein A subunit", "gene_name": "Rpa1", "organism": "Hamster", "refseq_name": "replication protein A 70 kDa DNA-binding subunit isoform X2", "refseq_ac": [ { "id": "XP_003514530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514530", "type": "external" } ], "gene_names_uniprotkb": "Rpa1", "gene_names_refseq": "Rpa1", "protein_names_uniprotkb": "Replication protein A subunit", "protein_names_refseq": "replication protein A 70 kDa DNA-binding subunit isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772412)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 413 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616642.1) and transcript sequence (JP062658.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003514530.1. COMPLETENESS: full length., [RefSeq]; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0098505 G-rich strand telomeric DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0140463 chromatin-protein adaptor activity", "go_cellular_component": "GO:0001673 male germ cell nucleus;GO:0016605 PML body;GO:0035861 site of double-strand break;GO:0005662 DNA replication factor A complex;GO:0000800 lateral element", "go_biological_process": "GO:1990166 protein localization to site of double-strand break;GO:0006284 base-excision repair;GO:0000723 telomere maintenance;GO:0006260 DNA replication;GO:0006298 mismatch repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LNG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LNM5-1", "uniprot_id": [ { "id": "A0A8C2LNM5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LNM5", "type": "external" } ], "mass": 40482.0, "length": 360, "protein_name": "Protein Wnt", "gene_name": "Wnt2", "organism": "Hamster", "refseq_name": "protein Wnt-2", "refseq_ac": [ { "id": "XP_003500825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500825", "type": "external" } ], "gene_names_uniprotkb": "Wnt2", "gene_names_refseq": "Wnt2", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752722)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613810.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071560 cellular response to transforming growth factor beta stimulus;GO:0048146 positive regulation of fibroblast proliferation;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LNM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZZ8-1", "uniprot_id": [ { "id": "A0A9J7EZZ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZZ8", "type": "external" } ], "mass": 136352.0, "length": 1194, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp11a", "organism": "Hamster", "refseq_name": "probable phospholipid-transporting ATPase IH isoform X6", "refseq_ac": [ { "id": "XP_027243641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243641", "type": "external" } ], "gene_names_uniprotkb": "Atp11a", "gene_names_refseq": "Atp11a", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "probable phospholipid-transporting ATPase IH isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100761170)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090555 phosphatidylethanolamine flippase activity;GO:0140346 phosphatidylserine flippase activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0005789 endoplasmic reticulum membrane;GO:1990531 phospholipid-translocating ATPase complex", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0045332 phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LNW7-1", "uniprot_id": [ { "id": "A0A8C2LNW7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LNW7", "type": "external" } ], "mass": 81863.0, "length": 745, "protein_name": "Junction plakoglobin", "gene_name": "Jup", "organism": "Hamster", "refseq_name": "junction plakoglobin", "refseq_ac": [ { "id": "XP_003504710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504710", "type": "external" } ], "gene_names_uniprotkb": "Jup", "gene_names_refseq": "Jup", "protein_names_uniprotkb": "Junction plakoglobin", "protein_names_refseq": "junction plakoglobin", "tax_id": 10029, "disease": "", "pathway": " (cge:100760007)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614078.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0045296 cadherin binding;GO:0019903 protein phosphatase binding;GO:0045294 alpha-catenin binding;GO:0106006 cytoskeletal protein-membrane anchor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005912 adherens junction;GO:0005882 intermediate filament;GO:0014704 intercalated disc;GO:0030018 Z disc", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0016477 cell migration;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LNW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LP68-1", "uniprot_id": [ { "id": "A0A8C2LP68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LP68", "type": "external" } ], "mass": 37892.0, "length": 362, "protein_name": "Eukaryotic translation initiation factor 3 subunit F", "gene_name": "Eif3f", "organism": "Hamster", "refseq_name": "eukaryotic translation initiation factor 3 subunit F isoform X1", "refseq_ac": [ { "id": "XP_007649422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649422", "type": "external" } ], "gene_names_uniprotkb": "Eif3f; EIF3F; EIF3S5", "gene_names_refseq": "Eif3f", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit F; Eukaryotic translation initiation factor 3 subunit 5; eIF-3-epsilon; eIF3 p47; eIF3f", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit F isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769028)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 501 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614918.1) and transcript sequence (IACG01090743.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007649422.2. COMPLETENESS: full length., [RefSeq]; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP]; Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0003743 translation initiation factor activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0031369 translation initiation factor binding;GO:0140492 metal-dependent deubiquitinase activity", "go_cellular_component": "GO:0045202 synapse;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m", "go_biological_process": "GO:0075522 IRES-dependent viral translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LP68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LP77-1", "uniprot_id": [ { "id": "A0A8C2LP77_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LP77", "type": "external" } ], "mass": 22238.0, "length": 197, "protein_name": "Ubiquitin-conjugating enzyme E2 T", "gene_name": "Ube2t", "organism": "Hamster", "refseq_name": "ubiquitin-conjugating enzyme E2 T isoform X1", "refseq_ac": [ { "id": "XP_003498901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498901", "type": "external" } ], "gene_names_uniprotkb": "Ube2t", "gene_names_refseq": "Ube2t", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 T; 2.3.2.23; E2 ubiquitin-conjugating enzyme T; Ubiquitin carrier protein T; Ubiquitin-protein ligase T", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 T isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613706.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0031625 ubiquitin protein ligase binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "", "go_biological_process": "GO:0006281 DNA repair;GO:0070979 protein K11-linked ubiquitination;GO:0051865 protein autoubiquitination;GO:0070936 protein K48-linked ubiquitination;GO:0070534 protein K63-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LP77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LTF6-1", "uniprot_id": [ { "id": "A0A8C2LTF6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LTF6", "type": "external" } ], "mass": 92715.0, "length": 809, "protein_name": "Short transient receptor potential channel 1", "gene_name": "Trpc1", "organism": "Hamster", "refseq_name": "short transient receptor potential channel 1 isoform X1", "refseq_ac": [ { "id": "XP_003495537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495537", "type": "external" } ], "gene_names_uniprotkb": "Trpc1", "gene_names_refseq": "Trpc1", "protein_names_uniprotkb": "Short transient receptor potential channel 1; Transient receptor protein 1", "protein_names_refseq": "short transient receptor potential channel 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613594.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0015279 store-operated calcium channel activity;GO:0005102 signaling receptor binding;GO:0051117 ATPase binding", "go_cellular_component": "GO:0034703 cation channel complex;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0051480 regulation of cytosolic calcium ion concentration;GO:0051592 response to calcium ion;GO:0051281 positive regulation of release of sequestered calcium ion into cytosol;GO:0042438 melanin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LTF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LQZ5-1", "uniprot_id": [ { "id": "A0A8C2LQZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LQZ5", "type": "external" } ], "mass": 59037.0, "length": 522, "protein_name": "Target of rapamycin complex 2 subunit MAPKAP1", "gene_name": "Mapkap1", "organism": "Hamster", "refseq_name": "target of rapamycin complex 2 subunit MAPKAP1 isoform X7", "refseq_ac": [ { "id": "XP_027279529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279529", "type": "external" } ], "gene_names_uniprotkb": "Mapkap1", "gene_names_refseq": "Mapkap1", "protein_names_uniprotkb": "Target of rapamycin complex 2 subunit MAPKAP1; Stress-activated map kinase-interacting protein 1", "protein_names_refseq": "target of rapamycin complex 2 subunit MAPKAP1 isoform X7", "tax_id": 10029, "disease": "", "pathway": " (cge:100755792)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0140767 enzyme-substrate adaptor activity;GO:0004674 protein serine/threonine kinase activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0038203 TORC2 signaling;GO:0046580 negative regulation of Ras protein signal transduction;GO:0032869 cellular response to insulin stimulus;GO:1900407 regulation of cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LQZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LPL6-1", "uniprot_id": [ { "id": "A0A8C2LPL6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LPL6", "type": "external" } ], "mass": 130767.0, "length": 1147, "protein_name": "Alpha-mannosidase", "gene_name": "Man2a1", "organism": "Hamster", "refseq_name": "alpha-mannosidase 2", "refseq_ac": [ { "id": "XP_003499415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499415", "type": "external" } ], "gene_names_uniprotkb": "Man2a1", "gene_names_refseq": "Man2a1", "protein_names_uniprotkb": "Alpha-mannosidase; 3.2.1.-", "protein_names_refseq": "alpha-mannosidase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757006)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613732.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005797 Golgi medial cisterna;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0006491 N-glycan processing;GO:0006013 mannose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LPL6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LPQ1-1", "uniprot_id": [ { "id": "A0A8C2LPQ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LPQ1", "type": "external" } ], "mass": 106057.0, "length": 943, "protein_name": "Lysine-specific demethylase 7A", "gene_name": "Kdm7a", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 7A isoform X2", "refseq_ac": [ { "id": "XP_027247313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247313", "type": "external" } ], "gene_names_uniprotkb": "Kdm7a", "gene_names_refseq": "Kdm7a", "protein_names_uniprotkb": "Lysine-specific demethylase 7A; 1.14.11.65; JmjC domain-containing histone demethylation protein 1D; Lysine-specific demethylase 7; [histone H3]-dimethyl-L-lysine9 demethylase 7A", "protein_names_refseq": "lysine-specific demethylase 7A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773228)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" }, { "id": "1.14.99.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66", "type": "external" } ], "go_molecular_function": "GO:0035575 histone H4K20 demethylase activity;GO:0051864 histone H3K36 demethylase activity;GO:0005506 iron ion binding;GO:0008270 zinc ion binding;GO:0071558 histone H3K27me2/H3K27me3 demethylase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LPQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LQ49-1", "uniprot_id": [ { "id": "A0A8C2LQ49_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LQ49", "type": "external" } ], "mass": 53074.0, "length": 461, "protein_name": "Phosphatidate cytidylyltransferase", "gene_name": "Cds1", "organism": "Hamster", "refseq_name": "phosphatidate cytidylyltransferase 1 isoform X2", "refseq_ac": [ { "id": "XP_027244326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244326", "type": "external" } ], "gene_names_uniprotkb": "Cds1", "gene_names_refseq": "Cds1", "protein_names_uniprotkb": "Phosphatidate cytidylyltransferase; 2.7.7.41", "protein_names_refseq": "phosphatidate cytidylyltransferase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761973)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.41", "type": "external" } ], "go_molecular_function": "GO:0004605 phosphatidate cytidylyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045600 positive regulation of fat cell differentiation;GO:0006661 phosphatidylinositol biosynthetic process;GO:0140042 lipid droplet formation;GO:0016024 CDP-diacylglycerol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LQ49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LQS6-1", "uniprot_id": [ { "id": "A0A8C2LQS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LQS6", "type": "external" } ], "mass": 60708.0, "length": 547, "protein_name": "1-phosphatidylinositol-4-phosphate 5-kinase", "gene_name": "Pip5k1a", "organism": "Hamster", "refseq_name": "phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X2", "refseq_ac": [ { "id": "XP_016827500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827500", "type": "external" } ], "gene_names_uniprotkb": "Pip5k1a", "gene_names_refseq": "Pip5k1a", "protein_names_uniprotkb": "1-phosphatidylinositol-4-phosphate 5-kinase; 2.7.1.68", "protein_names_refseq": "phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613699.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.68", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019900 kinase binding;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0030027 lamellipodium;GO:0032587 ruffle membrane;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0030036 actin cytoskeleton organization;GO:0060326 cell chemotaxis;GO:0048041 focal adhesion assembly;GO:0097178 ruffle assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LQS6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FDA5-1", "uniprot_id": [ { "id": "A0A9J7FDA5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FDA5", "type": "external" } ], "mass": 42420.0, "length": 380, "protein_name": "Cytosolic acyl coenzyme A thioester hydrolase", "gene_name": "Acot7", "organism": "Hamster", "refseq_name": "cytosolic acyl coenzyme A thioester hydrolase isoform X4", "refseq_ac": [ { "id": "XP_027254168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254168", "type": "external" } ], "gene_names_uniprotkb": "Acot7", "gene_names_refseq": "Acot7", "protein_names_uniprotkb": "Cytosolic acyl coenzyme A thioester hydrolase; 3.1.2.2; Acyl-CoA thioesterase 7; Brain acyl-CoA hydrolase; CTE-IIa; Long chain acyl-CoA thioester hydrolase", "protein_names_refseq": "cytosolic acyl coenzyme A thioester hydrolase isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100755154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "3.5.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" } ], "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity;GO:0052816 long-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006637 acyl-CoA metabolic process;GO:0009062 fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FDA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LQV5-1", "uniprot_id": [ { "id": "A0A8C2LQV5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LQV5", "type": "external" } ], "mass": 32277.0, "length": 291, "protein_name": "Kidney mitochondrial carrier protein 1", "gene_name": "Slc25a30", "organism": "Hamster", "refseq_name": "kidney mitochondrial carrier protein 1", "refseq_ac": [ { "id": "XP_007639199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639199", "type": "external" } ], "gene_names_uniprotkb": "Slc25a30", "gene_names_refseq": "Slc25a30", "protein_names_uniprotkb": "Kidney mitochondrial carrier protein 1", "protein_names_refseq": "kidney mitochondrial carrier protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767752)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613785.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005452 solute:inorganic anion antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015698 inorganic anion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LQV5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LR22-1", "uniprot_id": [ { "id": "A0A8C2LR22_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LR22", "type": "external" } ], "mass": 119381.0, "length": 1045, "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "gene_name": "Dhx16", "organism": "Hamster", "refseq_name": "pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform X2", "refseq_ac": [ { "id": "XP_027244353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244353", "type": "external" } ], "gene_names_uniprotkb": "Dhx16", "gene_names_refseq": "Dhx16", "protein_names_uniprotkb": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; 3.6.4.13; DEAH-box protein 16", "protein_names_refseq": "pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756749)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for pre-mRNA splicing as a component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Also plays a role in innate antiviral response by acting as a pattern recognition receptor sensing splicing signals in viral RNA. Mechanistically, TRIM6 promotes the interaction between unanchored 'Lys-48'-polyubiquitin chains and DHX16, leading to DHX16 interaction with RIGI and ssRNA to amplify RIGI-dependent innate antiviral immune responses., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0071005 U2-type precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0140374 antiviral innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LR22-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LR41-1", "uniprot_id": [ { "id": "A0A8C2LR41_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LR41", "type": "external" } ], "mass": 100478.0, "length": 888, "protein_name": "Kinesin-like protein", "gene_name": "Kif20a", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF20A isoform X2", "refseq_ac": [ { "id": "XP_035296094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296094", "type": "external" } ], "gene_names_uniprotkb": "Kif20a", "gene_names_refseq": "Kif20a", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF20A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773707)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0019901 protein kinase binding;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0030496 midbody;GO:0005876 spindle microtubule;GO:0072686 mitotic spindle", "go_biological_process": "GO:0015031 protein transport;GO:0090307 mitotic spindle assembly;GO:0007018 microtubule-based movement;GO:0032465 regulation of cytokinesis;GO:0001578 microtubule bundle formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LR41-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LR55-1", "uniprot_id": [ { "id": "A0A8C2LR55_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LR55", "type": "external" } ], "mass": 45200.0, "length": 422, "protein_name": "Hemojuvelin", "gene_name": "LOC100756322", "organism": "Hamster", "refseq_name": "hemojuvelin", "refseq_ac": [ { "id": "XP_035307729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307729", "type": "external" } ], "gene_names_uniprotkb": "LOC100756322", "gene_names_refseq": "LOC100756322", "protein_names_uniprotkb": "Hemojuvelin; Hemochromatosis type 2 protein homolog; Hemojuvelin BMP coreceptor; RGM domain family member C", "protein_names_refseq": "hemojuvelin", "tax_id": 10029, "disease": "", "pathway": " (cge:100756322)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015026 coreceptor activity;GO:0098821 BMP receptor activity;GO:0036122 BMP binding;GO:1990459 transferrin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:1990712 HFE-transferrin receptor complex;GO:0070724 BMP receptor complex;GO:0098552 side of membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006879 intracellular iron ion homeostasis;GO:0032924 activin receptor signaling pathway;GO:0016540 protein autoprocessing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LR55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LRG3-1", "uniprot_id": [ { "id": "A0A8C2LRG3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LRG3", "type": "external" } ], "mass": 43326.0, "length": 401, "protein_name": "hypoxia-inducible factor-proline dioxygenase", "gene_name": "Egln1", "organism": "Hamster", "refseq_name": "egl nine homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_007651724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651724", "type": "external" } ], "gene_names_uniprotkb": "Egln1", "gene_names_refseq": "Egln1", "protein_names_uniprotkb": "hypoxia-inducible factor-proline dioxygenase; 1.14.11.29", "protein_names_refseq": "egl nine homolog 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772704)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 554 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613636.1) and transcript sequence (IACG01062242.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651724.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.29", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.29", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008198 ferrous iron binding;GO:0031418 L-ascorbic acid binding;GO:0160082 hypoxia-inducible factor-proline dioxygenase activity;GO:0031545 peptidyl-proline 4-dioxygenase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0005737 cytoplasm", "go_biological_process": "GO:1902072 negative regulation of hypoxia-inducible factor-1alpha signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006879 intracellular iron ion homeostasis;GO:0071456 cellular response to hypoxia;GO:0045765 regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LRG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LRH7-1", "uniprot_id": [ { "id": "A0A8C2LRH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LRH7", "type": "external" } ], "mass": 75066.0, "length": 664, "protein_name": "Semaphorin-7A", "gene_name": "Sema7a", "organism": "Hamster", "refseq_name": "semaphorin-7A isoform X2", "refseq_ac": [ { "id": "XP_027270743", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270743", "type": "external" } ], "gene_names_uniprotkb": "Sema7a", "gene_names_refseq": "Sema7a", "protein_names_uniprotkb": "Semaphorin-7A; Semaphorin-K1; Semaphorin-L", "protein_names_refseq": "semaphorin-7A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756433)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0009897 external side of plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0006954 inflammatory response;GO:0007229 integrin-mediated signaling pathway;GO:0030335 positive regulation of cell migration;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0071526 semaphorin-plexin signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LRH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LRT3-1", "uniprot_id": [ { "id": "A0A8C2LRT3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LRT3", "type": "external" } ], "mass": 154380.0, "length": 1379, "protein_name": "mitogen-activated protein kinase kinase kinase", "gene_name": "Map3k5", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase 5 isoform X2", "refseq_ac": [ { "id": "XP_027257736", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257736", "type": "external" } ], "gene_names_uniprotkb": "Map3k5", "gene_names_refseq": "Map3k5", "protein_names_uniprotkb": "mitogen-activated protein kinase kinase kinase; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752376)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:1990604 IRE1-TRAF2-ASK1 complex;GO:0005829 cytosol;GO:1902911 protein kinase complex", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0046330 positive regulation of JNK cascade;GO:0007254 JNK cascade;GO:0045893 positive regulation of DNA-templated transcription;GO:0070301 cellular response to hydrogen peroxide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LRT3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LRT6-1", "uniprot_id": [ { "id": "A0A8C2LRT6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LRT6", "type": "external" } ], "mass": 42609.0, "length": 380, "protein_name": "Flap endonuclease 1", "gene_name": "Fen1", "organism": "Hamster", "refseq_name": "flap endonuclease 1 isoform X1", "refseq_ac": [ { "id": "XP_007651987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651987", "type": "external" } ], "gene_names_uniprotkb": "Fen1", "gene_names_refseq": "Fen1", "protein_names_uniprotkb": "Flap endonuclease 1; 3.1.-.-; FEN-1; Flap structure-specific endonuclease 1", "protein_names_refseq": "flap endonuclease 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756103)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615987.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003677 DNA binding;GO:0030145 manganese ion binding;GO:0004523 RNA-DNA hybrid ribonuclease activity;GO:0008409 5'-3' exonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0032991 protein-containing complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006284 base-excision repair;GO:0043137 DNA replication, removal of RNA primer;GO:0045876 positive regulation of sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LRT6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LRY8-1", "uniprot_id": [ { "id": "A0A8C2LRY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LRY8", "type": "external" } ], "mass": 182253.0, "length": 1588, "protein_name": "RB1-inducible coiled-coil protein 1", "gene_name": "Rb1cc1", "organism": "Hamster", "refseq_name": "RB1-inducible coiled-coil protein 1 isoform X1", "refseq_ac": [ { "id": "XP_027254741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254741", "type": "external" } ], "gene_names_uniprotkb": "Rb1cc1", "gene_names_refseq": "Rb1cc1", "protein_names_uniprotkb": "RB1-inducible coiled-coil protein 1; FAK family kinase-interacting protein of 200 kDa", "protein_names_refseq": "RB1-inducible coiled-coil protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763340)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways. Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway through induction of RB1 expression. Plays a crucial role in muscular differentiation. Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005764 lysosome;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0010508 positive regulation of autophagy;GO:0000422 autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LRY8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FF76-1", "uniprot_id": [ { "id": "A0A9J7FF76_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FF76", "type": "external" } ], "mass": 26468.0, "length": 239, "protein_name": "Adenylate kinase 2, mitochondrial", "gene_name": "Ak2", "organism": "Hamster", "refseq_name": "adenylate kinase 2, mitochondrial isoform X3", "refseq_ac": [ { "id": "XP_027255160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255160", "type": "external" } ], "gene_names_uniprotkb": "Ak2; AK2", "gene_names_refseq": "Ak2", "protein_names_uniprotkb": "Adenylate kinase 2, mitochondrial; 2.7.4.3; AK 2; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; Adenylate monophosphate kinase", "protein_names_refseq": "adenylate kinase 2, mitochondrial isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100756723)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.10", "type": "external" }, { "id": "2.7.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.14", "type": "external" }, { "id": "2.7.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.4", "type": "external" } ], "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0097226 sperm mitochondrial sheath;GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006172 ADP biosynthetic process;GO:0046033 AMP metabolic process;GO:0046034 ATP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FF76-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LSF5-1", "uniprot_id": [ { "id": "A0A8C2LSF5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LSF5", "type": "external" } ], "mass": 34037.0, "length": 310, "protein_name": "NAD-dependent protein deacylase sirtuin-5, mitochondrial", "gene_name": "Sirt5", "organism": "Hamster", "refseq_name": "NAD-dependent protein deacylase sirtuin-5, mitochondrial", "refseq_ac": [ { "id": "XP_003497985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497985", "type": "external" } ], "gene_names_uniprotkb": "Sirt5; SIRT5", "gene_names_refseq": "Sirt5", "protein_names_uniprotkb": "NAD-dependent protein deacylase sirtuin-5, mitochondrial; 2.3.1.-; Regulatory protein SIR2 homolog 5; SIR2-like protein 5", "protein_names_refseq": "NAD-dependent protein deacylase sirtuin-5, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100767069)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613670.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as Uox., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0036054 protein-malonyllysine demalonylase activity;GO:0036055 protein-succinyllysine desuccinylase activity;GO:0061697 protein-glutaryllysine deglutarylase activity;GO:0008270 zinc ion binding;GO:0070403 NAD+ binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0010566 regulation of ketone biosynthetic process;GO:2000378 negative regulation of reactive oxygen species metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LSF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LSJ7-1", "uniprot_id": [ { "id": "A0A8C2LSJ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LSJ7", "type": "external" } ], "mass": 62391.0, "length": 568, "protein_name": "Natural resistance-associated macrophage protein 2", "gene_name": "Slc11a2", "organism": "Hamster", "refseq_name": "natural resistance-associated macrophage protein 2", "refseq_ac": [ { "id": "XP_003513591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513591", "type": "external" } ], "gene_names_uniprotkb": "Slc11a2", "gene_names_refseq": "Slc11a2", "protein_names_uniprotkb": "Natural resistance-associated macrophage protein 2", "protein_names_refseq": "natural resistance-associated macrophage protein 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764508)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615996.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046870 cadmium ion binding;GO:0015295 solute:proton symporter activity;GO:0005375 copper ion transmembrane transporter activity;GO:0005384 manganese ion transmembrane transporter activity;GO:0015086 cadmium ion transmembrane transporter activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0045178 basal part of cell;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0010039 response to iron ion;GO:0060586 multicellular organismal-level iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LSJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LSN2-1", "uniprot_id": [ { "id": "A0A8C2LSN2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LSN2", "type": "external" } ], "mass": 249800.0, "length": 2208, "protein_name": "Protein unc-13 homolog C", "gene_name": "Unc13c", "organism": "Hamster", "refseq_name": "protein unc-13 homolog C isoform X2", "refseq_ac": [ { "id": "XP_035300372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300372", "type": "external" } ], "gene_names_uniprotkb": "Unc13c", "gene_names_refseq": "Unc13c", "protein_names_uniprotkb": "Protein unc-13 homolog C; Munc13-3", "protein_names_refseq": "protein unc-13 homolog C isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754632)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005543 phospholipid binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0019992 diacylglycerol binding", "go_cellular_component": "GO:0098831 presynaptic active zone cytoplasmic component;GO:0044305 calyx of Held;GO:0031594 neuromuscular junction;GO:0043195 terminal bouton;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0035249 synaptic transmission, glutamatergic;GO:0031914 negative regulation of synaptic plasticity;GO:0016082 synaptic vesicle priming;GO:0099525 presynaptic dense core vesicle exocytosis;GO:0016081 synaptic vesicle docking", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LSN2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LVB9-1", "uniprot_id": [ { "id": "A0A8C2LVB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LVB9", "type": "external" } ], "mass": 23333.0, "length": 205, "protein_name": "JNK pathway associated phosphatase", "gene_name": "Dusp22", "organism": "Hamster", "refseq_name": "dual specificity protein phosphatase 22 isoform X2", "refseq_ac": [ { "id": "XP_027265103", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265103", "type": "external" } ], "gene_names_uniprotkb": "Dusp22", "gene_names_refseq": "Dusp22", "protein_names_uniprotkb": "JNK pathway associated phosphatase; 3.1.3.16; 3.1.3.48; Low molecular weight dual specificity phosphatase 2", "protein_names_refseq": "dual specificity protein phosphatase 22 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759286)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Activates the JNK signaling pathway. Inhibits T-cell receptor signaling and T-cell mediated immune responses, acting, at least in part, by inducing degradation of E3 ubiquitin ligase UBR2. Dephosphorylates and thereby induces 'Lys-48'-linked ubiquitination of UBR2, leading to proteasomal degradation of UBR2. Dephosphorylates and thereby inactivates tyrosine kinase LCK. Inhibits UBR2-mediated 'Lys-63'-linked ubiquitination of LCK. May play a role in B-cell receptor (BCR) signaling and B-cell function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:1990782 protein tyrosine kinase binding;GO:0004725 protein tyrosine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0030292 protein tyrosine kinase inhibitor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0061851 leading edge of lamellipodium;GO:0031941 filamentous actin", "go_biological_process": "GO:0007162 negative regulation of cell adhesion;GO:0007165 signal transduction;GO:0071363 cellular response to growth factor stimulus;GO:0050860 negative regulation of T cell receptor signaling pathway;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LVB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LSS6-1", "uniprot_id": [ { "id": "A0A8C2LSS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LSS6", "type": "external" } ], "mass": 20687.0, "length": 187, "protein_name": "Corticoliberin", "gene_name": "LOC113833763", "organism": "Hamster", "refseq_name": "corticoliberin", "refseq_ac": [ { "id": "XP_027254504", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254504", "type": "external" } ], "gene_names_uniprotkb": "LOC113833763", "gene_names_refseq": "LOC113833763", "protein_names_uniprotkb": "Corticoliberin; Corticotropin-releasing factor; Corticotropin-releasing hormone", "protein_names_refseq": "corticoliberin", "tax_id": 10029, "disease": "", "pathway": " (cge:113833763)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017045 corticotropin-releasing hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043025 neuronal cell body;GO:0045202 synapse", "go_biological_process": "GO:0006954 inflammatory response;GO:0001963 synaptic transmission, dopaminergic;GO:0007565 female pregnancy;GO:0032811 negative regulation of epinephrine secretion;GO:0051461 positive regulation of corticotropin secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LSS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LTL3-1", "uniprot_id": [ { "id": "A0A8C2LTL3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LTL3", "type": "external" } ], "mass": 49658.0, "length": 447, "protein_name": "Neuronal acetylcholine receptor subunit alpha-10", "gene_name": "Chrna10", "organism": "Hamster", "refseq_name": "neuronal acetylcholine receptor subunit alpha-10", "refseq_ac": [ { "id": "XP_027263664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263664", "type": "external" } ], "gene_names_uniprotkb": "Chrna10", "gene_names_refseq": "Chrna10", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha-10", "protein_names_refseq": "neuronal acetylcholine receptor subunit alpha-10", "tax_id": 10029, "disease": "", "pathway": " (cge:100760224)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005262 calcium channel activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity", "go_cellular_component": "GO:0005892 acetylcholine-gated channel complex;GO:0045211 postsynaptic membrane;GO:0098981 cholinergic synapse", "go_biological_process": "GO:0095500 acetylcholine receptor signaling pathway;GO:0051899 membrane depolarization;GO:0010996 response to auditory stimulus;GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LTL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LTZ8-1", "uniprot_id": [ { "id": "A0A8C2LTZ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LTZ8", "type": "external" } ], "mass": 63752.0, "length": 572, "protein_name": "Frizzled-7 isoform X2", "gene_name": "Fzd7", "organism": "Hamster", "refseq_name": "frizzled-7 isoform X1", "refseq_ac": [ { "id": "XP_003497466", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497466", "type": "external" } ], "gene_names_uniprotkb": "Fzd7", "gene_names_refseq": "Fzd7", "protein_names_uniprotkb": "Frizzled-7 isoform X2", "protein_names_refseq": "frizzled-7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 559 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613648.1) and transcript sequence (IACG01077614.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003497466.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005109 frizzled binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0030165 PDZ domain binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0045893 positive regulation of DNA-templated transcription;GO:0019827 stem cell population maintenance;GO:0042327 positive regulation of phosphorylation;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LTZ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LU67-1", "uniprot_id": [ { "id": "A0A8C2LU67_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LU67", "type": "external" } ], "mass": 31651.0, "length": 314, "protein_name": "Paired mesoderm homeobox protein 2B isoform X2", "gene_name": "LOC100751707", "organism": "Hamster", "refseq_name": "paired mesoderm homeobox protein 2B isoform X2", "refseq_ac": [ { "id": "XP_027246489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246489", "type": "external" } ], "gene_names_uniprotkb": "LOC100751707", "gene_names_refseq": "LOC100751707", "protein_names_uniprotkb": "Paired mesoderm homeobox protein 2B isoform X2", "protein_names_refseq": "paired mesoderm homeobox protein 2B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751707)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0003360 brainstem development;GO:0048484 enteric nervous system development;GO:0021723 medullary reticular formation development;GO:0048486 parasympathetic nervous system development;GO:0061452 retrotrapezoid nucleus neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LU67-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LUJ2-1", "uniprot_id": [ { "id": "A0A8C2LUJ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LUJ2", "type": "external" } ], "mass": 35913.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC100772354", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase-like isoform X2", "refseq_ac": [ { "id": "XP_035302496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302496", "type": "external" } ], "gene_names_uniprotkb": "LOC100772354", "gene_names_refseq": "LOC100772354", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772354)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. 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This record is derived from a genomic sequence (NW_003613805.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005504 fatty acid binding;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0010008 endosome membrane;GO:0030139 endocytic vesicle;GO:0060170 ciliary membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0043066 negative regulation of apoptotic process;GO:0050872 white fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LVH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LVK6-1", "uniprot_id": [ { "id": "A0A8C2LVK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LVK6", "type": "external" } ], "mass": 101854.0, "length": 917, "protein_name": "Thyroid peroxidase", "gene_name": "Tpo", "organism": "Hamster", "refseq_name": "thyroid peroxidase", "refseq_ac": [ { "id": "XP_035303925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303925", "type": "external" } ], "gene_names_uniprotkb": "Tpo", "gene_names_refseq": "Tpo", "protein_names_uniprotkb": "Thyroid peroxidase; 1.11.1.8", "protein_names_refseq": "thyroid peroxidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100774668)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.8", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0020037 heme binding;GO:0004447 iodide peroxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0035162 embryonic hemopoiesis;GO:0006979 response to oxidative stress;GO:0042446 hormone biosynthetic process;GO:0042744 hydrogen peroxide catabolic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LVK6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LVM9-1", "uniprot_id": [ { "id": "A0A8C2LVM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LVM9", "type": "external" } ], "mass": 86741.0, "length": 790, "protein_name": "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "gene_name": "Pnpt1", "organism": "Hamster", "refseq_name": "polyribonucleotide nucleotidyltransferase 1, mitochondrial", "refseq_ac": [ { "id": "XP_027243776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243776", "type": "external" } ], "gene_names_uniprotkb": "Pnpt1", "gene_names_refseq": "Pnpt1", "protein_names_uniprotkb": "Polyribonucleotide nucleotidyltransferase 1, mitochondrial; 2.7.7.8; Polynucleotide phosphorylase 1", "protein_names_refseq": "polyribonucleotide nucleotidyltransferase 1, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100766803)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0035198 miRNA binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0004654 polyribonucleotide nucleotidyltransferase activity;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0045025 mitochondrial degradosome", "go_biological_process": "GO:0043457 regulation of cellular respiration;GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process;GO:0000964 mitochondrial RNA 5'-end processing;GO:0006397 mRNA processing;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LVM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFR7-1", "uniprot_id": [ { "id": "A0A8C2QFR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFR7", "type": "external" } ], "mass": 81714.0, "length": 735, "protein_name": "Serine/threonine-protein kinase BRSK2 isoform X2", "gene_name": "Brsk2", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase BRSK2 isoform X2", "refseq_ac": [ { "id": "XP_035297162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297162", "type": "external" } ], "gene_names_uniprotkb": "Brsk2", "gene_names_refseq": "Brsk2", "protein_names_uniprotkb": "Serine/threonine-protein kinase BRSK2 isoform X2", "protein_names_refseq": "serine/threonine-protein kinase BRSK2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769140)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0050321 tau-protein kinase activity;GO:0000287 magnesium ion binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007399 nervous system development;GO:0035556 intracellular signal transduction;GO:0050770 regulation of axonogenesis;GO:0007409 axonogenesis;GO:0000086 G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LVX7-1", "uniprot_id": [ { "id": "A0A8C2LVX7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LVX7", "type": "external" } ], "mass": 28945.0, "length": 271, "protein_name": "Aquaporin-2", "gene_name": "Aqp2", "organism": "Hamster", "refseq_name": "aquaporin-2 isoform X2", "refseq_ac": [ { "id": "XP_027252349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252349", "type": "external" } ], "gene_names_uniprotkb": "Aqp2", "gene_names_refseq": "Aqp2", "protein_names_uniprotkb": "Aquaporin-2; ADH water channel; Aquaporin-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct", "protein_names_refseq": "aquaporin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773344)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015168 glycerol transmembrane transporter activity;GO:0015250 water channel activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome;GO:0070062 extracellular exosome", "go_biological_process": "GO:0003091 renal water homeostasis;GO:0007015 actin filament organization;GO:0051289 protein homotetramerization;GO:0071280 cellular response to copper ion;GO:0071288 cellular response to mercury ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LVX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M110-1", "uniprot_id": [ { "id": "A0A8C2M110_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M110", "type": "external" } ], "mass": 201430.0, "length": 1809, "protein_name": "Tuberin", "gene_name": "Tsc2", "organism": "Hamster", "refseq_name": "tuberin isoform X1", "refseq_ac": [ { "id": "XP_003501552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501552", "type": "external" } ], "gene_names_uniprotkb": "Tsc2", "gene_names_refseq": "Tsc2", "protein_names_uniprotkb": "Tuberin; Tuberous sclerosis 2 protein homolog", "protein_names_refseq": "tuberin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755849)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. Within the TSC-TBC complex, TSC2 acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1. Involved in microtubule-mediated protein transport via its ability to regulate mTORC1 signaling. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0042803 protein homodimerization activity;GO:0031267 small GTPase binding;GO:0051879 Hsp90 protein binding;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0033596 TSC1-TSC2 complex;GO:0005634 nucleus;GO:0045202 synapse;GO:0005765 lysosomal membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0016241 regulation of macroautophagy;GO:0032007 negative regulation of TOR signaling;GO:0030178 negative regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M110-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LW91-1", "uniprot_id": [ { "id": "A0A8C2LW91_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LW91", "type": "external" } ], "mass": 54186.0, "length": 467, "protein_name": "ERO1-like protein alpha", "gene_name": "Ero1a", "organism": "Hamster", "refseq_name": "ERO1-like protein alpha isoform X2", "refseq_ac": [ { "id": "XP_027245096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245096", "type": "external" } ], "gene_names_uniprotkb": "Ero1a", "gene_names_refseq": "Ero1a", "protein_names_uniprotkb": "ERO1-like protein alpha; 1.8.3.2; Endoplasmic reticulum oxidoreductase alpha; Oxidoreductin-1-L-alpha", "protein_names_refseq": "ERO1-like protein alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763138)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0015035 protein-disulfide reductase activity;GO:0016972 thiol oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005796 Golgi lumen;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051209 release of sequestered calcium ion into cytosol;GO:0045454 cell redox homeostasis;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LW91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMM9-1", "uniprot_id": [ { "id": "A0A9J7FMM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMM9", "type": "external" } ], "mass": 103187.0, "length": 912, "protein_name": "Ubiquitin-protein ligase E3A", "gene_name": "Ube3a", "organism": "Hamster", "refseq_name": "ubiquitin-protein ligase E3A isoform X1", "refseq_ac": [ { "id": "XP_007649892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649892", "type": "external" } ], "gene_names_uniprotkb": "Ube3a", "gene_names_refseq": "Ube3a", "protein_names_uniprotkb": "Ubiquitin-protein ligase E3A; 2.3.2.26", "protein_names_refseq": "ubiquitin-protein ligase E3A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772382)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615042.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0008021 synaptic vesicle;GO:0000502 proteasome complex;GO:0099524 postsynaptic cytosol", "go_biological_process": "GO:0048731 system development;GO:0048167 regulation of synaptic plasticity;GO:0032570 response to progesterone;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMM9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LWF0-1", "uniprot_id": [ { "id": "A0A8C2LWF0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LWF0", "type": "external" } ], "mass": 47037.0, "length": 434, "protein_name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "gene_name": "Suclg2", "organism": "Hamster", "refseq_name": "succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027284736", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284736", "type": "external" } ], "gene_names_uniprotkb": "Suclg2; SUCLG2", "gene_names_refseq": "Suclg2", "protein_names_uniprotkb": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; 6.2.1.4; G-SCS; GTP-specific succinyl-CoA synthetase subunit beta; GTPSCS; SCS-betaG; Succinyl-CoA synthetase beta-G chain", "protein_names_refseq": "succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752265)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Also able to act as a GTP-specific itaconyl- and malyl-CoA synthetase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.5", "type": "external" }, { "id": "6.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.4", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity;GO:0004776 succinate-CoA ligase (GDP-forming) activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0045244 succinate-CoA ligase complex (GDP-forming)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LWF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F1W8-1", "uniprot_id": [ { "id": "A0A9J7F1W8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F1W8", "type": "external" } ], "mass": 154812.0, "length": 1389, "protein_name": "Hepatocyte growth factor receptor", "gene_name": "Met", "organism": "Hamster", "refseq_name": "hepatocyte growth factor receptor isoform X1", "refseq_ac": [ { "id": "XP_007639696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639696", "type": "external" } ], "gene_names_uniprotkb": "Met", "gene_names_refseq": "Met", "protein_names_uniprotkb": "Hepatocyte growth factor receptor; 2.7.10.1; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; Tyrosine-protein kinase Met", "protein_names_refseq": "hepatocyte growth factor receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751933)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613810.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0019903 protein phosphatase binding;GO:0017154 semaphorin receptor activity;GO:0005008 hepatocyte growth factor receptor activity", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0009925 basal plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:2001028 positive regulation of endothelial cell chemotaxis;GO:0001889 liver development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042593 glucose homeostasis;GO:0050918 positive chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F1W8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LWT2-1", "uniprot_id": [ { "id": "A0A8C2LWT2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LWT2", "type": "external" } ], "mass": 41610.0, "length": 361, "protein_name": "Septin", "gene_name": "Septin2", "organism": "Hamster", "refseq_name": "septin-2 isoform X1", "refseq_ac": [ { "id": "XP_003499309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499309", "type": "external" } ], "gene_names_uniprotkb": "Septin2", "gene_names_refseq": "Septin2", "protein_names_uniprotkb": "Septin", "protein_names_refseq": "septin-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772434)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 110 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613726.1) and transcript sequence (JI880666.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Filament-forming cytoskeletal GTPase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0097227 sperm annulus;GO:0005634 nucleus;GO:0005819 spindle;GO:0009986 cell surface;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0051301 cell division;GO:0007010 cytoskeleton organization;GO:0060271 cilium assembly;GO:0007224 smoothened signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LWT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LWY6-1", "uniprot_id": [ { "id": "A0A8C2LWY6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LWY6", "type": "external" } ], "mass": 104383.0, "length": 952, "protein_name": "Leucine-rich repeat-containing G-protein coupled receptor 4", "gene_name": "Lgr4", "organism": "Hamster", "refseq_name": "leucine-rich repeat-containing G-protein coupled receptor 4 isoform X2", "refseq_ac": [ { "id": "XP_027278094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278094", "type": "external" } ], "gene_names_uniprotkb": "Lgr4", "gene_names_refseq": "Lgr4", "protein_names_uniprotkb": "Leucine-rich repeat-containing G-protein coupled receptor 4", "protein_names_refseq": "leucine-rich repeat-containing G-protein coupled receptor 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007283 spermatogenesis;GO:0008283 cell population proliferation;GO:0046849 bone remodeling;GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LWY6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LX12-1", "uniprot_id": [ { "id": "A0A8C2LX12_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LX12", "type": "external" } ], "mass": 45571.0, "length": 414, "protein_name": "COUP transcription factor 2 isoform X2", "gene_name": "Nr2f2", "organism": "Hamster", "refseq_name": "COUP transcription factor 2 isoform X2", "refseq_ac": [ { "id": "XP_027263935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263935", "type": "external" } ], "gene_names_uniprotkb": "Nr2f2", "gene_names_refseq": "Nr2f2", "protein_names_uniprotkb": "COUP transcription factor 2 isoform X2", "protein_names_refseq": "COUP transcription factor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754351)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060838 lymphatic endothelial cell fate commitment;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0008585 female gonad development;GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LX12-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LXP3-1", "uniprot_id": [ { "id": "A0A8C2LXP3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LXP3", "type": "external" } ], "mass": 16485.0, "length": 145, "protein_name": "Phospholipase A2", "gene_name": "Pla2g2d", "organism": "Hamster", "refseq_name": "group IID secretory phospholipase A2", "refseq_ac": [ { "id": "XP_003506946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506946", "type": "external" } ], "gene_names_uniprotkb": "Pla2g2d", "gene_names_refseq": "Pla2g2d", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "group IID secretory phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754712)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614302.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008201 heparin binding;GO:0043395 heparan sulfate proteoglycan binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0042130 negative regulation of T cell proliferation;GO:0050482 arachidonate secretion;GO:0046470 phosphatidylcholine metabolic process;GO:0046471 phosphatidylglycerol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LXP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LXQ0-1", "uniprot_id": [ { "id": "A0A8C2LXQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LXQ0", "type": "external" } ], "mass": 57455.0, "length": 519, "protein_name": "Major facilitator superfamily domain-containing protein 8 isoform X1", "gene_name": "Mfsd8", "organism": "Hamster", "refseq_name": "major facilitator superfamily domain-containing protein 8 isoform X1", "refseq_ac": [ { "id": "XP_027247734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247734", "type": "external" } ], "gene_names_uniprotkb": "Mfsd8", "gene_names_refseq": "Mfsd8", "protein_names_uniprotkb": "Major facilitator superfamily domain-containing protein 8 isoform X1", "protein_names_refseq": "major facilitator superfamily domain-containing protein 8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771697)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005254 chloride channel activity;GO:0015111 iodide transmembrane transporter activity;GO:0062054 fluoride channel activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LXQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LXQ9-1", "uniprot_id": [ { "id": "A0A8C2LXQ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LXQ9", "type": "external" } ], "mass": 37671.0, "length": 341, "protein_name": "KH domain-containing RNA-binding protein QKI", "gene_name": "Qki", "organism": "Hamster", "refseq_name": "protein quaking isoform X2", "refseq_ac": [ { "id": "XP_027256908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256908", "type": "external" } ], "gene_names_uniprotkb": "Qki", "gene_names_refseq": "Qki", "protein_names_uniprotkb": "KH domain-containing RNA-binding protein QKI; Protein quaking", "protein_names_refseq": "protein quaking isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750964)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0003730 mRNA 3'-UTR binding;GO:0160089 internal N(7)-methylguanine-containing RNA reader activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0045202 synapse;GO:0005634 nucleus", "go_biological_process": "GO:0010717 regulation of epithelial to mesenchymal transition;GO:0035886 vascular associated smooth muscle cell differentiation;GO:0048255 mRNA stabilization;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LXQ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LXT5-1", "uniprot_id": [ { "id": "A0A8C2LXT5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LXT5", "type": "external" } ], "mass": 77801.0, "length": 698, "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "Acsl1", "organism": "Hamster", "refseq_name": "long-chain-fatty-acid--CoA ligase 1 isoform X1", "refseq_ac": [ { "id": "XP_003511518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511518", "type": "external" } ], "gene_names_uniprotkb": "Acsl1", "gene_names_refseq": "Acsl1", "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase; 6.2.1.15; 6.2.1.3; Acyl-CoA synthetase; Long-chain acyl-CoA synthetase", "protein_names_refseq": "long-chain-fatty-acid--CoA ligase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751492)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615125.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0047676 arachidonate-CoA ligase activity;GO:0043539 protein serine/threonine kinase activator activity;GO:0090433 palmitoyl-CoA ligase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0044539 long-chain fatty acid import into cell;GO:0120162 positive regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LXT5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LXW3-1", "uniprot_id": [ { "id": "A0A8C2LXW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LXW3", "type": "external" } ], "mass": 149239.0, "length": 1335, "protein_name": "Regulatory-associated protein of mTOR", "gene_name": "Rptor", "organism": "Hamster", "refseq_name": "regulatory-associated protein of mTOR isoform X1", "refseq_ac": [ { "id": "XP_003496921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496921", "type": "external" } ], "gene_names_uniprotkb": "Rptor", "gene_names_refseq": "Rptor", "protein_names_uniprotkb": "Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein", "protein_names_refseq": "regulatory-associated protein of mTOR isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761529)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity;GO:0044877 protein-containing complex binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0010494 cytoplasmic stress granule;GO:0031931 TORC1 complex;GO:0005764 lysosome", "go_biological_process": "GO:0030307 positive regulation of cell growth;GO:0071333 cellular response to glucose stimulus;GO:0010507 negative regulation of autophagy;GO:0032008 positive regulation of TOR signaling;GO:1900087 positive regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LXW3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LYC0-1", "uniprot_id": [ { "id": "A0A8C2LYC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LYC0", "type": "external" } ], "mass": 177098.0, "length": 1607, "protein_name": "Laminin subunit gamma-1", "gene_name": "Lamc1", "organism": "Hamster", "refseq_name": "laminin subunit gamma-1 isoform X1", "refseq_ac": [ { "id": "XP_003502901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502901", "type": "external" } ], "gene_names_uniprotkb": "Lamc1", "gene_names_refseq": "Lamc1", "protein_names_uniprotkb": "Laminin subunit gamma-1; Laminin B2 chain; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 subunit gamma; S-laminin subunit gamma", "protein_names_refseq": "laminin subunit gamma-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761564)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 620 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613921.1) and transcript sequence (IACG01084872.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003502901.1. COMPLETENESS: full length., [RefSeq]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a subunit of laminin-1 (also known as laminin-111 or EHS laminin), it is involved in the stimulation of agrin-induced receptor clustering through a MuSK-independent pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0043259 laminin-10 complex", "go_biological_process": "GO:0016477 cell migration;GO:0022617 extracellular matrix disassembly;GO:0009887 animal organ morphogenesis;GO:0034446 substrate adhesion-dependent cell spreading;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LYC0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LYP2-1", "uniprot_id": [ { "id": "A0A8C2LYP2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LYP2", "type": "external" } ], "mass": 73851.0, "length": 649, "protein_name": "FAS-associated factor 1", "gene_name": "Faf1", "organism": "Hamster", "refseq_name": "FAS-associated factor 1 isoform X2", "refseq_ac": [ { "id": "XP_003496534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496534", "type": "external" } ], "gene_names_uniprotkb": "Faf1", "gene_names_refseq": "Faf1", "protein_names_uniprotkb": "FAS-associated factor 1", "protein_names_refseq": "FAS-associated factor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774441)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 445 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613624.1) and transcript sequence (IACG01073864.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003496534.2. COMPLETENESS: full length., [RefSeq]; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0031072 heat shock protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0051059 NF-kappaB binding", "go_cellular_component": "GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006915 apoptotic process;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0045732 positive regulation of protein catabolic process;GO:0036503 ERAD pathway;GO:0045740 positive regulation of DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LYP2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LYS8-1", "uniprot_id": [ { "id": "A0A8C2LYS8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LYS8", "type": "external" } ], "mass": 64647.0, "length": 570, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt2", "organism": "Hamster", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 2 isoform X2", "refseq_ac": [ { "id": "XP_027260651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260651", "type": "external" } ], "gene_names_uniprotkb": "Galnt2", "gene_names_refseq": "Galnt2", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "polypeptide N-acetylgalactosaminyltransferase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767525)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0048471 perinuclear region of cytoplasm;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0051604 protein maturation;GO:0002639 positive regulation of immunoglobulin production;GO:0006493 protein O-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LYS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LYT3-1", "uniprot_id": [ { "id": "A0A8C2LYT3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LYT3", "type": "external" } ], "mass": 57565.0, "length": 508, "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "Rbck1", "organism": "Hamster", "refseq_name": "ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027277314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277314", "type": "external" } ], "gene_names_uniprotkb": "Rbck1", "gene_names_refseq": "Rbck1", "protein_names_uniprotkb": "RanBP-type and C3HC4-type zinc finger-containing protein 1; 2.3.2.31; Heme-oxidized IRP2 ubiquitin ligase 1 homolog; RING-type E3 ubiquitin transferase HOIL-1; Ubiquitin-conjugating enzyme 7-interacting protein 3", "protein_names_refseq": "ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761016)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0043130 ubiquitin binding;GO:1990757 ubiquitin ligase activator activity", "go_cellular_component": "GO:0071797 LUBAC complex", "go_biological_process": "GO:0097039 protein linear polyubiquitination;GO:0043065 positive regulation of apoptotic process;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0050852 T cell receptor signaling pathway;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LYT3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M014-1", "uniprot_id": [ { "id": "A0A8C2M014_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M014", "type": "external" } ], "mass": 108078.0, "length": 970, "protein_name": "Sodium/calcium exchanger 1", "gene_name": "Slc8a1", "organism": "Hamster", "refseq_name": "sodium/calcium exchanger 1 isoform X1", "refseq_ac": [ { "id": "XP_035301423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301423", "type": "external" } ], "gene_names_uniprotkb": "Slc8a1", "gene_names_refseq": "Slc8a1", "protein_names_uniprotkb": "Sodium/calcium exchanger 1; Na(+)/Ca(2+)-exchange protein 1; Solute carrier family 8 member 1", "protein_names_refseq": "sodium/calcium exchanger 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760799)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0005432 calcium:sodium antiporter activity;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0030424 axon;GO:0098794 postsynapse;GO:0042383 sarcolemma;GO:0043226 organelle", "go_biological_process": "GO:0007154 cell communication;GO:0055074 calcium ion homeostasis;GO:0098703 calcium ion import across plasma membrane;GO:0006883 intracellular sodium ion homeostasis;GO:0030501 positive regulation of bone mineralization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M014-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LYV3-1", "uniprot_id": [ { "id": "A0A8C2LYV3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LYV3", "type": "external" } ], "mass": 90799.0, "length": 795, "protein_name": "Toll-like receptor 1", "gene_name": "Tlr1", "organism": "Hamster", "refseq_name": "toll-like receptor 1", "refseq_ac": [ { "id": "XP_027246531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246531", "type": "external" } ], "gene_names_uniprotkb": "Tlr1", "gene_names_refseq": "Tlr1", "protein_names_uniprotkb": "Toll-like receptor 1", "protein_names_refseq": "toll-like receptor 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759973)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0042802 identical protein binding;GO:0071723 lipopeptide binding;GO:0035663 Toll-like receptor 2 binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0044853 plasma membrane raft;GO:0030670 phagocytic vesicle membrane;GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0032755 positive regulation of interleukin-6 production;GO:0032760 positive regulation of tumor necrosis factor production;GO:0032757 positive regulation of interleukin-8 production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LYV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LZ72-1", "uniprot_id": [ { "id": "A0A8C2LZ72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LZ72", "type": "external" } ], "mass": 23128.0, "length": 199, "protein_name": "Hematopoietic prostaglandin D synthase", "gene_name": "Hpgds", "organism": "Hamster", "refseq_name": "hematopoietic prostaglandin D synthase", "refseq_ac": [ { "id": "XP_035304958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304958", "type": "external" } ], "gene_names_uniprotkb": "Hpgds", "gene_names_refseq": "Hpgds", "protein_names_uniprotkb": "Hematopoietic prostaglandin D synthase; 2.5.1.18; 5.3.99.2; GST class-sigma; Glutathione S-transferase; Glutathione-dependent PGD synthase; Glutathione-requiring prostaglandin D synthase; Prostaglandin-H2 D-isomerase", "protein_names_refseq": "hematopoietic prostaglandin D synthase", "tax_id": 10029, "disease": "", "pathway": " (cge:100768035)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" } ], "go_molecular_function": "GO:0004667 prostaglandin-D synthase activity;GO:0004364 glutathione transferase activity;GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019371 cyclooxygenase pathway;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LZ72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LZI5-1", "uniprot_id": [ { "id": "A0A8C2LZI5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LZI5", "type": "external" } ], "mass": 15810.0, "length": 142, "protein_name": "Phospholipase A2", "gene_name": "LOC100764593", "organism": "Hamster", "refseq_name": "phospholipase A2", "refseq_ac": [ { "id": "XP_003510845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510845", "type": "external" } ], "gene_names_uniprotkb": "LOC100764593", "gene_names_refseq": "LOC100764593", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764593)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614968.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LZI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M087-1", "uniprot_id": [ { "id": "A0A8C2M087_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M087", "type": "external" } ], "mass": 32688.0, "length": 279, "protein_name": "Elongation of very long chain fatty acids protein 1", "gene_name": "Elovl1", "organism": "Hamster", "refseq_name": "elongation of very long chain fatty acids protein 1 isoform X2", "refseq_ac": [ { "id": "XP_007641479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641479", "type": "external" } ], "gene_names_uniprotkb": "Elovl1; ELOVL1", "gene_names_refseq": "Elovl1", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 1; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1", "protein_names_refseq": "elongation of very long chain fatty acids protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613906.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0061436 establishment of skin barrier;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M087-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M0H3-1", "uniprot_id": [ { "id": "A0A8C2M0H3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M0H3", "type": "external" } ], "mass": 38804.0, "length": 373, "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1", "organism": "Hamster", "refseq_name": "heterogeneous nuclear ribonucleoprotein A1 isoform X1", "refseq_ac": [ { "id": "XP_007652254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652254", "type": "external" } ], "gene_names_uniprotkb": "Hnrnpa1", "gene_names_refseq": "Hnrnpa1", "protein_names_uniprotkb": "Heterogeneous nuclear ribonucleoprotein A1; Helix-destabilizing protein; hnRNP core protein A1", "protein_names_refseq": "heterogeneous nuclear ribonucleoprotein A1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769923)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616167.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and modulation of splice site selection. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform. Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1. May bind to specific miRNA hairpins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0036002 pre-mRNA binding;GO:0098505 G-rich strand telomeric DNA binding;GO:0061752 telomeric repeat-containing RNA binding;GO:0019904 protein domain specific binding;GO:0035198 miRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0045202 synapse;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0051170 import into nucleus;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0032212 positive regulation of telomere maintenance via telomerase;GO:0042149 cellular response to glucose starvation;GO:0051168 nuclear export", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M0H3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M0M7-1", "uniprot_id": [ { "id": "A0A8C2M0M7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M0M7", "type": "external" } ], "mass": 16653.0, "length": 150, "protein_name": "Leukotriene C4 synthase", "gene_name": "LOC113836822", "organism": "Hamster", "refseq_name": "leukotriene C4 synthase", "refseq_ac": [ { "id": "XP_027283448", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283448", "type": "external" } ], "gene_names_uniprotkb": "LOC113836822", "gene_names_refseq": "LOC113836822", "protein_names_uniprotkb": "Leukotriene C4 synthase; 2.5.1.-; 4.4.1.20; Leukotriene-C(4) synthase", "protein_names_refseq": "leukotriene C4 synthase", "tax_id": 10029, "disease": "", "pathway": " (cge:113836822)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004464 leukotriene-C4 synthase activity;GO:0008047 enzyme activator activity;GO:0042802 identical protein binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005640 nuclear outer membrane", "go_biological_process": "GO:0019370 leukotriene biosynthetic process;GO:0042759 long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M0M7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M199-1", "uniprot_id": [ { "id": "A0A8C2M199_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M199", "type": "external" } ], "mass": 141321.0, "length": 1240, "protein_name": "Cohesin subunit SA", "gene_name": "Stag3", "organism": "Hamster", "refseq_name": "cohesin subunit SA-3", "refseq_ac": [ { "id": "XP_007649240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649240", "type": "external" } ], "gene_names_uniprotkb": "Stag3", "gene_names_refseq": "Stag3", "protein_names_uniprotkb": "Cohesin subunit SA; SCC3 homolog; Stromal antigen", "protein_names_refseq": "cohesin subunit SA-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100772292)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, UniProtKB]; Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0030893 meiotic cohesin complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000775 chromosome, centromeric region;GO:0001673 male germ cell nucleus", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0051321 meiotic cell cycle;GO:0034089 establishment of meiotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8C2M199-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M1K6-1", "uniprot_id": [ { "id": "A0A8C2M1K6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M1K6", "type": "external" } ], "mass": 51525.0, "length": 466, "protein_name": "Muscarinic acetylcholine receptor", "gene_name": "Chrm2", "organism": "Hamster", "refseq_name": "muscarinic acetylcholine receptor M2", "refseq_ac": [ { "id": "XP_035307917", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307917", "type": "external" } ], "gene_names_uniprotkb": "Chrm2", "gene_names_refseq": "Chrm2", "protein_names_uniprotkb": "Muscarinic acetylcholine receptor", "protein_names_refseq": "muscarinic acetylcholine receptor M2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770997)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Muscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. CHRM2 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G proteins and mediates signaling by inhibiting adenylate cyclase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016907 G protein-coupled acetylcholine receptor activity;GO:0004993 G protein-coupled serotonin receptor activity;GO:1990763 arrestin family protein binding", "go_cellular_component": "GO:0030425 dendrite;GO:0045211 postsynaptic membrane;GO:0098793 presynapse;GO:0098981 cholinergic synapse", "go_biological_process": "GO:0006940 regulation of smooth muscle contraction;GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008016 regulation of heart contraction;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M1K6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M248-1", "uniprot_id": [ { "id": "A0A8C2M248_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M248", "type": "external" } ], "mass": 79356.0, "length": 712, "protein_name": "Frizzled-6", "gene_name": "Fzd6", "organism": "Hamster", "refseq_name": "frizzled-6 isoform X2", "refseq_ac": [ { "id": "XP_035305578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305578", "type": "external" } ], "gene_names_uniprotkb": "Fzd6", "gene_names_refseq": "Fzd6", "protein_names_uniprotkb": "Frizzled-6", "protein_names_refseq": "frizzled-6 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774509)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0031625 ubiquitin protein ligase binding;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0016327 apicolateral plasma membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042472 inner ear morphogenesis;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0001942 hair follicle development;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M248-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M292-1", "uniprot_id": [ { "id": "A0A8C2M292_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M292", "type": "external" } ], "mass": 96305.0, "length": 873, "protein_name": "Very low-density lipoprotein receptor", "gene_name": "LOC100767645", "organism": "Hamster", "refseq_name": "very low-density lipoprotein receptor isoform X4", "refseq_ac": [ { "id": "XP_035297790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297790", "type": "external" } ], "gene_names_uniprotkb": "LOC100767645", "gene_names_refseq": "LOC100767645", "protein_names_uniprotkb": "Very low-density lipoprotein receptor", "protein_names_refseq": "very low-density lipoprotein receptor isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100767645)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0034185 apolipoprotein binding;GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding;GO:0042562 hormone binding;GO:0001618 virus receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005905 clathrin-coated pit;GO:0043235 receptor complex;GO:0016324 apical plasma membrane;GO:0034361 very-low-density lipoprotein particle", "go_biological_process": "GO:0006869 lipid transport;GO:0008203 cholesterol metabolic process;GO:0034436 glycoprotein transport;GO:0006898 receptor-mediated endocytosis;GO:0051963 regulation of synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M292-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M2J6-1", "uniprot_id": [ { "id": "A0A8C2M2J6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M2J6", "type": "external" } ], "mass": 100561.0, "length": 921, "protein_name": "Sodium/calcium exchanger 2 isoform X2", "gene_name": "Slc8a2", "organism": "Hamster", "refseq_name": "sodium/calcium exchanger 2 isoform X2", "refseq_ac": [ { "id": "XP_035305383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305383", "type": "external" } ], "gene_names_uniprotkb": "Slc8a2", "gene_names_refseq": "Slc8a2", "protein_names_uniprotkb": "Sodium/calcium exchanger 2 isoform X2", "protein_names_refseq": "sodium/calcium exchanger 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765653)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0005432 calcium:sodium antiporter activity", "go_cellular_component": "GO:0014069 postsynaptic density;GO:0043679 axon terminus;GO:0042383 sarcolemma;GO:0030424 axon;GO:0098794 postsynapse", "go_biological_process": "GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0007612 learning;GO:0007613 memory;GO:0070050 neuron cellular homeostasis;GO:0006874 intracellular calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M2J6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M2L0-1", "uniprot_id": [ { "id": "A0A8C2M2L0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M2L0", "type": "external" } ], "mass": 50464.0, "length": 440, "protein_name": "Glycerophosphocholine cholinephosphodiesterase ENPP6", "gene_name": "Enpp6", "organism": "Hamster", "refseq_name": "glycerophosphocholine cholinephosphodiesterase ENPP6", "refseq_ac": [ { "id": "XP_003495528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495528", "type": "external" } ], "gene_names_uniprotkb": "Enpp6", "gene_names_refseq": "Enpp6", "protein_names_uniprotkb": "Glycerophosphocholine cholinephosphodiesterase ENPP6; 3.1.4.38; Choline-specific glycerophosphodiester phosphodiesterase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6", "protein_names_refseq": "glycerophosphocholine cholinephosphodiesterase ENPP6", "tax_id": 10029, "disease": "", "pathway": " (cge:100757074)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613593.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.38", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.38", "type": "external" }, { "id": "3.1.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.12", "type": "external" } ], "go_molecular_function": "GO:0047390 glycerophosphocholine cholinephosphodiesterase activity;GO:0046872 metal ion binding;GO:0008889 glycerophosphodiester phosphodiesterase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0019695 choline metabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M2L0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M2M6-1", "uniprot_id": [ { "id": "A0A8C2M2M6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M2M6", "type": "external" } ], "mass": 225591.0, "length": 2032, "protein_name": "Cytoskeleton-associated protein 5", "gene_name": "Ckap5", "organism": "Hamster", "refseq_name": "cytoskeleton-associated protein 5 isoform X1", "refseq_ac": [ { "id": "XP_003497349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497349", "type": "external" } ], "gene_names_uniprotkb": "Ckap5", "gene_names_refseq": "Ckap5", "protein_names_uniprotkb": "Cytoskeleton-associated protein 5", "protein_names_refseq": "cytoskeleton-associated protein 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755237)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613646.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as a processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:0051010 microtubule plus-end binding;GO:0061863 microtubule plus end polymerase", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0000776 kinetochore;GO:0032991 protein-containing complex", "go_biological_process": "GO:0046785 microtubule polymerization;GO:0051301 cell division;GO:0007098 centrosome cycle;GO:0007051 spindle organization;GO:0090063 positive regulation of microtubule nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M2M6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M332-1", "uniprot_id": [ { "id": "A0A8C2M332_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M332", "type": "external" } ], "mass": 23612.0, "length": 215, "protein_name": "Heart- and neural crest derivatives-expressed protein 1", "gene_name": "Hand1", "organism": "Hamster", "refseq_name": "heart- and neural crest derivatives-expressed protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027282008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282008", "type": "external" } ], "gene_names_uniprotkb": "Hand1", "gene_names_refseq": "Hand1", "protein_names_uniprotkb": "Heart- and neural crest derivatives-expressed protein 1", "protein_names_refseq": "heart- and neural crest derivatives-expressed protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767952)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box). Acts as a transcriptional repressor of SOX15. In the adult, could be required for ongoing expression of cardiac-specific genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0001829 trophectodermal cell differentiation;GO:0003218 cardiac left ventricle formation;GO:0003219 cardiac right ventricle formation;GO:0060411 cardiac septum morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M332-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M375-1", "uniprot_id": [ { "id": "A0A8C2M375_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M375", "type": "external" } ], "mass": 46366.0, "length": 415, "protein_name": "Vascular endothelial growth factor C", "gene_name": "Vegfc", "organism": "Hamster", "refseq_name": "vascular endothelial growth factor C isoform X1", "refseq_ac": [ { "id": "XP_027246845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246845", "type": "external" } ], "gene_names_uniprotkb": "Vegfc", "gene_names_refseq": "Vegfc", "protein_names_uniprotkb": "Vascular endothelial growth factor C; Flt4 ligand; Vascular endothelial growth factor-related protein", "protein_names_refseq": "vascular endothelial growth factor C isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753419)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043185 vascular endothelial growth factor receptor 3 binding;GO:0042056 chemoattractant activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0001666 response to hypoxia;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation;GO:0051781 positive regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M375-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M3E8-1", "uniprot_id": [ { "id": "A0A8C2M3E8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M3E8", "type": "external" } ], "mass": 89404.0, "length": 825, "protein_name": "Protein kintoun", "gene_name": "Dnaaf2", "organism": "Hamster", "refseq_name": "protein kintoun isoform X2", "refseq_ac": [ { "id": "XP_027273947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273947", "type": "external" } ], "gene_names_uniprotkb": "Dnaaf2; DNAAF2; KTU", "gene_names_refseq": "Dnaaf2", "protein_names_uniprotkb": "Protein kintoun; Dynein assembly factor 2, axonemal", "protein_names_refseq": "protein kintoun isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753981)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005829 cytosol;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0003351 epithelial cilium movement involved in extracellular fluid movement;GO:0060285 cilium-dependent cell motility;GO:0070286 axonemal dynein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M3E8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M3I0-1", "uniprot_id": [ { "id": "A0A8C2M3I0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M3I0", "type": "external" } ], "mass": 31434.0, "length": 278, "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase", "gene_name": "Agpat2", "organism": "Hamster", "refseq_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1", "refseq_ac": [ { "id": "XP_003514969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514969", "type": "external" } ], "gene_names_uniprotkb": "Agpat2", "gene_names_refseq": "Agpat2", "protein_names_uniprotkb": "1-acyl-sn-glycerol-3-phosphate acyltransferase; 2.3.1.51", "protein_names_refseq": "1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754963)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 436 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617120.1) and transcript sequence (IACG01044798.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003514969.2. COMPLETENESS: full length., [RefSeq]; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0001819 positive regulation of cytokine production;GO:0019432 triglyceride biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M3I0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M3I3-1", "uniprot_id": [ { "id": "A0A8C2M3I3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M3I3", "type": "external" } ], "mass": 57912.0, "length": 548, "protein_name": "LIM domain-containing protein ajuba isoform X2", "gene_name": "Ajuba", "organism": "Hamster", "refseq_name": "LIM domain-containing protein ajuba isoform X1", "refseq_ac": [ { "id": "XP_007644770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644770", "type": "external" } ], "gene_names_uniprotkb": "Ajuba", "gene_names_refseq": "Ajuba", "protein_names_uniprotkb": "LIM domain-containing protein ajuba isoform X2", "protein_names_refseq": "LIM domain-containing protein ajuba isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103158564)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases assembly gap :: added 485 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614213.1) and transcript sequence (IACG01081287.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007644770.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:0051015 actin filament binding;GO:0003714 transcription corepressor activity;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005912 adherens junction;GO:0005925 focal adhesion;GO:0030027 lamellipodium", "go_biological_process": "GO:0001666 response to hypoxia;GO:0007010 cytoskeleton organization;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0035331 negative regulation of hippo signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M3I3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M3M6-1", "uniprot_id": [ { "id": "A0A8C2M3M6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M3M6", "type": "external" } ], "mass": 346913.0, "length": 3293, "protein_name": "Protocadherin-16", "gene_name": "Dchs1", "organism": "Hamster", "refseq_name": "protocadherin-16 isoform X2", "refseq_ac": [ { "id": "XP_035298190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298190", "type": "external" } ], "gene_names_uniprotkb": "Dchs1", "gene_names_refseq": "Dchs1", "protein_names_uniprotkb": "Protocadherin-16; Protein dachsous homolog 1", "protein_names_refseq": "protocadherin-16 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760642)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0045177 apical part of cell;GO:0016342 catenin complex", "go_biological_process": "GO:0043931 ossification involved in bone maturation;GO:0072137 condensed mesenchymal cell proliferation;GO:0003192 mitral valve formation;GO:0035329 hippo signaling;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M3M6-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M3U9-1", "uniprot_id": [ { "id": "A0A8C2M3U9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M3U9", "type": "external" } ], "mass": 33127.0, "length": 286, "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3", "gene_name": "Alkbh3", "organism": "Hamster", "refseq_name": "alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1", "refseq_ac": [ { "id": "XP_003507815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507815", "type": "external" } ], "gene_names_uniprotkb": "Alkbh3", "gene_names_refseq": "Alkbh3", "protein_names_uniprotkb": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; 1.14.11.33; 1.14.11.54; Alkylated DNA repair protein alkB homolog 3", "protein_names_refseq": "alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774403)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614421.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Can repair exocyclic 3,N4-ethenocytosine adducs in single-stranded DNA. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons. Requires molecular oxygen, alpha-ketoglutarate and iron., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.33", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.33", "type": "external" }, { "id": "1.14.11.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.54", "type": "external" }, { "id": "1.14.11.51", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.51", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" } ], "go_molecular_function": "GO:0008198 ferrous iron binding;GO:1990930 mRNA N1-methyladenosine dioxygenase activity;GO:0035516 broad specificity oxidative DNA demethylase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0008283 cell population proliferation;GO:0006307 DNA alkylation repair;GO:2000766 negative regulation of cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M3U9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M443-1", "uniprot_id": [ { "id": "A0A8C2M443_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M443", "type": "external" } ], "mass": 165597.0, "length": 1477, "protein_name": "Coiled-coil domain-containing protein 88B", "gene_name": "Ccdc88b", "organism": "Hamster", "refseq_name": "coiled-coil domain-containing protein 88B", "refseq_ac": [ { "id": "XP_027264261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264261", "type": "external" } ], "gene_names_uniprotkb": "Ccdc88b", "gene_names_refseq": "Ccdc88b", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 88B; Gipie; Hook-related protein 3", "protein_names_refseq": "coiled-coil domain-containing protein 88B", "tax_id": 10029, "disease": "", "pathway": " (cge:100774835)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0051959 dynein light intermediate chain binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0001819 positive regulation of cytokine production;GO:0042102 positive regulation of T cell proliferation;GO:0042832 defense response to protozoan;GO:0030705 cytoskeleton-dependent intracellular transport;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M443-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M444-1", "uniprot_id": [ { "id": "A0A8C2M444_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M444", "type": "external" } ], "mass": 54292.0, "length": 481, "protein_name": "Guanine nucleotide exchange C9orf72 homolog isoform X1", "gene_name": "C9orf72", "organism": "Hamster", "refseq_name": "guanine nucleotide exchange C9orf72 homolog isoform X1", "refseq_ac": [ { "id": "XP_027259186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259186", "type": "external" } ], "gene_names_uniprotkb": "C9orf72", "gene_names_refseq": "C9orf72", "protein_names_uniprotkb": "Guanine nucleotide exchange C9orf72 homolog isoform X1", "protein_names_refseq": "guanine nucleotide exchange C9orf72 homolog isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764363)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005768 endosome;GO:0043204 perikaryon", "go_biological_process": "GO:0006897 endocytosis;GO:0032880 regulation of protein localization;GO:0016239 positive regulation of macroautophagy;GO:0034063 stress granule assembly;GO:0048675 axon extension", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M444-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M472-1", "uniprot_id": [ { "id": "A0A8C2M472_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M472", "type": "external" } ], "mass": 26175.0, "length": 246, "protein_name": "Mesoderm posterior protein 1-like", "gene_name": "LOC113834924", "organism": "Hamster", "refseq_name": "mesoderm posterior protein 1-like", "refseq_ac": [ { "id": "XP_027264019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264019", "type": "external" } ], "gene_names_uniprotkb": "LOC113834924", "gene_names_refseq": "LOC113834924", "protein_names_uniprotkb": "Mesoderm posterior protein 1-like", "protein_names_refseq": "mesoderm posterior protein 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113834924)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0060913 cardiac cell fate determination;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M472-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M497-1", "uniprot_id": [ { "id": "A0A8C2M497_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M497", "type": "external" } ], "mass": 77852.0, "length": 683, "protein_name": "Protein kinase C eta type", "gene_name": "Prkch", "organism": "Hamster", "refseq_name": "protein kinase C eta type isoform X2", "refseq_ac": [ { "id": "XP_027274046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274046", "type": "external" } ], "gene_names_uniprotkb": "Prkch", "gene_names_refseq": "Prkch", "protein_names_uniprotkb": "Protein kinase C eta type; 2.7.11.13; PKC-L; nPKC-eta", "protein_names_refseq": "protein kinase C eta type isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751001)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation. In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement. Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs. In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation. Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1. Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation. In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": 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This record is derived from a genomic sequence (NW_003614604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity;GO:0030552 cAMP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0006198 cAMP catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M819-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M4P9-1", "uniprot_id": [ { "id": "A0A8C2M4P9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M4P9", "type": "external" } ], "mass": 67939.0, "length": 628, "protein_name": "dual-specificity kinase", "gene_name": "Tesk1", "organism": "Hamster", "refseq_name": "dual specificity testis-specific protein kinase 1 isoform X2", "refseq_ac": [ { "id": "XP_027259051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259051", "type": "external" } ], "gene_names_uniprotkb": "Tesk1", "gene_names_refseq": "Tesk1", "protein_names_uniprotkb": "dual-specificity kinase; 2.7.12.1", "protein_names_refseq": "dual specificity testis-specific protein kinase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756840)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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"4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0030036 actin cytoskeleton organization;GO:0051496 positive regulation of stress fiber assembly;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading;GO:0090521 podocyte cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M4P9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M505-1", "uniprot_id": [ { "id": 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0046982 protein heterodimerization activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0033081 regulation of T cell differentiation in thymus;GO:0006357 regulation of transcription by RNA polymerase II;GO:0042110 T cell activation;GO:0042552 myelination;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M505-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M5Z9-1", "uniprot_id": [ { "id": "A0A8C2M5Z9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M5Z9", "type": "external" } ], "mass": 72777.0, "length": 637, "protein_name": "Protein arginine N-methyltransferase 5", "gene_name": "Prmt5", "organism": "Hamster", "refseq_name": "protein arginine N-methyltransferase 5", "refseq_ac": [ { "id": "XP_027246444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246444", "type": "external" } ], "gene_names_uniprotkb": "Prmt5", "gene_names_refseq": "Prmt5", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 5; 2.1.1.320", "protein_names_refseq": "protein arginine N-methyltransferase 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100768836)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.320", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.320", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0043021 ribonucleoprotein complex binding;GO:0046982 protein heterodimerization activity;GO:0008327 methyl-CpG binding;GO:0044020 histone H4R3 methyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0000785 chromatin;GO:0034709 methylosome;GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0042118 endothelial cell activation;GO:0000387 spliceosomal snRNP assembly;GO:0006353 DNA-templated transcription termination;GO:0090161 Golgi ribbon formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M5Z9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M8A5-1", "uniprot_id": [ { "id": "A0A8C2M8A5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M8A5", "type": "external" } ], "mass": 27299.0, "length": 245, "protein_name": "Paired mesoderm homeobox protein 1 isoform X2", "gene_name": "Prrx1", "organism": "Hamster", "refseq_name": "paired mesoderm homeobox protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027272989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272989", "type": "external" } ], "gene_names_uniprotkb": "Prrx1", "gene_names_refseq": "Prrx1", "protein_names_uniprotkb": "Paired mesoderm homeobox protein 1 isoform X2", "protein_names_refseq": "paired mesoderm homeobox protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753942)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0071837 HMG box domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M8A5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6E6-1", "uniprot_id": [ { "id": "A0A8C2M6E6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M6E6", "type": "external" } ], "mass": 48322.0, "length": 427, "protein_name": "Stress-activated protein kinase JNK", "gene_name": "Mapk8", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase 8 isoform X2", "refseq_ac": [ { "id": "XP_003495363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495363", "type": "external" } ], "gene_names_uniprotkb": "Mapk8", "gene_names_refseq": "Mapk8", "protein_names_uniprotkb": "Stress-activated protein kinase JNK; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 8 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771734)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": 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}, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004705 JUN kinase activity;GO:0106310 protein serine kinase activity;GO:0042826 histone deacetylase binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005654 nucleoplasm", "go_biological_process": "GO:0048511 rhythmic process;GO:0010628 positive regulation of gene expression;GO:0051247 positive regulation of protein metabolic process;GO:0032880 regulation of protein localization;GO:0071260 cellular response to mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6E6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6G2-1", 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0098552 side of membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6G2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6G7-1", "uniprot_id": [ { "id": "A0A8C2M6G7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M6G7", "type": "external" } ], "mass": 82444.0, "length": 740, "protein_name": "ATP-dependent RNA helicase", "gene_name": "Ddx1", "organism": "Hamster", "refseq_name": "ATP-dependent RNA helicase DDX1", "refseq_ac": [ { "id": "XP_003502743", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502743", "type": "external" } ], "gene_names_uniprotkb": "Ddx1", "gene_names_refseq": "Ddx1", "protein_names_uniprotkb": "ATP-dependent RNA helicase; 3.6.4.13", "protein_names_refseq": "ATP-dependent RNA helicase DDX1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756637)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613907.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; RNA helicase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0033677 DNA/RNA helicase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0072669 tRNA-splicing ligase complex;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:1903608 protein localization to cytoplasmic stress granule;GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0051607 defense response to virus;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6G7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6J7-1", "uniprot_id": [ { "id": "A0A8C2M6J7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M6J7", "type": "external" } ], "mass": 51607.0, "length": 463, "protein_name": "V-type proton ATPase subunit S1", "gene_name": "Atp6ap1", "organism": "Hamster", "refseq_name": "V-type proton ATPase subunit S1 isoform X1", "refseq_ac": [ { "id": "XP_003512330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512330", "type": "external" } ], "gene_names_uniprotkb": "Atp6ap1", "gene_names_refseq": "Atp6ap1", "protein_names_uniprotkb": "V-type proton ATPase subunit S1; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; Vacuolar proton pump subunit S1", "protein_names_refseq": "V-type proton ATPase subunit S1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760638)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 212 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615411.1) and transcript sequence (IACG01092537.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003512330.1. COMPLETENESS: full length., [RefSeq]; Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca(2+)-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. In islets of Langerhans cells, may regulate the acidification of dense-core secretory granules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0033176 proton-transporting V-type ATPase complex;GO:0005789 endoplasmic reticulum membrane;GO:0010008 endosome membrane;GO:0030665 clathrin-coated vesicle membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0036035 osteoclast development;GO:0030641 regulation of cellular pH;GO:0036295 cellular response to increased oxygen levels;GO:0099638 endosome to plasma membrane protein transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6J7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6Q0-1", "uniprot_id": [ { "id": "A0A8C2M6Q0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M6Q0", "type": "external" } ], "mass": 51291.0, "length": 461, "protein_name": "Tubby-like protein", "gene_name": "Tulp3", "organism": "Hamster", "refseq_name": "tubby-related protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027284176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284176", "type": "external" } ], "gene_names_uniprotkb": "Tulp3", "gene_names_refseq": "Tulp3", "protein_names_uniprotkb": "Tubby-like protein", "protein_names_refseq": "tubby-related protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762976)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0030674 protein-macromolecule adaptor activity;GO:0001664 G protein-coupled receptor binding;GO:0035091 phosphatidylinositol binding;GO:0120160 intraciliary transport particle A binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005886 plasma membrane;GO:0005930 axoneme", "go_biological_process": "GO:0097499 protein localization to non-motile cilium;GO:0045879 negative regulation of smoothened signaling pathway;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6Q0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZY8-1", "uniprot_id": [ { "id": "A0A9J7FZY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZY8", "type": "external" } ], "mass": 123567.0, "length": 1078, "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "Pik3cb", "organism": "Hamster", "refseq_name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2", "refseq_ac": [ { "id": "XP_027270061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270061", "type": "external" } ], "gene_names_uniprotkb": "Pik3cb", "gene_names_refseq": "Pik3cb", "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; 2.7.1.153; 2.7.11.1; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; Serine/threonine protein kinase PIK3CB", "protein_names_refseq": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689252)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0043560 insulin receptor substrate binding;GO:0016303 1-phosphatidylinositol-3-kinase activity;GO:0046934 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005942 phosphatidylinositol 3-kinase complex", "go_biological_process": "GO:0003376 sphingosine-1-phosphate receptor signaling pathway;GO:0002931 response to ischemia;GO:0006897 endocytosis;GO:0007155 cell adhesion;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZY8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6T7-1", "uniprot_id": [ { "id": "A0A8C2M6T7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M6T7", "type": "external" } ], "mass": 80245.0, "length": 736, "protein_name": "E3 ubiquitin-protein ligase SH3RF2", "gene_name": "Sh3rf2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase SH3RF2 isoform X1", "refseq_ac": [ { "id": "XP_027253798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253798", "type": "external" } ], "gene_names_uniprotkb": "Sh3rf2", "gene_names_refseq": "Sh3rf2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase SH3RF2; 2.3.2.27; Protein phosphatase 1 regulatory subunit 39; RING finger protein 158; RING-type E3 ubiquitin transferase SH3RF2; SH3 domain-containing RING finger protein 2", "protein_names_refseq": "E3 ubiquitin-protein ligase SH3RF2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762724)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has E3 ubiquitin-protein ligase activity. Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation. Facilitates TNF-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation. Inhibits PPP1CA phosphatase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0008157 protein phosphatase 1 binding;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0043066 negative regulation of apoptotic process;GO:0046330 positive regulation of JNK cascade;GO:0031397 negative regulation of protein ubiquitination;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6T7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M6X8-1", "uniprot_id": [ { "id": "A0A8C2M6X8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M6X8", "type": "external" } ], "mass": 81737.0, "length": 707, "protein_name": "Protein kinase C", "gene_name": "Prkcq", "organism": "Hamster", "refseq_name": "protein kinase C theta type isoform X1", "refseq_ac": [ { "id": "XP_003494977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003494977", "type": "external" } ], "gene_names_uniprotkb": "Prkcq", "gene_names_refseq": "Prkcq", "protein_names_uniprotkb": "Protein kinase C; 2.7.11.13", "protein_names_refseq": "protein kinase C theta type isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762470)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613580.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0034451 centriolar satellite;GO:0001772 immunological synapse", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0032740 positive regulation of interleukin-17 production;GO:2000570 positive regulation of T-helper 2 cell activation;GO:0006509 membrane protein ectodomain proteolysis;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M6X8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M7B3-1", "uniprot_id": [ { "id": "A0A8C2M7B3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M7B3", "type": "external" } ], "mass": 74208.0, "length": 686, "protein_name": "Dihydropyrimidinase-related protein 1", "gene_name": "Crmp1", "organism": "Hamster", "refseq_name": "dihydropyrimidinase-related protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027242873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242873", "type": "external" } ], "gene_names_uniprotkb": "Crmp1", "gene_names_refseq": "Crmp1", "protein_names_uniprotkb": "Dihydropyrimidinase-related protein 1; Collapsin response mediator protein 1; Inactive dihydropyrimidinase", "protein_names_refseq": "dihydropyrimidinase-related protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113830864)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051219 phosphoprotein binding;GO:0031005 filamin binding;GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0030425 dendrite", "go_biological_process": "GO:0071526 semaphorin-plexin signaling pathway;GO:0010977 negative regulation of neuron projection development;GO:0150052 regulation of postsynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M7B3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M7G6-1", "uniprot_id": [ { "id": "A0A8C2M7G6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M7G6", "type": "external" } ], "mass": 70356.0, "length": 662, "protein_name": "Glutathione hydrolase", "gene_name": "Ggt7", "organism": "Hamster", "refseq_name": "glutathione hydrolase 7 isoform X1", "refseq_ac": [ { "id": "XP_027277182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277182", "type": "external" } ], "gene_names_uniprotkb": "Ggt7", "gene_names_refseq": "Ggt7", "protein_names_uniprotkb": "Glutathione hydrolase; 2.3.2.2; 3.4.19.13; Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase", "protein_names_refseq": "glutathione hydrolase 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752303)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.2", "type": "external" }, { "id": "3.4.19.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.13", "type": "external" }, { "id": "3.4.19.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.14", "type": "external" } ], "go_molecular_function": "GO:0036374 glutathione hydrolase activity;GO:0103068 leukotriene C4 gamma-glutamyl transferase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006750 glutathione biosynthetic process;GO:0006751 glutathione catabolic process;GO:1902883 negative regulation of response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M7G6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M7K8-1", "uniprot_id": [ { "id": "A0A8C2M7K8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M7K8", "type": "external" } ], "mass": 54803.0, "length": 509, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 4", "gene_name": "Slc2a4", "organism": "Hamster", "refseq_name": "solute carrier family 2, facilitated glucose transporter member 4 isoform X1", "refseq_ac": [ { "id": "XP_003497239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497239", "type": "external" } ], "gene_names_uniprotkb": "Slc2a4", "gene_names_refseq": "Slc2a4", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive", "protein_names_refseq": "solute carrier family 2, facilitated glucose transporter member 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766656)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0045121 membrane raft;GO:0048471 perinuclear region of cytoplasm;GO:0070062 extracellular exosome", "go_biological_process": "GO:0070837 dehydroascorbic acid transport;GO:1904659 D-glucose transmembrane transport;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M7K8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M7T8-1", "uniprot_id": [ { "id": "A0A8C2M7T8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M7T8", "type": "external" } ], "mass": 85369.0, "length": 780, "protein_name": "ATP-dependent 6-phosphofructokinase", "gene_name": "Pfkl", "organism": "Hamster", "refseq_name": "ATP-dependent 6-phosphofructokinase, liver type isoform X2", "refseq_ac": [ { "id": "XP_027250137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250137", "type": "external" } ], "gene_names_uniprotkb": "Pfkl", "gene_names_refseq": "Pfkl", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase; 2.7.1.11; ATP-PFK; Phosphofructokinase; Phosphohexokinase", "protein_names_refseq": "ATP-dependent 6-phosphofructokinase, liver type isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762127)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" } ], "go_molecular_function": "GO:0070095 fructose-6-phosphate binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0016208 AMP binding", "go_cellular_component": "GO:0016020 membrane;GO:0005945 6-phosphofructokinase complex", "go_biological_process": "GO:0009749 response to glucose;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M7T8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M7Y3-1", "uniprot_id": [ { "id": "A0A8C2M7Y3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M7Y3", "type": "external" } ], "mass": 17138.0, "length": 152, "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "Ube2n", "organism": "Hamster", "refseq_name": "ubiquitin-conjugating enzyme E2 N isoform X2", "refseq_ac": [ { "id": "XP_027249923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249923", "type": "external" } ], "gene_names_uniprotkb": "Ube2n", "gene_names_refseq": "Ube2n", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 N; 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubiquitin carrier protein N; Ubiquitin-protein ligase N", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 N isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752830)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0031625 ubiquitin protein ligase binding;GO:0043130 ubiquitin binding;GO:0097027 ubiquitin-protein transferase activator activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0001650 fibrillar center;GO:0000151 ubiquitin ligase complex;GO:0031372 UBC13-MMS2 complex", "go_biological_process": "GO:0050852 T cell receptor signaling pathway;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070534 protein K63-linked ubiquitination;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M7Y3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M8D5-1", "uniprot_id": [ { "id": "A0A8C2M8D5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M8D5", "type": "external" } ], "mass": 117349.0, "length": 1025, "protein_name": "Leucyl-cystinyl aminopeptidase", "gene_name": "Lnpep", "organism": "Hamster", "refseq_name": "leucyl-cystinyl aminopeptidase isoform X1", "refseq_ac": [ { "id": "XP_007638922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638922", "type": "external" } ], "gene_names_uniprotkb": "Lnpep", "gene_names_refseq": "Lnpep", "protein_names_uniprotkb": "Leucyl-cystinyl aminopeptidase; 3.4.11.3; Oxytocinase", "protein_names_refseq": "leucyl-cystinyl aminopeptidase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 199 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613767.1) and transcript sequence (IACG01053155.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007638922.1. COMPLETENESS: full length., [RefSeq]; Release of an N-terminal amino acid, cleave before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0008217 regulation of blood pressure;GO:0043171 peptide catabolic process;GO:0120163 negative regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M8D5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M8M9-1", "uniprot_id": [ { "id": "A0A8C2M8M9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M8M9", "type": "external" } ], "mass": 36169.0, "length": 326, "protein_name": "ELAV-like protein", "gene_name": "Elavl1", "organism": "Hamster", "refseq_name": "ELAV-like protein 1", "refseq_ac": [ { "id": "XP_003506274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506274", "type": "external" } ], "gene_names_uniprotkb": "Elavl1", "gene_names_refseq": "Elavl1", "protein_names_uniprotkb": "ELAV-like protein", "protein_names_refseq": "ELAV-like protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754131)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614218.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0003725 double-stranded RNA binding;GO:0035198 miRNA binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0060965 negative regulation of miRNA-mediated gene silencing;GO:0051260 protein homooligomerization;GO:0070935 3'-UTR-mediated mRNA stabilization;GO:2000036 regulation of stem cell population maintenance;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M8M9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M8V3-1", "uniprot_id": [ { "id": "A0A8C2M8V3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M8V3", "type": "external" } ], "mass": 98107.0, "length": 870, "protein_name": "Dynamin-2", "gene_name": "Dnm2", "organism": "Hamster", "refseq_name": "dynamin-2 isoform X2", "refseq_ac": [ { "id": "XP_027267343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267343", "type": "external" } ], "gene_names_uniprotkb": "Dnm2", "gene_names_refseq": "Dnm2", "protein_names_uniprotkb": "Dynamin-2; 3.6.5.5", "protein_names_refseq": "dynamin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771373)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005874 microtubule;GO:0005905 clathrin-coated pit;GO:0014069 postsynaptic density;GO:0055037 recycling endosome", "go_biological_process": "GO:0031623 receptor internalization;GO:0006909 phagocytosis;GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M8V3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EUZ9-1", "uniprot_id": [ { "id": "A0A9J7EUZ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EUZ9", "type": "external" } ], "mass": 88308.0, "length": 803, "protein_name": "Fibroblast growth factor receptor", "gene_name": "Fgfr3", "organism": "Hamster", "refseq_name": "fibroblast growth factor receptor 3 isoform X1", "refseq_ac": [ { "id": "XP_016831950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831950", "type": "external" } ], "gene_names_uniprotkb": "Fgfr3", "gene_names_refseq": "Fgfr3", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "fibroblast growth factor receptor 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764560)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614033.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0008283 cell population proliferation;GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0006915 apoptotic process;GO:0060349 bone morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EUZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M8V9-1", "uniprot_id": [ { "id": "A0A8C2M8V9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M8V9", "type": "external" } ], "mass": 60199.0, "length": 533, "protein_name": "Thromboxane-A synthase", "gene_name": "Tbxas1", "organism": "Hamster", "refseq_name": "thromboxane-A synthase isoform X2", "refseq_ac": [ { "id": "XP_027247309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247309", "type": "external" } ], "gene_names_uniprotkb": "Tbxas1", "gene_names_refseq": "Tbxas1", "protein_names_uniprotkb": "Thromboxane-A synthase; 4.2.1.152; 5.3.99.5; Cytochrome P450 5A1; Hydroperoxy icosatetraenoate dehydratase", "protein_names_refseq": "thromboxane-A synthase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772642)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "4.2.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.152", "type": "external" }, { "id": "5.3.99.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.5", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "5.3.99.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.4", "type": "external" }, { "id": "1.14.99.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008395 steroid hydroxylase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004796 thromboxane-A synthase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M8V9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M8Z5-1", "uniprot_id": [ { "id": "A0A8C2M8Z5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M8Z5", "type": "external" } ], "mass": 80782.0, "length": 727, "protein_name": "Plakophilin-1", "gene_name": "Pkp1", "organism": "Hamster", "refseq_name": "plakophilin-1 isoform X2", "refseq_ac": [ { "id": "XP_027273298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273298", "type": "external" } ], "gene_names_uniprotkb": "Pkp1", "gene_names_refseq": "Pkp1", "protein_names_uniprotkb": "Plakophilin-1", "protein_names_refseq": "plakophilin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764930)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005521 lamin binding", "go_cellular_component": "GO:0097165 nuclear stress granule;GO:0005912 adherens junction;GO:0048471 perinuclear region of cytoplasm;GO:0001533 cornified envelope;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0045110 intermediate filament bundle assembly;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0098609 cell-cell adhesion;GO:1903078 positive regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M8Z5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M9B4-1", "uniprot_id": [ { "id": "A0A8C2M9B4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M9B4", "type": "external" } ], "mass": 93097.0, "length": 825, "protein_name": "Intraflagellar transport protein 88 homolog", "gene_name": "Ift88", "organism": "Hamster", "refseq_name": "intraflagellar transport protein 88 homolog isoform X3", "refseq_ac": [ { "id": "XP_003500476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500476", "type": "external" } ], "gene_names_uniprotkb": "Ift88", "gene_names_refseq": "Ift88", "protein_names_uniprotkb": "Intraflagellar transport protein 88 homolog; Tetratricopeptide repeat protein 10", "protein_names_refseq": "intraflagellar transport protein 88 homolog isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761553)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613790.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0031514 motile cilium;GO:0005814 centriole;GO:0097730 non-motile cilium", "go_biological_process": "GO:0001822 kidney development;GO:1905515 non-motile cilium assembly;GO:0042073 intraciliary transport;GO:0045724 positive regulation of cilium assembly;GO:0060122 inner ear receptor cell stereocilium organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M9B4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M9K1-1", "uniprot_id": [ { "id": "A0A8C2M9K1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M9K1", "type": "external" } ], "mass": 26508.0, "length": 232, "protein_name": "Charged multivesicular body protein 4c", "gene_name": "Chmp4c", "organism": "Hamster", "refseq_name": "charged multivesicular body protein 4c", "refseq_ac": [ { "id": "XP_027254556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254556", "type": "external" } ], "gene_names_uniprotkb": "Chmp4c", "gene_names_refseq": "Chmp4c", "protein_names_uniprotkb": "Charged multivesicular body protein 4c", "protein_names_refseq": "charged multivesicular body protein 4c", "tax_id": 10029, "disease": "", "pathway": " (cge:100759934)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005828 kinetochore microtubule;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0010824 regulation of centrosome duplication;GO:0031468 nuclear membrane reassembly;GO:0039702 viral budding via host ESCRT complex;GO:0097352 autophagosome maturation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M9K1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M9V4-1", "uniprot_id": [ { "id": "A0A8C2M9V4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M9V4", "type": "external" } ], "mass": 106409.0, "length": 966, "protein_name": "Thrombospondin-4", "gene_name": "Thbs4", "organism": "Hamster", "refseq_name": "thrombospondin-4 isoform X2", "refseq_ac": [ { "id": "XP_027257535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257535", "type": "external" } ], "gene_names_uniprotkb": "Thbs4", "gene_names_refseq": "Thbs4", "protein_names_uniprotkb": "Thrombospondin-4", "protein_names_refseq": "thrombospondin-4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762358)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0005509 calcium ion binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005604 basement membrane;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0071603 endothelial cell-cell adhesion;GO:0001938 positive regulation of endothelial cell proliferation;GO:0051781 positive regulation of cell division;GO:0016525 negative regulation of angiogenesis;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M9V4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2M9Y1-1", "uniprot_id": [ { "id": "A0A8C2M9Y1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2M9Y1", "type": "external" } ], "mass": 40029.0, "length": 358, "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "Nsdhl", "organism": "Hamster", "refseq_name": "sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "refseq_ac": [ { "id": "XP_003514005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514005", "type": "external" } ], "gene_names_uniprotkb": "Nsdhl", "gene_names_refseq": "Nsdhl", "protein_names_uniprotkb": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; 1.1.1.170", "protein_names_refseq": "sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "tax_id": 10029, "disease": "", "pathway": " (cge:100764429)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 734 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616242.1) and transcript sequence (IACG01086788.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003514005.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.170", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.170", "type": "external" } ], "go_molecular_function": "GO:0000252 3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0033489 cholesterol biosynthetic process via desmosterol;GO:0033490 cholesterol biosynthetic process via lathosterol;GO:0036197 zymosterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2M9Y1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MAC8-1", "uniprot_id": [ { "id": "A0A8C2MAC8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MAC8", "type": "external" } ], "mass": 97211.0, "length": 876, "protein_name": "Importin subunit beta-1", "gene_name": "Kpnb1", "organism": "Hamster", "refseq_name": "importin subunit beta-1 isoform X1", "refseq_ac": [ { "id": "XP_007638520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638520", "type": "external" } ], "gene_names_uniprotkb": "Kpnb1", "gene_names_refseq": "Kpnb1", "protein_names_uniprotkb": "Importin subunit beta-1; Karyopherin subunit beta-1; Nuclear factor p97; Pore targeting complex 97 kDa subunit", "protein_names_refseq": "importin subunit beta-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762896)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 184 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613745.1) and transcript sequence (JP046199.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061676 importin-alpha family protein binding;GO:0019904 protein domain specific binding;GO:0031267 small GTPase binding;GO:0051879 Hsp90 protein binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0031965 nuclear membrane;GO:0010494 cytoplasmic stress granule;GO:0032991 protein-containing complex", "go_biological_process": "GO:0007079 mitotic chromosome movement towards spindle pole;GO:0006610 ribosomal protein import into nucleus;GO:0090307 mitotic spindle assembly;GO:0007080 mitotic metaphase chromosome alignment;GO:0040001 establishment of mitotic spindle localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MAC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCF8-1", "uniprot_id": [ { "id": "A0A8C2MCF8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCF8", "type": "external" } ], "mass": 76358.0, "length": 659, "protein_name": "Tyrosine-protein kinase", "gene_name": "Btk", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase BTK isoform X3", "refseq_ac": [ { "id": "XP_035305963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305963", "type": "external" } ], "gene_names_uniprotkb": "Btk", "gene_names_refseq": "Btk", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase BTK isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100772144)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0042113 B cell activation;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCF8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MAD7-1", "uniprot_id": [ { "id": "A0A8C2MAD7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MAD7", "type": "external" } ], "mass": 35551.0, "length": 313, "protein_name": "Serine/threonine-protein kinase", "gene_name": "Pim1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase pim-1 isoform X2", "refseq_ac": [ { "id": "XP_027250232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250232", "type": "external" } ], "gene_names_uniprotkb": "Pim1", "gene_names_refseq": "Pim1", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pim-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751275)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030145 manganese ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0070561 vitamin D receptor signaling pathway;GO:1905062 positive regulation of cardioblast proliferation;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MAD7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MAK1-1", "uniprot_id": [ { "id": "A0A8C2MAK1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MAK1", "type": "external" } ], "mass": 67794.0, "length": 604, "protein_name": "Netrin-1", "gene_name": "Ntn1", "organism": "Hamster", "refseq_name": "netrin-1 isoform X2", "refseq_ac": [ { "id": "XP_035303371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303371", "type": "external" } ], "gene_names_uniprotkb": "Ntn1", "gene_names_refseq": "Ntn1", "protein_names_uniprotkb": "Netrin-1", "protein_names_refseq": "netrin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750350)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005576 extracellular region;GO:0005829 cytosol;GO:0005604 basement membrane", "go_biological_process": "GO:0016358 dendrite development;GO:0009887 animal organ morphogenesis;GO:0051963 regulation of synapse assembly;GO:0045773 positive regulation of axon extension;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MAK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MAL1-1", "uniprot_id": [ { "id": "A0A8C2MAL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MAL1", "type": "external" } ], "mass": 123759.0, "length": 1155, "protein_name": "Multiple epidermal growth factor-like domains protein 10", "gene_name": "Megf10", "organism": "Hamster", "refseq_name": "multiple epidermal growth factor-like domains protein 10", "refseq_ac": [ { "id": "XP_035296031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296031", "type": "external" } ], "gene_names_uniprotkb": "Megf10", "gene_names_refseq": "Megf10", "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 10", "protein_names_refseq": "multiple epidermal growth factor-like domains protein 10", "tax_id": 10029, "disease": "", "pathway": " (cge:100757958)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005112 Notch binding;GO:0001849 complement component C1q complex binding", "go_cellular_component": "GO:0001891 phagocytic cup", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0014816 skeletal muscle satellite cell differentiation;GO:0034109 homotypic cell-cell adhesion;GO:0006909 phagocytosis;GO:0051451 myoblast migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MAL1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MAM4-1", "uniprot_id": [ { "id": "A0A8C2MAM4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MAM4", "type": "external" } ], "mass": 155674.0, "length": 1372, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "Insr", "organism": "Hamster", "refseq_name": "insulin receptor isoform X2", "refseq_ac": [ { "id": "XP_027271565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271565", "type": "external" } ], "gene_names_uniprotkb": "Insr", "gene_names_refseq": "Insr", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "insulin receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766818)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005009 insulin receptor activity;GO:0005524 ATP binding;GO:0043560 insulin receptor substrate binding;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0030424 axon;GO:0005764 lysosome;GO:0005770 late endosome;GO:0005899 insulin receptor complex", "go_biological_process": "GO:0048731 system development;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0043410 positive regulation of MAPK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0010906 regulation of glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MAM4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MAV1-1", "uniprot_id": [ { "id": "A0A8C2MAV1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MAV1", "type": "external" } ], "mass": 23050.0, "length": 208, "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "Hbegf", "organism": "Hamster", "refseq_name": "proheparin-binding EGF-like growth factor isoform X1", "refseq_ac": [ { "id": "XP_007649166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649166", "type": "external" } ], "gene_names_uniprotkb": "Hbegf", "gene_names_refseq": "Hbegf", "protein_names_uniprotkb": "Proheparin-binding EGF-like growth factor", "protein_names_refseq": "proheparin-binding EGF-like growth factor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689423)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 500 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614866.1) and transcript sequence (IACG01045661.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity;GO:0030297 transmembrane receptor protein tyrosine kinase activator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0051549 positive regulation of keratinocyte migration;GO:0048661 positive regulation of smooth muscle cell proliferation;GO:0090303 positive regulation of wound healing;GO:0060326 cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MAV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MB01-1", "uniprot_id": [ { "id": "A0A8C2MB01_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MB01", "type": "external" } ], "mass": 34495.0, "length": 307, "protein_name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "gene_name": "Nmnat2", "organism": "Hamster", "refseq_name": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "refseq_ac": [ { "id": "XP_027273166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273166", "type": "external" } ], "gene_names_uniprotkb": "Nmnat2", "gene_names_refseq": "Nmnat2", "protein_names_uniprotkb": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; 2.7.7.18; 2.7.7.1; Nicotinamide mononucleotide adenylyltransferase 2; Nicotinate-nucleotide adenylyltransferase 2", "protein_names_refseq": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761270)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.1", "type": "external" }, { "id": "2.7.7.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.18", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004515 nicotinate-nucleotide adenylyltransferase activity;GO:0000309 nicotinamide-nucleotide adenylyltransferase activity;GO:0140768 protein ADP-ribosyltransferase-substrate adaptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0030424 axon;GO:0045202 synapse;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0006741 NADP+ biosynthetic process;GO:2000766 negative regulation of cytoplasmic translation;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan;GO:0034355 NAD+ biosynthetic process via the salvage pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MB01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MB35-1", "uniprot_id": [ { "id": "A0A8C2MB35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MB35", "type": "external" } ], "mass": 85291.0, "length": 772, "protein_name": "Nucleolar RNA helicase 2", "gene_name": "Ddx21; LOC100774208", "organism": "Hamster", "refseq_name": "nucleolar RNA helicase 2", "refseq_ac": [ { "id": "XP_007638831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638831", "type": "external" } ], "gene_names_uniprotkb": "Ddx21; LOC100774208", "gene_names_refseq": "Ddx21", "protein_names_uniprotkb": "Nucleolar RNA helicase 2; 3.6.4.13; DEAD box protein 21; Gu-alpha; Nucleolar RNA helicase Gu; Nucleolar RNA helicase II; RH II/Gu", "protein_names_refseq": "nucleolar RNA helicase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771185); (cge:100774208)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613759.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MB35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MB66-1", "uniprot_id": [ { "id": "A0A8C2MB66_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MB66", "type": "external" } ], "mass": 143945.0, "length": 1307, "protein_name": "Cyclin-G-associated kinase", "gene_name": "Gak", "organism": "Hamster", "refseq_name": "cyclin-G-associated kinase isoform X1", "refseq_ac": [ { "id": "XP_027281752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281752", "type": "external" } ], "gene_names_uniprotkb": "Gak", "gene_names_refseq": "Gak", "protein_names_uniprotkb": "Cyclin-G-associated kinase; 2.7.11.1; DnaJ homolog subfamily C member 26", "protein_names_refseq": "cyclin-G-associated kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766883)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. May play a role in clathrin-mediated endocytosis and intracellular trafficking, and in the dynamics of clathrin assembly/disassembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030276 clathrin binding;GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0048471 perinuclear region of cytoplasm;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0010977 negative regulation of neuron projection development;GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis;GO:0090160 Golgi to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MB66-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MBD4-1", "uniprot_id": [ { "id": "A0A8C2MBD4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MBD4", "type": "external" } ], "mass": 112150.0, "length": 1009, "protein_name": "Glutamate receptor", "gene_name": "Grid1", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, delta-1 isoform X2", "refseq_ac": [ { "id": "XP_035308690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308690", "type": "external" } ], "gene_names_uniprotkb": "Grid1", "gene_names_refseq": "Grid1", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, delta-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760535)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Member of the ionotropic glutamate receptor family, which plays a crucial role in synaptic organization and signal transduction in the central nervous system. Although it shares structural features with ionotropic glutamate receptors, does not bind glutamate as a primary ligand. Instead, forms trans-synaptic adhesion complexes with presynaptic neurexins and cerebellins, regulating NMDA and AMPA receptor activity and influencing synaptic plasticity through signal transduction. In the presence of NRX1B-CBLN1, forms cation-selective channels that are proposed to be gated by glycine and D-serine. However, recent research disputes this ligand-gated cation channel activity. Cation-selective ion channel can be triggered by GRM1 in dopaminergic neurons. Also acts as a receptor for GABA, modulating inhibitory synaptic plasticity through non-ionotropic mechanisms., [UniProtKB, UniProtKB]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0016917 GABA receptor activity;GO:0030545 signaling receptor regulator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0098839 postsynaptic density membrane;GO:0098820 trans-synaptic protein complex", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0035176 social behavior;GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission;GO:0031914 negative regulation of synaptic plasticity;GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MBD4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MBX6-1", "uniprot_id": [ { "id": "A0A8C2MBX6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MBX6", "type": "external" } ], "mass": 7009.0, "length": 68, "protein_name": "Metallothionein", "gene_name": "Mt3", "organism": "Hamster", "refseq_name": "metallothionein-3", "refseq_ac": [ { "id": "XP_035297306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297306", "type": "external" } ], "gene_names_uniprotkb": "Mt3", "gene_names_refseq": "Mt3", "protein_names_uniprotkb": "Metallothionein", "protein_names_refseq": "metallothionein-3", "tax_id": 10029, "disease": "", "pathway": " (cge:107978039)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046870 cadmium ion binding;GO:0008270 zinc ion binding;GO:0030295 protein kinase activator activity;GO:0005507 copper ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0008021 synaptic vesicle;GO:0016234 inclusion body", "go_biological_process": "GO:0006829 zinc ion transport;GO:0010628 positive regulation of gene expression;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0043524 negative regulation of neuron apoptotic process;GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MBX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MC97-1", "uniprot_id": [ { "id": "A0A8C2MC97_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MC97", "type": "external" } ], "mass": 139385.0, "length": 1233, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "Plcb3", "organism": "Hamster", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X2", "refseq_ac": [ { "id": "XP_027264242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264242", "type": "external" } ], "gene_names_uniprotkb": "Plcb3", "gene_names_refseq": "Plcb3", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760134)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Key transducer of G protein-coupled receptor signaling: activated by G(q)/G(11) G alpha proteins downstream of G protein-coupled receptors activation. In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" } ], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005516 calmodulin binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016020 membrane;GO:0032991 protein-containing complex;GO:0099524 postsynaptic cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0051209 release of sequestered calcium ion into cytosol;GO:0007208 phospholipase C-activating serotonin receptor signaling pathway;GO:0048015 phosphatidylinositol-mediated signaling;GO:0046488 phosphatidylinositol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MC97-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCA5-1", "uniprot_id": [ { "id": "A0A8C2MCA5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCA5", "type": "external" } ], "mass": 71548.0, "length": 638, "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "Ddx41", "organism": "Hamster", "refseq_name": "probable ATP-dependent RNA helicase DDX41", "refseq_ac": [ { "id": "XP_003498197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498197", "type": "external" } ], "gene_names_uniprotkb": "Ddx41", "gene_names_refseq": "Ddx41", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX41; 3.6.4.13; DEAD box protein 41", "protein_names_refseq": "probable ATP-dependent RNA helicase DDX41", "tax_id": 10029, "disease": "", "pathway": " (cge:100770508)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613681.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0008283 cell population proliferation;GO:0030154 cell differentiation;GO:0000398 mRNA splicing, via spliceosome;GO:0140896 cGAS/STING signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCF6-1", "uniprot_id": [ { "id": "A0A8C2MCF6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCF6", "type": "external" } ], "mass": 35951.0, "length": 308, "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "Tecr", "organism": "Hamster", "refseq_name": "very-long-chain enoyl-CoA reductase isoform X2", "refseq_ac": [ { "id": "XP_027261959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261959", "type": "external" } ], "gene_names_uniprotkb": "Tecr", "gene_names_refseq": "Tecr", "protein_names_uniprotkb": "Very-long-chain enoyl-CoA reductase; 1.3.1.93; Synaptic glycoprotein SC2; Trans-2,3-enoyl-CoA reductase", "protein_names_refseq": "very-long-chain enoyl-CoA reductase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761652)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of the sphingosine moiety in sphingolipids through the sphingosine 1-phosphate metabolic pathway. Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Catalyzes the saturation step of the sphingosine 1-phosphate metabolic pathway, the conversion of trans-2-hexadecenoyl-CoA to palmitoyl-CoA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.93", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.93", "type": "external" } ], "go_molecular_function": "GO:0102758 very-long-chain enoyl-CoA reductase activity;GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006665 sphingolipid metabolic process;GO:0006694 steroid biosynthetic process;GO:0042761 very long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCJ6-1", "uniprot_id": [ { "id": "A0A8C2MCJ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCJ6", "type": "external" } ], "mass": 56371.0, "length": 529, "protein_name": "ATP synthase subunit beta", "gene_name": "Atp5f1b", "organism": "Hamster", "refseq_name": "ATP synthase subunit beta, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003506224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506224", "type": "external" } ], "gene_names_uniprotkb": "Atp5f1b", "gene_names_refseq": "Atp5f1b", "protein_names_uniprotkb": "ATP synthase subunit beta; 7.1.2.2", "protein_names_refseq": "ATP synthase subunit beta, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763024)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 164 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614217.1) and transcript sequence (IACG01093905.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003506224.1. COMPLETENESS: full length., [RefSeq]; Catalytic subunit beta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. With the subunit alpha (ATP5F1A), forms the catalytic core in the F(1) domain., [UniProtKB, UniProtKB]; Produces ATP from ADP in the presence of a proton gradient across the membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0043532 angiostatin binding;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism;GO:0042288 MHC class I protein binding;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0042645 mitochondrial nucleoid;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0043536 positive regulation of blood vessel endothelial cell migration;GO:0042776 proton motive force-driven mitochondrial ATP synthesis;GO:0051453 regulation of intracellular pH", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MDW0-1", "uniprot_id": [ { "id": "A0A8C2MDW0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MDW0", "type": "external" } ], "mass": 100780.0, "length": 902, "protein_name": "Glutamate receptor", "gene_name": "Gria4", "organism": "Hamster", "refseq_name": "glutamate receptor 4 isoform X2", "refseq_ac": [ { "id": "XP_035299319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299319", "type": "external" } ], "gene_names_uniprotkb": "Gria4", "gene_names_refseq": "Gria4", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755681)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic acid, and kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system and plays an important role in fast excitatory synaptic transmission. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse upon entry of monovalent and divalent cations such as sodium and calcium. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of L-glutamate., [UniProtKB, UniProtKB, UniProtKB]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0022824 transmitter-gated monoatomic ion channel activity;GO:0004971 AMPA glutamate receptor activity;GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential", "go_cellular_component": "GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0030425 dendrite;GO:0045211 postsynaptic membrane;GO:0032281 AMPA glutamate receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007268 chemical synaptic transmission;GO:0034392 negative regulation of smooth muscle cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MDW0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCX3-1", "uniprot_id": [ { "id": "A0A8C2MCX3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCX3", "type": "external" } ], "mass": 34209.0, "length": 302, "protein_name": "Cyclin-dependent kinase 2", "gene_name": "Cdk3", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase 3 isoform X2", "refseq_ac": [ { "id": "XP_007645558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645558", "type": "external" } ], "gene_names_uniprotkb": "Cdk3", "gene_names_refseq": "Cdk3", "protein_names_uniprotkb": "Cyclin-dependent kinase 2; 2.7.11.22; Cell division protein kinase 2", "protein_names_refseq": "cyclin-dependent kinase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614300.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0030332 cyclin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005813 centrosome;GO:0015030 Cajal body;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0006281 DNA repair;GO:0007165 signal transduction;GO:0051301 cell division;GO:0010389 regulation of G2/M transition of mitotic cell cycle;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCX3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCX5-1", "uniprot_id": [ { "id": "A0A8C2MCX5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCX5", "type": "external" } ], "mass": 51323.0, "length": 475, "protein_name": "Trifunctional enzyme subunit beta, mitochondrial", "gene_name": "Hadhb", "organism": "Hamster", "refseq_name": "trifunctional enzyme subunit beta, mitochondrial", "refseq_ac": [ { "id": "XP_003497068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497068", "type": "external" } ], "gene_names_uniprotkb": "Hadhb", "gene_names_refseq": "Hadhb", "protein_names_uniprotkb": "Trifunctional enzyme subunit beta, mitochondrial; 2.3.1.155; 2.3.1.16; TP-beta", "protein_names_refseq": "trifunctional enzyme subunit beta, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100758239)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" } ], "go_molecular_function": "GO:0003985 acetyl-CoA C-acetyltransferase activity;GO:0050633 acetyl-CoA C-myristoyltransferase activity;GO:0106222 lncRNA binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum;GO:0042645 mitochondrial nucleoid;GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0071222 cellular response to lipopolysaccharide;GO:0010467 gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MCZ0-1", "uniprot_id": [ { "id": "A0A8C2MCZ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MCZ0", "type": "external" } ], "mass": 52747.0, "length": 475, "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "gene_name": "Slc25a24", "organism": "Hamster", "refseq_name": "calcium-binding mitochondrial carrier protein SCaMC-1", "refseq_ac": [ { "id": "XP_027251341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251341", "type": "external" } ], "gene_names_uniprotkb": "Slc25a24", "gene_names_refseq": "Slc25a24", "protein_names_uniprotkb": "Mitochondrial adenyl nucleotide antiporter SLC25A24; Small calcium-binding mitochondrial carrier protein 1; Solute carrier family 25 member 24", "protein_names_refseq": "calcium-binding mitochondrial carrier protein SCaMC-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754168)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool, could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0140987 ATP:phosphate antiporter activity;GO:0140988 ADP:phosphate antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0071277 cellular response to calcium ion;GO:0034599 cellular response to oxidative stress;GO:1990544 mitochondrial ATP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MCZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MDB0-1", "uniprot_id": [ { "id": "A0A8C2MDB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MDB0", "type": "external" } ], "mass": 32339.0, "length": 285, "protein_name": "Tissue factor", "gene_name": "F3", "organism": "Hamster", "refseq_name": "tissue factor isoform X1", "refseq_ac": [ { "id": "XP_007652909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652909", "type": "external" } ], "gene_names_uniprotkb": "F3", "gene_names_refseq": "F3", "protein_names_uniprotkb": "Tissue factor; TF", "protein_names_refseq": "tissue factor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765608)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 150 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616817.1) and transcript sequence (JI891547.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0004252 serine-type endopeptidase activity;GO:0005543 phospholipid binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0009897 external side of plasma membrane;GO:1905286 serine-type peptidase complex", "go_biological_process": "GO:0007596 blood coagulation;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation;GO:0032008 positive regulation of TOR signaling;GO:0002543 activation of blood coagulation via clotting cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MDB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MDR9-1", "uniprot_id": [ { "id": "A0A8C2MDR9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MDR9", "type": "external" } ], "mass": 95859.0, "length": 901, "protein_name": "Nuclear factor of activated T-cells, cytoplasmic 4", "gene_name": "Nfatc4", "organism": "Hamster", "refseq_name": "nuclear factor of activated T-cells, cytoplasmic 4", "refseq_ac": [ { "id": "XP_027246327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246327", "type": "external" } ], "gene_names_uniprotkb": "Nfatc4", "gene_names_refseq": "Nfatc4", "protein_names_uniprotkb": "Nuclear factor of activated T-cells, cytoplasmic 4", "protein_names_refseq": "nuclear factor of activated T-cells, cytoplasmic 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100768420)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043524 negative regulation of neuron apoptotic process;GO:0030178 negative regulation of Wnt signaling pathway;GO:0007616 long-term memory", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MDR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2ME43-1", "uniprot_id": [ { "id": "A0A8C2ME43_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2ME43", "type": "external" } ], "mass": 226190.0, "length": 1985, "protein_name": "Sodium channel protein", "gene_name": "Scn9a", "organism": "Hamster", "refseq_name": "sodium channel protein type 9 subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_027276063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276063", "type": "external" } ], "gene_names_uniprotkb": "Scn9a", "gene_names_refseq": "Scn9a", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel protein type 9 subunit alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751370)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0043679 axon terminus;GO:0033268 node of Ranvier;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0019228 neuronal action potential;GO:0050965 detection of temperature stimulus involved in sensory perception of pain;GO:0086010 membrane depolarization during action potential;GO:0007623 circadian rhythm;GO:0050974 detection of mechanical stimulus involved in sensory perception", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2ME43-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2ME55-1", "uniprot_id": [ { "id": "A0A8C2ME55_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2ME55", "type": "external" } ], "mass": 39668.0, "length": 354, "protein_name": "Paraoxonase", "gene_name": "Pon3", "organism": "Hamster", "refseq_name": "serum paraoxonase/lactonase 3 isoform X1", "refseq_ac": [ { "id": "XP_027245683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245683", "type": "external" } ], "gene_names_uniprotkb": "Pon3", "gene_names_refseq": "Pon3", "protein_names_uniprotkb": "Paraoxonase; 3.1.1.2", "protein_names_refseq": "serum paraoxonase/lactonase 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762826)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.2", "type": "external" } ], "go_molecular_function": "GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0004064 arylesterase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0046395 carboxylic acid catabolic process;GO:0032929 negative regulation of superoxide anion generation;GO:0009636 response to toxic substance;GO:2001038 regulation of cellular response to drug;GO:1901335 lactone catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2ME55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MEG3-1", "uniprot_id": [ { "id": "A0A8C2MEG3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MEG3", "type": "external" } ], "mass": 74075.0, "length": 671, "protein_name": "Diacylglycerol lipase-beta", "gene_name": "Daglb", "organism": "Hamster", "refseq_name": "diacylglycerol lipase-beta isoform X1", "refseq_ac": [ { "id": "XP_003496355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496355", "type": "external" } ], "gene_names_uniprotkb": "Daglb", "gene_names_refseq": "Daglb", "protein_names_uniprotkb": "Diacylglycerol lipase-beta; 3.1.1.116; 3.1.1.3; PUFA-specific triacylglycerol lipase; Sn1-specific diacylglycerol lipase beta", "protein_names_refseq": "diacylglycerol lipase-beta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765603)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613618.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lipase that catalyzes the hydrolysis of arachidonic acid (AA)-esterified diacylglycerols (DAGs) to produce the principal endocannabinoid, 2-arachidonoylglycerol (2-AG) which can be further cleaved by downstream enzymes to release arachidonic acid (AA) for cyclooxygenase (COX)-mediated eicosanoid production. Preferentially hydrolyzes DAGs at the sn-1 position in a calcium-dependent manner and has negligible activity against other lipids including monoacylglycerols and phospholipids. Plays a key role in the regulation of 2-AG and AA pools utilized by COX1/2 to generate lipid mediators of macrophage and microglia inflammatory responses. Also functions as a polyunsaturated fatty acids-specific triacylglycerol lipase in macrophages. Plays an important role to support the metabolic and signaling demands of macrophages., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0047372 monoacylglycerol lipase activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0010898 positive regulation of triglyceride catabolic process;GO:0050727 regulation of inflammatory response;GO:0046340 diacylglycerol catabolic process;GO:0022008 neurogenesis;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MEG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MEU5-1", "uniprot_id": [ { "id": "A0A8C2MEU5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MEU5", "type": "external" } ], "mass": 82582.0, "length": 752, "protein_name": "MAP/microtubule affinity-regulating kinase 4", "gene_name": "Mark4", "organism": "Hamster", "refseq_name": "MAP/microtubule affinity-regulating kinase 4 isoform X2", "refseq_ac": [ { "id": "XP_027286706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286706", "type": "external" } ], "gene_names_uniprotkb": "Mark4", "gene_names_refseq": "Mark4", "protein_names_uniprotkb": "MAP/microtubule affinity-regulating kinase 4; 2.7.11.1", "protein_names_refseq": "MAP/microtubule affinity-regulating kinase 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754604)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008093 cytoskeletal anchor activity;GO:0050321 tau-protein kinase activity;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0030425 dendrite;GO:0005930 axoneme;GO:0030496 midbody", "go_biological_process": "GO:0007399 nervous system development;GO:0035556 intracellular signal transduction;GO:0051301 cell division;GO:1904781 positive regulation of protein localization to centrosome;GO:0046605 regulation of centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MEU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MEX1-1", "uniprot_id": [ { "id": "A0A8C2MEX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MEX1", "type": "external" } ], "mass": 162823.0, "length": 1453, "protein_name": "Erbin", "gene_name": "Erbin", "organism": "Hamster", "refseq_name": "erbin isoform X7", "refseq_ac": [ { "id": "XP_035296432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296432", "type": "external" } ], "gene_names_uniprotkb": "Erbin", "gene_names_refseq": "Erbin", "protein_names_uniprotkb": "Erbin; Densin-180-like protein; Erbb2-interacting protein; Protein LAP2", "protein_names_refseq": "erbin isoform X7", "tax_id": 10029, "disease": "", "pathway": " (cge:100774374)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0032496 response to lipopolysaccharide;GO:0098609 cell-cell adhesion;GO:0071638 negative regulation of monocyte chemotactic protein-1 production;GO:0043113 receptor clustering", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MEX1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MFN1-1", "uniprot_id": [ { "id": "A0A8C2MFN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MFN1", "type": "external" } ], "mass": 86957.0, "length": 757, "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "Ikbkb", "organism": "Hamster", "refseq_name": "inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1", "refseq_ac": [ { "id": "XP_003503362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503362", "type": "external" } ], "gene_names_uniprotkb": "Ikbkb", "gene_names_refseq": "Ikbkb", "protein_names_uniprotkb": "Inhibitor of nuclear factor kappa-B kinase subunit beta; 2.7.11.10; 2.7.11.1; I-kappa-B kinase 2; Nuclear factor NF-kappa-B inhibitor kinase beta; Serine/threonine protein kinase IKBKB", "protein_names_refseq": "inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750488)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613958.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008142 oxysterol binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0008013 beta-catenin binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0001525 angiogenesis;GO:0006351 DNA-templated transcription;GO:0010575 positive regulation of vascular endothelial growth factor production;GO:0010906 regulation of glucose metabolic process;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MGD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MGK9-1", "uniprot_id": [ { "id": "A0A8C2MGK9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MGK9", "type": "external" } ], "mass": 28528.0, "length": 249, "protein_name": "Inhibitor of growth protein", "gene_name": "Ing4", "organism": "Hamster", "refseq_name": "inhibitor of growth protein 4 isoform X1", "refseq_ac": [ { "id": "XP_003496102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496102", "type": "external" } ], "gene_names_uniprotkb": "Ing4", "gene_names_refseq": "Ing4", "protein_names_uniprotkb": "Inhibitor of growth protein", "protein_names_refseq": "inhibitor of growth protein 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754938)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613610.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of an histone acetyltransferase complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043997 histone H4K12 acetyltransferase activity;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0043995 histone H4K5 acetyltransferase activity;GO:0043996 histone H4K8 acetyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000123 histone acetyltransferase complex;GO:0005634 nucleus", "go_biological_process": "GO:2000278 regulation of DNA biosynthetic process;GO:0008285 negative regulation of cell population proliferation;GO:0043065 positive regulation of apoptotic process;GO:0045892 negative regulation of DNA-templated transcription;GO:0001558 regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MGK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI07-1", "uniprot_id": [ { "id": "A0A9J7FI07_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI07", "type": "external" } ], "mass": 82279.0, "length": 746, "protein_name": "alpha-1,2-Mannosidase", "gene_name": "Man1a1", "organism": "Hamster", "refseq_name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X2", "refseq_ac": [ { "id": "XP_027257887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257887", "type": "external" } ], "gene_names_uniprotkb": "Man1a1", "gene_names_refseq": "Man1a1", "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-", "protein_names_refseq": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767553)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0070062 extracellular exosome;GO:0031410 cytoplasmic vesicle;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0036503 ERAD pathway;GO:0045047 protein targeting to ER", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MH88-1", "uniprot_id": [ { "id": "A0A8C2MH88_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MH88", "type": "external" } ], "mass": 41793.0, "length": 375, "protein_name": "Actin, cytoplasmic 1", "gene_name": "Actg1", "organism": "Hamster", "refseq_name": "actin, cytoplasmic 2 isoform X1", "refseq_ac": [ { "id": "XP_003496930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496930", "type": "external" } ], "gene_names_uniprotkb": "Actg1", "gene_names_refseq": "Actg1", "protein_names_uniprotkb": "Actin, cytoplasmic 1; Beta-actin", "protein_names_refseq": "actin, cytoplasmic 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113830633)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 437 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) and transcript sequence (JP038734.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003496930.1. COMPLETENESS: full length., [RefSeq]; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments. Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0044305 calyx of Held;GO:0070062 extracellular exosome;GO:0045335 phagocytic vesicle;GO:0030016 myofibril;GO:0031941 filamentous actin", "go_biological_process": "GO:0051893 regulation of focal adhesion assembly;GO:0120192 tight junction assembly;GO:0010628 positive regulation of gene expression;GO:0030335 positive regulation of cell migration;GO:0090303 positive regulation of wound healing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MH88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MHC3-1", "uniprot_id": [ { "id": "A0A8C2MHC3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MHC3", "type": "external" } ], "mass": 94799.0, "length": 819, "protein_name": "Two pore calcium channel protein 1", "gene_name": "Tpcn1", "organism": "Hamster", "refseq_name": "two pore calcium channel protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003510862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510862", "type": "external" } ], "gene_names_uniprotkb": "Tpcn1", "gene_names_refseq": "Tpcn1", "protein_names_uniprotkb": "Two pore calcium channel protein 1; Voltage-dependent calcium channel protein TPC1", "protein_names_refseq": "two pore calcium channel protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614971.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Intracellular channel initially characterized as a non-selective Ca(2+)-permeable channel activated by NAADP (nicotinic acid adenine dinucleotide phosphate), it is also a voltage-gated highly-selective Na(+) channel activated directly by PI(3,5)P2 (phosphatidylinositol 3,5-bisphosphate) that senses pH changes and confers electrical excitability to organelles. Localizes to the early and recycling endosomes membranes where it plays a role in the uptake and processing of proteins and regulates organellar membrane excitability, membrane trafficking and pH homeostasis. Ion selectivity is not fixed but rather agonist-dependent and under defined ionic conditions, can be readily activated by both NAADP and PI(3,5)P2. Required for mTOR-dependent nutrient sensing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0072345 NAADP-sensitive calcium-release channel activity;GO:0042803 protein homodimerization activity;GO:0019905 syntaxin binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0015280 ligand-gated sodium channel activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane;GO:0034702 monoatomic ion channel complex;GO:0036019 endolysosome", "go_biological_process": "GO:0010508 positive regulation of autophagy;GO:0075509 endocytosis involved in viral entry into host cell", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MHC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MHJ1-1", "uniprot_id": [ { "id": "A0A8C2MHJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MHJ1", "type": "external" } ], "mass": 32662.0, "length": 286, "protein_name": "3-hydroxyanthranilate 3,4-dioxygenase", "gene_name": "Haao", "organism": "Hamster", "refseq_name": "3-hydroxyanthranilate 3,4-dioxygenase", "refseq_ac": [ { "id": "XP_003496263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496263", "type": "external" } ], "gene_names_uniprotkb": "Haao; HAAO", "gene_names_refseq": "Haao", "protein_names_uniprotkb": "3-hydroxyanthranilate 3,4-dioxygenase; 1.13.11.6; 3-HAO; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid dioxygenase; HAD", "protein_names_refseq": "3-hydroxyanthranilate 3,4-dioxygenase", "tax_id": 10029, "disease": "", "pathway": " (cge:100759566)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613615.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003496263.2. COMPLETENESS: full length., [RefSeq]; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.13.11.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.6", "type": "external" } ], "go_molecular_function": "GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity;GO:0008198 ferrous iron binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006569 L-tryptophan catabolic process;GO:0010043 response to zinc ion;GO:0070050 neuron cellular homeostasis;GO:0046686 response to cadmium ion;GO:0019805 quinolinate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MHJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MHM6-1", "uniprot_id": [ { "id": "A0A8C2MHM6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MHM6", "type": "external" } ], "mass": 98029.0, "length": 917, "protein_name": "Whirlin", "gene_name": "Whrn", "organism": "Hamster", "refseq_name": "whirlin isoform X2", "refseq_ac": [ { "id": "XP_027256075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256075", "type": "external" } ], "gene_names_uniprotkb": "Whrn", "gene_names_refseq": "Whrn", "protein_names_uniprotkb": "Whirlin", "protein_names_refseq": "whirlin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754986)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005884 actin filament;GO:0030426 growth cone;GO:0045202 synapse;GO:0001917 photoreceptor inner segment", "go_biological_process": "GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0001895 retina homeostasis;GO:0021694 cerebellar Purkinje cell layer formation;GO:0060088 auditory receptor cell stereocilium organization;GO:1990227 paranodal junction maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MHM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MI68-1", "uniprot_id": [ { "id": "A0A8C2MI68_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MI68", "type": "external" } ], "mass": 13583.0, "length": 119, "protein_name": "Stromal cell-derived factor 1", "gene_name": "Cxcl12", "organism": "Hamster", "refseq_name": "stromal cell-derived factor 1 isoform X2", "refseq_ac": [ { "id": "XP_003510829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510829", "type": "external" } ], "gene_names_uniprotkb": "Cxcl12", "gene_names_refseq": "Cxcl12", "protein_names_uniprotkb": "Stromal cell-derived factor 1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor", "protein_names_refseq": "stromal cell-derived factor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759082)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 110 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614966.1) and transcript sequence (IACG01061344.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008083 growth factor activity;GO:0008009 chemokine activity;GO:0045236 CXCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:2000669 negative regulation of dendritic cell apoptotic process;GO:0006952 defense response;GO:0006955 immune response;GO:0090026 positive regulation of monocyte chemotaxis;GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MI68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MIZ5-1", "uniprot_id": [ { "id": "A0A8C2MIZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MIZ5", "type": "external" } ], "mass": 209435.0, "length": 1878, "protein_name": "Proprotein convertase subtilisin/kexin type 5", "gene_name": "LOC100762283", "organism": "Hamster", "refseq_name": "proprotein convertase subtilisin/kexin type 5 isoform X3", "refseq_ac": [ { "id": "XP_027262357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262357", "type": "external" } ], "gene_names_uniprotkb": "LOC100762283", "gene_names_refseq": "LOC100762283", "protein_names_uniprotkb": "Proprotein convertase subtilisin/kexin type 5; Proprotein convertase 5; Proprotein convertase 6; Subtilisin/kexin-like protease PC5", "protein_names_refseq": "proprotein convertase subtilisin/kexin type 5 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762283)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0042277 peptide binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005802 trans-Golgi network;GO:0005615 extracellular space", "go_biological_process": "GO:0016486 peptide hormone processing;GO:0019058 viral life cycle;GO:0007507 heart development;GO:0001822 kidney development;GO:0048566 embryonic digestive tract development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MIZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MIQ9-1", "uniprot_id": [ { "id": "A0A8C2MIQ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MIQ9", "type": "external" } ], "mass": 71547.0, "length": 628, "protein_name": "E3 ubiquitin-protein ligase TRIM41", "gene_name": "Trim41", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase TRIM41 isoform X2", "refseq_ac": [ { "id": "XP_027283479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283479", "type": "external" } ], "gene_names_uniprotkb": "Trim41", "gene_names_refseq": "Trim41", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM41; 2.3.2.27; Tripartite motif-containing protein 41", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM41 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767959)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ligase that plays essential roles in innate antiviral response. Directly binds to influenza A virus or vesicular stomatitis virus nucleoproteins and targets them for ubiquitination and proteasomal degradation, thereby limiting viral infections. Activates the innate antiviral response by catalyzing monoubiquitination of CGAS, thereby activating CGAS. Also involved in innate antiviral response by mediating 'Lys-63'-linked polyubiquitylation of BCL10 which in turn hubs NEMO for activation of NF-kappa-B and IRF3 pathways. Catalyzes the ubiquitin-mediated degradation of other substrates including protein kinase C, ZSCAN21 or TOP3B suggesting additional roles besides its function in immune response., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0001650 fibrillar center", "go_biological_process": "GO:0051607 defense response to virus;GO:0071222 cellular response to lipopolysaccharide;GO:0071225 cellular response to muramyl dipeptide;GO:0060340 positive regulation of type I interferon-mediated signaling pathway;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MIQ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MIT4-1", "uniprot_id": [ { "id": "A0A8C2MIT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MIT4", "type": "external" } ], "mass": 56036.0, "length": 487, "protein_name": "Lysophospholipid acyltransferase 5", "gene_name": "Lpcat3", "organism": "Hamster", "refseq_name": "lysophospholipid acyltransferase 5 isoform X2", "refseq_ac": [ { "id": "XP_027284030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284030", "type": "external" } ], "gene_names_uniprotkb": "Lpcat3", "gene_names_refseq": "Lpcat3", "protein_names_uniprotkb": "Lysophospholipid acyltransferase 5; 2.3.1.23; 2.3.1.n6", "protein_names_refseq": "lysophospholipid acyltransferase 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768200)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity;GO:0071617 lysophospholipid acyltransferase activity;GO:0106262 1-acylglycerophosphoethanolamine O-acyltransferase activity;GO:0106263 1-acylglycerophosphoserine O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0090158 endoplasmic reticulum membrane organization;GO:0045540 regulation of cholesterol biosynthetic process;GO:0050728 negative regulation of inflammatory response;GO:0006656 phosphatidylcholine biosynthetic process;GO:0034379 very-low-density lipoprotein particle assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MIT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MJA4-1", "uniprot_id": [ { "id": "A0A8C2MJA4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MJA4", "type": "external" } ], "mass": 51761.0, "length": 454, "protein_name": "Bone morphogenetic protein 5", "gene_name": "Bmp5", "organism": "Hamster", "refseq_name": "bone morphogenetic protein 5", "refseq_ac": [ { "id": "XP_003495058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495058", "type": "external" } ], "gene_names_uniprotkb": "Bmp5", "gene_names_refseq": "Bmp5", "protein_names_uniprotkb": "Bone morphogenetic protein 5", "protein_names_refseq": "bone morphogenetic protein 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100763439)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0070700 BMP receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030509 BMP signaling pathway;GO:0030902 hindbrain development;GO:0048738 cardiac muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MJA4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MKP7-1", "uniprot_id": [ { "id": "A0A8C2MKP7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MKP7", "type": "external" } ], "mass": 231444.0, "length": 2110, "protein_name": "Tenascin", "gene_name": "Tnc", "organism": "Hamster", "refseq_name": "tenascin isoform X1", "refseq_ac": [ { "id": "XP_035295735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295735", "type": "external" } ], "gene_names_uniprotkb": "Tnc", "gene_names_refseq": "Tnc", "protein_names_uniprotkb": "Tenascin; Hexabrachion; Tenascin-C", "protein_names_refseq": "tenascin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754133)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0045545 syndecan binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0098966 perisynaptic extracellular matrix;GO:0005604 basement membrane;GO:0005614 interstitial matrix", "go_biological_process": "GO:0007155 cell adhesion;GO:0030155 regulation of cell adhesion;GO:0009611 response to wounding;GO:0001558 regulation of cell growth;GO:0050727 regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MKP7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MJG6-1", "uniprot_id": [ { "id": "A0A8C2MJG6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MJG6", "type": "external" } ], "mass": 100873.0, "length": 885, "protein_name": "Exosome complex component 10", "gene_name": "Exosc10", "organism": "Hamster", "refseq_name": "exosome component 10 isoform X3", "refseq_ac": [ { "id": "XP_027254010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254010", "type": "external" } ], "gene_names_uniprotkb": "Exosc10", "gene_names_refseq": "Exosc10", "protein_names_uniprotkb": "Exosome complex component 10", "protein_names_refseq": "exosome component 10 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100754929)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0003727 single-stranded RNA binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000791 euchromatin;GO:0000176 nuclear exosome (RNase complex);GO:0032040 small-subunit processome", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0006281 DNA repair;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0071044 histone mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MJG6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MJU2-1", "uniprot_id": [ { "id": "A0A8C2MJU2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MJU2", "type": "external" } ], "mass": 21457.0, "length": 192, "protein_name": "small monomeric GTPase", "gene_name": "LOC100767225", "organism": "Hamster", "refseq_name": "ras-related C3 botulinum toxin substrate 2 isoform X2", "refseq_ac": [ { "id": "XP_035295076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295076", "type": "external" } ], "gene_names_uniprotkb": "LOC100767225", "gene_names_refseq": "LOC100767225", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "ras-related C3 botulinum toxin substrate 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767225)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0019887 protein kinase regulator activity;GO:0003925 G protein activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005635 nuclear envelope;GO:0005829 cytosol;GO:0005884 actin filament;GO:0030027 lamellipodium", "go_biological_process": "GO:0007015 actin filament organization;GO:0007264 small GTPase-mediated signal transduction;GO:0043304 regulation of mast cell degranulation;GO:0010592 positive regulation of lamellipodium assembly;GO:0010810 regulation of cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MJU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MJX1-1", "uniprot_id": [ { "id": "A0A8C2MJX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MJX1", "type": "external" } ], "mass": 311920.0, "length": 2871, "protein_name": "Fibrillin-1", "gene_name": "Fbn1", "organism": "Hamster", "refseq_name": "fibrillin-1 isoform X1", "refseq_ac": [ { "id": "XP_003506292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506292", "type": "external" } ], "gene_names_uniprotkb": "Fbn1", "gene_names_refseq": "Fbn1", "protein_names_uniprotkb": "Fibrillin-1", "protein_names_refseq": "fibrillin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761283)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614219.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005604 basement membrane;GO:0001527 microfibril", "go_biological_process": "GO:0035583 sequestering of TGFbeta in extracellular matrix;GO:0007507 heart development;GO:0048286 lung alveolus development;GO:0033627 cell adhesion mediated by integrin;GO:0001501 skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MJX1-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MK35-1", "uniprot_id": [ { "id": "A0A8C2MK35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MK35", "type": "external" } ], "mass": 76203.0, "length": 683, "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "Acsl5", "organism": "Hamster", "refseq_name": "long-chain-fatty-acid--CoA ligase 5", "refseq_ac": [ { "id": "XP_007650740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650740", "type": "external" } ], "gene_names_uniprotkb": "Acsl5", "gene_names_refseq": "Acsl5", "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase; 6.2.1.15; 6.2.1.3; Acyl-CoA synthetase; Long-chain acyl-CoA synthetase", "protein_names_refseq": "long-chain-fatty-acid--CoA ligase 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100773264)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615346.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0047676 arachidonate-CoA ligase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0010747 positive regulation of long-chain fatty acid import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MK35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MK39-1", "uniprot_id": [ { "id": "A0A8C2MK39_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MK39", "type": "external" } ], "mass": 40711.0, "length": 371, "protein_name": "Homeobox protein Hox-A2", "gene_name": "Hoxa2", "organism": "Hamster", "refseq_name": "homeobox protein Hox-A2 isoform X2", "refseq_ac": [ { "id": "XP_035304899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304899", "type": "external" } ], "gene_names_uniprotkb": "Hoxa2", "gene_names_refseq": "Hoxa2", "protein_names_uniprotkb": "Homeobox protein Hox-A2", "protein_names_refseq": "homeobox protein Hox-A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761561)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0060037 pharyngeal system development;GO:0048706 embryonic skeletal system development;GO:0061061 muscle structure development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MK39-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MKB7-1", "uniprot_id": [ { "id": "A0A8C2MKB7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MKB7", "type": "external" } ], "mass": 29007.0, "length": 258, "protein_name": "Synaptosomal-associated protein 29", "gene_name": "Snap29", "organism": "Hamster", "refseq_name": "synaptosomal-associated protein 29 isoform X2", "refseq_ac": [ { "id": "XP_027269005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269005", "type": "external" } ], "gene_names_uniprotkb": "Snap29", "gene_names_refseq": "Snap29", "protein_names_uniprotkb": "Synaptosomal-associated protein 29; Golgi SNARE of 32 kDa; Soluble 29 kDa NSF attachment protein; Vesicle-membrane fusion protein SNAP-29", "protein_names_refseq": "synaptosomal-associated protein 29 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756340)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000421 autophagosome membrane;GO:0005829 cytosol;GO:0031410 cytoplasmic vesicle;GO:0098793 presynapse", "go_biological_process": "GO:0015031 protein transport;GO:0060271 cilium assembly;GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane;GO:0016082 synaptic vesicle priming;GO:0016240 autophagosome membrane docking", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MKB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MKI9-1", "uniprot_id": [ { "id": "A0A8C2MKI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MKI9", "type": "external" } ], "mass": 31639.0, "length": 282, "protein_name": "Tumor necrosis factor ligand superfamily member 6", "gene_name": "Faslg", "organism": "Hamster", "refseq_name": "tumor necrosis factor ligand superfamily member 6 isoform X1", "refseq_ac": [ { "id": "XP_003497707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497707", "type": "external" } ], "gene_names_uniprotkb": "Faslg", "gene_names_refseq": "Faslg", "protein_names_uniprotkb": "Tumor necrosis factor ligand superfamily member 6; CD95 ligand; Fas antigen ligand", "protein_names_refseq": "tumor necrosis factor ligand superfamily member 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773293)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613658.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis., [UniProtKB, UniProtKB]; Cytoplasmic form induces gene transcription inhibition., [UniProtKB, UniProtKB]; Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways. Can induce apoptosis but does not appear to be essential for this process., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0070062 extracellular exosome;GO:0060205 cytoplasmic vesicle lumen", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006955 immune response;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0016525 negative regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MKI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MKJ3-1", "uniprot_id": [ { "id": "A0A8C2MKJ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MKJ3", "type": "external" } ], "mass": 22571.0, "length": 200, "protein_name": "small monomeric GTPase", "gene_name": "Rab10", "organism": "Hamster", "refseq_name": "ras-related protein Rab-10", "refseq_ac": [ { "id": "XP_003497066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497066", "type": "external" } ], "gene_names_uniprotkb": "Rab10", "gene_names_refseq": "Rab10", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-10", "tax_id": 10029, "disease": "", "pathway": " (cge:100757662)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 152 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) and transcript sequence (JI879146.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0019003 GDP binding;GO:0031489 myosin V binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome", "go_biological_process": "GO:0071786 endoplasmic reticulum tubular network organization;GO:0097051 establishment of protein localization to endoplasmic reticulum membrane;GO:0015031 protein transport;GO:0032869 cellular response to insulin stimulus;GO:0045055 regulated exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MKJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MKQ6-1", "uniprot_id": [ { "id": "A0A8C2MKQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MKQ6", "type": "external" } ], "mass": 55447.0, "length": 491, "protein_name": "Nicotinamide phosphoribosyltransferase", "gene_name": "Nampt", "organism": "Hamster", "refseq_name": "nicotinamide phosphoribosyltransferase isoform X1", "refseq_ac": [ { "id": "XP_007647719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647719", "type": "external" } ], "gene_names_uniprotkb": "Nampt", "gene_names_refseq": "Nampt", "protein_names_uniprotkb": "Nicotinamide phosphoribosyltransferase; 2.4.2.12; NAmPRTase", "protein_names_refseq": "nicotinamide phosphoribosyltransferase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767492)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 176 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614606.1) and transcript sequence (JI893169.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.12", "type": "external" } ], "go_molecular_function": "GO:0047280 nicotinamide phosphoribosyltransferase activity;GO:0042802 identical protein binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006741 NADP+ biosynthetic process;GO:0006954 inflammatory response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032922 circadian regulation of gene expression;GO:0034355 NAD+ biosynthetic process via the salvage pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MKQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MKV0-1", "uniprot_id": [ { "id": "A0A8C2MKV0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MKV0", "type": "external" } ], "mass": 37427.0, "length": 338, "protein_name": "Citramalyl-CoA lyase, mitochondrial", "gene_name": "Clybl", "organism": "Hamster", "refseq_name": "citramalyl-CoA lyase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027244749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244749", "type": "external" } ], "gene_names_uniprotkb": "Clybl", "gene_names_refseq": "Clybl", "protein_names_uniprotkb": "Citramalyl-CoA lyase, mitochondrial; (3S)-malyl-CoA thioesterase; 2.3.3.9; 3.1.2.30; 4.1.3.25; Beta-methylmalate synthase; Citrate lyase subunit beta-like protein, mitochondrial; Malate synthase", "protein_names_refseq": "citramalyl-CoA lyase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767276)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial enzyme required to detoxify vitamin B12-poisoning metabolites. Acts as a citramalyl-CoA lyase by converting citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway, a pathway required to detoxify itaconate, a vitamin B12-poisoning metabolite. Also acts as a malyl-CoA thioesterase to detoxify malyl-CoA, a side product of citric acid cycle enzymes, which is toxic for the vitamin B12-dependent enzyme MMUT. Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. Also has very weak citramalate synthase activity in vitro., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.3.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.9", "type": "external" }, { "id": "4.1.3.25", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.25", "type": "external" }, { "id": "3.1.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.30", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0016289 acyl-CoA hydrolase activity;GO:0004474 malate synthase activity;GO:0047777 (S)-citramalyl-CoA lyase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070207 protein homotrimerization;GO:0106121 positive regulation of cobalamin metabolic process;GO:0110052 toxic metabolite repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MKV0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2ML94-1", "uniprot_id": [ { "id": "A0A8C2ML94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2ML94", "type": "external" } ], "mass": 164618.0, "length": 1500, "protein_name": "Carbamoyl-phosphate synthase [ammonia], mitochondrial", "gene_name": "Cps1", "organism": "Hamster", "refseq_name": "carbamoyl-phosphate synthase [ammonia], mitochondrial", "refseq_ac": [ { "id": "XP_027252937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252937", "type": "external" } ], "gene_names_uniprotkb": "Cps1", "gene_names_refseq": "Cps1", "protein_names_uniprotkb": "Carbamoyl-phosphate synthase [ammonia], mitochondrial; 6.3.4.16; Carbamoyl-phosphate synthetase I", "protein_names_refseq": "carbamoyl-phosphate synthase [ammonia], mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100760467)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.16", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.16", "type": "external" }, { "id": "2.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.2", "type": "external" }, { "id": "3.5.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.3", "type": "external" }, { "id": "6.3.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.5", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0004087 carbamoyl-phosphate synthase (ammonia) activity;GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0072341 modified amino acid binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005886 plasma membrane;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0046209 nitric oxide metabolic process;GO:0070409 carbamoyl phosphate biosynthetic process;GO:0071242 cellular response to ammonium ion;GO:0032496 response to lipopolysaccharide;GO:0042311 vasodilation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2ML94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MLD5-1", "uniprot_id": [ { "id": "A0A8C2MLD5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MLD5", "type": "external" } ], "mass": 21850.0, "length": 207, "protein_name": "Vascular endothelial growth factor B", "gene_name": "Vegfb", "organism": "Hamster", "refseq_name": "vascular endothelial growth factor B isoform X2", "refseq_ac": [ { "id": "XP_027264234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264234", "type": "external" } ], "gene_names_uniprotkb": "Vegfb", "gene_names_refseq": "Vegfb", "protein_names_uniprotkb": "Vascular endothelial growth factor B; VEGF-related factor", "protein_names_refseq": "vascular endothelial growth factor B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759545)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0042802 identical protein binding;GO:0008083 growth factor activity;GO:0005172 vascular endothelial growth factor receptor binding;GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0001666 response to hypoxia;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation;GO:0051781 positive regulation of cell division;GO:0048010 vascular endothelial growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MLD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MLU1-1", "uniprot_id": [ { "id": "A0A8C2MLU1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MLU1", "type": "external" } ], "mass": 33975.0, "length": 324, "protein_name": "Ribokinase", "gene_name": "Rbks", "organism": "Hamster", "refseq_name": "ribokinase isoform X2", "refseq_ac": [ { "id": "XP_027280230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280230", "type": "external" } ], "gene_names_uniprotkb": "Rbks; RBKS", "gene_names_refseq": "Rbks", "protein_names_uniprotkb": "Ribokinase; 2.7.1.15; RK", "protein_names_refseq": "ribokinase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762399)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.15", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0004747 ribokinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006098 pentose-phosphate shunt;GO:0019303 D-ribose catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MLU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MM82-1", "uniprot_id": [ { "id": "A0A8C2MM82_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MM82", "type": "external" } ], "mass": 95697.0, "length": 857, "protein_name": "Potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "organism": "Hamster", "refseq_name": "potassium voltage-gated channel subfamily B member 1 isoform X2", "refseq_ac": [ { "id": "XP_027279164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279164", "type": "external" } ], "gene_names_uniprotkb": "Kcnb1", "gene_names_refseq": "Kcnb1", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel subunit Kv2.1", "protein_names_refseq": "potassium voltage-gated channel subfamily B member 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759046)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0030424 axon;GO:0043204 perikaryon;GO:0045211 postsynaptic membrane;GO:0008076 voltage-gated potassium channel complex;GO:0042383 sarcolemma", "go_biological_process": "GO:0098900 regulation of action potential;GO:0051260 protein homooligomerization;GO:0071333 cellular response to glucose stimulus;GO:0001508 action potential;GO:0046676 negative regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MM82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MM88-1", "uniprot_id": [ { "id": "A0A8C2MM88_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MM88", "type": "external" } ], "mass": 56890.0, "length": 502, "protein_name": "Serine/threonine-protein kinase receptor", "gene_name": "LOC100774629", "organism": "Hamster", "refseq_name": "bone morphogenetic protein receptor type-1B isoform X1", "refseq_ac": [ { "id": "XP_027240684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240684", "type": "external" } ], "gene_names_uniprotkb": "LOC100774629", "gene_names_refseq": "LOC100774629", "protein_names_uniprotkb": "Serine/threonine-protein kinase receptor; 2.7.11.30", "protein_names_refseq": "bone morphogenetic protein receptor type-1B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774629)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 491 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615763.1) and transcript sequence (IACG01058421.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027240684.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005025 transforming growth factor beta receptor activity, type I;GO:0046332 SMAD binding;GO:0098821 BMP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030501 positive regulation of bone mineralization;GO:0060348 bone development;GO:0045669 positive regulation of osteoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MM88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MMB9-1", "uniprot_id": [ { "id": "A0A8C2MMB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MMB9", "type": "external" } ], "mass": 161161.0, "length": 1436, "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "Nsd3", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase NSD3 isoform X1", "refseq_ac": [ { "id": "XP_003498274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498274", "type": "external" } ], "gene_names_uniprotkb": "Nsd3", "gene_names_refseq": "Nsd3", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase NSD3; 2.1.1.370; 2.1.1.371; Nuclear SET domain-containing protein 3", "protein_names_refseq": "histone-lysine N-methyltransferase NSD3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773097)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 328 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613685.1) and transcript sequence (IACG01044521.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" }, { "id": "2.1.1.371", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.371", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046975 histone H3K36 methyltransferase activity;GO:0140537 transcription regulator activator activity;GO:0140951 histone H3K27 trimethyltransferase activity;GO:0140946 histone H3K4 dimethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005694 chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MMB9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MMI1-1", "uniprot_id": [ { "id": "A0A8C2MMI1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MMI1", "type": "external" } ], "mass": 30422.0, "length": 271, "protein_name": "Aquaporin", "gene_name": "Aqp11", "organism": "Hamster", "refseq_name": "aquaporin-11", "refseq_ac": [ { "id": "XP_035298274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298274", "type": "external" } ], "gene_names_uniprotkb": "Aqp11", "gene_names_refseq": "Aqp11", "protein_names_uniprotkb": "Aquaporin", "protein_names_refseq": "aquaporin-11", "tax_id": 10029, "disease": "", "pathway": " (cge:100768567)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Channel protein that facilitates the transport of water, glycerol and hydrogen peroxide across membrane of cell or organelles guaranteeing intracellular homeostasis in several organes like liver, kidney and brain. In situation of stress, participates in endoplasmic reticulum (ER) homeostasis by regulating redox homeostasis through the transport of hydrogen peroxide across the endoplasmic reticulum membrane thereby regulating the oxidative stress through the NADPH oxidase 2 pathway. Plays a role by maintaining an environment suitable for translation or protein foldings in the ER lumen namely by participating in the PKD1 glycosylation processing resulting in regulation of PKD1 membrane trafficking thereby preventing the accumulation of unfolding protein in ER. Plays a role in the proximal tubule function by regulating its endosomal acidification. May play a role in postnatal kidney development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity;GO:0015254 glycerol channel activity;GO:0140070 hydrogen peroxide channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0051260 protein homooligomerization;GO:0006612 protein targeting to membrane;GO:0050680 negative regulation of epithelial cell proliferation;GO:0009992 intracellular water homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MMI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MMI4-1", "uniprot_id": [ { "id": "A0A8C2MMI4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MMI4", "type": "external" } ], "mass": 64954.0, "length": 566, "protein_name": "Serine/threonine-protein kinase RIO1", "gene_name": "Riok1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase RIO1 isoform X1", "refseq_ac": [ { "id": "XP_003502051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502051", "type": "external" } ], "gene_names_uniprotkb": "Riok1", "gene_names_refseq": "Riok1", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIO1; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase RIO1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765917)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613871.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0030688 preribosome, small subunit precursor;GO:0034708 methyltransferase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:2000234 positive regulation of rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042254 ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MMI4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MMK0-1", "uniprot_id": [ { "id": "A0A8C2MMK0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MMK0", "type": "external" } ], "mass": 99379.0, "length": 927, "protein_name": "Progesterone receptor", "gene_name": "Pgr", "organism": "Hamster", "refseq_name": "progesterone receptor isoform X1", "refseq_ac": [ { "id": "XP_027270954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270954", "type": "external" } ], "gene_names_uniprotkb": "Pgr", "gene_names_refseq": "Pgr", "protein_names_uniprotkb": "Progesterone receptor; Nuclear receptor subfamily 3 group C member 3; PR", "protein_names_refseq": "progesterone receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757656)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Transrepressional activity may involve recruitment of corepressor NCOR2., [UniProtKB, UniProtKB]; Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues., [UniProtKB, UniProtKB, UniProtKB]; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor., [UniProtKB, UniProtKB]; Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0051117 ATPase binding;GO:0003707 nuclear steroid receptor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0022602 ovulation cycle process;GO:0008585 female gonad development;GO:0051457 maintenance of protein location in nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MMK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MMX0-1", "uniprot_id": [ { "id": "A0A8C2MMX0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MMX0", "type": "external" } ], "mass": 140840.0, "length": 1317, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Tnks", "organism": "Hamster", "refseq_name": "poly [ADP-ribose] polymerase tankyrase-1 isoform X1", "refseq_ac": [ { "id": "XP_016829760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829760", "type": "external" } ], "gene_names_uniprotkb": "Tnks", "gene_names_refseq": "Tnks", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "poly [ADP-ribose] polymerase tankyrase-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756523)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 512 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613748.1) and transcript sequence (IACG01074238.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016829760.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005829 cytosol;GO:0097431 mitotic spindle pole;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0070213 protein auto-ADP-ribosylation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032212 positive regulation of telomere maintenance via telomerase;GO:0070198 protein localization to chromosome, telomeric region;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MMX0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MN78-1", "uniprot_id": [ { "id": "A0A8C2MN78_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MN78", "type": "external" } ], "mass": 66934.0, "length": 592, "protein_name": "Cryptochrome-2", "gene_name": "Cry2", "organism": "Hamster", "refseq_name": "cryptochrome-2", "refseq_ac": [ { "id": "XP_027278251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278251", "type": "external" } ], "gene_names_uniprotkb": "Cry2", "gene_names_refseq": "Cry2", "protein_names_uniprotkb": "Cryptochrome-2", "protein_names_refseq": "cryptochrome-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774356)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0071949 FAD binding;GO:0003684 damaged DNA binding;GO:0000976 transcription cis-regulatory region binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:2000850 negative regulation of glucocorticoid secretion;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0042593 glucose homeostasis;GO:0032868 response to insulin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MN78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MNF1-1", "uniprot_id": [ { "id": "A0A8C2MNF1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MNF1", "type": "external" } ], "mass": 70269.0, "length": 630, "protein_name": "Transporter", "gene_name": "Slc6a4", "organism": "Hamster", "refseq_name": "sodium-dependent serotonin transporter", "refseq_ac": [ { "id": "XP_035304076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304076", "type": "external" } ], "gene_names_uniprotkb": "Slc6a4", "gene_names_refseq": "Slc6a4", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium-dependent serotonin transporter", "tax_id": 10029, "disease": "", "pathway": " (cge:100754706)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0005178 integrin binding;GO:0051378 serotonin binding;GO:0015297 antiporter activity;GO:0050998 nitric-oxide synthase binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0045121 membrane raft;GO:0010008 endosome membrane", "go_biological_process": "GO:0046621 negative regulation of organ growth;GO:0048484 enteric nervous system development;GO:0010628 positive regulation of gene expression;GO:0009636 response to toxic substance;GO:0006865 amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MNF1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MNH7-1", "uniprot_id": [ { "id": "A0A8C2MNH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MNH7", "type": "external" } ], "mass": 33568.0, "length": 310, "protein_name": "Upstream stimulatory factor 1", "gene_name": "Usf1", "organism": "Hamster", "refseq_name": "upstream stimulatory factor 1 isoform X1", "refseq_ac": [ { "id": "XP_027274781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274781", "type": "external" } ], "gene_names_uniprotkb": "Usf1", "gene_names_refseq": "Usf1", "protein_names_uniprotkb": "Upstream stimulatory factor 1; Major late transcription factor 1", "protein_names_refseq": "upstream stimulatory factor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764971)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0042826 histone deacetylase binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0019086 late viral transcription;GO:0006351 DNA-templated transcription;GO:0032869 cellular response to insulin stimulus;GO:0055088 lipid homeostasis;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MNH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MNS5-1", "uniprot_id": [ { "id": "A0A8C2MNS5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MNS5", "type": "external" } ], "mass": 67636.0, "length": 613, "protein_name": "Thioredoxin reductase 3", "gene_name": "Txnrd3", "organism": "Hamster", "refseq_name": "thioredoxin reductase 3 isoform X2", "refseq_ac": [ { "id": "XP_027284649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284649", "type": "external" } ], "gene_names_uniprotkb": "Txnrd3", "gene_names_refseq": "Txnrd3", "protein_names_uniprotkb": "Thioredoxin reductase 3; 1.8.1.9; Thioredoxin and glutathione reductase; Thioredoxin reductase TR2", "protein_names_refseq": "thioredoxin reductase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770105)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.9", "type": "external" }, { "id": "1.11.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.2", "type": "external" } ], "go_molecular_function": "GO:0004791 thioredoxin-disulfide reductase (NADPH) activity;GO:0050660 flavin adenine dinucleotide binding;GO:0004362 glutathione-disulfide reductase (NADPH) activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0034599 cellular response to oxidative stress;GO:0045454 cell redox homeostasis;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MNS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F842-1", "uniprot_id": [ { "id": "A0A9J7F842_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F842", "type": "external" } ], "mass": 238466.0, "length": 2110, "protein_name": "1-phosphatidylinositol 3-phosphate 5-kinase", "gene_name": "Pikfyve", "organism": "Hamster", "refseq_name": "1-phosphatidylinositol 3-phosphate 5-kinase isoform X1", "refseq_ac": [ { "id": "XP_007645646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645646", "type": "external" } ], "gene_names_uniprotkb": "Pikfyve", "gene_names_refseq": "Pikfyve", "protein_names_uniprotkb": "1-phosphatidylinositol 3-phosphate 5-kinase; 2.7.1.150; 2.7.11.1; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; Serine-protein kinase PIKFYVE", "protein_names_refseq": "1-phosphatidylinositol 3-phosphate 5-kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758487)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614305.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" } ], "go_molecular_function": "GO:0052810 1-phosphatidylinositol-5-kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0045121 membrane raft;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0034504 protein localization to nucleus;GO:0032438 melanosome organization;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F842-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MP33-1", "uniprot_id": [ { "id": "A0A8C2MP33_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MP33", "type": "external" } ], "mass": 316856.0, "length": 2920, "protein_name": "Cadherin EGF LAG seven-pass G-type receptor 2", "gene_name": "Celsr2", "organism": "Hamster", "refseq_name": "cadherin EGF LAG seven-pass G-type receptor 2 isoform X2", "refseq_ac": [ { "id": "XP_027251302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251302", "type": "external" } ], "gene_names_uniprotkb": "Celsr2", "gene_names_refseq": "Celsr2", "protein_names_uniprotkb": "Cadherin EGF LAG seven-pass G-type receptor 2; Multiple epidermal growth factor-like domains protein 3", "protein_names_refseq": "cadherin EGF LAG seven-pass G-type receptor 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751011)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor that may have an important role in cell/cell signaling during nervous system formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0001764 neuron migration;GO:0006355 regulation of DNA-templated transcription;GO:0016055 Wnt signaling pathway;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MP33-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPA4-1", "uniprot_id": [ { "id": "A0A8C2MPA4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPA4", "type": "external" } ], "mass": 55745.0, "length": 485, "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "gene_name": "Pacsin2", "organism": "Hamster", "refseq_name": "protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "refseq_ac": [ { "id": "XP_016833948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833948", "type": "external" } ], "gene_names_uniprotkb": "Pacsin2", "gene_names_refseq": "Pacsin2", "protein_names_uniprotkb": "Protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "protein_names_refseq": "protein kinase C and casein kinase substrate in neurons protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767688)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614471.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0008092 cytoskeletal protein binding;GO:0016301 kinase activity;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005769 early endosome;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005912 adherens junction", "go_biological_process": "GO:0072584 caveolin-mediated endocytosis;GO:0030100 regulation of endocytosis;GO:0030036 actin cytoskeleton organization;GO:0036010 protein localization to endosome;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPA4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPB0-1", "uniprot_id": [ { "id": "A0A8C2MPB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPB0", "type": "external" } ], "mass": 24650.0, "length": 218, "protein_name": "Sodium channel regulatory subunit beta-1", "gene_name": "Scn1b", "organism": "Hamster", "refseq_name": "sodium channel subunit beta-1 isoform X2", "refseq_ac": [ { "id": "XP_035305428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305428", "type": "external" } ], "gene_names_uniprotkb": "Scn1b", "gene_names_refseq": "Scn1b", "protein_names_uniprotkb": "Sodium channel regulatory subunit beta-1", "protein_names_refseq": "sodium channel subunit beta-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758608)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulatory subunit of multiple voltage-gated sodium (Nav) channels directly mediating the depolarization of excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operate by switching between closed and open conformations depending on the voltage difference across the membrane. In the open conformation they allow Na(+) ions to selectively pass through the pore, along their electrochemical gradient. The influx of Na+ ions provokes membrane depolarization, initiating the propagation of electrical signals throughout cells and tissues. The accessory beta subunits participate in localization and functional modulation of the Nav channels. Modulates the activity of SCN1A/Nav1.1, SCN2A/Nav1.2, SCN3A/Nav1.3, SCN4A/Nav1.4, SCN5A/Nav1.5, SCN8A/Nav1.6, SCN9A/Nav1.7 and SCN10A/Nav1.8., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019871 sodium channel inhibitor activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0043204 perikaryon;GO:0014704 intercalated disc;GO:0030315 T-tubule;GO:0033268 node of Ranvier;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0086091 regulation of heart rate by cardiac conduction;GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization;GO:0035725 sodium ion transmembrane transport;GO:0010765 positive regulation of sodium ion transport;GO:0086002 cardiac muscle cell action potential involved in contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPE8-1", "uniprot_id": [ { "id": "A0A8C2MPE8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPE8", "type": "external" } ], "mass": 98650.0, "length": 882, "protein_name": "[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B", "gene_name": "Kmt5b", "organism": "Hamster", "refseq_name": "histone-lysine N-methyltransferase KMT5B isoform X3", "refseq_ac": [ { "id": "XP_027264565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264565", "type": "external" } ], "gene_names_uniprotkb": "Kmt5b", "gene_names_refseq": "Kmt5b", "protein_names_uniprotkb": "[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; 2.1.1.361; 2.1.1.362; [histone H4]-lysine20 N-methyltransferase KMT5B", "protein_names_refseq": "histone-lysine N-methyltransferase KMT5B isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761878)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:1904047 S-adenosyl-L-methionine binding;GO:0140941 histone H4K20me methyltransferase activity;GO:0140944 histone H4K20 monomethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0000779 condensed chromosome, centromeric region", "go_biological_process": "GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0007517 muscle organ development;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPL5-1", "uniprot_id": [ { "id": "A0A8C2MPL5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPL5", "type": "external" } ], "mass": 515718.0, "length": 4487, "protein_name": "Dynein axonemal heavy chain 11", "gene_name": "Dnah11", "organism": "Hamster", "refseq_name": "dynein heavy chain 11, axonemal isoform X2", "refseq_ac": [ { "id": "XP_027272227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272227", "type": "external" } ], "gene_names_uniprotkb": "Dnah11", "gene_names_refseq": "Dnah11", "protein_names_uniprotkb": "Dynein axonemal heavy chain 11; Axonemal beta dynein heavy chain 11; Ciliary dynein heavy chain 11", "protein_names_refseq": "dynein heavy chain 11, axonemal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770442)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Force generating protein required for cilia beating in respiratory epithelia. Produces force towards the minus ends of microtubules. Key component of dynein, a family of motor proteins essential for movement along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of cilia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0030286 dynein complex;GO:0097729 9+2 motile cilium;GO:0097728 9+0 motile cilium;GO:0120134 proximal portion of axoneme", "go_biological_process": "GO:0003341 cilium movement;GO:0120229 protein localization to motile cilium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPL5-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPQ5-1", "uniprot_id": [ { "id": "A0A8C2MPQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPQ5", "type": "external" } ], "mass": 103197.0, "length": 920, "protein_name": "Protein O-GlcNAcase", "gene_name": "Oga", "organism": "Hamster", "refseq_name": "protein O-GlcNAcase isoform X2", "refseq_ac": [ { "id": "XP_027262966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262966", "type": "external" } ], "gene_names_uniprotkb": "Oga", "gene_names_refseq": "Oga", "protein_names_uniprotkb": "Protein O-GlcNAcase; 3.2.1.169; Beta-N-acetylhexosaminidase; Beta-hexosaminidase; Bifunctional protein NCOAT; Meningioma-expressed antigen 5; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase", "protein_names_refseq": "protein O-GlcNAcase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751586)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Deglycosylates a large and diverse number of proteins, such as CRYAB, ELK1, GSDMD, LMNB1 and TAB1. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.169", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.169", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0016231 beta-N-acetylglucosaminidase activity;GO:0102571 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006044 N-acetylglucosamine metabolic process;GO:0009100 glycoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPT1-1", "uniprot_id": [ { "id": "A0A8C2MPT1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPT1", "type": "external" } ], "mass": 138007.0, "length": 1453, "protein_name": "Collagen alpha-1(I) chain", "gene_name": "Col1a1", "organism": "Hamster", "refseq_name": "collagen alpha-1(I) chain", "refseq_ac": [ { "id": "XP_003504008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504008", "type": "external" } ], "gene_names_uniprotkb": "Col1a1", "gene_names_refseq": "Col1a1", "protein_names_uniprotkb": "Collagen alpha-1(I) chain", "protein_names_refseq": "collagen alpha-1(I) chain", "tax_id": 10029, "disease": "", "pathway": " (cge:100759814)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614015.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0005201 extracellular matrix structural constituent;GO:0048407 platelet-derived growth factor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005584 collagen type I trimer", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0007601 visual perception;GO:0030199 collagen fibril organization;GO:0045893 positive regulation of DNA-templated transcription;GO:0001568 blood vessel development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPT1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MPY4-1", "uniprot_id": [ { "id": "A0A8C2MPY4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MPY4", "type": "external" } ], "mass": 261035.0, "length": 2339, "protein_name": "Proto-oncogene tyrosine-protein kinase ROS", "gene_name": "Ros1", "organism": "Hamster", "refseq_name": "proto-oncogene tyrosine-protein kinase ROS", "refseq_ac": [ { "id": "XP_003507024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507024", "type": "external" } ], "gene_names_uniprotkb": "Ros1", "gene_names_refseq": "Ros1", "protein_names_uniprotkb": "Proto-oncogene tyrosine-protein kinase ROS; 2.7.10.1; Proto-oncogene c-Ros-1; Proto-oncogene c-Ros; Receptor tyrosine kinase c-ros oncogene 1; c-Ros receptor tyrosine kinase", "protein_names_refseq": "proto-oncogene tyrosine-protein kinase ROS", "tax_id": 10029, "disease": "", "pathway": " (cge:100760611)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614311.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019903 protein phosphatase binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0070372 regulation of ERK1 and ERK2 cascade;GO:0032006 regulation of TOR signaling;GO:0002066 columnar/cuboidal epithelial cell development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MPY4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQ42-1", "uniprot_id": [ { "id": "A0A8C2MQ42_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQ42", "type": "external" } ], "mass": 107483.0, "length": 960, "protein_name": "Cyclin-dependent kinase-like 5", "gene_name": "Cdkl5", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase-like 5", "refseq_ac": [ { "id": "XP_027288570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288570", "type": "external" } ], "gene_names_uniprotkb": "Cdkl5", "gene_names_refseq": "Cdkl5", "protein_names_uniprotkb": "Cyclin-dependent kinase-like 5; 2.7.11.22", "protein_names_refseq": "cyclin-dependent kinase-like 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100751248)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates phosphorylation of MECP2. May regulate ciliogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0032839 dendrite cytoplasm;GO:0036064 ciliary basal body", "go_biological_process": "GO:0050804 modulation of chemical synaptic transmission;GO:0045773 positive regulation of axon extension;GO:1902017 regulation of cilium assembly;GO:0050773 regulation of dendrite development;GO:0099175 regulation of postsynapse organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQ42-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQ61-1", "uniprot_id": [ { "id": "A0A8C2MQ61_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQ61", "type": "external" } ], "mass": 90175.0, "length": 803, "protein_name": "E3 ubiquitin-protein ligase UHRF", "gene_name": "Uhrf2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase UHRF2 isoform X2", "refseq_ac": [ { "id": "XP_027262218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262218", "type": "external" } ], "gene_names_uniprotkb": "Uhrf2", "gene_names_refseq": "Uhrf2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase UHRF; 2.3.2.27; RING-type E3 ubiquitin transferase UHRF; Ubiquitin-like PHD and RING finger domain-containing protein; Ubiquitin-like-containing PHD and RING finger domains protein", "protein_names_refseq": "E3 ubiquitin-protein ligase UHRF2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762841)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0030154 cell differentiation;GO:0051865 protein autoubiquitination;GO:0051726 regulation of cell cycle;GO:0044027 negative regulation of gene expression via chromosomal CpG island methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQ61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQA7-1", "uniprot_id": [ { "id": "A0A8C2MQA7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQA7", "type": "external" } ], "mass": 105883.0, "length": 955, "protein_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "gene_name": "Mdga1", "organism": "Hamster", "refseq_name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027250214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250214", "type": "external" } ], "gene_names_uniprotkb": "Mdga1", "gene_names_refseq": "Mdga1", "protein_names_uniprotkb": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1", "protein_names_refseq": "MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751858)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for radial migration of cortical neurons in the superficial layer of the neocortex. Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0050808 synapse organization;GO:0001764 neuron migration;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0099179 regulation of synaptic membrane adhesion;GO:1905606 regulation of presynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQA7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQN4-1", "uniprot_id": [ { "id": "A0A8C2MQN4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQN4", "type": "external" } ], "mass": 49949.0, "length": 466, "protein_name": "Transcription factor SOX-10", "gene_name": "Sox10", "organism": "Hamster", "refseq_name": "transcription factor SOX-10", "refseq_ac": [ { "id": "XP_027259784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259784", "type": "external" } ], "gene_names_uniprotkb": "Sox10", "gene_names_refseq": "Sox10", "protein_names_uniprotkb": "Transcription factor SOX-10", "protein_names_refseq": "transcription factor SOX-10", "tax_id": 10029, "disease": "", "pathway": " (cge:100754443)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0048484 enteric nervous system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0022010 central nervous system myelination;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQX1-1", "uniprot_id": [ { "id": "A0A8C2MQX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQX1", "type": "external" } ], "mass": 96932.0, "length": 874, "protein_name": "Endothelial PAS domain-containing protein 1 isoform X2", "gene_name": "Epas1", "organism": "Hamster", "refseq_name": "endothelial PAS domain-containing protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027273773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273773", "type": "external" } ], "gene_names_uniprotkb": "Epas1", "gene_names_refseq": "Epas1", "protein_names_uniprotkb": "Endothelial PAS domain-containing protein 1 isoform X2", "protein_names_refseq": "endothelial PAS domain-containing protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771160)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0001223 transcription coactivator binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0072359 circulatory system development;GO:0035295 tube development;GO:0071456 cellular response to hypoxia;GO:0042789 mRNA transcription by RNA polymerase II;GO:0048625 myoblast fate commitment", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQX2-1", "uniprot_id": [ { "id": "A0A8C2MQX2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQX2", "type": "external" } ], "mass": 152467.0, "length": 1466, "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "Nup153", "organism": "Hamster", "refseq_name": "nuclear pore complex protein Nup153 isoform X1", "refseq_ac": [ { "id": "XP_007644193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644193", "type": "external" } ], "gene_names_uniprotkb": "Nup153", "gene_names_refseq": "Nup153", "protein_names_uniprotkb": "Nuclear pore complex protein Nup153; 153 kDa nucleoporin; Nucleoporin Nup153", "protein_names_refseq": "nuclear pore complex protein Nup153 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761805)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 135 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613609.1) and transcript sequence (JI875944.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0043495 protein-membrane adaptor activity;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0031965 nuclear membrane;GO:0034399 nuclear periphery;GO:0042405 nuclear inclusion body", "go_biological_process": "GO:0046832 negative regulation of RNA export from nucleus;GO:1990000 amyloid fibril formation;GO:0051292 nuclear pore complex assembly;GO:0051028 mRNA transport;GO:0006405 RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQX2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQX8-1", "uniprot_id": [ { "id": "A0A8C2MQX8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQX8", "type": "external" } ], "mass": 123829.0, "length": 1134, "protein_name": "Vinculin", "gene_name": "Vcl", "organism": "Hamster", "refseq_name": "vinculin isoform X2", "refseq_ac": [ { "id": "XP_003496777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496777", "type": "external" } ], "gene_names_uniprotkb": "Vcl", "gene_names_refseq": "Vcl", "protein_names_uniprotkb": "Vinculin; Metavinculin", "protein_names_refseq": "vinculin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759958)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613632.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031625 ubiquitin protein ligase binding;GO:0005198 structural molecule activity;GO:0002162 dystroglycan binding;GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0061826 podosome ring;GO:0005912 adherens junction;GO:0005925 focal adhesion;GO:0048471 perinuclear region of cytoplasm;GO:0042383 sarcolemma", "go_biological_process": "GO:0043297 apical junction assembly;GO:0051893 regulation of focal adhesion assembly;GO:1903140 regulation of establishment of endothelial barrier;GO:0034394 protein localization to cell surface;GO:0034333 adherens junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQX8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MQX9-1", "uniprot_id": [ { "id": "A0A8C2MQX9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MQX9", "type": "external" } ], "mass": 92540.0, "length": 850, "protein_name": "MICAL-like protein 1", "gene_name": "Micall1", "organism": "Hamster", "refseq_name": "MICAL-like protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027259783", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259783", "type": "external" } ], "gene_names_uniprotkb": "Micall1", "gene_names_refseq": "Micall1", "protein_names_uniprotkb": "MICAL-like protein 1", "protein_names_refseq": "MICAL-like protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756473)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0008093 cytoskeletal anchor activity;GO:0031267 small GTPase binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005912 adherens junction;GO:0031902 late endosome membrane;GO:0055038 recycling endosome membrane;GO:0005814 centriole", "go_biological_process": "GO:0015031 protein transport;GO:0031175 neuron projection development;GO:0006612 protein targeting to membrane;GO:0060271 cilium assembly;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MQX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MR08-1", "uniprot_id": [ { "id": "A0A8C2MR08_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MR08", "type": "external" } ], "mass": 144818.0, "length": 1314, "protein_name": "Serine/threonine-protein kinase 36", "gene_name": "Stk36", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase 36", "refseq_ac": [ { "id": "XP_007646393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646393", "type": "external" } ], "gene_names_uniprotkb": "Stk36", "gene_names_refseq": "Stk36", "protein_names_uniprotkb": "Serine/threonine-protein kinase 36; 2.7.11.1; Fused homolog", "protein_names_refseq": "serine/threonine-protein kinase 36", "tax_id": 10029, "disease": "", "pathway": " (cge:100771030)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614410.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0001222 transcription corepressor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005930 axoneme", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0009791 post-embryonic development;GO:0007224 smoothened signaling pathway;GO:0035082 axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MR08-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MRK2-1", "uniprot_id": [ { "id": "A0A8C2MRK2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MRK2", "type": "external" } ], "mass": 29558.0, "length": 262, "protein_name": "Lysosomal-associated transmembrane protein 5 isoform X2", "gene_name": "Laptm5", "organism": "Hamster", "refseq_name": "lysosomal-associated transmembrane protein 5 isoform X2", "refseq_ac": [ { "id": "XP_027255264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255264", "type": "external" } ], "gene_names_uniprotkb": "Laptm5", "gene_names_refseq": "Laptm5", "protein_names_uniprotkb": "Lysosomal-associated transmembrane protein 5 isoform X2", "protein_names_refseq": "lysosomal-associated transmembrane protein 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766375)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane;GO:0030133 transport vesicle", "go_biological_process": "GO:2000646 positive regulation of receptor catabolic process;GO:0032703 negative regulation of interleukin-2 production;GO:0097214 positive regulation of lysosomal membrane permeability;GO:0043410 positive regulation of MAPK cascade;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MRK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MRM8-1", "uniprot_id": [ { "id": "A0A8C2MRM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MRM8", "type": "external" } ], "mass": 70739.0, "length": 637, "protein_name": "Neuroendocrine convertase 2", "gene_name": "Pcsk2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: neuroendocrine convertase 2 isoform X1", "refseq_ac": [ { "id": "XP_003508161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508161", "type": "external" } ], "gene_names_uniprotkb": "Pcsk2", "gene_names_refseq": "Pcsk2", "protein_names_uniprotkb": "Neuroendocrine convertase 2; 3.4.21.94; KEX2-like endoprotease 2; Prohormone convertase 2; Proprotein convertase 2", "protein_names_refseq": "LOW QUALITY PROTEIN: neuroendocrine convertase 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771130)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614479.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0034774 secretory granule lumen;GO:0043005 neuron projection;GO:0030133 transport vesicle", "go_biological_process": "GO:0007399 nervous system development;GO:0016540 protein autoprocessing;GO:0034230 enkephalin processing;GO:0030070 insulin processing;GO:0016486 peptide hormone processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MRM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MRW3-1", "uniprot_id": [ { "id": "A0A8C2MRW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MRW3", "type": "external" } ], "mass": 134043.0, "length": 1176, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp11b", "organism": "Hamster", "refseq_name": "probable phospholipid-transporting ATPase IF isoform X3", "refseq_ac": [ { "id": "XP_027247793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247793", "type": "external" } ], "gene_names_uniprotkb": "Atp11b", "gene_names_refseq": "Atp11b", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "probable phospholipid-transporting ATPase IF isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773257)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes. May contribute to the maintenance of membrane lipid asymmetry in endosome compartment., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0045332 phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MRW3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MS28-1", "uniprot_id": [ { "id": "A0A8C2MS28_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MS28", "type": "external" } ], "mass": 53813.0, "length": 489, "protein_name": "Metal cation symporter ZIP14", "gene_name": "Slc39a14", "organism": "Hamster", "refseq_name": "metal cation symporter ZIP14 isoform X2", "refseq_ac": [ { "id": "XP_007645724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645724", "type": "external" } ], "gene_names_uniprotkb": "Slc39a14", "gene_names_refseq": "Slc39a14", "protein_names_uniprotkb": "Metal cation symporter ZIP14; Solute carrier family 39 member 14; Zrt- and Irt-like protein 14", "protein_names_refseq": "metal cation symporter ZIP14 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613613.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0140410 monoatomic cation:bicarbonate symporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0030003 intracellular monoatomic cation homeostasis;GO:0071578 zinc ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MS28-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QM19-1", "uniprot_id": [ { "id": "A0A8C2QM19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QM19", "type": "external" } ], "mass": 69209.0, "length": 633, "protein_name": "ATP-dependent clpX-like chaperone, mitochondrial", "gene_name": "Clpx", "organism": "Hamster", "refseq_name": "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_016833451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833451", "type": "external" } ], "gene_names_uniprotkb": "Clpx", "gene_names_refseq": "Clpx", "protein_names_uniprotkb": "ATP-dependent clpX-like chaperone, mitochondrial; 3.6.4.10; ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "protein_names_refseq": "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774494)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 28 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614337.1) and transcript sequence (JI889501.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent chaperone that functions as an unfoldase. As part of the ClpXP protease complex, it recognizes specific protein substrates, unfolds them using energy derived from ATP hydrolysis, and then translocates them to the proteolytic subunit (CLPP) of the ClpXP complex for degradation. Thanks to its chaperone activity, it also functions in the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. This chaperone is also involved in the control of mtDNA nucleoid distribution, by regulating mitochondrial transcription factor A (TFAM) activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0046983 protein dimerization activity;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0042645 mitochondrial nucleoid;GO:0009841 mitochondrial endopeptidase Clp complex", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process;GO:0006457 protein folding;GO:0046034 ATP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QM19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MSP9-1", "uniprot_id": [ { "id": "A0A8C2MSP9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MSP9", "type": "external" } ], "mass": 177843.0, "length": 1551, "protein_name": "Dual oxidase 1", "gene_name": "Duox1", "organism": "Hamster", "refseq_name": "dual oxidase 1 isoform X2", "refseq_ac": [ { "id": "XP_027277793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277793", "type": "external" } ], "gene_names_uniprotkb": "Duox1", "gene_names_refseq": "Duox1", "protein_names_uniprotkb": "Dual oxidase 1; 1.6.3.1", "protein_names_refseq": "dual oxidase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774391)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.1", "type": "external" }, { "id": "1.6.99.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.99.1", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.14.13.225", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.225", "type": "external" }, { "id": "1.14.13.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.8", "type": "external" } ], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0071949 FAD binding;GO:0005509 calcium ion binding;GO:0020037 heme binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0031252 cell leading edge;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0042335 cuticle development;GO:0006979 response to oxidative stress;GO:0090303 positive regulation of wound healing;GO:0042446 hormone biosynthetic process;GO:0050665 hydrogen peroxide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MSP9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MST7-1", "uniprot_id": [ { "id": "A0A8C2MST7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MST7", "type": "external" } ], "mass": 75027.0, "length": 709, "protein_name": "Eomesodermin homolog isoform X2", "gene_name": "Eomes", "organism": "Hamster", "refseq_name": "eomesodermin homolog isoform X2", "refseq_ac": [ { "id": "XP_027271139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271139", "type": "external" } ], "gene_names_uniprotkb": "Eomes", "gene_names_refseq": "Eomes", "protein_names_uniprotkb": "Eomesodermin homolog isoform X2", "protein_names_refseq": "eomesodermin homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753878)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0048708 astrocyte differentiation;GO:0001714 endodermal cell fate specification;GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response;GO:0060706 cell differentiation involved in embryonic placenta development;GO:0060809 mesodermal to mesenchymal transition involved in gastrulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MST7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MT39-1", "uniprot_id": [ { "id": "A0A8C2MT39_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MT39", "type": "external" } ], "mass": 74160.0, "length": 664, "protein_name": "E3 ubiquitin-protein ligase CHFR", "gene_name": "Chfr", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase CHFR isoform X1", "refseq_ac": [ { "id": "XP_007640567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640567", "type": "external" } ], "gene_names_uniprotkb": "Chfr", "gene_names_refseq": "Chfr", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase CHFR; 2.3.2.27; Checkpoint with forkhead and RING finger domains protein; RING-type E3 ubiquitin transferase CHFR", "protein_names_refseq": "E3 ubiquitin-protein ligase CHFR isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771287)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613859.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation. May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000166 nucleotide binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0016605 PML body", "go_biological_process": "GO:0051301 cell division;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0044818 mitotic G2/M transition checkpoint;GO:0044779 meiotic spindle checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MT39-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MT51-1", "uniprot_id": [ { "id": "A0A8C2MT51_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MT51", "type": "external" } ], "mass": 25207.0, "length": 224, "protein_name": "Charged multivesicular body protein 3 isoform X1", "gene_name": "LOC100770826", "organism": "Hamster", "refseq_name": "charged multivesicular body protein 3 isoform X1", "refseq_ac": [ { "id": "XP_003503963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503963", "type": "external" } ], "gene_names_uniprotkb": "LOC100770826", "gene_names_refseq": "LOC100770826", "protein_names_uniprotkb": "Charged multivesicular body protein 3 isoform X1", "protein_names_refseq": "charged multivesicular body protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770826)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614012.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031210 phosphatidylcholine binding;GO:1990381 ubiquitin-specific protease binding;GO:0180020 membrane bending activity", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005828 kinetochore microtubule;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0000776 kinetochore", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0010824 regulation of centrosome duplication;GO:0031468 nuclear membrane reassembly;GO:0039702 viral budding via host ESCRT complex;GO:0061763 multivesicular body-lysosome fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MT51-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MTI5-1", "uniprot_id": [ { "id": "A0A8C2MTI5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MTI5", "type": "external" } ], "mass": 137860.0, "length": 1236, "protein_name": "Protein Jumonji", "gene_name": "Jarid2", "organism": "Hamster", "refseq_name": "protein Jumonji isoform X2", "refseq_ac": [ { "id": "XP_027266255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266255", "type": "external" } ], "gene_names_uniprotkb": "Jarid2", "gene_names_refseq": "Jarid2", "protein_names_uniprotkb": "Protein Jumonji; Jumonji/ARID domain-containing protein 2", "protein_names_refseq": "protein Jumonji isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765016)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts as an accessory subunit for the core PRC2 (Polycomb repressive complex 2) complex, which mediates histone H3K27 (H3K27me3) trimethylation on chromatin. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, thereby playing a key role in stem cell differentiation and normal embryonic development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling. Does not have histone demethylase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061649 ubiquitin-modified histone reader activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0043130 ubiquitin binding;GO:0046976 histone H3K27 methyltransferase activity", "go_cellular_component": "GO:0000785 chromatin;GO:0035098 ESC/E(Z) complex;GO:1990904 ribonucleoprotein complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0048731 system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0048863 stem cell differentiation;GO:0140718 facultative heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MTI5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MTI7-1", "uniprot_id": [ { "id": "A0A8C2MTI7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MTI7", "type": "external" } ], "mass": 65804.0, "length": 586, "protein_name": "dual-specificity kinase", "gene_name": "Dyrk3", "organism": "Hamster", "refseq_name": "dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X2", "refseq_ac": [ { "id": "XP_027273505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273505", "type": "external" } ], "gene_names_uniprotkb": "Dyrk3", "gene_names_refseq": "Dyrk3", "protein_names_uniprotkb": "dual-specificity kinase; 2.7.12.1", "protein_names_refseq": "dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761931)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0016607 nuclear speck;GO:0010494 cytoplasmic stress granule;GO:0000242 pericentriolar material;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0030218 erythrocyte differentiation;GO:0035063 nuclear speck organization;GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:1903432 regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MTI7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MTJ8-1", "uniprot_id": [ { "id": "A0A8C2MTJ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MTJ8", "type": "external" } ], "mass": 49737.0, "length": 447, "protein_name": "D(3) dopamine receptor", "gene_name": "Drd3", "organism": "Hamster", "refseq_name": "D(3) dopamine receptor isoform X1", "refseq_ac": [ { "id": "XP_003497913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497913", "type": "external" } ], "gene_names_uniprotkb": "Drd3", "gene_names_refseq": "Drd3", "protein_names_uniprotkb": "D(3) dopamine receptor; Dopamine D3 receptor", "protein_names_refseq": "D(3) dopamine receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769070)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613667.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dopamine receptor that is primarily expressed in limbic areas of the brain and is involved in the modulation of cognitive, emotional, and endocrine functions. Plays a key role in regulating neuronal signaling pathways associated with motivation, reward, and behavior. Coupled to G(i)/G(o) proteins; activation leads to inhibition of adenylate cyclase and decreased intracellular cAMP levels. Involved in the control of locomotor activity and implicated in several neuropsychiatric disorders, including schizophrenia and substance use disorders. Promotes cell proliferation through MAP kinase signaling. Also involved in autophagy regulation: receptor activation stimulates AMPK, which phosphorylates RPTOR and enhances its interaction with MTOR, thereby inhibiting MTORC1 signaling and its downstream target RPS6KB1. This leads to activation of ULK1 and initiation of the autophagy cascade. Forms heterotetramers with DRD1 to potentiate beta-arrestin recruitment and mediate locomotor activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0034776 response to histamine;GO:0050709 negative regulation of protein secretion;GO:0060158 phospholipase C-activating dopamine receptor signaling pathway;GO:0006874 intracellular calcium ion homeostasis;GO:0014059 regulation of dopamine secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MTJ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MTL9-1", "uniprot_id": [ { "id": "A0A8C2MTL9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MTL9", "type": "external" } ], "mass": 135453.0, "length": 1237, "protein_name": "Glutamate receptor", "gene_name": "Grin2c", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, NMDA 2C isoform X3", "refseq_ac": [ { "id": "XP_035303075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303075", "type": "external" } ], "gene_names_uniprotkb": "Grin2c", "gene_names_refseq": "Grin2c", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, NMDA 2C isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100758804)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005261 monoatomic cation channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0004972 NMDA glutamate receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0017146 NMDA selective glutamate receptor complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0048167 regulation of synaptic plasticity;GO:0097553 calcium ion transmembrane import into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MTL9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MU79-1", "uniprot_id": [ { "id": "A0A8C2MU79_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MU79", "type": "external" } ], "mass": 109538.0, "length": 963, "protein_name": "Kinesin-like protein", "gene_name": "Kif5b", "organism": "Hamster", "refseq_name": "kinesin-1 heavy chain isoform X2", "refseq_ac": [ { "id": "XP_027261276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261276", "type": "external" } ], "gene_names_uniprotkb": "Kif5b", "gene_names_refseq": "Kif5b", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-1 heavy chain isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774173)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005874 microtubule;GO:0035253 ciliary rootlet;GO:0043005 neuron projection;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0032230 positive regulation of synaptic transmission, GABAergic;GO:0043268 positive regulation of potassium ion transport;GO:1903078 positive regulation of protein localization to plasma membrane;GO:0032418 lysosome localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MU79-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MUJ3-1", "uniprot_id": [ { "id": "A0A8C2MUJ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MUJ3", "type": "external" } ], "mass": 26743.0, "length": 232, "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "gene_name": "Vti1b", "organism": "Hamster", "refseq_name": "vesicle transport through interaction with t-SNAREs homolog 1B", "refseq_ac": [ { "id": "XP_027274175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274175", "type": "external" } ], "gene_names_uniprotkb": "Vti1b", "gene_names_refseq": "Vti1b", "protein_names_uniprotkb": "Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1", "protein_names_refseq": "vesicle transport through interaction with t-SNAREs homolog 1B", "tax_id": 10029, "disease": "", "pathway": " (cge:100760166)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019869 chloride channel inhibitor activity;GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016236 macroautophagy;GO:0042147 retrograde transport, endosome to Golgi;GO:1903076 regulation of protein localization to plasma membrane;GO:0048280 vesicle fusion with Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MUJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MUQ5-1", "uniprot_id": [ { "id": "A0A8C2MUQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MUQ5", "type": "external" } ], "mass": 44006.0, "length": 386, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mapkapk2", "organism": "Hamster", "refseq_name": "MAP kinase-activated protein kinase 2 isoform X2", "refseq_ac": [ { "id": "XP_027273507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273507", "type": "external" } ], "gene_names_uniprotkb": "Mapkapk2", "gene_names_refseq": "Mapkapk2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "MAP kinase-activated protein kinase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762218)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006954 inflammatory response;GO:0032496 response to lipopolysaccharide;GO:0000165 MAPK cascade;GO:0006974 DNA damage response;GO:0032675 regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MUQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MV03-1", "uniprot_id": [ { "id": "A0A8C2MV03_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MV03", "type": "external" } ], "mass": 40324.0, "length": 355, "protein_name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "gene_name": "Abhd4", "organism": "Hamster", "refseq_name": "(Lyso)-N-acylphosphatidylethanolamine lipase isoform X1", "refseq_ac": [ { "id": "XP_003506166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506166", "type": "external" } ], "gene_names_uniprotkb": "Abhd4", "gene_names_refseq": "Abhd4", "protein_names_uniprotkb": "(Lyso)-N-acylphosphatidylethanolamine lipase; Alpha/beta hydrolase domain-containing protein 4; Alpha/beta-hydrolase 4", "protein_names_refseq": "(Lyso)-N-acylphosphatidylethanolamine lipase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767680)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614213.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" } ], "go_molecular_function": "GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0004622 phosphatidylcholine lysophospholipase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005811 lipid droplet", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0055088 lipid homeostasis;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MV03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MV87-1", "uniprot_id": [ { "id": "A0A8C2MV87_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MV87", "type": "external" } ], "mass": 12740.0, "length": 113, "protein_name": "RING-box protein 2", "gene_name": "Rnf7", "organism": "Hamster", "refseq_name": "RING-box protein 2 isoform X2", "refseq_ac": [ { "id": "XP_027266714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266714", "type": "external" } ], "gene_names_uniprotkb": "Rnf7", "gene_names_refseq": "Rnf7", "protein_names_uniprotkb": "RING-box protein 2; 2.3.2.27; 2.3.2.32; RING finger protein 7; Sensitive to apoptosis gene protein", "protein_names_refseq": "RING-box protein 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103161028)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0097602 cullin family protein binding;GO:0061663 NEDD8 ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0031466 Cul5-RING ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051895 negative regulation of focal adhesion assembly;GO:0070979 protein K11-linked ubiquitination;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MV87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MVD9-1", "uniprot_id": [ { "id": "A0A8C2MVD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MVD9", "type": "external" } ], "mass": 83444.0, "length": 743, "protein_name": "Aspartyl/asparaginyl beta-hydroxylase", "gene_name": "Asph", "organism": "Hamster", "refseq_name": "aspartyl/asparaginyl beta-hydroxylase isoform X6", "refseq_ac": [ { "id": "XP_027254684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254684", "type": "external" } ], "gene_names_uniprotkb": "Asph", "gene_names_refseq": "Asph", "protein_names_uniprotkb": "Aspartyl/asparaginyl beta-hydroxylase; 1.14.11.16; Aspartate beta-hydroxylase; Peptide-aspartate beta-dioxygenase", "protein_names_refseq": "aspartyl/asparaginyl beta-hydroxylase isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100755768)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.16", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.16", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0062101 peptidyl-aspartic acid 3-dioxygenase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032541 cortical endoplasmic reticulum;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0031647 regulation of protein stability;GO:0045862 positive regulation of proteolysis;GO:1901879 regulation of protein depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MVD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MVF9-1", "uniprot_id": [ { "id": "A0A8C2MVF9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MVF9", "type": "external" } ], "mass": 38047.0, "length": 341, "protein_name": "Retinol dehydrogenase 10", "gene_name": "Rdh10", "organism": "Hamster", "refseq_name": "retinol dehydrogenase 10 isoform X2", "refseq_ac": [ { "id": "XP_027254615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254615", "type": "external" } ], "gene_names_uniprotkb": "Rdh10", "gene_names_refseq": "Rdh10", "protein_names_uniprotkb": "Retinol dehydrogenase 10; 1.1.1.300", "protein_names_refseq": "retinol dehydrogenase 10 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765162)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" } ], "go_molecular_function": "GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity;GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042574 retinal metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MVF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MVQ0-1", "uniprot_id": [ { "id": "A0A8C2MVQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MVQ0", "type": "external" } ], "mass": 290683.0, "length": 2558, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp9x", "organism": "Hamster", "refseq_name": "probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1", "refseq_ac": [ { "id": "XP_027288944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288944", "type": "external" } ], "gene_names_uniprotkb": "Usp9x", "gene_names_refseq": "Usp9x", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763346)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity;GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005929 cilium;GO:0030426 growth cone", "go_biological_process": "GO:0070536 protein K63-linked deubiquitination;GO:0001764 neuron migration;GO:0006307 DNA alkylation repair;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MVQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MWL1-1", "uniprot_id": [ { "id": "A0A8C2MWL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MWL1", "type": "external" } ], "mass": 20625.0, "length": 183, "protein_name": "Ubiquitin-conjugating enzyme E2 H", "gene_name": "Ube2h", "organism": "Hamster", "refseq_name": "ubiquitin-conjugating enzyme E2 H isoform X2", "refseq_ac": [ { "id": "XP_027247195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247195", "type": "external" } ], "gene_names_uniprotkb": "Ube2h", "gene_names_refseq": "Ube2h", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 H; (E3-independent) E2 ubiquitin-conjugating enzyme H; 2.3.2.23; 2.3.2.24; E2 ubiquitin-conjugating enzyme H; Ubiquitin carrier protein H; Ubiquitin-conjugating enzyme E2-20K; Ubiquitin-protein ligase H", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 H isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763741)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "", "go_biological_process": "GO:0070979 protein K11-linked ubiquitination;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MWL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MVZ3-1", "uniprot_id": [ { "id": "A0A8C2MVZ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MVZ3", "type": "external" } ], "mass": 21008.0, "length": 187, "protein_name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 isoform X2", "gene_name": "Bnip3", "organism": "Hamster", "refseq_name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 isoform X1", "refseq_ac": [ { "id": "XP_007652080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652080", "type": "external" } ], "gene_names_uniprotkb": "Bnip3", "gene_names_refseq": "Bnip3", "protein_names_uniprotkb": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 isoform X2", "protein_names_refseq": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774634)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 149 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616047.1) and transcript sequence (JI869565.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0051020 GTPase binding;GO:0140506 endoplasmic reticulum-autophagosome adaptor activity;GO:0140580 mitochondrion autophagosome adaptor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005741 mitochondrial outer membrane;GO:0014069 postsynaptic density;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0051607 defense response to virus;GO:0071260 cellular response to mechanical stimulus;GO:0072593 reactive oxygen species metabolic process;GO:0090200 positive regulation of release of cytochrome c from mitochondria", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MVZ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N1Z2-1", "uniprot_id": [ { "id": "A0A8C2N1Z2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N1Z2", "type": "external" } ], "mass": 527512.0, "length": 4836, "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "Herc2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase HERC2 isoform X1", "refseq_ac": [ { "id": "XP_027260540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260540", "type": "external" } ], "gene_names_uniprotkb": "Herc2", "gene_names_refseq": "Herc2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HERC2; 2.3.2.26; HECT domain and RCC1-like domain-containing protein 2; HECT-type E3 ubiquitin transferase HERC2", "protein_names_refseq": "E3 ubiquitin-protein ligase HERC2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758957)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes. Recruited to sites of DNA damage in response to ionizing radiation (IR) and facilitates the assembly of UBE2N and RNF8 promoting DNA damage-induced formation of 'Lys-63'-linked ubiquitin chains. Acts as a mediator of binding specificity between UBE2N and RNF8. Involved in the maintenance of RNF168 levels. E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of XPA which influences the circadian oscillation of DNA excision repair activity. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Also modulates iron metabolism by regulating the basal turnover of FBXL5., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031625 ubiquitin protein ligase binding;GO:0032183 SUMO binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005814 centriole;GO:0005829 cytosol", "go_biological_process": "GO:0006281 DNA repair;GO:0016567 protein ubiquitination;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N1Z2-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MX50-1", "uniprot_id": [ { "id": "A0A8C2MX50_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MX50", "type": "external" } ], "mass": 274021.0, "length": 2491, "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "Igf2r", "organism": "Hamster", "refseq_name": "cation-independent mannose-6-phosphate receptor isoform X2", "refseq_ac": [ { "id": "XP_027256896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256896", "type": "external" } ], "gene_names_uniprotkb": "Igf2r", "gene_names_refseq": "Igf2r", "protein_names_uniprotkb": "Cation-independent mannose-6-phosphate receptor; 300 kDa mannose 6-phosphate receptor; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; M6P/IGF2 receptor", "protein_names_refseq": "cation-independent mannose-6-phosphate receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762916)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation by binding DPP4., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051219 phosphoprotein binding;GO:0005520 insulin-like growth factor binding;GO:0005537 D-mannose binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005641 nuclear envelope lumen;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0044794 host-mediated activation of viral process;GO:0007041 lysosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MX50-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MXB1-1", "uniprot_id": [ { "id": "A0A8C2MXB1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MXB1", "type": "external" } ], "mass": 50562.0, "length": 461, "protein_name": "Interleukin-6 receptor subunit alpha isoform X3", "gene_name": "Il6r", "organism": "Hamster", "refseq_name": "interleukin-6 receptor subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_007640506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640506", "type": "external" } ], "gene_names_uniprotkb": "Il6r", "gene_names_refseq": "Il6r", "protein_names_uniprotkb": "Interleukin-6 receptor subunit alpha isoform X3", "protein_names_refseq": "interleukin-6 receptor subunit alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750971)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 101 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613854.1) and transcript sequence (IACG01061298.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007640506.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004897 ciliary neurotrophic factor receptor activity;GO:0004915 interleukin-6 receptor activity;GO:0019981 interleukin-6 binding;GO:0070119 ciliary neurotrophic factor binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0070110 ciliary neurotrophic factor receptor complex;GO:0005896 interleukin-6 receptor complex;GO:0005576 extracellular region;GO:0009897 external side of plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0072126 positive regulation of glomerular mesangial cell proliferation;GO:0032722 positive regulation of chemokine production;GO:0032755 positive regulation of interleukin-6 production;GO:0048661 positive regulation of smooth muscle cell proliferation;GO:0010573 vascular endothelial growth factor production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MXB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MXN0-1", "uniprot_id": [ { "id": "A0A8C2MXN0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MXN0", "type": "external" } ], "mass": 21770.0, "length": 194, "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "Rnf4", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF4 isoform X1", "refseq_ac": [ { "id": "XP_003508897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508897", "type": "external" } ], "gene_names_uniprotkb": "Rnf4", "gene_names_refseq": "Rnf4", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF4; 2.3.2.27; RING finger protein 4", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770179)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation. Regulates the degradation of several proteins including PML and the transcriptional activator PEA3. Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation. Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1. Alternatively, it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor-mediated transcriptional activation. Catalyzes ubiquitination of sumoylated PARP1 in response to PARP1 trapping to chromatin, leading to PARP1 removal from chromatin by VCP/p97., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0032184 SUMO polymer binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0046685 response to arsenic-containing substance;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0090169 regulation of spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MXN0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MXN2-1", "uniprot_id": [ { "id": "A0A8C2MXN2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MXN2", "type": "external" } ], "mass": 51981.0, "length": 452, "protein_name": "Glycine receptor subunit alpha-2 isoform X2", "gene_name": "Glra2", "organism": "Hamster", "refseq_name": "glycine receptor subunit alpha-2 isoform X2", "refseq_ac": [ { "id": "XP_003503294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503294", "type": "external" } ], "gene_names_uniprotkb": "Glra2", "gene_names_refseq": "Glra2", "protein_names_uniprotkb": "Glycine receptor subunit alpha-2 isoform X2", "protein_names_refseq": "glycine receptor subunit alpha-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751068)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613952.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0016934 extracellularly glycine-gated chloride channel activity;GO:0022852 glycine-gated chloride ion channel activity;GO:0004888 transmembrane signaling receptor activity;GO:0016594 glycine binding;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0034707 chloride channel complex;GO:0042995 cell projection;GO:0098690 glycinergic synapse;GO:0099634 postsynaptic specialization membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0071361 cellular response to ethanol;GO:0050804 modulation of chemical synaptic transmission;GO:0071230 cellular response to amino acid stimulus;GO:0071294 cellular response to zinc ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MXN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MXZ2-1", "uniprot_id": [ { "id": "A0A8C2MXZ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MXZ2", "type": "external" } ], "mass": 392350.0, "length": 3430, "protein_name": "Utrophin", "gene_name": "Utrn", "organism": "Hamster", "refseq_name": "utrophin isoform X1", "refseq_ac": [ { "id": "XP_007638873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638873", "type": "external" } ], "gene_names_uniprotkb": "Utrn", "gene_names_refseq": "Utrn", "protein_names_uniprotkb": "Utrophin; Dystrophin-related protein 1", "protein_names_refseq": "utrophin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757299)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613761.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in anchoring the cytoskeleton to the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005178 integrin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0017166 vinculin binding", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0031594 neuromuscular junction;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0001954 positive regulation of cell-matrix adhesion;GO:0090257 regulation of muscle system process;GO:0099536 synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MXZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MY72-1", "uniprot_id": [ { "id": "A0A8C2MY72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MY72", "type": "external" } ], "mass": 79208.0, "length": 729, "protein_name": "Denticleless protein homolog", "gene_name": "Dtl", "organism": "Hamster", "refseq_name": "denticleless protein homolog isoform X2", "refseq_ac": [ { "id": "XP_027272324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272324", "type": "external" } ], "gene_names_uniprotkb": "Dtl", "gene_names_refseq": "Dtl", "protein_names_uniprotkb": "Denticleless protein homolog; Lethal(2) denticleless protein homolog; Retinoic acid-regulated nuclear matrix-associated protein", "protein_names_refseq": "denticleless protein homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750427)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0031965 nuclear membrane;GO:0005694 chromosome", "go_biological_process": "GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009411 response to UV;GO:0048511 rhythmic process;GO:0045732 positive regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MY72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MYD2-1", "uniprot_id": [ { "id": "A0A8C2MYD2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MYD2", "type": "external" } ], "mass": 50431.0, "length": 487, "protein_name": "mRNA decay activator protein ZFP36", "gene_name": "LOC113835924", "organism": "Hamster", "refseq_name": "mRNA decay activator protein ZFP36L2", "refseq_ac": [ { "id": "XP_027273732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273732", "type": "external" } ], "gene_names_uniprotkb": "LOC113835924", "gene_names_refseq": "LOC113835924", "protein_names_uniprotkb": "mRNA decay activator protein ZFP36; Zinc finger protein 36", "protein_names_refseq": "mRNA decay activator protein ZFP36L2", "tax_id": 10029, "disease": "", "pathway": " (cge:113835924)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0045577 regulation of B cell differentiation;GO:0009611 response to wounding;GO:0070371 ERK1 and ERK2 cascade;GO:0071560 cellular response to transforming growth factor beta stimulus;GO:0006402 mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MYD2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MYH8-1", "uniprot_id": [ { "id": "A0A8C2MYH8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MYH8", "type": "external" } ], "mass": 74229.0, "length": 706, "protein_name": "Synapsin-1", "gene_name": "Syn1", "organism": "Hamster", "refseq_name": "synapsin-1 isoform X3", "refseq_ac": [ { "id": "XP_027288076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288076", "type": "external" } ], "gene_names_uniprotkb": "Syn1", "gene_names_refseq": "Syn1", "protein_names_uniprotkb": "Synapsin-1; Synapsin I", "protein_names_refseq": "synapsin-1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100766138)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton;GO:0014069 postsynaptic density;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0099504 synaptic vesicle cycle;GO:0007269 neurotransmitter secretion;GO:2000300 regulation of synaptic vesicle exocytosis;GO:0098693 regulation of synaptic vesicle cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MYH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MYZ7-1", "uniprot_id": [ { "id": "A0A8C2MYZ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MYZ7", "type": "external" } ], "mass": 48310.0, "length": 433, "protein_name": "Urokinase-type plasminogen activator", "gene_name": "Plau", "organism": "Hamster", "refseq_name": "urokinase-type plasminogen activator", "refseq_ac": [ { "id": "XP_003496775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496775", "type": "external" } ], "gene_names_uniprotkb": "Plau", "gene_names_refseq": "Plau", "protein_names_uniprotkb": "Urokinase-type plasminogen activator; 3.4.21.73", "protein_names_refseq": "urokinase-type plasminogen activator", "tax_id": 10029, "disease": "", "pathway": " (cge:100759384)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613632.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0033628 regulation of cell adhesion mediated by integrin;GO:2000097 regulation of smooth muscle cell-matrix adhesion;GO:0014910 regulation of smooth muscle cell migration;GO:0042730 fibrinolysis;GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MYZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N6L4-1", "uniprot_id": [ { "id": "A0A8C2N6L4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N6L4", "type": "external" } ], "mass": 77790.0, "length": 686, "protein_name": "cGMP-dependent protein kinase", "gene_name": "Prkg1", "organism": "Hamster", "refseq_name": "cGMP-dependent protein kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_003500272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500272", "type": "external" } ], "gene_names_uniprotkb": "Prkg1", "gene_names_refseq": "Prkg1", "protein_names_uniprotkb": "cGMP-dependent protein kinase; 2.7.11.12", "protein_names_refseq": "cGMP-dependent protein kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768615)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613782.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004692 cGMP-dependent protein kinase activity;GO:0005524 ATP binding;GO:0030553 cGMP binding;GO:0005246 calcium channel regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0060087 relaxation of vascular associated smooth muscle;GO:0043114 regulation of vascular permeability;GO:0048668 collateral sprouting;GO:0007168 receptor guanylyl cyclase signaling pathway;GO:0090331 negative regulation of platelet aggregation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N6L4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MZ94-1", "uniprot_id": [ { "id": "A0A8C2MZ94_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MZ94", "type": "external" } ], "mass": 67047.0, "length": 589, "protein_name": "Guanylate-binding protein 2 isoform X3", "gene_name": "LOC100765968", "organism": "Hamster", "refseq_name": "guanylate-binding protein 2 isoform X1", "refseq_ac": [ { "id": "XP_003515496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515496", "type": "external" } ], "gene_names_uniprotkb": "LOC100765968", "gene_names_refseq": "LOC100765968", "protein_names_uniprotkb": "Guanylate-binding protein 2 isoform X3", "protein_names_refseq": "guanylate-binding protein 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765968)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1566 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003618062.1) and transcript sequence (IACG01095885.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003515496.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042803 protein homodimerization activity;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0051607 defense response to virus;GO:0006605 protein targeting;GO:0034504 protein localization to nucleus;GO:0042742 defense response to bacterium;GO:0071346 cellular response to type II interferon", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MZ94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MZC0-1", "uniprot_id": [ { "id": "A0A8C2MZC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MZC0", "type": "external" } ], "mass": 41208.0, "length": 361, "protein_name": "Popeye domain-containing protein 1", "gene_name": "Bves", "organism": "Hamster", "refseq_name": "blood vessel epicardial substance", "refseq_ac": [ { "id": "XP_003509717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509717", "type": "external" } ], "gene_names_uniprotkb": "Bves", "gene_names_refseq": "Bves", "protein_names_uniprotkb": "Popeye domain-containing protein 1; Blood vessel epicardial substance", "protein_names_refseq": "blood vessel epicardial substance", "tax_id": 10029, "disease": "", "pathway": " (cge:100770468)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614750.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0030552 cAMP binding", "go_cellular_component": "GO:0005923 bicellular tight junction;GO:0005901 caveola;GO:0042383 sarcolemma;GO:0016328 lateral plasma membrane;GO:0031253 cell projection membrane", "go_biological_process": "GO:0002931 response to ischemia;GO:0042391 regulation of membrane potential;GO:0034446 substrate adhesion-dependent cell spreading;GO:0008360 regulation of cell shape;GO:0001921 positive regulation of receptor recycling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MZC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MZE3-1", "uniprot_id": [ { "id": "A0A8C2MZE3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MZE3", "type": "external" } ], "mass": 146609.0, "length": 1286, "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "Smc4", "organism": "Hamster", "refseq_name": "structural maintenance of chromosomes protein 4 isoform X1", "refseq_ac": [ { "id": "XP_003512101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512101", "type": "external" } ], "gene_names_uniprotkb": "Smc4", "gene_names_refseq": "Smc4", "protein_names_uniprotkb": "Structural maintenance of chromosomes protein", "protein_names_refseq": "structural maintenance of chromosomes protein 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766744)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 225 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615335.1) and transcript sequence (IACG01053479.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003512101.1. COMPLETENESS: full length., [RefSeq]; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0000775 chromosome, centromeric region;GO:0000796 condensin complex", "go_biological_process": "GO:1905820 positive regulation of chromosome separation;GO:0051984 positive regulation of chromosome segregation;GO:0051301 cell division;GO:0021987 cerebral cortex development;GO:0007076 mitotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MZE3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2MZF4-1", "uniprot_id": [ { "id": "A0A8C2MZF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2MZF4", "type": "external" } ], "mass": 30968.0, "length": 282, "protein_name": "NAD(P)H-hydrate epimerase", "gene_name": "Naxe", "organism": "Hamster", "refseq_name": "NAD(P)H-hydrate epimerase isoform X2", "refseq_ac": [ { "id": "XP_027248885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248885", "type": "external" } ], "gene_names_uniprotkb": "Naxe; AIBP; APOA1BP", "gene_names_refseq": "Naxe", "protein_names_uniprotkb": "NAD(P)H-hydrate epimerase; 5.1.99.6; AI-BP; Apolipoprotein A-I-binding protein; NAD(P)HX epimerase", "protein_names_refseq": "NAD(P)H-hydrate epimerase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762326)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.1.99.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.6", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0052856 NAD(P)HX epimerase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005929 cilium;GO:0044297 cell body", "go_biological_process": "GO:0016525 negative regulation of angiogenesis;GO:0002040 sprouting angiogenesis;GO:0010874 regulation of cholesterol efflux;GO:0046496 nicotinamide nucleotide metabolic process;GO:0031580 membrane raft distribution", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2MZF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N055-1", "uniprot_id": [ { "id": "A0A8C2N055_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N055", "type": "external" } ], "mass": 160299.0, "length": 1433, "protein_name": "3'-5' RNA helicase YTHDC2", "gene_name": "Ythdc2", "organism": "Hamster", "refseq_name": "3'-5' RNA helicase YTHDC2 isoform X4", "refseq_ac": [ { "id": "XP_027256650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256650", "type": "external" } ], "gene_names_uniprotkb": "Ythdc2", "gene_names_refseq": "Ythdc2", "protein_names_uniprotkb": "3'-5' RNA helicase YTHDC2; 3.6.4.13", "protein_names_refseq": "3'-5' RNA helicase YTHDC2 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100772467)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease. Required for both spermatogenesis and oogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0070063 RNA polymerase binding;GO:0034458 3'-5' RNA helicase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm;GO:0035770 ribonucleoprotein granule", "go_biological_process": "GO:0044829 host-mediated activation of viral genome replication;GO:0034612 response to tumor necrosis factor;GO:0007286 spermatid development;GO:0070555 response to interleukin-1;GO:0048599 oocyte development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N055-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N090-1", "uniprot_id": [ { "id": "A0A8C2N090_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N090", "type": "external" } ], "mass": 53427.0, "length": 476, "protein_name": "Carboxypeptidase E", "gene_name": "Cpe", "organism": "Hamster", "refseq_name": "carboxypeptidase E isoform X2", "refseq_ac": [ { "id": "XP_027249865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249865", "type": "external" } ], "gene_names_uniprotkb": "Cpe", "gene_names_refseq": "Cpe", "protein_names_uniprotkb": "Carboxypeptidase E; 3.4.17.10; Carboxypeptidase H; Enkephalin convertase; Prohormone-processing carboxypeptidase", "protein_names_refseq": "carboxypeptidase E isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757401)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sorting receptor that directs prohormones to the regulated secretory pathway. Also acts as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0050839 cell adhesion molecule binding;GO:0004181 metallocarboxypeptidase activity;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005794 Golgi apparatus;GO:0030658 transport vesicle membrane;GO:0030667 secretory granule membrane", "go_biological_process": "GO:0006518 peptide metabolic process;GO:0016055 Wnt signaling pathway;GO:0072657 protein localization to membrane;GO:0030072 peptide hormone secretion;GO:0003214 cardiac left ventricle morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N090-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N0A2-1", "uniprot_id": [ { "id": "A0A8C2N0A2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N0A2", "type": "external" } ], "mass": 60607.0, "length": 531, "protein_name": "Parafibromin", "gene_name": "Cdc73", "organism": "Hamster", "refseq_name": "parafibromin isoform X1", "refseq_ac": [ { "id": "XP_007645808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645808", "type": "external" } ], "gene_names_uniprotkb": "Cdc73", "gene_names_refseq": "Cdc73", "protein_names_uniprotkb": "Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein homolog", "protein_names_refseq": "parafibromin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767294)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 214 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614323.1) and transcript sequence (IACG01043997.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007645808.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000993 RNA polymerase II complex binding", "go_cellular_component": "GO:0016593 Cdc73/Paf1 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0050680 negative regulation of epithelial cell proliferation;GO:0071222 cellular response to lipopolysaccharide;GO:0048147 negative regulation of fibroblast proliferation;GO:0019827 stem cell population maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N0A2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N0M0-1", "uniprot_id": [ { "id": "A0A8C2N0M0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N0M0", "type": "external" } ], "mass": 32244.0, "length": 294, "protein_name": "Endonuclease", "gene_name": "Endog", "organism": "Hamster", "refseq_name": "endonuclease G, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027278956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278956", "type": "external" } ], "gene_names_uniprotkb": "Endog", "gene_names_refseq": "Endog", "protein_names_uniprotkb": "Endonuclease; 3.1.30.-", "protein_names_refseq": "endonuclease G, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770499)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endonuclease that preferentially catalyzes the cleavage of double-stranded 5-hydroxymethylcytosine (5hmC)-modified DNA. The 5hmC-modified nucleotide does not increase the binding affinity, but instead increases the efficiency of cutting and specifies the site of cleavage for the modified DNAs. Shows significantly higher affinity for four-stranded Holliday junction over duplex and single-stranded DNAs. Promotes conservative recombination when the DNA is 5hmC-modified. Promotes autophagy through the suppression of mTOR by its phosphorylation-mediated interaction with YWHAG and its endonuclease activity-mediated DNA damage response. GSK3-beta mediated phosphorylation of ENDOG enhances its interaction with YWHAG, leading to the release of TSC2 and PIK3C3 from YWHAG resulting in mTOR pathway suppression and autophagy initiation. Promotes cleavage of mtDNA in response to oxidative and nitrosative stress, in turn inducing compensatory mtDNA replication., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0003676 nucleic acid binding;GO:0004521 RNA endonuclease activity;GO:0000014 single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0090297 positive regulation of mitochondrial DNA replication;GO:0006974 DNA damage response;GO:0010508 positive regulation of autophagy;GO:0032007 negative regulation of TOR signaling;GO:0006309 apoptotic DNA fragmentation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N0M0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N0T1-1", "uniprot_id": [ { "id": "A0A8C2N0T1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N0T1", "type": "external" } ], "mass": 60085.0, "length": 516, "protein_name": "Delta(24)-sterol reductase", "gene_name": "Dhcr24", "organism": "Hamster", "refseq_name": "delta(24)-sterol reductase isoform X1", "refseq_ac": [ { "id": "XP_007642000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642000", "type": "external" } ], "gene_names_uniprotkb": "Dhcr24", "gene_names_refseq": "Dhcr24", "protein_names_uniprotkb": "Delta(24)-sterol reductase; 1.3.1.72; 24-dehydrocholesterol reductase; 3-beta-hydroxysterol Delta-24-reductase", "protein_names_refseq": "delta(24)-sterol reductase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769920)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 159 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613599.1) and transcript sequence (IACG01094652.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007642000.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.72", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.72", "type": "external" } ], "go_molecular_function": "GO:0019899 enzyme binding;GO:0071949 FAD binding;GO:0042605 peptide antigen binding;GO:0000246 Delta24(24-1) sterol reductase activity;GO:0050614 Delta24-sterol reductase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043588 skin development;GO:0009888 tissue development;GO:0033489 cholesterol biosynthetic process via desmosterol;GO:0033490 cholesterol biosynthetic process via lathosterol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N0T1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N0Z5-1", "uniprot_id": [ { "id": "A0A8C2N0Z5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N0Z5", "type": "external" } ], "mass": 80065.0, "length": 721, "protein_name": "Bardet-Biedl syndrome 2 protein homolog", "gene_name": "Bbs2", "organism": "Hamster", "refseq_name": "Bardet-Biedl syndrome 2 protein", "refseq_ac": [ { "id": "XP_027261415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261415", "type": "external" } ], "gene_names_uniprotkb": "Bbs2", "gene_names_refseq": "Bbs2", "protein_names_uniprotkb": "Bardet-Biedl syndrome 2 protein homolog", "protein_names_refseq": "Bardet-Biedl syndrome 2 protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100756643)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0031514 motile cilium;GO:0034451 centriolar satellite;GO:0036064 ciliary basal body;GO:0005902 microvillus;GO:0060170 ciliary membrane", "go_biological_process": "GO:0007601 visual perception;GO:0045444 fat cell differentiation;GO:1905515 non-motile cilium assembly;GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway;GO:0060296 regulation of cilium beat frequency involved in ciliary motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N0Z5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N179-1", "uniprot_id": [ { "id": "A0A8C2N179_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N179", "type": "external" } ], "mass": 84136.0, "length": 734, "protein_name": "Ubiquitin thioesterase ZRANB1", "gene_name": "Zranb1", "organism": "Hamster", "refseq_name": "ubiquitin thioesterase ZRANB1 isoform X1", "refseq_ac": [ { "id": "XP_003507329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507329", "type": "external" } ], "gene_names_uniprotkb": "Zranb1", "gene_names_refseq": "Zranb1", "protein_names_uniprotkb": "Ubiquitin thioesterase ZRANB1; 3.4.19.12; Zinc finger Ran-binding domain-containing protein 1", "protein_names_refseq": "ubiquitin thioesterase ZRANB1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769882)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614349.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003507329.1. COMPLETENESS: full length., [RefSeq]; Ubiquitin thioesterase, which specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Acts as a regulator of autophagy by mediating deubiquitination of PIK3C3/VPS34, thereby promoting autophagosome maturation. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016477 cell migration;GO:0070536 protein K63-linked deubiquitination;GO:0007010 cytoskeleton organization;GO:0016055 Wnt signaling pathway;GO:0030177 positive regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N179-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N185-1", "uniprot_id": [ { "id": "A0A8C2N185_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N185", "type": "external" } ], "mass": 73193.0, "length": 648, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mak", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase MAK isoform X1", "refseq_ac": [ { "id": "XP_003506565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506565", "type": "external" } ], "gene_names_uniprotkb": "Mak", "gene_names_refseq": "Mak", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase MAK isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762243)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614251.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0031514 motile cilium;GO:0001917 photoreceptor inner segment", "go_biological_process": "GO:0045494 photoreceptor cell maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N185-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N1G2-1", "uniprot_id": [ { "id": "A0A8C2N1G2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N1G2", "type": "external" } ], "mass": 80392.0, "length": 727, "protein_name": "Ski oncogene", "gene_name": "Ski", "organism": "Hamster", "refseq_name": "ski oncogene isoform X2", "refseq_ac": [ { "id": "XP_027254310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254310", "type": "external" } ], "gene_names_uniprotkb": "Ski", "gene_names_refseq": "Ski", "protein_names_uniprotkb": "Ski oncogene; Proto-oncogene c-Ski", "protein_names_refseq": "ski oncogene isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755403)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005667 transcription regulator complex;GO:0016605 PML body;GO:0005634 nucleus", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0030514 negative regulation of BMP signaling pathway;GO:0032926 negative regulation of activin receptor signaling pathway;GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045668 negative regulation of osteoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N1G2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N1Q7-1", "uniprot_id": [ { "id": "A0A8C2N1Q7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N1Q7", "type": "external" } ], "mass": 105438.0, "length": 950, "protein_name": "Netrin receptor UNC5", "gene_name": "Unc5c", "organism": "Hamster", "refseq_name": "netrin receptor UNC5C isoform X3", "refseq_ac": [ { "id": "XP_035307532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307532", "type": "external" } ], "gene_names_uniprotkb": "Unc5c", "gene_names_refseq": "Unc5c", "protein_names_uniprotkb": "Netrin receptor UNC5", "protein_names_refseq": "netrin receptor UNC5C isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762557)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0015631 tubulin binding;GO:0005043 netrin receptor activity involved in chemorepulsion;GO:0005042 netrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0030425 dendrite;GO:0030426 growth cone;GO:0043025 neuronal cell body", "go_biological_process": "GO:0006915 apoptotic process;GO:0061643 chemorepulsion of axon;GO:1990791 dorsal root ganglion development;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N1Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N1S3-1", "uniprot_id": [ { "id": "A0A8C2N1S3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N1S3", "type": "external" } ], "mass": 42958.0, "length": 375, "protein_name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "gene_name": "Pisd", "organism": "Hamster", "refseq_name": "phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X3", "refseq_ac": [ { "id": "XP_003504169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504169", "type": "external" } ], "gene_names_uniprotkb": "Pisd; PISD", "gene_names_refseq": "Pisd", "protein_names_uniprotkb": "Phosphatidylserine decarboxylase proenzyme, mitochondrial; 4.1.1.65", "protein_names_refseq": "phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X3", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614033.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.65", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.65", "type": "external" } ], "go_molecular_function": "GO:0004609 phosphatidylserine decarboxylase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005811 lipid droplet", "go_biological_process": "GO:0016540 protein autoprocessing;GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N1S3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N281-1", "uniprot_id": [ { "id": "A0A8C2N281_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N281", "type": "external" } ], "mass": 100834.0, "length": 882, "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "gene_name": "Ndst1", "organism": "Hamster", "refseq_name": "bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X3", "refseq_ac": [ { "id": "XP_027258626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258626", "type": "external" } ], "gene_names_uniprotkb": "Ndst1", "gene_names_refseq": "Ndst1", "protein_names_uniprotkb": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; 2.8.2.8; Glucosaminyl N-deacetylase/N-sulfotransferase 1", "protein_names_refseq": "bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100766710)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.8.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.-", "type": "external" }, { "id": "2.8.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.8", "type": "external" } ], "go_molecular_function": "GO:0015016 heparan sulfate N-sulfotransferase activity;GO:0050119 N-acetylglucosamine deacetylase activity;GO:0102140 heparan sulfate N-deacetylase activity;GO:0016787 hydrolase activity;GO:0019213 deacetylase activity", "go_cellular_component": "GO:0032588 trans-Golgi network membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0030210 heparin proteoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N281-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N2A1-1", "uniprot_id": [ { "id": "A0A8C2N2A1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N2A1", "type": "external" } ], "mass": 19414.0, "length": 169, "protein_name": "N-alpha-acetyltransferase 50", "gene_name": "Naa50", "organism": "Hamster", "refseq_name": "N-alpha-acetyltransferase 50 isoform X3", "refseq_ac": [ { "id": "XP_035300434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300434", "type": "external" } ], "gene_names_uniprotkb": "Naa50", "gene_names_refseq": "Naa50", "protein_names_uniprotkb": "N-alpha-acetyltransferase 50; 2.3.1.258; N-epsilon-acetyltransferase 50; NatE catalytic subunit", "protein_names_refseq": "N-alpha-acetyltransferase 50 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773295)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.258", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.258", "type": "external" }, { "id": "2.3.1.256", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.256", "type": "external" } ], "go_molecular_function": "GO:0010485 histone H4 acetyltransferase activity;GO:0120518 protein N-terminal-methionine acetyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0031415 NatA complex;GO:0005634 nucleus", "go_biological_process": "GO:0043687 post-translational protein modification;GO:0071962 mitotic sister chromatid cohesion, centromeric;GO:0034087 establishment of mitotic sister chromatid cohesion;GO:0007064 mitotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N2A1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N2L0-1", "uniprot_id": [ { "id": "A0A8C2N2L0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N2L0", "type": "external" } ], "mass": 51772.0, "length": 458, "protein_name": "Kynurenine--oxoglutarate transaminase 1", "gene_name": "Kyat1", "organism": "Hamster", "refseq_name": "kynurenine--oxoglutarate transaminase 1 isoform X1", "refseq_ac": [ { "id": "XP_027278966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278966", "type": "external" } ], "gene_names_uniprotkb": "Kyat1", "gene_names_refseq": "Kyat1", "protein_names_uniprotkb": "Kynurenine--oxoglutarate transaminase 1; 2.6.1.64; 2.6.1.7; 4.4.1.13; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; Glutamine--phenylpyruvate transaminase; Kynurenine aminotransferase 1; Kynurenine aminotransferase I", "protein_names_refseq": "kynurenine--oxoglutarate transaminase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769821)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.64", "type": "external" }, { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.63", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.63", "type": "external" }, { "id": "2.6.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.39", "type": "external" }, { "id": "2.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.4", "type": "external" }, { "id": "2.6.1.73", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.73", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0047316 glutamine-phenylpyruvate transaminase activity;GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0042803 protein homodimerization activity;GO:0047804 cysteine-S-conjugate beta-lyase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0070189 kynurenine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N2L0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N2N6-1", "uniprot_id": [ { "id": "A0A8C2N2N6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N2N6", "type": "external" } ], "mass": 39363.0, "length": 369, "protein_name": "ADP-ribosylhydrolase ARH3", "gene_name": "Adprs", "organism": "Hamster", "refseq_name": "ADP-ribose glycohydrolase ARH3 isoform X2", "refseq_ac": [ { "id": "XP_027255083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255083", "type": "external" } ], "gene_names_uniprotkb": "Adprs", "gene_names_refseq": "Adprs", "protein_names_uniprotkb": "ADP-ribosylhydrolase ARH3; 3.2.1.143; ADP-ribose glycohydrolase ARH3; ADP-ribosylhydrolase 3; O-acetyl-ADP-ribose deacetylase ARH3; Poly(ADP-ribose) glycohydrolase ARH3; [Protein ADP-ribosylarginine] hydrolase-like protein 2; [Protein ADP-ribosylserine] hydrolase", "protein_names_refseq": "ADP-ribose glycohydrolase ARH3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762798)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.143", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.143", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004649 poly(ADP-ribose) glycohydrolase activity;GO:0061463 O-acetyl-ADP-ribose deacetylase activity;GO:0140292 ADP-ribosylserine hydrolase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005759 mitochondrial matrix;GO:0090734 site of DNA damage", "go_biological_process": "GO:0006281 DNA repair;GO:0060546 negative regulation of necroptotic process;GO:0071451 cellular response to superoxide;GO:0140290 peptidyl-serine ADP-deribosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N2N6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N2V4-1", "uniprot_id": [ { "id": "A0A8C2N2V4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N2V4", "type": "external" } ], "mass": 61105.0, "length": 541, "protein_name": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase", "gene_name": "LOC100772408", "organism": "Hamster", "refseq_name": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase isoform X3", "refseq_ac": [ { "id": "XP_035306251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306251", "type": "external" } ], "gene_names_uniprotkb": "LOC100772408", "gene_names_refseq": "LOC100772408", "protein_names_uniprotkb": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase; 2.4.1.47; Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase", "protein_names_refseq": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100772408)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.47", "type": "external" } ], "go_molecular_function": "GO:0003851 N-acylsphingosine galactosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0048812 neuron projection morphogenesis;GO:0007010 cytoskeleton organization;GO:0030913 paranodal junction assembly;GO:0006682 galactosylceramide biosynthetic process;GO:0002175 protein localization to paranode region of axon", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N2V4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N350-1", "uniprot_id": [ { "id": "A0A8C2N350_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N350", "type": "external" } ], "mass": 332368.0, "length": 2880, "protein_name": "Desmoplakin", "gene_name": "Dsp", "organism": "Hamster", "refseq_name": "desmoplakin isoform X2", "refseq_ac": [ { "id": "XP_027266183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266183", "type": "external" } ], "gene_names_uniprotkb": "Dsp", "gene_names_refseq": "Dsp", "protein_names_uniprotkb": "Desmoplakin", "protein_names_refseq": "desmoplakin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767947)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005080 protein kinase C binding;GO:0005198 structural molecule activity;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0016323 basolateral plasma membrane;GO:0005882 intermediate filament;GO:0014704 intercalated disc", "go_biological_process": "GO:0150105 protein localization to cell-cell junction;GO:0086091 regulation of heart rate by cardiac conduction;GO:0030216 keratinocyte differentiation;GO:0045109 intermediate filament organization;GO:0042060 wound healing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N350-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N3C9-1", "uniprot_id": [ { "id": "A0A8C2N3C9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N3C9", "type": "external" } ], "mass": 85951.0, "length": 761, "protein_name": "Ribosomal protein S6 kinase", "gene_name": "LOC100773612", "organism": "Hamster", "refseq_name": "ribosomal protein S6 kinase alpha-2 isoform X2", "refseq_ac": [ { "id": "XP_027256941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256941", "type": "external" } ], "gene_names_uniprotkb": "LOC100773612", "gene_names_refseq": "LOC100773612", "protein_names_uniprotkb": "Ribosomal protein S6 kinase; 2.7.11.1", "protein_names_refseq": "ribosomal protein S6 kinase alpha-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773612)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004711 ribosomal protein S6 kinase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0072687 meiotic spindle", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0045786 negative regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N3C9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N3H2-1", "uniprot_id": [ { "id": "A0A8C2N3H2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N3H2", "type": "external" } ], "mass": 110724.0, "length": 1004, "protein_name": "Ephrin type-A receptor 8", "gene_name": "Epha8", "organism": "Hamster", "refseq_name": "ephrin type-A receptor 8 isoform X2", "refseq_ac": [ { "id": "XP_035294785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294785", "type": "external" } ], "gene_names_uniprotkb": "Epha8", "gene_names_refseq": "Epha8", "protein_names_uniprotkb": "Ephrin type-A receptor 8; 2.7.10.1; EPH- and ELK-related kinase; Tyrosine-protein kinase receptor EEK", "protein_names_refseq": "ephrin type-A receptor 8 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769287)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system also plays a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0005005 transmembrane-ephrin receptor activity;GO:0005004 GPI-linked ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0031901 early endosome membrane", "go_biological_process": "GO:0033628 regulation of cell adhesion mediated by integrin;GO:0007155 cell adhesion;GO:0016322 neuron remodeling;GO:0043410 positive regulation of MAPK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N3H2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N3Z4-1", "uniprot_id": [ { "id": "A0A8C2N3Z4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N3Z4", "type": "external" } ], "mass": 48105.0, "length": 420, "protein_name": "Dynein axonemal assembly factor 4", "gene_name": "Dnaaf4", "organism": "Hamster", "refseq_name": "dynein assembly factor 4, axonemal isoform X1", "refseq_ac": [ { "id": "XP_035300369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300369", "type": "external" } ], "gene_names_uniprotkb": "Dnaaf4", "gene_names_refseq": "Dnaaf4", "protein_names_uniprotkb": "Dynein axonemal assembly factor 4; Dyslexia susceptibility 1 candidate gene 1 protein homolog", "protein_names_refseq": "dynein assembly factor 4, axonemal isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769043)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005829 cytosol;GO:0043005 neuron projection;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0003351 epithelial cilium movement involved in extracellular fluid movement;GO:0007399 nervous system development;GO:0007507 heart development;GO:0007368 determination of left/right symmetry;GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N3Z4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N466-1", "uniprot_id": [ { "id": "A0A8C2N466_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N466", "type": "external" } ], "mass": 88801.0, "length": 788, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgkg", "organism": "Hamster", "refseq_name": "diacylglycerol kinase gamma isoform X1", "refseq_ac": [ { "id": "XP_035300577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300577", "type": "external" } ], "gene_names_uniprotkb": "Dgkg", "gene_names_refseq": "Dgkg", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase gamma isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757224)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has no apparent specificity with regard to the acyl compositions of diacylglycerol. Specifically expressed in the cerebellum where it controls the level of diacylglycerol which in turn regulates the activity of protein kinase C gamma. Through protein kinase C gamma, indirectly regulates the dendritic development of Purkinje cells, cerebellar long term depression and ultimately cerebellar motor coordination., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0050773 regulation of dendrite development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N466-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N4D4-1", "uniprot_id": [ { "id": "A0A8C2N4D4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N4D4", "type": "external" } ], "mass": 50386.0, "length": 466, "protein_name": "Zinc finger protein ZIC 3", "gene_name": "LOC113837794", "organism": "Hamster", "refseq_name": "zinc finger protein ZIC 3", "refseq_ac": [ { "id": "XP_027289242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289242", "type": "external" } ], "gene_names_uniprotkb": "LOC113837794", "gene_names_refseq": "LOC113837794", "protein_names_uniprotkb": "Zinc finger protein ZIC 3", "protein_names_refseq": "zinc finger protein ZIC 3", "tax_id": 10029, "disease": "", "pathway": " (cge:113837794)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0048863 stem cell differentiation;GO:0021766 hippocampus development;GO:0030324 lung development;GO:0001501 skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N4D4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N4P6-1", "uniprot_id": [ { "id": "A0A8C2N4P6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N4P6", "type": "external" } ], "mass": 92243.0, "length": 855, "protein_name": "E3 ubiquitin-protein ligase TRIM71", "gene_name": "Trim71", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase TRIM71 isoform X2", "refseq_ac": [ { "id": "XP_027271345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271345", "type": "external" } ], "gene_names_uniprotkb": "Trim71", "gene_names_refseq": "Trim71", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM71; 2.3.2.27; Protein lin-41 homolog; RING-type E3 ubiquitin transferase TRIM71; Tripartite motif-containing protein 71", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM71 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767742)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0030371 translation repressor activity;GO:0035198 miRNA binding", "go_cellular_component": "GO:0000932 P-body", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0021915 neural tube development;GO:0000082 G1/S transition of mitotic cell cycle;GO:0000209 protein polyubiquitination;GO:0035196 miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N4P6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N5H4-1", "uniprot_id": [ { "id": "A0A8C2N5H4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N5H4", "type": "external" } ], "mass": 67774.0, "length": 577, "protein_name": "Moesin", "gene_name": "Msn", "organism": "Hamster", "refseq_name": "moesin", "refseq_ac": [ { "id": "XP_003508298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508298", "type": "external" } ], "gene_names_uniprotkb": "Msn", "gene_names_refseq": "Msn", "protein_names_uniprotkb": "Moesin", "protein_names_refseq": "moesin", "tax_id": 10029, "disease": "", "pathway": " (cge:100751956)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 164 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614508.1) and transcript sequence (JI886260.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003508298.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding;GO:0050839 cell adhesion molecule binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:1902966 positive regulation of protein localization to early endosome;GO:0022614 membrane to membrane docking;GO:0061028 establishment of endothelial barrier;GO:1902115 regulation of organelle assembly;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N5H4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N5R1-1", "uniprot_id": [ { "id": "A0A8C2N5R1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N5R1", "type": "external" } ], "mass": 18358.0, "length": 165, "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "Pin1", "organism": "Hamster", "refseq_name": "peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 isoform X1", "refseq_ac": [ { "id": "XP_007638696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638696", "type": "external" } ], "gene_names_uniprotkb": "Pin1", "gene_names_refseq": "Pin1", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase; 5.2.1.8", "protein_names_refseq": "peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773691)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 190 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613752.1) and transcript sequence (IACG01005387.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0031434 mitogen-activated protein kinase kinase binding;GO:0050815 phosphoserine residue binding;GO:0008013 beta-catenin binding;GO:0032794 GTPase activating protein binding;GO:0050816 phosphothreonine residue binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0016607 nuclear speck;GO:0030496 midbody;GO:0036064 ciliary basal body;GO:0099524 postsynaptic cytosol", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:1902430 negative regulation of amyloid-beta formation;GO:0071456 cellular response to hypoxia;GO:0007266 Rho protein signal transduction;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N5R1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N5W4-1", "uniprot_id": [ { "id": "A0A8C2N5W4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N5W4", "type": "external" } ], "mass": 97340.0, "length": 860, "protein_name": "Protein argonaute-3", "gene_name": "LOC100769090", "organism": "Hamster", "refseq_name": "protein argonaute-3 isoform X1", "refseq_ac": [ { "id": "XP_003500941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500941", "type": "external" } ], "gene_names_uniprotkb": "LOC100769090; AGO3; EIF2C3", "gene_names_refseq": "LOC100769090", "protein_names_uniprotkb": "Protein argonaute-3; Argonaute3; Eukaryotic translation initiation factor 2C 3; eIF-2C 3; eIF2C 3", "protein_names_refseq": "protein argonaute-3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769090)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613817.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding;GO:0035198 miRNA binding;GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0000932 P-body;GO:0016442 RISC complex;GO:0070578 RISC-loading complex", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0010628 positive regulation of gene expression;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0006402 mRNA catabolic process;GO:0031054 pre-miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N5W4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N6C9-1", "uniprot_id": [ { "id": "A0A8C2N6C9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N6C9", "type": "external" } ], "mass": 93303.0, "length": 841, "protein_name": "Axin-2", "gene_name": "Axin2", "organism": "Hamster", "refseq_name": "axin-2", "refseq_ac": [ { "id": "XP_003500365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500365", "type": "external" } ], "gene_names_uniprotkb": "Axin2", "gene_names_refseq": "Axin2", "protein_names_uniprotkb": "Axin-2", "protein_names_refseq": "axin-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750382)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613786.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019901 protein kinase binding;GO:0031625 ubiquitin protein ligase binding;GO:0008013 beta-catenin binding;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030877 beta-catenin destruction complex", "go_biological_process": "GO:0048255 mRNA stabilization;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:1903053 regulation of extracellular matrix organization;GO:0008104 intracellular protein localization;GO:0042476 odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N6C9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N6J6-1", "uniprot_id": [ { "id": "A0A8C2N6J6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N6J6", "type": "external" } ], "mass": 46579.0, "length": 412, "protein_name": "Argininosuccinate synthase", "gene_name": "Ass1", "organism": "Hamster", "refseq_name": "argininosuccinate synthase isoform X3", "refseq_ac": [ { "id": "XP_035303017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303017", "type": "external" } ], "gene_names_uniprotkb": "Ass1", "gene_names_refseq": "Ass1", "protein_names_uniprotkb": "Argininosuccinate synthase; 6.3.4.5; Citrulline--aspartate ligase", "protein_names_refseq": "argininosuccinate synthase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762274)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016597 amino acid binding;GO:0004055 argininosuccinate synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:0006531 aspartate metabolic process;GO:0007623 circadian rhythm;GO:0000050 urea cycle;GO:0000052 citrulline metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N6J6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N6T3-1", "uniprot_id": [ { "id": "A0A8C2N6T3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N6T3", "type": "external" } ], "mass": 145861.0, "length": 1262, "protein_name": "Unconventional myosin-VI", "gene_name": "Myo6", "organism": "Hamster", "refseq_name": "unconventional myosin-VI isoform X1", "refseq_ac": [ { "id": "XP_027296903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027296903", "type": "external" } ], "gene_names_uniprotkb": "Myo6", "gene_names_refseq": "Myo6", "protein_names_uniprotkb": "Unconventional myosin-VI; Unconventional myosin-6", "protein_names_refseq": "unconventional myosin-VI isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765167)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614605.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005905 clathrin-coated pit;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0042491 inner ear auditory receptor cell differentiation;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0015031 protein transport;GO:0042472 inner ear morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N6T3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F8I2-1", "uniprot_id": [ { "id": "A0A9J7F8I2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F8I2", "type": "external" } ], "mass": 85312.0, "length": 774, "protein_name": "Glucocorticoid receptor", "gene_name": "Nr3c1", "organism": "Hamster", "refseq_name": "glucocorticoid receptor isoform X2", "refseq_ac": [ { "id": "XP_027253807", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253807", "type": "external" } ], "gene_names_uniprotkb": "Nr3c1", "gene_names_refseq": "Nr3c1", "protein_names_uniprotkb": "Glucocorticoid receptor; Nuclear receptor subfamily 3 group C member 1", "protein_names_refseq": "glucocorticoid receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763961)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has transcriptional activation and repression activity. Mediates glucocorticoid-induced apoptosis. Promotes accurate chromosome segregation during mitosis. May act as a tumor suppressor. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004883 nuclear glucocorticoid receptor activity;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0005819 spindle;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0048708 astrocyte differentiation;GO:0097305 response to alcohol;GO:0006351 DNA-templated transcription;GO:0010906 regulation of glucose metabolic process;GO:0035249 synaptic transmission, glutamatergic", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F8I2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2NBS1-1", "uniprot_id": [ { "id": "A0A8C2NBS1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2NBS1", "type": "external" } ], "mass": 76276.0, "length": 677, "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2", "gene_name": "Alox15b", "organism": "Hamster", "refseq_name": "polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2", "refseq_ac": [ { "id": "XP_027281990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281990", "type": "external" } ], "gene_names_uniprotkb": "Alox15b", "gene_names_refseq": "Alox15b", "protein_names_uniprotkb": "Polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2", "protein_names_refseq": "polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754473)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005509 calcium ion binding;GO:0016165 linoleate 13S-lipoxygenase activity;GO:0036403 arachidonate 8(S)-lipoxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0034440 lipid oxidation;GO:0019369 arachidonate metabolic process;GO:0071926 endocannabinoid signaling pathway;GO:0008285 negative regulation of cell population proliferation;GO:0032722 positive regulation of chemokine production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2NBS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N7G4-1", "uniprot_id": [ { "id": "A0A8C2N7G4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N7G4", "type": "external" } ], "mass": 56638.0, "length": 518, "protein_name": "Retinal dehydrogenase 2 isoform X3", "gene_name": "Aldh1a2", "organism": "Hamster", "refseq_name": "retinal dehydrogenase 2 isoform X3", "refseq_ac": [ { "id": "XP_035300347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300347", "type": "external" } ], "gene_names_uniprotkb": "Aldh1a2", "gene_names_refseq": "Aldh1a2", "protein_names_uniprotkb": "Retinal dehydrogenase 2 isoform X3", "protein_names_refseq": "retinal dehydrogenase 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100772304)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001758 retinal dehydrogenase (NAD+) activity;GO:0004028 3-chloroallyl aldehyde dehydrogenase activity;GO:0004029 aldehyde dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0051289 protein homotetramerization;GO:0071300 cellular response to retinoic acid;GO:0002138 retinoic acid biosynthetic process;GO:0021915 neural tube development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N7G4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N9D3-1", "uniprot_id": [ { "id": "A0A8C2N9D3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N9D3", "type": "external" } ], "mass": 27362.0, "length": 261, "protein_name": "Aquaporin-8", "gene_name": "Aqp8", "organism": "Hamster", "refseq_name": "aquaporin-8", "refseq_ac": [ { "id": "XP_003514369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514369", "type": "external" } ], "gene_names_uniprotkb": "Aqp8", "gene_names_refseq": "Aqp8", "protein_names_uniprotkb": "Aquaporin-8", "protein_names_refseq": "aquaporin-8", "tax_id": 10029, "disease": "", "pathway": " (cge:100762692)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616515.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003514369.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity;GO:0015265 urea channel activity;GO:0008519 ammonium channel activity;GO:0015264 methylammonium channel activity", "go_cellular_component": "GO:0097708 intracellular vesicle;GO:0005743 mitochondrial inner membrane;GO:0016323 basolateral plasma membrane;GO:0030868 smooth endoplasmic reticulum membrane;GO:0046691 intracellular canaliculus", "go_biological_process": "GO:0071320 cellular response to cAMP;GO:0045540 regulation of cholesterol biosynthetic process;GO:0030183 B cell differentiation;GO:1990748 cellular detoxification;GO:0080170 hydrogen peroxide transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N9D3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2N9X1-1", "uniprot_id": [ { "id": "A0A8C2N9X1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2N9X1", "type": "external" } ], "mass": 66678.0, "length": 601, "protein_name": "Dual specificity tyrosine-phosphorylation-regulated kinase 2", "gene_name": "Dyrk2", "organism": "Hamster", "refseq_name": "dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1", "refseq_ac": [ { "id": "XP_003497192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497192", "type": "external" } ], "gene_names_uniprotkb": "Dyrk2", "gene_names_refseq": "Dyrk2", "protein_names_uniprotkb": "Dual specificity tyrosine-phosphorylation-regulated kinase 2; 2.7.12.1", "protein_names_refseq": "dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771845)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 589 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613642.1) and transcript sequence (IACG01062959.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003497192.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0030145 manganese ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0000151 ubiquitin ligase complex;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0070885 negative regulation of calcineurin-NFAT signaling cascade;GO:0045725 positive regulation of glycogen biosynthetic process;GO:0007224 smoothened signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2N9X1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2NB25-1", "uniprot_id": [ { "id": "A0A8C2NB25_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2NB25", "type": "external" } ], "mass": 76988.0, "length": 697, "protein_name": "E3 ubiquitin-protein ligase MARCHF7", "gene_name": "Marchf7", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase MARCHF7 isoform X2", "refseq_ac": [ { "id": "XP_027276164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276164", "type": "external" } ], "gene_names_uniprotkb": "Marchf7", "gene_names_refseq": "Marchf7", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MARCHF7; 2.3.2.27; Membrane-associated RING finger protein 7; Membrane-associated RING-CH protein VII; RING-type E3 ubiquitin transferase MARCHF7", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCHF7 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in T-cell proliferation by regulating LIF secretion. May play a role in lysosome homeostasis. Promotes 'Lys-6', 'Lys-11' and 'Lys-63'-linked mixed polyubiquitination on ATG14 leading to the inhibition of autophagy by impairing the interaction between ATG14 and STX7. Participates in the dopamine-mediated negative regulation of the NLRP3 inflammasome by promoting its ubiquitination and subsequent degradation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0043130 ubiquitin binding;GO:0097371 MDM2/MDM4 family protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0008284 positive regulation of cell population proliferation;GO:0050821 protein stabilization;GO:0051865 protein autoubiquitination;GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2NB25-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QBI1-1", "uniprot_id": [ { "id": "A0A8C2QBI1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QBI1", "type": "external" } ], "mass": 29555.0, "length": 265, "protein_name": "Elongator complex protein 6", "gene_name": "Elp6", "organism": "Hamster", "refseq_name": "elongator complex protein 6 isoform X1", "refseq_ac": [ { "id": "XP_003504296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504296", "type": "external" } ], "gene_names_uniprotkb": "Elp6", "gene_names_refseq": "Elp6", "protein_names_uniprotkb": "Elongator complex protein 6; Protein TMEM103", "protein_names_refseq": "elongator complex protein 6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764169)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 121 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614047.1) and transcript sequence (IACG01057627.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Involved in cell migration., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0033588 elongator holoenzyme complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QBI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QBJ1-1", "uniprot_id": [ { "id": "A0A8C2QBJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QBJ1", "type": "external" } ], "mass": 39578.0, "length": 349, "protein_name": "Dysbindin isoform X3", "gene_name": "Dtnbp1", "organism": "Hamster", "refseq_name": "dysbindin isoform X1", "refseq_ac": [ { "id": "XP_007644114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644114", "type": "external" } ], "gene_names_uniprotkb": "Dtnbp1", "gene_names_refseq": "Dtnbp1", "protein_names_uniprotkb": "Dysbindin isoform X3", "protein_names_refseq": "dysbindin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760065)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 180 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613609.1) and transcript sequence (IACG01091945.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007644114.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0014069 postsynaptic density;GO:0030426 growth cone;GO:0043197 dendritic spine", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0014059 regulation of dopamine secretion;GO:0048812 neuron projection morphogenesis;GO:0030036 actin cytoskeleton organization;GO:0060155 platelet dense granule organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QBJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QC31-1", "uniprot_id": [ { "id": "A0A8C2QC31_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QC31", "type": "external" } ], "mass": 63588.0, "length": 557, "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "Il1rl1", "organism": "Hamster", "refseq_name": "interleukin-1 receptor-like 1 isoform X1", "refseq_ac": [ { "id": "XP_007638752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638752", "type": "external" } ], "gene_names_uniprotkb": "Il1rl1", "gene_names_refseq": "Il1rl1", "protein_names_uniprotkb": "Interleukin-1 receptor-like 1", "protein_names_refseq": "interleukin-1 receptor-like 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760768)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613754.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibits IL-33 signaling., [UniProtKB, UniProtKB]; Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002113 interleukin-33 binding;GO:0002114 interleukin-33 receptor activity;GO:0016787 hydrolase activity;GO:0004908 interleukin-1 receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009897 external side of plasma membrane;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0032754 positive regulation of interleukin-5 production;GO:0043032 positive regulation of macrophage activation;GO:0006954 inflammatory response;GO:0032689 negative regulation of type II interferon production;GO:0032722 positive regulation of chemokine production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QC31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QC64-1", "uniprot_id": [ { "id": "A0A8C2QC64_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QC64", "type": "external" } ], "mass": 345046.0, "length": 3094, "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "Ranbp2", "organism": "Hamster", "refseq_name": "E3 SUMO-protein ligase RanBP2 isoform X2", "refseq_ac": [ { "id": "XP_027244142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244142", "type": "external" } ], "gene_names_uniprotkb": "Ranbp2", "gene_names_refseq": "Ranbp2", "protein_names_uniprotkb": "E3 SUMO-protein ligase RanBP2; Ran-binding protein 2", "protein_names_refseq": "E3 SUMO-protein ligase RanBP2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762334)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019209 kinase activator activity;GO:0061665 SUMO ligase activity;GO:0003723 RNA binding;GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0044614 nuclear pore cytoplasmic filaments", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0016925 protein sumoylation;GO:0006457 protein folding;GO:0051168 nuclear export;GO:0051642 centrosome localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QC64-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QC69-1", "uniprot_id": [ { "id": "A0A8C2QC69_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QC69", "type": "external" } ], "mass": 52588.0, "length": 475, "protein_name": "D(1B) dopamine receptor", "gene_name": "Drd5", "organism": "Hamster", "refseq_name": "D(1B) dopamine receptor isoform X2", "refseq_ac": [ { "id": "XP_027242499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242499", "type": "external" } ], "gene_names_uniprotkb": "Drd5", "gene_names_refseq": "Drd5", "protein_names_uniprotkb": "D(1B) dopamine receptor; D(5) dopamine receptor; Dopamine D5 receptor", "protein_names_refseq": "D(1B) dopamine receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752680)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0035240 dopamine binding;GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs", "go_cellular_component": "GO:0045202 synapse;GO:0031526 brush border membrane;GO:0060170 ciliary membrane;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0008306 associative learning;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0008217 regulation of blood pressure;GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QC69-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCH2-1", "uniprot_id": [ { "id": "A0A8C2QCH2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCH2", "type": "external" } ], "mass": 78255.0, "length": 699, "protein_name": "PGAP2-interacting protein", "gene_name": "Cwh43", "organism": "Hamster", "refseq_name": "PGAP2-interacting protein isoform X3", "refseq_ac": [ { "id": "XP_035309128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309128", "type": "external" } ], "gene_names_uniprotkb": "Cwh43", "gene_names_refseq": "Cwh43", "protein_names_uniprotkb": "PGAP2-interacting protein; Cell wall biogenesis protein 43 C-terminal homolog", "protein_names_refseq": "PGAP2-interacting protein isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100764522)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in lipid remodeling during GPI-anchor maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCP6-1", "uniprot_id": [ { "id": "A0A8C2QCP6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCP6", "type": "external" } ], "mass": 33249.0, "length": 295, "protein_name": "Biliverdin reductase A", "gene_name": "Blvra", "organism": "Hamster", "refseq_name": "biliverdin reductase A", "refseq_ac": [ { "id": "XP_003497860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497860", "type": "external" } ], "gene_names_uniprotkb": "Blvra", "gene_names_refseq": "Blvra", "protein_names_uniprotkb": "Biliverdin reductase A; 1.3.1.24; BVR A", "protein_names_refseq": "biliverdin reductase A", "tax_id": 10029, "disease": "", "pathway": " (cge:100751522)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613665.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Does not reduce bilirubin IXbeta. Uses the reactants NADH or NADPH depending on the pH; NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7). NADPH, however, is the probable reactant in biological systems., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.24", "type": "external" } ], "go_molecular_function": "GO:0106276 biliberdin reductase (NADH) activity;GO:0004674 protein serine/threonine kinase activity;GO:0008270 zinc ion binding;GO:0000166 nucleotide binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0009986 cell surface", "go_biological_process": "GO:0042167 heme catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCQ0-1", "uniprot_id": [ { "id": "A0A8C2QCQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCQ0", "type": "external" } ], "mass": 33053.0, "length": 288, "protein_name": "Syntaxin-1A", "gene_name": "Stx1a", "organism": "Hamster", "refseq_name": "syntaxin-1A isoform X1", "refseq_ac": [ { "id": "XP_007639844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639844", "type": "external" } ], "gene_names_uniprotkb": "Stx1a", "gene_names_refseq": "Stx1a", "protein_names_uniprotkb": "Syntaxin-1A", "protein_names_refseq": "syntaxin-1A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759989)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 108 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613822.1) and transcript sequence (IACG01087082.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm. Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019869 chloride channel inhibitor activity;GO:0042802 identical protein binding;GO:0019900 kinase binding;GO:0000149 SNARE binding;GO:0019855 calcium channel inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0031965 nuclear membrane;GO:0030672 synaptic vesicle membrane;GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016925 protein sumoylation;GO:2000463 positive regulation of excitatory postsynaptic potential;GO:0030073 insulin secretion;GO:0010807 regulation of synaptic vesicle priming", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCQ7-1", "uniprot_id": [ { "id": "A0A8C2QCQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCQ7", "type": "external" } ], "mass": 70559.0, "length": 639, "protein_name": "SUMO-activating enzyme subunit 2", "gene_name": "Uba2", "organism": "Hamster", "refseq_name": "SUMO-activating enzyme subunit 2 isoform X2", "refseq_ac": [ { "id": "XP_027286056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286056", "type": "external" } ], "gene_names_uniprotkb": "Uba2", "gene_names_refseq": "Uba2", "protein_names_uniprotkb": "SUMO-activating enzyme subunit 2; 2.3.2.-", "protein_names_refseq": "SUMO-activating enzyme subunit 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764381)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 249 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) and transcript sequence (IACG01095711.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027286056.1. COMPLETENESS: full length., [RefSeq]; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019948 SUMO activating enzyme activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0046982 protein heterodimerization activity;GO:0016740 transferase activity", "go_cellular_component": "GO:0031510 SUMO activating enzyme complex;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0016925 protein sumoylation;GO:0033235 positive regulation of protein sumoylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCS1-1", "uniprot_id": [ { "id": "A0A8C2QCS1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCS1", "type": "external" } ], "mass": 102536.0, "length": 917, "protein_name": "Hexokinase-2", "gene_name": "Hk2", "organism": "Hamster", "refseq_name": "hexokinase-2", "refseq_ac": [ { "id": "XP_027285241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285241", "type": "external" } ], "gene_names_uniprotkb": "Hk2", "gene_names_refseq": "Hk2", "protein_names_uniprotkb": "Hexokinase-2; 2.7.1.1; Hexokinase type II", "protein_names_refseq": "hexokinase-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772205)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" } ], "go_molecular_function": "GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0005524 ATP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol", "go_biological_process": "GO:0035795 negative regulation of mitochondrial membrane permeability;GO:0045766 positive regulation of angiogenesis;GO:2000378 negative regulation of reactive oxygen species metabolic process;GO:0001678 intracellular glucose homeostasis;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCS1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QCZ2-1", "uniprot_id": [ { "id": "A0A8C2QCZ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QCZ2", "type": "external" } ], "mass": 97040.0, "length": 861, "protein_name": "Protein argonaute-4", "gene_name": "LOC100762217", "organism": "Hamster", "refseq_name": "protein argonaute-4 isoform X2", "refseq_ac": [ { "id": "XP_027255088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255088", "type": "external" } ], "gene_names_uniprotkb": "LOC100762217; AGO4; EIF2C4", "gene_names_refseq": "LOC100762217", "protein_names_uniprotkb": "Protein argonaute-4; Argonaute4; Eukaryotic translation initiation factor 2C 4; eIF-2C 4; eIF2C 4", "protein_names_refseq": "protein argonaute-4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762217)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding;GO:0035198 miRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0016442 RISC complex;GO:0070578 RISC-loading complex", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0006402 mRNA catabolic process;GO:0031054 pre-miRNA processing;GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0006417 regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QCZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QD06-1", "uniprot_id": [ { "id": "A0A8C2QD06_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QD06", "type": "external" } ], "mass": 59673.0, "length": 536, "protein_name": "Atrial natriuretic peptide receptor 3", "gene_name": "Npr3", "organism": "Hamster", "refseq_name": "atrial natriuretic peptide receptor 3 isoform X2", "refseq_ac": [ { "id": "XP_027257063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257063", "type": "external" } ], "gene_names_uniprotkb": "Npr3", "gene_names_refseq": "Npr3", "protein_names_uniprotkb": "Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor type C", "protein_names_refseq": "atrial natriuretic peptide receptor 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774587)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0031404 chloride ion binding;GO:0017046 peptide hormone binding;GO:0016941 natriuretic peptide receptor activity;GO:0042277 peptide binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0002931 response to ischemia;GO:0007165 signal transduction;GO:0001974 blood vessel remodeling;GO:0008217 regulation of blood pressure", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QD06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QDM2-1", "uniprot_id": [ { "id": "A0A8C2QDM2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QDM2", "type": "external" } ], "mass": 54095.0, "length": 469, "protein_name": "Cytosolic beta-glucosidase", "gene_name": "LOC100757820", "organism": "Hamster", "refseq_name": "cytosolic beta-glucosidase", "refseq_ac": [ { "id": "XP_007650423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650423", "type": "external" } ], "gene_names_uniprotkb": "LOC100757820", "gene_names_refseq": "LOC100757820", "protein_names_uniprotkb": "Cytosolic beta-glucosidase; 3.2.1.21; 3.2.1.45; 3.2.1.46; Cytosolic galactosylceramidase; Cytosolic glucosylceramidase; Cytosolic glycosylceramidase", "protein_names_refseq": "cytosolic beta-glucosidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100757820)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615206.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.45", "type": "external" }, { "id": "3.2.1.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.46", "type": "external" }, { "id": "3.2.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.21", "type": "external" } ], "go_molecular_function": "GO:0004348 glucosylceramidase activity;GO:0008422 beta-glucosidase activity;GO:0004565 beta-galactosidase activity;GO:0004336 galactosylceramidase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0016052 carbohydrate catabolic process;GO:0046477 glycosylceramide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QDM2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QE27-1", "uniprot_id": [ { "id": "A0A8C2QE27_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QE27", "type": "external" } ], "mass": 26771.0, "length": 233, "protein_name": "TIR domain-containing adapter molecule 2", "gene_name": "Ticam2", "organism": "Hamster", "refseq_name": "TIR domain-containing adapter molecule 2", "refseq_ac": [ { "id": "XP_035296043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296043", "type": "external" } ], "gene_names_uniprotkb": "Ticam2", "gene_names_refseq": "Ticam2", "protein_names_uniprotkb": "TIR domain-containing adapter molecule 2; TRIF-related adapter molecule; Toll/interleukin-1 receptor domain-containing protein", "protein_names_refseq": "TIR domain-containing adapter molecule 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758290)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a sorting adapter in different signaling pathways to facilitate downstream signaling leading to type I interferon induction. In TLR4 signaling, physically bridges TLR4 and TICAM1 and functionally transmits signal to TICAM1 in early endosomes after endocytosis of TLR4. In TLR2 signaling, physically bridges TLR2 and MYD88 and is required for the TLR2-dependent movement of MYD88 to endosomes following ligand engagement. Involved in IL-18 signaling and is proposed to function as a sorting adapter for MYD88 in IL-18 signaling during adaptive immune response. Forms a complex with RAB11FIP2 that is recruited to the phagosomes to promote the activation of the actin-regulatory GTPases RAC1 and CDC42 and subsequent phagocytosis of Gram-negative bacteria., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005770 late endosome", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0006909 phagocytosis;GO:0032755 positive regulation of interleukin-6 production;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QE27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QE29-1", "uniprot_id": [ { "id": "A0A8C2QE29_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QE29", "type": "external" } ], "mass": 46313.0, "length": 406, "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "gene_name": "Pip4k2a", "organism": "Hamster", "refseq_name": "phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2", "refseq_ac": [ { "id": "XP_027261114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261114", "type": "external" } ], "gene_names_uniprotkb": "Pip4k2a", "gene_names_refseq": "Pip4k2a", "protein_names_uniprotkb": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; 2.7.1.149; Diphosphoinositide kinase 2-alpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PtdIns(5)P-4-kinase isoform 2-alpha", "protein_names_refseq": "phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755254)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.149", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.149", "type": "external" } ], "go_molecular_function": "GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005776 autophagosome", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0035855 megakaryocyte development;GO:2000786 positive regulation of autophagosome assembly;GO:0090119 vesicle-mediated cholesterol transport;GO:0061909 autophagosome-lysosome fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QE29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFS7-1", "uniprot_id": [ { "id": "A0A9J7FFS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFS7", "type": "external" } ], "mass": 67210.0, "length": 606, "protein_name": "Mitogen-activated protein kinase kinase kinase 7", "gene_name": "Map3k7", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase kinase kinase 7 isoform X2", "refseq_ac": [ { "id": "XP_027259234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259234", "type": "external" } ], "gene_names_uniprotkb": "Map3k7", "gene_names_refseq": "Map3k7", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 7; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774341)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0030971 receptor tyrosine kinase binding;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0140672 ATAC complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QER3-1", "uniprot_id": [ { "id": "A0A8C2QER3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QER3", "type": "external" } ], "mass": 55433.0, "length": 492, "protein_name": "Beclin 1-associated autophagy-related key regulator isoform X2", "gene_name": "Atg14", "organism": "Hamster", "refseq_name": "beclin 1-associated autophagy-related key regulator isoform X2", "refseq_ac": [ { "id": "XP_027242354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242354", "type": "external" } ], "gene_names_uniprotkb": "Atg14", "gene_names_refseq": "Atg14", "protein_names_uniprotkb": "Beclin 1-associated autophagy-related key regulator isoform X2", "protein_names_refseq": "beclin 1-associated autophagy-related key regulator isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753411)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051020 GTPase binding;GO:0043495 protein-membrane adaptor activity;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity", "go_cellular_component": "GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site;GO:0045335 phagocytic vesicle;GO:0005776 autophagosome;GO:0005930 axoneme;GO:0035032 phosphatidylinositol 3-kinase complex, class III", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0000045 autophagosome assembly;GO:0010608 post-transcriptional regulation of gene expression;GO:0016241 regulation of macroautophagy;GO:0045022 early endosome to late endosome transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QER3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QEZ5-1", "uniprot_id": [ { "id": "A0A8C2QEZ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QEZ5", "type": "external" } ], "mass": 44648.0, "length": 398, "protein_name": "Meiotic recombination protein SPO11", "gene_name": "Spo11", "organism": "Hamster", "refseq_name": "meiotic recombination protein SPO11 isoform X2", "refseq_ac": [ { "id": "XP_027279066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279066", "type": "external" } ], "gene_names_uniprotkb": "Spo11", "gene_names_refseq": "Spo11", "protein_names_uniprotkb": "Meiotic recombination protein SPO11; 5.6.2.2", "protein_names_refseq": "meiotic recombination protein SPO11 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762801)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000228 nuclear chromosome;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0007283 spermatogenesis;GO:0042138 meiotic DNA double-strand break formation;GO:0000706 meiotic DNA double-strand break processing;GO:0007131 reciprocal meiotic recombination;GO:0007292 female gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QEZ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFC3-1", "uniprot_id": [ { "id": "A0A8C2QFC3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFC3", "type": "external" } ], "mass": 33171.0, "length": 293, "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "Nus1", "organism": "Hamster", "refseq_name": "dehydrodolichyl diphosphate synthase complex subunit NUS1 isoform X2", "refseq_ac": [ { "id": "XP_027257900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257900", "type": "external" } ], "gene_names_uniprotkb": "Nus1", "gene_names_refseq": "Nus1", "protein_names_uniprotkb": "Dehydrodolichyl diphosphate synthase complex subunit NUS1; 2.5.1.87; Dehydrodolichyl diphosphate synthase complex subunit nus1; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog", "protein_names_refseq": "dehydrodolichyl diphosphate synthase complex subunit NUS1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761477)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length. Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" }, { "id": "2.5.1.87", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.87", "type": "external" } ], "go_molecular_function": "GO:0045547 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:1904423 dehydrodolichyl diphosphate synthase complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0032383 regulation of intracellular cholesterol transport;GO:0038084 vascular endothelial growth factor signaling pathway;GO:0043048 dolichyl monophosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFV5-1", "uniprot_id": [ { "id": "A0A8C2QFV5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFV5", "type": "external" } ], "mass": 84325.0, "length": 735, "protein_name": "Two pore channel protein 2", "gene_name": "Tpcn2", "organism": "Hamster", "refseq_name": "two pore calcium channel protein 2 isoform X8", "refseq_ac": [ { "id": "XP_027264592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264592", "type": "external" } ], "gene_names_uniprotkb": "Tpcn2", "gene_names_refseq": "Tpcn2", "protein_names_uniprotkb": "Two pore channel protein 2; Two pore calcium channel protein 2", "protein_names_refseq": "two pore calcium channel protein 2 isoform X8", "tax_id": 10029, "disease": "", "pathway": " (cge:100755221)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; (Microbial infection) During Ebola virus (EBOV) infection, controls the movement of endosomes containing virus particles and is required by EBOV to escape from the endosomal network into the cell cytoplasm., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0072345 NAADP-sensitive calcium-release channel activity;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0015280 ligand-gated sodium channel activity", "go_cellular_component": "GO:0005829 cytosol;GO:0031902 late endosome membrane;GO:0036020 endolysosome membrane;GO:0034702 monoatomic ion channel complex;GO:0033162 melanosome membrane", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0010506 regulation of autophagy;GO:0006874 intracellular calcium ion homeostasis;GO:0007040 lysosome organization;GO:0051209 release of sequestered calcium ion into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFV5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QFZ4-1", "uniprot_id": [ { "id": "A0A8C2QFZ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QFZ4", "type": "external" } ], "mass": 569384.0, "length": 5194, "protein_name": "Usherin", "gene_name": "Ush2a", "organism": "Hamster", "refseq_name": "usherin", "refseq_ac": [ { "id": "XP_035300976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300976", "type": "external" } ], "gene_names_uniprotkb": "Ush2a", "gene_names_refseq": "Ush2a", "protein_names_uniprotkb": "Usherin; Usher syndrome type IIa protein homolog; Usher syndrome type-2A protein homolog", "protein_names_refseq": "usherin", "tax_id": 10029, "disease": "", "pathway": " (cge:107977174)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005518 collagen binding;GO:0017022 myosin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0001917 photoreceptor inner segment;GO:0005604 basement membrane;GO:0032391 photoreceptor connecting cilium", "go_biological_process": "GO:0048496 maintenance of animal organ identity;GO:0007601 visual perception;GO:0045494 photoreceptor cell maintenance;GO:0007605 sensory perception of sound;GO:0060113 inner ear receptor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QFZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG15-1", "uniprot_id": [ { "id": "A0A8C2QG15_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG15", "type": "external" } ], "mass": 27592.0, "length": 229, "protein_name": "C->U-editing enzyme APOBEC-1", "gene_name": "Apobec1", "organism": "Hamster", "refseq_name": "C->U-editing enzyme APOBEC-1", "refseq_ac": [ { "id": "XP_035304379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304379", "type": "external" } ], "gene_names_uniprotkb": "Apobec1", "gene_names_refseq": "Apobec1", "protein_names_uniprotkb": "C->U-editing enzyme APOBEC-1; 3.5.4.36; mRNA(cytosine(6666)) deaminase 1", "protein_names_refseq": "C->U-editing enzyme APOBEC-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760326)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.36", "type": "external" } ], "go_molecular_function": "GO:0004126 cytidine deaminase activity;GO:0008270 zinc ion binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030895 apolipoprotein B mRNA editing enzyme complex", "go_biological_process": "GO:0044029 positive regulation of gene expression via chromosomal CpG island demethylation;GO:0006397 mRNA processing;GO:0016554 cytidine to uridine editing;GO:0016556 mRNA modification;GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG15-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG30-1", "uniprot_id": [ { "id": "A0A8C2QG30_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG30", "type": "external" } ], "mass": 97235.0, "length": 865, "protein_name": "Interleukin-17 receptor A", "gene_name": "Il17ra", "organism": "Hamster", "refseq_name": "interleukin-17 receptor A isoform X1", "refseq_ac": [ { "id": "XP_027285110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285110", "type": "external" } ], "gene_names_uniprotkb": "Il17ra", "gene_names_refseq": "Il17ra", "protein_names_uniprotkb": "Interleukin-17 receptor A", "protein_names_refseq": "interleukin-17 receptor A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754214)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; (Microbial infection) Receptor for SARS coronavirus-2/SARS-CoV-2 virus protein ORF8, leading to IL17 pathway activation and an increased secretion of pro-inflammatory factors through activating NF-kappa-B signaling pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0030368 interleukin-17 receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0032747 positive regulation of interleukin-23 production;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0032755 positive regulation of interleukin-6 production;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG53-1", "uniprot_id": [ { "id": "A0A8C2QG53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG53", "type": "external" } ], "mass": 62287.0, "length": 578, "protein_name": "Solute carrier family 15 member 4", "gene_name": "Slc15a4", "organism": "Hamster", "refseq_name": "solute carrier family 15 member 4 isoform X2", "refseq_ac": [ { "id": "XP_027269657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269657", "type": "external" } ], "gene_names_uniprotkb": "Slc15a4", "gene_names_refseq": "Slc15a4", "protein_names_uniprotkb": "Solute carrier family 15 member 4; Peptide/histidine transporter 1", "protein_names_refseq": "solute carrier family 15 member 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005290 L-histidine transmembrane transporter activity;GO:0015333 peptide:proton symporter activity;GO:0071916 dipeptide transmembrane transporter activity;GO:0015647 peptidoglycan transmembrane transporter activity", "go_cellular_component": "GO:0031901 early endosome membrane;GO:0036020 endolysosome membrane", "go_biological_process": "GO:0048302 regulation of isotype switching to IgG isotypes;GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0015031 protein transport;GO:0045087 innate immune response;GO:0034157 positive regulation of toll-like receptor 7 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG86-1", "uniprot_id": [ { "id": "A0A8C2QG86_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG86", "type": "external" } ], "mass": 36825.0, "length": 326, "protein_name": "Interferon regulatory factor", "gene_name": "Irf1", "organism": "Hamster", "refseq_name": "interferon regulatory factor 1 isoform X2", "refseq_ac": [ { "id": "XP_027283326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283326", "type": "external" } ], "gene_names_uniprotkb": "Irf1", "gene_names_refseq": "Irf1", "protein_names_uniprotkb": "Interferon regulatory factor", "protein_names_refseq": "interferon regulatory factor 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756092)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation;GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0006351 DNA-templated transcription;GO:0051607 defense response to virus;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QG96-1", "uniprot_id": [ { "id": "A0A8C2QG96_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QG96", "type": "external" } ], "mass": 119879.0, "length": 1059, "protein_name": "Lysine-specific demethylase 4A", "gene_name": "Kdm4a", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 4A", "refseq_ac": [ { "id": "XP_003502741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502741", "type": "external" } ], "gene_names_uniprotkb": "Kdm4a", "gene_names_refseq": "Kdm4a", "protein_names_uniprotkb": "Lysine-specific demethylase 4A; 1.14.11.66; 1.14.11.69; JmjC domain-containing histone demethylation protein 3A; Jumonji domain-containing protein 2A; [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A", "protein_names_refseq": "lysine-specific demethylase 4A", "tax_id": 10029, "disease": "", "pathway": " (cge:100756054)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613906.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66", "type": "external" }, { "id": "1.14.11.69", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.69", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity;GO:0140681 histone H3K36me2/H3K36me3 demethylase activity;GO:0140005 histone H4K20me2 reader activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0045892 negative regulation of DNA-templated transcription;GO:0010507 negative regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QG96-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGC7-1", "uniprot_id": [ { "id": "A0A8C2QGC7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGC7", "type": "external" } ], "mass": 58970.0, "length": 539, "protein_name": "Alpha-aminoadipic semialdehyde dehydrogenase", "gene_name": "Aldh7a1", "organism": "Hamster", "refseq_name": "alpha-aminoadipic semialdehyde dehydrogenase isoform X1", "refseq_ac": [ { "id": "XP_007622016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007622016", "type": "external" } ], "gene_names_uniprotkb": "Aldh7a1", "gene_names_refseq": "Aldh7a1", "protein_names_uniprotkb": "Alpha-aminoadipic semialdehyde dehydrogenase; 1.2.1.31; 1.2.1.3; 1.2.1.8; Aldehyde dehydrogenase family 7 member A1; Antiquitin-1; Betaine aldehyde dehydrogenase; Delta1-piperideine-6-carboxylate dehydrogenase", "protein_names_refseq": "alpha-aminoadipic semialdehyde dehydrogenase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756509)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 234 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613682.1) and transcript sequence (JI895409.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.19", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.47", "type": "external" }, { "id": "1.2.1.46", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.46", "type": "external" }, { "id": "1.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.31", "type": "external" }, { "id": "1.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004043 L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity;GO:0008802 betaine-aldehyde dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGC7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QGD3-1", "uniprot_id": [ { "id": "A0A8C2QGD3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QGD3", "type": "external" } ], "mass": 22880.0, "length": 214, "protein_name": "Methyltransferase HEMK2", "gene_name": "N6amt1", "organism": "Hamster", "refseq_name": "methyltransferase N6AMT1", "refseq_ac": [ { "id": "XP_027268158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268158", "type": "external" } ], "gene_names_uniprotkb": "N6amt1", "gene_names_refseq": "N6amt1", "protein_names_uniprotkb": "Methyltransferase HEMK2; HemK methyltransferase family member 2; Lysine N-methyltransferase 9; Methylarsonite methyltransferase N6AMT1; Methyltransferase N6AMT1; Protein N(5)-glutamine methyltransferase", "protein_names_refseq": "methyltransferase N6AMT1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768580)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Methyltransferase that can methylate proteins and, to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. It however only plays a limited role in arsenic metabolism compared with AS3MT., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity;GO:0003676 nucleic acid binding;GO:0030791 arsenite methyltransferase activity;GO:1904047 S-adenosyl-L-methionine binding;GO:0036009 protein-glutamine N-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035657 eRF1 methyltransferase complex", "go_biological_process": "GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0009404 toxin metabolic process;GO:0045814 negative regulation of gene expression, epigenetic;GO:0018872 arsonoacetate metabolic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QGD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QH24-1", "uniprot_id": [ { "id": "A0A8C2QH24_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QH24", "type": "external" } ], "mass": 170325.0, "length": 1499, "protein_name": "Rho GTPase-activating protein 35", "gene_name": "Arhgap35", "organism": "Hamster", "refseq_name": "rho GTPase-activating protein 35 isoform X1", "refseq_ac": [ { "id": "XP_027286830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286830", "type": "external" } ], "gene_names_uniprotkb": "Arhgap35", "gene_names_refseq": "Arhgap35", "protein_names_uniprotkb": "Rho GTPase-activating protein 35; Glucocorticoid receptor DNA-binding factor 1", "protein_names_refseq": "rho GTPase-activating protein 35 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752481)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003924 GTPase activity;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0036064 ciliary basal body", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0008064 regulation of actin polymerization or depolymerization;GO:0006351 DNA-templated transcription;GO:0010976 positive regulation of neuron projection development;GO:0051056 regulation of small GTPase mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QH24-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHF9-1", "uniprot_id": [ { "id": "A0A8C2QHF9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHF9", "type": "external" } ], "mass": 225260.0, "length": 2011, "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 1", "gene_name": "Lrrk1", "organism": "Hamster", "refseq_name": "leucine-rich repeat serine/threonine-protein kinase 1", "refseq_ac": [ { "id": "XP_003499450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499450", "type": "external" } ], "gene_names_uniprotkb": "Lrrk1", "gene_names_refseq": "Lrrk1", "protein_names_uniprotkb": "Leucine-rich repeat serine/threonine-protein kinase 1; 2.7.11.1", "protein_names_refseq": "leucine-rich repeat serine/threonine-protein kinase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768506)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613734.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase which phosphorylates RAB proteins involved in intracellular trafficking. Phosphorylates RAB7A; this activity is dependent on protein kinase C (PKC) activation. Plays a role in the negative regulation of bone mass, acting through the maturation of osteoclasts., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHF9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHK6-1", "uniprot_id": [ { "id": "A0A8C2QHK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHK6", "type": "external" } ], "mass": 22102.0, "length": 205, "protein_name": "Basic helix-loop-helix transcription factor scleraxis", "gene_name": "Scx", "organism": "Hamster", "refseq_name": "basic helix-loop-helix transcription factor scleraxis", "refseq_ac": [ { "id": "XP_027260091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260091", "type": "external" } ], "gene_names_uniprotkb": "Scx", "gene_names_refseq": "Scx", "protein_names_uniprotkb": "Basic helix-loop-helix transcription factor scleraxis", "protein_names_refseq": "basic helix-loop-helix transcription factor scleraxis", "tax_id": 10029, "disease": "", "pathway": " (cge:100763601)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0070888 E-box binding;GO:0043425 bHLH transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0043066 negative regulation of apoptotic process;GO:0001894 tissue homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHL5-1", "uniprot_id": [ { "id": "A0A8C2QHL5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHL5", "type": "external" } ], "mass": 106039.0, "length": 957, "protein_name": "Calsyntenin-3", "gene_name": "Clstn3", "organism": "Hamster", "refseq_name": "calsyntenin-3", "refseq_ac": [ { "id": "XP_027284022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284022", "type": "external" } ], "gene_names_uniprotkb": "Clstn3", "gene_names_refseq": "Clstn3", "protein_names_uniprotkb": "Calsyntenin-3", "protein_names_refseq": "calsyntenin-3", "tax_id": 10029, "disease": "", "pathway": " (cge:100760360)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adipose-specific isoform that plays a key role in adaptive thermogenesis. Facilitates the efficient use of stored triglyceride by promoting multilocular morphology of thermogenic adipocytes: acts by inhibiting the activity of CIDEA and CIDEC on lipid droplets, thereby preventing lipid droplet fusion and facilitating lipid utilization. May also participate in adaptive thermogenesis by promoting sympathetic innervation of thermogenic adipose tissue: acts by driving secretion of neurotrophic factor S100B from brown adipocytes, stimulating neurite outgrowth from sympathetic neurons., [UniProtKB, UniProtKB]; Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with both neurexin-alpha and neurexin-beta proteins at the presynaptic membrane. Regulates the balance between excitatory and inhibitory synapses by inhibiting formation of excitatory parallel-fiber synapses and promoting formation of inhibitory synapses in the same neuron. May also be involved in ascorbate (vitamin C) uptake via its interaction with SLC23A2/SVCT2. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0098632 cell-cell adhesion mediator activity;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0000139 Golgi membrane;GO:0005811 lipid droplet;GO:0009986 cell surface", "go_biological_process": "GO:0051965 positive regulation of synapse assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050806 positive regulation of synaptic transmission;GO:1905606 regulation of presynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHL5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QHV1-1", "uniprot_id": [ { "id": "A0A8C2QHV1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QHV1", "type": "external" } ], "mass": 92167.0, "length": 826, "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "Ddx20", "organism": "Hamster", "refseq_name": "probable ATP-dependent RNA helicase DDX20 isoform X2", "refseq_ac": [ { "id": "XP_027249683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249683", "type": "external" } ], "gene_names_uniprotkb": "Ddx20", "gene_names_refseq": "Ddx20", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX20; 3.6.1.15; 3.6.4.13; Component of gems 3; DEAD box protein 20; DEAD box protein DP 103; Gemin-3", "protein_names_refseq": "probable ATP-dependent RNA helicase DDX20 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752364)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042826 histone deacetylase binding;GO:0017111 ribonucleoside triphosphate phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0032797 SMN complex;GO:0090571 RNA polymerase II transcription repressor complex;GO:0097504 Gemini of Cajal bodies", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0043065 positive regulation of apoptotic process;GO:0000387 spliceosomal snRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QHV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QI80-1", "uniprot_id": [ { "id": "A0A8C2QI80_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QI80", "type": "external" } ], "mass": 42881.0, "length": 379, "protein_name": "Mitogen-activated protein kinase", "gene_name": "Mapk3", "organism": "Hamster", "refseq_name": "mitogen-activated protein kinase 3 isoform X2", "refseq_ac": [ { "id": "XP_027260431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260431", "type": "external" } ], "gene_names_uniprotkb": "Mapk3", "gene_names_refseq": "Mapk3", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753149)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 105 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) and transcript sequence (IACG01088685.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027260431.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton", "go_biological_process": "GO:0072584 caveolin-mediated endocytosis;GO:2000641 regulation of early endosome to late endosome transport;GO:0009893 positive regulation of metabolic process;GO:0006915 apoptotic process;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QI80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIE5-1", "uniprot_id": [ { "id": "A0A8C2QIE5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIE5", "type": "external" } ], "mass": 34469.0, "length": 312, "protein_name": "Homeobox protein Hox-A11 isoform X2", "gene_name": "Hoxa11", "organism": "Hamster", "refseq_name": "homeobox protein Hox-A11 isoform X2", "refseq_ac": [ { "id": "XP_027285445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285445", "type": "external" } ], "gene_names_uniprotkb": "Hoxa11", "gene_names_refseq": "Hoxa11", "protein_names_uniprotkb": "Homeobox protein Hox-A11 isoform X2", "protein_names_refseq": "homeobox protein Hox-A11 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763010)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0001759 organ induction;GO:0007501 mesodermal cell fate specification;GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0009954 proximal/distal pattern formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIE5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QII0-1", "uniprot_id": [ { "id": "A0A8C2QII0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QII0", "type": "external" } ], "mass": 23419.0, "length": 213, "protein_name": "Heat shock protein beta-1", "gene_name": "Hspb1", "organism": "Hamster", "refseq_name": "heat shock protein beta-1 isoform X2", "refseq_ac": [ { "id": "XP_027271994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271994", "type": "external" } ], "gene_names_uniprotkb": "Hspb1", "gene_names_refseq": "Hspb1", "protein_names_uniprotkb": "Heat shock protein beta-1; Heat shock 27 kDa protein", "protein_names_refseq": "heat shock protein beta-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763481)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0051082 unfolded protein binding;GO:0005080 protein kinase C binding;GO:0008426 protein kinase C inhibitor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005829 cytosol;GO:0030018 Z disc;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0099641 anterograde axonal protein transport;GO:2001028 positive regulation of endothelial cell chemotaxis;GO:0035556 intracellular signal transduction;GO:0045766 positive regulation of angiogenesis;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QII0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIS5-1", "uniprot_id": [ { "id": "A0A8C2QIS5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIS5", "type": "external" } ], "mass": 90618.0, "length": 796, "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "Ppargc1a", "organism": "Hamster", "refseq_name": "peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1", "refseq_ac": [ { "id": "XP_003507827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507827", "type": "external" } ], "gene_names_uniprotkb": "Ppargc1a", "gene_names_refseq": "Ppargc1a", "protein_names_uniprotkb": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "protein_names_refseq": "peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753651)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614424.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0031625 ubiquitin protein ligase binding;GO:0031490 chromatin DNA binding;GO:0043565 sequence-specific DNA binding;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016605 PML body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0060612 adipose tissue development;GO:0097009 energy homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIV4-1", "uniprot_id": [ { "id": "A0A8C2QIV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIV4", "type": "external" } ], "mass": 59918.0, "length": 547, "protein_name": "Regulator of G-protein signaling 14", "gene_name": "Rgs14", "organism": "Hamster", "refseq_name": "regulator of G-protein signaling 14", "refseq_ac": [ { "id": "XP_003498204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498204", "type": "external" } ], "gene_names_uniprotkb": "Rgs14", "gene_names_refseq": "Rgs14", "protein_names_uniprotkb": "Regulator of G-protein signaling 14", "protein_names_refseq": "regulator of G-protein signaling 14", "tax_id": 10029, "disease": "", "pathway": " (cge:100772621)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613681.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008017 microtubule binding;GO:0001965 G-protein alpha-subunit binding;GO:0032794 GTPase activating protein binding;GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0007059 chromosome segregation;GO:0007165 signal transduction;GO:0007612 learning;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QIZ6-1", "uniprot_id": [ { "id": "A0A8C2QIZ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QIZ6", "type": "external" } ], "mass": 532611.0, "length": 4650, "protein_name": "Cytoplasmic dynein 1 heavy chain 1", "gene_name": "Dync1h1", "organism": "Hamster", "refseq_name": "cytoplasmic dynein 1 heavy chain 1 isoform X2", "refseq_ac": [ { "id": "XP_027272396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272396", "type": "external" } ], "gene_names_uniprotkb": "Dync1h1", "gene_names_refseq": "Dync1h1", "protein_names_uniprotkb": "Cytoplasmic dynein 1 heavy chain 1; Cytoplasmic dynein heavy chain 1; Dynein heavy chain, cytosolic", "protein_names_refseq": "cytoplasmic dynein 1 heavy chain 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771366)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005874 microtubule;GO:0030175 filopodium;GO:0005868 cytoplasmic dynein complex;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0051293 establishment of spindle localization;GO:0090235 regulation of metaphase plate congression;GO:1905832 positive regulation of spindle assembly;GO:0051301 cell division;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QIZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJF3-1", "uniprot_id": [ { "id": "A0A8C2QJF3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJF3", "type": "external" } ], "mass": 120617.0, "length": 1097, "protein_name": "Zinc finger E-box-binding homeobox 1", "gene_name": "Zeb1", "organism": "Hamster", "refseq_name": "zinc finger E-box-binding homeobox 1 isoform X2", "refseq_ac": [ { "id": "XP_027261264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261264", "type": "external" } ], "gene_names_uniprotkb": "Zeb1", "gene_names_refseq": "Zeb1", "protein_names_uniprotkb": "Zinc finger E-box-binding homeobox 1; Transcription factor 8", "protein_names_refseq": "zinc finger E-box-binding homeobox 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762046)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0070888 E-box binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045666 positive regulation of neuron differentiation;GO:0045602 negative regulation of endothelial cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJF3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJJ4-1", "uniprot_id": [ { "id": "A0A8C2QJJ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJJ4", "type": "external" } ], "mass": 76042.0, "length": 676, "protein_name": "WD repeat-containing protein 48", "gene_name": "Wdr48", "organism": "Hamster", "refseq_name": "WD repeat-containing protein 48 isoform X3", "refseq_ac": [ { "id": "XP_027271188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271188", "type": "external" } ], "gene_names_uniprotkb": "Wdr48", "gene_names_refseq": "Wdr48", "protein_names_uniprotkb": "WD repeat-containing protein 48; USP1-associated factor 1", "protein_names_refseq": "WD repeat-containing protein 48 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752446)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0043130 ubiquitin binding;GO:0003697 single-stranded DNA binding;GO:0035800 deubiquitinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005764 lysosome;GO:0005770 late endosome", "go_biological_process": "GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0000724 double-strand break repair via homologous recombination;GO:1905168 positive regulation of double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJL1-1", "uniprot_id": [ { "id": "A0A8C2QJL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJL1", "type": "external" } ], "mass": 51977.0, "length": 460, "protein_name": "5-hydroxytryptamine receptor 2C", "gene_name": "Htr2c", "organism": "Hamster", "refseq_name": "5-hydroxytryptamine receptor 2C", "refseq_ac": [ { "id": "XP_035305968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305968", "type": "external" } ], "gene_names_uniprotkb": "Htr2c", "gene_names_refseq": "Htr2c", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2C; Serotonin receptor 2C", "protein_names_refseq": "5-hydroxytryptamine receptor 2C", "tax_id": 10029, "disease": "", "pathway": " (cge:100754331)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding;GO:0001587 Gq/11-coupled serotonin receptor activity;GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse;GO:0098666 G protein-coupled serotonin receptor complex", "go_biological_process": "GO:0007626 locomotory behavior;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0006874 intracellular calcium ion homeostasis;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJL2-1", "uniprot_id": [ { "id": "A0A8C2QJL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJL2", "type": "external" } ], "mass": 33632.0, "length": 303, "protein_name": "Growth/differentiation factor 15", "gene_name": "LOC113833391", "organism": "Hamster", "refseq_name": "growth/differentiation factor 15-like", "refseq_ac": [ { "id": "XP_027250528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250528", "type": "external" } ], "gene_names_uniprotkb": "LOC113833391", "gene_names_refseq": "LOC113833391", "protein_names_uniprotkb": "Growth/differentiation factor 15", "protein_names_refseq": "growth/differentiation factor 15-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113833391)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005125 cytokine activity;GO:0005179 hormone activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0060400 negative regulation of growth hormone receptor signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0002686 negative regulation of leukocyte migration;GO:0040015 negative regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QJN6-1", "uniprot_id": [ { "id": "A0A8C2QJN6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QJN6", "type": "external" } ], "mass": 124778.0, "length": 1137, "protein_name": "Tyrosine-protein kinase receptor Tie-1", "gene_name": "Tie1", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase receptor Tie-1", "refseq_ac": [ { "id": "XP_003502701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502701", "type": "external" } ], "gene_names_uniprotkb": "Tie1", "gene_names_refseq": "Tie1", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor Tie-1; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase receptor Tie-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768521)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613906.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0045766 positive regulation of angiogenesis;GO:0032526 response to retinoic acid;GO:0003180 aortic valve morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QJN6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKB6-1", "uniprot_id": [ { "id": "A0A8C2QKB6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKB6", "type": "external" } ], "mass": 73058.0, "length": 643, "protein_name": "E3 ubiquitin-protein ligase AMFR", "gene_name": "Amfr", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase AMFR isoform X1", "refseq_ac": [ { "id": "XP_007642386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642386", "type": "external" } ], "gene_names_uniprotkb": "Amfr", "gene_names_refseq": "Amfr", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase AMFR; 2.3.2.36; Autocrine motility factor receptor", "protein_names_refseq": "E3 ubiquitin-protein ligase AMFR isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762626)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 378 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613984.1) and transcript sequence (IACG01065200.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007642386.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0051087 protein-folding chaperone binding;GO:0034450 ubiquitin-ubiquitin ligase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0000151 ubiquitin ligase complex;GO:0036513 Derlin-1 retrotranslocation complex", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway;GO:0051865 protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKP7-1", "uniprot_id": [ { "id": "A0A8C2QKP7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKP7", "type": "external" } ], "mass": 58292.0, "length": 527, "protein_name": "Mitogen-activated protein kinase", "gene_name": "Nlk", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase NLK isoform X1", "refseq_ac": [ { "id": "XP_016831735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831735", "type": "external" } ], "gene_names_uniprotkb": "Nlk", "gene_names_refseq": "Nlk", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "serine/threonine-protein kinase NLK isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768473)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases assembly gap :: added 135 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613601.1) and transcript sequence (IACG01090179.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0031625 ubiquitin protein ligase binding;GO:0042169 SH2 domain binding;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0050821 protein stabilization;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKP7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QKQ6-1", "uniprot_id": [ { "id": "A0A8C2QKQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QKQ6", "type": "external" } ], "mass": 146904.0, "length": 1334, "protein_name": "aldehyde oxidase", "gene_name": "LOC113830655", "organism": "Hamster", "refseq_name": "aldehyde oxidase 1 isoform X1", "refseq_ac": [ { "id": "XP_027241155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241155", "type": "external" } ], "gene_names_uniprotkb": "LOC113830655", "gene_names_refseq": "LOC113830655", "protein_names_uniprotkb": "aldehyde oxidase; 1.2.3.1", "protein_names_refseq": "aldehyde oxidase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113830655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1518 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616294.1) and transcript sequence (IACG01089155.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027241155.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.3.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0042803 protein homodimerization activity;GO:0071949 FAD binding;GO:0004031 aldehyde oxidase activity;GO:0051287 NAD binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006805 xenobiotic metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QKQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QL44-1", "uniprot_id": [ { "id": "A0A8C2QL44_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QL44", "type": "external" } ], "mass": 83360.0, "length": 740, "protein_name": "Solute carrier family 15 member 2", "gene_name": "Slc15a2", "organism": "Hamster", "refseq_name": "solute carrier family 15 member 2 isoform X1", "refseq_ac": [ { "id": "XP_027268549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268549", "type": "external" } ], "gene_names_uniprotkb": "Slc15a2", "gene_names_refseq": "Slc15a2", "protein_names_uniprotkb": "Solute carrier family 15 member 2; Kidney H(+)/peptide cotransporter; Oligopeptide transporter, kidney isoform; Peptide transporter 2", "protein_names_refseq": "solute carrier family 15 member 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766001)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1. In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate. Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs. Transports the dipeptide-like aminopeptidase inhibitor bestatin. Also able to transport carnosine. Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs). Mediates transport of bacterial peptidoglycans across the plasma membrane or, in macrophages, the phagosome membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015333 peptide:proton symporter activity;GO:0071916 dipeptide transmembrane transporter activity;GO:0015293 symporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0140206 dipeptide import across plasma membrane;GO:0140367 antibacterial innate immune response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QL44-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QL89-1", "uniprot_id": [ { "id": "A0A8C2QL89_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QL89", "type": "external" } ], "mass": 52867.0, "length": 470, "protein_name": "P2X purinoceptor", "gene_name": "P2rx5", "organism": "Hamster", "refseq_name": "P2X purinoceptor 5 isoform X2", "refseq_ac": [ { "id": "XP_027282606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282606", "type": "external" } ], "gene_names_uniprotkb": "P2rx5", "gene_names_refseq": "P2rx5", "protein_names_uniprotkb": "P2X purinoceptor; P2X purinoceptor 5", "protein_names_refseq": "P2X purinoceptor 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772284)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0001614 purinergic nucleotide receptor activity;GO:0004931 extracellularly ATP-gated monoatomic cation channel activity;GO:0099095 ligand-gated monoatomic anion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098794 postsynapse", "go_biological_process": "GO:0036179 osteoclast maturation;GO:0006821 chloride transport;GO:0070588 calcium ion transmembrane transport;GO:0033198 response to ATP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QL89-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLG7-1", "uniprot_id": [ { "id": "A0A8C2QLG7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLG7", "type": "external" } ], "mass": 100678.0, "length": 913, "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "Cbl", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase CBL isoform X2", "refseq_ac": [ { "id": "XP_027267713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267713", "type": "external" } ], "gene_names_uniprotkb": "Cbl", "gene_names_refseq": "Cbl", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase CBL; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase CBL isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754737)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0008270 zinc ion binding;GO:0017124 SH3 domain binding;GO:0046875 ephrin receptor binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005929 cilium;GO:0016600 flotillin complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0050821 protein stabilization;GO:0048260 positive regulation of receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLG7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLK7-1", "uniprot_id": [ { "id": "A0A8C2QLK7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLK7", "type": "external" } ], "mass": 194804.0, "length": 1803, "protein_name": "Methylcytosine dioxygenase TET", "gene_name": "Tet3", "organism": "Hamster", "refseq_name": "methylcytosine dioxygenase TET3 isoform X1", "refseq_ac": [ { "id": "XP_003510077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510077", "type": "external" } ], "gene_names_uniprotkb": "Tet3", "gene_names_refseq": "Tet3", "protein_names_uniprotkb": "Methylcytosine dioxygenase TET; 1.14.11.80", "protein_names_refseq": "methylcytosine dioxygenase TET3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769509)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614815.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003510077.1. COMPLETENESS: full length., [RefSeq]; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.80", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.80", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0008327 methyl-CpG binding;GO:0070579 DNA 5-methylcytosine dioxygenase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001939 female pronucleus;GO:0005694 chromosome;GO:0001940 male pronucleus;GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006493 protein O-linked glycosylation;GO:0044727 epigenetic programing of male pronucleus;GO:0141166 chromosomal 5-methylcytosine DNA demethylation pathway;GO:0040029 epigenetic regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLK7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLQ8-1", "uniprot_id": [ { "id": "A0A8C2QLQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLQ8", "type": "external" } ], "mass": 51397.0, "length": 469, "protein_name": "SHC-transforming protein 1", "gene_name": "Shc1", "organism": "Hamster", "refseq_name": "SHC-transforming protein 1 isoform X2", "refseq_ac": [ { "id": "XP_003501645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501645", "type": "external" } ], "gene_names_uniprotkb": "Shc1", "gene_names_refseq": "Shc1", "protein_names_uniprotkb": "SHC-transforming protein 1; Src homology 2 domain-containing-transforming protein C1", "protein_names_refseq": "SHC-transforming protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613854.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005158 insulin receptor binding;GO:0046875 ephrin receptor binding;GO:0005159 insulin-like growth factor receptor binding;GO:0005168 neurotrophin TRKA receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043066 negative regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLQ8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QLT0-1", "uniprot_id": [ { "id": "A0A8C2QLT0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QLT0", "type": "external" } ], "mass": 106769.0, "length": 975, "protein_name": "Serine/threonine-protein kinase Nek9", "gene_name": "Nek9", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase Nek9 isoform X1", "refseq_ac": [ { "id": "XP_007641583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641583", "type": "external" } ], "gene_names_uniprotkb": "Nek9", "gene_names_refseq": "Nek9", "protein_names_uniprotkb": "Serine/threonine-protein kinase Nek9; 2.7.11.38; Nercc1 kinase; Never in mitosis A-related kinase 9", "protein_names_refseq": "serine/threonine-protein kinase Nek9 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759330)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 330 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613913.1) and transcript sequence (IACG01048651.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007641583.2. COMPLETENESS: full length., [RefSeq]; Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QLT0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ18-1", "uniprot_id": [ { "id": "A0A9J7FZ18_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ18", "type": "external" } ], "mass": 112808.0, "length": 1055, "protein_name": "Serine/threonine-protein kinase", "gene_name": "Ulk1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase ULK1 isoform X2", "refseq_ac": [ { "id": "XP_027271704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271704", "type": "external" } ], "gene_names_uniprotkb": "Ulk1", "gene_names_refseq": "Ulk1", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase ULK1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772932)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase involved in autophagy in response to starvation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": 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"A0A8C2QMD2-1", "uniprot_id": [ { "id": "A0A8C2QMD2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMD2", "type": "external" } ], "mass": 53925.0, "length": 496, "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "Wasf2", "organism": "Hamster", "refseq_name": "wiskott-Aldrich syndrome protein family member 2", "refseq_ac": [ { "id": "XP_027255353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255353", "type": "external" } ], "gene_names_uniprotkb": "Wasf2", "gene_names_refseq": "Wasf2", "protein_names_uniprotkb": "Wiskott-Aldrich syndrome protein family member; WASP family protein member", "protein_names_refseq": "wiskott-Aldrich syndrome protein family member 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759260)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0034185 apolipoprotein binding;GO:0005509 calcium ion binding;GO:0042562 hormone binding", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0043235 receptor complex;GO:0016324 apical plasma membrane;GO:0034361 very-low-density lipoprotein particle", "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FEE4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMW2-1", "uniprot_id": [ { "id": "A0A8C2QMW2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMW2", "type": "external" } ], "mass": 20282.0, "length": 201, "protein_name": "Cbp/p300-interacting transactivator 1", "gene_name": "Cited1", "organism": "Hamster", "refseq_name": "cbp/p300-interacting transactivator 1", "refseq_ac": [ { "id": "XP_027287598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287598", "type": "external" } ], "gene_names_uniprotkb": "Cited1", "gene_names_refseq": "Cited1", "protein_names_uniprotkb": "Cbp/p300-interacting transactivator 1", "protein_names_refseq": "cbp/p300-interacting transactivator 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759164)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050693 LBD domain binding;GO:0070410 co-SMAD binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0070669 response to interleukin-2;GO:0071104 response to interleukin-9;GO:0071105 response to interleukin-11;GO:0006351 DNA-templated transcription;GO:0006913 nucleocytoplasmic transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QMW3-1", "uniprot_id": [ { "id": "A0A8C2QMW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QMW3", "type": "external" } ], "mass": 70372.0, "length": 620, "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "Slc27a2", "organism": "Hamster", "refseq_name": "very long-chain acyl-CoA synthetase isoform X2", "refseq_ac": [ { "id": "XP_027277730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277730", "type": "external" } ], "gene_names_uniprotkb": "Slc27a2", "gene_names_refseq": "Slc27a2", "protein_names_uniprotkb": "long-chain-fatty-acid--CoA ligase; 6.2.1.3; Long-chain-fatty-acid--CoA ligase", "protein_names_refseq": "very long-chain acyl-CoA synthetase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754190)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "6.2.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.76", "type": "external" } ], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0019899 enzyme binding;GO:0000166 nucleotide binding;GO:0004467 long-chain fatty acid-CoA ligase activity;GO:0031957 very long-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0005788 endoplasmic reticulum lumen;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0006699 bile acid biosynthetic process;GO:0044539 long-chain fatty acid import into cell;GO:0001561 fatty acid alpha-oxidation;GO:0097089 methyl-branched fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QMW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNA4-1", "uniprot_id": [ { "id": "A0A8C2QNA4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNA4", "type": "external" } ], "mass": 119021.0, "length": 1106, "protein_name": "Angiomotin isoform X2", "gene_name": "Amot", "organism": "Hamster", "refseq_name": "angiomotin isoform X2", "refseq_ac": [ { "id": "XP_027289417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289417", "type": "external" } ], "gene_names_uniprotkb": "Amot", "gene_names_refseq": "Amot", "protein_names_uniprotkb": "Angiomotin isoform X2", "protein_names_refseq": "angiomotin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769669)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043532 angiostatin binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005884 actin filament;GO:0005923 bicellular tight junction;GO:0030027 lamellipodium;GO:0009897 external side of plasma membrane;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001525 angiogenesis;GO:0035329 hippo signaling;GO:0030036 actin cytoskeleton organization;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNA4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNG9-1", "uniprot_id": [ { "id": "A0A8C2QNG9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNG9", "type": "external" } ], "mass": 32944.0, "length": 298, "protein_name": "Homeobox protein SIX2 isoform X2", "gene_name": "Six2", "organism": "Hamster", "refseq_name": "homeobox protein SIX2 isoform X2", "refseq_ac": [ { "id": "XP_027273932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273932", "type": "external" } ], "gene_names_uniprotkb": "Six2", "gene_names_refseq": "Six2", "protein_names_uniprotkb": "Homeobox protein SIX2 isoform X2", "protein_names_refseq": "homeobox protein SIX2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767057)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0007501 mesodermal cell fate specification;GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis;GO:0090189 regulation of branching involved in ureteric bud morphogenesis;GO:0097168 mesenchymal stem cell proliferation;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNK6-1", "uniprot_id": [ { "id": "A0A8C2QNK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNK6", "type": "external" } ], "mass": 110051.0, "length": 1006, "protein_name": "E3 ubiquitin-protein ligase MIB1", "gene_name": "Mib1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase MIB1 isoform X2", "refseq_ac": [ { "id": "XP_027260124", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260124", "type": "external" } ], "gene_names_uniprotkb": "Mib1", "gene_names_refseq": "Mib1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MIB1; 2.3.2.27; DAPK-interacting protein 1; E3 ubiquitin-protein ligase mib1; Mind bomb homolog 1; RING-type E3 ubiquitin transferase MIB1", "protein_names_refseq": "E3 ubiquitin-protein ligase MIB1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766406)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0014069 postsynaptic density;GO:0031410 cytoplasmic vesicle;GO:0034451 centriolar satellite", "go_biological_process": "GO:0006897 endocytosis;GO:0007219 Notch signaling pathway;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNK6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QNX0-1", "uniprot_id": [ { "id": "A0A8C2QNX0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QNX0", "type": "external" } ], "mass": 15032.0, "length": 137, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 7", "gene_name": "Snapin", "organism": "Hamster", "refseq_name": "SNARE-associated protein Snapin isoform X1", "refseq_ac": [ { "id": "XP_003501710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501710", "type": "external" } ], "gene_names_uniprotkb": "Snapin", "gene_names_refseq": "Snapin", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit 7", "protein_names_refseq": "SNARE-associated protein Snapin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100752727)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 88 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613854.1) and transcript sequence (JI868142.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003501710.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0000149 SNARE binding", "go_cellular_component": "GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0001669 acrosomal vesicle;GO:0002177 manchette;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0010977 negative regulation of neuron projection development;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport;GO:0048490 anterograde synaptic vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QNX0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP73-1", "uniprot_id": [ { "id": "A0A8C2QP73_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP73", "type": "external" } ], "mass": 51405.0, "length": 476, "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "gene_name": "Coq6", "organism": "Hamster", "refseq_name": "ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "refseq_ac": [ { "id": "XP_003505185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505185", "type": "external" } ], "gene_names_uniprotkb": "Coq6; COQ6", "gene_names_refseq": "Coq6", "protein_names_uniprotkb": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; 1.14.15.45; 1.14.15.46; 2-methoxy-6-polyprenolphenol 4-hydroxylase; Coenzyme Q10 monooxygenase 6", "protein_names_refseq": "ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100751162)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614123.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-decaprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid. Also acts downstream of COQ4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-decaprenyl)phenol to 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to COQ6 from NADPH via a ferredoxin/ferredoxin reductase system composed of FDX2 and FDXR., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.15.45", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.45", "type": "external" }, { "id": "1.14.15.46", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.46", "type": "external" } ], "go_molecular_function": "GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0071949 FAD binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0106364 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity;GO:0120538 2-methoxy-6-polyprenolphenol 4-hydroxylase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005794 Golgi apparatus;GO:0042995 cell projection", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP73-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QP92-1", "uniprot_id": [ { "id": "A0A8C2QP92_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QP92", "type": "external" } ], "mass": 151520.0, "length": 1342, "protein_name": "WD repeat-containing protein 19", "gene_name": "LOC100758043", "organism": "Hamster", "refseq_name": "WD repeat-containing protein 19 isoform X2", "refseq_ac": [ { "id": "XP_007651849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651849", "type": "external" } ], "gene_names_uniprotkb": "LOC100758043", "gene_names_refseq": "LOC100758043", "protein_names_uniprotkb": "WD repeat-containing protein 19; Intraflagellar transport 144 homolog", "protein_names_refseq": "WD repeat-containing protein 19 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758043)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 854 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615881.1) and transcript sequence (JI891580.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly. Essential for functional IFT-A assembly and ciliary entry of GPCRs. Associates with the BBSome complex to mediate ciliary transport., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0097228 sperm principal piece;GO:0032391 photoreceptor connecting cilium;GO:0001750 photoreceptor outer segment;GO:0097225 sperm midpiece;GO:0030991 intraciliary transport particle A", "go_biological_process": "GO:0060271 cilium assembly;GO:0097499 protein localization to non-motile cilium;GO:1903441 protein localization to ciliary membrane;GO:0035721 intraciliary retrograde transport;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QP92-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPC0-1", "uniprot_id": [ { "id": "A0A8C2QPC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPC0", "type": "external" } ], "mass": 51055.0, "length": 465, "protein_name": "One cut domain family member", "gene_name": "Onecut1", "organism": "Hamster", "refseq_name": "hepatocyte nuclear factor 6", "refseq_ac": [ { "id": "XP_027266958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266958", "type": "external" } ], "gene_names_uniprotkb": "Onecut1", "gene_names_refseq": "Onecut1", "protein_names_uniprotkb": "One cut domain family member", "protein_names_refseq": "hepatocyte nuclear factor 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100765766)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPF5-1", "uniprot_id": [ { "id": "A0A8C2QPF5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPF5", "type": "external" } ], "mass": 60768.0, "length": 551, "protein_name": "SH2B adapter protein 3", "gene_name": "Sh2b3", "organism": "Hamster", "refseq_name": "SH2B adapter protein 3 isoform X1", "refseq_ac": [ { "id": "XP_007626498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007626498", "type": "external" } ], "gene_names_uniprotkb": "Sh2b3", "gene_names_refseq": "Sh2b3", "protein_names_uniprotkb": "SH2B adapter protein 3; Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; Signal transduction protein Lnk", "protein_names_refseq": "SH2B adapter protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773100)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 481 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613692.1) and transcript sequence (IACG01024030.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007626498.2. COMPLETENESS: full length., [RefSeq]; Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005173 stem cell factor receptor binding;GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0070100 negative regulation of chemokine-mediated signaling pathway;GO:0008285 negative regulation of cell population proliferation;GO:0035556 intracellular signal transduction;GO:0035855 megakaryocyte development;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPN7-1", "uniprot_id": [ { "id": "A0A8C2QPN7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPN7", "type": "external" } ], "mass": 137875.0, "length": 1332, "protein_name": "Insulin receptor substrate 2", "gene_name": "Irs2", "organism": "Hamster", "refseq_name": "insulin receptor substrate 2 isoform X2", "refseq_ac": [ { "id": "XP_027243682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243682", "type": "external" } ], "gene_names_uniprotkb": "Irs2", "gene_names_refseq": "Irs2", "protein_names_uniprotkb": "Insulin receptor substrate 2", "protein_names_refseq": "insulin receptor substrate 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771848)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0043548 phosphatidylinositol 3-kinase binding;GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity;GO:0141038 phosphatidylinositol 3-kinase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0032000 positive regulation of fatty acid beta-oxidation;GO:0032024 positive regulation of insulin secretion;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0030890 positive regulation of B cell proliferation;GO:0008286 insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPN7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPR3-1", "uniprot_id": [ { "id": "A0A8C2QPR3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPR3", "type": "external" } ], "mass": 33108.0, "length": 289, "protein_name": "Programmed cell death 1 ligand 1", "gene_name": "Cd274", "organism": "Hamster", "refseq_name": "programmed cell death 1 ligand 1", "refseq_ac": [ { "id": "XP_035297785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297785", "type": "external" } ], "gene_names_uniprotkb": "Cd274", "gene_names_refseq": "Cd274", "protein_names_uniprotkb": "Programmed cell death 1 ligand 1; B7 homolog 1", "protein_names_refseq": "programmed cell death 1 ligand 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759180)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The PDCD1-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and escape destruction by the immune system, thereby facilitating tumor survival. The interaction with PDCD1/PD-1 inhibits cytotoxic T lymphocytes (CTLs) effector function. The blockage of the PDCD1-mediated pathway results in the reversal of the exhausted T-cell phenotype and the normalization of the anti-tumor response, providing a rationale for cancer immunotherapy., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0016607 nuclear speck;GO:0070062 extracellular exosome;GO:0009897 external side of plasma membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0032693 negative regulation of interleukin-10 production;GO:0007166 cell surface receptor signaling pathway;GO:0031295 T cell costimulation;GO:0032689 negative regulation of type II interferon production;GO:0071222 cellular response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QPX9-1", "uniprot_id": [ { "id": "A0A8C2QPX9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QPX9", "type": "external" } ], "mass": 102301.0, "length": 939, "protein_name": "Kinase", "gene_name": "Itpkb", "organism": "Hamster", "refseq_name": "inositol-trisphosphate 3-kinase B isoform X1", "refseq_ac": [ { "id": "XP_003507272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507272", "type": "external" } ], "gene_names_uniprotkb": "Itpkb", "gene_names_refseq": "Itpkb", "protein_names_uniprotkb": "Kinase; 2.7.-.-", "protein_names_refseq": "inositol-trisphosphate 3-kinase B isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774983)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 920 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614340.1) and transcript sequence (IACG01051064.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003507272.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.-.-", "type": "external" } ], "go_molecular_function": "GO:0000828 inositol hexakisphosphate kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0071277 cellular response to calcium ion;GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0032957 inositol trisphosphate metabolic process;GO:0032958 inositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QPX9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2QQ35-1", "uniprot_id": [ { "id": "A0A8C2QQ35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2QQ35", "type": "external" } ], "mass": 74334.0, "length": 673, "protein_name": "Zinc finger and BTB domain-containing protein 16 isoform X3", "gene_name": "Zbtb16", "organism": "Hamster", "refseq_name": "zinc finger and BTB domain-containing protein 16 isoform X3", "refseq_ac": [ { "id": "XP_035300543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300543", "type": "external" } ], "gene_names_uniprotkb": "Zbtb16", "gene_names_refseq": "Zbtb16", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 16 isoform X3", "protein_names_refseq": "zinc finger and BTB domain-containing protein 16 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100769421)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001222 transcription corepressor binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0017053 transcription repressor complex;GO:0016605 PML body;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045600 positive regulation of fat cell differentiation;GO:0007417 central nervous system development;GO:0045893 positive regulation of DNA-templated transcription;GO:0030097 hemopoiesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2QQ35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7CHB0-1", "uniprot_id": [ { "id": "A0A9J7CHB0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7CHB0", "type": "external" } ], "mass": 29584.0, "length": 257, "protein_name": "Iodothyronine deiodinase", "gene_name": "Dio1", "organism": "Hamster", "refseq_name": "type I iodothyronine deiodinase", "refseq_ac": [ { "id": "NP_001243688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243688", "type": "external" } ], "gene_names_uniprotkb": "Dio1", "gene_names_refseq": "Dio1", "protein_names_uniprotkb": "Iodothyronine deiodinase", "protein_names_refseq": "deiodinase, iodothyronine type I; type I iodothyronine deiodinase", "tax_id": 10029, "disease": "", "pathway": " (cge:100765192)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN04501062, SAMN09948095 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AFTD01005900.1. On Feb 19, 2012 this sequence version replaced XP_003495773.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033798 thyroxine 5-deiodinase activity;GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042404 thyroid hormone catabolic process;GO:0042446 hormone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7CHB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZN4-1", "uniprot_id": [ { "id": "A0A9J7EZN4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZN4", "type": "external" } ], "mass": 42233.0, "length": 360, "protein_name": "Alpha-2-macroglobulin receptor-associated protein", "gene_name": "Lrpap1", "organism": "Hamster", "refseq_name": "alpha-2-macroglobulin receptor-associated protein isoform X1", "refseq_ac": [ { "id": "XP_027242926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242926", "type": "external" } ], "gene_names_uniprotkb": "Lrpap1", "gene_names_refseq": "Lrpap1", "protein_names_uniprotkb": "Alpha-2-macroglobulin receptor-associated protein; Low density lipoprotein receptor-related protein-associated protein 1", "protein_names_refseq": "alpha-2-macroglobulin receptor-associated protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766187)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0048019 receptor antagonist activity;GO:0035473 lipase binding;GO:0070326 very-low-density lipoprotein particle receptor binding", "go_cellular_component": "GO:0005796 Golgi lumen;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031904 endosome lumen;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0002091 negative regulation of receptor internalization;GO:0010916 negative regulation of very-low-density lipoprotein particle clearance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EWD9-1", "uniprot_id": [ { "id": "A0A9J7EWD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EWD9", "type": "external" } ], "mass": 56526.0, "length": 507, "protein_name": "Group 3 secretory phospholipase A2", "gene_name": "Pla2g3", "organism": "Hamster", "refseq_name": "group 3 secretory phospholipase A2", "refseq_ac": [ { "id": "XP_027243080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243080", "type": "external" } ], "gene_names_uniprotkb": "Pla2g3", "gene_names_refseq": "Pla2g3", "protein_names_uniprotkb": "Group 3 secretory phospholipase A2; 3.1.1.4; Group III secretory phospholipase A2; Phosphatidylcholine 2-acylhydrolase 3", "protein_names_refseq": "group 3 secretory phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761489)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0005814 centriole", "go_biological_process": "GO:0010629 negative regulation of gene expression;GO:0010976 positive regulation of neuron projection development;GO:0050482 arachidonate secretion;GO:0045597 positive regulation of cell differentiation;GO:0046470 phosphatidylcholine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EWD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F492-1", "uniprot_id": [ { "id": "A0A9J7F492_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F492", "type": "external" } ], "mass": 109434.0, "length": 977, "protein_name": "Mast/stem cell growth factor receptor", "gene_name": "Kit", "organism": "Hamster", "refseq_name": "mast/stem cell growth factor receptor Kit isoform X3", "refseq_ac": [ { "id": "XP_027246711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246711", "type": "external" } ], "gene_names_uniprotkb": "Kit", "gene_names_refseq": "Kit", "protein_names_uniprotkb": "Mast/stem cell growth factor receptor; 2.7.10.1", "protein_names_refseq": "mast/stem cell growth factor receptor Kit isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751027)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0038093 Fc receptor signaling pathway;GO:0006935 chemotaxis;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F492-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F4T8-1", "uniprot_id": [ { "id": "A0A9J7F4T8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F4T8", "type": "external" } ], "mass": 61349.0, "length": 572, "protein_name": "Inosine-5'-monophosphate dehydrogenase", "gene_name": "Impdh1", "organism": "Hamster", "refseq_name": "inosine-5'-monophosphate dehydrogenase 1 isoform X2", "refseq_ac": [ { "id": "XP_027247134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247134", "type": "external" } ], "gene_names_uniprotkb": "Impdh1; IMPDH", "gene_names_refseq": "Impdh1", "protein_names_uniprotkb": "Inosine-5'-monophosphate dehydrogenase; 1.1.1.205; IMP dehydrogenase; IMPDH; IMPD", "protein_names_refseq": "inosine-5'-monophosphate dehydrogenase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760550)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0003938 IMP dehydrogenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006177 GMP biosynthetic process;GO:0006183 GTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F4T8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZT7-1", "uniprot_id": [ { "id": "A0A9J7EZT7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZT7", "type": "external" } ], "mass": 173713.0, "length": 1554, "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "Abcc1", "organism": "Hamster", "refseq_name": "multidrug resistance-associated protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027243493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243493", "type": "external" } ], "gene_names_uniprotkb": "Abcc1", "gene_names_refseq": "Abcc1", "protein_names_uniprotkb": "Multidrug resistance-associated protein 1; 7.6.2.2; 7.6.2.3; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter", "protein_names_refseq": "multidrug resistance-associated protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689208)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015431 ABC-type glutathione S-conjugate transporter activity;GO:0034634 glutathione transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZT7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7EZ99-1", "uniprot_id": [ { "id": "A0A9J7EZ99_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7EZ99", "type": "external" } ], "mass": 61431.0, "length": 535, "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "gene_name": "Mgat4a", "organism": "Hamster", "refseq_name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform X1", "refseq_ac": [ { "id": "XP_027242633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242633", "type": "external" } ], "gene_names_uniprotkb": "Mgat4a", "gene_names_refseq": "Mgat4a", "protein_names_uniprotkb": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A; 2.4.1.145; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa", "protein_names_refseq": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766200)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.145", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.145", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005795 Golgi stack;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7EZ99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F2A1-1", "uniprot_id": [ { "id": "A0A9J7F2A1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F2A1", "type": "external" } ], "mass": 154018.0, "length": 1407, "protein_name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2", "gene_name": "Magi2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X3", "refseq_ac": [ { "id": "XP_027249261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249261", "type": "external" } ], "gene_names_uniprotkb": "Magi2", "gene_names_refseq": "Magi2", "protein_names_uniprotkb": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; Atrophin-1-interacting protein 1; Membrane-associated guanylate kinase inverted 2", "protein_names_refseq": "LOW QUALITY PROTEIN: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100759337)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070699 type II activin receptor binding;GO:0046332 SMAD binding;GO:0016301 kinase activity;GO:0030159 signaling receptor complex adaptor activity;GO:0031697 beta-1 adrenergic receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0030425 dendrite;GO:0045202 synapse;GO:0005770 late endosome", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0043113 receptor clustering;GO:0099173 postsynapse organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F2A1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F377-1", "uniprot_id": [ { "id": "A0A9J7F377_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F377", "type": "external" } ], "mass": 79059.0, "length": 683, "protein_name": "Cyclic nucleotide-gated channel alpha-1", "gene_name": "Cnga1", "organism": "Hamster", "refseq_name": "cGMP-gated cation channel alpha-1 isoform X2", "refseq_ac": [ { "id": "XP_027246653", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246653", "type": "external" } ], "gene_names_uniprotkb": "Cnga1", "gene_names_refseq": "Cnga1", "protein_names_uniprotkb": "Cyclic nucleotide-gated channel alpha-1; Cyclic nucleotide-gated cation channel 1; Cyclic nucleotide-gated channel, photoreceptor; Rod photoreceptor cGMP-gated cation channel subunit alpha; cGMP-gated cation channel alpha-1", "protein_names_refseq": "cGMP-gated cation channel alpha-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768599)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pore-forming subunit of the rod cyclic nucleotide-gated channel. Mediates rod photoresponses at dim light converting transient changes in intracellular cGMP levels into electrical signals. In the dark, cGMP levels are high and keep the channel open enabling a steady inward current carried by Na(+) and Ca(2+) ions that leads to membrane depolarization and neurotransmitter release from synaptic terminals. Upon photon absorption cGMP levels decline leading to channel closure and membrane hyperpolarization that ultimately slows neurotransmitter release and signals the presence of light, the end point of the phototransduction cascade. Conducts cGMP- and cAMP-gated ion currents, with permeability for monovalent and divalent cations. The selectivity for Ca(2+) over Na(+) increases with cGMP concentrations, whereas the selectivity among monovalent ions is independent of the cGMP levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0044877 protein-containing complex binding;GO:0005223 intracellularly cGMP-activated cation channel activity;GO:0005272 sodium channel activity;GO:0005222 intracellularly cAMP-activated cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0017071 intracellular cyclic nucleotide activated cation channel complex;GO:0120025 plasma membrane bounded cell projection", "go_biological_process": "GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F377-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F3T3-1", "uniprot_id": [ { "id": "A0A9J7F3T3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F3T3", "type": "external" } ], "mass": 13626.0, "length": 120, "protein_name": "Protein S100", "gene_name": "LOC100773174", "organism": "Hamster", "refseq_name": "protein S100-A9", "refseq_ac": [ { "id": "XP_003511344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511344", "type": "external" } ], "gene_names_uniprotkb": "LOC100773174", "gene_names_refseq": "LOC100773174", "protein_names_uniprotkb": "Protein S100; S100 calcium-binding protein", "protein_names_refseq": "protein S100-A9", "tax_id": 10029, "disease": "", "pathway": " (cge:100773174)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615070.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding;GO:0016209 antioxidant activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0032496 response to lipopolysaccharide;GO:0045087 innate immune response;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0006915 apoptotic process;GO:0002523 leukocyte migration involved in inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F3T3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F4C8-1", "uniprot_id": [ { "id": "A0A9J7F4C8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F4C8", "type": "external" } ], "mass": 16493.0, "length": 147, "protein_name": "Microsomal glutathione S-transferase 2", "gene_name": "Mgst2", "organism": "Hamster", "refseq_name": "microsomal glutathione S-transferase 2", "refseq_ac": [ { "id": "XP_027250746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250746", "type": "external" } ], "gene_names_uniprotkb": "Mgst2", "gene_names_refseq": "Mgst2", "protein_names_uniprotkb": "Microsomal glutathione S-transferase 2; 1.11.1.-; 2.5.1.18; 4.4.1.20; Glutathione peroxidase MGST2; Leukotriene C4 synthase MGST2; Microsomal GST-2; Microsomal GST-II; Microsomal glutathione S-transferase II", "protein_names_refseq": "microsomal glutathione S-transferase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764249)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" }, { "id": "5.3.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.2", "type": "external" }, { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" }, { "id": "1.20.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.20.4.2", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0043295 glutathione binding;GO:0004464 leukotriene-C4 synthase activity;GO:0008047 enzyme activator activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0019370 leukotriene biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F4C8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F4P4-1", "uniprot_id": [ { "id": "A0A9J7F4P4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F4P4", "type": "external" } ], "mass": 92846.0, "length": 835, "protein_name": "Serine/threonine-protein kinase TNNI3K", "gene_name": "Tnni3k", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase TNNI3K", "refseq_ac": [ { "id": "XP_027250993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250993", "type": "external" } ], "gene_names_uniprotkb": "Tnni3k", "gene_names_refseq": "Tnni3k", "protein_names_uniprotkb": "Serine/threonine-protein kinase TNNI3K; 2.7.11.1; Cardiac ankyrin repeat kinase; TNNI3-interacting kinase", "protein_names_refseq": "serine/threonine-protein kinase TNNI3K", "tax_id": 10029, "disease": "", "pathway": " (cge:100768825)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in cardiac physiology., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:1903779 regulation of cardiac conduction;GO:0002027 regulation of heart rate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F4P4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F4U9-1", "uniprot_id": [ { "id": "A0A9J7F4U9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F4U9", "type": "external" } ], "mass": 91997.0, "length": 822, "protein_name": "Fibroblast growth factor receptor", "gene_name": "Fgfr1", "organism": "Hamster", "refseq_name": "fibroblast growth factor receptor 1 isoform X1", "refseq_ac": [ { "id": "XP_027251131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251131", "type": "external" } ], "gene_names_uniprotkb": "Fgfr1", "gene_names_refseq": "Fgfr1", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "fibroblast growth factor receptor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773586)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0008201 heparin binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:0045597 positive regulation of cell differentiation;GO:0072091 regulation of stem cell proliferation;GO:0010604 positive regulation of macromolecule metabolic process;GO:0002053 positive regulation of mesenchymal cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F4U9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F595-1", "uniprot_id": [ { "id": "A0A9J7F595_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F595", "type": "external" } ], "mass": 257185.0, "length": 2301, "protein_name": "Phosphatidylinositol phosphatase PTPRQ", "gene_name": "Ptprq", "organism": "Hamster", "refseq_name": "phosphatidylinositol phosphatase PTPRQ isoform X3", "refseq_ac": [ { "id": "XP_027248266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248266", "type": "external" } ], "gene_names_uniprotkb": "Ptprq", "gene_names_refseq": "Ptprq", "protein_names_uniprotkb": "Phosphatidylinositol phosphatase PTPRQ; 3.1.3.36; 3.1.3.67; 3.1.3.86; 3.1.3.95; Receptor-type tyrosine-protein phosphatase Q", "protein_names_refseq": "phosphatidylinositol phosphatase PTPRQ isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100774028)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0004725 protein tyrosine phosphatase activity;GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0016324 apical plasma membrane;GO:0009925 basal plasma membrane;GO:0032420 stereocilium", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F595-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F5B9-1", "uniprot_id": [ { "id": "A0A9J7F5B9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F5B9", "type": "external" } ], "mass": 540684.0, "length": 4981, "protein_name": "Protocadherin Fat 4", "gene_name": "Fat4", "organism": "Hamster", "refseq_name": "protocadherin Fat 4", "refseq_ac": [ { "id": "XP_027247746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247746", "type": "external" } ], "gene_names_uniprotkb": "Fat4", "gene_names_refseq": "Fat4", "protein_names_uniprotkb": "Protocadherin Fat 4; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J", "protein_names_refseq": "protocadherin Fat 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100769423)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0043931 ossification involved in bone maturation;GO:0072137 condensed mesenchymal cell proliferation;GO:0035329 hippo signaling;GO:0003007 heart morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F5B9-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAV6-1", "uniprot_id": [ { "id": "A0A9J7FAV6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAV6", "type": "external" } ], "mass": 51097.0, "length": 454, "protein_name": "Kynurenine--oxoglutarate transaminase 3", "gene_name": "Kyat3", "organism": "Hamster", "refseq_name": "kynurenine--oxoglutarate transaminase 3 isoform X1", "refseq_ac": [ { "id": "XP_003515282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515282", "type": "external" } ], "gene_names_uniprotkb": "Kyat3", "gene_names_refseq": "Kyat3", "protein_names_uniprotkb": "Kynurenine--oxoglutarate transaminase 3; 2.6.1.63; 2.6.1.7; 4.4.1.13; Cysteine-S-conjugate beta-lyase 2; Kynurenine aminotransferase 3; Kynurenine aminotransferase III; Kynurenine--glyoxylate transaminase; Kynurenine--oxoglutarate transaminase III", "protein_names_refseq": "kynurenine--oxoglutarate transaminase 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771070)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 598 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617583.1) and transcript sequence (JP063262.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003515282.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.64", "type": "external" }, { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.63", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.63", "type": "external" }, { "id": "2.6.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.39", "type": "external" }, { "id": "2.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.4", "type": "external" }, { "id": "2.6.1.73", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.73", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0047315 kynurenine-glyoxylate transaminase activity;GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0047804 cysteine-S-conjugate beta-lyase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070189 kynurenine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F5U8-1", "uniprot_id": [ { "id": "A0A9J7F5U8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F5U8", "type": "external" } ], "mass": 67897.0, "length": 599, "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "Irak3", "organism": "Hamster", "refseq_name": "interleukin-1 receptor-associated kinase 3", "refseq_ac": [ { "id": "XP_027248122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248122", "type": "external" } ], "gene_names_uniprotkb": "Irak3", "gene_names_refseq": "Irak3", "protein_names_uniprotkb": "Interleukin-1 receptor-associated kinase 3; IL-1 receptor-associated kinase M; Inactive IL-1 receptor-associated kinase 3", "protein_names_refseq": "interleukin-1 receptor-associated kinase 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767434)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0001960 negative regulation of cytokine-mediated signaling pathway;GO:0070498 interleukin-1-mediated signaling pathway;GO:0032496 response to lipopolysaccharide;GO:0032715 negative regulation of interleukin-6 production;GO:0032720 negative regulation of tumor necrosis factor production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F5U8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F738-1", "uniprot_id": [ { "id": "A0A9J7F738_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F738", "type": "external" } ], "mass": 61080.0, "length": 533, "protein_name": "Retinoid isomerohydrolase", "gene_name": "Rpe65", "organism": "Hamster", "refseq_name": "retinoid isomerohydrolase", "refseq_ac": [ { "id": "XP_003507726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507726", "type": "external" } ], "gene_names_uniprotkb": "Rpe65", "gene_names_refseq": "Rpe65", "protein_names_uniprotkb": "Retinoid isomerohydrolase; 3.1.1.64; 5.3.3.22; All-trans-retinyl-palmitate hydrolase; Lutein isomerase; Meso-zeaxanthin isomerase; Retinal pigment epithelium-specific 65 kDa protein; Retinol isomerase", "protein_names_refseq": "retinoid isomerohydrolase", "tax_id": 10029, "disease": "", "pathway": " (cge:100767488)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614413.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors. Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.64", "type": "external" }, { "id": "5.3.3.22", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.22", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003834 beta-carotene 15,15'-dioxygenase activity;GO:0052885 all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity;GO:0050251 retinol isomerase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007601 visual perception;GO:0042574 retinal metabolic process;GO:1901827 zeaxanthin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F738-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F7S0-1", "uniprot_id": [ { "id": "A0A9J7F7S0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F7S0", "type": "external" } ], "mass": 59992.0, "length": 532, "protein_name": "Cytochrome P450", "gene_name": "LOC100761779", "organism": "Hamster", "refseq_name": "cytochrome P450 2U1 isoform X3", "refseq_ac": [ { "id": "XP_027251521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251521", "type": "external" } ], "gene_names_uniprotkb": "LOC100761779", "gene_names_refseq": "LOC100761779", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.-", "protein_names_refseq": "cytochrome P450 2U1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761779)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels. Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin., [UniProtKB, UniProtKB]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008395 steroid hydroxylase activity;GO:0102033 long-chain fatty acid omega-hydroxylase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F7S0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F7Y3-1", "uniprot_id": [ { "id": "A0A9J7F7Y3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F7Y3", "type": "external" } ], "mass": 46736.0, "length": 424, "protein_name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "Acadm", "organism": "Hamster", "refseq_name": "medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027250982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250982", "type": "external" } ], "gene_names_uniprotkb": "Acadm", "gene_names_refseq": "Acadm", "protein_names_uniprotkb": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; 1.3.8.7", "protein_names_refseq": "medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763159)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation (FAO), breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of FAO consists in the proR-proR stereospecific alpha, beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA). ETF is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase has preference for fatty acyl-CoAs with saturated 6 to 12 carbons long primary chains, making it but can also catalyze longer chains such as C14 and C16., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.8.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.1", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "1.3.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.7", "type": "external" }, { "id": "1.3.8.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.8", "type": "external" }, { "id": "1.3.8.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.4", "type": "external" }, { "id": "1.3.8.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.9", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0051793 medium-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F7Y3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7F9H9-1", "uniprot_id": [ { "id": "A0A9J7F9H9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7F9H9", "type": "external" } ], "mass": 34381.0, "length": 314, "protein_name": "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial", "gene_name": "Hadh", "organism": "Hamster", "refseq_name": "hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_007648452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648452", "type": "external" } ], "gene_names_uniprotkb": "Hadh", "gene_names_refseq": "Hadh", "protein_names_uniprotkb": "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; 1.1.1.35; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase", "protein_names_refseq": "hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761491)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 482 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614745.1) and transcript sequence (IACG01063192.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007648452.1. COMPLETENESS: full length., [RefSeq]; Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "4.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.17", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "1.1.1.211", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.211", "type": "external" }, { "id": "1.1.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62", "type": "external" }, { "id": "1.1.1.239", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.239", "type": "external" }, { "id": "1.1.1.178", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.178", "type": "external" }, { "id": "1.1.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.53", "type": "external" }, { "id": "1.1.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.159", "type": "external" } ], "go_molecular_function": "GO:0070403 NAD+ binding;GO:0003857 (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0050796 regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7F9H9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FAB9-1", "uniprot_id": [ { "id": "A0A9J7FAB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FAB9", "type": "external" } ], "mass": 133806.0, "length": 1224, "protein_name": "Pro-epidermal growth factor", "gene_name": "Egf", "organism": "Hamster", "refseq_name": "pro-epidermal growth factor isoform X2", "refseq_ac": [ { "id": "XP_027251495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251495", "type": "external" } ], "gene_names_uniprotkb": "Egf", "gene_names_refseq": "Egf", "protein_names_uniprotkb": "Pro-epidermal growth factor", "protein_names_refseq": "pro-epidermal growth factor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763146)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005154 epidermal growth factor receptor binding;GO:0017147 Wnt-protein binding;GO:0008083 growth factor activity;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0048731 system development;GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FAB9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBI2-1", "uniprot_id": [ { "id": "A0A9J7FBI2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBI2", "type": "external" } ], "mass": 60989.0, "length": 573, "protein_name": "60 kDa heat shock protein, mitochondrial", "gene_name": "Hspd1", "organism": "Hamster", "refseq_name": "60 kDa heat shock protein, mitochondrial", "refseq_ac": [ { "id": "NP_001233659", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233659", "type": "external" } ], "gene_names_uniprotkb": "Hspd1", "gene_names_refseq": "CPN60; HSP-60; HSP60; Hspd1", "protein_names_uniprotkb": "60 kDa heat shock protein, mitochondrial; 5.6.1.7; 60 kDa chaperonin; Chaperonin 60; Heat shock protein 60; Mitochondrial matrix protein P1", "protein_names_refseq": "60 kDa chaperonin; 60 kDa heat shock protein, mitochondrial; Chaperonin 60; Heat shock protein 60; Mitochondrial matrix protein P1; P1 protein; heat shock 60kDa protein 1 (chaperonin); heat shock protein 1 (chaperonin)", "tax_id": 10029, "disease": "", "pathway": " (cge:100689473)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: M22383.1, IACG01056708.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M22383.1. On or before Aug 30, 2024 this sequence version replaced XP_003504389.1, XP_027252702.1., [RefSeq]; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0001530 lipopolysaccharide binding;GO:0016853 isomerase activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005886 plasma membrane;GO:0030141 secretory granule;GO:0140494 migrasome", "go_biological_process": "GO:0032729 positive regulation of type II interferon production;GO:0050870 positive regulation of T cell activation;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBI2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FBJ8-1", "uniprot_id": [ { "id": "A0A9J7FBJ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FBJ8", "type": "external" } ], "mass": 106164.0, "length": 986, "protein_name": "Lysine-specific histone demethylase 1A", "gene_name": "Kdm1a", "organism": "Hamster", "refseq_name": "lysine-specific histone demethylase 1A isoform X2", "refseq_ac": [ { "id": "XP_027255543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255543", "type": "external" } ], "gene_names_uniprotkb": "Kdm1a", "gene_names_refseq": "Kdm1a", "protein_names_uniprotkb": "Lysine-specific histone demethylase 1A; 1.14.11.65; 1.14.99.66; BRAF35-HDAC complex protein BHC110", "protein_names_refseq": "lysine-specific histone demethylase 1A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770721)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Neuron-specific histone demethylase that demethylates mono- and dimethylated 'Lys-20' of histone H4 (H4K20me1 and H4K20me2), a chromatin repressive mark. This demethylation is crucial for the initiation and elongation of neuronal activity-regulated genes, required for spatial learning and memory. Mediates H3K9me2 demethylation through cooperation with the supervillin protein (SVIL), and this H3K9 demethylase activity is essential for regulating gene expression during neuronal differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.65", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.65", "type": "external" }, { "id": "1.14.99.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0019899 enzyme binding;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045597 positive regulation of cell differentiation;GO:2000179 positive regulation of neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FBJ8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FCQ8-1", "uniprot_id": [ { "id": "A0A9J7FCQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FCQ8", "type": "external" } ], "mass": 16784.0, "length": 153, "protein_name": "Natriuretic peptides A", "gene_name": "Nppa", "organism": "Hamster", "refseq_name": "natriuretic peptides A", "refseq_ac": [ { "id": "XP_027253980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253980", "type": "external" } ], "gene_names_uniprotkb": "Nppa", "gene_names_refseq": "Nppa", "protein_names_uniprotkb": "Natriuretic peptides A; Atrial natriuretic factor prohormone; Atrial natriuretic peptide prohormone; Atriopeptigen; Cardiodilatin; preproCDD-ANF", "protein_names_refseq": "natriuretic peptides A", "tax_id": 10029, "disease": "", "pathway": " (cge:100774350)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney., [UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption., [UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption., [UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0051427 hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0006182 cGMP biosynthetic process;GO:0007218 neuropeptide signaling pathway;GO:0097746 blood vessel diameter maintenance;GO:0003085 negative regulation of systemic arterial blood pressure;GO:0007168 receptor guanylyl cyclase signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FCQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FE54-1", "uniprot_id": [ { "id": "A0A9J7FE54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FE54", "type": "external" } ], "mass": 55307.0, "length": 488, "protein_name": "Histone deacetylase 2", "gene_name": "Hdac2", "organism": "Hamster", "refseq_name": "histone deacetylase 2 isoform X1", "refseq_ac": [ { "id": "XP_007642219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642219", "type": "external" } ], "gene_names_uniprotkb": "Hdac2", "gene_names_refseq": "Hdac2", "protein_names_uniprotkb": "Histone deacetylase 2; 3.5.1.98; HD2", "protein_names_refseq": "histone deacetylase 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764557)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 331 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613969.1) and transcript sequence (IACG01092186.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:0140297 DNA-binding transcription factor binding;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016581 NuRD complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FE54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FF49-1", "uniprot_id": [ { "id": "A0A9J7FF49_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FF49", "type": "external" } ], "mass": 127571.0, "length": 1174, "protein_name": "Polyamine-transporting ATPase 13A2", "gene_name": "Atp13a2", "organism": "Hamster", "refseq_name": "polyamine-transporting ATPase 13A2 isoform X2", "refseq_ac": [ { "id": "XP_027255692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255692", "type": "external" } ], "gene_names_uniprotkb": "Atp13a2", "gene_names_refseq": "Atp13a2", "protein_names_uniprotkb": "Polyamine-transporting ATPase 13A2", "protein_names_refseq": "polyamine-transporting ATPase 13A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770673)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATPase which acts as a lysosomal polyamine exporter with high affinity for spermine. Also stimulates cellular uptake of polyamines and protects against polyamine toxicity. Plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity. Contributes to cellular zinc homeostasis. Confers cellular protection against Mn(2+) and Zn(2+) toxicity and mitochondrial stress. Required for proper lysosomal and mitochondrial maintenance. Regulates the autophagy-lysosome pathway through the control of SYT11 expression at both transcriptional and post-translational levels. Facilitates recruitment of deacetylase HDAC6 to lysosomes to deacetylate CTTN, leading to actin polymerization, promotion of autophagosome-lysosome fusion and completion of autophagy. Promotes secretion of exosomes as well as secretion of SCNA via exosomes. Plays a role in lipid homeostasis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity;GO:0015662 P-type ion transporter activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0043025 neuronal cell body;GO:0005765 lysosomal membrane;GO:0043005 neuron projection;GO:0032585 multivesicular body membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0034599 cellular response to oxidative stress;GO:0006882 intracellular zinc ion homeostasis;GO:0010821 regulation of mitochondrion organization;GO:0016243 regulation of autophagosome size", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FF49-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FFD8-1", "uniprot_id": [ { "id": "A0A9J7FFD8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FFD8", "type": "external" } ], "mass": 84974.0, "length": 754, "protein_name": "tRNA (cytosine(34)-C(5))-methyltransferase", "gene_name": "Nsun2", "organism": "Hamster", "refseq_name": "RNA cytosine C(5)-methyltransferase NSUN2 isoform X2", "refseq_ac": [ { "id": "XP_027255922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255922", "type": "external" } ], "gene_names_uniprotkb": "Nsun2", "gene_names_refseq": "Nsun2", "protein_names_uniprotkb": "tRNA (cytosine(34)-C(5))-methyltransferase; 2.1.1.203; NOL1/NOP2/Sun domain family member 2; mRNA cytosine C(5)-methyltransferase; tRNA cytosine C(5)-methyltransferase", "protein_names_refseq": "RNA cytosine C(5)-methyltransferase NSUN2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760286)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.203", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.203", "type": "external" } ], "go_molecular_function": "GO:0016428 tRNA (cytidine-5-)-methyltransferase activity;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FFD8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FHE6-1", "uniprot_id": [ { "id": "A0A9J7FHE6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FHE6", "type": "external" } ], "mass": 60849.0, "length": 534, "protein_name": "Beta-hexosaminidase", "gene_name": "LOC100766960", "organism": "Hamster", "refseq_name": "beta-hexosaminidase subunit beta isoform X2", "refseq_ac": [ { "id": "XP_027257469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257469", "type": "external" } ], "gene_names_uniprotkb": "LOC100766960", "gene_names_refseq": "LOC100766960", "protein_names_uniprotkb": "Beta-hexosaminidase; 3.2.1.52", "protein_names_refseq": "beta-hexosaminidase subunit beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766960)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.52", "type": "external" } ], "go_molecular_function": "GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005764 lysosome;GO:0060473 cortical granule", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0005975 carbohydrate metabolic process;GO:0030203 glycosaminoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FHE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FL59-1", "uniprot_id": [ { "id": "A0A9J7FL59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FL59", "type": "external" } ], "mass": 103009.0, "length": 923, "protein_name": "Neuropilin", "gene_name": "Nrp1", "organism": "Hamster", "refseq_name": "neuropilin-1 isoform X1", "refseq_ac": [ { "id": "XP_027260563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260563", "type": "external" } ], "gene_names_uniprotkb": "Nrp1", "gene_names_refseq": "Nrp1", "protein_names_uniprotkb": "Neuropilin", "protein_names_refseq": "neuropilin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763324)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0046872 metal ion binding;GO:0017154 semaphorin receptor activity;GO:0005021 vascular endothelial growth factor receptor activity;GO:0038085 vascular endothelial growth factor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030424 axon;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0001570 vasculogenesis;GO:0010595 positive regulation of endothelial cell migration;GO:0009611 response to wounding;GO:0001755 neural crest cell migration;GO:0048010 vascular endothelial growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FL59-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI14-1", "uniprot_id": [ { "id": "A0A9J7FI14_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI14", "type": "external" } ], "mass": 62279.0, "length": 552, "protein_name": "5'-AMP-activated protein kinase catalytic subunit alpha-2", "gene_name": "Prkaa2", "organism": "Hamster", "refseq_name": "5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2", "refseq_ac": [ { "id": "XP_027258139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258139", "type": "external" } ], "gene_names_uniprotkb": "Prkaa2", "gene_names_refseq": "Prkaa2", "protein_names_uniprotkb": "5'-AMP-activated protein kinase catalytic subunit alpha-2; 2.7.11.1; 2.7.11.31; Acetyl-CoA carboxylase kinase; Hydroxymethylglutaryl-CoA reductase kinase", "protein_names_refseq": "5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767909)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004679 AMP-activated protein kinase activity;GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0035556 intracellular signal transduction;GO:0071333 cellular response to glucose stimulus;GO:0006633 fatty acid biosynthetic process;GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI19-1", "uniprot_id": [ { "id": "A0A9J7FI19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI19", "type": "external" } ], "mass": 69472.0, "length": 608, "protein_name": "DNA repair protein Ku70", "gene_name": "Xrcc6", "organism": "Hamster", "refseq_name": "X-ray repair cross-complementing protein 6", "refseq_ac": [ { "id": "XP_027259903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259903", "type": "external" } ], "gene_names_uniprotkb": "Xrcc6", "gene_names_refseq": "Xrcc6", "protein_names_uniprotkb": "DNA repair protein Ku70; 4.2.99.18; 5'-deoxyribose-5-phosphate lyase Ku70; 5.6.2.4; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; DNA repair protein XRCC6; X-ray repair cross-complementing protein 6", "protein_names_refseq": "X-ray repair cross-complementing protein 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100770214)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "1.14.11.51", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.51", "type": "external" }, { "id": "1.14.11.33", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.33", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.-", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0042162 telomeric DNA binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0000723 telomere maintenance;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FI80-1", "uniprot_id": [ { "id": "A0A9J7FI80_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FI80", "type": "external" } ], "mass": 60164.0, "length": 527, "protein_name": "Beta-hexosaminidase", "gene_name": "LOC100756663", "organism": "Hamster", "refseq_name": "beta-hexosaminidase subunit beta isoform X2", "refseq_ac": [ { "id": "XP_027257467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257467", "type": "external" } ], "gene_names_uniprotkb": "LOC100756663", "gene_names_refseq": "LOC100756663", "protein_names_uniprotkb": "Beta-hexosaminidase; 3.2.1.52", "protein_names_refseq": "beta-hexosaminidase subunit beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756663)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.52", "type": "external" } ], "go_molecular_function": "GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005764 lysosome;GO:0060473 cortical granule", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0005975 carbohydrate metabolic process;GO:0030203 glycosaminoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FI80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJP4-1", "uniprot_id": [ { "id": "A0A9J7FJP4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJP4", "type": "external" } ], "mass": 344040.0, "length": 3118, "protein_name": "Laminin subunit alpha-2", "gene_name": "LOC100771923", "organism": "Hamster", "refseq_name": "laminin subunit alpha-2 isoform X3", "refseq_ac": [ { "id": "XP_027258672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258672", "type": "external" } ], "gene_names_uniprotkb": "LOC100771923", "gene_names_refseq": "LOC100771923", "protein_names_uniprotkb": "Laminin subunit alpha-2; Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain", "protein_names_refseq": "laminin subunit alpha-2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100771923)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0030054 cell junction;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0030155 regulation of cell adhesion;GO:0030334 regulation of cell migration;GO:0045995 regulation of embryonic development;GO:0009887 animal organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJP4-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FJ23-1", "uniprot_id": [ { "id": "A0A9J7FJ23_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FJ23", "type": "external" } ], "mass": 184090.0, "length": 1604, "protein_name": "Myosin-IIIa", "gene_name": "LOC100757928", "organism": "Hamster", "refseq_name": "myosin-IIIa isoform X3", "refseq_ac": [ { "id": "XP_027261146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261146", "type": "external" } ], "gene_names_uniprotkb": "LOC100757928", "gene_names_refseq": "LOC100757928", "protein_names_uniprotkb": "Myosin-IIIa; 2.7.11.1", "protein_names_refseq": "myosin-IIIa isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757928)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", 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"url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001917 photoreceptor inner segment;GO:0032433 filopodium tip;GO:0032426 stereocilium tip;GO:0016459 myosin complex", "go_biological_process": "GO:0030832 regulation of actin filament length;GO:0007601 visual perception;GO:0007605 sensory perception of sound;GO:0051491 positive regulation of filopodium assembly;GO:0060088 auditory receptor cell stereocilium organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FJ23-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FKH8-1", "uniprot_id": [ { "id": "A0A9J7FKH8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FKH8", "type": "external" } ], "mass": 41406.0, "length": 371, "protein_name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "gene_name": "Coq3", "organism": "Hamster", "refseq_name": "ubiquinone biosynthesis O-methyltransferase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_027259253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259253", "type": "external" } ], "gene_names_uniprotkb": "Coq3; COQ3", "gene_names_refseq": "Coq3", "protein_names_uniprotkb": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial; 2.1.1.-; 2.1.1.114; 2.1.1.64; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone 3-O-methyltransferase; Polyprenyldihydroxybenzoate methyltransferase", "protein_names_refseq": "ubiquinone biosynthesis O-methyltransferase, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763494)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol-10 into ubiquinol-10., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.114", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.114", "type": "external" }, { "id": "2.1.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.64", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0010420 polyprenyldihydroxybenzoate methyltransferase activity;GO:0061542 3-demethylubiquinol 3-O-methyltransferase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FKH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FL07-1", "uniprot_id": [ { "id": "A0A9J7FL07_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FL07", "type": "external" } ], "mass": 71445.0, "length": 626, "protein_name": "Lysine--tRNA ligase", "gene_name": "Kars1", "organism": "Hamster", "refseq_name": "lysine--tRNA ligase isoform X1", "refseq_ac": [ { "id": "XP_027261865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261865", "type": "external" } ], "gene_names_uniprotkb": "Kars1", "gene_names_refseq": "Kars1", "protein_names_uniprotkb": "Lysine--tRNA ligase; 6.1.1.6; Lysyl-tRNA synthetase", "protein_names_refseq": "lysine--tRNA ligase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766627)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.6", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0000049 tRNA binding;GO:0003877 ATP:ADP adenylyltransferase activity;GO:0004824 lysine-tRNA ligase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0015966 diadenosine tetraphosphate biosynthetic process;GO:0002276 basophil activation involved in immune response;GO:0006430 lysyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FL07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FMQ6-1", "uniprot_id": [ { "id": "A0A9J7FMQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FMQ6", "type": "external" } ], "mass": 108088.0, "length": 962, "protein_name": "Phosphodiesterase", "gene_name": "Pde2a", "organism": "Hamster", "refseq_name": "cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X4", "refseq_ac": [ { "id": "XP_027263629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263629", "type": "external" } ], "gene_names_uniprotkb": "Pde2a", "gene_names_refseq": "Pde2a", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100750420)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulates mitochondrial cAMP levels and respiration. Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. Plays a role in cell growth and migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0030553 cGMP binding;GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0009968 negative regulation of signal transduction;GO:0010821 regulation of mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FMQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPD5-1", "uniprot_id": [ { "id": "A0A9J7FPD5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPD5", "type": "external" } ], "mass": 71198.0, "length": 655, "protein_name": "Sphingomyelin phosphodiesterase 3", "gene_name": "Smpd3", "organism": "Hamster", "refseq_name": "sphingomyelin phosphodiesterase 3 isoform X2", "refseq_ac": [ { "id": "XP_027261718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261718", "type": "external" } ], "gene_names_uniprotkb": "Smpd3", "gene_names_refseq": "Smpd3", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase 3; 3.1.4.12; Neutral sphingomyelinase 2; Neutral sphingomyelinase II", "protein_names_refseq": "sphingomyelin phosphodiesterase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755276)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.12", "type": "external" }, { "id": "3.1.4.38", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.38", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004620 phospholipase activity;GO:0004767 sphingomyelin phosphodiesterase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0006684 sphingomyelin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FPH4-1", "uniprot_id": [ { "id": "A0A9J7FPH4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FPH4", "type": "external" } ], "mass": 31365.0, "length": 290, "protein_name": "Enoyl-CoA hydratase, mitochondrial", "gene_name": "Echs1", "organism": "Hamster", "refseq_name": "enoyl-CoA hydratase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_003515014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515014", "type": "external" } ], "gene_names_uniprotkb": "Echs1", "gene_names_refseq": "Echs1", "protein_names_uniprotkb": "Enoyl-CoA hydratase, mitochondrial; 4.2.1.17; 5.3.3.8; Enoyl-CoA hydratase 1; Short-chain enoyl-CoA hydratase", "protein_names_refseq": "enoyl-CoA hydratase, mitochondrial isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754654)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 276 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617176.1) and transcript sequence (JP065964.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003515014.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "4.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.17", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "1.1.1.211", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.211", "type": "external" } ], "go_molecular_function": "GO:0004300 enoyl-CoA hydratase activity;GO:0004165 delta(3)-delta(2)-enoyl-CoA isomerase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FPH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FSC3-1", "uniprot_id": [ { "id": "A0A9J7FSC3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FSC3", "type": "external" } ], "mass": 102130.0, "length": 886, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Nedd4", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase NEDD4 isoform X2", "refseq_ac": [ { "id": "XP_027266983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266983", "type": "external" } ], "gene_names_uniprotkb": "Nedd4", "gene_names_refseq": "Nedd4", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase NEDD4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755507)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019871 sodium channel inhibitor activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043197 dendritic spine;GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005886 plasma membrane", "go_biological_process": "GO:0007528 neuromuscular junction development;GO:0031175 neuron projection development;GO:0031623 receptor internalization;GO:0048814 regulation of dendrite morphogenesis;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FSC3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FUH6-1", "uniprot_id": [ { "id": "A0A9J7FUH6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FUH6", "type": "external" } ], "mass": 285377.0, "length": 2571, "protein_name": "DNA polymerase theta", "gene_name": "Polq", "organism": "Hamster", "refseq_name": "DNA polymerase theta isoform X1", "refseq_ac": [ { "id": "XP_027268515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268515", "type": "external" } ], "gene_names_uniprotkb": "Polq", "gene_names_refseq": "Polq", "protein_names_uniprotkb": "DNA polymerase theta; 2.7.7.49; 2.7.7.7; 3.6.4.12; DNA polymerase eta", "protein_names_refseq": "DNA polymerase theta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764158)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003964 RNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0097681 double-strand break repair via alternative nonhomologous end joining;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FUH6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWV1-1", "uniprot_id": [ { "id": "A0A9J7FWV1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWV1", "type": "external" } ], "mass": 80365.0, "length": 712, "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "Rnf168", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF168", "refseq_ac": [ { "id": "XP_003495446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495446", "type": "external" } ], "gene_names_uniprotkb": "Rnf168; RNF168", "gene_names_refseq": "Rnf168", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF168; 2.3.2.27; RING finger protein 168; RING-type E3 ubiquitin transferase RNF168", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF168", "tax_id": 10029, "disease": "", "pathway": " (cge:100753166)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613591.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003495446.2. COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding;GO:0043130 ubiquitin binding;GO:0031491 nucleosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0006302 double-strand break repair;GO:0010212 response to ionizing radiation;GO:0045739 positive regulation of DNA repair;GO:0016567 protein ubiquitination;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FWW4-1", "uniprot_id": [ { "id": "A0A9J7FWW4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FWW4", "type": "external" } ], "mass": 22834.0, "length": 206, "protein_name": "U8 snoRNA-decapping enzyme", "gene_name": "LOC100769259", "organism": "Hamster", "refseq_name": "U8 snoRNA-decapping enzyme", "refseq_ac": [ { "id": "XP_003497692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497692", "type": "external" } ], "gene_names_uniprotkb": "LOC100769259", "gene_names_refseq": "LOC100769259", "protein_names_uniprotkb": "U8 snoRNA-decapping enzyme; 3.6.1.62; 3.6.1.64; IDP phosphatase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; m7GpppN-mRNA hydrolase", "protein_names_refseq": "U8 snoRNA-decapping enzyme", "tax_id": 10029, "disease": "", "pathway": " (cge:100769259)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.6.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.76", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" }, { "id": "3.6.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.77", "type": "external" }, { "id": "3.6.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.17", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0030515 snoRNA binding;GO:1990174 phosphodiesterase decapping endonuclease activity;GO:1990003 IDP phosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009117 nucleotide metabolic process;GO:0006402 mRNA catabolic process;GO:0016077 sno(s)RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FWW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FX84-1", "uniprot_id": [ { "id": "A0A9J7FX84_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FX84", "type": "external" } ], "mass": 152667.0, "length": 1397, "protein_name": "Macrophage-stimulating protein receptor", "gene_name": "Mst1r", "organism": "Hamster", "refseq_name": "macrophage-stimulating protein receptor isoform X1", "refseq_ac": [ { "id": "XP_027270309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270309", "type": "external" } ], "gene_names_uniprotkb": "Mst1r", "gene_names_refseq": "Mst1r", "protein_names_uniprotkb": "Macrophage-stimulating protein receptor; 2.7.10.1; p185-Ron", "protein_names_refseq": "macrophage-stimulating protein receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758551)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0006909 phagocytosis;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FX84-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FXN0-1", "uniprot_id": [ { "id": "A0A9J7FXN0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FXN0", "type": "external" } ], "mass": 97565.0, "length": 876, "protein_name": "Protein PML", "gene_name": "Pml", "organism": "Hamster", "refseq_name": "protein PML isoform X1", "refseq_ac": [ { "id": "XP_027270719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270719", "type": "external" } ], "gene_names_uniprotkb": "Pml", "gene_names_refseq": "Pml", "protein_names_uniprotkb": "Protein PML", "protein_names_refseq": "protein PML isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757598)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005789 endoplasmic reticulum membrane;GO:0031901 early endosome membrane;GO:0016363 nuclear matrix;GO:0016605 PML body", "go_biological_process": "GO:0044790 suppression of viral release by host;GO:0030578 PML body organization;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FXN0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G270-1", "uniprot_id": [ { "id": "A0A9J7G270_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G270", "type": "external" } ], "mass": 349858.0, "length": 3061, "protein_name": "Serine-protein kinase ATM", "gene_name": "LOC100754226", "organism": "Hamster", "refseq_name": "serine-protein kinase ATM isoform X6", "refseq_ac": [ { "id": "XP_027270889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270889", "type": "external" } ], "gene_names_uniprotkb": "LOC100754226", "gene_names_refseq": "LOC100754226", "protein_names_uniprotkb": "Serine-protein kinase ATM; 2.7.11.1", "protein_names_refseq": "serine-protein kinase ATM isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100754226)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005782 peroxisomal matrix;GO:0005813 centrosome;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0010506 regulation of autophagy;GO:0043065 positive regulation of apoptotic process;GO:0010212 response to ionizing radiation;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G270-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYV6-1", "uniprot_id": [ { "id": "A0A9J7FYV6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYV6", "type": "external" } ], "mass": 116291.0, "length": 1037, "protein_name": "Huntingtin-interacting protein 1", "gene_name": "Hip1", "organism": "Hamster", "refseq_name": "huntingtin-interacting protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003500976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500976", "type": "external" } ], "gene_names_uniprotkb": "Hip1", "gene_names_refseq": "Hip1", "protein_names_uniprotkb": "Huntingtin-interacting protein 1; Huntingtin-interacting protein I", "protein_names_refseq": "huntingtin-interacting protein 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757209)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613822.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Regulates presynaptic nerve terminal activity. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0051015 actin filament binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0035615 clathrin adaptor activity;GO:0032051 clathrin light chain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0030665 clathrin-coated vesicle membrane;GO:0030864 cortical actin cytoskeleton;GO:0098793 presynapse", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030154 cell differentiation;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYV6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FYQ7-1", "uniprot_id": [ { "id": "A0A9J7FYQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FYQ7", "type": "external" } ], "mass": 32667.0, "length": 296, "protein_name": "Carbonyl reductase (NADPH)", "gene_name": "LOC100753466", "organism": "Hamster", "refseq_name": "carbonyl reductase [NADPH] 1", "refseq_ac": [ { "id": "XP_027271432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271432", "type": "external" } ], "gene_names_uniprotkb": "LOC100753466", "gene_names_refseq": "LOC100753466", "protein_names_uniprotkb": "Carbonyl reductase (NADPH); 1.1.1.184", "protein_names_refseq": "carbonyl reductase [NADPH] 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753466)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "1.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.2", "type": "external" }, { "id": "1.1.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.19", "type": "external" }, { "id": "1.1.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.20", "type": "external" }, { "id": "1.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.372", "type": "external" }, { "id": "1.1.1.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.54", "type": "external" }, { "id": "1.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity;GO:0050221 prostaglandin E2 9-reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FYQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ00-1", "uniprot_id": [ { "id": "A0A9J7FZ00_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ00", "type": "external" } ], "mass": 15365.0, "length": 137, "protein_name": "Phospholipase A2", "gene_name": "LOC100765177", "organism": "Hamster", "refseq_name": "phospholipase A2", "refseq_ac": [ { "id": "XP_003510846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510846", "type": "external" } ], "gene_names_uniprotkb": "LOC100765177", "gene_names_refseq": "LOC100765177", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765177)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614968.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZ00-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ10-1", "uniprot_id": [ { "id": "A0A9J7FZ10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ10", "type": "external" } ], "mass": 13633.0, "length": 122, "protein_name": "Phospholipase A2", "gene_name": "LOC113835677", "organism": "Hamster", "refseq_name": "phospholipase A2", "refseq_ac": [ { "id": "XP_027271890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271890", "type": "external" } ], "gene_names_uniprotkb": "LOC113835677", "gene_names_refseq": "LOC113835677", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:113835677)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZ10-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7FZ67-1", "uniprot_id": [ { "id": "A0A9J7FZ67_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7FZ67", "type": "external" } ], "mass": 15203.0, "length": 131, "protein_name": "Phospholipase A2", "gene_name": "LOC100766341", "organism": "Hamster", "refseq_name": "phospholipase A2", "refseq_ac": [ { "id": "XP_003510849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510849", "type": "external" } ], "gene_names_uniprotkb": "LOC100766341", "gene_names_refseq": "LOC100766341", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766341)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614968.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7FZ67-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0I4-1", "uniprot_id": [ { "id": "A0A9J7G0I4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0I4", "type": "external" } ], "mass": 106484.0, "length": 960, "protein_name": "Lon protease homolog, mitochondrial", "gene_name": "Lonp1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: lon protease homolog, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027272634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272634", "type": "external" } ], "gene_names_uniprotkb": "Lonp1; LONP1", "gene_names_refseq": "Lonp1", "protein_names_uniprotkb": "Lon protease homolog, mitochondrial; 3.4.21.53; LONP; Lon protease-like protein; Mitochondrial ATP-dependent protease Lon; Serine protease 15", "protein_names_refseq": "LOW QUALITY PROTEIN: lon protease homolog, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771385)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043565 sequence-specific DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0007005 mitochondrion organization;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0051131 chaperone-mediated protein complex assembly;GO:0070407 oxidation-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0I4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G0L6-1", "uniprot_id": [ { "id": "A0A9J7G0L6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G0L6", "type": "external" } ], "mass": 30648.0, "length": 277, "protein_name": "Carbonyl reductase (NADPH)", "gene_name": "LOC113835641", "organism": "Hamster", "refseq_name": "carbonyl reductase [NADPH] 1-like", "refseq_ac": [ { "id": "XP_027271430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271430", "type": "external" } ], "gene_names_uniprotkb": "LOC113835641", "gene_names_refseq": "LOC113835641", "protein_names_uniprotkb": "Carbonyl reductase (NADPH); 1.1.1.184", "protein_names_refseq": "carbonyl reductase [NADPH] 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113835641)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "1.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.2", "type": "external" }, { "id": "1.1.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.19", "type": "external" }, { "id": "1.1.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.20", "type": "external" }, { "id": "1.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.372", "type": "external" }, { "id": "1.1.1.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.54", "type": "external" }, { "id": "1.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity;GO:0050221 prostaglandin E2 9-reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G0L6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1R4-1", "uniprot_id": [ { "id": "A0A9J7G1R4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1R4", "type": "external" } ], "mass": 35052.0, "length": 320, "protein_name": "11-beta-hydroxysteroid dehydrogenase 1", "gene_name": "Hsd11b1", "organism": "Hamster", "refseq_name": "corticosteroid 11-beta-dehydrogenase isozyme 1", "refseq_ac": [ { "id": "XP_003498616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498616", "type": "external" } ], "gene_names_uniprotkb": "Hsd11b1", "gene_names_refseq": "Hsd11b1", "protein_names_uniprotkb": "11-beta-hydroxysteroid dehydrogenase 1; 1.1.1.146; 1.1.1.201; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1", "protein_names_refseq": "corticosteroid 11-beta-dehydrogenase isozyme 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762502)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613696.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003498616.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.146", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.146", "type": "external" }, { "id": "1.1.1.201", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.201", "type": "external" } ], "go_molecular_function": "GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0005496 steroid binding;GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006706 steroid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1R4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G1X3-1", "uniprot_id": [ { "id": "A0A9J7G1X3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G1X3", "type": "external" } ], "mass": 31763.0, "length": 277, "protein_name": "Flavin-containing monooxygenase", "gene_name": "LOC100773480", "organism": "Hamster", "refseq_name": "flavin-containing monooxygenase 5", "refseq_ac": [ { "id": "XP_007653045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653045", "type": "external" } ], "gene_names_uniprotkb": "LOC100773480", "gene_names_refseq": "LOC100773480", "protein_names_uniprotkb": "Flavin-containing monooxygenase; 1.-.-.-", "protein_names_refseq": "flavin-containing monooxygenase 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100773480)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616972.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects., [UniProtKB, UniProtKB]; Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.1", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.14.13.148", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.148", "type": "external" }, { "id": "1.14.13.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.8", "type": "external" }, { "id": "1.14.13.32", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.32", "type": "external" }, { "id": "1.6.99.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.99.1", "type": "external" }, { "id": "1.14.13.225", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.225", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity;GO:0034899 trimethylamine monooxygenase activity;GO:0050661 NADP binding;GO:0004499 N,N-dimethylaniline monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G1X3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G368-1", "uniprot_id": [ { "id": "A0A9J7G368_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G368", "type": "external" } ], "mass": 63157.0, "length": 561, "protein_name": "Serine/threonine-protein kinase STK11", "gene_name": "Stk11", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase STK11 isoform X4", "refseq_ac": [ { "id": "XP_027275195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275195", "type": "external" } ], "gene_names_uniprotkb": "Stk11", "gene_names_refseq": "Stk11", "protein_names_uniprotkb": "Serine/threonine-protein kinase STK11; 2.7.11.1; Liver kinase B1 homolog", "protein_names_refseq": "serine/threonine-protein kinase STK11 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100765813)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275195.1. COMPLETENESS: full length., [RefSeq]; Has a role in spermiogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007283 spermatogenesis;GO:0035556 intracellular signal transduction;GO:0006915 apoptotic process;GO:0006974 DNA damage response;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G368-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2G6-1", "uniprot_id": [ { "id": "A0A9J7G2G6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2G6", "type": "external" } ], "mass": 55408.0, "length": 500, "protein_name": "nucleoside diphosphate phosphatase", "gene_name": "Entpd5", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 5", "refseq_ac": [ { "id": "XP_007643874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643874", "type": "external" } ], "gene_names_uniprotkb": "Entpd5", "gene_names_refseq": "Entpd5", "protein_names_uniprotkb": "nucleoside diphosphate phosphatase; 3.6.1.6; Guanosine-diphosphatase ENTPD5; Uridine-diphosphatase ENTPD5", "protein_names_refseq": "LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100751454)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614123.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007643874.1. COMPLETENESS: full length., [RefSeq]; Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP. In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0017110 nucleoside diphosphate phosphatase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2G6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G2T1-1", "uniprot_id": [ { "id": "A0A9J7G2T1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G2T1", "type": "external" } ], "mass": 150025.0, "length": 1388, "protein_name": "ATP-dependent RNA helicase A", "gene_name": "Dhx9", "organism": "Hamster", "refseq_name": "ATP-dependent RNA helicase A isoform X2", "refseq_ac": [ { "id": "XP_027273161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273161", "type": "external" } ], "gene_names_uniprotkb": "Dhx9", "gene_names_refseq": "Dhx9", "protein_names_uniprotkb": "ATP-dependent RNA helicase A; 3.6.4.13; DEAH box protein 9; Nuclear DNA helicase II", "protein_names_refseq": "ATP-dependent RNA helicase A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765632)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0001069 regulatory region RNA binding;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005813 centrosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006417 regulation of translation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0008380 RNA splicing;GO:0031047 regulatory ncRNA-mediated gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G2T1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G659-1", "uniprot_id": [ { "id": "A0A9J7G659_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G659", "type": "external" } ], "mass": 138916.0, "length": 1252, "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "Rtel1", "organism": "Hamster", "refseq_name": "regulator of telomere elongation helicase 1 isoform X1", "refseq_ac": [ { "id": "XP_007641953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641953", "type": "external" } ], "gene_names_uniprotkb": "Rtel1; RTEL1", "gene_names_refseq": "Rtel1", "protein_names_uniprotkb": "Regulator of telomere elongation helicase 1; 5.6.2.-", "protein_names_refseq": "regulator of telomere elongation helicase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762036)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613943.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A probable ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0070182 DNA polymerase binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0090657 telomeric loop disassembly;GO:1904430 negative regulation of t-circle formation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G659-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4I1-1", "uniprot_id": [ { "id": "A0A9J7G4I1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4I1", "type": "external" } ], "mass": 169781.0, "length": 1511, "protein_name": "Bifunctional glutamate/proline--tRNA ligase", "gene_name": "Eprs1", "organism": "Hamster", "refseq_name": "bifunctional glutamate/proline--tRNA ligase isoform X1", "refseq_ac": [ { "id": "XP_016830342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830342", "type": "external" } ], "gene_names_uniprotkb": "Eprs1", "gene_names_refseq": "Eprs1", "protein_names_uniprotkb": "Bifunctional glutamate/proline--tRNA ligase; 6.1.1.15; 6.1.1.17; Bifunctional aminoacyl-tRNA synthetase", "protein_names_refseq": "bifunctional glutamate/proline--tRNA ligase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774338)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 349 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613581.1) and transcript sequence (IACG01094299.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016830342.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.15", "type": "external" }, { "id": "6.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.17", "type": "external" }, { "id": "6.1.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.24", "type": "external" } ], "go_molecular_function": "GO:0004827 proline-tRNA ligase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0017101 aminoacyl-tRNA synthetase multienzyme complex;GO:1990904 ribonucleoprotein complex;GO:0097452 GAIT complex", "go_biological_process": "GO:0006433 prolyl-tRNA aminoacylation;GO:0032869 cellular response to insulin stimulus;GO:0017148 negative regulation of translation;GO:0071346 cellular response to type II interferon;GO:0006424 glutamyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4I1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G4U8-1", "uniprot_id": [ { "id": "A0A9J7G4U8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G4U8", "type": "external" } ], "mass": 68108.0, "length": 624, "protein_name": "Vesicular glutamate transporter 1", "gene_name": "Slc17a7", "organism": "Hamster", "refseq_name": "vesicular glutamate transporter 1 isoform X2", "refseq_ac": [ { "id": "XP_027276466", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276466", "type": "external" } ], "gene_names_uniprotkb": "Slc17a7", "gene_names_refseq": "Slc17a7", "protein_names_uniprotkb": "Vesicular glutamate transporter 1; Solute carrier family 17 member 7", "protein_names_refseq": "vesicular glutamate transporter 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756172)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027276466.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015293 symporter activity;GO:0015297 antiporter activity;GO:0005254 chloride channel activity;GO:0140788 L-glutamate uniporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0030672 synaptic vesicle membrane;GO:0034707 chloride channel complex;GO:0060076 excitatory synapse", "go_biological_process": "GO:0050803 regulation of synapse structure or activity;GO:0035249 synaptic transmission, glutamatergic;GO:0006814 sodium ion transport;GO:0006817 phosphate ion transport;GO:0098700 neurotransmitter loading into synaptic vesicle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G4U8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G5M3-1", "uniprot_id": [ { "id": "A0A9J7G5M3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G5M3", "type": "external" } ], "mass": 21757.0, "length": 198, "protein_name": "Inosine triphosphate pyrophosphatase", "gene_name": "Itpa", "organism": "Hamster", "refseq_name": "inosine triphosphate pyrophosphatase isoform X2", "refseq_ac": [ { "id": "XP_027277579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277579", "type": "external" } ], "gene_names_uniprotkb": "Itpa; ITPA", "gene_names_refseq": "Itpa", "protein_names_uniprotkb": "Inosine triphosphate pyrophosphatase; 3.6.1.66; ITPase; Inosine triphosphatase; NTPase; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; XTP/dITP diphosphatase", "protein_names_refseq": "inosine triphosphate pyrophosphatase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768122)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions., [UniProtKB, HAMAP]; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.66", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.66", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0035870 dITP diphosphatase activity;GO:0036220 ITP diphosphatase activity;GO:0036222 XTP diphosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009117 nucleotide metabolic process;GO:0009204 deoxyribonucleoside triphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G5M3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6M1-1", "uniprot_id": [ { "id": "A0A9J7G6M1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6M1", "type": "external" } ], "mass": 111261.0, "length": 1003, "protein_name": "Cardiolipin synthase (CMP-forming)", "gene_name": "Mcm8", "organism": "Hamster", "refseq_name": "DNA helicase MCM8 isoform X1", "refseq_ac": [ { "id": "XP_027277501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277501", "type": "external" } ], "gene_names_uniprotkb": "Mcm8", "gene_names_refseq": "Mcm8", "protein_names_uniprotkb": "Cardiolipin synthase (CMP-forming); 2.7.8.41; 5.6.2.4; DNA 3'-5' helicase MCM8; DNA helicase MCM8; Minichromosome maintenance 8", "protein_names_refseq": "DNA helicase MCM8 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100772692)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0043337 cardiolipin synthase (CMP-forming);GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003697 single-stranded DNA binding;GO:0017116 single-stranded DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane;GO:0005694 chromosome;GO:0097362 MCM8-MCM9 complex", "go_biological_process": "GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination;GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6M1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G6S5-1", "uniprot_id": [ { "id": "A0A9J7G6S5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G6S5", "type": "external" } ], "mass": 212803.0, "length": 1863, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Trpm7", "organism": "Hamster", "refseq_name": "transient receptor potential cation channel subfamily M member 7 isoform X4", "refseq_ac": [ { "id": "XP_027277719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277719", "type": "external" } ], "gene_names_uniprotkb": "Trpm7", "gene_names_refseq": "Trpm7", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "transient receptor potential cation channel subfamily M member 7 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100752689)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005262 calcium channel activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane", "go_biological_process": "GO:0051262 protein tetramerization;GO:0055080 monoatomic cation homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G6S5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K378-1", "uniprot_id": [ { "id": "A0A9J7K378_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K378", "type": "external" } ], "mass": 100390.0, "length": 899, "protein_name": "receptor protein-tyrosine kinase", "gene_name": "Musk", "organism": "Hamster", "refseq_name": "muscle, skeletal receptor tyrosine-protein kinase isoform X1", "refseq_ac": [ { "id": "XP_035295761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295761", "type": "external" } ], "gene_names_uniprotkb": "Musk", "gene_names_refseq": "Musk", "protein_names_uniprotkb": "receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "muscle, skeletal receptor tyrosine-protein kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756456)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0017147 Wnt-protein binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0031594 neuromuscular junction;GO:0043235 receptor complex;GO:0045211 postsynaptic membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007528 neuromuscular junction development;GO:0030154 cell differentiation;GO:0043113 receptor clustering;GO:0010604 positive regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K378-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2S5-1", "uniprot_id": [ { "id": "A0A9J7K2S5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2S5", "type": "external" } ], "mass": 105169.0, "length": 926, "protein_name": "Peripheral plasma membrane protein CASK", "gene_name": "Cask", "organism": "Hamster", "refseq_name": "peripheral plasma membrane protein CASK isoform X1", "refseq_ac": [ { "id": "XP_016829772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829772", "type": "external" } ], "gene_names_uniprotkb": "Cask", "gene_names_refseq": "Cask", "protein_names_uniprotkb": "Peripheral plasma membrane protein CASK; 2.7.11.1; Calcium/calmodulin-dependent serine protein kinase", "protein_names_refseq": "peripheral plasma membrane protein CASK isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764902)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 213 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613590.1) and transcript sequence (IACG01034372.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016323 basolateral plasma membrane;GO:0030054 cell junction;GO:0005886 plasma membrane", "go_biological_process": "GO:0051050 positive regulation of transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2S5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVH5-1", "uniprot_id": [ { "id": "A0A9J7JVH5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVH5", "type": "external" } ], "mass": 54529.0, "length": 494, "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "Rnf25", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF25 isoform X1", "refseq_ac": [ { "id": "XP_035296928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296928", "type": "external" } ], "gene_names_uniprotkb": "Rnf25", "gene_names_refseq": "Rnf25", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF25; 2.3.2.27; RING finger protein 25; RING finger protein AO7", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF25 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771315)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that plays a key role in the RNF14-RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes. Catalyzes ubiquitination of RPS27A in response to ribosome collisions, promoting activation of RNF14. RNF25 catalyzes ubiquitination of other ribosomal proteins on stalled ribosomes, such as RPL0, RPL1, RPL12, RPS13 and RPS17. Also involved in ubiquitination and degradation of stalled ETF1/eRF1. Independently of its function in the response to stalled ribosomes, mediates ubiquitination and subsequent proteasomal degradation of NKD2. May also stimulate transcription mediated by NF-kappa-B via its interaction with RELA/p65., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051059 NF-kappaB binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0022626 cytosolic ribosome;GO:0005737 cytoplasm", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0085020 protein K6-linked ubiquitination;GO:0160127 protein-RNA covalent cross-linking repair;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JY89-1", "uniprot_id": [ { "id": "A0A9J7JY89_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JY89", "type": "external" } ], "mass": 89427.0, "length": 809, "protein_name": "Striatin", "gene_name": "Strn", "organism": "Hamster", "refseq_name": "striatin isoform X2", "refseq_ac": [ { "id": "XP_027281860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281860", "type": "external" } ], "gene_names_uniprotkb": "Strn", "gene_names_refseq": "Strn", "protein_names_uniprotkb": "Striatin", "protein_names_refseq": "striatin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766324)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0044877 protein-containing complex binding;GO:0051721 protein phosphatase 2A binding;GO:0030331 nuclear estrogen receptor binding;GO:0070016 armadillo repeat domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005923 bicellular tight junction;GO:0016020 membrane;GO:0043197 dendritic spine;GO:0090443 FAR/SIN/STRIPAK complex", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JY89-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXK3-1", "uniprot_id": [ { "id": "A0A9J7JXK3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXK3", "type": "external" } ], "mass": 36690.0, "length": 334, "protein_name": "18S rRNA aminocarboxypropyltransferase", "gene_name": "Tsr3", "organism": "Hamster", "refseq_name": "18S rRNA aminocarboxypropyltransferase isoform X3", "refseq_ac": [ { "id": "XP_027280842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280842", "type": "external" } ], "gene_names_uniprotkb": "Tsr3", "gene_names_refseq": "Tsr3", "protein_names_uniprotkb": "18S rRNA aminocarboxypropyltransferase; 2.5.1.157", "protein_names_refseq": "18S rRNA aminocarboxypropyltransferase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100751647)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.157", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.157", "type": "external" } ], "go_molecular_function": "GO:1904047 S-adenosyl-L-methionine binding;GO:0106388 rRNA small subunit aminocarboxypropyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1H5-1", "uniprot_id": [ { "id": "A0A9J7K1H5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1H5", "type": "external" } ], "mass": 59066.0, "length": 528, "protein_name": "Serine--tRNA ligase, mitochondrial", "gene_name": "Sars2", "organism": "Hamster", "refseq_name": "serine--tRNA ligase, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_035304979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304979", "type": "external" } ], "gene_names_uniprotkb": "Sars2", "gene_names_refseq": "Sars2", "protein_names_uniprotkb": "Serine--tRNA ligase, mitochondrial; 6.1.1.11; SerRSmt; Seryl-tRNA synthetase; Seryl-tRNA(Ser/Sec) synthetase", "protein_names_refseq": "serine--tRNA ligase, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769771)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.11", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004828 serine-tRNA ligase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006434 seryl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1H5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVY8-1", "uniprot_id": [ { "id": "A0A9J7JVY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVY8", "type": "external" } ], "mass": 85946.0, "length": 755, "protein_name": "Kinesin-like protein", "gene_name": "Kif3a", "organism": "Hamster", "refseq_name": "kinesin-like protein KIF3A isoform X3", "refseq_ac": [ { "id": "XP_027283328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283328", "type": "external" } ], "gene_names_uniprotkb": "Kif3a", "gene_names_refseq": "Kif3a", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF3A isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100755936)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0044877 protein-containing complex binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005874 microtubule;GO:0005929 cilium;GO:0005814 centriole;GO:0016939 kinesin II complex", "go_biological_process": "GO:0010970 transport along microtubule", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JGL1-1", "uniprot_id": [ { "id": "A0A9J7JGL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JGL1", "type": "external" } ], "mass": 161208.0, "length": 1441, "protein_name": "ATP-binding cassette sub-family C member 5", "gene_name": "Abcc5", "organism": "Hamster", "refseq_name": "multidrug resistance-associated protein 5 isoform X1", "refseq_ac": [ { "id": "XP_027268868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268868", "type": "external" } ], "gene_names_uniprotkb": "Abcc5", "gene_names_refseq": "Abcc5", "protein_names_uniprotkb": "ATP-binding cassette sub-family C member 5; 7.6.2.2; Multidrug resistance-associated protein 5", "protein_names_refseq": "multidrug resistance-associated protein 5 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774121)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0015232 heme transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015216 purine nucleotide transmembrane transporter activity", "go_cellular_component": "GO:0005796 Golgi lumen;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0098838 folate transmembrane transport;GO:0030213 hyaluronan biosynthetic process;GO:0140115 export across plasma membrane;GO:0035351 heme transmembrane transport;GO:0070731 cGMP transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JGL1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2S8-1", "uniprot_id": [ { "id": "A0A9J7K2S8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2S8", "type": "external" } ], "mass": 37949.0, "length": 333, "protein_name": "Nicotinamide-nucleotide adenylyltransferase", "gene_name": "Nmnat1", "organism": "Hamster", "refseq_name": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 isoform X1", "refseq_ac": [ { "id": "XP_007650560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650560", "type": "external" } ], "gene_names_uniprotkb": "Nmnat1", "gene_names_refseq": "Nmnat1", "protein_names_uniprotkb": "Nicotinamide-nucleotide adenylyltransferase; 2.7.7.18; 2.7.7.1", "protein_names_refseq": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771233)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615251.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.1", "type": "external" }, { "id": "2.7.7.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.18", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0004515 nicotinate-nucleotide adenylyltransferase activity;GO:0000309 nicotinamide-nucleotide adenylyltransferase activity;GO:0140768 protein ADP-ribosyltransferase-substrate adaptor activity", "go_cellular_component": "GO:0016604 nuclear body;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:1990966 ATP generation from poly-ADP-D-ribose;GO:0034355 NAD+ biosynthetic process via the salvage pathway;GO:0009435 NAD+ biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2S8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWD0-1", "uniprot_id": [ { "id": "A0A9J7JWD0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWD0", "type": "external" } ], "mass": 26728.0, "length": 235, "protein_name": "Prostaglandin E synthase", "gene_name": "Ptges", "organism": "Hamster", "refseq_name": "prostaglandin E synthase isoform X1", "refseq_ac": [ { "id": "XP_007652387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652387", "type": "external" } ], "gene_names_uniprotkb": "Ptges", "gene_names_refseq": "Ptges", "protein_names_uniprotkb": "Prostaglandin E synthase; 2.5.1.18; 5.3.99.3; Glutathione peroxidase PTGES; Glutathione transferase PTGES; Microsomal prostaglandin E synthase 1", "protein_names_refseq": "prostaglandin E synthase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770965)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616253.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Also catalyzes the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "1.11.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.-", "type": "external" }, { "id": "4.4.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0016491 oxidoreductase activity;GO:0050220 prostaglandin-E synthase activity", "go_cellular_component": "GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYQ5-1", "uniprot_id": [ { "id": "A0A9J7JYQ5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYQ5", "type": "external" } ], "mass": 41893.0, "length": 374, "protein_name": "Rab-interacting lysosomal protein", "gene_name": "Rilp", "organism": "Hamster", "refseq_name": "rab-interacting lysosomal protein isoform X1", "refseq_ac": [ { "id": "XP_007653036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653036", "type": "external" } ], "gene_names_uniprotkb": "Rilp", "gene_names_refseq": "Rilp", "protein_names_uniprotkb": "Rab-interacting lysosomal protein", "protein_names_refseq": "rab-interacting lysosomal protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767148)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616958.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0031267 small GTPase binding;GO:0051959 dynein light intermediate chain binding;GO:0032935 sterol sensor activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane;GO:0036064 ciliary basal body;GO:0032991 protein-containing complex", "go_biological_process": "GO:0015031 protein transport;GO:0042632 cholesterol homeostasis;GO:0008333 endosome to lysosome transport;GO:0045022 early endosome to late endosome transport;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0Q7-1", "uniprot_id": [ { "id": "A0A9J7K0Q7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0Q7", "type": "external" } ], "mass": 29302.0, "length": 260, "protein_name": "Ras-related protein Rab-34", "gene_name": "Rab34", "organism": "Hamster", "refseq_name": "ras-related protein Rab-34 isoform X1", "refseq_ac": [ { "id": "XP_007652219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652219", "type": "external" } ], "gene_names_uniprotkb": "Rab34", "gene_names_refseq": "Rab34", "protein_names_uniprotkb": "Ras-related protein Rab-34; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-34 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761520)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616155.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031267 small GTPase binding;GO:0030742 GTP-dependent protein binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0005929 cilium;GO:0048471 perinuclear region of cytoplasm;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0060271 cilium assembly;GO:0043001 Golgi to plasma membrane protein transport;GO:0032418 lysosome localization;GO:0090385 phagosome-lysosome fusion;GO:0019882 antigen processing and presentation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GX15-1", "uniprot_id": [ { "id": "A0A9J7GX15_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GX15", "type": "external" } ], "mass": 64654.0, "length": 570, "protein_name": "TNF receptor-associated factor", "gene_name": "Traf3", "organism": "Hamster", "refseq_name": "TNF receptor-associated factor 3 isoform X1", "refseq_ac": [ { "id": "XP_007630824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007630824", "type": "external" } ], "gene_names_uniprotkb": "Traf3", "gene_names_refseq": "Traf3", "protein_names_uniprotkb": "TNF receptor-associated factor; 2.3.2.27", "protein_names_refseq": "TNF receptor-associated factor 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756323)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 135 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613702.1) and transcript sequence (IACG01030386.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0061630 ubiquitin protein ligase activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005768 endosome;GO:0009898 cytoplasmic side of plasma membrane;GO:0035631 CD40 receptor complex", "go_biological_process": "GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0030162 regulation of proteolysis;GO:0042981 regulation of apoptotic process;GO:0033209 tumor necrosis factor-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GX15-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JA34-1", "uniprot_id": [ { "id": "A0A9J7JA34_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JA34", "type": "external" } ], "mass": 56462.0, "length": 497, "protein_name": "Katanin p60 ATPase-containing subunit A1", "gene_name": "Katna1", "organism": "Hamster", "refseq_name": "katanin p60 ATPase-containing subunit A1 isoform X1", "refseq_ac": [ { "id": "XP_007633845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007633845", "type": "external" } ], "gene_names_uniprotkb": "Katna1; KATNA1", "gene_names_refseq": "Katna1", "protein_names_uniprotkb": "Katanin p60 ATPase-containing subunit A1; 5.6.1.1; Katanin p60 subunit A1; p60 katanin", "protein_names_refseq": "katanin p60 ATPase-containing subunit A1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759022)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613710.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0030496 midbody", "go_biological_process": "GO:0051013 microtubule severing;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JA34-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H8C1-1", "uniprot_id": [ { "id": "A0A9J7H8C1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H8C1", "type": "external" } ], "mass": 19441.0, "length": 176, "protein_name": "Cyclin-dependent kinase inhibitor 1", "gene_name": "Cdkn1a", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase inhibitor 1 isoform X1", "refseq_ac": [ { "id": "XP_035306910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306910", "type": "external" } ], "gene_names_uniprotkb": "Cdkn1a", "gene_names_refseq": "Cdkn1a", "protein_names_uniprotkb": "Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; p21", "protein_names_refseq": "cyclin-dependent kinase inhibitor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103160601)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Also involved in p53-independent DNA damage-induced G2 arrest mediated by CREB3L1 in astrocytes and osteoblasts. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex. Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding. Negatively regulates the CDK4- and CDK6-driven phosphorylation of RB1 in keratinocytes, thereby resulting in the release of E2F1 and subsequent transcription of E2F1-driven G1/S phase promoting genes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0044877 protein-containing complex binding;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0030332 cyclin binding", "go_cellular_component": "GO:0070557 PCNA-p21 complex;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0016604 nuclear body;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:0007507 heart development;GO:0051170 import into nucleus;GO:0007265 Ras protein signal transduction;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H8C1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H6U5-1", "uniprot_id": [ { "id": "A0A9J7H6U5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H6U5", "type": "external" } ], "mass": 53177.0, "length": 461, "protein_name": "Beclin-1", "gene_name": "Becn1", "organism": "Hamster", "refseq_name": "beclin-1 isoform X1", "refseq_ac": [ { "id": "XP_035304112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304112", "type": "external" } ], "gene_names_uniprotkb": "Becn1", "gene_names_refseq": "Becn1", "protein_names_uniprotkb": "Beclin-1", "protein_names_refseq": "beclin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762045)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a central role in autophagy., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0016604 nuclear body;GO:0010008 endosome membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0000045 autophagosome assembly;GO:0051301 cell division;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H6U5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBA7-1", "uniprot_id": [ { "id": "A0A9J7GBA7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBA7", "type": "external" } ], "mass": 149832.0, "length": 1357, "protein_name": "Xanthine dehydrogenase/oxidase", "gene_name": "Xdh", "organism": "Hamster", "refseq_name": "xanthine dehydrogenase/oxidase isoform X3", "refseq_ac": [ { "id": "XP_027281902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281902", "type": "external" } ], "gene_names_uniprotkb": "Xdh", "gene_names_refseq": "Xdh", "protein_names_uniprotkb": "Xanthine dehydrogenase/oxidase; 1.17.1.4; 1.17.3.2", "protein_names_refseq": "xanthine dehydrogenase/oxidase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100766626)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.17.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.1.4", "type": "external" }, { "id": "1.17.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.3.2", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0042803 protein homodimerization activity;GO:0071949 FAD binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0043546 molybdopterin cofactor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005777 peroxisome;GO:0005829 cytosol;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0006154 adenosine catabolic process;GO:0006157 deoxyadenosine catabolic process;GO:0006196 AMP catabolic process;GO:0009115 xanthine catabolic process;GO:0006147 guanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBA7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYC5-1", "uniprot_id": [ { "id": "A0A9J7JYC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYC5", "type": "external" } ], "mass": 48320.0, "length": 433, "protein_name": "Nucleoside diphosphate kinase 7", "gene_name": "Nme7", "organism": "Hamster", "refseq_name": "nucleoside diphosphate kinase 7 isoform X1", "refseq_ac": [ { "id": "XP_035300754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300754", "type": "external" } ], "gene_names_uniprotkb": "Nme7", "gene_names_refseq": "Nme7", "protein_names_uniprotkb": "Nucleoside diphosphate kinase 7; 2.7.11.1; Putative 3'-5'-DNA exonuclease NDK7; Serine protein kinase NME7", "protein_names_refseq": "nucleoside diphosphate kinase 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762945)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Possesses an intrinsic kinase activity. Phosphorylates GSK3B at 'Ser-9', leading to the activation of Wnt/beta-catenin signaling. Additionally, exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing. In vitro, does not seem to have nucleoside diphosphate kinase activity. Functional component of the gamma-tubulin ring complex, implicated in the regulation of its microtubule-nucleating activity in centrosomes, in a kinase activity-dependent manner. May maintain primary cilium assembly and ciliary microtubule stability. Part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, required for motile cilia beating., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" } ], "go_molecular_function": "GO:0008296 3'-5'-DNA exonuclease activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0004550 nucleoside diphosphate kinase activity;GO:0008408 3'-5' exonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005829 cytosol;GO:0036126 sperm flagellum", "go_biological_process": "GO:0010968 regulation of microtubule nucleation;GO:0030317 flagellated sperm motility;GO:0060271 cilium assembly;GO:0006308 DNA catabolic process;GO:0006183 GTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2X7-1", "uniprot_id": [ { "id": "A0A9J7K2X7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2X7", "type": "external" } ], "mass": 107567.0, "length": 971, "protein_name": "Protein 4.1", "gene_name": "Epb41", "organism": "Hamster", "refseq_name": "protein 4.1 isoform X1", "refseq_ac": [ { "id": "XP_027255275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255275", "type": "external" } ], "gene_names_uniprotkb": "Epb41", "gene_names_refseq": "Epb41", "protein_names_uniprotkb": "Protein 4.1; Band 4.1; Erythrocyte membrane protein band 4.1", "protein_names_refseq": "protein 4.1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767741)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0051301 cell division;GO:0031032 actomyosin structure organization;GO:0030866 cortical actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2X7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2Q7-1", "uniprot_id": [ { "id": "A0A9J7K2Q7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2Q7", "type": "external" } ], "mass": 91468.0, "length": 784, "protein_name": "Cyclin-dependent kinase 11B", "gene_name": "LOC100773089", "organism": "Hamster", "refseq_name": "cyclin-dependent kinase 11B isoform X2", "refseq_ac": [ { "id": "XP_027254347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254347", "type": "external" } ], "gene_names_uniprotkb": "LOC100773089", "gene_names_refseq": "LOC100773089", "protein_names_uniprotkb": "Cyclin-dependent kinase 11B; 2.7.11.22; 2.7.11.23; Cell division cycle 2-like protein kinase 1; Cell division protein kinase 11; Cyclin-dependent kinase 11; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1", "protein_names_refseq": "cyclin-dependent kinase 11B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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"type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWX3-1", "uniprot_id": [ { "id": "A0A9J7JWX3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWX3", "type": "external" } ], "mass": 50189.0, "length": 442, "protein_name": "StAR-related lipid transfer protein 3", "gene_name": "Stard3", "organism": "Hamster", "refseq_name": "stAR-related lipid transfer protein 3 isoform X1", "refseq_ac": [ { "id": "XP_027279952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279952", "type": "external" } ], "gene_names_uniprotkb": "Stard3", "gene_names_refseq": "Stard3", "protein_names_uniprotkb": "StAR-related lipid transfer protein 3; START domain-containing protein 3", "protein_names_refseq": "stAR-related lipid transfer protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759029)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015485 cholesterol binding;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031902 late endosome membrane;GO:0140284 endoplasmic reticulum-endosome membrane contact site", "go_biological_process": "GO:0044281 small molecule metabolic process;GO:0030301 cholesterol transport;GO:0008202 steroid metabolic process;GO:0099044 vesicle tethering to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVP3-1", "uniprot_id": [ { "id": "A0A9J7JVP3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVP3", "type": "external" } ], "mass": 94029.0, "length": 821, "protein_name": "Calpain-3", "gene_name": "Capn3", "organism": "Hamster", "refseq_name": "calpain-3 isoform X1", "refseq_ac": [ { "id": "XP_003498099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498099", "type": "external" } ], "gene_names_uniprotkb": "Capn3", "gene_names_refseq": "Capn3", "protein_names_uniprotkb": "Calpain-3; 3.4.22.54", "protein_names_refseq": "calpain-3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758723)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-regulated non-lysosomal thiol-protease., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0043066 negative regulation of apoptotic process;GO:0051592 response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JY95-1", "uniprot_id": [ { "id": "A0A9J7JY95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JY95", "type": "external" } ], "mass": 186441.0, "length": 1712, "protein_name": "Latent-transforming growth factor beta-binding protein 1", "gene_name": "Ltbp1", "organism": "Hamster", "refseq_name": "latent-transforming growth factor beta-binding protein 1 isoform X15", "refseq_ac": [ { "id": "XP_027281878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281878", "type": "external" } ], "gene_names_uniprotkb": "Ltbp1", "gene_names_refseq": "Ltbp1", "protein_names_uniprotkb": "Latent-transforming growth factor beta-binding protein 1; Transforming growth factor beta-1-binding protein 1", "protein_names_refseq": "latent-transforming growth factor beta-binding protein 1 isoform X15", "tax_id": 10029, "disease": "", "pathway": " (cge:100764759)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019838 growth factor binding;GO:0005509 calcium ion binding;GO:0050436 microfibril binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JY95-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWI1-1", "uniprot_id": [ { "id": "A0A9J7JWI1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWI1", "type": "external" } ], "mass": 80254.0, "length": 713, "protein_name": "Epithelial sodium channel subunit alpha", "gene_name": "Scnn1a", "organism": "Hamster", "refseq_name": "amiloride-sensitive sodium channel subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_027284122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284122", "type": "external" } ], "gene_names_uniprotkb": "Scnn1a", "gene_names_refseq": "Scnn1a", "protein_names_uniprotkb": "Epithelial sodium channel subunit alpha; Alpha-NaCH; Amiloride-sensitive sodium channel subunit alpha; Nonvoltage-gated sodium channel 1 subunit alpha; SCNEA", "protein_names_refseq": "amiloride-sensitive sodium channel subunit alpha isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765305)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050699 WW domain binding;GO:0015280 ligand-gated sodium channel activity", "go_cellular_component": "GO:0031514 motile cilium;GO:0016324 apical plasma membrane;GO:0001669 acrosomal vesicle;GO:0034706 sodium channel complex", "go_biological_process": "GO:0006883 intracellular sodium ion homeostasis;GO:0098719 sodium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYW9-1", "uniprot_id": [ { "id": "A0A9J7JYW9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYW9", "type": "external" } ], "mass": 105302.0, "length": 953, "protein_name": "Catenin alpha-2", "gene_name": "Ctnna2", "organism": "Hamster", "refseq_name": "catenin alpha-2 isoform X4", "refseq_ac": [ { "id": "XP_027285253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285253", "type": "external" } ], "gene_names_uniprotkb": "Ctnna2", "gene_names_refseq": "Ctnna2", "protein_names_uniprotkb": "Catenin alpha-2; Alpha N-catenin", "protein_names_refseq": "catenin alpha-2 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100766706)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0005198 structural molecule activity;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005912 adherens junction;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0030424 axon", "go_biological_process": "GO:0016477 cell migration;GO:0030154 cell differentiation;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYW9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K098-1", "uniprot_id": [ { "id": "A0A9J7K098_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K098", "type": "external" } ], "mass": 113352.0, "length": 1003, "protein_name": "Phospholipase", "gene_name": "Pld2", "organism": "Hamster", "refseq_name": "phospholipase D2 isoform X2", "refseq_ac": [ { "id": "XP_035303385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303385", "type": "external" } ], "gene_names_uniprotkb": "Pld2", "gene_names_refseq": "Pld2", "protein_names_uniprotkb": "Phospholipase; 3.1.4.4", "protein_names_refseq": "phospholipase D2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752582)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Function as phospholipase selective for phosphatidylcholine. May have a role in signal-induced cytoskeletal regulation and/or endocytosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.39", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.39", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" } ], "go_molecular_function": "GO:0004630 phospholipase D activity;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0009395 phospholipid catabolic process;GO:0060627 regulation of vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K098-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1P5-1", "uniprot_id": [ { "id": "A0A9J7K1P5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1P5", "type": "external" } ], "mass": 142504.0, "length": 1321, "protein_name": "Zinc finger CCCH domain-containing protein 4", "gene_name": "Zc3h4", "organism": "Hamster", "refseq_name": "zinc finger CCCH domain-containing protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027286835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286835", "type": "external" } ], "gene_names_uniprotkb": "Zc3h4", "gene_names_refseq": "Zc3h4", "protein_names_uniprotkb": "Zinc finger CCCH domain-containing protein 4", "protein_names_refseq": "zinc finger CCCH domain-containing protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767693)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein. Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome. The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0032785 negative regulation of DNA-templated transcription, elongation;GO:0006353 DNA-templated transcription termination;GO:0071027 nuclear RNA surveillance;GO:0110064 lncRNA catabolic process;GO:0140744 negative regulation of lncRNA transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1P5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K283-1", "uniprot_id": [ { "id": "A0A9J7K283_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K283", "type": "external" } ], "mass": 34890.0, "length": 310, "protein_name": "Tafazzin family protein", "gene_name": "Taz", "organism": "Hamster", "refseq_name": "tafazzin isoform X3", "refseq_ac": [ { "id": "XP_027288194", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288194", "type": "external" } ], "gene_names_uniprotkb": "Taz; TAZ", "gene_names_refseq": "Taz", "protein_names_uniprotkb": "Tafazzin family protein", "protein_names_refseq": "tafazzin isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100758692)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0035965 cardiolipin acyl-chain remodeling;GO:0007007 inner mitochondrial membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K283-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K075-1", "uniprot_id": [ { "id": "A0A9J7K075_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K075", "type": "external" } ], "mass": 52853.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838723", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X1", "refseq_ac": [ { "id": "XP_027290071", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290071", "type": "external" } ], "gene_names_uniprotkb": "LOC113838723", "gene_names_refseq": "LOC113838723", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113838723)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K075-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0C0-1", "uniprot_id": [ { "id": "A0A9J7K0C0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0C0", "type": "external" } ], "mass": 52638.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113839093", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X3", "refseq_ac": [ { "id": "XP_027290349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290349", "type": "external" } ], "gene_names_uniprotkb": "LOC113839093", "gene_names_refseq": "LOC113839093", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:113839093)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K0C0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H757-1", "uniprot_id": [ { "id": "A0A9J7H757_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H757", "type": "external" } ], "mass": 48072.0, "length": 434, "protein_name": "Alpha-tubulin N-acetyltransferase 1", "gene_name": "Atat1", "organism": "Hamster", "refseq_name": "alpha-tubulin N-acetyltransferase 1 isoform X3", "refseq_ac": [ { "id": "XP_035306822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306822", "type": "external" } ], "gene_names_uniprotkb": "Atat1; ATAT1; MEC17", "gene_names_refseq": "Atat1", "protein_names_uniprotkb": "Alpha-tubulin N-acetyltransferase 1; 2.3.1.108; Acetyltransferase mec-17 homolog; Alpha-TAT1; Alpha-TAT; TAT", "protein_names_refseq": "alpha-tubulin N-acetyltransferase 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100764669)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.108", "type": "external" } ], "go_molecular_function": "GO:0019799 tubulin N-acetyltransferase activity;GO:0004468 L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005874 microtubule;GO:0005905 clathrin-coated pit;GO:0005925 focal adhesion", "go_biological_process": "GO:0048666 neuron development;GO:0070507 regulation of microtubule cytoskeleton organization;GO:0009612 response to mechanical stimulus;GO:0000226 microtubule cytoskeleton organization;GO:0048265 response to pain", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H757-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYS3-1", "uniprot_id": [ { "id": "A0A9J7JYS3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYS3", "type": "external" } ], "mass": 45009.0, "length": 397, "protein_name": "Cystinosin", "gene_name": "Ctns", "organism": "Hamster", "refseq_name": "cystinosin isoform X7", "refseq_ac": [ { "id": "XP_027282602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282602", "type": "external" } ], "gene_names_uniprotkb": "Ctns", "gene_names_refseq": "Ctns", "protein_names_uniprotkb": "Cystinosin", "protein_names_refseq": "cystinosin isoform X7", "tax_id": 10029, "disease": "", "pathway": " (cge:100764451)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cystine/H(+) symporter that mediates export of cystine, the oxidized dimer of cysteine, from lysosomes. Plays an important role in melanin synthesis by catalyzing cystine export from melanosomes, possibly by inhibiting pheomelanin synthesis. In addition to cystine export, also acts as a positive regulator of mTORC1 signaling in kidney proximal tubular cells, via interactions with components of the v-ATPase and Ragulator complexes. Also involved in small GTPase-regulated vesicle trafficking and lysosomal localization of LAMP2A, independently of cystine transporter activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015295 solute:proton symporter activity;GO:0015184 L-cystine transmembrane transporter activity;GO:0015293 symporter activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0005770 late endosome;GO:0033162 melanosome membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0015031 protein transport;GO:0050890 cognition;GO:0007420 brain development;GO:0046034 ATP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J6W2-1", "uniprot_id": [ { "id": "A0A9J7J6W2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J6W2", "type": "external" } ], "mass": 54233.0, "length": 485, "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "organism": "Hamster", "refseq_name": "lipoprotein lipase isoform X1", "refseq_ac": [ { "id": "XP_027244681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244681", "type": "external" } ], "gene_names_uniprotkb": "Lpl", "gene_names_refseq": "Lpl", "protein_names_uniprotkb": "Lipoprotein lipase; 3.1.1.34; LPL", "protein_names_refseq": "lipoprotein lipase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689191)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0008201 heparin binding;GO:0034185 apolipoprotein binding;GO:0042803 protein homodimerization activity;GO:0043395 heparan sulfate proteoglycan binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron", "go_biological_process": "GO:0031670 cellular response to nutrient;GO:1904179 positive regulation of adipose tissue development;GO:0001523 retinoid metabolic process;GO:0045600 positive regulation of fat cell differentiation;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J6W2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HD75-1", "uniprot_id": [ { "id": "A0A9J7HD75_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HD75", "type": "external" } ], "mass": 50513.0, "length": 455, "protein_name": "Retinoic acid receptor beta", "gene_name": "Rarb", "organism": "Hamster", "refseq_name": "retinoic acid receptor beta isoform X1", "refseq_ac": [ { "id": "XP_035307698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307698", "type": "external" } ], "gene_names_uniprotkb": "Rarb", "gene_names_refseq": "Rarb", "protein_names_uniprotkb": "Retinoic acid receptor beta; Nuclear receptor subfamily 1 group B member 2", "protein_names_refseq": "retinoic acid receptor beta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768698)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613720.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0035259 nuclear glucocorticoid receptor binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0002068 glandular epithelial cell development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HD75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JIW6-1", "uniprot_id": [ { "id": "A0A9J7JIW6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JIW6", "type": "external" } ], "mass": 106882.0, "length": 967, "protein_name": "Serine/threonine-protein kinase N1", "gene_name": "Pkn1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase N1 isoform X3", "refseq_ac": [ { "id": "XP_027261954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261954", "type": "external" } ], "gene_names_uniprotkb": "Pkn1", "gene_names_refseq": "Pkn1", "protein_names_uniprotkb": "Serine/threonine-protein kinase N1; 2.7.11.13; Protein kinase C-like 1; Protein kinase C-like PKN; Protein-kinase C-related kinase 1; Serine-threonine protein kinase N", "protein_names_refseq": "serine/threonine-protein kinase N1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752729)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0031267 small GTPase binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032154 cleavage furrow;GO:0030496 midbody", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JIW6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JLH7-1", "uniprot_id": [ { "id": "A0A9J7JLH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JLH7", "type": "external" } ], "mass": 88597.0, "length": 787, "protein_name": "Serine/threonine-protein kinase MARK2", "gene_name": "Mark2", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase MARK2 isoform X2", "refseq_ac": [ { "id": "XP_027264204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264204", "type": "external" } ], "gene_names_uniprotkb": "Mark2", "gene_names_refseq": "Mark2", "protein_names_uniprotkb": "Serine/threonine-protein kinase MARK2; 2.7.11.1; 2.7.11.26; ELKL motif kinase 1; MAP/microtubule affinity-regulating kinase 2", "protein_names_refseq": "serine/threonine-protein kinase MARK2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769644)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 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"type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": 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"go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008289 lipid binding;GO:0050321 tau-protein kinase activity;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030425 dendrite;GO:0016328 lateral plasma membrane;GO:0005829 cytosol", "go_biological_process": "GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0016055 Wnt signaling pathway;GO:0000226 microtubule cytoskeleton organization;GO:0050770 regulation of axonogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JLH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GWG6-1", "uniprot_id": [ { "id": "A0A9J7GWG6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GWG6", "type": "external" } ], "mass": 149686.0, "length": 1324, "protein_name": "Toll-like receptor 9", "gene_name": "Tlr9", "organism": "Hamster", "refseq_name": "toll-like receptor 9 isoform X2", "refseq_ac": [ { "id": "XP_035299803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299803", "type": "external" } ], "gene_names_uniprotkb": "Tlr9", "gene_names_refseq": "Tlr9", "protein_names_uniprotkb": "Toll-like receptor 9", "protein_names_refseq": "toll-like receptor 9 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103160136)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also acts via ADCY7, leading to cyclic di-AMP (c-di-AMP) synthesis and activation of the NLRP3 inflammasome. Plays a role in defense against systemic mouse cytomegalovirus infection. Controls lymphocyte response to Helicobacter infection. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003785 actin monomer binding;GO:0005524 ATP binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding;GO:0005080 protein kinase C binding", "go_cellular_component": "GO:0005884 actin filament;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0048471 perinuclear region of cytoplasm;GO:0030175 filopodium", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:0071300 cellular response to retinoic acid;GO:0051016 barbed-end actin filament capping;GO:0071363 cellular response to growth factor stimulus;GO:0045773 positive regulation of axon extension", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GWG6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GFY2-1", "uniprot_id": [ { "id": "A0A9J7GFY2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GFY2", "type": "external" } ], "mass": 85460.0, "length": 771, "protein_name": "Lysyl oxidase homolog", "gene_name": "Loxl3", "organism": "Hamster", "refseq_name": "lysyl oxidase homolog 3 isoform X1", "refseq_ac": [ { "id": "XP_016835522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835522", "type": "external" } ], "gene_names_uniprotkb": "Loxl3", "gene_names_refseq": "Loxl3", "protein_names_uniprotkb": "Lysyl oxidase homolog; 1.4.3.13", "protein_names_refseq": "lysyl oxidase homolog 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760335)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 4 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615037.1) and transcript sequence (IACG01013004.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0001968 fibronectin binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0021510 spinal cord development;GO:0030324 lung development;GO:0045892 negative regulation of DNA-templated transcription;GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GFY2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H2D3-1", "uniprot_id": [ { "id": "A0A9J7H2D3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H2D3", "type": "external" } ], "mass": 589808.0, "length": 5214, "protein_name": "E3 ubiquitin-protein ligase RNF213", "gene_name": "Rnf213", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase RNF213 isoform X1", "refseq_ac": [ { "id": "XP_035293728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293728", "type": "external" } ], "gene_names_uniprotkb": "Rnf213", "gene_names_refseq": "Rnf213", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF213; 2.3.2.27; E3 ubiquitin-lipopolysaccharide ligase RNF213; Mysterin; RING finger protein 213", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF213 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753392)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0042742 defense response to bacterium;GO:0002040 sprouting angiogenesis;GO:0006511 ubiquitin-dependent protein catabolic process;GO:2000051 negative regulation of non-canonical Wnt signaling pathway;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H2D3-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H2C6-1", "uniprot_id": [ { "id": "A0A9J7H2C6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H2C6", "type": "external" } ], "mass": 90587.0, "length": 803, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgkb", "organism": "Hamster", "refseq_name": "diacylglycerol kinase beta isoform X2", "refseq_ac": [ { "id": "XP_035301324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301324", "type": "external" } ], "gene_names_uniprotkb": "Dgkb", "gene_names_refseq": "Dgkb", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase beta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753343)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has a higher activity with long-chain diacylglycerols like 1,2-di-(9Z-octadecenoyl)-sn-glycerol compared to 1,2-didecanoyl-sn-glycerol. Specifically expressed in brain, it regulates neuron-specific morphological changes including neurite branching and neurite spine formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0045211 postsynaptic membrane;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0050804 modulation of chemical synaptic transmission;GO:0046486 glycerolipid metabolic process;GO:0099175 regulation of postsynapse organization;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H2C6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H5Z0-1", "uniprot_id": [ { "id": "A0A9J7H5Z0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H5Z0", "type": "external" } ], "mass": 133412.0, "length": 1207, "protein_name": "Nitric oxide synthase", "gene_name": "Nos3", "organism": "Hamster", "refseq_name": "nitric oxide synthase, endothelial isoform X2", "refseq_ac": [ { "id": "XP_035304505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304505", "type": "external" } ], "gene_names_uniprotkb": "Nos3", "gene_names_refseq": "Nos3", "protein_names_uniprotkb": "Nitric oxide synthase; 1.14.13.39", "protein_names_refseq": "nitric oxide synthase, endothelial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769961)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Produces nitric oxide (NO) which is a messenger molecule with diverse functions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" } ], "go_molecular_function": "GO:0004517 nitric-oxide synthase activity;GO:0034617 tetrahydrobiopterin binding;GO:0003785 actin monomer binding;GO:0005516 calmodulin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton;GO:0005901 caveola", "go_biological_process": "GO:0014740 negative regulation of muscle hyperplasia;GO:0014806 smooth muscle hyperplasia;GO:0032496 response to lipopolysaccharide;GO:0001974 blood vessel remodeling;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H5Z0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GUR3-1", "uniprot_id": [ { "id": "A0A9J7GUR3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GUR3", "type": "external" } ], "mass": 97432.0, "length": 861, "protein_name": "Protein argonaute-2", "gene_name": "Ago2", "organism": "Hamster", "refseq_name": "protein argonaute-2 isoform X1", "refseq_ac": [ { "id": "XP_035296547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296547", "type": "external" } ], "gene_names_uniprotkb": "Ago2; AGO2; EIF2C2", "gene_names_refseq": "Ago2", "protein_names_uniprotkb": "Protein argonaute-2; 3.1.26.n2; Argonaute2; Eukaryotic translation initiation factor 2C 2; Protein slicer; eIF-2C 2; eIF2C 2", "protein_names_refseq": "protein argonaute-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760040)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. May inhibit translation initiation by binding to the 7-methylguanosine cap, thereby preventing the recruitment of the translation initiation factor eIF4-E. May also inhibit translation initiation via interaction with EIF6, which itself binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur. In some cases RISC-mediated translational repression is also observed for miRNAs that perfectly match the 3' untranslated region (3'-UTR). Can also up-regulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and up-regulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding;GO:0035198 miRNA binding;GO:0000340 RNA 7-methylguanosine cap binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0030425 dendrite;GO:0070062 extracellular exosome", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045766 positive regulation of angiogenesis;GO:0045947 negative regulation of translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GUR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GJE4-1", "uniprot_id": [ { "id": "A0A9J7GJE4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GJE4", "type": "external" } ], "mass": 57585.0, "length": 515, "protein_name": "Serine/threonine-protein kinase 3", "gene_name": "Stk3", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase 3 isoform X3", "refseq_ac": [ { "id": "XP_027287315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287315", "type": "external" } ], "gene_names_uniprotkb": "Stk3", "gene_names_refseq": "Stk3", "protein_names_uniprotkb": "Serine/threonine-protein kinase 3; 2.7.11.1; Mammalian STE20-like protein kinase 2; STE20-like kinase MST2", "protein_names_refseq": "serine/threonine-protein kinase 3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100763795)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0140537 transcription regulator activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0046621 negative regulation of organ growth;GO:0060706 cell differentiation involved in embryonic placenta development;GO:0045600 positive regulation of fat cell differentiation;GO:0051262 protein tetramerization;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GJE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H750-1", "uniprot_id": [ { "id": "A0A9J7H750_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H750", "type": "external" } ], "mass": 136396.0, "length": 1208, "protein_name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "gene_name": "Pan2", "organism": "Hamster", "refseq_name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X15", "refseq_ac": [ { "id": "XP_035306309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306309", "type": "external" } ], "gene_names_uniprotkb": "Pan2; PAN2", "gene_names_refseq": "Pan2", "protein_names_uniprotkb": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2; 3.1.13.4; Inactive ubiquitin carboxyl-terminal hydrolase 52; PAB1P-dependent poly(A)-specific ribonuclease; PAN deadenylation complex subunit 2; Poly(A)-nuclease deadenylation complex subunit 2", "protein_names_refseq": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X15", "tax_id": 10029, "disease": "", "pathway": " (cge:100765354)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0031251 PAN complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H750-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JAB2-1", "uniprot_id": [ { "id": "A0A9J7JAB2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JAB2", "type": "external" } ], "mass": 53344.0, "length": 478, "protein_name": "Serine/threonine-protein kinase 24", "gene_name": "Stk24", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase 24 isoform X1", "refseq_ac": [ { "id": "XP_007619489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619489", "type": "external" } ], "gene_names_uniprotkb": "Stk24", "gene_names_refseq": "Stk24", "protein_names_uniprotkb": "Serine/threonine-protein kinase 24; 2.7.11.1; Mammalian STE20-like protein kinase 3; STE20-like kinase MST3", "protein_names_refseq": "serine/threonine-protein kinase 24 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761115)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613586.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0048679 regulation of axon regeneration;GO:0006915 apoptotic process;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JAB2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7E9-1", "uniprot_id": [ { "id": "A0A9J7G7E9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7E9", "type": "external" } ], "mass": 139712.0, "length": 1271, "protein_name": "Activating molecule in BECN1-regulated autophagy protein 1", "gene_name": "Ambra1", "organism": "Hamster", "refseq_name": "activating molecule in BECN1-regulated autophagy protein 1 isoform X2", "refseq_ac": [ { "id": "XP_007608171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007608171", "type": "external" } ], "gene_names_uniprotkb": "Ambra1", "gene_names_refseq": "Ambra1", "protein_names_uniprotkb": "Activating molecule in BECN1-regulated autophagy protein 1", "protein_names_refseq": "activating molecule in BECN1-regulated autophagy protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613646.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0031625 ubiquitin protein ligase binding;GO:0051020 GTPase binding;GO:0019903 protein phosphatase binding;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7E9-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GDZ1-1", "uniprot_id": [ { "id": "A0A9J7GDZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GDZ1", "type": "external" } ], "mass": 56605.0, "length": 508, "protein_name": "Aldehyde dehydrogenase", "gene_name": "LOC100757658", "organism": "Hamster", "refseq_name": "aldehyde dehydrogenase family 3 member A2 isoform X3", "refseq_ac": [ { "id": "XP_027283056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283056", "type": "external" } ], "gene_names_uniprotkb": "LOC100757658", "gene_names_refseq": "LOC100757658", "protein_names_uniprotkb": "Aldehyde dehydrogenase", "protein_names_refseq": "aldehyde dehydrogenase family 3 member A2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.19", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.47", "type": "external" }, { "id": "1.2.1.46", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.46", "type": "external" }, { "id": "1.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.31", "type": "external" }, { "id": "1.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004028 3-chloroallyl aldehyde dehydrogenase activity;GO:0120553 farnesal dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006081 aldehyde metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GDZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JNU2-1", "uniprot_id": [ { "id": "A0A9J7JNU2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JNU2", "type": "external" } ], "mass": 120326.0, "length": 1087, "protein_name": "Activated CDC42 kinase 1", "gene_name": "Tnk2", "organism": "Hamster", "refseq_name": "activated CDC42 kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_027268633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268633", "type": "external" } ], "gene_names_uniprotkb": "Tnk2", "gene_names_refseq": "Tnk2", "protein_names_uniprotkb": "Activated CDC42 kinase 1; 2.7.10.2; 2.7.11.1; Tyrosine kinase non-receptor protein 2", "protein_names_refseq": "activated CDC42 kinase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754061)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway;GO:0045616 regulation of keratinocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JNU2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZI9-1", "uniprot_id": [ { "id": "A0A9J7JZI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZI9", "type": "external" } ], "mass": 39977.0, "length": 358, "protein_name": "Renin receptor", "gene_name": "Atp6ap2", "organism": "Hamster", "refseq_name": "renin receptor isoform X5", "refseq_ac": [ { "id": "XP_027288990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288990", "type": "external" } ], "gene_names_uniprotkb": "Atp6ap2", "gene_names_refseq": "Atp6ap2", "protein_names_uniprotkb": "Renin receptor; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; Renin/prorenin receptor", "protein_names_refseq": "renin receptor isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100768578)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (V-ATPase) and the acidification of the endo-lysosomal system. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS). Through its function in V-type ATPase (v-ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0009897 external side of plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0060323 head morphogenesis;GO:0032914 positive regulation of transforming growth factor beta1 production;GO:0021903 rostrocaudal neural tube patterning;GO:0002003 angiotensin maturation;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWK1-1", "uniprot_id": [ { "id": "A0A9J7JWK1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWK1", "type": "external" } ], "mass": 131387.0, "length": 1187, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rc3h2", "organism": "Hamster", "refseq_name": "roquin-2 isoform X2", "refseq_ac": [ { "id": "XP_027279332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279332", "type": "external" } ], "gene_names_uniprotkb": "Rc3h2", "gene_names_refseq": "Rc3h2", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "roquin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773428)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0009986 cell surface;GO:0016020 membrane;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0050852 T cell receptor signaling pathway;GO:0048536 spleen development;GO:0043029 T cell homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWK1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GRQ0-1", "uniprot_id": [ { "id": "A0A9J7GRQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GRQ0", "type": "external" } ], "mass": 27812.0, "length": 245, "protein_name": "Adenylate kinase isoenzyme 6", "gene_name": "Ak6", "organism": "Hamster", "refseq_name": "adenylate kinase isoenzyme 6 isoform X2", "refseq_ac": [ { "id": "XP_035296423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296423", "type": "external" } ], "gene_names_uniprotkb": "Ak6; AK6; CINAP", "gene_names_refseq": "Ak6", "protein_names_uniprotkb": "Adenylate kinase isoenzyme 6; 2.7.4.3; AK/ATPase; AK6; Coilin-interacting nuclear ATPase protein; Dual activity adenylate kinase/ATPase", "protein_names_refseq": "adenylate kinase isoenzyme 6 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768838)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis. May be involved in regulation of Cajal body (CB) formation., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.10", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.14", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0015030 Cajal body", "go_biological_process": "GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GRQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HAE3-1", "uniprot_id": [ { "id": "A0A9J7HAE3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HAE3", "type": "external" } ], "mass": 48216.0, "length": 420, "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "Fdps", "organism": "Hamster", "refseq_name": "farnesyl pyrophosphate synthase isoform X2", "refseq_ac": [ { "id": "XP_035306396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306396", "type": "external" } ], "gene_names_uniprotkb": "Fdps", "gene_names_refseq": "Fdps", "protein_names_uniprotkb": "Farnesyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.10; 2.5.1.1; Cholesterol-regulated 39 kDa protein; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Geranyltranstransferase", "protein_names_refseq": "farnesyl pyrophosphate synthase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754883)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.1", "type": "external" }, { "id": "2.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.10", "type": "external" }, { "id": "2.5.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.29", "type": "external" } ], "go_molecular_function": "GO:0004161 dimethylallyltranstransferase activity;GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0033386 geranylgeranyl diphosphate biosynthetic process;GO:0033489 cholesterol biosynthetic process via desmosterol;GO:0033490 cholesterol biosynthetic process via lathosterol;GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway;GO:0036197 zymosterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HAE3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JAQ7-1", "uniprot_id": [ { "id": "A0A9J7JAQ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JAQ7", "type": "external" } ], "mass": 57056.0, "length": 511, "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "Mdm2", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase Mdm2 isoform X3", "refseq_ac": [ { "id": "XP_027248139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248139", "type": "external" } ], "gene_names_uniprotkb": "Mdm2", "gene_names_refseq": "Mdm2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Mdm2; 2.3.2.27; Double minute 2 protein; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2", "protein_names_refseq": "E3 ubiquitin-protein ligase Mdm2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770120)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0002039 p53 binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0045931 positive regulation of mitotic cell cycle;GO:0006915 apoptotic process;GO:0016567 protein ubiquitination;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JAQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JBP2-1", "uniprot_id": [ { "id": "A0A9J7JBP2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JBP2", "type": "external" } ], "mass": 41569.0, "length": 378, "protein_name": "CCN family member 1", "gene_name": "Ccn1", "organism": "Hamster", "refseq_name": "CCN family member 1 isoform X1", "refseq_ac": [ { "id": "XP_003512990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512990", "type": "external" } ], "gene_names_uniprotkb": "Ccn1", "gene_names_refseq": "Ccn1", "protein_names_uniprotkb": "CCN family member 1; Cellular communication network factor 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; Protein CYR61", "protein_names_refseq": "CCN family member 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766753)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615663.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003512990.2. COMPLETENESS: full length., [RefSeq]; Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0019838 growth factor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006935 chemotaxis;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0030335 positive regulation of cell migration;GO:0045597 positive regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JBP2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GP70-1", "uniprot_id": [ { "id": "A0A9J7GP70_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GP70", "type": "external" } ], "mass": 845043.0, "length": 7463, "protein_name": "Actin cross-linking family 7", "gene_name": "Macf1", "organism": "Hamster", "refseq_name": "microtubule-actin cross-linking factor 1 isoform X1", "refseq_ac": [ { "id": "XP_035295526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295526", "type": "external" } ], "gene_names_uniprotkb": "Macf1", "gene_names_refseq": "Macf1", "protein_names_uniprotkb": "Actin cross-linking family 7", "protein_names_refseq": "microtubule-actin cross-linking factor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770726)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0005198 structural molecule activity;GO:0005509 calcium ion binding;GO:0045296 cadherin binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005874 microtubule;GO:0015629 actin cytoskeleton;GO:0005882 intermediate filament;GO:0032587 ruffle membrane", "go_biological_process": "GO:0051893 regulation of focal adhesion assembly;GO:0016055 Wnt signaling pathway;GO:0032886 regulation of microtubule-based process;GO:0042060 wound healing;GO:0045104 intermediate filament cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GP70-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JF18-1", "uniprot_id": [ { "id": "A0A9J7JF18_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JF18", "type": "external" } ], "mass": 533678.0, "length": 4687, "protein_name": "Plectin", "gene_name": "LOC113834516", "organism": "Hamster", "refseq_name": "plectin isoform X2", "refseq_ac": [ { "id": "XP_027259949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259949", "type": "external" } ], "gene_names_uniprotkb": "LOC113834516", "gene_names_refseq": "LOC113834516", "protein_names_uniprotkb": "Plectin; Plectin-1", "protein_names_refseq": "plectin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113834516)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005200 structural constituent of cytoskeleton;GO:0045296 cadherin binding;GO:0008307 structural constituent of muscle;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0048471 perinuclear region of cytoplasm;GO:0005882 intermediate filament;GO:0002102 podosome;GO:0042383 sarcolemma", "go_biological_process": "GO:0042060 wound healing;GO:0031581 hemidesmosome assembly;GO:0045104 intermediate filament cytoskeleton organization;GO:0031667 response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JF18-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JG17-1", "uniprot_id": [ { "id": "A0A9J7JG17_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JG17", "type": "external" } ], "mass": 62170.0, "length": 548, "protein_name": "Alpha-ketoglutarate-dependent dioxygenase FTO", "gene_name": "Fto", "organism": "Hamster", "refseq_name": "alpha-ketoglutarate-dependent dioxygenase FTO isoform X1", "refseq_ac": [ { "id": "XP_027260698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260698", "type": "external" } ], "gene_names_uniprotkb": "Fto", "gene_names_refseq": "Fto", "protein_names_uniprotkb": "Alpha-ketoglutarate-dependent dioxygenase FTO; 1.14.11.53; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO", "protein_names_refseq": "alpha-ketoglutarate-dependent dioxygenase FTO isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771560)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613676.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027260698.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.53", "type": "external" }, { "id": "1.14.11.51", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.51", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "1.14.11.33", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.33", "type": "external" } ], "go_molecular_function": "GO:0008198 ferrous iron binding;GO:1990931 mRNA N6-methyladenosine dioxygenase activity;GO:0035516 broad specificity oxidative DNA demethylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0040014 regulation of multicellular organism growth;GO:0006307 DNA alkylation repair;GO:0042245 RNA repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JG17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JHX6-1", "uniprot_id": [ { "id": "A0A9J7JHX6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JHX6", "type": "external" } ], "mass": 61085.0, "length": 552, "protein_name": "TGF-beta receptor type-1", "gene_name": "Tgfbr1", "organism": "Hamster", "refseq_name": "TGF-beta receptor type-1 isoform X2", "refseq_ac": [ { "id": "XP_027258931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258931", "type": "external" } ], "gene_names_uniprotkb": "Tgfbr1", "gene_names_refseq": "Tgfbr1", "protein_names_uniprotkb": "TGF-beta receptor type-1; 2.7.11.30; Transforming growth factor-beta receptor type I", "protein_names_refseq": "TGF-beta receptor type-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772727)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005025 transforming growth factor beta receptor activity, type I;GO:0046332 SMAD binding;GO:0050431 transforming growth factor beta binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0045121 membrane raft", "go_biological_process": "GO:0097305 response to alcohol;GO:0007507 heart development;GO:0030154 cell differentiation;GO:0006915 apoptotic process;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JHX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JNS8-1", "uniprot_id": [ { "id": "A0A9J7JNS8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JNS8", "type": "external" } ], "mass": 89159.0, "length": 790, "protein_name": "Amyloid beta precursor like protein 2", "gene_name": "Aplp2", "organism": "Hamster", "refseq_name": "amyloid-like protein 2 isoform X5", "refseq_ac": [ { "id": "XP_027267545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267545", "type": "external" } ], "gene_names_uniprotkb": "Aplp2", "gene_names_refseq": "Aplp2", "protein_names_uniprotkb": "Amyloid beta precursor like protein 2; Amyloid beta (A4) precursor-like protein 2; Amyloid protein homolog; Amyloid-like protein 2; CDEI box-binding protein; Sperm membrane protein YWK-II", "protein_names_refseq": "amyloid-like protein 2 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100758329)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0008201 heparin binding;GO:0046914 transition metal ion binding;GO:0140677 molecular function activator activity", "go_cellular_component": "GO:0099503 secretory vesicle;GO:0009986 cell surface;GO:0016020 membrane;GO:0012505 endomembrane system;GO:0043005 neuron projection", "go_biological_process": "GO:0007409 axonogenesis;GO:0007417 central nervous system development;GO:0051246 regulation of protein metabolic process;GO:0010604 positive regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JNS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JNF4-1", "uniprot_id": [ { "id": "A0A9J7JNF4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JNF4", "type": "external" } ], "mass": 92932.0, "length": 823, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16", "gene_name": "Usp16", "organism": "Hamster", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 16 isoform X1", "refseq_ac": [ { "id": "XP_027268148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268148", "type": "external" } ], "gene_names_uniprotkb": "Usp16; USP16", "gene_names_refseq": "Usp16", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 16; 3.4.19.12; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-specific-processing protease 16", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 16 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. Also deubiquitinates non-histone proteins, such as ribosomal protein RPS27A: deubiquitination of monoubiquitinated RPS27A promotes maturation of the 40S ribosomal subunit. Also mediates deubiquitination of tektin proteins (TEKT1, TEKT2, TEK3, TEKT4 and TEKT5), promoting their stability., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0043130 ubiquitin binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0051289 protein homotetramerization;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JNF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JRD9-1", "uniprot_id": [ { "id": "A0A9J7JRD9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JRD9", "type": "external" } ], "mass": 194459.0, "length": 1714, "protein_name": "Intersectin-1", "gene_name": "Itsn1", "organism": "Hamster", "refseq_name": "intersectin-1 isoform X5", "refseq_ac": [ { "id": "XP_027271400", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271400", "type": "external" } ], "gene_names_uniprotkb": "Itsn1", "gene_names_refseq": "Itsn1", "protein_names_uniprotkb": "Intersectin-1", "protein_names_refseq": "intersectin-1 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100758619)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as a guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex. Plays a role in the assembly and maturation of clathrin-coated vesicles. Recruits FCHSD2 to clathrin-coated pits. Involved in endocytosis of activated EGFR, and probably also other growth factor receptors. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Promotes ubiquitination and subsequent degradation of EGFR, and thereby contributes to the down-regulation of EGFR-dependent signaling pathways. In chromaffin cells, required for normal exocytosis of catecholamines. Required for rapid replenishment of release-ready synaptic vesicles at presynaptic active zones. Inhibits ARHGAP31 activity toward RAC1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a role in synaptic vesicle endocytosis in brain neurons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005509 calcium ion binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005905 clathrin-coated pit;GO:0030027 lamellipodium;GO:0055037 recycling endosome;GO:0043005 neuron projection", "go_biological_process": "GO:0015031 protein transport;GO:0006887 exocytosis;GO:0023051 regulation of signaling;GO:0010646 regulation of cell communication;GO:0150007 clathrin-dependent synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JRD9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JJV6-1", "uniprot_id": [ { "id": "A0A9J7JJV6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JJV6", "type": "external" } ], "mass": 88996.0, "length": 799, "protein_name": "Serine/threonine-protein kinase MARK1", "gene_name": "Mark1", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase MARK1 isoform X1", "refseq_ac": [ { "id": "XP_016831482", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831482", "type": "external" } ], "gene_names_uniprotkb": "Mark1", "gene_names_refseq": "Mark1", "protein_names_uniprotkb": "Serine/threonine-protein kinase MARK1; 2.7.11.1; 2.7.11.26; MAP/microtubule affinity-regulating kinase 1", "protein_names_refseq": "serine/threonine-protein kinase MARK1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757648)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613581.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008289 lipid binding;GO:0050321 tau-protein kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0042995 cell projection;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JJV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JM23-1", "uniprot_id": [ { "id": "A0A9J7JM23_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JM23", "type": "external" } ], "mass": 85296.0, "length": 773, "protein_name": "CD44 antigen", "gene_name": "Cd44", "organism": "Hamster", "refseq_name": "CD44 antigen isoform X1", "refseq_ac": [ { "id": "XP_027278176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278176", "type": "external" } ], "gene_names_uniprotkb": "Cd44", "gene_names_refseq": "Cd44", "protein_names_uniprotkb": "CD44 antigen; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; Phagocytic glycoprotein I", "protein_names_refseq": "CD44 antigen isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750640)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005540 hyaluronic acid binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0005902 microvillus;GO:0035692 macrophage migration inhibitory factor receptor complex", "go_biological_process": "GO:0048731 system development;GO:0006954 inflammatory response;GO:0007155 cell adhesion;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JM23-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G7W0-1", "uniprot_id": [ { "id": "A0A9J7G7W0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G7W0", "type": "external" } ], "mass": 28054.0, "length": 254, "protein_name": "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1", "gene_name": "Ptpmt1", "organism": "Hamster", "refseq_name": "phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform X2", "refseq_ac": [ { "id": "XP_027278403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278403", "type": "external" } ], "gene_names_uniprotkb": "Ptpmt1", "gene_names_refseq": "Ptpmt1", "protein_names_uniprotkb": "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; 3.1.3.16; 3.1.3.27; Protein-tyrosine phosphatase mitochondrial 1", "protein_names_refseq": "phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763640)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. Prevents intrinsic apoptosis, by regulating mitochondrial membrane integrity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008962 phosphatidylglycerophosphatase activity;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0016020 membrane", "go_biological_process": "GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G7W0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G830-1", "uniprot_id": [ { "id": "A0A9J7G830_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G830", "type": "external" } ], "mass": 48517.0, "length": 454, "protein_name": "Adenylyltransferase and sulfurtransferase MOCS3", "gene_name": "LOC100761655", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: adenylyltransferase and sulfurtransferase MOCS3", "refseq_ac": [ { "id": "XP_027279137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279137", "type": "external" } ], "gene_names_uniprotkb": "LOC100761655; MOCS3; UBA4", "gene_names_refseq": "LOC100761655", "protein_names_uniprotkb": "Adenylyltransferase and sulfurtransferase MOCS3; Adenylyltransferase MOCS3; Molybdenum cofactor synthesis protein 3; Sulfur carrier protein MOCS2A adenylyltransferase; Sulfur carrier protein MOCS2A sulfurtransferase; Sulfurtransferase MOCS3", "protein_names_refseq": "LOW QUALITY PROTEIN: adenylyltransferase and sulfurtransferase MOCS3", "tax_id": 10029, "disease": "", "pathway": " (cge:100761655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.80", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.80", "type": "external" }, { "id": "2.8.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.11", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004792 thiosulfate-cyanide sulfurtransferase activity;GO:0042292 URM1 activating enzyme activity;GO:0061604 molybdopterin-synthase sulfurtransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation;GO:0006777 Mo-molybdopterin cofactor biosynthetic process;GO:0032447 protein urmylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G830-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G8Q3-1", "uniprot_id": [ { "id": "A0A9J7G8Q3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G8Q3", "type": "external" } ], "mass": 40927.0, "length": 363, "protein_name": "Adenosine deaminase", "gene_name": "Ada", "organism": "Hamster", "refseq_name": "adenosine deaminase", "refseq_ac": [ { "id": "XP_027279285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279285", "type": "external" } ], "gene_names_uniprotkb": "Ada", "gene_names_refseq": "Ada", "protein_names_uniprotkb": "Adenosine deaminase; 3.5.4.4; Adenosine aminohydrolase", "protein_names_refseq": "adenosine deaminase", "tax_id": 10029, "disease": "", "pathway": " (cge:100756254)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "2.4.2.28", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.28", "type": "external" } ], "go_molecular_function": "GO:0004000 adenosine deaminase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005764 lysosome;GO:0009897 external side of plasma membrane;GO:0060205 cytoplasmic vesicle lumen;GO:0070161 anchoring junction", "go_biological_process": "GO:0033081 regulation of T cell differentiation in thymus;GO:0006154 adenosine catabolic process;GO:0009117 nucleotide metabolic process;GO:0046103 inosine biosynthetic process;GO:0042110 T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G8Q3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7G9F9-1", "uniprot_id": [ { "id": "A0A9J7G9F9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7G9F9", "type": "external" } ], "mass": 138409.0, "length": 1256, "protein_name": "Receptor protein-tyrosine kinase", "gene_name": "Erbb2", "organism": "Hamster", "refseq_name": "receptor tyrosine-protein kinase erbB-2 isoform X1", "refseq_ac": [ { "id": "XP_027279946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279946", "type": "external" } ], "gene_names_uniprotkb": "Erbb2", "gene_names_refseq": "Erbb2", "protein_names_uniprotkb": "Receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "receptor tyrosine-protein kinase erbB-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759983)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005769 early endosome;GO:0043209 myelin sheath;GO:0043235 receptor complex;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0051057 positive regulation of small GTPase mediated signal transduction;GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7G9F9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GAS5-1", "uniprot_id": [ { "id": "A0A9J7GAS5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GAS5", "type": "external" } ], "mass": 37265.0, "length": 327, "protein_name": "Interleukin-12 subunit beta", "gene_name": "Il12b", "organism": "Hamster", "refseq_name": "interleukin-12 subunit beta", "refseq_ac": [ { "id": "XP_027280645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280645", "type": "external" } ], "gene_names_uniprotkb": "Il12b; IL12B", "gene_names_refseq": "Il12b", "protein_names_uniprotkb": "Interleukin-12 subunit beta; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12 subunit p40; IL-12B", "protein_names_refseq": "interleukin-12 subunit beta", "tax_id": 10029, "disease": "", "pathway": " (cge:100764758)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis., [UniProtKB, UniProtKB]; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042164 interleukin-12 alpha subunit binding;GO:0005125 cytokine activity;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0070743 interleukin-23 complex;GO:0043514 interleukin-12 complex;GO:0005788 endoplasmic reticulum lumen;GO:0016020 membrane;GO:0031904 endosome lumen", "go_biological_process": "GO:0042110 T cell activation;GO:0050727 regulation of inflammatory response;GO:0002230 positive regulation of defense response to virus by host;GO:0032729 positive regulation of type II interferon production;GO:0042102 positive regulation of T cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GAS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GB29-1", "uniprot_id": [ { "id": "A0A9J7GB29_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GB29", "type": "external" } ], "mass": 51414.0, "length": 444, "protein_name": "Phosphatidate cytidylyltransferase", "gene_name": "Cds2", "organism": "Hamster", "refseq_name": "phosphatidate cytidylyltransferase 2 isoform X1", "refseq_ac": [ { "id": "XP_027277520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277520", "type": "external" } ], "gene_names_uniprotkb": "Cds2", "gene_names_refseq": "Cds2", "protein_names_uniprotkb": "Phosphatidate cytidylyltransferase; 2.7.7.41", "protein_names_refseq": "phosphatidate cytidylyltransferase 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761349)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.41", "type": "external" } ], "go_molecular_function": "GO:0004605 phosphatidate cytidylyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016024 CDP-diacylglycerol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GB29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GBH6-1", "uniprot_id": [ { "id": "A0A9J7GBH6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GBH6", "type": "external" } ], "mass": 532011.0, "length": 4879, "protein_name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "gene_name": "Birc6", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 6 isoform X5", "refseq_ac": [ { "id": "XP_027281881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281881", "type": "external" } ], "gene_names_uniprotkb": "Birc6", "gene_names_refseq": "Birc6", "protein_names_uniprotkb": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6; 2.3.2.24; BIR repeat-containing ubiquitin-conjugating enzyme; Baculoviral IAP repeat-containing protein 6; Ubiquitin-conjugating BIR domain enzyme apollon", "protein_names_refseq": "LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 6 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100689237)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004869 cysteine-type endopeptidase inhibitor activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005813 centrosome", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division;GO:0006915 apoptotic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GBH6-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GCZ7-1", "uniprot_id": [ { "id": "A0A9J7GCZ7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GCZ7", "type": "external" } ], "mass": 116048.0, "length": 1006, "protein_name": "Unconventional myosin-Id", "gene_name": "Myo1d", "organism": "Hamster", "refseq_name": "unconventional myosin-Id isoform X3", "refseq_ac": [ { "id": "XP_027282307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282307", "type": "external" } ], "gene_names_uniprotkb": "Myo1d", "gene_names_refseq": "Myo1d", "protein_names_uniprotkb": "Unconventional myosin-Id", "protein_names_refseq": "unconventional myosin-Id isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773950)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005903 brush border;GO:0005938 cell cortex;GO:0030425 dendrite", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0015031 protein transport;GO:0030048 actin filament-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GCZ7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H3A8-1", "uniprot_id": [ { "id": "A0A9J7H3A8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H3A8", "type": "external" } ], "mass": 84008.0, "length": 757, "protein_name": "Disks large homolog 4", "gene_name": "Dlg4", "organism": "Hamster", "refseq_name": "disks large homolog 4 isoform X2", "refseq_ac": [ { "id": "XP_035304160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304160", "type": "external" } ], "gene_names_uniprotkb": "Dlg4", "gene_names_refseq": "Dlg4", "protein_names_uniprotkb": "Disks large homolog 4; Postsynaptic density protein 95; Synapse-associated protein 90", "protein_names_refseq": "disks large homolog 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762874)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0097110 scaffold protein binding;GO:0035255 ionotropic glutamate receptor binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0016323 basolateral plasma membrane;GO:0031594 neuromuscular junction;GO:0043197 dendritic spine", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0098609 cell-cell adhesion;GO:0048168 regulation of neuronal synaptic plasticity;GO:0060997 dendritic spine morphogenesis;GO:0097113 AMPA glutamate receptor clustering", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H3A8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE04-1", "uniprot_id": [ { "id": "A0A9J7GE04_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE04", "type": "external" } ], "mass": 70610.0, "length": 649, "protein_name": "RING finger protein 112", "gene_name": "Rnf112", "organism": "Hamster", "refseq_name": "RING finger protein 112 isoform X1", "refseq_ac": [ { "id": "XP_027283054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283054", "type": "external" } ], "gene_names_uniprotkb": "Rnf112", "gene_names_refseq": "Rnf112", "protein_names_uniprotkb": "RING finger protein 112; 2.3.2.27; Brain finger protein; Zinc finger protein 179", "protein_names_refseq": "RING finger protein 112 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757943)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005768 endosome;GO:0014069 postsynaptic density;GO:0016020 membrane;GO:0043204 perikaryon;GO:0016604 nuclear body", "go_biological_process": "GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GE78-1", "uniprot_id": [ { "id": "A0A9J7GE78_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GE78", "type": "external" } ], "mass": 21573.0, "length": 194, "protein_name": "Dual specificity protein phosphatase", "gene_name": "Dusp3", "organism": "Hamster", "refseq_name": "dual specificity protein phosphatase 3 isoform X2", "refseq_ac": [ { "id": "XP_027283739", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283739", "type": "external" } ], "gene_names_uniprotkb": "Dusp3", "gene_names_refseq": "Dusp3", "protein_names_uniprotkb": "Dual specificity protein phosphatase; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761077)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027283739.1. COMPLETENESS: full length., [RefSeq]; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate., [UniProtKB, UniProtKB]; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0033549 MAP kinase phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0051893 regulation of focal adhesion assembly;GO:0045931 positive regulation of mitotic cell cycle;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0046329 negative regulation of JNK cascade;GO:0071364 cellular response to epidermal growth factor stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GE78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H626-1", "uniprot_id": [ { "id": "A0A9J7H626_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H626", "type": "external" } ], "mass": 105201.0, "length": 961, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgkq", "organism": "Hamster", "refseq_name": "diacylglycerol kinase theta isoform X2", "refseq_ac": [ { "id": "XP_035303637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303637", "type": "external" } ], "gene_names_uniprotkb": "Dgkq", "gene_names_refseq": "Dgkq", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase theta isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771387)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Within the adrenocorticotropic hormone signaling pathway, produces phosphatidic acid which in turn activates NR5A1 and subsequent steroidogenic gene transcription. Also functions downstream of the nerve growth factor signaling pathway being specifically activated in the nucleus by the growth factor. Through its diacylglycerol activity also regulates synaptic vesicle endocytosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0047649 alkylglycerol kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0016607 nuclear speck;GO:0045202 synapse", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H626-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GHS8-1", "uniprot_id": [ { "id": "A0A9J7GHS8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GHS8", "type": "external" } ], "mass": 98309.0, "length": 888, "protein_name": "Tyrosine-protein kinase receptor UFO", "gene_name": "Axl", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase receptor UFO isoform X2", "refseq_ac": [ { "id": "XP_027286185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286185", "type": "external" } ], "gene_names_uniprotkb": "Axl", "gene_names_refseq": "Axl", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor UFO; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase receptor UFO isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772486)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001779 natural killer cell differentiation;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GHS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GH12-1", "uniprot_id": [ { "id": "A0A9J7GH12_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GH12", "type": "external" } ], "mass": 64563.0, "length": 574, "protein_name": "TNF receptor-associated factor", "gene_name": "Traf4", "organism": "Hamster", "refseq_name": "TNF receptor-associated factor 4 isoform X2", "refseq_ac": [ { "id": "XP_027281915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281915", "type": "external" } ], "gene_names_uniprotkb": "Traf4", "gene_names_refseq": "Traf4", "protein_names_uniprotkb": "TNF receptor-associated factor; 2.3.2.27", "protein_names_refseq": "TNF receptor-associated factor 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762863)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0061630 ubiquitin protein ligase activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0045087 innate immune response;GO:0046330 positive regulation of JNK cascade;GO:0006915 apoptotic process;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GH12-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1H4-1", "uniprot_id": [ { "id": "A0A9J7K1H4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1H4", "type": "external" } ], "mass": 74596.0, "length": 679, "protein_name": "Myotonin-protein kinase", "gene_name": "LOC113837295", "organism": "Hamster", "refseq_name": "myotonin-protein kinase isoform X1", "refseq_ac": [ { "id": "XP_027286745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286745", "type": "external" } ], "gene_names_uniprotkb": "LOC113837295", "gene_names_refseq": "LOC113837295", "protein_names_uniprotkb": "Myotonin-protein kinase; 2.7.11.1; DM-kinase; DMPK; Myotonic dystrophy protein kinase", "protein_names_refseq": "myotonin-protein kinase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:113837295)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0008016 regulation of heart contraction;GO:0031032 actomyosin structure organization;GO:0006998 nuclear envelope organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1H4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GI09-1", "uniprot_id": [ { "id": "A0A9J7GI09_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GI09", "type": "external" } ], "mass": 48139.0, "length": 442, "protein_name": "Sequestosome-1", "gene_name": "Sqstm1", "organism": "Hamster", "refseq_name": "sequestosome-1 isoform X3", "refseq_ac": [ { "id": "XP_027283449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283449", "type": "external" } ], "gene_names_uniprotkb": "Sqstm1", "gene_names_refseq": "Sqstm1", "protein_names_uniprotkb": "Sequestosome-1; Ubiquitin-binding protein p62", "protein_names_refseq": "sequestosome-1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100768352)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0005080 protein kinase C binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005764 lysosome;GO:0005770 late endosome;GO:0030017 sarcomere", "go_biological_process": "GO:0030154 cell differentiation;GO:0006915 apoptotic process;GO:0007032 endosome organization;GO:0000423 mitophagy;GO:0035973 aggrephagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GI09-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GK51-1", "uniprot_id": [ { "id": "A0A9J7GK51_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GK51", "type": "external" } ], "mass": 488930.0, "length": 4447, "protein_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase HUWE1 isoform X1", "refseq_ac": [ { "id": "XP_016830010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830010", "type": "external" } ], "gene_names_uniprotkb": "Huwe1", "gene_names_refseq": "Huwe1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HUWE1; 2.3.2.26; HECT, UBA and WWE domain-containing protein 1; HECT-type E3 ubiquitin transferase HUWE1; Upstream regulatory element-binding protein 1", "protein_names_refseq": "E3 ubiquitin-protein ligase HUWE1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757403)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613780.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0030154 cell differentiation;GO:0006284 base-excision repair;GO:0048511 rhythmic process;GO:0061025 membrane fusion;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GK51-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K242-1", "uniprot_id": [ { "id": "A0A9J7K242_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K242", "type": "external" } ], "mass": 69696.0, "length": 603, "protein_name": "Myotubularin", "gene_name": "LOC100761567", "organism": "Hamster", "refseq_name": "myotubularin isoform X2", "refseq_ac": [ { "id": "XP_027288011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288011", "type": "external" } ], "gene_names_uniprotkb": "LOC100761567", "gene_names_refseq": "LOC100761567", "protein_names_uniprotkb": "Myotubularin; 3.1.3.95; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "myotubularin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761567)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027288011.1. COMPLETENESS: full length., [RefSeq]; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis. In skeletal muscles, stabilizes MTMR12 protein levels., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.64", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" } ], "go_molecular_function": "GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity;GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0012505 endomembrane system;GO:0005886 plasma membrane;GO:0005770 late endosome", "go_biological_process": "GO:1902902 negative regulation of autophagosome assembly;GO:0046716 muscle cell cellular homeostasis;GO:0048311 mitochondrion distribution;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K242-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GKD0-1", "uniprot_id": [ { "id": "A0A9J7GKD0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GKD0", "type": "external" } ], "mass": 75961.0, "length": 663, "protein_name": "Cyclic nucleotide-gated channel alpha-2", "gene_name": "Cnga2", "organism": "Hamster", "refseq_name": "cyclic nucleotide-gated olfactory channel isoform X2", "refseq_ac": [ { "id": "XP_027288054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288054", "type": "external" } ], "gene_names_uniprotkb": "Cnga2", "gene_names_refseq": "Cnga2", "protein_names_uniprotkb": "Cyclic nucleotide-gated channel alpha-2; Olfactory cyclic nucleotide-gated channel subunit 1", "protein_names_refseq": "cyclic nucleotide-gated olfactory channel isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771809)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pore-forming subunit of the olfactory cyclic nucleotide-gated channel. Operates in the cilia of olfactory sensory neurons where chemical stimulation of the odorant is converted to an electrical signal. Mediates odorant-induced cAMP-dependent Ca(2+) influx triggering neuron depolarization. The rise of intracellular Ca(2+) levels potentiates the olfactory response by activating Ca(2+)-dependent Cl(-) channels, but it also serves as a negative feedback signal to desensitize the channel for rapid adaptation to odorants. Conducts cAMP- and cGMP-gated ion currents, with permeability for monovalent and divalent cations., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0005223 intracellularly cGMP-activated cation channel activity;GO:0005222 intracellularly cAMP-activated cation channel activity;GO:0030552 cAMP binding;GO:0030553 cGMP binding", "go_cellular_component": "GO:0060170 ciliary membrane;GO:0017071 intracellular cyclic nucleotide activated cation channel complex", "go_biological_process": "GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GKD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GL59-1", "uniprot_id": [ { "id": "A0A9J7GL59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GL59", "type": "external" } ], "mass": 129159.0, "length": 1129, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp11c", "organism": "Hamster", "refseq_name": "phospholipid-transporting ATPase IG isoform X4", "refseq_ac": [ { "id": "XP_027289215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289215", "type": "external" } ], "gene_names_uniprotkb": "Atp11c", "gene_names_refseq": "Atp11c", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "phospholipid-transporting ATPase IG isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100756336)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of the plasma membrane. Major PS-flippase in immune cell subsets. In erythrocyte plasma membrane, it is required to maintain PS in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for erythrocyte clearance by splenic macrophages. Required for B cell differentiation past the pro-B cell stage. Seems to mediate PS flipping in pro-B cells. May be involved in the transport of cholestatic bile acids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0045332 phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GL59-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2R5-1", "uniprot_id": [ { "id": "A0A9J7K2R5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2R5", "type": "external" } ], "mass": 281194.0, "length": 2488, "protein_name": "Transcriptional regulator ATRX", "gene_name": "Atrx", "organism": "Hamster", "refseq_name": "transcriptional regulator ATRX isoform X2", "refseq_ac": [ { "id": "XP_027288704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288704", "type": "external" } ], "gene_names_uniprotkb": "Atrx", "gene_names_refseq": "Atrx", "protein_names_uniprotkb": "Transcriptional regulator ATRX; 3.6.4.12; ATP-dependent helicase ATRX; X-linked nuclear protein", "protein_names_refseq": "transcriptional regulator ATRX isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767383)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0031490 chromatin DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0016605 PML body;GO:0005721 pericentric heterochromatin;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0033044 regulation of chromosome organization;GO:0031509 subtelomeric heterochromatin formation;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2R5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLQ8-1", "uniprot_id": [ { "id": "A0A9J7GLQ8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLQ8", "type": "external" } ], "mass": 99461.0, "length": 903, "protein_name": "Amine oxidase", "gene_name": "LOC100760815", "organism": "Hamster", "refseq_name": "amine oxidase [flavin-containing] A", "refseq_ac": [ { "id": "XP_003510347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510347", "type": "external" } ], "gene_names_uniprotkb": "LOC100760815", "gene_names_refseq": "LOC100760815", "protein_names_uniprotkb": "Amine oxidase; 1.4.3.-", "protein_names_refseq": "amine oxidase [flavin-containing] A", "tax_id": 10029, "disease": "", "pathway": " (cge:100760815)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614857.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003510347.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" } ], "go_molecular_function": "GO:0097621 monoamine oxidase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008131 primary methylamine oxidase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006584 catecholamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GLR3-1", "uniprot_id": [ { "id": "A0A9J7GLR3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GLR3", "type": "external" } ], "mass": 144153.0, "length": 1262, "protein_name": "Arylsulfatase", "gene_name": "Sulf1", "organism": "Hamster", "refseq_name": "extracellular sulfatase Sulf-1 isoform X2", "refseq_ac": [ { "id": "XP_035294599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294599", "type": "external" } ], "gene_names_uniprotkb": "Sulf1", "gene_names_refseq": "Sulf1", "protein_names_uniprotkb": "Arylsulfatase; 3.1.6.14; 3.1.6.1; N-acetylglucosamine-6-sulfatase", "protein_names_refseq": "extracellular sulfatase Sulf-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764289)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 30% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.6.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.1", "type": "external" }, { "id": "3.1.6.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.15", "type": "external" }, { "id": "3.1.6.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.18", "type": "external" }, { "id": "3.1.6.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.14", "type": "external" }, { "id": "3.1.6.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.-", "type": "external" } ], "go_molecular_function": "GO:0008449 N-acetylglucosamine-6-sulfatase activity;GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity;GO:0005539 glycosaminoglycan binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005795 Golgi stack", "go_biological_process": "GO:0030201 heparan sulfate proteoglycan metabolic process;GO:0010575 positive regulation of vascular endothelial growth factor production;GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway;GO:0030177 positive regulation of Wnt signaling pathway;GO:0032836 glomerular basement membrane development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GLR3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQ04-1", "uniprot_id": [ { "id": "A0A9J7GQ04_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQ04", "type": "external" } ], "mass": 56071.0, "length": 494, "protein_name": "Endothelial lipase", "gene_name": "Lipg", "organism": "Hamster", "refseq_name": "endothelial lipase", "refseq_ac": [ { "id": "XP_035294605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294605", "type": "external" } ], "gene_names_uniprotkb": "Lipg", "gene_names_refseq": "Lipg", "protein_names_uniprotkb": "Endothelial lipase; 3.1.1.32; 3.1.1.3; Phospholipase A1", "protein_names_refseq": "endothelial lipase", "tax_id": 10029, "disease": "", "pathway": " (cge:100766418)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Exerts both phospholipase and triglyceride lipase activities. More active as a phospholipase than a triglyceride lipase. Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.116", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.116", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "3.1.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.34", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" }, { "id": "3.1.1.79", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.79", "type": "external" }, { "id": "3.1.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.6", "type": "external" } ], "go_molecular_function": "GO:0008201 heparin binding;GO:0046872 metal ion binding;GO:0008970 phospholipase A1 activity;GO:0004465 lipoprotein lipase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQ04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GQS6-1", "uniprot_id": [ { "id": "A0A9J7GQS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GQS6", "type": "external" } ], "mass": 32978.0, "length": 297, "protein_name": "Small ribosomal subunit protein uS2", "gene_name": "LOC100751634", "organism": "Hamster", "refseq_name": "40S ribosomal protein SA-like isoform X2", "refseq_ac": [ { "id": "XP_035296469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296469", "type": "external" } ], "gene_names_uniprotkb": "LOC100751634; RPSA", "gene_names_refseq": "LOC100751634", "protein_names_uniprotkb": "Small ribosomal subunit protein uS2; 37 kDa laminin receptor precursor; 37/67 kDa laminin receptor; 37LRP; 67 kDa laminin receptor; 67LR; LBP/p40; LRP/LR; LamR; Laminin receptor 1; Laminin-binding protein precursor p40", "protein_names_refseq": "40S ribosomal protein SA-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751634)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043236 laminin binding;GO:0005055 laminin receptor activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GQS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GRL5-1", "uniprot_id": [ { "id": "A0A9J7GRL5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GRL5", "type": "external" } ], "mass": 687356.0, "length": 6282, "protein_name": "Adhesion G-protein coupled receptor V1", "gene_name": "Adgrv1", "organism": "Hamster", "refseq_name": "adhesion G-protein coupled receptor V1 isoform X3", "refseq_ac": [ { "id": "XP_035296369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296369", "type": "external" } ], "gene_names_uniprotkb": "Adgrv1", "gene_names_refseq": "Adgrv1", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor V1; G-protein coupled receptor 98; Very large G-protein coupled receptor 1", "protein_names_refseq": "adhesion G-protein coupled receptor V1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100766602)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaved ADGRV1 beta-subunit couples with G-alpha(i)-proteins, GNAI1/2/3, and constitutively inhibits adenylate cyclase (AC) activity with a stronger effect than full ADGRV1., [UniProtKB, UniProtKB]; G-protein coupled receptor which has an essential role in the development of hearing and vision. Couples to G-alpha(i)-proteins, GNAI1/2/3, G-alpha(q)-proteins, GNAQ, as well as G-alpha(s)-proteins, GNAS, inhibiting adenylate cyclase (AC) activity and cAMP production. Required for the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells of the inner ear. In response to extracellular calcium, activates kinases PKA and PKC to regulate myelination by inhibiting the ubiquitination of MAG, thus enhancing the stability of this protein in myelin-forming cells of the auditory pathway. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport. Involved in the regulation of bone metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0016787 hydrolase activity;GO:0001965 G-protein alpha-subunit binding;GO:0010855 adenylate cyclase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001917 photoreceptor inner segment;GO:0032991 protein-containing complex;GO:0060171 stereocilium membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0007166 cell surface receptor signaling pathway;GO:0071277 cellular response to calcium ion;GO:0007601 visual perception;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GRL5-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GSB4-1", "uniprot_id": [ { "id": "A0A9J7GSB4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GSB4", "type": "external" } ], "mass": 321444.0, "length": 2893, "protein_name": "Teneurin-4", "gene_name": "Tenm4", "organism": "Hamster", "refseq_name": "teneurin-4 isoform X2", "refseq_ac": [ { "id": "XP_035298282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298282", "type": "external" } ], "gene_names_uniprotkb": "Tenm4", "gene_names_refseq": "Tenm4", "protein_names_uniprotkb": "Teneurin-4; Protein Odd Oz/ten-m homolog 4; Tenascin-M4; Teneurin transmembrane protein 4", "protein_names_refseq": "teneurin-4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767886)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0032289 central nervous system myelin formation;GO:0007165 signal transduction;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0031641 regulation of myelination;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GSB4-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GSH7-1", "uniprot_id": [ { "id": "A0A9J7GSH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GSH7", "type": "external" } ], "mass": 51677.0, "length": 478, "protein_name": "Sialidase-4", "gene_name": "Neu4", "organism": "Hamster", "refseq_name": "sialidase-4", "refseq_ac": [ { "id": "XP_035295185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295185", "type": "external" } ], "gene_names_uniprotkb": "Neu4", "gene_names_refseq": "Neu4", "protein_names_uniprotkb": "Sialidase-4; 3.2.1.18; N-acetyl-alpha-neuraminidase 4", "protein_names_refseq": "sialidase-4", "tax_id": 10029, "disease": "", "pathway": " (cge:100774175)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Efficiently hydrolyzes gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3. Hydrolyzes poly-alpha-(2->8)-sialylated neural cell adhesion molecule NCAM1 likely at growth cones, suppressing neurite outgrowth in hippocampal neurons. May desialylate sialyl Lewis A and X antigens at the cell surface, down-regulating these glycan epitopes recognized by SELE/E selectin in the initiation of cell adhesion and extravasation. Has sialidase activity toward mucin, fetuin and sialyllactose., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.18", "type": "external" } ], "go_molecular_function": "GO:0004308 exo-alpha-sialidase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0009313 oligosaccharide catabolic process;GO:0006516 glycoprotein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GSH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GUI7-1", "uniprot_id": [ { "id": "A0A9J7GUI7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GUI7", "type": "external" } ], "mass": 248456.0, "length": 2212, "protein_name": "Supervillin", "gene_name": "Svil", "organism": "Hamster", "refseq_name": "supervillin isoform X1", "refseq_ac": [ { "id": "XP_035298668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298668", "type": "external" } ], "gene_names_uniprotkb": "Svil", "gene_names_refseq": "Svil", "protein_names_uniprotkb": "Supervillin; Archvillin; p205/p250", "protein_names_refseq": "supervillin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762636)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. In addition to its cytoskeletal activities, acts as a cofactor or scaffold for KDM1A, facilitating H3K9me2 demethylation and promoting gene activation, especially in neuronal contexts., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; May be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0002102 podosome;GO:0032154 cleavage furrow;GO:0030496 midbody;GO:0042995 cell projection", "go_biological_process": "GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:0061061 muscle structure development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GUI7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GT55-1", "uniprot_id": [ { "id": "A0A9J7GT55_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GT55", "type": "external" } ], "mass": 54737.0, "length": 492, "protein_name": "Cholesteryl ester transfer protein", "gene_name": "Cetp", "organism": "Hamster", "refseq_name": "cholesteryl ester transfer protein isoform X1", "refseq_ac": [ { "id": "XP_035297308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297308", "type": "external" } ], "gene_names_uniprotkb": "Cetp", "gene_names_refseq": "Cetp", "protein_names_uniprotkb": "Cholesteryl ester transfer protein", "protein_names_refseq": "cholesteryl ester transfer protein isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758852)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005548 phospholipid transporter activity;GO:0015485 cholesterol binding;GO:0031210 phosphatidylcholine binding;GO:0017129 triglyceride binding;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0034364 high-density lipoprotein particle", "go_biological_process": "GO:0006641 triglyceride metabolic process;GO:0008203 cholesterol metabolic process;GO:0034374 low-density lipoprotein particle remodeling;GO:0034375 high-density lipoprotein particle remodeling;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GT55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GT78-1", "uniprot_id": [ { "id": "A0A9J7GT78_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GT78", "type": "external" } ], "mass": 35852.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC100757828", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase-like", "refseq_ac": [ { "id": "XP_035298346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298346", "type": "external" } ], "gene_names_uniprotkb": "LOC100757828", "gene_names_refseq": "LOC100757828", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100757828)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GT78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GUB9-1", "uniprot_id": [ { "id": "A0A9J7GUB9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GUB9", "type": "external" } ], "mass": 55155.0, "length": 482, "protein_name": "Histone deacetylase 1", "gene_name": "LOC100761556", "organism": "Hamster", "refseq_name": "histone deacetylase 1-like", "refseq_ac": [ { "id": "XP_035298589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298589", "type": "external" } ], "gene_names_uniprotkb": "LOC100761556", "gene_names_refseq": "LOC100761556", "protein_names_uniprotkb": "Histone deacetylase 1; 3.5.1.98; HD1", "protein_names_refseq": "histone deacetylase 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100761556)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" } ], "go_molecular_function": "GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:0140297 DNA-binding transcription factor binding;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016581 NuRD complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GUB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GVQ2-1", "uniprot_id": [ { "id": "A0A9J7GVQ2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GVQ2", "type": "external" } ], "mass": 94150.0, "length": 840, "protein_name": "Fibroblast growth factor receptor", "gene_name": "Fgfr2", "organism": "Hamster", "refseq_name": "fibroblast growth factor receptor 2 isoform X4", "refseq_ac": [ { "id": "XP_035298055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298055", "type": "external" } ], "gene_names_uniprotkb": "Fgfr2", "gene_names_refseq": "Fgfr2", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "fibroblast growth factor receptor 2 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100763455)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0008284 positive regulation of cell population proliferation;GO:0006915 apoptotic process;GO:0050680 negative regulation of epithelial cell proliferation;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GVQ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GUH4-1", "uniprot_id": [ { "id": "A0A9J7GUH4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GUH4", "type": "external" } ], "mass": 89611.0, "length": 852, "protein_name": "Cadherin-related family member 5", "gene_name": "Cdhr5", "organism": "Hamster", "refseq_name": "cadherin-related family member 5 isoform X2", "refseq_ac": [ { "id": "XP_035298007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298007", "type": "external" } ], "gene_names_uniprotkb": "Cdhr5", "gene_names_refseq": "Cdhr5", "protein_names_uniprotkb": "Cadherin-related family member 5; Mu-protocadherin", "protein_names_refseq": "cadherin-related family member 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756177)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0016342 catenin complex;GO:0031528 microvillus membrane", "go_biological_process": "GO:0016477 cell migration;GO:0030154 cell differentiation;GO:0000902 cell morphogenesis;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GUH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GWA9-1", "uniprot_id": [ { "id": "A0A9J7GWA9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GWA9", "type": "external" } ], "mass": 80324.0, "length": 728, "protein_name": "Synaptotagmin-7", "gene_name": "Syt7", "organism": "Hamster", "refseq_name": "synaptotagmin-7 isoform X2", "refseq_ac": [ { "id": "XP_035297476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297476", "type": "external" } ], "gene_names_uniprotkb": "Syt7", "gene_names_refseq": "Syt7", "protein_names_uniprotkb": "Synaptotagmin-7; Synaptotagmin VII", "protein_names_refseq": "synaptotagmin-7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771245)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0030276 clathrin binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0030424 axon;GO:0005765 lysosomal membrane;GO:0030670 phagocytic vesicle membrane;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0030100 regulation of endocytosis;GO:0050796 regulation of insulin secretion;GO:0017158 regulation of calcium ion-dependent exocytosis;GO:0048791 calcium ion-regulated exocytosis of neurotransmitter", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GWA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GX29-1", "uniprot_id": [ { "id": "A0A9J7GX29_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GX29", "type": "external" } ], "mass": 25229.0, "length": 240, "protein_name": "Neuromodulin", "gene_name": "Gap43", "organism": "Hamster", "refseq_name": "neuromodulin", "refseq_ac": [ { "id": "XP_035300246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300246", "type": "external" } ], "gene_names_uniprotkb": "Gap43", "gene_names_refseq": "Gap43", "protein_names_uniprotkb": "Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43", "protein_names_refseq": "neuromodulin", "tax_id": 10029, "disease": "", "pathway": " (cge:100751655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0001786 phosphatidylserine binding;GO:1901981 phosphatidylinositol phosphate binding;GO:0035727 lysophosphatidic acid binding", "go_cellular_component": "GO:0032584 growth cone membrane;GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0043204 perikaryon", "go_biological_process": "GO:0016198 axon choice point recognition;GO:0040008 regulation of growth;GO:0042246 tissue regeneration;GO:0031103 axon regeneration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GX29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GXT4-1", "uniprot_id": [ { "id": "A0A9J7GXT4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GXT4", "type": "external" } ], "mass": 68294.0, "length": 642, "protein_name": "Tumor necrosis factor receptor superfamily member 5", "gene_name": "Tnfrsf11a", "organism": "Hamster", "refseq_name": "tumor necrosis factor receptor superfamily member 11A isoform X2", "refseq_ac": [ { "id": "XP_035301729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301729", "type": "external" } ], "gene_names_uniprotkb": "Tnfrsf11a", "gene_names_refseq": "Tnfrsf11a", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; CD40L receptor", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 11A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753416)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005031 tumor necrosis factor receptor activity;GO:0019955 cytokine binding", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0023035 CD40 signaling pathway;GO:0006952 defense response;GO:0006874 intracellular calcium ion homeostasis;GO:0045780 positive regulation of bone resorption", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GXT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7GZK0-1", "uniprot_id": [ { "id": "A0A9J7GZK0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7GZK0", "type": "external" } ], "mass": 139025.0, "length": 1233, "protein_name": "Receptor-type tyrosine-protein phosphatase C", "gene_name": "Ptprc", "organism": "Hamster", "refseq_name": "receptor-type tyrosine-protein phosphatase C isoform X2", "refseq_ac": [ { "id": "XP_035301719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301719", "type": "external" } ], "gene_names_uniprotkb": "Ptprc", "gene_names_refseq": "Ptprc", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase C; 3.1.3.48; Leukocyte common antigen; T200", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase C isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761948)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. Interacts with CLEC10A at antigen presenting cell-T cell contact; CLEC10A on immature dendritic cells recognizes Tn antigen-carrying PTPRC/CD45 receptor on effector T cells and modulates T cell activation threshold to limit autoreactivity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft;GO:0045202 synapse;GO:0098552 side of membrane", "go_biological_process": "GO:0050852 T cell receptor signaling pathway;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7GZK0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H1K5-1", "uniprot_id": [ { "id": "A0A9J7H1K5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H1K5", "type": "external" } ], "mass": 107191.0, "length": 979, "protein_name": "ATP-dependent DNA helicase", "gene_name": "LOC100755041", "organism": "Hamster", "refseq_name": "ATP-dependent DNA helicase Q5 isoform X2", "refseq_ac": [ { "id": "XP_007641522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641522", "type": "external" } ], "gene_names_uniprotkb": "LOC100755041", "gene_names_refseq": "LOC100755041", "protein_names_uniprotkb": "ATP-dependent DNA helicase; 5.6.2.4", "protein_names_refseq": "ATP-dependent DNA helicase Q5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755041)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1546 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613598.1) and transcript sequence (IACG01201828.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007641522.3. COMPLETENESS: full length., [RefSeq]; DNA helicase that plays an important role in DNA replication, transcription and repair. Binds to the RNA polymerase II subunit POLR2A during transcription elongation and suppresses transcription-associated genomic instability. Also associates with POLR1A and enforces the stability of ribosomal DNA arrays. Plays an important role in mitotic chromosome separation after cross-over events and cell cycle progress. Mechanistically, removes RAD51 filaments protecting stalled replication forks at common fragile sites and stimulates MUS81-EME1 endonuclease leading to mitotic DNA synthesis. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0051301 cell division;GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination;GO:0010605 negative regulation of macromolecule metabolic process;GO:0045934 negative regulation of nucleobase-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H1K5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H2T6-1", "uniprot_id": [ { "id": "A0A9J7H2T6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H2T6", "type": "external" } ], "mass": 2983879.0, "length": 26855, "protein_name": "Titin", "gene_name": "Ttn", "organism": "Hamster", "refseq_name": "titin isoform X3", "refseq_ac": [ { "id": "XP_035302231", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302231", "type": "external" } ], "gene_names_uniprotkb": "Ttn", "gene_names_refseq": "Ttn", "protein_names_uniprotkb": "Titin; 2.7.11.1; Connectin", "protein_names_refseq": "titin isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100767264)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase., [UniProtKB, UniProtKB]", "predicted_glycosites": 14, "predicted_n_glycosites": 0, "predicted_o_glycosites": 14, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0031674 I band;GO:0015629 actin cytoskeleton;GO:0030018 Z disc;GO:0031430 M band", "go_biological_process": "GO:0003007 heart morphogenesis;GO:0055013 cardiac muscle cell development;GO:0045989 positive regulation of striated muscle contraction;GO:0060298 positive regulation of sarcomere organization;GO:0006936 muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H2T6-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H0Q2-1", "uniprot_id": [ { "id": "A0A9J7H0Q2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H0Q2", "type": "external" } ], "mass": 52706.0, "length": 467, "protein_name": "Kynureninase", "gene_name": "LOC100771448", "organism": "Hamster", "refseq_name": "kynureninase isoform X3", "refseq_ac": [ { "id": "XP_035302713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302713", "type": "external" } ], "gene_names_uniprotkb": "LOC100771448; KYNU", "gene_names_refseq": "LOC100771448", "protein_names_uniprotkb": "Kynureninase; 3.7.1.3; L-kynurenine hydrolase", "protein_names_refseq": "kynureninase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100771448)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.7.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.7.1.3", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0030429 kynureninase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0097053 L-kynurenine catabolic process;GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0019805 quinolinate biosynthetic process;GO:0043420 anthranilate metabolic process;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H0Q2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H0T8-1", "uniprot_id": [ { "id": "A0A9J7H0T8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H0T8", "type": "external" } ], "mass": 50026.0, "length": 428, "protein_name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "gene_name": "LOC100752606", "organism": "Hamster", "refseq_name": "cholesterol side-chain cleavage enzyme, mitochondrial", "refseq_ac": [ { "id": "XP_035300291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300291", "type": "external" } ], "gene_names_uniprotkb": "LOC100752606", "gene_names_refseq": "LOC100752606", "protein_names_uniprotkb": "Cholesterol side-chain cleavage enzyme, mitochondrial; 1.14.15.6; Cholesterol desmolase", "protein_names_refseq": "cholesterol side-chain cleavage enzyme, mitochondrial", "tax_id": 10029, "disease": "", "pathway": " (cge:100752606)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.15.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.6", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0006700 C21-steroid hormone biosynthetic process;GO:0006704 glucocorticoid biosynthetic process;GO:0071375 cellular response to peptide hormone stimulus;GO:0034650 cortisol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H0T8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H3M5-1", "uniprot_id": [ { "id": "A0A9J7H3M5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H3M5", "type": "external" } ], "mass": 148122.0, "length": 1305, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Myo3b", "organism": "Hamster", "refseq_name": "myosin-IIIb", "refseq_ac": [ { "id": "XP_035302398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302398", "type": "external" } ], "gene_names_uniprotkb": "Myo3b", "gene_names_refseq": "Myo3b", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "myosin-IIIb", "tax_id": 10029, "disease": "", "pathway": " (cge:100772899)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001917 photoreceptor inner segment;GO:0032433 filopodium tip;GO:0032426 stereocilium tip;GO:0016459 myosin complex", "go_biological_process": "GO:0030832 regulation of actin filament length;GO:0007601 visual perception;GO:0007605 sensory perception of sound;GO:0051491 positive regulation of filopodium assembly;GO:0060088 auditory receptor cell stereocilium organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H3M5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H3N1-1", "uniprot_id": [ { "id": "A0A9J7H3N1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H3N1", "type": "external" } ], "mass": 876541.0, "length": 8035, "protein_name": "Obscurin", "gene_name": "Obscn", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: obscurin isoform X2", "refseq_ac": [ { "id": "XP_035304166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304166", "type": "external" } ], "gene_names_uniprotkb": "Obscn", "gene_names_refseq": "Obscn", "protein_names_uniprotkb": "Obscurin; 2.7.11.1; Obscurin-RhoGEF; Obscurin-myosin light chain kinase", "protein_names_refseq": "LOW QUALITY PROTEIN: obscurin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763304)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels internal stop codons :: corrected 1 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Structural component of striated muscles which plays a role in myofibrillogenesis. Probably involved in the assembly of myosin into sarcomeric A bands in striated muscle. Has serine/threonine protein kinase activity and phosphorylates N-cadherin CDH2 and sodium/potassium-transporting ATPase subunit ATP1B1. Binds (via the PH domain) strongly to phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), and to a lesser extent to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 5-phosphate (PtdIns(5)P) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3)., [UniProtKB, UniProtKB]", "predicted_glycosites": 11, "predicted_n_glycosites": 0, "predicted_o_glycosites": 11, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0042383 sarcolemma;GO:0030018 Z disc;GO:0031430 M band", "go_biological_process": "GO:0030154 cell differentiation;GO:1902531 regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H3N1-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H436-1", "uniprot_id": [ { "id": "A0A9J7H436_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H436", "type": "external" } ], "mass": 53603.0, "length": 461, "protein_name": "Phosphatidylserine synthase", "gene_name": "LOC100763873", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: phosphatidylserine synthase 2 isoform X2", "refseq_ac": [ { "id": "XP_035303437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303437", "type": "external" } ], "gene_names_uniprotkb": "LOC100763873", "gene_names_refseq": "LOC100763873", "protein_names_uniprotkb": "Phosphatidylserine synthase; 2.7.8.29; Serine-exchange enzyme", "protein_names_refseq": "LOW QUALITY PROTEIN: phosphatidylserine synthase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763873)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.8.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.29", "type": "external" } ], "go_molecular_function": "GO:0106245 L-serine-phosphatidylethanolamine phosphatidyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006659 phosphatidylserine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H436-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H4F0-1", "uniprot_id": [ { "id": "A0A9J7H4F0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H4F0", "type": "external" } ], "mass": 35794.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC100766073", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase-like", "refseq_ac": [ { "id": "XP_035302611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302611", "type": "external" } ], "gene_names_uniprotkb": "LOC100766073", "gene_names_refseq": "LOC100766073", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100766073)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H4F0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H7M1-1", "uniprot_id": [ { "id": "A0A9J7H7M1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H7M1", "type": "external" } ], "mass": 303279.0, "length": 2733, "protein_name": "Teneurin-2", "gene_name": "LOC113836627", "organism": "Hamster", "refseq_name": "teneurin-2 isoform X2", "refseq_ac": [ { "id": "XP_035304084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304084", "type": "external" } ], "gene_names_uniprotkb": "LOC113836627", "gene_names_refseq": "LOC113836627", "protein_names_uniprotkb": "Teneurin-2; Protein Odd Oz/ten-m homolog 2; Tenascin-M2; Teneurin transmembrane protein 2", "protein_names_refseq": "teneurin-2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113836627)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Induces gene transcription inhibition., [UniProtKB, UniProtKB, UniProtKB]; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Acts as a ligand of the ADGRL1 and ADGRL3 receptors that are expressed at the surface of adjacent cells. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Mediates axon guidance and homophilic and heterophilic cell-cell adhesion. May function as a cellular signal transducer., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0050839 cell adhesion molecule binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030426 growth cone;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007165 signal transduction;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H7M1-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H4V0-1", "uniprot_id": [ { "id": "A0A9J7H4V0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H4V0", "type": "external" } ], "mass": 165416.0, "length": 1464, "protein_name": "Glutamate receptor", "gene_name": "Grin2a", "organism": "Hamster", "refseq_name": "glutamate receptor ionotropic, NMDA 2A isoform X1", "refseq_ac": [ { "id": "XP_035303855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303855", "type": "external" } ], "gene_names_uniprotkb": "Grin2a", "gene_names_refseq": "Grin2a", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, NMDA 2A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764315)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005261 monoatomic cation channel activity;GO:0004972 NMDA glutamate receptor activity", "go_cellular_component": "GO:0017146 NMDA selective glutamate receptor complex;GO:0005783 endoplasmic reticulum;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0008306 associative learning;GO:0045471 response to ethanol;GO:0060079 excitatory postsynaptic potential;GO:0009410 response to xenobiotic stimulus;GO:0060291 long-term synaptic potentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H4V0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H5J9-1", "uniprot_id": [ { "id": "A0A9J7H5J9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H5J9", "type": "external" } ], "mass": 101945.0, "length": 903, "protein_name": "Adenylate cyclase type 3", "gene_name": "Adcy3", "organism": "Hamster", "refseq_name": "adenylate cyclase type 3", "refseq_ac": [ { "id": "XP_035303519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303519", "type": "external" } ], "gene_names_uniprotkb": "Adcy3", "gene_names_refseq": "Adcy3", "protein_names_uniprotkb": "Adenylate cyclase type 3; 4.6.1.1; ATP pyrophosphate-lyase 3; Adenylate cyclase type III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3", "protein_names_refseq": "adenylate cyclase type 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770498)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis: specifically activated by G alpha protein GNAL/G(olf) in olfactory epithelium. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0060170 ciliary membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:1904322 cellular response to forskolin;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H5J9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H661-1", "uniprot_id": [ { "id": "A0A9J7H661_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H661", "type": "external" } ], "mass": 76044.0, "length": 663, "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX12 isoform X4", "gene_name": "Alox12", "organism": "Hamster", "refseq_name": "polyunsaturated fatty acid lipoxygenase ALOX12 isoform X4", "refseq_ac": [ { "id": "XP_035303702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303702", "type": "external" } ], "gene_names_uniprotkb": "Alox12", "gene_names_refseq": "Alox12", "protein_names_uniprotkb": "Polyunsaturated fatty acid lipoxygenase ALOX12 isoform X4", "protein_names_refseq": "polyunsaturated fatty acid lipoxygenase ALOX12 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100764620)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0004052 arachidonate 12(S)-lipoxygenase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0034440 lipid oxidation;GO:0019372 lipoxygenase pathway;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H661-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JY82-1", "uniprot_id": [ { "id": "A0A9J7JY82_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JY82", "type": "external" } ], "mass": 50885.0, "length": 463, "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "Tnfrsf1a", "organism": "Hamster", "refseq_name": "tumor necrosis factor receptor superfamily member 1A isoform X2", "refseq_ac": [ { "id": "XP_027284127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284127", "type": "external" } ], "gene_names_uniprotkb": "Tnfrsf1a", "gene_names_refseq": "Tnfrsf1a", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type I; p55; p60", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 1A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765017)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043120 tumor necrosis factor binding;GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0006954 inflammatory response;GO:0006915 apoptotic process;GO:0006693 prostaglandin metabolic process;GO:0050793 regulation of developmental process;GO:0010557 positive regulation of macromolecule biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JY82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JSW6-1", "uniprot_id": [ { "id": "A0A9J7JSW6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JSW6", "type": "external" } ], "mass": 161868.0, "length": 1491, "protein_name": "Copper-transporting ATPase 1", "gene_name": "Atp7a", "organism": "Hamster", "refseq_name": "copper-transporting ATPase 1 isoform X1", "refseq_ac": [ { "id": "XP_027288679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288679", "type": "external" } ], "gene_names_uniprotkb": "Atp7a", "gene_names_refseq": "Atp7a", "protein_names_uniprotkb": "Copper-transporting ATPase 1; 7.2.2.8; Copper pump 1; Menkes disease-associated protein homolog", "protein_names_refseq": "copper-transporting ATPase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689242)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.2.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0005507 copper ion binding;GO:0140581 P-type monovalent copper transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0030424 axon;GO:0030425 dendrite;GO:0032588 trans-Golgi network membrane", "go_biological_process": "GO:0006878 intracellular copper ion homeostasis;GO:0060003 copper ion export;GO:0010038 response to metal ion;GO:0046688 response to copper ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JSW6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H847-1", "uniprot_id": [ { "id": "A0A9J7H847_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H847", "type": "external" } ], "mass": 123686.0, "length": 1114, "protein_name": "Tyrosine-protein kinase", "gene_name": "Jak3", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase JAK3 isoform X2", "refseq_ac": [ { "id": "XP_035306285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306285", "type": "external" } ], "gene_names_uniprotkb": "Jak3", "gene_names_refseq": "Jak3", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase JAK3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773497)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 499 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) and transcript sequence (IACG01016440.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0005131 growth hormone receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0045087 innate immune response;GO:0002250 adaptive immune response;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H847-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H8L4-1", "uniprot_id": [ { "id": "A0A9J7H8L4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H8L4", "type": "external" } ], "mass": 91963.0, "length": 839, "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "Irak1", "organism": "Hamster", "refseq_name": "interleukin-1 receptor-associated kinase 1 isoform X6", "refseq_ac": [ { "id": "XP_035305993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305993", "type": "external" } ], "gene_names_uniprotkb": "Irak1", "gene_names_refseq": "Irak1", "protein_names_uniprotkb": "Interleukin-1 receptor-associated kinase 1; 2.7.11.1", "protein_names_refseq": "interleukin-1 receptor-associated kinase 1 isoform X6", "tax_id": 10029, "disease": "", "pathway": " (cge:100773909)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0045087 innate immune response;GO:0006355 regulation of DNA-templated transcription;GO:0031663 lipopolysaccharide-mediated signaling pathway;GO:1902533 positive regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H8L4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H8Z0-1", "uniprot_id": [ { "id": "A0A9J7H8Z0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H8Z0", "type": "external" } ], "mass": 58362.0, "length": 513, "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "LOC100761443", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168-like", "refseq_ac": [ { "id": "XP_035306199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306199", "type": "external" } ], "gene_names_uniprotkb": "LOC100761443; RNF168", "gene_names_refseq": "LOC100761443", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF168; 2.3.2.27; RING finger protein 168; RING-type E3 ubiquitin transferase RNF168", "protein_names_refseq": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100761443)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding;GO:0043130 ubiquitin binding;GO:0031491 nucleosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0006302 double-strand break repair;GO:0010212 response to ionizing radiation;GO:0045739 positive regulation of DNA repair;GO:0016567 protein ubiquitination;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H8Z0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H920-1", "uniprot_id": [ { "id": "A0A9J7H920_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H920", "type": "external" } ], "mass": 26377.0, "length": 239, "protein_name": "Triggering receptor expressed on myeloid cells 2", "gene_name": "Trem2", "organism": "Hamster", "refseq_name": "triggering receptor expressed on myeloid cells 2", "refseq_ac": [ { "id": "XP_035292377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292377", "type": "external" } ], "gene_names_uniprotkb": "Trem2", "gene_names_refseq": "Trem2", "protein_names_uniprotkb": "Triggering receptor expressed on myeloid cells 2; Triggering receptor expressed on monocytes 2", "protein_names_refseq": "triggering receptor expressed on myeloid cells 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757821)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 8% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615227.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0008289 lipid binding;GO:0097367 carbohydrate derivative binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:1904141 positive regulation of microglial cell migration;GO:1904951 positive regulation of establishment of protein localization;GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H920-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H9K9-1", "uniprot_id": [ { "id": "A0A9J7H9K9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H9K9", "type": "external" } ], "mass": 155496.0, "length": 1411, "protein_name": "Receptor protein-tyrosine kinase", "gene_name": "Erbb3", "organism": "Hamster", "refseq_name": "receptor tyrosine-protein kinase erbB-3 isoform X2", "refseq_ac": [ { "id": "XP_035307246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307246", "type": "external" } ], "gene_names_uniprotkb": "Erbb3", "gene_names_refseq": "Erbb3", "protein_names_uniprotkb": "Receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "receptor tyrosine-protein kinase erbB-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767681)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0038131 neuregulin receptor activity;GO:0038132 neuregulin binding;GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0038127 ERBB signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0022008 neurogenesis;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H9K9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7H9R9-1", "uniprot_id": [ { "id": "A0A9J7H9R9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7H9R9", "type": "external" } ], "mass": 64901.0, "length": 592, "protein_name": "Solute carrier family 22 member 7", "gene_name": "Slc22a7", "organism": "Hamster", "refseq_name": "solute carrier family 22 member 7", "refseq_ac": [ { "id": "XP_035307360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307360", "type": "external" } ], "gene_names_uniprotkb": "Slc22a7", "gene_names_refseq": "Slc22a7", "protein_names_uniprotkb": "Solute carrier family 22 member 7; Organic anion transporter 2", "protein_names_refseq": "solute carrier family 22 member 7", "tax_id": 10029, "disease": "", "pathway": " (cge:100757046)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 8% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015132 prostaglandin transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7H9R9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HAH3-1", "uniprot_id": [ { "id": "A0A9J7HAH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HAH3", "type": "external" } ], "mass": 122453.0, "length": 1073, "protein_name": "Ceruloplasmin", "gene_name": "Cp", "organism": "Hamster", "refseq_name": "ceruloplasmin", "refseq_ac": [ { "id": "XP_035306928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306928", "type": "external" } ], "gene_names_uniprotkb": "Cp", "gene_names_refseq": "Cp", "protein_names_uniprotkb": "Ceruloplasmin; 1.11.1.27; 1.11.1.9; 1.16.3.1; 1.16.3.4; Cuproxidase ceruloplasmin; Ferroxidase ceruloplasmin; Glutathione peroxidase ceruloplasmin; Glutathione-dependent peroxiredoxin ceruloplasmin", "protein_names_refseq": "ceruloplasmin", "tax_id": 10029, "disease": "", "pathway": " (cge:100753849)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols. Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "1.16.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.4", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004322 ferroxidase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HAH3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HAN8-1", "uniprot_id": [ { "id": "A0A9J7HAN8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HAN8", "type": "external" } ], "mass": 38308.0, "length": 355, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC100759100", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase isoform X2", "refseq_ac": [ { "id": "XP_035307189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307189", "type": "external" } ], "gene_names_uniprotkb": "LOC100759100", "gene_names_refseq": "LOC100759100", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759100)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006006 glucose metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HAN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HC19-1", "uniprot_id": [ { "id": "A0A9J7HC19_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HC19", "type": "external" } ], "mass": 122096.0, "length": 1067, "protein_name": "Thyrotropin-releasing hormone-degrading ectoenzyme", "gene_name": "Trhde", "organism": "Hamster", "refseq_name": "thyrotropin-releasing hormone-degrading ectoenzyme isoform X2", "refseq_ac": [ { "id": "XP_035307471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307471", "type": "external" } ], "gene_names_uniprotkb": "Trhde", "gene_names_refseq": "Trhde", "protein_names_uniprotkb": "Thyrotropin-releasing hormone-degrading ectoenzyme; 3.4.19.6; Pyroglutamyl-peptidase II; TRH-specific aminopeptidase; Thyroliberinase", "protein_names_refseq": "thyrotropin-releasing hormone-degrading ectoenzyme isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762211)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Specific inactivation of TRH after its release., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016920 pyroglutamyl-peptidase activity;GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0043171 peptide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HC19-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HDU2-1", "uniprot_id": [ { "id": "A0A9J7HDU2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HDU2", "type": "external" } ], "mass": 30698.0, "length": 283, "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "LOC100750613", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like", "refseq_ac": [ { "id": "XP_035308420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308420", "type": "external" } ], "gene_names_uniprotkb": "LOC100750613", "gene_names_refseq": "LOC100750613", "protein_names_uniprotkb": "Non-selective voltage-gated ion channel VDAC1; Voltage-dependent anion-selective channel protein 1", "protein_names_refseq": "LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100750613)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0015288 porin activity;GO:0008308 voltage-gated monoatomic anion channel activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0046930 pore complex", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HDU2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HDX1-1", "uniprot_id": [ { "id": "A0A9J7HDX1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HDX1", "type": "external" } ], "mass": 51470.0, "length": 459, "protein_name": "Phosphotransferase", "gene_name": "Gck", "organism": "Hamster", "refseq_name": "hexokinase-4 isoform X2", "refseq_ac": [ { "id": "XP_035308915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308915", "type": "external" } ], "gene_names_uniprotkb": "Gck", "gene_names_refseq": "Gck", "protein_names_uniprotkb": "Phosphotransferase; 2.7.1.-", "protein_names_refseq": "hexokinase-4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763110)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" } ], "go_molecular_function": "GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0019158 mannokinase activity;GO:0005524 ATP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0032024 positive regulation of insulin secretion;GO:0006006 glucose metabolic process;GO:0001678 intracellular glucose homeostasis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HDX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HE01-1", "uniprot_id": [ { "id": "A0A9J7HE01_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HE01", "type": "external" } ], "mass": 15100.0, "length": 131, "protein_name": "Bis(5'-adenosyl)-triphosphatase", "gene_name": "Fhit", "organism": "Hamster", "refseq_name": "bis(5'-adenosyl)-triphosphatase", "refseq_ac": [ { "id": "XP_027293789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027293789", "type": "external" } ], "gene_names_uniprotkb": "Fhit", "gene_names_refseq": "Fhit", "protein_names_uniprotkb": "Bis(5'-adenosyl)-triphosphatase; 2.7.7.51; 3.6.1.29; 3.6.2.1; AP3A hydrolase; Adenosine 5'-monophosphoramidase FHIT; Adenylylsulfatase; Adenylylsulfate-ammonia adenylyltransferase; Diadenosine 5',5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein", "protein_names_refseq": "bis(5'-adenosyl)-triphosphatase", "tax_id": 10029, "disease": "", "pathway": " (cge:100755382)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 11% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614063.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.29", "type": "external" }, { "id": "3.1.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.1", "type": "external" }, { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "2.7.7.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.51", "type": "external" }, { "id": "3.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0031625 ubiquitin protein ligase binding;GO:0047710 bis(5'-adenosyl)-triphosphatase activity;GO:0047352 adenylylsulfate-ammonia adenylyltransferase activity;GO:0047627 adenylylsulfatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0015964 diadenosine triphosphate catabolic process;GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006163 purine nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HE01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HE43-1", "uniprot_id": [ { "id": "A0A9J7HE43_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HE43", "type": "external" } ], "mass": 129039.0, "length": 1156, "protein_name": "Receptor protein-tyrosine kinase", "gene_name": "Egfr", "organism": "Hamster", "refseq_name": "epidermal growth factor receptor isoform X2", "refseq_ac": [ { "id": "XP_035309195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309195", "type": "external" } ], "gene_names_uniprotkb": "Egfr", "gene_names_refseq": "Egfr", "protein_names_uniprotkb": "Receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "epidermal growth factor receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774580)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005006 epidermal growth factor receptor activity;GO:0048408 epidermal growth factor binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0031965 nuclear membrane;GO:0043235 receptor complex;GO:0005789 endoplasmic reticulum membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0043066 negative regulation of apoptotic process;GO:0009966 regulation of signal transduction;GO:0050679 positive regulation of epithelial cell proliferation;GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HE43-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7HVL1-1", "uniprot_id": [ { "id": "A0A9J7HVL1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7HVL1", "type": "external" } ], "mass": 34089.0, "length": 304, "protein_name": "Iodothyronine deiodinase", "gene_name": "Dio3", "organism": "Hamster", "refseq_name": "thyroxine 5-deiodinase", "refseq_ac": [ { "id": "NP_001243713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243713", "type": "external" } ], "gene_names_uniprotkb": "Dio3", "gene_names_refseq": "Dio3", "protein_names_uniprotkb": "Iodothyronine deiodinase", "protein_names_refseq": "deiodinase, iodothyronine type III; thyroxine 5-deiodinase; type III iodothyronine deiodinase", "tax_id": 10029, "disease": "", "pathway": " (cge:100753739)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AFTD01047644.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033798 thyroxine 5-deiodinase activity;GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0042446 hormone biosynthetic process;GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7HVL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J8E1-1", "uniprot_id": [ { "id": "A0A9J7J8E1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J8E1", "type": "external" } ], "mass": 205566.0, "length": 1963, "protein_name": "Neurogenic locus notch homolog protein 4", "gene_name": "Notch4", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4 isoform X2", "refseq_ac": [ { "id": "XP_027244558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244558", "type": "external" } ], "gene_names_uniprotkb": "Notch4", "gene_names_refseq": "Notch4", "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 4", "protein_names_refseq": "LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765940)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0006355 regulation of DNA-templated transcription;GO:0045595 regulation of cell differentiation;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J8E1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J9I3-1", "uniprot_id": [ { "id": "A0A9J7J9I3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J9I3", "type": "external" } ], "mass": 61811.0, "length": 557, "protein_name": "Solute carrier family 22 member 1", "gene_name": "Slc22a1", "organism": "Hamster", "refseq_name": "solute carrier family 22 member 1", "refseq_ac": [ { "id": "XP_027256897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256897", "type": "external" } ], "gene_names_uniprotkb": "Slc22a1", "gene_names_refseq": "Slc22a1", "protein_names_uniprotkb": "Solute carrier family 22 member 1", "protein_names_refseq": "solute carrier family 22 member 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763203)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0019534 toxin transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:1990748 cellular detoxification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J9I3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7J9W8-1", "uniprot_id": [ { "id": "A0A9J7J9W8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7J9W8", "type": "external" } ], "mass": 60089.0, "length": 527, "protein_name": "Beta-hexosaminidase", "gene_name": "LOC100756951", "organism": "Hamster", "refseq_name": "beta-hexosaminidase subunit beta", "refseq_ac": [ { "id": "XP_027257477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257477", "type": "external" } ], "gene_names_uniprotkb": "LOC100756951", "gene_names_refseq": "LOC100756951", "protein_names_uniprotkb": "Beta-hexosaminidase; 3.2.1.52", "protein_names_refseq": "beta-hexosaminidase subunit beta", "tax_id": 10029, "disease": "", "pathway": " (cge:100756951)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.52", "type": "external" } ], "go_molecular_function": "GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005764 lysosome;GO:0060473 cortical granule", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0005975 carbohydrate metabolic process;GO:0030203 glycosaminoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7J9W8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JAC5-1", "uniprot_id": [ { "id": "A0A9J7JAC5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JAC5", "type": "external" } ], "mass": 513878.0, "length": 4688, "protein_name": "E3 ubiquitin-protein ligase MYCBP2", "gene_name": "Mycbp2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MYCBP2 isoform X2", "refseq_ac": [ { "id": "XP_027249785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249785", "type": "external" } ], "gene_names_uniprotkb": "Mycbp2", "gene_names_refseq": "Mycbp2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MYCBP2; 2.3.2.33; Myc-binding protein 2; Protein associated with Myc", "protein_names_refseq": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MYCBP2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763589)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027249785.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0030424 axon", "go_biological_process": "GO:0032922 circadian regulation of gene expression;GO:0007411 axon guidance;GO:0008582 regulation of synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JAC5-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JBJ1-1", "uniprot_id": [ { "id": "A0A9J7JBJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JBJ1", "type": "external" } ], "mass": 107862.0, "length": 943, "protein_name": "Aminopeptidase", "gene_name": "Enpep", "organism": "Hamster", "refseq_name": "glutamyl aminopeptidase isoform X3", "refseq_ac": [ { "id": "XP_027251491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251491", "type": "external" } ], "gene_names_uniprotkb": "Enpep", "gene_names_refseq": "Enpep", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "glutamyl aminopeptidase isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100757489)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity;GO:0004230 glutamyl aminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005903 brush border;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0016485 protein processing;GO:0008217 regulation of blood pressure;GO:0043171 peptide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JBJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JF26-1", "uniprot_id": [ { "id": "A0A9J7JF26_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JF26", "type": "external" } ], "mass": 90530.0, "length": 811, "protein_name": "Plasminogen", "gene_name": "Plg", "organism": "Hamster", "refseq_name": "plasminogen", "refseq_ac": [ { "id": "XP_027256900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256900", "type": "external" } ], "gene_names_uniprotkb": "Plg", "gene_names_refseq": "Plg", "protein_names_uniprotkb": "Plasminogen; 3.4.21.7", "protein_names_refseq": "plasminogen", "tax_id": 10029, "disease": "", "pathway": " (cge:100761455)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027256900.1. COMPLETENESS: full length., [RefSeq]; Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo., [UniProtKB, UniProtKB]; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1, C4 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0042730 fibrinolysis;GO:0048771 tissue remodeling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JF26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JGC9-1", "uniprot_id": [ { "id": "A0A9J7JGC9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JGC9", "type": "external" } ], "mass": 47878.0, "length": 419, "protein_name": "Fatty acid 2-hydroxylase", "gene_name": "Fa2h", "organism": "Hamster", "refseq_name": "fatty acid 2-hydroxylase isoform X2", "refseq_ac": [ { "id": "XP_027261835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261835", "type": "external" } ], "gene_names_uniprotkb": "Fa2h", "gene_names_refseq": "Fa2h", "protein_names_uniprotkb": "Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase", "protein_names_refseq": "fatty acid 2-hydroxylase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771615)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027261835.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0080132 fatty acid 2-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0006682 galactosylceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JGC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JGY9-1", "uniprot_id": [ { "id": "A0A9J7JGY9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JGY9", "type": "external" } ], "mass": 89902.0, "length": 835, "protein_name": "PAN2-PAN3 deadenylation complex subunit PAN3", "gene_name": "Pan3", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: PAN2-PAN3 deadenylation complex subunit PAN3 isoform X4", "refseq_ac": [ { "id": "XP_027269494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269494", "type": "external" } ], "gene_names_uniprotkb": "Pan3; PAN3", "gene_names_refseq": "Pan3", "protein_names_uniprotkb": "PAN2-PAN3 deadenylation complex subunit PAN3; PAB1P-dependent poly(A)-specific ribonuclease; PAN deadenylation complex subunit 3; Poly(A)-nuclease deadenylation complex subunit 3", "protein_names_refseq": "LOW QUALITY PROTEIN: PAN2-PAN3 deadenylation complex subunit PAN3 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100757082)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027269494.1. COMPLETENESS: full length., [RefSeq]; Decreases PAN2-mediated deadenylation, possibly by preventing progression into the second CCR4-NOT mediated stage of biphasic deadenylation. Has a significant effect on mRNA stability, generally stabilizing a subset of the transcriptome. Stabilizes mRNAs degraded by the AU-rich element (ARE)-mediated mRNA decay pathway but promotes degradation of mRNAs by the microRNA-mediated pathway. Its activity influences mRNP remodeling, specifically reducing formation of a subset of P-bodies containing GW220, an isoform of TNRC6A., [UniProtKB, UniProtKB]; Enhances PAN2 deadenylase activity and has an extensive effect on mRNA stability, generally enhancing mRNA decay across the transcriptome by multiple pathways, including the AU-rich element (ARE)-mediated pathway, microRNA-mediated pathway and the nonsense-mediated pathway (NMD). Its activity is required for efficient P-body formation. May be involved in regulating mRNAs of genes involved in cell cycle progression and cell proliferation., [UniProtKB, UniProtKB]; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0008143 poly(A) binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0031251 PAN complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JGY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JHU6-1", "uniprot_id": [ { "id": "A0A9J7JHU6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JHU6", "type": "external" } ], "mass": 174510.0, "length": 1556, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp10a", "organism": "Hamster", "refseq_name": "probable phospholipid-transporting ATPase VA isoform X2", "refseq_ac": [ { "id": "XP_027260531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260531", "type": "external" } ], "gene_names_uniprotkb": "Atp10a", "gene_names_refseq": "Atp10a", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "probable phospholipid-transporting ATPase VA isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774607)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane. Initiates inward plasma membrane bending and recruitment of Bin/amphiphysin/Rvs (BAR) domain-containing proteins involved in membrane tubulation and cell trafficking. Facilitates ITGB1/beta1 integrin endocytosis, delaying cell adhesion and cell spreading on extracellular matrix. Has low flippase activity toward glucosylceramide (GlcCer)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140351 glycosylceramide flippase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:1990531 phospholipid-translocating ATPase complex", "go_biological_process": "GO:0045332 phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JHU6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JI07-1", "uniprot_id": [ { "id": "A0A9J7JI07_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JI07", "type": "external" } ], "mass": 39718.0, "length": 356, "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5", "gene_name": "Abhd5", "organism": "Hamster", "refseq_name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X2", "refseq_ac": [ { "id": "XP_027271274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271274", "type": "external" } ], "gene_names_uniprotkb": "Abhd5", "gene_names_refseq": "Abhd5", "protein_names_uniprotkb": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 2.3.1.51; Abhydrolase domain-containing protein 5; Lipid droplet-binding protein CGI-58", "protein_names_refseq": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769851)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors. Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0052689 carboxylic ester hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005811 lipid droplet", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0010891 negative regulation of triglyceride storage;GO:0010898 positive regulation of triglyceride catabolic process;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JI07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JIA7-1", "uniprot_id": [ { "id": "A0A9J7JIA7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JIA7", "type": "external" } ], "mass": 17998.0, "length": 163, "protein_name": "Phospholipase A2", "gene_name": "LOC100763432", "organism": "Hamster", "refseq_name": "phospholipase A2 isoform X2", "refseq_ac": [ { "id": "XP_027271872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271872", "type": "external" } ], "gene_names_uniprotkb": "LOC100763432", "gene_names_refseq": "LOC100763432", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763432)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 20% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JIA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JIA9-1", "uniprot_id": [ { "id": "A0A9J7JIA9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JIA9", "type": "external" } ], "mass": 98570.0, "length": 884, "protein_name": "Cadherin-1", "gene_name": "Cdh1", "organism": "Hamster", "refseq_name": "cadherin-1", "refseq_ac": [ { "id": "XP_027261727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261727", "type": "external" } ], "gene_names_uniprotkb": "Cdh1", "gene_names_refseq": "Cdh1", "protein_names_uniprotkb": "Cadherin-1; Epithelial cadherin; Uvomorulin", "protein_names_refseq": "cadherin-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758185)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Promotes organization of radial actin fiber structure and cellular response to contractile forces, via its interaction with AMOTL2 which facilitates anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane. Plays a role in the early stages of desmosome cell-cell junction formation via facilitating the recruitment of DSG2 and DSP to desmosome plaques. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7., [UniProtKB, UniProtKB]; E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005912 adherens junction;GO:0016342 catenin complex;GO:0030057 desmosome", "go_biological_process": "GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0007416 synapse assembly;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JIA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JIG6-1", "uniprot_id": [ { "id": "A0A9J7JIG6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JIG6", "type": "external" } ], "mass": 71890.0, "length": 658, "protein_name": "Terminal nucleotidyltransferase 4B", "gene_name": "Tent4b", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: terminal nucleotidyltransferase 4B isoform X3", "refseq_ac": [ { "id": "XP_027261325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261325", "type": "external" } ], "gene_names_uniprotkb": "Tent4b", "gene_names_refseq": "Tent4b", "protein_names_uniprotkb": "Terminal nucleotidyltransferase 4B; 2.7.7.19; Non-canonical poly(A) RNA polymerase PAPD5; PAP-associated domain-containing protein 5; Terminal guanylyltransferase; Terminal uridylyltransferase 3; Topoisomerase-related function protein 4-2", "protein_names_refseq": "LOW QUALITY PROTEIN: terminal nucleotidyltransferase 4B isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100759123)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity;GO:0070568 guanylyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0031499 TRAMP complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0051301 cell division;GO:0006364 rRNA processing;GO:0031123 RNA 3'-end processing;GO:1905870 positive regulation of 3'-UTR-mediated mRNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JIG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JJR3-1", "uniprot_id": [ { "id": "A0A9J7JJR3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JJR3", "type": "external" } ], "mass": 98129.0, "length": 862, "protein_name": "Polycystin-2-like protein 1", "gene_name": "Pkd2l1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: polycystic kidney disease 2-like 1 protein", "refseq_ac": [ { "id": "XP_027263040", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263040", "type": "external" } ], "gene_names_uniprotkb": "Pkd2l1", "gene_names_refseq": "Pkd2l1", "protein_names_uniprotkb": "Polycystin-2-like protein 1; Polycystic kidney disease 2-like 1 protein; Polycystin-2 homolog", "protein_names_refseq": "LOW QUALITY PROTEIN: polycystic kidney disease 2-like 1 protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100753844)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027263040.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0051371 muscle alpha-actinin binding;GO:0005262 calcium channel activity;GO:0005509 calcium ion binding;GO:0005272 sodium channel activity;GO:0015269 calcium-activated potassium channel activity", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0034704 calcium channel complex;GO:0060170 ciliary membrane", "go_biological_process": "GO:0051262 protein tetramerization;GO:0050915 sensory perception of sour taste;GO:0050982 detection of mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JJR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JK53-1", "uniprot_id": [ { "id": "A0A9J7JK53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JK53", "type": "external" } ], "mass": 48589.0, "length": 414, "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "gene_name": "Sgms1", "organism": "Hamster", "refseq_name": "phosphatidylcholine:ceramide cholinephosphotransferase 1", "refseq_ac": [ { "id": "XP_027262201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262201", "type": "external" } ], "gene_names_uniprotkb": "Sgms1", "gene_names_refseq": "Sgms1", "protein_names_uniprotkb": "Phosphatidylcholine:ceramide cholinephosphotransferase 1; 2.7.8.27; Protein Mob; Sphingomyelin synthase 1; Transmembrane protein 23", "protein_names_refseq": "phosphatidylcholine:ceramide cholinephosphotransferase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766719)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.62", "type": "external" }, { "id": "2.7.8.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.27", "type": "external" } ], "go_molecular_function": "GO:0033188 sphingomyelin synthase activity;GO:0047493 ceramide cholinephosphotransferase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006686 sphingomyelin biosynthetic process;GO:0046513 ceramide biosynthetic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JK53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JN73-1", "uniprot_id": [ { "id": "A0A9J7JN73_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JN73", "type": "external" } ], "mass": 17276.0, "length": 152, "protein_name": "Phospholipase A2", "gene_name": "LOC100765466", "organism": "Hamster", "refseq_name": "phospholipase A2-like", "refseq_ac": [ { "id": "XP_007649565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649565", "type": "external" } ], "gene_names_uniprotkb": "LOC100765466", "gene_names_refseq": "LOC100765466", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100765466)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614968.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JN73-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JNC0-1", "uniprot_id": [ { "id": "A0A9J7JNC0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JNC0", "type": "external" } ], "mass": 200827.0, "length": 1732, "protein_name": "Unconventional myosin-Va", "gene_name": "Myo5c", "organism": "Hamster", "refseq_name": "unconventional myosin-Vc isoform X2", "refseq_ac": [ { "id": "XP_027266947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266947", "type": "external" } ], "gene_names_uniprotkb": "Myo5c", "gene_names_refseq": "Myo5c", "protein_names_uniprotkb": "Unconventional myosin-Va; Dilute myosin heavy chain, non-muscle; Unconventional myosin-Vb", "protein_names_refseq": "unconventional myosin-Vc isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753160)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. Required for proper localization of bile salt export pump ABCB11 at the apical/canalicular plasma membrane of hepatocytes., [UniProtKB, UniProtKB]; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0016020 membrane;GO:0030141 secretory granule;GO:0016459 myosin complex;GO:0042641 actomyosin;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0007015 actin filament organization;GO:0015031 protein transport;GO:0030050 vesicle transport along actin filament;GO:0043473 pigmentation;GO:0018958 phenol-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JNC0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JNW1-1", "uniprot_id": [ { "id": "A0A9J7JNW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JNW1", "type": "external" } ], "mass": 74755.0, "length": 661, "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "Acox1", "organism": "Hamster", "refseq_name": "peroxisomal acyl-coenzyme A oxidase 1 isoform X3", "refseq_ac": [ { "id": "XP_027281411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281411", "type": "external" } ], "gene_names_uniprotkb": "Acox1", "gene_names_refseq": "Acox1", "protein_names_uniprotkb": "Acyl-coenzyme A oxidase", "protein_names_refseq": "peroxisomal acyl-coenzyme A oxidase 1 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100689199)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2))., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" } ], "go_molecular_function": "GO:0005504 fatty acid binding;GO:0071949 FAD binding;GO:0003997 acyl-CoA oxidase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0000038 very long-chain fatty acid metabolic process;GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase;GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JNW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JQ06-1", "uniprot_id": [ { "id": "A0A9J7JQ06_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JQ06", "type": "external" } ], "mass": 39427.0, "length": 362, "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "Vdac1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027283358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283358", "type": "external" } ], "gene_names_uniprotkb": "Vdac1", "gene_names_refseq": "Vdac1", "protein_names_uniprotkb": "Non-selective voltage-gated ion channel VDAC1; Voltage-dependent anion-selective channel protein 1", "protein_names_refseq": "LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765792)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0015288 porin activity;GO:0008308 voltage-gated monoatomic anion channel activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0046930 pore complex", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JQ06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JQ85-1", "uniprot_id": [ { "id": "A0A9J7JQ85_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JQ85", "type": "external" } ], "mass": 82536.0, "length": 744, "protein_name": "Vesicle-fusing ATPase", "gene_name": "Nsf", "organism": "Hamster", "refseq_name": "vesicle-fusing ATPase isoform X1", "refseq_ac": [ { "id": "XP_007606206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606206", "type": "external" } ], "gene_names_uniprotkb": "Nsf", "gene_names_refseq": "Nsf", "protein_names_uniprotkb": "Vesicle-fusing ATPase; 3.6.4.6", "protein_names_refseq": "vesicle-fusing ATPase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770898)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 2223 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003622620.1) and transcript sequence (IACG01091083.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005795 Golgi stack", "go_biological_process": "GO:0035494 SNARE complex disassembly;GO:0006886 intracellular protein transport;GO:0001921 positive regulation of receptor recycling;GO:0043001 Golgi to plasma membrane protein transport;GO:0045732 positive regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JQ85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JRI3-1", "uniprot_id": [ { "id": "A0A9J7JRI3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JRI3", "type": "external" } ], "mass": 197224.0, "length": 1739, "protein_name": "Serine/threonine-protein kinase MRCK beta", "gene_name": "Cdc42bpb", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase MRCK beta isoform X3", "refseq_ac": [ { "id": "XP_027272434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272434", "type": "external" } ], "gene_names_uniprotkb": "Cdc42bpb", "gene_names_refseq": "Cdc42bpb", "protein_names_uniprotkb": "Serine/threonine-protein kinase MRCK beta; 2.7.11.1; CDC42-binding protein kinase beta; DMPK-like beta; Myotonic dystrophy kinase-related CDC42-binding kinase beta", "protein_names_refseq": "serine/threonine-protein kinase MRCK beta isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773684)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A. In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0042641 actomyosin;GO:0070161 anchoring junction", "go_biological_process": "GO:0016477 cell migration;GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JRI3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JR59-1", "uniprot_id": [ { "id": "A0A9J7JR59_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JR59", "type": "external" } ], "mass": 15702.0, "length": 140, "protein_name": "Phospholipase A2", "gene_name": "LOC100752205", "organism": "Hamster", "refseq_name": "phospholipase A2", "refseq_ac": [ { "id": "XP_027271873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271873", "type": "external" } ], "gene_names_uniprotkb": "LOC100752205", "gene_names_refseq": "LOC100752205", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "phospholipase A2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752205)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0048146 positive regulation of fibroblast proliferation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JR59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JUA9-1", "uniprot_id": [ { "id": "A0A9J7JUA9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JUA9", "type": "external" } ], "mass": 142546.0, "length": 1315, "protein_name": "Glutamate receptor", "gene_name": "Grin2d", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D isoform X2", "refseq_ac": [ { "id": "XP_027276377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276377", "type": "external" } ], "gene_names_uniprotkb": "Grin2d", "gene_names_refseq": "Grin2d", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750615)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 6 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+). Participates in synaptic plasticity for learning and memory formation. Channel activation requires binding of the neurotransmitter L-glutamate to the GluN2 subunit, glycine or D-serine binding to the GluN1 subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). NMDARs mediate simultaneously the potassium efflux and the influx of calcium and sodium. Each GluN2 subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, Ca2(+) permeability, and binding to allosteric modulators., [UniProtKB, UniProtKB]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004972 NMDA glutamate receptor activity", "go_cellular_component": "GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0031644 regulation of nervous system process;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JUA9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JUV7-1", "uniprot_id": [ { "id": "A0A9J7JUV7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JUV7", "type": "external" } ], "mass": 71533.0, "length": 621, "protein_name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "gene_name": "Samhd1", "organism": "Hamster", "refseq_name": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "refseq_ac": [ { "id": "XP_007605967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007605967", "type": "external" } ], "gene_names_uniprotkb": "Samhd1", "gene_names_refseq": "Samhd1", "protein_names_uniprotkb": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; SAM domain and HD domain-containing protein 1", "protein_names_refseq": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763736)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613641.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007605967.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0008832 dGTPase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0045087 innate immune response;GO:0051289 protein homotetramerization;GO:0051607 defense response to virus;GO:0006203 dGTP catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JUV7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JUW1-1", "uniprot_id": [ { "id": "A0A9J7JUW1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JUW1", "type": "external" } ], "mass": 119173.0, "length": 1040, "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "Rag1", "organism": "Hamster", "refseq_name": "V(D)J recombination-activating protein 1", "refseq_ac": [ { "id": "XP_027276834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276834", "type": "external" } ], "gene_names_uniprotkb": "Rag1", "gene_names_refseq": "Rag1", "protein_names_uniprotkb": "V(D)J recombination-activating protein 1; 2.3.2.27; 3.1.-.-", "protein_names_refseq": "V(D)J recombination-activating protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754292)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0097519 DNA recombinase complex;GO:1905347 endodeoxyribonuclease complex", "go_biological_process": "GO:0002250 adaptive immune response;GO:0006325 chromatin organization;GO:0033077 T cell differentiation in thymus;GO:0002331 pre-B cell allelic exclusion;GO:0033151 V(D)J recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JUW1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JUY8-1", "uniprot_id": [ { "id": "A0A9J7JUY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JUY8", "type": "external" } ], "mass": 99274.0, "length": 866, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Itch", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase Itchy homolog", "refseq_ac": [ { "id": "XP_003501174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501174", "type": "external" } ], "gene_names_uniprotkb": "Itch", "gene_names_refseq": "Itch", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase Itchy homolog", "tax_id": 10029, "disease": "", "pathway": " (cge:100751263)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613833.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:1902532 negative regulation of intracellular signal transduction;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0006915 apoptotic process;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JUY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYK6-1", "uniprot_id": [ { "id": "A0A9J7JYK6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYK6", "type": "external" } ], "mass": 34841.0, "length": 317, "protein_name": "Hepatic sodium/bile acid cotransporter", "gene_name": "Slc10a1", "organism": "Hamster", "refseq_name": "sodium/bile acid cotransporter", "refseq_ac": [ { "id": "XP_035301066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301066", "type": "external" } ], "gene_names_uniprotkb": "Slc10a1", "gene_names_refseq": "Slc10a1", "protein_names_uniprotkb": "Hepatic sodium/bile acid cotransporter; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1", "protein_names_refseq": "sodium/bile acid cotransporter", "tax_id": 10029, "disease": "", "pathway": " (cge:100756998)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008508 bile acid:sodium symporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZM7-1", "uniprot_id": [ { "id": "A0A9J7JZM7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZM7", "type": "external" } ], "mass": 124456.0, "length": 1135, "protein_name": "Protein deacetylase HDAC6", "gene_name": "Hdac6", "organism": "Hamster", "refseq_name": "histone deacetylase 6", "refseq_ac": [ { "id": "XP_027289117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289117", "type": "external" } ], "gene_names_uniprotkb": "Hdac6", "gene_names_refseq": "Hdac6", "protein_names_uniprotkb": "Protein deacetylase HDAC6; Tubulin-lysine deacetylase HDAC6", "protein_names_refseq": "histone deacetylase 6", "tax_id": 10029, "disease": "", "pathway": " (cge:100763688)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0016740 transferase activity;GO:0004407 histone deacetylase activity", "go_cellular_component": "GO:0005813 centrosome;GO:0030424 axon;GO:0030425 dendrite;GO:0043204 perikaryon;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006914 autophagy;GO:0006950 response to stress;GO:0040029 epigenetic regulation of gene expression;GO:0051646 mitochondrion localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZM7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZN1-1", "uniprot_id": [ { "id": "A0A9J7JZN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZN1", "type": "external" } ], "mass": 84529.0, "length": 763, "protein_name": "Amine oxidase", "gene_name": "Aoc3", "organism": "Hamster", "refseq_name": "membrane primary amine oxidase", "refseq_ac": [ { "id": "XP_027283859", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283859", "type": "external" } ], "gene_names_uniprotkb": "Aoc3", "gene_names_refseq": "Aoc3", "protein_names_uniprotkb": "Amine oxidase; 1.4.3.-", "protein_names_refseq": "membrane primary amine oxidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100762926)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005507 copper ion binding;GO:0008131 primary methylamine oxidase activity;GO:0048038 quinone binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0046677 response to antibiotic;GO:0009308 amine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0D5-1", "uniprot_id": [ { "id": "A0A9J7K0D5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0D5", "type": "external" } ], "mass": 97198.0, "length": 877, "protein_name": "Cytosolic carboxypeptidase-like protein 5", "gene_name": "Agbl5", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: cytosolic carboxypeptidase-like protein 5", "refseq_ac": [ { "id": "XP_035294484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294484", "type": "external" } ], "gene_names_uniprotkb": "Agbl5", "gene_names_refseq": "Agbl5", "protein_names_uniprotkb": "Cytosolic carboxypeptidase-like protein 5; 3.4.17.24; ATP/GTP-binding protein-like 5; Protein deglutamylase CCP5", "protein_names_refseq": "LOW QUALITY PROTEIN: cytosolic carboxypeptidase-like protein 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100762486)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate. Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin. Mediates deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.17.24", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.24", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005829 cytosol;GO:0030496 midbody", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0D5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0P8-1", "uniprot_id": [ { "id": "A0A9J7K0P8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0P8", "type": "external" } ], "mass": 20512.0, "length": 180, "protein_name": "Cytoglobin", "gene_name": "Cygb", "organism": "Hamster", "refseq_name": "cytoglobin isoform X2", "refseq_ac": [ { "id": "XP_035303874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303874", "type": "external" } ], "gene_names_uniprotkb": "Cygb", "gene_names_refseq": "Cygb", "protein_names_uniprotkb": "Cytoglobin; 1.15.1.1; Nitrite reductase CYGB; Pseudoperoxidase CYGB; Superoxide dismutase CYGB", "protein_names_refseq": "cytoglobin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762644)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable multifunctional globin with a hexacoordinated heme iron required for the catalysis of various reactions depending on redox condition of the cell as well as oxygen availability. Has a nitric oxide dioxygenase (NOD) activity and is most probably involved in cell-mediated and oxygen-dependent nitric oxide consumption. By scavenging this second messenger may regulate several biological processes including endothelium-mediated vasodilation and vascular tone. Under normoxic conditions functions as a nitric oxide dioxygenase (NOD) but under hypoxic conditions the globin may switch its function to that of a nitrite (NO2) reductase (NiR), generating nitric oxide. Could also have peroxidase and superoxide dismutase activities, detoxifying reactive oxygen species and protecting cells against oxidative stress. Also binds dioxygen with low affinity and could function as an oxygen sensor but has probably no function as a respiratory oxygen carrier., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004784 superoxide dismutase activity;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046210 nitric oxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0P8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0U7-1", "uniprot_id": [ { "id": "A0A9J7K0U7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0U7", "type": "external" } ], "mass": 173507.0, "length": 1584, "protein_name": "Adhesion G protein-coupled receptor B1", "gene_name": "Adgrb1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: adhesion G protein-coupled receptor B1 isoform X2", "refseq_ac": [ { "id": "XP_035295060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295060", "type": "external" } ], "gene_names_uniprotkb": "Adgrb1", "gene_names_refseq": "Adgrb1", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor B1; Brain-specific angiogenesis inhibitor 1", "protein_names_refseq": "LOW QUALITY PROTEIN: adhesion G protein-coupled receptor B1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766156)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibits angiogenesis in a CD36-dependent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005576 extracellular region;GO:0005925 focal adhesion;GO:0014069 postsynaptic density;GO:0043197 dendritic spine", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007399 nervous system development;GO:0045087 innate immune response;GO:0007517 muscle organ development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0U7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2B3-1", "uniprot_id": [ { "id": "A0A9J7K2B3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2B3", "type": "external" } ], "mass": 35548.0, "length": 331, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC113837666", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase-like isoform X2", "refseq_ac": [ { "id": "XP_035306057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306057", "type": "external" } ], "gene_names_uniprotkb": "LOC113837666", "gene_names_refseq": "LOC113837666", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113837666)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2B3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K381-1", "uniprot_id": [ { "id": "A0A9J7K381_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K381", "type": "external" } ], "mass": 182708.0, "length": 1606, "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "Cftr", "organism": "Hamster", "refseq_name": "cystic fibrosis transmembrane conductance regulator", "refseq_ac": [ { "id": "XP_035307288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307288", "type": "external" } ], "gene_names_uniprotkb": "Cftr", "gene_names_refseq": "Cftr", "protein_names_uniprotkb": "Cystic fibrosis transmembrane conductance regulator; 5.6.1.6; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel", "protein_names_refseq": "cystic fibrosis transmembrane conductance regulator", "tax_id": 10029, "disease": "", "pathway": " (cge:100754506)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 9% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Possesses an intrinsic ATPase activity and utilizes ATP to gate its channel; the passive flow of anions through the channel is gated by cycles of ATP binding and hydrolysis by the ATP-binding domains. The ion channel is also permeable to HCO(3)(-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005260 intracellularly ATP-gated chloride channel activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0015701 bicarbonate transport;GO:0097186 amelogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K381-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K383-1", "uniprot_id": [ { "id": "A0A9J7K383_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K383", "type": "external" } ], "mass": 276160.0, "length": 2465, "protein_name": "Teneurin-1", "gene_name": "Tenm1", "organism": "Hamster", "refseq_name": "teneurin-1 isoform X2", "refseq_ac": [ { "id": "XP_027289325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289325", "type": "external" } ], "gene_names_uniprotkb": "Tenm1", "gene_names_refseq": "Tenm1", "protein_names_uniprotkb": "Teneurin-1; Protein Odd Oz/ten-m homolog 1; Tenascin-M1; Teneurin transmembrane protein 1", "protein_names_refseq": "teneurin-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757724)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Induces gene transcription activation., [UniProtKB, UniProtKB]; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer., [UniProtKB, UniProtKB]; Plays a role in the regulation of neuroplasticity in the limbic system. Mediates a rapid reorganization of actin- and tubulin-based cytoskeleton elements with an increase in dendritic arborization and spine density formation of neurons in the hippocampus and amygdala. Induces BDNF transcription inhibition in neurons. Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and extracellular signal-regulated kinase (ERK) cascade. Also acts as a bioactive neuroprotective peptide on limbic neurons of the brain and regulates stress-induced behavior: attenuates alkalosis-associated necrotic cell death and the effects of corticotropin-releasing factor (CRF) on c-fos/FOS induction and on the reinstatement of cocaine seeking., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0016607 nuclear speck;GO:0043005 neuron projection;GO:0016363 nuclear matrix", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007218 neuropeptide signaling pathway;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K383-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q80WN7-1", "uniprot_id": [ { "id": "B4GT4_CRIGR", "url": "https://www.uniprot.org/uniprot/Q80WN7", "type": "external" } ], "mass": 39893.0, "length": 344, "protein_name": "Beta-1,4-galactosyltransferase 4", "gene_name": "B4GALT4", "organism": "Hamster", "refseq_name": "beta-1,4-galactosyltransferase 4", "refseq_ac": [ { "id": "NP_001233624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233624", "type": "external" } ], "gene_names_uniprotkb": "B4GALT4", "gene_names_refseq": "B4galt4; b4Gal-T4", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase 4; 2.4.1.-; 2.4.1.275; 2.4.1.90; Beta-1,4-GalTase 4; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta4Gal-T4; Lactotriaosylceramide beta-1,4-galactosyltransferase; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4; b4Gal-T4", "protein_names_refseq": "Beta-1,4-GalTase 4; Beta4Gal-T4; N-acetyllactosamine synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4; beta-1,4-galactosyltransferase 4; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; lactotriaosylceramide beta-1,4-galactosyltransferase; nal synthase", "tax_id": 10029, "disease": "", "pathway": " (cge:100689435)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14567696", "class_list": "glycogene;glycosyltransferase", "function": "Galactose (Gal) transferase involved in the synthesis of terminal N-acetyllactosamine (LacNac) unit present on glycan chains of glycoproteins and glycosphingolipids. Catalyzes the transfer of Gal residue via a beta1->4 linkage from UDP-Gal to the non-reducing terminal N-acetyl glucosamine 6-O-sulfate (6-O-sulfoGlcNAc) in the linearly growing chain of both N- and O-linked keratan sulfate proteoglycans. Cooperates with B3GNT7 N-acetyl glucosamine transferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono-and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer. Transfers Gal residue via a beta1->4 linkage to terminal 6-O-sulfoGlcNAc within the LacNac unit of core 2 O-glycans forming 6-sulfo-sialyl-Lewis X (sLex). May contribute to the generation of sLex epitope on mucin-type glycoproteins that serve as ligands for SELL/L-selectin, a major regulator of leukocyte migration. In the biosynthesis pathway of neolacto-series glycosphingolipids, transfers Gal residue via a beta1->4 linkage to terminal GlcNAc of a lactotriaosylceramide (Lc3Cer) acceptor to form a neolactotetraosylceramide. Efficiently galactosylates both non-sulfated and 6-O-sulfated terminal GlcNAc moities on G0 complex-type N-glycans., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.275", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.275", "type": "external" }, { "id": "2.4.1.90", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.90", "type": "external" }, { "id": "2.4.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.38", "type": "external" }, { "id": "2.4.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.22", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945 N-acetyllactosamine synthase activity;GO:0035250 UDP-galactosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0018146 keratan sulfate proteoglycan biosynthetic process;GO:0001572 lactosylceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q80WN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q80WN9-1", "uniprot_id": [ { "id": "B4GT2_CRIGR", "url": "https://www.uniprot.org/uniprot/Q80WN9", "type": "external" } ], "mass": 42005.0, "length": 369, "protein_name": "Beta-1,4-galactosyltransferase 2", "gene_name": "B4GALT2", "organism": "Hamster", "refseq_name": "beta-1,4-galactosyltransferase 2", "refseq_ac": [ { "id": "NP_001233623", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233623", "type": "external" } ], "gene_names_uniprotkb": "B4GALT2", "gene_names_refseq": "B4galt2; b4Gal-T2", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase 2; 2.4.1.-; 2.4.1.22; 2.4.1.38; 2.4.1.90; Beta-1,4-GalTase 2; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; Beta4Gal-T2; Lactose synthase A protein; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2; b4Gal-T2", "protein_names_refseq": "Beta-1,4-GalTase 2; Beta4Gal-T2; N-acetyllactosamine synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2; beta-1,4-galactosyltransferase 2; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; lactose synthase A protein; nal synthase", "tax_id": 10029, "disease": "", "pathway": " (cge:100689434)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14567696", "class_list": "glycogene;glycosyltransferase", "function": "##Evidence-Data-START## Transcript exon combination :: AY117536.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN09948071, SAMN09948081 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY117536.1., [RefSeq]; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.275", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.275", "type": "external" }, { "id": "2.4.1.90", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.90", "type": "external" }, { "id": "2.4.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.38", "type": "external" }, { "id": "2.4.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.22", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945 N-acetyllactosamine synthase activity;GO:0004461 lactose synthase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q80WN9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8K3U7-1", "uniprot_id": [ { "id": "PRDX2_CRIGR", "url": "https://www.uniprot.org/uniprot/Q8K3U7", "type": "external" } ], "mass": 21813.0, "length": 198, "protein_name": "Peroxiredoxin-2", "gene_name": "PRDX2", "organism": "Hamster", "refseq_name": "peroxiredoxin-2", "refseq_ac": [ { "id": "NP_001233709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233709", "type": "external" } ], "gene_names_uniprotkb": "PRDX2", "gene_names_refseq": "Prdx2", "protein_names_uniprotkb": "Peroxiredoxin-2; 1.11.1.24; Thioredoxin-dependent peroxiredoxin 2", "protein_names_refseq": "peroxiredoxin-2; thioredoxin-dependent peroxiredoxin 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689349)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF532110.1, JI877296.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06481668 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF532110.1., [RefSeq]; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" } ], "go_molecular_function": "GO:0008379 thioredoxin peroxidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045454 cell redox homeostasis;GO:0019430 removal of superoxide radicals;GO:0030194 positive regulation of blood coagulation;GO:0042744 hydrogen peroxide catabolic process;GO:0045321 leukocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8K3U7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8R2J9-1", "uniprot_id": [ { "id": "RA51C_CRIGR", "url": "https://www.uniprot.org/uniprot/Q8R2J9", "type": "external" } ], "mass": 40381.0, "length": 366, "protein_name": "DNA repair protein RAD51 homolog 3", "gene_name": "RAD51C", "organism": "Hamster", "refseq_name": "DNA repair protein RAD51 homolog 3", "refseq_ac": [ { "id": "NP_001231005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231005", "type": "external" } ], "gene_names_uniprotkb": "RAD51C; RAD51L2", "gene_names_refseq": "R51H3; Rad51c; rad51L2", "protein_names_uniprotkb": "DNA repair protein RAD51 homolog 3; R51H3; RAD51 homolog C; RAD51-like protein 2", "protein_names_refseq": "DNA repair protein RAD51 homolog 3; Protein phosphatase 1E; RAD51-like protein 2; putative DNA repair protein RAD51", "tax_id": 10029, "disease": "", "pathway": " (cge:100689078)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11912211;12000837;17268176;20471405", "class_list": "", "function": "Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Part of the RAD51 paralog protein complexes BCDX2 and CX3 which act at different stages of the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 seems to act downstream of BRCA2 recruitment and upstream of RAD51 recruitment; CX3 seems to act downstream of RAD51 recruitment; both complexes bind predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway. Involved in RAD51 foci formation in response to DNA damage suggesting an involvement in early stages of HR probably in the invasion step. Has an early function in DNA repair in facilitating phosphorylation of the checkpoint kinase CHEK2 and thereby transduction of the damage signal, leading to cell cycle arrest and HR activation. Participates in branch migration and HJ resolution and thus is important for processing HR intermediates late in the DNA repair process; the function may be linked to the CX3 complex. Part of a PALB2-scaffolded HR complex containing BRCA2 and which is thought to play a role in DNA repair by HR. Protects RAD51 from ubiquitin-mediated degradation that is enhanced following DNA damage. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and XRCC3. Contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Involved in maintaining centrosome number in mitosis., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8VDE9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000400 four-way junction DNA binding;GO:0008821 crossover junction DNA endonuclease activity;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0033065 Rad51C-XRCC3 complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0000707 meiotic DNA recombinase assembly;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8R2J9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9JIG1-1", "uniprot_id": [ { "id": "FUT9_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9JIG1", "type": "external" } ], "mass": 42071.0, "length": 359, "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "gene_name": "FUT9", "organism": "Hamster", "refseq_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "refseq_ac": [ { "id": "NP_001230953", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230953", "type": "external" } ], "gene_names_uniprotkb": "FUT9", "gene_names_refseq": "Fuc-TIX; FucT-IX; Fut9", "protein_names_uniprotkb": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9; 2.4.1.152; Fuc-TIX; FucT-IX; Fucosyltransferase 9; Fucosyltransferase IX; Galactoside 3-L-fucosyltransferase", "protein_names_refseq": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9; Fucosyltransferase IX; Galactoside 3-L-fucosyltransferase; alpha (1,3) fucosyltransferase type IX; alpha-(1,3)-fucosyltransferase 9; fucosyltransferase 9 (alpha (1,3) fucosyltransferase)", "tax_id": 10029, "disease": "", "pathway": " (cge:100689036)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10700388", "class_list": "glycogene;glycosyltransferase", "function": "Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, beta-D-Gal-(1->4)-beta-D-GlcNAc-) glycan attached to glycolipids and N- or O-linked glycoproteins. Fucosylates distal type 2 LacNAc and its fucosylated (H-type 2 LacNAc) and sialylated (sialyl-type 2 LacNAc) derivatives to form Lewis x (Lex) (CD15) and Lewis y (Ley) antigenic epitopes involved in cell adhesion and differentiation (By similarity). Generates Lex epitopes in the brain, presumably playing a role in the maintenance of neuronal stemness and neurite outgrowth in progenitor neural cells (By similarity). Fucosylates the internal type 2 LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (By similarity). Can also modify milk oligosaccharides in particular type 2 tetrasaccharide LNnT (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.152", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0032588 trans-Golgi network membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0000271 polysaccharide biosynthetic process;GO:0006688 glycosphingolipid biosynthetic process;GO:0010976 positive regulation of neuron projection development;GO:0006493 protein O-linked glycosylation;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9JIG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9JJV8-1", "uniprot_id": [ { "id": "BCL2_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9JJV8", "type": "external" } ], "mass": 26491.0, "length": 236, "protein_name": "Apoptosis regulator Bcl-2", "gene_name": "BCL2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BCL2", "gene_names_refseq": "", "protein_names_uniprotkb": "Apoptosis regulator Bcl-2", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "10973819;11181062", "class_list": "", "function": "Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0002020 protease binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0031965 nuclear membrane;GO:0043209 myelin sheath;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0002931 response to ischemia;GO:0035094 response to nicotine;GO:0051607 defense response to virus;GO:0051881 regulation of mitochondrial membrane potential;GO:0051384 response to glucocorticoid", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9JJV8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9JK82-1", "uniprot_id": [ { "id": "EXT1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9JK82", "type": "external" } ], "mass": 86189.0, "length": 746, "protein_name": "Exostosin-1", "gene_name": "EXT1", "organism": "Hamster", "refseq_name": "exostosin-1", "refseq_ac": [ { "id": "NP_001233696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233696", "type": "external" } ], "gene_names_uniprotkb": "EXT1", "gene_names_refseq": "Ext1", "protein_names_uniprotkb": "Exostosin-1; 2.4.1.225; Heparan sulfate copolymerase; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase", "protein_names_refseq": "Heparan sulfate copolymerase; Multiple exostoses protein 1 homolog; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; exostoses (multiple) 1; exostosin 1; exostosin-1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689334)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10864928", "class_list": "glycogene;glycosyltransferase", "function": "##Evidence-Data-START## Transcript exon combination :: AF252858.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04275174, SAMN04275175 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF252858.1., [RefSeq]; Glycosyltransferase forming with EXT2 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.225", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:1902494 catalytic complex", "go_biological_process": "GO:0000271 polysaccharide biosynthetic process;GO:0001503 ossification;GO:0006024 glycosaminoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9JK82-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000010000000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9QYM7-1", "uniprot_id": [ { "id": "XPF_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9QYM7", "type": "external" } ], "mass": 103187.0, "length": 913, "protein_name": "DNA repair endonuclease XPF", "gene_name": "ERCC4", "organism": "Hamster", "refseq_name": "DNA repair endonuclease XPF", "refseq_ac": [ { "id": "NP_001230961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230961", "type": "external" } ], "gene_names_uniprotkb": "ERCC4", "gene_names_refseq": "Ercc4; Xpf", "protein_names_uniprotkb": "DNA repair endonuclease XPF; 3.1.-.-; DNA excision repair protein ERCC-4", "protein_names_refseq": "DNA excision repair protein ERCC-4; DNA repair endonuclease XPF; excision repair cross-complementation group 4; excision repair cross-complementing rodent repair deficiency, complementation group 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100689044)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0003684 damaged DNA binding;GO:0001094 TFIID-class transcription factor complex binding;GO:0003697 single-stranded DNA binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0000110 nucleotide-excision repair factor 1 complex;GO:0070522 ERCC4-ERCC1 complex;GO:0005634 nucleus;GO:0016604 nuclear body;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0032205 negative regulation of telomere maintenance;GO:0061819 telomeric DNA-containing double minutes formation;GO:1905765 negative regulation of protection from non-homologous end joining at telomere;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9QYM7-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9WU47-1", "uniprot_id": [ { "id": "B3GA3_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9WU47", "type": "external" } ], "mass": 37095.0, "length": 335, "protein_name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "gene_name": "B3GAT3", "organism": "Hamster", "refseq_name": "galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "refseq_ac": [ { "id": "NP_001233613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233613", "type": "external" } ], "gene_names_uniprotkb": "B3GAT3", "gene_names_refseq": "B3gat3; GlcUAT-I; Glcat-i", "protein_names_uniprotkb": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3; 2.4.1.135; Beta-1,3-glucuronyltransferase 3; GlcAT-I; GlcUAT-I; Glucuronosyltransferase I; UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase", "protein_names_refseq": "UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase; beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I); galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3; similar to Homo sapiens glucuronyltransferase I encoded by GenBank Accession Number AB009598", "tax_id": 10029, "disease": "", "pathway": " (cge:100689419)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10075678", "class_list": "", "function": "Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Highest activity seen with Gal-beta-1,3-Gal-beta-O-R (where R=naphthalenemethanol or benzyl alcohol). Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.135", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.135", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0015020 glucuronosyltransferase activity;GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0090316 positive regulation of intracellular protein transport;GO:0005975 carbohydrate metabolic process;GO:0043085 positive regulation of catalytic activity;GO:0006024 glycosaminoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9WU47-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9WV24-1", "uniprot_id": [ { "id": "B2MG_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9WV24", "type": "external" } ], "mass": 13788.0, "length": 119, "protein_name": "Beta-2-microglobulin", "gene_name": "B2M", "organism": "Hamster", "refseq_name": "beta-2-microglobulin precursor", "refseq_ac": [ { "id": "NP_001233603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233603", "type": "external" } ], "gene_names_uniprotkb": "B2M", "gene_names_refseq": "B2m", "protein_names_uniprotkb": "Beta-2-microglobulin", "protein_names_refseq": "beta 2-m; beta-2-microglobulin precursor", "tax_id": 10029, "disease": "", "pathway": " (cge:100689409)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005794 Golgi apparatus;GO:0009897 external side of plasma membrane;GO:0042612 MHC class I protein complex;GO:1990712 HFE-transferrin receptor complex", "go_biological_process": "GO:0006955 immune response;GO:0007611 learning or memory;GO:0051289 protein homotetramerization;GO:1990000 amyloid fibril formation;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9WV24-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9WV82-1", "uniprot_id": [ { "id": "TLR4_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9WV82", "type": "external" } ], "mass": 96278.0, "length": 838, "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "organism": "Hamster", "refseq_name": "toll-like receptor 4 precursor", "refseq_ac": [ { "id": "NP_001233691", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233691", "type": "external" } ], "gene_names_uniprotkb": "TLR4", "gene_names_refseq": "Tlr4", "protein_names_uniprotkb": "Toll-like receptor 4", "protein_names_refseq": "toll-like receptor 4 precursor", "tax_id": 10029, "disease": "", "pathway": " (cge:100689329)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10683379", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF153676.1, JI881679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04275174, SAMN04275175 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF153676.1., [RefSeq]; Transmembrane receptor that functions as a pattern recognition receptor recognizing pathogen- and damage-associated molecular patterns (PAMPs and DAMPs) to induce innate immune responses via downstream signaling pathways. At the plasma membrane, cooperates with LY96 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni(2+). Mechanistically, acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Alternatively, CD14-mediated TLR4 internalization via endocytosis is associated with the initiation of a MYD88-independent signaling via the TICAM1-TBK1-IRF3 axis leading to type I interferon production. In addition to the secretion of proinflammatory cytokines, initiates the activation of NLRP3 inflammasome and formation of a positive feedback loop between autophagy and NF-kappa-B signaling cascade. In complex with TLR6, promotes inflammation in monocytes/macrophages by associating with TLR6 and the receptor CD86. Upon ligand binding, such as oxLDL or amyloid-beta 42, the TLR4:TLR6 complex is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway. In myeloid dendritic cells, vesicular stomatitis virus glycoprotein G but not LPS promotes the activation of IRF7, leading to type I IFN production in a CD14-dependent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 11, "predicted_n_glycosites": 11, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0043032 positive regulation of macrophage activation;GO:0032700 negative regulation of interleukin-17 production;GO:0002246 wound healing involved in inflammatory response;GO:1904466 positive regulation of matrix metallopeptidase secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9WV82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Z297-1", "uniprot_id": [ { "id": "PEA15_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9Z297", "type": "external" } ], "mass": 15040.0, "length": 130, "protein_name": "Astrocytic phosphoprotein PEA-15", "gene_name": "PEA15", "organism": "Hamster", "refseq_name": "astrocytic phosphoprotein PEA-15", "refseq_ac": [ { "id": "NP_001231780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231780", "type": "external" } ], "gene_names_uniprotkb": "PEA15", "gene_names_refseq": "PEA-15; Pea15", "protein_names_uniprotkb": "Astrocytic phosphoprotein PEA-15; 15 kDa phosphoprotein enriched in astrocytes", "protein_names_refseq": "15 kDa phosphoprotein enriched in astrocytes; astrocytic phosphoprotein PEA-15; phosphoprotein enriched in astrocytes 15A", "tax_id": 10029, "disease": "", "pathway": " (cge:100736554)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10982386;12456656;12796492;14506247;9852038", "class_list": "", "function": "Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 14, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0000165 MAPK cascade;GO:0006915 apoptotic process;GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0046325 negative regulation of D-glucose import", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9Z297-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Z2Z7-1", "uniprot_id": [ { "id": "PGPS1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9Z2Z7", "type": "external" } ], "mass": 62369.0, "length": 553, "protein_name": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial", "gene_name": "PGS1", "organism": "Hamster", "refseq_name": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial", "refseq_ac": [ { "id": "NP_001233637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233637", "type": "external" } ], "gene_names_uniprotkb": "PGS1", "gene_names_refseq": "Pgs1", "protein_names_uniprotkb": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial; 2.7.8.5; PGP synthase 1; Phosphatidylglycerophosphate synthase 1", "protein_names_refseq": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial; PGP synthase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689449)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11171073;9880566", "class_list": "", "function": "Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005509 calcium ion binding;GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0008654 phospholipid biosynthetic process;GO:0006655 phosphatidylglycerol biosynthetic process;GO:0032049 cardiolipin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9Z2Z7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K169-1", "uniprot_id": [ { "id": "A0A9J7K169_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K169", "type": "external" } ], "mass": 75717.0, "length": 674, "protein_name": "Rab proteins geranylgeranyltransferase component A 1", "gene_name": "Chm", "organism": "Hamster", "refseq_name": "rab proteins geranylgeranyltransferase component A 1 isoform X2", "refseq_ac": [ { "id": "XP_027288811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288811", "type": "external" } ], "gene_names_uniprotkb": "Chm", "gene_names_refseq": "Chm", "protein_names_uniprotkb": "Rab proteins geranylgeranyltransferase component A 1; Choroideremia protein homolog; Rab escort protein 1", "protein_names_refseq": "rab proteins geranylgeranyltransferase component A 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763141)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane., [UniProtKB, UniProtKB, UniProtKB]; Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005968 Rab-protein geranylgeranyltransferase complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007264 small GTPase-mediated signal transduction;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K169-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYN1-1", "uniprot_id": [ { "id": "A0A9J7JYN1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYN1", "type": "external" } ], "mass": 89818.0, "length": 806, "protein_name": "E3 ubiquitin-protein ligase TRIM9", "gene_name": "LOC100765785", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase TRIM9 isoform X2", "refseq_ac": [ { "id": "XP_035301167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301167", "type": "external" } ], "gene_names_uniprotkb": "LOC100765785", "gene_names_refseq": "LOC100765785", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM9; 2.3.2.27; RING-type E3 ubiquitin transferase TRIM9; Tripartite motif-containing protein 9", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM9 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765785)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030425 dendrite;GO:0008021 synaptic vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYH7-1", "uniprot_id": [ { "id": "A0A9J7JYH7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYH7", "type": "external" } ], "mass": 64225.0, "length": 575, "protein_name": "Signal recognition particle 54 kDa protein", "gene_name": "Srp54", "organism": "Hamster", "refseq_name": "signal recognition particle 54 kDa protein isoform X5", "refseq_ac": [ { "id": "XP_035300953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300953", "type": "external" } ], "gene_names_uniprotkb": "Srp54", "gene_names_refseq": "Srp54", "protein_names_uniprotkb": "Signal recognition particle 54 kDa protein; 3.6.5.-", "protein_names_refseq": "signal recognition particle 54 kDa protein isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100756776)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER. Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA. Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0030942 endoplasmic reticulum signal peptide binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008312 7S RNA binding;GO:0043021 ribonucleoprotein complex binding", "go_cellular_component": "GO:0005786 signal recognition particle, endoplasmic reticulum targeting;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0030851 granulocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K162-1", "uniprot_id": [ { "id": "A0A9J7K162_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K162", "type": "external" } ], "mass": 56513.0, "length": 494, "protein_name": "Cytochrome P450", "gene_name": "LOC100772358", "organism": "Hamster", "refseq_name": "cytochrome P450 2A3 isoform X2", "refseq_ac": [ { "id": "XP_027286208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286208", "type": "external" } ], "gene_names_uniprotkb": "LOC100772358", "gene_names_refseq": "LOC100772358", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2A3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772358)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway;GO:0009804 coumarin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K162-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1U6-1", "uniprot_id": [ { "id": "A0A9J7K1U6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1U6", "type": "external" } ], "mass": 14382.0, "length": 137, "protein_name": "2-iminobutanoate/2-iminopropanoate deaminase", "gene_name": "Rida", "organism": "Hamster", "refseq_name": "2-iminobutanoate/2-iminopropanoate deaminase isoform X1", "refseq_ac": [ { "id": "XP_007642774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642774", "type": "external" } ], "gene_names_uniprotkb": "Rida", "gene_names_refseq": "Rida", "protein_names_uniprotkb": "2-iminobutanoate/2-iminopropanoate deaminase; 3.5.99.10; Reactive intermediate imine deaminase A homolog; Translation inhibitor L-PSP ribonuclease", "protein_names_refseq": "2-iminobutanoate/2-iminopropanoate deaminase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754697)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 171 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614029.1) and transcript sequence (JI875327.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage., [UniProtKB, UniProtKB]; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.99.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.99.10", "type": "external" } ], "go_molecular_function": "GO:0019239 deaminase activity;GO:0003723 RNA binding;GO:0120241 2-iminobutanoate/2-iminopropanoate deaminase", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005634 nucleus;GO:0005777 peroxisome", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0010629 negative regulation of gene expression;GO:0010608 post-transcriptional regulation of gene expression;GO:0080090 regulation of primary metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1U6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVN7-1", "uniprot_id": [ { "id": "A0A9J7JVN7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVN7", "type": "external" } ], "mass": 7047.0, "length": 62, "protein_name": "Small nuclear ribonucleoprotein G", "gene_name": "LOC107978645", "organism": "Hamster", "refseq_name": "small nuclear ribonucleoprotein G-like", "refseq_ac": [ { "id": "XP_035297210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297210", "type": "external" } ], "gene_names_uniprotkb": "LOC107978645", "gene_names_refseq": "LOC107978645", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein G; snRNP-G", "protein_names_refseq": "small nuclear ribonucleoprotein G-like", "tax_id": 10029, "disease": "", "pathway": " (cge:107978645)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005829 cytosol;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVN9-1", "uniprot_id": [ { "id": "A0A9J7JVN9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVN9", "type": "external" } ], "mass": 27579.0, "length": 251, "protein_name": "Centromere protein V", "gene_name": "Cenpv", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: centromere protein V isoform X2", "refseq_ac": [ { "id": "XP_027282980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282980", "type": "external" } ], "gene_names_uniprotkb": "Cenpv", "gene_names_refseq": "Cenpv", "protein_names_uniprotkb": "Centromere protein V; Proline-rich protein 6", "protein_names_refseq": "LOW QUALITY PROTEIN: centromere protein V isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761123)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016846 carbon-sulfur lyase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0051233 spindle midzone;GO:0000776 kinetochore", "go_biological_process": "GO:0033044 regulation of chromosome organization;GO:0031508 pericentric heterochromatin formation;GO:0051301 cell division;GO:0032467 positive regulation of cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVN9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVW7-1", "uniprot_id": [ { "id": "A0A9J7JVW7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVW7", "type": "external" } ], "mass": 121230.0, "length": 1110, "protein_name": "Scavenger receptor cysteine-rich domain-containing protein DMBT1", "gene_name": "Dmbt1", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein isoform X2", "refseq_ac": [ { "id": "XP_035297501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297501", "type": "external" } ], "gene_names_uniprotkb": "Dmbt1", "gene_names_refseq": "Dmbt1", "protein_names_uniprotkb": "Scavenger receptor cysteine-rich domain-containing protein DMBT1; Deleted in malignant brain tumors 1 protein; Hensin", "protein_names_refseq": "LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763251)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0030658 transport vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0030154 cell differentiation;GO:0045217 cell-cell junction maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVW7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JVX0-1", "uniprot_id": [ { "id": "A0A9J7JVX0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JVX0", "type": "external" } ], "mass": 51929.0, "length": 465, "protein_name": "Ras GTPase-activating protein-binding protein 1", "gene_name": "G3bp1", "organism": "Hamster", "refseq_name": "ras GTPase-activating protein-binding protein 1 isoform X2", "refseq_ac": [ { "id": "XP_027283250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283250", "type": "external" } ], "gene_names_uniprotkb": "G3bp1", "gene_names_refseq": "G3bp1", "protein_names_uniprotkb": "Ras GTPase-activating protein-binding protein 1; 3.6.4.12; 3.6.4.13", "protein_names_refseq": "ras GTPase-activating protein-binding protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761148)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0043204 perikaryon;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JVX0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXQ6-1", "uniprot_id": [ { "id": "A0A9J7JXQ6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXQ6", "type": "external" } ], "mass": 59621.0, "length": 527, "protein_name": "Hexosaminidase D", "gene_name": "Hexd", "organism": "Hamster", "refseq_name": "hexosaminidase D isoform X1", "refseq_ac": [ { "id": "XP_007652517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652517", "type": "external" } ], "gene_names_uniprotkb": "Hexd", "gene_names_refseq": "Hexd", "protein_names_uniprotkb": "Hexosaminidase D; 3.2.1.52; Beta-N-acetylhexosaminidase; Beta-hexosaminidase D; Hexosaminidase domain-containing protein; N-acetyl-beta-galactosaminidase", "protein_names_refseq": "hexosaminidase D isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773287)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has hexosaminidase activity. Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) from cellular substrates. Has a preference for galactosaminide over glucosaminide substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JW72-1", "uniprot_id": [ { "id": "A0A9J7JW72_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JW72", "type": "external" } ], "mass": 36987.0, "length": 334, "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase", "gene_name": "Rfng", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: beta-1,3-N-acetylglucosaminyltransferase radical fringe isoform X2", "refseq_ac": [ { "id": "XP_027281154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281154", "type": "external" } ], "gene_names_uniprotkb": "Rfng", "gene_names_refseq": "Rfng", "protein_names_uniprotkb": "Beta-1,3-N-acetylglucosaminyltransferase; 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "protein_names_refseq": "LOW QUALITY PROTEIN: beta-1,3-N-acetylglucosaminyltransferase radical fringe isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771257)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.222", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.222", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0007389 pattern specification process;GO:0008593 regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JW72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXX0-1", "uniprot_id": [ { "id": "A0A9J7JXX0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXX0", "type": "external" } ], "mass": 39349.0, "length": 358, "protein_name": "Kynurenine formamidase", "gene_name": "Afmid", "organism": "Hamster", "refseq_name": "kynurenine formamidase isoform X1", "refseq_ac": [ { "id": "XP_007632053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632053", "type": "external" } ], "gene_names_uniprotkb": "Afmid; AFMID", "gene_names_refseq": "Afmid", "protein_names_uniprotkb": "Kynurenine formamidase; 3.5.1.9; Arylformamidase; FKF; KFA; KFase; N-formylkynurenine formamidase", "protein_names_refseq": "kynurenine formamidase isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100773211)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613705.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.9", "type": "external" } ], "go_molecular_function": "GO:0004061 arylformamidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXX0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWG1-1", "uniprot_id": [ { "id": "A0A9J7JWG1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWG1", "type": "external" } ], "mass": 61332.0, "length": 540, "protein_name": "Prostacyclin synthase", "gene_name": "Ptgis", "organism": "Hamster", "refseq_name": "prostacyclin synthase", "refseq_ac": [ { "id": "XP_016831098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831098", "type": "external" } ], "gene_names_uniprotkb": "Ptgis", "gene_names_refseq": "Ptgis", "protein_names_uniprotkb": "Prostacyclin synthase; 4.2.1.152; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; Prostaglandin I2 synthase", "protein_names_refseq": "prostacyclin synthase", "tax_id": 10029, "disease": "", "pathway": " (cge:100757024)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613899.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.152", "type": "external" }, { "id": "5.3.99.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.5", "type": "external" }, { "id": "5.3.99.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.4", "type": "external" } ], "go_molecular_function": "GO:0008116 prostaglandin-I synthase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWJ9-1", "uniprot_id": [ { "id": "A0A9J7JWJ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWJ9", "type": "external" } ], "mass": 101531.0, "length": 932, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Otud7a", "organism": "Hamster", "refseq_name": "OTU domain-containing protein 7A isoform X2", "refseq_ac": [ { "id": "XP_035298363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298363", "type": "external" } ], "gene_names_uniprotkb": "Otud7a", "gene_names_refseq": "Otud7a", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "OTU domain-containing protein 7A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763787)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070536 protein K63-linked deubiquitination;GO:0071108 protein K48-linked deubiquitination;GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0035871 protein K11-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWM7-1", "uniprot_id": [ { "id": "A0A9J7JWM7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWM7", "type": "external" } ], "mass": 550139.0, "length": 4991, "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "Kmt2c", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C isoform X2", "refseq_ac": [ { "id": "XP_027284324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284324", "type": "external" } ], "gene_names_uniprotkb": "Kmt2c", "gene_names_refseq": "Kmt2c", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase 2C; 2.1.1.364", "protein_names_refseq": "LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767367)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2D in enriching H3K4me1 mark on primed and active enhancer elements., [UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0016746 acyltransferase activity;GO:0140945 histone H3K4 monomethyltransferase activity", "go_cellular_component": "GO:0044666 MLL3/4 complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWM7-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWT2-1", "uniprot_id": [ { "id": "A0A9J7JWT2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWT2", "type": "external" } ], "mass": 173142.0, "length": 1589, "protein_name": "Laminin subunit gamma-3", "gene_name": "Lamc3", "organism": "Hamster", "refseq_name": "laminin subunit gamma-3 isoform X2", "refseq_ac": [ { "id": "XP_027279667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279667", "type": "external" } ], "gene_names_uniprotkb": "Lamc3", "gene_names_refseq": "Lamc3", "protein_names_uniprotkb": "Laminin subunit gamma-3; Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma", "protein_names_refseq": "laminin subunit gamma-3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751974)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0009887 animal organ morphogenesis;GO:0007411 axon guidance;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWT2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWX6-1", "uniprot_id": [ { "id": "A0A9J7JWX6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWX6", "type": "external" } ], "mass": 40294.0, "length": 372, "protein_name": "Formylglycine-generating enzyme", "gene_name": "Sumf1", "organism": "Hamster", "refseq_name": "formylglycine-generating enzyme isoform X2", "refseq_ac": [ { "id": "XP_027284812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284812", "type": "external" } ], "gene_names_uniprotkb": "Sumf1", "gene_names_refseq": "Sumf1", "protein_names_uniprotkb": "Formylglycine-generating enzyme; 1.8.3.7; C-alpha-formylglycine-generating enzyme 1; Sulfatase-modifying factor 1", "protein_names_refseq": "formylglycine-generating enzyme isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100766494)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.7", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0120147 formylglycine-generating oxidase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0043687 post-translational protein modification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JWZ9-1", "uniprot_id": [ { "id": "A0A9J7JWZ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JWZ9", "type": "external" } ], "mass": 80252.0, "length": 721, "protein_name": "Ubiquitin-like modifier-activating enzyme ATG7", "gene_name": "LOC100754902", "organism": "Hamster", "refseq_name": "ubiquitin-like modifier-activating enzyme ATG7 isoform X4", "refseq_ac": [ { "id": "XP_027284934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284934", "type": "external" } ], "gene_names_uniprotkb": "LOC100754902", "gene_names_refseq": "LOC100754902", "protein_names_uniprotkb": "Ubiquitin-like modifier-activating enzyme ATG7; Autophagy-related protein 7", "protein_names_refseq": "ubiquitin-like modifier-activating enzyme ATG7 isoform X4", "tax_id": 10029, "disease": "", "pathway": " (cge:100754902)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019778 Atg12 activating enzyme activity;GO:0019779 Atg8 activating enzyme activity", "go_cellular_component": "GO:0000407 phagophore assembly site", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0048511 rhythmic process;GO:0000422 autophagy of mitochondrion;GO:0010667 negative regulation of cardiac muscle cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JWZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JX17-1", "uniprot_id": [ { "id": "A0A9J7JX17_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JX17", "type": "external" } ], "mass": 38608.0, "length": 357, "protein_name": "Ubiquitin-conjugating enzyme E2 Z", "gene_name": "Ube2z", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 Z isoform X2", "refseq_ac": [ { "id": "XP_027280037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280037", "type": "external" } ], "gene_names_uniprotkb": "Ube2z", "gene_names_refseq": "Ube2z", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 Z; 2.3.2.23; E2 ubiquitin-conjugating enzyme Z; Uba6-specific E2 conjugating enzyme 1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z", "protein_names_refseq": "LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 Z isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753214)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004869 cysteine-type endopeptidase inhibitor activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JX17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXA2-1", "uniprot_id": [ { "id": "A0A9J7JXA2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXA2", "type": "external" } ], "mass": 29148.0, "length": 268, "protein_name": "C-X-C motif chemokine 16", "gene_name": "Cxcl16", "organism": "Hamster", "refseq_name": "C-X-C motif chemokine 16 isoform X1", "refseq_ac": [ { "id": "XP_007606908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606908", "type": "external" } ], "gene_names_uniprotkb": "Cxcl16", "gene_names_refseq": "Cxcl16", "protein_names_uniprotkb": "C-X-C motif chemokine 16; Transmembrane chemokine CXCL16", "protein_names_refseq": "C-X-C motif chemokine 16 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751127)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 549 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) and transcript sequence (IACG01125823.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005041 low-density lipoprotein particle receptor activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0030307 positive regulation of cell growth;GO:0030335 positive regulation of cell migration;GO:0034612 response to tumor necrosis factor;GO:0006898 receptor-mediated endocytosis;GO:0010818 T cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXA2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXD7-1", "uniprot_id": [ { "id": "A0A9J7JXD7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXD7", "type": "external" } ], "mass": 32258.0, "length": 289, "protein_name": "Enoyl-CoA delta isomerase 1, mitochondrial", "gene_name": "Eci1", "organism": "Hamster", "refseq_name": "enoyl-CoA delta isomerase 1, mitochondrial isoform X2", "refseq_ac": [ { "id": "XP_027280715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280715", "type": "external" } ], "gene_names_uniprotkb": "Eci1", "gene_names_refseq": "Eci1", "protein_names_uniprotkb": "Enoyl-CoA delta isomerase 1, mitochondrial; 3,2-trans-enoyl-CoA isomerase; 5.3.3.8; Delta(3),Delta(2)-enoyl-CoA isomerase; Dodecenoyl-CoA isomerase", "protein_names_refseq": "enoyl-CoA delta isomerase 1, mitochondrial isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774222)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key enzyme of fatty acid beta-oxidation. Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs. The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" }, { "id": "4.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.17", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" } ], "go_molecular_function": "GO:0004165 delta(3)-delta(2)-enoyl-CoA isomerase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXD7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXM2-1", "uniprot_id": [ { "id": "A0A9J7JXM2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXM2", "type": "external" } ], "mass": 169002.0, "length": 1505, "protein_name": "DDB1- and CUL4-associated factor 1", "gene_name": "Dcaf1", "organism": "Hamster", "refseq_name": "DDB1- and CUL4-associated factor 1 isoform X1", "refseq_ac": [ { "id": "XP_007639277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639277", "type": "external" } ], "gene_names_uniprotkb": "Dcaf1", "gene_names_refseq": "Dcaf1", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 1; 2.7.11.1; Serine/threonine-protein kinase VPRBP", "protein_names_refseq": "DDB1- and CUL4-associated factor 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768333)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613788.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0030331 nuclear estrogen receptor binding;GO:1990244 histone H2AT120 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXM2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXR7-1", "uniprot_id": [ { "id": "A0A9J7JXR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXR7", "type": "external" } ], "mass": 54168.0, "length": 481, "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "Dus1l", "organism": "Hamster", "refseq_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "refseq_ac": [ { "id": "XP_003496955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496955", "type": "external" } ], "gene_names_uniprotkb": "Dus1l", "gene_names_refseq": "Dus1l", "protein_names_uniprotkb": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like; 1.3.1.88; tRNA-dihydrouridine synthase 1-like", "protein_names_refseq": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100770971)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003496955.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U16 and U17 in cytoplasmic tRNAs. Affects the level of some mature tRNA and thereby the total cellular translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.88", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.88", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0017150 tRNA dihydrouridine synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXS9-1", "uniprot_id": [ { "id": "A0A9J7JXS9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXS9", "type": "external" } ], "mass": 22166.0, "length": 206, "protein_name": "Flavin reductase (NADPH)", "gene_name": "Blvrb", "organism": "Hamster", "refseq_name": "flavin reductase (NADPH) isoform X2", "refseq_ac": [ { "id": "XP_027286240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286240", "type": "external" } ], "gene_names_uniprotkb": "Blvrb", "gene_names_refseq": "Blvrb", "protein_names_uniprotkb": "Flavin reductase (NADPH); 1.5.1.30; Biliverdin reductase B; Biliverdin-IX beta-reductase; NADPH-dependent diaphorase; NADPH-flavin reductase; S-nitroso-CoA-assisted nitrosyltransferase", "protein_names_refseq": "flavin reductase (NADPH) isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768929)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.1.30", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.30", "type": "external" } ], "go_molecular_function": "GO:0035605 peptidyl-cysteine S-nitrosylase activity;GO:0004074 biliverdin reductase [NAD(P)H] activity;GO:0042602 riboflavin reductase (NADPH) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXU5-1", "uniprot_id": [ { "id": "A0A9J7JXU5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXU5", "type": "external" } ], "mass": 90468.0, "length": 813, "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "Acsbg1", "organism": "Hamster", "refseq_name": "long-chain-fatty-acid--CoA ligase ACSBG1", "refseq_ac": [ { "id": "XP_035299721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299721", "type": "external" } ], "gene_names_uniprotkb": "Acsbg1", "gene_names_refseq": "Acsbg1", "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase ACSBG1; 6.2.1.3; Acyl-CoA synthetase bubblegum family member 1; Gonadotropin-regulated long chain acyl CoA synthetase", "protein_names_refseq": "long-chain-fatty-acid--CoA ligase ACSBG1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754767)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 20% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613669.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004467 long-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXU5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JXU9-1", "uniprot_id": [ { "id": "A0A9J7JXU9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JXU9", "type": "external" } ], "mass": 108241.0, "length": 980, "protein_name": "Signal recognition particle receptor subunit beta", "gene_name": "LOC100767241", "organism": "Hamster", "refseq_name": "serotransferrin", "refseq_ac": [ { "id": "XP_035300124", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300124", "type": "external" } ], "gene_names_uniprotkb": "LOC100767241", "gene_names_refseq": "LOC100767241", "protein_names_uniprotkb": "Signal recognition particle receptor subunit beta", "protein_names_refseq": "serotransferrin", "tax_id": 10029, "disease": "", "pathway": " (cge:100767241)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JXU9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JY26-1", "uniprot_id": [ { "id": "A0A9J7JY26_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JY26", "type": "external" } ], "mass": 39389.0, "length": 375, "protein_name": "Vasodilator-stimulated phosphoprotein", "gene_name": "Vasp", "organism": "Hamster", "refseq_name": "vasodilator-stimulated phosphoprotein isoform X2", "refseq_ac": [ { "id": "XP_027286732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286732", "type": "external" } ], "gene_names_uniprotkb": "Vasp", "gene_names_refseq": "Vasp", "protein_names_uniprotkb": "Vasodilator-stimulated phosphoprotein", "protein_names_refseq": "vasodilator-stimulated phosphoprotein isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756352)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0017124 SH3 domain binding;GO:0005522 profilin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005923 bicellular tight junction;GO:0005925 focal adhesion;GO:0031258 lamellipodium membrane", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0008154 actin polymerization or depolymerization;GO:0001843 neural tube closure;GO:0030838 positive regulation of actin filament polymerization;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JY26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYM0-1", "uniprot_id": [ { "id": "A0A9J7JYM0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYM0", "type": "external" } ], "mass": 55176.0, "length": 483, "protein_name": "Vitronectin", "gene_name": "Vtn", "organism": "Hamster", "refseq_name": "vitronectin", "refseq_ac": [ { "id": "XP_027282370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282370", "type": "external" } ], "gene_names_uniprotkb": "Vtn", "gene_names_refseq": "Vtn", "protein_names_uniprotkb": "Vitronectin; S-protein; Serum-spreading factor", "protein_names_refseq": "vitronectin", "tax_id": 10029, "disease": "", "pathway": " (cge:100767624)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0005044 scavenger receptor activity;GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYU8-1", "uniprot_id": [ { "id": "A0A9J7JYU8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYU8", "type": "external" } ], "mass": 42771.0, "length": 369, "protein_name": "Ubl carboxyl-terminal hydrolase 18", "gene_name": "Usp18", "organism": "Hamster", "refseq_name": "ubl carboxyl-terminal hydrolase 18", "refseq_ac": [ { "id": "XP_027285143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285143", "type": "external" } ], "gene_names_uniprotkb": "Usp18", "gene_names_refseq": "Usp18", "protein_names_uniprotkb": "Ubl carboxyl-terminal hydrolase 18; 3.4.19.12; ISG15-specific-processing protease; Ubl thioesterase 18", "protein_names_refseq": "ubl carboxyl-terminal hydrolase 18", "tax_id": 10029, "disease": "", "pathway": " (cge:100753049)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interferon-induced ISG15-specific protease that plays a crucial role for maintaining a proper balance of ISG15-conjugated proteins in cells. Regulates protein ISGylation by efficiently cleaving ISG15 conjugates linked via isopeptide bonds. Regulates T-cell activation and T-helper 17 (Th17) cell differentiation by deubiquitinating TAK1, likely to keep TAK1-TAB complexes in steady conditions. In turn, restricts activation of NF-kappa-B, NFAT, and JNK as well as expression of IL2 in T-cells after TCR activation. Acts as a molecular adapter with USP20 to promote innate antiviral response through deubiquitinating STING1. Involved also in the negative regulation of the inflammatory response triggered by type I interferon. Upon recruitment by STAT2 to the type I interferon receptor subunit IFNAR2 interferes with the assembly of the ternary interferon-IFNAR1-IFNAR2 complex and acts as a negative regulator of the type I interferon signaling pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0019785 ISG15-specific peptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0051707 response to other organism;GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JYZ1-1", "uniprot_id": [ { "id": "A0A9J7JYZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JYZ1", "type": "external" } ], "mass": 78209.0, "length": 694, "protein_name": "Follicle-stimulating hormone receptor", "gene_name": "Fshr", "organism": "Hamster", "refseq_name": "follicle-stimulating hormone receptor isoform X1", "refseq_ac": [ { "id": "XP_035301626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301626", "type": "external" } ], "gene_names_uniprotkb": "Fshr; FSHR", "gene_names_refseq": "Fshr", "protein_names_uniprotkb": "Follicle-stimulating hormone receptor; Follitropin receptor", "protein_names_refseq": "follicle-stimulating hormone receptor isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100769953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004963 follicle-stimulating hormone receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008584 male gonad development;GO:0009755 hormone-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JYZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZ20-1", "uniprot_id": [ { "id": "A0A9J7JZ20_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZ20", "type": "external" } ], "mass": 30647.0, "length": 276, "protein_name": "CD70 antigen", "gene_name": "LOC113835853", "organism": "Hamster", "refseq_name": "CD70 antigen-like", "refseq_ac": [ { "id": "XP_035301739", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301739", "type": "external" } ], "gene_names_uniprotkb": "LOC113835853", "gene_names_refseq": "LOC113835853", "protein_names_uniprotkb": "CD70 antigen; CD27 ligand; Tumor necrosis factor ligand superfamily member 7", "protein_names_refseq": "CD70 antigen-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113835853)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 50% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0048018 receptor ligand activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0006955 immune response;GO:0042110 T cell activation;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0046651 lymphocyte proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZ20-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZ26-1", "uniprot_id": [ { "id": "A0A9J7JZ26_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZ26", "type": "external" } ], "mass": 82175.0, "length": 735, "protein_name": "Glycine--tRNA ligase", "gene_name": "Gars1", "organism": "Hamster", "refseq_name": "glycine--tRNA ligase isoform X2", "refseq_ac": [ { "id": "XP_027285483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285483", "type": "external" } ], "gene_names_uniprotkb": "Gars1", "gene_names_refseq": "Gars1", "protein_names_uniprotkb": "Glycine--tRNA ligase; 6.1.1.14; Diadenosine tetraphosphate synthetase; Glycyl-tRNA synthetase 1", "protein_names_refseq": "glycine--tRNA ligase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751073)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.14", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016740 transferase activity;GO:0004820 glycine-tRNA ligase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005739 mitochondrion;GO:0030424 axon", "go_biological_process": "GO:0070150 mitochondrial glycyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZ26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZ65-1", "uniprot_id": [ { "id": "A0A9J7JZ65_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZ65", "type": "external" } ], "mass": 123291.0, "length": 1073, "protein_name": "Guanylate cyclase", "gene_name": "Gucy2c", "organism": "Hamster", "refseq_name": "heat-stable enterotoxin receptor isoform X2", "refseq_ac": [ { "id": "XP_027285710", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285710", "type": "external" } ], "gene_names_uniprotkb": "Gucy2c", "gene_names_refseq": "Gucy2c", "protein_names_uniprotkb": "Guanylate cyclase; 4.6.1.2", "protein_names_refseq": "heat-stable enterotoxin receptor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757969)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.2", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0004383 guanylate cyclase activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007168 receptor guanylyl cyclase signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZ65-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZG7-1", "uniprot_id": [ { "id": "A0A9J7JZG7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZG7", "type": "external" } ], "mass": 56231.0, "length": 491, "protein_name": "Cytochrome P450", "gene_name": "LOC100762876", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1", "refseq_ac": [ { "id": "XP_027286203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286203", "type": "external" } ], "gene_names_uniprotkb": "LOC100762876", "gene_names_refseq": "LOC100762876", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762876)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027286203.1. COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZG7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZR7-1", "uniprot_id": [ { "id": "A0A9J7JZR7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZR7", "type": "external" } ], "mass": 66637.0, "length": 593, "protein_name": "Glutamate decarboxylase 1", "gene_name": "Gad1", "organism": "Hamster", "refseq_name": "glutamate decarboxylase 1 isoform X1", "refseq_ac": [ { "id": "XP_035302605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302605", "type": "external" } ], "gene_names_uniprotkb": "Gad1", "gene_names_refseq": "Gad1", "protein_names_uniprotkb": "Glutamate decarboxylase 1; 4.1.1.15; 67 kDa glutamic acid decarboxylase; Glutamate decarboxylase 67 kDa isoform", "protein_names_refseq": "glutamate decarboxylase 1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100765882)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.15", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004351 glutamate decarboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0048786 presynaptic active zone", "go_biological_process": "GO:0035176 social behavior;GO:0009449 gamma-aminobutyric acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZS0-1", "uniprot_id": [ { "id": "A0A9J7JZS0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZS0", "type": "external" } ], "mass": 72290.0, "length": 631, "protein_name": "Dual specificity tyrosine-phosphorylation-regulated kinase 4", "gene_name": "Dyrk4", "organism": "Hamster", "refseq_name": "dual specificity tyrosine-phosphorylation-regulated kinase 4", "refseq_ac": [ { "id": "XP_003496079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496079", "type": "external" } ], "gene_names_uniprotkb": "Dyrk4", "gene_names_refseq": "Dyrk4", "protein_names_uniprotkb": "Dual specificity tyrosine-phosphorylation-regulated kinase 4; 2.7.12.1", "protein_names_refseq": "dual specificity tyrosine-phosphorylation-regulated kinase 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100772985)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613610.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Possible non-essential role in spermiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZS0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZS9-1", "uniprot_id": [ { "id": "A0A9J7JZS9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZS9", "type": "external" } ], "mass": 75977.0, "length": 674, "protein_name": "Xaa-Pro aminopeptidase 2", "gene_name": "Xpnpep2", "organism": "Hamster", "refseq_name": "xaa-Pro aminopeptidase 2 isoform X2", "refseq_ac": [ { "id": "XP_027289312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289312", "type": "external" } ], "gene_names_uniprotkb": "Xpnpep2", "gene_names_refseq": "Xpnpep2", "protein_names_uniprotkb": "Xaa-Pro aminopeptidase 2; 3.4.11.9; Membrane-bound aminopeptidase P; X-prolyl aminopeptidase 2", "protein_names_refseq": "xaa-Pro aminopeptidase 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774553)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZV4-1", "uniprot_id": [ { "id": "A0A9J7JZV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZV4", "type": "external" } ], "mass": 98004.0, "length": 907, "protein_name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3", "gene_name": "Agap3", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X2", "refseq_ac": [ { "id": "XP_027284237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284237", "type": "external" } ], "gene_names_uniprotkb": "Agap3", "gene_names_refseq": "Agap3", "protein_names_uniprotkb": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3; CRAM-associated GTPase; Centaurin-gamma-3; MR1-interacting protein", "protein_names_refseq": "LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769383)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTPase-activating protein for the ADP ribosylation factor family. GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZW3-1", "uniprot_id": [ { "id": "A0A9J7JZW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZW3", "type": "external" } ], "mass": 155226.0, "length": 1423, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 13", "gene_name": "Adamts13", "organism": "Hamster", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 13", "refseq_ac": [ { "id": "XP_035302827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302827", "type": "external" } ], "gene_names_uniprotkb": "Adamts13", "gene_names_refseq": "Adamts13", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 13; 3.4.24.87; von Willebrand factor-cleaving protease", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 13", "tax_id": 10029, "disease": "", "pathway": " (cge:100770010)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0007596 blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZW3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7JZX3-1", "uniprot_id": [ { "id": "A0A9J7JZX3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7JZX3", "type": "external" } ], "mass": 10647.0, "length": 95, "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "LOC103162414", "organism": "Hamster", "refseq_name": "phospholemman", "refseq_ac": [ { "id": "XP_027286908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286908", "type": "external" } ], "gene_names_uniprotkb": "LOC103162414", "gene_names_refseq": "LOC103162414", "protein_names_uniprotkb": "FXYD domain-containing ion transport regulator", "protein_names_refseq": "phospholemman", "tax_id": 10029, "disease": "", "pathway": " (cge:103162414)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005901 caveola;GO:0030315 T-tubule", "go_biological_process": "GO:0006813 potassium ion transport;GO:0006814 sodium ion transport;GO:0043269 regulation of monoatomic ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7JZX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K015-1", "uniprot_id": [ { "id": "A0A9J7K015_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K015", "type": "external" } ], "mass": 87970.0, "length": 814, "protein_name": "Cadherin-22", "gene_name": "Cdh22", "organism": "Hamster", "refseq_name": "cadherin-22 isoform X2", "refseq_ac": [ { "id": "XP_035303063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303063", "type": "external" } ], "gene_names_uniprotkb": "Cdh22", "gene_names_refseq": "Cdh22", "protein_names_uniprotkb": "Cadherin-22; Pituitary and brain cadherin", "protein_names_refseq": "cadherin-22 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767839)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0016342 catenin complex", "go_biological_process": "GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034332 adherens junction organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K015-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K016-1", "uniprot_id": [ { "id": "A0A9J7K016_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K016", "type": "external" } ], "mass": 103763.0, "length": 931, "protein_name": "DNA ligase", "gene_name": "Lig1", "organism": "Hamster", "refseq_name": "DNA ligase 1 isoform X2", "refseq_ac": [ { "id": "XP_027287107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287107", "type": "external" } ], "gene_names_uniprotkb": "Lig1", "gene_names_refseq": "Lig1", "protein_names_uniprotkb": "DNA ligase; 6.5.1.1", "protein_names_refseq": "DNA ligase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767365)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0051301 cell division;GO:1903461 Okazaki fragment processing involved in mitotic DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K016-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K045-1", "uniprot_id": [ { "id": "A0A9J7K045_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K045", "type": "external" } ], "mass": 52532.0, "length": 469, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838332", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_027289897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289897", "type": "external" } ], "gene_names_uniprotkb": "LOC113838332", "gene_names_refseq": "LOC113838332", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838332)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K045-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K066-1", "uniprot_id": [ { "id": "A0A9J7K066_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K066", "type": "external" } ], "mass": 192956.0, "length": 1738, "protein_name": "Gag-Pol polyprotein", "gene_name": "LOC113837013", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113837013", "refseq_ac": [ { "id": "XP_027284603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284603", "type": "external" } ], "gene_names_uniprotkb": "LOC113837013", "gene_names_refseq": "LOC113837013", "protein_names_uniprotkb": "Gag-Pol polyprotein; 2.7.7.49; 3.1.26.4", "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein LOC113837013", "tax_id": 10029, "disease": "", "pathway": " (cge:113837013)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases frameshifts :: corrected 4 indels internal stop codons :: corrected 3 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027284603.1. COMPLETENESS: full length., [RefSeq]; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003964 RNA-directed DNA polymerase activity;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0004523 RNA-DNA hybrid ribonuclease activity;GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006310 DNA recombination;GO:0006508 proteolysis;GO:0019068 virion assembly;GO:0015074 DNA integration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K066-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0D8-1", "uniprot_id": [ { "id": "A0A9J7K0D8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0D8", "type": "external" } ], "mass": 191994.0, "length": 1690, "protein_name": "Lysine-specific demethylase 5A", "gene_name": "Kdm5a", "organism": "Hamster", "refseq_name": "lysine-specific demethylase 5A isoform X2", "refseq_ac": [ { "id": "XP_027285109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285109", "type": "external" } ], "gene_names_uniprotkb": "Kdm5a", "gene_names_refseq": "Kdm5a", "protein_names_uniprotkb": "Lysine-specific demethylase 5A; 1.14.11.67; Histone demethylase JARID1A; Jumonji/ARID domain-containing protein 1A; Retinoblastoma-binding protein 2; [histone H3]-trimethyl-L-lysine(4) demethylase 5A", "protein_names_refseq": "lysine-specific demethylase 5A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757111)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.67", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.67", "type": "external" } ], "go_molecular_function": "GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0D8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0E1-1", "uniprot_id": [ { "id": "A0A9J7K0E1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0E1", "type": "external" } ], "mass": 234754.0, "length": 2108, "protein_name": "Gag-Pol polyprotein", "gene_name": "LOC113833979", "organism": "Hamster", "refseq_name": "uncharacterized protein LOC113833979", "refseq_ac": [ { "id": "XP_035294574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294574", "type": "external" } ], "gene_names_uniprotkb": "LOC113833979", "gene_names_refseq": "LOC113833979", "protein_names_uniprotkb": "Gag-Pol polyprotein; 2.7.7.49; 3.1.26.4", "protein_names_refseq": "uncharacterized protein LOC113833979", "tax_id": 10029, "disease": "", "pathway": " (cge:113833979)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 34% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003964 RNA-directed DNA polymerase activity;GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0004523 RNA-DNA hybrid ribonuclease activity;GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006310 DNA recombination;GO:0006508 proteolysis;GO:0019068 virion assembly;GO:0015074 DNA integration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0E1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0F0-1", "uniprot_id": [ { "id": "A0A9J7K0F0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0F0", "type": "external" } ], "mass": 204068.0, "length": 1754, "protein_name": "Periplakin", "gene_name": "Ppl", "organism": "Hamster", "refseq_name": "periplakin isoform X2", "refseq_ac": [ { "id": "XP_035303560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303560", "type": "external" } ], "gene_names_uniprotkb": "Ppl", "gene_names_refseq": "Ppl", "protein_names_uniprotkb": "Periplakin", "protein_names_refseq": "periplakin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768727)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0045296 cadherin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005882 intermediate filament;GO:0001533 cornified envelope;GO:0030057 desmosome", "go_biological_process": "GO:0031424 keratinization;GO:0042060 wound healing;GO:0045104 intermediate filament cytoskeleton organization;GO:0002786 regulation of antibacterial peptide production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0F0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0I4-1", "uniprot_id": [ { "id": "A0A9J7K0I4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0I4", "type": "external" } ], "mass": 92207.0, "length": 834, "protein_name": "Mannosyl-oligosaccharide glucosidase", "gene_name": "Mogs", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: mannosyl-oligosaccharide glucosidase isoform X2", "refseq_ac": [ { "id": "XP_027285197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285197", "type": "external" } ], "gene_names_uniprotkb": "Mogs", "gene_names_refseq": "Mogs", "protein_names_uniprotkb": "Mannosyl-oligosaccharide glucosidase; 3.2.1.106; Glucosidase I", "protein_names_refseq": "LOW QUALITY PROTEIN: mannosyl-oligosaccharide glucosidase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100689098)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor., [UniProtKB, UniProtKB]; In the context of N-glycan degradation, cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.106", "type": "external" } ], "go_molecular_function": "GO:0004573 Glc3Man9GlcNAc2 oligosaccharide glucosidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0009311 oligosaccharide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0I4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0I6-1", "uniprot_id": [ { "id": "A0A9J7K0I6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0I6", "type": "external" } ], "mass": 14276.0, "length": 139, "protein_name": "Large ribosomal subunit protein P1", "gene_name": "LOC100767529", "organism": "Hamster", "refseq_name": "60S acidic ribosomal protein P1-like", "refseq_ac": [ { "id": "XP_035294727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294727", "type": "external" } ], "gene_names_uniprotkb": "LOC100767529", "gene_names_refseq": "LOC100767529", "protein_names_uniprotkb": "Large ribosomal subunit protein P1; 60S acidic ribosomal protein P1", "protein_names_refseq": "60S acidic ribosomal protein P1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100767529)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in the elongation step of protein synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:0030295 protein kinase activator activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0I6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0J8-1", "uniprot_id": [ { "id": "A0A9J7K0J8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0J8", "type": "external" } ], "mass": 41797.0, "length": 381, "protein_name": "E3 ubiquitin-protein ligase KCMF1", "gene_name": "Kcmf1", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase KCMF1 isoform X2", "refseq_ac": [ { "id": "XP_027285262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285262", "type": "external" } ], "gene_names_uniprotkb": "Kcmf1", "gene_names_refseq": "Kcmf1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase KCMF1; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase KCMF1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753827)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0005764 lysosome;GO:0005770 late endosome", "go_biological_process": "GO:0099536 synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0J8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0U0-1", "uniprot_id": [ { "id": "A0A9J7K0U0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0U0", "type": "external" } ], "mass": 66318.0, "length": 612, "protein_name": "Nuclear receptor subfamily 1 group D member 1", "gene_name": "Nr1d1", "organism": "Hamster", "refseq_name": "nuclear receptor subfamily 1 group D member 1 isoform X2", "refseq_ac": [ { "id": "XP_035304043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304043", "type": "external" } ], "gene_names_uniprotkb": "Nr1d1", "gene_names_refseq": "Nr1d1", "protein_names_uniprotkb": "Nuclear receptor subfamily 1 group D member 1; Rev-erbA-alpha; V-erbA-related protein 1", "protein_names_refseq": "nuclear receptor subfamily 1 group D member 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100771327)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0043197 dendritic spine", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0U0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0X4-1", "uniprot_id": [ { "id": "A0A9J7K0X4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0X4", "type": "external" } ], "mass": 70604.0, "length": 616, "protein_name": "Secretogranin-2", "gene_name": "Scg2", "organism": "Hamster", "refseq_name": "secretogranin-2 isoform X1", "refseq_ac": [ { "id": "XP_035292821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292821", "type": "external" } ], "gene_names_uniprotkb": "Scg2", "gene_names_refseq": "Scg2", "protein_names_uniprotkb": "Secretogranin-2; Secretogranin II", "protein_names_refseq": "secretogranin-2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763908)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615515.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0001525 angiogenesis;GO:0048245 eosinophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0X4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K0X9-1", "uniprot_id": [ { "id": "A0A9J7K0X9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K0X9", "type": "external" } ], "mass": 23180.0, "length": 212, "protein_name": "Ras-related protein Rab-17", "gene_name": "Rab17", "organism": "Hamster", "refseq_name": "ras-related protein Rab-17 isoform X2", "refseq_ac": [ { "id": "XP_035295161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295161", "type": "external" } ], "gene_names_uniprotkb": "Rab17", "gene_names_refseq": "Rab17", "protein_names_uniprotkb": "Ras-related protein Rab-17; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-17 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768225)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0030425 dendrite;GO:0042470 melanosome;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0120031 plasma membrane bounded cell projection assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K0X9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K106-1", "uniprot_id": [ { "id": "A0A9J7K106_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K106", "type": "external" } ], "mass": 56285.0, "length": 491, "protein_name": "Cytochrome P450", "gene_name": "LOC113837198", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1-like", "refseq_ac": [ { "id": "XP_027286202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286202", "type": "external" } ], "gene_names_uniprotkb": "LOC113837198", "gene_names_refseq": "LOC113837198", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113837198)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K106-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K159-1", "uniprot_id": [ { "id": "A0A9J7K159_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K159", "type": "external" } ], "mass": 56663.0, "length": 494, "protein_name": "Cytochrome P450", "gene_name": "LOC100764865", "organism": "Hamster", "refseq_name": "cytochrome P450 2G1 isoform X2", "refseq_ac": [ { "id": "XP_027286422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286422", "type": "external" } ], "gene_names_uniprotkb": "LOC100764865", "gene_names_refseq": "LOC100764865", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2G1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764865)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K159-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1G4-1", "uniprot_id": [ { "id": "A0A9J7K1G4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1G4", "type": "external" } ], "mass": 103154.0, "length": 953, "protein_name": "Semaphorin-4F", "gene_name": "Sema4f", "organism": "Hamster", "refseq_name": "semaphorin-4F isoform X2", "refseq_ac": [ { "id": "XP_035304939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304939", "type": "external" } ], "gene_names_uniprotkb": "Sema4f", "gene_names_refseq": "Sema4f", "protein_names_uniprotkb": "Semaphorin-4F; Semaphorin-W", "protein_names_refseq": "semaphorin-4F isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759257)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 19% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable cell surface receptor that regulates oligodendroglial precursor cell migration. Might also regulate differentiation of oligodendroglial precursor cells. Has growth cone collapse activity against retinal ganglion-cell axons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0043204 perikaryon", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1G4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1J8-1", "uniprot_id": [ { "id": "A0A9J7K1J8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1J8", "type": "external" } ], "mass": 56942.0, "length": 499, "protein_name": "Serine/threonine-protein phosphatase", "gene_name": "LOC100761879", "organism": "Hamster", "refseq_name": "serine/threonine-protein phosphatase 5 isoform X2", "refseq_ac": [ { "id": "XP_027287125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287125", "type": "external" } ], "gene_names_uniprotkb": "LOC100761879", "gene_names_refseq": "LOC100761879", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase; 3.1.3.16", "protein_names_refseq": "serine/threonine-protein phosphatase 5 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100761879)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1J8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1M7-1", "uniprot_id": [ { "id": "A0A9J7K1M7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1M7", "type": "external" } ], "mass": 12780.0, "length": 123, "protein_name": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)", "gene_name": "LOC118238337", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase-like", "refseq_ac": [ { "id": "XP_035295988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295988", "type": "external" } ], "gene_names_uniprotkb": "LOC118238337", "gene_names_refseq": "LOC118238337", "protein_names_uniprotkb": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:118238337)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0006915 apoptotic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1M7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1P8-1", "uniprot_id": [ { "id": "A0A9J7K1P8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1P8", "type": "external" } ], "mass": 39477.0, "length": 356, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC100757678", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like isoform X2", "refseq_ac": [ { "id": "XP_027289620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289620", "type": "external" } ], "gene_names_uniprotkb": "LOC100757678", "gene_names_refseq": "LOC100757678", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757678)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027289620.1. COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K1P8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1R7-1", "uniprot_id": [ { "id": "A0A9J7K1R7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1R7", "type": "external" } ], "mass": 40306.0, "length": 368, "protein_name": "Proton-coupled zinc antiporter SLC30A8", "gene_name": "Slc30a8", "organism": "Hamster", "refseq_name": "zinc transporter 8", "refseq_ac": [ { "id": "XP_027287200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287200", "type": "external" } ], "gene_names_uniprotkb": "Slc30a8", "gene_names_refseq": "Slc30a8", "protein_names_uniprotkb": "Proton-coupled zinc antiporter SLC30A8; Solute carrier family 30 member 8; Zinc transporter 8", "protein_names_refseq": "zinc transporter 8", "tax_id": 10029, "disease": "", "pathway": " (cge:100775027)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0046872 metal ion binding;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030658 transport vesicle membrane", "go_biological_process": "GO:0010043 response to zinc ion;GO:0009749 response to glucose;GO:0030073 insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1R7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1X4-1", "uniprot_id": [ { "id": "A0A9J7K1X4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1X4", "type": "external" } ], "mass": 17229.0, "length": 156, "protein_name": "Nucleophosmin", "gene_name": "LOC107980155", "organism": "Hamster", "refseq_name": "nucleophosmin-like isoform X2", "refseq_ac": [ { "id": "XP_035296333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296333", "type": "external" } ], "gene_names_uniprotkb": "LOC107980155", "gene_names_refseq": "LOC107980155", "protein_names_uniprotkb": "Nucleophosmin", "protein_names_refseq": "nucleophosmin-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107980155)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0000055 ribosomal large subunit export from nucleus;GO:0006338 chromatin remodeling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K1X4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K1Z7-1", "uniprot_id": [ { "id": "A0A9J7K1Z7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K1Z7", "type": "external" } ], "mass": 69242.0, "length": 647, "protein_name": "Steryl-sulfatase", "gene_name": "LOC113838854", "organism": "Hamster", "refseq_name": "steryl-sulfatase-like", "refseq_ac": [ { "id": "XP_027290167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290167", "type": "external" } ], "gene_names_uniprotkb": "LOC113838854", "gene_names_refseq": "LOC113838854", "protein_names_uniprotkb": "Steryl-sulfatase; 3.1.6.2; Arylsulfatase C; Steroid sulfatase; Steryl-sulfate sulfohydrolase", "protein_names_refseq": "steryl-sulfatase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838854)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277415.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.6.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity;GO:0004773 steryl-sulfatase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007565 female pregnancy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K1Z7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K238-1", "uniprot_id": [ { "id": "A0A9J7K238_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K238", "type": "external" } ], "mass": 60037.0, "length": 543, "protein_name": "Terminal nucleotidyltransferase 4A", "gene_name": "Tent4a", "organism": "Hamster", "refseq_name": "terminal nucleotidyltransferase 4A isoform X1", "refseq_ac": [ { "id": "XP_007640534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640534", "type": "external" } ], "gene_names_uniprotkb": "Tent4a", "gene_names_refseq": "Tent4a", "protein_names_uniprotkb": "Terminal nucleotidyltransferase 4A; 2.7.7.19; DNA polymerase sigma; Non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal guanylyltransferase", "protein_names_refseq": "terminal nucleotidyltransferase 4A isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760867)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613856.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity;GO:0070568 guanylyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0031499 TRAMP complex", "go_biological_process": "GO:0031123 RNA 3'-end processing;GO:1905870 positive regulation of 3'-UTR-mediated mRNA stabilization;GO:0060212 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0043634 polyadenylation-dependent ncRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K238-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K265-1", "uniprot_id": [ { "id": "A0A9J7K265_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K265", "type": "external" } ], "mass": 34539.0, "length": 304, "protein_name": "DCN1-like protein", "gene_name": "LOC113837579", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: DCN1-like protein 3", "refseq_ac": [ { "id": "XP_035305828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305828", "type": "external" } ], "gene_names_uniprotkb": "LOC113837579", "gene_names_refseq": "LOC113837579", "protein_names_uniprotkb": "DCN1-like protein; Defective in cullin neddylation protein 1-like protein", "protein_names_refseq": "LOW QUALITY PROTEIN: DCN1-like protein 3", "tax_id": 10029, "disease": "", "pathway": " (cge:113837579)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage. At the cell membrane, can promote and as well inhibit cullins neddylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0032182 ubiquitin-like protein binding;GO:0097602 cullin family protein binding;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0045116 protein neddylation;GO:2000436 positive regulation of protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K265-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K288-1", "uniprot_id": [ { "id": "A0A9J7K288_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K288", "type": "external" } ], "mass": 41323.0, "length": 373, "protein_name": "Meiotic recombination protein DMC1/LIM15 homolog", "gene_name": "Dmc1", "organism": "Hamster", "refseq_name": "meiotic recombination protein DMC1/LIM15 homolog isoform X2", "refseq_ac": [ { "id": "XP_035294699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294699", "type": "external" } ], "gene_names_uniprotkb": "Dmc1", "gene_names_refseq": "Dmc1", "protein_names_uniprotkb": "Meiotic recombination protein DMC1/LIM15 homolog", "protein_names_refseq": "meiotic recombination protein DMC1/LIM15 homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100750348)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 13% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0000150 DNA strand exchange activity;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome", "go_biological_process": "GO:0006312 mitotic recombination;GO:0007283 spermatogenesis;GO:0007131 reciprocal meiotic recombination;GO:0007292 female gamete generation;GO:0000730 DNA recombinase assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K288-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K296-1", "uniprot_id": [ { "id": "A0A9J7K296_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K296", "type": "external" } ], "mass": 50183.0, "length": 478, "protein_name": "Thymidine phosphorylase", "gene_name": "Tymp", "organism": "Hamster", "refseq_name": "thymidine phosphorylase", "refseq_ac": [ { "id": "XP_035296716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296716", "type": "external" } ], "gene_names_uniprotkb": "Tymp", "gene_names_refseq": "Tymp", "protein_names_uniprotkb": "Thymidine phosphorylase; 2.4.2.4; TP; TdRPase", "protein_names_refseq": "thymidine phosphorylase", "tax_id": 10029, "disease": "", "pathway": " (cge:100757152)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.4", "type": "external" } ], "go_molecular_function": "GO:0004645 1,4-alpha-oligoglucan phosphorylase activity;GO:0009032 thymidine phosphorylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006213 pyrimidine nucleoside metabolic process;GO:0006206 pyrimidine nucleobase metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K296-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K298-1", "uniprot_id": [ { "id": "A0A9J7K298_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K298", "type": "external" } ], "mass": 93848.0, "length": 816, "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plcd4", "organism": "Hamster", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "refseq_ac": [ { "id": "XP_035294733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294733", "type": "external" } ], "gene_names_uniprotkb": "Plcd4", "gene_names_refseq": "Plcd4", "protein_names_uniprotkb": "Phosphoinositide phospholipase C; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "tax_id": 10029, "disease": "", "pathway": " (cge:100751872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" } ], "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K298-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2A6-1", "uniprot_id": [ { "id": "A0A9J7K2A6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2A6", "type": "external" } ], "mass": 90664.0, "length": 816, "protein_name": "Chloride channel protein", "gene_name": "Clcn5", "organism": "Hamster", "refseq_name": "H(+)/Cl(-) exchange transporter 5", "refseq_ac": [ { "id": "XP_027289084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289084", "type": "external" } ], "gene_names_uniprotkb": "Clcn5", "gene_names_refseq": "Clcn5", "protein_names_uniprotkb": "Chloride channel protein", "protein_names_refseq": "H(+)/Cl(-) exchange transporter 5", "tax_id": 10029, "disease": "", "pathway": " (cge:100754025)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0015297 antiporter activity;GO:0005247 voltage-gated chloride channel activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0008021 synaptic vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2A6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2E0-1", "uniprot_id": [ { "id": "A0A9J7K2E0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2E0", "type": "external" } ], "mass": 20380.0, "length": 185, "protein_name": "Nucleophosmin", "gene_name": "LOC100771119", "organism": "Hamster", "refseq_name": "nucleophosmin-like", "refseq_ac": [ { "id": "XP_035294858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294858", "type": "external" } ], "gene_names_uniprotkb": "LOC100771119", "gene_names_refseq": "LOC100771119", "protein_names_uniprotkb": "Nucleophosmin", "protein_names_refseq": "nucleophosmin-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100771119)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0000055 ribosomal large subunit export from nucleus;GO:0006338 chromatin remodeling;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2E0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2P9-1", "uniprot_id": [ { "id": "A0A9J7K2P9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2P9", "type": "external" } ], "mass": 44239.0, "length": 391, "protein_name": "Lysosomal Pro-X carboxypeptidase", "gene_name": "LOC100753648", "organism": "Hamster", "refseq_name": "lysosomal Pro-X carboxypeptidase-like", "refseq_ac": [ { "id": "XP_035297246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297246", "type": "external" } ], "gene_names_uniprotkb": "LOC100753648", "gene_names_refseq": "LOC100753648", "protein_names_uniprotkb": "Lysosomal Pro-X carboxypeptidase; 3.4.16.2; Proline carboxypeptidase; Prolylcarboxypeptidase", "protein_names_refseq": "lysosomal Pro-X carboxypeptidase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100753648)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0004185 serine-type carboxypeptidase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "GO:0006508 proteolysis;GO:0043535 regulation of blood vessel endothelial cell migration;GO:0003085 negative regulation of systemic arterial blood pressure;GO:0060055 angiogenesis involved in wound healing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2P9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2Q4-1", "uniprot_id": [ { "id": "A0A9J7K2Q4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2Q4", "type": "external" } ], "mass": 110065.0, "length": 975, "protein_name": "Aminopeptidase", "gene_name": "Anpep", "organism": "Hamster", "refseq_name": "aminopeptidase N isoform X2", "refseq_ac": [ { "id": "XP_035297261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297261", "type": "external" } ], "gene_names_uniprotkb": "Anpep", "gene_names_refseq": "Anpep", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "aminopeptidase N isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751632)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042277 peptide binding;GO:0070006 metalloaminopeptidase activity;GO:0016285 alanyl aminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0016485 protein processing;GO:0030154 cell differentiation;GO:0043171 peptide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2Q4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2Q6-1", "uniprot_id": [ { "id": "A0A9J7K2Q6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2Q6", "type": "external" } ], "mass": 141599.0, "length": 1264, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgkk", "organism": "Hamster", "refseq_name": "diacylglycerol kinase kappa isoform X2", "refseq_ac": [ { "id": "XP_027288919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288919", "type": "external" } ], "gene_names_uniprotkb": "Dgkk", "gene_names_refseq": "Dgkk", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase kappa isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100755575)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.107", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.107", "type": "external" }, { "id": "2.7.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.94", "type": "external" }, { "id": "2.7.1.138", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138", "type": "external" } ], "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0046486 glycerolipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2Q6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2X0-1", "uniprot_id": [ { "id": "A0A9J7K2X0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2X0", "type": "external" } ], "mass": 411736.0, "length": 3613, "protein_name": "Sucrase-isomaltase, intestinal", "gene_name": "Mgam", "organism": "Hamster", "refseq_name": "maltase-glucoamylase, intestinal isoform X2", "refseq_ac": [ { "id": "XP_035306801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306801", "type": "external" } ], "gene_names_uniprotkb": "Mgam", "gene_names_refseq": "Mgam", "protein_names_uniprotkb": "Sucrase-isomaltase, intestinal", "protein_names_refseq": "maltase-glucoamylase, intestinal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769016)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0030246 carbohydrate binding;GO:0004574 oligo-1,6-glucosidase activity;GO:0004575 sucrose alpha-glucosidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0045177 apical part of cell;GO:0012505 endomembrane system", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2X0-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K2Y4-1", "uniprot_id": [ { "id": "A0A9J7K2Y4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K2Y4", "type": "external" } ], "mass": 214605.0, "length": 1914, "protein_name": "Voltage-dependent L-type calcium channel subunit alpha", "gene_name": "Cacna1f", "organism": "Hamster", "refseq_name": "voltage-dependent L-type calcium channel subunit alpha-1F isoform X2", "refseq_ac": [ { "id": "XP_027288984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288984", "type": "external" } ], "gene_names_uniprotkb": "Cacna1f", "gene_names_refseq": "Cacna1f", "protein_names_uniprotkb": "Voltage-dependent L-type calcium channel subunit alpha", "protein_names_refseq": "voltage-dependent L-type calcium channel subunit alpha-1F isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757994)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008331 high voltage-gated calcium channel activity", "go_cellular_component": "GO:0005891 voltage-gated calcium channel complex", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0007601 visual perception;GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K2Y4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K338-1", "uniprot_id": [ { "id": "A0A9J7K338_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K338", "type": "external" } ], "mass": 92172.0, "length": 839, "protein_name": "Semaphorin-4G", "gene_name": "Sema4g", "organism": "Hamster", "refseq_name": "semaphorin-4G isoform X2", "refseq_ac": [ { "id": "XP_035297700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297700", "type": "external" } ], "gene_names_uniprotkb": "Sema4g", "gene_names_refseq": "Sema4g", "protein_names_uniprotkb": "Semaphorin-4G", "protein_names_refseq": "semaphorin-4G isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756606)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cell surface receptor for PLXNB2. May play a role in axon guidance., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K338-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3R5-1", "uniprot_id": [ { "id": "A0A9J7K3R5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3R5", "type": "external" } ], "mass": 145338.0, "length": 1293, "protein_name": "Receptor protein-tyrosine kinase", "gene_name": "LOC100760475", "organism": "Hamster", "refseq_name": "receptor tyrosine-protein kinase erbB-4 isoform X2", "refseq_ac": [ { "id": "XP_035294730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294730", "type": "external" } ], "gene_names_uniprotkb": "LOC100760475", "gene_names_refseq": "LOC100760475", "protein_names_uniprotkb": "Receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "receptor tyrosine-protein kinase erbB-4 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760475)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0038131 neuregulin receptor activity;GO:0005524 ATP binding;GO:0005154 epidermal growth factor receptor binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0043235 receptor complex;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3R5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7TQ49-1", "uniprot_id": [ { "id": "GLCNE_CRIGR", "url": "https://www.uniprot.org/uniprot/Q7TQ49", "type": "external" } ], "mass": 79241.0, "length": 722, "protein_name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "gene_name": "GNE", "organism": "Hamster", "refseq_name": "bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "refseq_ac": [ { "id": "NP_001233638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233638", "type": "external" } ], "gene_names_uniprotkb": "GNE; GLCNE", "gene_names_refseq": "GLCNE; Gne; Uae1", "protein_names_uniprotkb": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; ManAc kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimerase", "protein_names_refseq": "UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine-2-epimerase/N- acetylmannosamine kinase; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "tax_id": 10029, "disease": "", "pathway": " (cge:100689450)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14561743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AB107226.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04275174, SAMN04275175 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB107226.1., [RefSeq]; Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids (PubMed:14561743). By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation, playing a role in embryonic angiogenesis. Sialic acids represent a category of negatively charged sugars that reside on the surface of cells as terminal components of glycoconjugates and mediate important functions in various cellular processes, including cell adhesion, signal transduction, and cellular recognition (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.60", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.60", "type": "external" }, { "id": "3.2.1.183", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.183", "type": "external" } ], "go_molecular_function": "GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity;GO:0009384 N-acylmannosamine kinase activity;GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006045 N-acetylglucosamine biosynthetic process;GO:0046380 N-acetylneuraminate biosynthetic process;GO:0006047 UDP-N-acetylglucosamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7TQ49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8R4A8-1", "uniprot_id": [ { "id": "GNAS_CRIGR", "url": "https://www.uniprot.org/uniprot/Q8R4A8", "type": "external" } ], "mass": 45650.0, "length": 394, "protein_name": "Guanine nucleotide-binding protein G(s) subunit alpha", "gene_name": "GNAS", "organism": "Hamster", "refseq_name": "guanine nucleotide-binding protein G(s) subunit alpha", "refseq_ac": [ { "id": "NP_001230982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230982", "type": "external" } ], "gene_names_uniprotkb": "GNAS", "gene_names_refseq": "Gnas", "protein_names_uniprotkb": "Guanine nucleotide-binding protein G(s) subunit alpha; Adenylate cyclase-stimulating G alpha protein", "protein_names_refseq": "Adenylate cyclase-stimulating G alpha protein; GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus; guanine nucleotide-binding protein G(s) alpha subunit; guanine nucleotide-binding protein G(s) subunit alpha", "tax_id": 10029, "disease": "", "pathway": " (cge:100689067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF487552.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN09948071, SAMN09948077 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF487552.1. On Nov 17, 2012 this sequence version replaced XP_003496797.1., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3HR11", "ec_number_list": [], "go_molecular_function": "GO:0031698 beta-2 adrenergic receptor binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0005159 insulin-like growth factor receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8R4A8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9R152-1", "uniprot_id": [ { "id": "PARP1_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9R152", "type": "external" } ], "mass": 112532.0, "length": 1013, "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "organism": "Hamster", "refseq_name": "poly [ADP-ribose] polymerase 1", "refseq_ac": [ { "id": "NP_001233650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001233650", "type": "external" } ], "gene_names_uniprotkb": "PARP1; ADPRT", "gene_names_refseq": "ADPRT; ARTD1; PARP-1; Parp1; Parp", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase 1; 2.4.2.-; 2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 1; ADPRT 1; ARTD1; DNA ADP-ribosyltransferase PARP1; NAD(+) ADP-ribosyltransferase 1; PARP-1; Poly [ADP-ribose] polymerase 1, 24-kDa form; Poly [ADP-ribose] polymerase 1, 89-kDa form; Poly[ADP-ribose] synthase 1; Protein poly-ADP-ribosyltransferase PARP1", "protein_names_refseq": "ADP-ribosyltransferase diphtheria toxin-like 1; ADPRT 1; DNA ADP-ribosyltransferase PARP1; NAD(+) ADP-ribosyltransferase 1; Poly[ADP-ribose] synthase 1; poly ADP-ribose polymerase; poly [ADP-ribose] polymerase 1; protein poly-ADP-ribosyltransferase PARP1", "tax_id": 10029, "disease": "", "pathway": " (cge:100689463)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11382339;24210699;37300987", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF168781.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04275174, SAMN04275175 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF168781.1., [RefSeq]; Findings show that PARP-End-Joining(EJ)is solely used when Ku is deficient but not when either DNA-PKcs or Xrcc4 is lacking; PARP-EJ may work on double strand breaks ends at high fidelity manner, as evident from the unchanged efficiency upon blocking end resection, [RefSeq, PubMed]; PARP deficiency causes hypersensitivity to Taxol through oxidative stress induced DNA damage., [RefSeq, PubMed]; Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (By similarity). Mediates glutamate, aspartate, serine, histidine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage (By similarity). Specificity for the different amino acids is conferred by interacting factors, such as HPF1 and NMNAT1 (By similarity). Following interaction with HPF1, catalyzes serine ADP-ribosylation of target proteins; HPF1 confers serine specificity by completing the PARP1 active site. Also catalyzes tyrosine ADP-ribosylation of target proteins following interaction with HPF1 (By similarity). Following interaction with NMNAT1, catalyzes glutamate and aspartate ADP-ribosylation of target proteins; NMNAT1 confers glutamate and aspartate specificity (By similarity). PARP1 initiates the repair of DNA breaks: recognizes and binds DNA breaks within chromatin and recruits HPF1, licensing serine ADP-ribosylation of target proteins, such as histones (H2BS6ADPr and H3S10ADPr), thereby promoting decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand breaks. HPF1 initiates serine ADP-ribosylation but restricts the polymerase activity of PARP1 in order to limit the length of poly-ADP-ribose chains. In addition to base excision repair (BER) pathway, also involved in double-strand breaks (DSBs) repair: together with TIMELESS, accumulates at DNA damage sites and promotes homologous recombination repair by mediating poly-ADP-ribosylation. Mediates the poly-ADP-ribosylation of a number of proteins, including itself, APLF, CHFR and NFAT5. In addition to proteins, also able to ADP-ribosylate DNA: catalyzes ADP-ribosylation of DNA strand break termini containing terminal phosphates and a 2'-OH group in single- and double-stranded DNA, respectively. Required for PARP9 and DTX3L recruitment to DNA damage sites. PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites (By similarity). PARP1-mediated DNA repair in neurons plays a role in sleep: senses DNA damage in neurons and promotes sleep, facilitating efficient DNA repair. In addition to DNA repair, also involved in other processes, such as transcription regulation, programmed cell death, membrane repair, adipogenesis and innate immunity (By similarity). Acts as a repressor of transcription: binds to nucleosomes and modulates chromatin structure in a manner similar to histone H1, thereby altering RNA polymerase II. Acts both as a positive and negative regulator of transcription elongation, depending on the context. Acts as a positive regulator of transcription elongation by mediating poly-ADP-ribosylation of NELFE, preventing RNA-binding activity of NELFE and relieving transcription pausing. Acts as a negative regulator of transcription elongation in response to DNA damage by catalyzing poly-ADP-ribosylation of CCNT1, disrupting the phase separation activity of CCNT1 and subsequent activation of CDK9. Involved in replication fork progression following interaction with CARM1: mediates poly-ADP-ribosylation at replication forks, slowing fork progression (By similarity). Poly-ADP-ribose chains generated by PARP1 also play a role in poly-ADP-ribose-dependent cell death, a process named parthanatos. Also acts as a negative regulator of the cGAS-STING pathway. Acts by mediating poly-ADP-ribosylation of CGAS: PARP1 translocates into the cytosol following phosphorylation by PRKDC and catalyzes poly-ADP-ribosylation and inactivation of CGAS. Acts as a negative regulator of adipogenesis: catalyzes poly-ADP-ribosylation of histone H2B on 'Glu-35' (H2BE35ADPr) following interaction with NMNAT1, inhibiting phosphorylation of H2B at 'Ser-36' (H2BS36ph), thereby blocking expression of pro-adipogenetic genes (By similarity). Involved in the synthesis of ATP in the nucleus, together with NMNAT1, PARG and NUDT5. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (By similarity). Plays a role in sister chromatid cohesion by mediating ADP-ribosylation of RSMC during S phase which promotes the interaction between RSMC and CDCA5/sororin, leading to enhanced interaction of CDCA5/sororin with the cohesin complex and promotion of sister chromatid cohesion (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Promotes AIFM1-mediated apoptosis. This form, which translocates into the cytoplasm following cleavage by caspase-3 (CASP3) and caspase-7 (CASP7) in response to apoptosis, is auto-poly-ADP-ribosylated and serves as a poly-ADP-ribose carrier to induce AIFM1-mediated apoptosis., [UniProtKB, UniProtKB]; This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.4.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.30", "type": "external" } ], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0003684 damaged DNA binding;GO:0051287 NAD binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000785 chromatin", "go_biological_process": "GO:0070213 protein auto-ADP-ribosylation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9R152-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9R1F8-1", "uniprot_id": [ { "id": "TLR2_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9R1F8", "type": "external" } ], "mass": 89210.0, "length": 784, "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "organism": "Hamster", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TLR2", "gene_names_refseq": "", "protein_names_uniprotkb": "Toll-like receptor 2", "protein_names_refseq": "", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "10358136", "class_list": "", "function": "Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042497 triacyl lipopeptide binding;GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0001819 positive regulation of cytokine production;GO:0002224 toll-like receptor signaling pathway;GO:0032680 regulation of tumor necrosis factor production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9R1F8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Z302-1", "uniprot_id": [ { "id": "OXDA_CRIGR", "url": "https://www.uniprot.org/uniprot/Q9Z302", "type": "external" } ], "mass": 39146.0, "length": 346, "protein_name": "D-amino-acid oxidase", "gene_name": "DAO", "organism": "Hamster", "refseq_name": "D-amino-acid oxidase", "refseq_ac": [ { "id": "NP_001231338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231338", "type": "external" } ], "gene_names_uniprotkb": "DAO", "gene_names_refseq": "DAAO; DAMOX; Dao", "protein_names_uniprotkb": "D-amino-acid oxidase; 1.4.3.3; DAAO; DAMOX; DAO", "protein_names_refseq": "D-amino-acid oxidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100689280)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN09948084, SAMN09948097 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AFTD01119782.1 and AFTD01119781.1. On or before Mar 28, 2018 this sequence version replaced XP_007642325.1, NP_001231338.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalyzes the oxidative deamination of D-amino acids with broad substrate specificity. Required to catabolize D-amino acids synthesized endogenously, of gastrointestinal bacterial origin or obtained from the diet, and to use these as nutrients. Regulates the level of D-amino acid neurotransmitters in the brain, such as D-serine, a co-agonist of N-methyl D-aspartate (NMDA) receptors, and may modulate synaptic transmission. Catalyzes the first step of the racemization of D-DOPA to L-DOPA, for possible use in an alternative dopamine biosynthesis pathway. Also catalyzes the first step of the chiral inversion of N(gamma)-nitro-D-arginine methyl ester (D-NNA) to its L-enantiomer L-NNA that acts as a nitric oxide synthase inhibitor. The hydrogen peroxide produced in the reaction provides protection against microbial infection; it contributes to the oxidative killing activity of phagocytic leukocytes and protects against bacterial colonization of the small intestine. Enzyme secreted into the lumen of the intestine may not be catalytically active and could instead be proteolytically cleaved into peptides with antimicrobial activity (By similarity). The hydrogen peroxide produced in the reaction may also play a role in promoting cellular senescence in response to DNA damage (By similarity). Could act as a detoxifying agent which removes D-amino acids accumulated during aging (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.1", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0003884 D-amino-acid oxidase activity;GO:0043799 glycine oxidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005829 cytosol;GO:0048786 presynaptic active zone", "go_biological_process": "GO:0070945 neutrophil-mediated killing of gram-negative bacterium;GO:0036088 D-serine catabolic process;GO:0055130 D-alanine catabolic process;GO:0042416 dopamine biosynthetic process;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9Z302-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBK3-1", "uniprot_id": [ { "id": "A0A9J7KBK3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBK3", "type": "external" } ], "mass": 75059.0, "length": 673, "protein_name": "E3 ubiquitin-protein ligase TRAF7", "gene_name": "Traf7", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase TRAF7 isoform X1", "refseq_ac": [ { "id": "XP_035303570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303570", "type": "external" } ], "gene_names_uniprotkb": "Traf7", "gene_names_refseq": "Traf7", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRAF7; 2.3.2.27; RING-type E3 ubiquitin transferase TRAF7; TNF receptor-associated factor 7", "protein_names_refseq": "E3 ubiquitin-protein ligase TRAF7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756531)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0051247 positive regulation of protein metabolic process;GO:0006915 apoptotic process;GO:0000027 ribosomal large subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3T5-1", "uniprot_id": [ { "id": "A0A9J7K3T5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3T5", "type": "external" } ], "mass": 93934.0, "length": 860, "protein_name": "RNA helicase", "gene_name": "Ddx4", "organism": "Hamster", "refseq_name": "probable ATP-dependent RNA helicase DDX4 isoform X1", "refseq_ac": [ { "id": "XP_035296461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296461", "type": "external" } ], "gene_names_uniprotkb": "Ddx4", "gene_names_refseq": "Ddx4", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13; DEAD box protein 4; Vasa homolog", "protein_names_refseq": "probable ATP-dependent RNA helicase DDX4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle. Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0033391 chromatoid body;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3T5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KE81-1", "uniprot_id": [ { "id": "A0A9J7KE81_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KE81", "type": "external" } ], "mass": 90883.0, "length": 807, "protein_name": "Serine/threonine-protein kinase Nek4", "gene_name": "Nek4", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase Nek4 isoform X1", "refseq_ac": [ { "id": "XP_035306243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306243", "type": "external" } ], "gene_names_uniprotkb": "Nek4", "gene_names_refseq": "Nek4", "protein_names_uniprotkb": "Serine/threonine-protein kinase Nek4; 2.7.11.1; Never in mitosis A-related kinase 4; Serine/threonine-protein kinase 2", "protein_names_refseq": "serine/threonine-protein kinase Nek4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100761888)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 130 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) and transcript sequence (IACG01057238.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005929 cilium;GO:0005737 cytoplasm", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0006974 DNA damage response;GO:0045893 positive regulation of DNA-templated transcription;GO:2000772 regulation of cellular senescence", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KE81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KCT1-1", "uniprot_id": [ { "id": "A0A9J7KCT1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KCT1", "type": "external" } ], "mass": 81870.0, "length": 753, "protein_name": "CCR4-NOT transcription complex subunit 3", "gene_name": "Cnot3", "organism": "Hamster", "refseq_name": "CCR4-NOT transcription complex subunit 3 isoform X2", "refseq_ac": [ { "id": "XP_027286797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286797", "type": "external" } ], "gene_names_uniprotkb": "Cnot3", "gene_names_refseq": "Cnot3", "protein_names_uniprotkb": "CCR4-NOT transcription complex subunit 3; CCR4-associated factor 3", "protein_names_refseq": "CCR4-NOT transcription complex subunit 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100765854)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000932 P-body;GO:0030015 CCR4-NOT core complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006417 regulation of translation;GO:0006355 regulation of DNA-templated transcription;GO:0001829 trophectodermal cell differentiation;GO:0007368 determination of left/right symmetry", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KCT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9A2-1", "uniprot_id": [ { "id": "A0A9J7K9A2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9A2", "type": "external" } ], "mass": 96248.0, "length": 851, "protein_name": "Phospholipase A2", "gene_name": "Pla2g4f", "organism": "Hamster", "refseq_name": "cytosolic phospholipase A2 zeta isoform X1", "refseq_ac": [ { "id": "XP_035300455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300455", "type": "external" } ], "gene_names_uniprotkb": "Pla2g4f", "gene_names_refseq": "Pla2g4f", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "cytosolic phospholipase A2 zeta isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100770605)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "1.11.1.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.27", "type": "external" }, { "id": "3.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.32", "type": "external" }, { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "3.1.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.3", "type": "external" }, { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0031982 vesicle;GO:0032587 ruffle membrane", "go_biological_process": "GO:0046475 glycerophospholipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9A2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBU9-1", "uniprot_id": [ { "id": "A0A9J7KBU9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBU9", "type": "external" } ], "mass": 71896.0, "length": 622, "protein_name": "Tyrosine-protein kinase", "gene_name": "Itk", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase ITK/TSK isoform X2", "refseq_ac": [ { "id": "XP_035303863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303863", "type": "external" } ], "gene_names_uniprotkb": "Itk", "gene_names_refseq": "Itk", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase ITK/TSK isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100770087)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0042110 T cell activation;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KCA8-1", "uniprot_id": [ { "id": "A0A9J7KCA8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KCA8", "type": "external" } ], "mass": 135856.0, "length": 1250, "protein_name": "Protein transport protein Sec31A", "gene_name": "Sec31a", "organism": "Hamster", "refseq_name": "protein transport protein Sec31A isoform X2", "refseq_ac": [ { "id": "XP_027243432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243432", "type": "external" } ], "gene_names_uniprotkb": "Sec31a", "gene_names_refseq": "Sec31a", "protein_names_uniprotkb": "Protein transport protein Sec31A; SEC31-like protein 1; SEC31-related protein A", "protein_names_refseq": "protein transport protein Sec31A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762780)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0048306 calcium-dependent protein binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0015031 protein transport;GO:0007029 endoplasmic reticulum organization;GO:0051592 response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KCA8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4C7-1", "uniprot_id": [ { "id": "A0A9J7K4C7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4C7", "type": "external" } ], "mass": 45935.0, "length": 410, "protein_name": "Dematin", "gene_name": "Dmtn", "organism": "Hamster", "refseq_name": "dematin isoform X1", "refseq_ac": [ { "id": "XP_035308824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308824", "type": "external" } ], "gene_names_uniprotkb": "Dmtn", "gene_names_refseq": "Dmtn", "protein_names_uniprotkb": "Dematin; Dematin actin-binding protein; Erythrocyte membrane protein band 4.9", "protein_names_refseq": "dematin isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100764907)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0005102 signaling receptor binding;GO:0030507 spectrin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0048471 perinuclear region of cytoplasm;GO:0042995 cell projection", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0030032 lamellipodium assembly;GO:0008360 regulation of cell shape;GO:0051693 actin filament capping;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4C7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KDW4-1", "uniprot_id": [ { "id": "A0A9J7KDW4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KDW4", "type": "external" } ], "mass": 130005.0, "length": 1184, "protein_name": "Integrin alpha-7", "gene_name": "Itga7", "organism": "Hamster", "refseq_name": "integrin alpha-7 isoform X3", "refseq_ac": [ { "id": "XP_035306529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306529", "type": "external" } ], "gene_names_uniprotkb": "Itga7", "gene_names_refseq": "Itga7", "protein_names_uniprotkb": "Integrin alpha-7", "protein_names_refseq": "integrin alpha-7 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773038)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion;GO:0050900 leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KDW4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8C2LN53-1", "uniprot_id": [ { "id": "A0A8C2LN53_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A8C2LN53", "type": "external" } ], "mass": 79063.0, "length": 717, "protein_name": "DNA-binding protein RFX2", "gene_name": "Rfx2", "organism": "Hamster", "refseq_name": "DNA-binding protein RFX2 isoform X1", "refseq_ac": [ { "id": "XP_003501810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501810", "type": "external" } ], "gene_names_uniprotkb": "Rfx2", "gene_names_refseq": "Rfx2", "protein_names_uniprotkb": "DNA-binding protein RFX2; Regulatory factor X 2", "protein_names_refseq": "DNA-binding protein RFX2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100760779)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613861.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0030030 cell projection organization;GO:0060271 cilium assembly;GO:0001675 acrosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A8C2LN53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KC61-1", "uniprot_id": [ { "id": "A0A9J7KC61_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KC61", "type": "external" } ], "mass": 55479.0, "length": 485, "protein_name": "tRNA-splicing endonuclease subunit Sen2", "gene_name": "Tsen2", "organism": "Hamster", "refseq_name": "tRNA-splicing endonuclease subunit Sen2 isoform X1", "refseq_ac": [ { "id": "XP_035304261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304261", "type": "external" } ], "gene_names_uniprotkb": "Tsen2", "gene_names_refseq": "Tsen2", "protein_names_uniprotkb": "tRNA-splicing endonuclease subunit Sen2; 4.6.1.16", "protein_names_refseq": "tRNA-splicing endonuclease subunit Sen2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768441)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Probably carries the active site for 5'-splice site cleavage. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0000213 tRNA-intron lyase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000214 tRNA-intron endonuclease complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0000379 tRNA-type intron splice site recognition and cleavage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KC61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K897-1", "uniprot_id": [ { "id": "A0A9J7K897_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K897", "type": "external" } ], "mass": 29907.0, "length": 264, "protein_name": "Nicotinamide-nucleotide adenylyltransferase", "gene_name": "Nmnat3", "organism": "Hamster", "refseq_name": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform X1", "refseq_ac": [ { "id": "XP_035299771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299771", "type": "external" } ], "gene_names_uniprotkb": "Nmnat3", "gene_names_refseq": "Nmnat3", "protein_names_uniprotkb": "Nicotinamide-nucleotide adenylyltransferase; 2.7.7.18; 2.7.7.1", "protein_names_refseq": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:103160971)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury. May be involved in the maintenance of axonal integrity. Also functions as a stress-response chaperone protein that prevents toxic aggregation of proteins; this function may be independent of its NAD(+) synthesis activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.1", "type": "external" }, { "id": "2.7.7.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.18", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004515 nicotinate-nucleotide adenylyltransferase activity;GO:0000309 nicotinamide-nucleotide adenylyltransferase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005739 mitochondrion", "go_biological_process": "GO:0034355 NAD+ biosynthetic process via the salvage pathway;GO:0009435 NAD+ biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K897-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAS7-1", "uniprot_id": [ { "id": "A0A9J7KAS7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAS7", "type": "external" } ], "mass": 12169.0, "length": 105, "protein_name": "Protein S100-A10", "gene_name": "S100a10", "organism": "Hamster", "refseq_name": "protein S100-A10 isoform X1", "refseq_ac": [ { "id": "XP_035306952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306952", "type": "external" } ], "gene_names_uniprotkb": "S100a10", "gene_names_refseq": "S100a10", "protein_names_uniprotkb": "Protein S100-A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11", "protein_names_refseq": "protein S100-A10 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100759158)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0048306 calcium-dependent protein binding;GO:0044325 transmembrane transporter binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft", "go_biological_process": "GO:0010756 positive regulation of plasminogen activation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0072659 protein localization to plasma membrane;GO:0051496 positive regulation of stress fiber assembly;GO:0051894 positive regulation of focal adhesion assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBK7-1", "uniprot_id": [ { "id": "A0A9J7KBK7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBK7", "type": "external" } ], "mass": 29281.0, "length": 264, "protein_name": "Enolase-phosphatase E1", "gene_name": "Enoph1", "organism": "Hamster", "refseq_name": "enolase-phosphatase E1 isoform X1", "refseq_ac": [ { "id": "XP_035307985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307985", "type": "external" } ], "gene_names_uniprotkb": "Enoph1; ENOPH1; MASA", "gene_names_refseq": "Enoph1", "protein_names_uniprotkb": "Enolase-phosphatase E1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; 3.1.3.77; MASA homolog", "protein_names_refseq": "enolase-phosphatase E1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767312)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.77", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0043874 acireductone synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBK7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K813-1", "uniprot_id": [ { "id": "A0A9J7K813_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K813", "type": "external" } ], "mass": 50595.0, "length": 451, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "Smad3", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 3 isoform X2", "refseq_ac": [ { "id": "XP_035299647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299647", "type": "external" } ], "gene_names_uniprotkb": "Smad3", "gene_names_refseq": "Smad3", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759220)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0031962 nuclear mineralocorticoid receptor binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006955 immune response;GO:0010628 positive regulation of gene expression;GO:0045429 positive regulation of nitric oxide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K813-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAM8-1", "uniprot_id": [ { "id": "A0A9J7KAM8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAM8", "type": "external" } ], "mass": 51337.0, "length": 465, "protein_name": "Paired box protein Pax-6", "gene_name": "Pax6", "organism": "Hamster", "refseq_name": "paired box protein Pax-6 isoform X1", "refseq_ac": [ { "id": "XP_035297545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297545", "type": "external" } ], "gene_names_uniprotkb": "Pax6", "gene_names_refseq": "Pax6", "protein_names_uniprotkb": "Paired box protein Pax-6; Oculorhombin", "protein_names_refseq": "paired box protein Pax-6 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613653.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Acts as a transcriptional repressor of NFATC1-mediated gene expression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0003723 RNA binding;GO:0019901 protein kinase binding;GO:0031625 ubiquitin protein ligase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0003322 pancreatic A cell development;GO:0048708 astrocyte differentiation;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KCS6-1", "uniprot_id": [ { "id": "A0A9J7KCS6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KCS6", "type": "external" } ], "mass": 71956.0, "length": 637, "protein_name": "Complement factor I", "gene_name": "Cfi", "organism": "Hamster", "refseq_name": "complement factor I isoform X2", "refseq_ac": [ { "id": "XP_035306663", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306663", "type": "external" } ], "gene_names_uniprotkb": "Cfi", "gene_names_refseq": "Cfi", "protein_names_uniprotkb": "Complement factor I; 3.4.21.45; C3B/C4B inactivator", "protein_names_refseq": "complement factor I isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767614)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Trypsin-like serine protease that plays an essential role in regulating the immune response by controlling all complement pathways. Inhibits these pathways by cleaving three peptide bonds in the alpha-chain of C3b and two bonds in the alpha-chain of C4b thereby inactivating these proteins. Essential cofactors for these reactions include factor H and C4BP in the fluid phase and membrane cofactor protein/CD46 and CR1 on cell surfaces. The presence of these cofactors on healthy cells allows degradation of deposited C3b by CFI in order to prevent undesired complement activation, while in apoptotic cells or microbes, the absence of such cofactors leads to C3b-mediated complement activation and subsequent opsonization., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KCS6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K738-1", "uniprot_id": [ { "id": "A0A9J7K738_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K738", "type": "external" } ], "mass": 43009.0, "length": 394, "protein_name": "IST1 homolog", "gene_name": "Ist1", "organism": "Hamster", "refseq_name": "IST1 homolog isoform X2", "refseq_ac": [ { "id": "XP_035298558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298558", "type": "external" } ], "gene_names_uniprotkb": "Ist1", "gene_names_refseq": "Ist1", "protein_names_uniprotkb": "IST1 homolog; Charged multivesicular body protein 8", "protein_names_refseq": "IST1 homolog isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756334)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation. Is required for efficient abscission during cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2. Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0090541 MIT domain binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005813 centrosome;GO:0031410 cytoplasmic vesicle;GO:0030496 midbody;GO:0005829 cytosol", "go_biological_process": "GO:0015031 protein transport;GO:0051301 cell division;GO:0045862 positive regulation of proteolysis;GO:0061952 midbody abscission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K738-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3V7-1", "uniprot_id": [ { "id": "A0A9J7K3V7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3V7", "type": "external" } ], "mass": 273255.0, "length": 2463, "protein_name": "Polycystin-1-like protein 2", "gene_name": "Pkd1l2", "organism": "Hamster", "refseq_name": "polycystic kidney disease protein 1-like 2 isoform X2", "refseq_ac": [ { "id": "XP_035298594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298594", "type": "external" } ], "gene_names_uniprotkb": "Pkd1l2", "gene_names_refseq": "Pkd1l2", "protein_names_uniprotkb": "Polycystin-1-like protein 2; PC1-like 2 protein; Polycystic kidney disease protein 1-like 2", "protein_names_refseq": "polycystic kidney disease protein 1-like 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:113832959)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as a G-protein-coupled receptor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050982 detection of mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3V7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KB45-1", "uniprot_id": [ { "id": "A0A9J7KB45_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KB45", "type": "external" } ], "mass": 96448.0, "length": 839, "protein_name": "V-type proton ATPase subunit a", "gene_name": "Atp6v0a1", "organism": "Hamster", "refseq_name": "V-type proton ATPase 116 kDa subunit a1 isoform X1", "refseq_ac": [ { "id": "XP_035303212", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303212", "type": "external" } ], "gene_names_uniprotkb": "Atp6v0a1", "gene_names_refseq": "Atp6v0a1", "protein_names_uniprotkb": "V-type proton ATPase subunit a", "protein_names_refseq": "V-type proton ATPase 116 kDa subunit a1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100756648)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042470 melanosome;GO:0030665 clathrin-coated vesicle membrane;GO:0030672 synaptic vesicle membrane;GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain", "go_biological_process": "GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KB45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KB48-1", "uniprot_id": [ { "id": "A0A9J7KB48_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KB48", "type": "external" } ], "mass": 50478.0, "length": 452, "protein_name": "Ataxin-7-like protein 3", "gene_name": "Atxn7l3", "organism": "Hamster", "refseq_name": "ataxin-7-like protein 3 isoform X1", "refseq_ac": [ { "id": "XP_035303232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303232", "type": "external" } ], "gene_names_uniprotkb": "Atxn7l3; ATXN7L3", "gene_names_refseq": "Atxn7l3", "protein_names_uniprotkb": "Ataxin-7-like protein 3; SAGA-associated factor 11 homolog", "protein_names_refseq": "ataxin-7-like protein 3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754412)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0071819 DUBm complex;GO:0000124 SAGA complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KB48-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K833-1", "uniprot_id": [ { "id": "A0A9J7K833_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K833", "type": "external" } ], "mass": 130895.0, "length": 1152, "protein_name": "Nitric oxide synthase", "gene_name": "Nos2", "organism": "Hamster", "refseq_name": "nitric oxide synthase, inducible isoform X3", "refseq_ac": [ { "id": "XP_035303644", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303644", "type": "external" } ], "gene_names_uniprotkb": "Nos2", "gene_names_refseq": "Nos2", "protein_names_uniprotkb": "Nitric oxide synthase; 1.14.13.39", "protein_names_refseq": "nitric oxide synthase, inducible isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100760062)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Produces nitric oxide (NO) which is a messenger molecule with diverse functions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" } ], "go_molecular_function": "GO:0004517 nitric-oxide synthase activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0071222 cellular response to lipopolysaccharide;GO:0042742 defense response to bacterium;GO:0006809 nitric oxide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K833-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9Y1-1", "uniprot_id": [ { "id": "A0A9J7K9Y1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9Y1", "type": "external" } ], "mass": 36090.0, "length": 322, "protein_name": "Tumor necrosis factor ligand superfamily member 13", "gene_name": "LOC100758527", "organism": "Hamster", "refseq_name": "tumor necrosis factor ligand superfamily member 13 isoform X2", "refseq_ac": [ { "id": "XP_035303584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303584", "type": "external" } ], "gene_names_uniprotkb": "LOC100758527", "gene_names_refseq": "LOC100758527", "protein_names_uniprotkb": "Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand", "protein_names_refseq": "tumor necrosis factor ligand superfamily member 13 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758527)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion., [UniProtKB, UniProtKB, UniProtKB]; Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0006955 immune response;GO:0030154 cell differentiation;GO:0097191 extrinsic apoptotic signaling pathway;GO:0030890 positive regulation of B cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9Y1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K6P7-1", "uniprot_id": [ { "id": "A0A9J7K6P7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K6P7", "type": "external" } ], "mass": 33516.0, "length": 290, "protein_name": "Syntaxin-1B", "gene_name": "Stx1b", "organism": "Hamster", "refseq_name": "syntaxin-1B isoform X2", "refseq_ac": [ { "id": "XP_035298081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298081", "type": "external" } ], "gene_names_uniprotkb": "Stx1b", "gene_names_refseq": "Stx1b", "protein_names_uniprotkb": "Syntaxin-1B", "protein_names_refseq": "syntaxin-1B isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100754547)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding;GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0048787 presynaptic active zone membrane;GO:0030424 axon;GO:0031594 neuromuscular junction;GO:0008021 synaptic vesicle;GO:0031201 SNARE complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:2000463 positive regulation of excitatory postsynaptic potential;GO:0010468 regulation of gene expression;GO:0048791 calcium ion-regulated exocytosis of neurotransmitter;GO:0061669 spontaneous neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K6P7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFV4-1", "uniprot_id": [ { "id": "A0A9J7KFV4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFV4", "type": "external" } ], "mass": 70206.0, "length": 620, "protein_name": "Tyrosine-protein kinase", "gene_name": "LOC100767740", "organism": "Hamster", "refseq_name": "tyrosine-protein kinase ZAP-70 isoform X1", "refseq_ac": [ { "id": "XP_035301940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301940", "type": "external" } ], "gene_names_uniprotkb": "LOC100767740", "gene_names_refseq": "LOC100767740", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase ZAP-70 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100767740)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613687.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005911 cell-cell junction;GO:0042101 T cell receptor complex;GO:0045121 membrane raft;GO:0001772 immunological synapse", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response;GO:0045059 positive thymic T cell selection;GO:0045582 positive regulation of T cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KCW3-1", "uniprot_id": [ { "id": "A0A9J7KCW3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KCW3", "type": "external" } ], "mass": 19658.0, "length": 168, "protein_name": "Prostaglandin E synthase 3", "gene_name": "Ptges3", "organism": "Hamster", "refseq_name": "prostaglandin E synthase 3 isoform X2", "refseq_ac": [ { "id": "XP_035306771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306771", "type": "external" } ], "gene_names_uniprotkb": "Ptges3", "gene_names_refseq": "Ptges3", "protein_names_uniprotkb": "Prostaglandin E synthase 3; 5.3.99.3; Cytosolic prostaglandin E2 synthase; cPGES", "protein_names_refseq": "prostaglandin E synthase 3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774202)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" } ], "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0070182 DNA polymerase binding;GO:0051879 Hsp90 protein binding;GO:0050220 prostaglandin-E synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006457 protein folding;GO:0019371 cyclooxygenase pathway;GO:0051131 chaperone-mediated protein complex assembly;GO:0007004 telomere maintenance via telomerase;GO:1905323 telomerase holoenzyme complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KCW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9A8-1", "uniprot_id": [ { "id": "A0A9J7K9A8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9A8", "type": "external" } ], "mass": 151558.0, "length": 1320, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "gene_name": "Plcg1", "organism": "Hamster", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2", "refseq_ac": [ { "id": "XP_035302777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302777", "type": "external" } ], "gene_names_uniprotkb": "Plcg1", "gene_names_refseq": "Plcg1", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769697)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. Guanine nucleotide exchange factor that binds the GTPase DNM1 and catalyzes the dissociation of GDP, allowing a GTP molecule to bind in its place, therefore enhancing DNM1-dependent endocytosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" } ], "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0019901 protein kinase binding;GO:0005509 calcium ion binding;GO:0005168 neurotrophin TRKA receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0032587 ruffle membrane;GO:0008180 COP9 signalosome;GO:0005737 cytoplasm", "go_biological_process": "GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:0016477 cell migration;GO:0019722 calcium-mediated signaling;GO:0009395 phospholipid catabolic process;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9A8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFV8-1", "uniprot_id": [ { "id": "A0A9J7KFV8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFV8", "type": "external" } ], "mass": 38660.0, "length": 341, "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "Tssk4", "organism": "Hamster", "refseq_name": "testis-specific serine/threonine-protein kinase 4 isoform X1", "refseq_ac": [ { "id": "XP_007640864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640864", "type": "external" } ], "gene_names_uniprotkb": "Tssk4", "gene_names_refseq": "Tssk4", "protein_names_uniprotkb": "Testis-specific serine/threonine-protein kinase 4; 2.7.11.1", "protein_names_refseq": "testis-specific serine/threonine-protein kinase 4 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758937)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0050321 tau-protein kinase activity;GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031514 motile cilium;GO:0001669 acrosomal vesicle;GO:0036126 sperm flagellum", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000226 microtubule cytoskeleton organization;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0009566 fertilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFV8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3N8-1", "uniprot_id": [ { "id": "A0A9J7K3N8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3N8", "type": "external" } ], "mass": 1009660.0, "length": 8807, "protein_name": "Nesprin-1", "gene_name": "Syne1", "organism": "Hamster", "refseq_name": "nesprin-1 isoform X1", "refseq_ac": [ { "id": "XP_035296302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296302", "type": "external" } ], "gene_names_uniprotkb": "Syne1", "gene_names_refseq": "Syne1", "protein_names_uniprotkb": "Nesprin-1; Enaptin; KASH domain-containing protein 1; Myocyte nuclear envelope protein 1; Nuclear envelope spectrin repeat protein 1; Synaptic nuclear envelope protein 1", "protein_names_refseq": "nesprin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768768)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005640 nuclear outer membrane;GO:0005856 cytoskeleton;GO:0030017 sarcomere", "go_biological_process": "GO:1902017 regulation of cilium assembly;GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3N8-1", "record_type": "protein", "filter_code": "0000000.0000101.000010.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KA54-1", "uniprot_id": [ { "id": "A0A9J7KA54_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KA54", "type": "external" } ], "mass": 41615.0, "length": 391, "protein_name": "Ectodysplasin-A", "gene_name": "Eda", "organism": "Hamster", "refseq_name": "ectodysplasin-A isoform X2", "refseq_ac": [ { "id": "XP_035306073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306073", "type": "external" } ], "gene_names_uniprotkb": "Eda", "gene_names_refseq": "Eda", "protein_names_uniprotkb": "Ectodysplasin-A", "protein_names_refseq": "ectodysplasin-A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100768945)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0038177 death receptor agonist activity;GO:0005123 death receptor binding;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0048513 animal organ development;GO:0007166 cell surface receptor signaling pathway;GO:0030154 cell differentiation;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KA54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KCI9-1", "uniprot_id": [ { "id": "A0A9J7KCI9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KCI9", "type": "external" } ], "mass": 46581.0, "length": 419, "protein_name": "Voltage-gated potassium channel subunit beta-1", "gene_name": "Kcnab1", "organism": "Hamster", "refseq_name": "voltage-gated potassium channel subunit beta-1 isoform X1", "refseq_ac": [ { "id": "XP_035302731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302731", "type": "external" } ], "gene_names_uniprotkb": "Kcnab1", "gene_names_refseq": "Kcnab1", "protein_names_uniprotkb": "Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1", "protein_names_refseq": "voltage-gated potassium channel subunit beta-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100755538)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613691.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "1.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.2", "type": "external" }, { "id": "1.1.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.19", "type": "external" }, { "id": "1.1.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.20", "type": "external" }, { "id": "1.1.1.372", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.372", "type": "external" }, { "id": "1.1.1.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.54", "type": "external" }, { "id": "1.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.-.-", "type": "external" } ], "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0044325 transmembrane transporter binding;GO:0016491 oxidoreductase activity;GO:0005249 voltage-gated potassium channel activity;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008076 voltage-gated potassium channel complex;GO:0044224 juxtaparanode region of axon;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport;GO:0034220 monoatomic ion transmembrane transport;GO:0006813 potassium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KCI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KD33-1", "uniprot_id": [ { "id": "A0A9J7KD33_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KD33", "type": "external" } ], "mass": 69307.0, "length": 626, "protein_name": "Myelin-associated glycoprotein", "gene_name": "LOC113831770", "organism": "Hamster", "refseq_name": "myelin-associated glycoprotein isoform X3", "refseq_ac": [ { "id": "XP_035305435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305435", "type": "external" } ], "gene_names_uniprotkb": "LOC113831770", "gene_names_refseq": "LOC113831770", "protein_names_uniprotkb": "Myelin-associated glycoprotein", "protein_names_refseq": "myelin-associated glycoprotein isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:113831770)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0033691 sialic acid binding;GO:1905576 ganglioside GT1b binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035749 myelin sheath adaxonal region;GO:0043220 Schmidt-Lanterman incisure;GO:0045121 membrane raft", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KD33-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KE35-1", "uniprot_id": [ { "id": "A0A9J7KE35_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KE35", "type": "external" } ], "mass": 41887.0, "length": 371, "protein_name": "RT1 class I histocompatibility antigen, AA alpha chain-like isoform X1", "gene_name": "LOC118237718", "organism": "Hamster", "refseq_name": "RT1 class I histocompatibility antigen, AA alpha chain-like isoform X1", "refseq_ac": [ { "id": "XP_035306824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306824", "type": "external" } ], "gene_names_uniprotkb": "LOC118237718", "gene_names_refseq": "LOC118237718", "protein_names_uniprotkb": "RT1 class I histocompatibility antigen, AA alpha chain-like isoform X1", "protein_names_refseq": "RT1 class I histocompatibility antigen, AA alpha chain-like isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:118237718)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0042612 MHC class I protein complex;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0006955 immune response;GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0001916 positive regulation of T cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KE35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K385-1", "uniprot_id": [ { "id": "A0A9J7K385_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K385", "type": "external" } ], "mass": 27470.0, "length": 242, "protein_name": "Popy Class I histocompatibility antigen, A-1 alpha chain-like isoform X2", "gene_name": "LOC100757524", "organism": "Hamster", "refseq_name": "popy Class I histocompatibility antigen, A-1 alpha chain-like isoform X2", "refseq_ac": [ { "id": "XP_035307309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307309", "type": "external" } ], "gene_names_uniprotkb": "LOC100757524", "gene_names_refseq": "LOC100757524", "protein_names_uniprotkb": "Popy Class I histocompatibility antigen, A-1 alpha chain-like isoform X2", "protein_names_refseq": "popy Class I histocompatibility antigen, A-1 alpha chain-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100757524)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 12% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the presentation of foreign antigens to the immune system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0042612 MHC class I protein complex;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0006955 immune response;GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0001916 positive regulation of T cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K385-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K396-1", "uniprot_id": [ { "id": "A0A9J7K396_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K396", "type": "external" } ], "mass": 21819.0, "length": 197, "protein_name": "Pyridoxal kinase", "gene_name": "LOC100751202", "organism": "Hamster", "refseq_name": "pyridoxal kinase isoform X2", "refseq_ac": [ { "id": "XP_035307363", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307363", "type": "external" } ], "gene_names_uniprotkb": "LOC100751202", "gene_names_refseq": "LOC100751202", "protein_names_uniprotkb": "Pyridoxal kinase; 2.7.1.35; Pyridoxine kinase", "protein_names_refseq": "pyridoxal kinase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100751202)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively. PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008478 pyridoxal kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0009443 pyridoxal 5'-phosphate salvage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K396-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3A2-1", "uniprot_id": [ { "id": "A0A9J7K3A2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3A2", "type": "external" } ], "mass": 40179.0, "length": 360, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113838175", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027289802", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289802", "type": "external" } ], "gene_names_uniprotkb": "LOC113838175", "gene_names_refseq": "LOC113838175", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838175)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K3A2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3A9-1", "uniprot_id": [ { "id": "A0A9J7K3A9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3A9", "type": "external" } ], "mass": 58122.0, "length": 524, "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "Tm7sf2", "organism": "Hamster", "refseq_name": "delta(14)-sterol reductase TM7SF2 isoform X1", "refseq_ac": [ { "id": "XP_035293801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293801", "type": "external" } ], "gene_names_uniprotkb": "Tm7sf2", "gene_names_refseq": "Tm7sf2", "protein_names_uniprotkb": "Delta(14)-sterol reductase TM7SF2; 1.3.1.70; 3-beta-hydroxysterol Delta (14)-reductase; C-14 sterol reductase; Delta-14-SR; Sterol C14-reductase; Transmembrane 7 superfamily member 2", "protein_names_refseq": "delta(14)-sterol reductase TM7SF2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100766362)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616756.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.70", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.70", "type": "external" } ], "go_molecular_function": "GO:0050613 Delta14-sterol reductase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3A9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3B8-1", "uniprot_id": [ { "id": "A0A9J7K3B8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3B8", "type": "external" } ], "mass": 56253.0, "length": 491, "protein_name": "Cytochrome P450", "gene_name": "LOC113838302", "organism": "Hamster", "refseq_name": "cytochrome P450 2B1-like", "refseq_ac": [ { "id": "XP_027289875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289875", "type": "external" } ], "gene_names_uniprotkb": "LOC113838302", "gene_names_refseq": "LOC113838302", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.1", "protein_names_refseq": "cytochrome P450 2B1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838302)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008392 arachidonate epoxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3B8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3F3-1", "uniprot_id": [ { "id": "A0A9J7K3F3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3F3", "type": "external" } ], "mass": 52370.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838725", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like isoform X3", "refseq_ac": [ { "id": "XP_027290075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290075", "type": "external" } ], "gene_names_uniprotkb": "LOC113838725", "gene_names_refseq": "LOC113838725", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:113838725)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027290075.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K3F3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3F5-1", "uniprot_id": [ { "id": "A0A9J7K3F5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3F5", "type": "external" } ], "mass": 110181.0, "length": 1033, "protein_name": "Platelet endothelial aggregation receptor 1", "gene_name": "Pear1", "organism": "Hamster", "refseq_name": "platelet endothelial aggregation receptor 1", "refseq_ac": [ { "id": "XP_035307598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307598", "type": "external" } ], "gene_names_uniprotkb": "Pear1", "gene_names_refseq": "Pear1", "protein_names_uniprotkb": "Platelet endothelial aggregation receptor 1; Multiple epidermal growth factor-like domains protein 12", "protein_names_refseq": "platelet endothelial aggregation receptor 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100750684)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for SVEP1-mediated platelet activation, via its interaction with SVEP1 and subsequent activation of AKT/mTOR signaling. May be involved in the early stages of hematopoiesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:0010572 positive regulation of platelet activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3F5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3J5-1", "uniprot_id": [ { "id": "A0A9J7K3J5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3J5", "type": "external" } ], "mass": 163767.0, "length": 1460, "protein_name": "RNA uridylyltransferase", "gene_name": "LOC118237711", "organism": "Hamster", "refseq_name": "terminal uridylyltransferase 4-like", "refseq_ac": [ { "id": "XP_027290318", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290318", "type": "external" } ], "gene_names_uniprotkb": "LOC118237711", "gene_names_refseq": "LOC118237711", "protein_names_uniprotkb": "RNA uridylyltransferase; 2.7.7.52", "protein_names_refseq": "terminal uridylyltransferase 4-like", "tax_id": 10029, "disease": "", "pathway": " (cge:118237711)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277308.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027290318.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" }, { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0050265 RNA uridylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0001556 oocyte maturation;GO:0010586 miRNA metabolic process;GO:0031123 RNA 3'-end processing;GO:1990074 polyuridylation-dependent mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K3J5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3L9-1", "uniprot_id": [ { "id": "A0A9J7K3L9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3L9", "type": "external" } ], "mass": 63087.0, "length": 562, "protein_name": "Calcium-binding mitochondrial carrier protein SCaMC-1 isoform X2", "gene_name": "LOC100753868", "organism": "Hamster", "refseq_name": "calcium-binding mitochondrial carrier protein SCaMC-1 isoform X2", "refseq_ac": [ { "id": "XP_035307810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307810", "type": "external" } ], "gene_names_uniprotkb": "LOC100753868", "gene_names_refseq": "LOC100753868", "protein_names_uniprotkb": "Calcium-binding mitochondrial carrier protein SCaMC-1 isoform X2", "protein_names_refseq": "calcium-binding mitochondrial carrier protein SCaMC-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100753868)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3L9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3M6-1", "uniprot_id": [ { "id": "A0A9J7K3M6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3M6", "type": "external" } ], "mass": 43782.0, "length": 402, "protein_name": "Tyrosine-protein phosphatase non-receptor type substrate 1", "gene_name": "LOC100773652", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: signal-regulatory protein beta-1 isoform X2", "refseq_ac": [ { "id": "XP_035294595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294595", "type": "external" } ], "gene_names_uniprotkb": "LOC100773652", "gene_names_refseq": "LOC100773652", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type substrate 1; Brain Ig-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-1", "protein_names_refseq": "LOW QUALITY PROTEIN: signal-regulatory protein beta-1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773652)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases frameshifts :: corrected 4 indels internal stop codons :: corrected 4 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0032675 regulation of interleukin-6 production;GO:0050765 negative regulation of phagocytosis;GO:0032680 regulation of tumor necrosis factor production;GO:0045428 regulation of nitric oxide biosynthetic process;GO:0097529 myeloid leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3M6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3N1-1", "uniprot_id": [ { "id": "A0A9J7K3N1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3N1", "type": "external" } ], "mass": 38599.0, "length": 349, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC118237634", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_027290116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290116", "type": "external" } ], "gene_names_uniprotkb": "LOC118237634", "gene_names_refseq": "LOC118237634", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:118237634)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K3N1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3P1-1", "uniprot_id": [ { "id": "A0A9J7K3P1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3P1", "type": "external" } ], "mass": 40150.0, "length": 360, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC100758918", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: nucleoporin SEH1-like isoform X2", "refseq_ac": [ { "id": "XP_027290175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290175", "type": "external" } ], "gene_names_uniprotkb": "LOC100758918", "gene_names_refseq": "LOC100758918", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "LOW QUALITY PROTEIN: nucleoporin SEH1-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758918)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276930.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K3P1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3P4-1", "uniprot_id": [ { "id": "A0A9J7K3P4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3P4", "type": "external" } ], "mass": 80622.0, "length": 720, "protein_name": "Neuroendocrine convertase 1", "gene_name": "Pcsk1", "organism": "Hamster", "refseq_name": "neuroendocrine convertase 1", "refseq_ac": [ { "id": "XP_035294667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294667", "type": "external" } ], "gene_names_uniprotkb": "Pcsk1", "gene_names_refseq": "Pcsk1", "protein_names_uniprotkb": "Neuroendocrine convertase 1; 3.4.21.93; Prohormone convertase 1; Proprotein convertase 1", "protein_names_refseq": "neuroendocrine convertase 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757402)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0043005 neuron projection;GO:0030133 transport vesicle", "go_biological_process": "GO:0016486 peptide hormone processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3P4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3Q4-1", "uniprot_id": [ { "id": "A0A9J7K3Q4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3Q4", "type": "external" } ], "mass": 30855.0, "length": 277, "protein_name": "Ephrin-B2", "gene_name": "LOC113838971", "organism": "Hamster", "refseq_name": "ephrin-B2-like", "refseq_ac": [ { "id": "XP_027290260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027290260", "type": "external" } ], "gene_names_uniprotkb": "LOC113838971", "gene_names_refseq": "LOC113838971", "protein_names_uniprotkb": "Ephrin-B2; EPH-related receptor tyrosine kinase ligand 5; HTK ligand", "protein_names_refseq": "ephrin-B2-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838971)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277422.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K3Q4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3V9-1", "uniprot_id": [ { "id": "A0A9J7K3V9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3V9", "type": "external" } ], "mass": 59802.0, "length": 523, "protein_name": "Beta-galactoside alpha-2,6-sialyltransferase 2", "gene_name": "St6gal2", "organism": "Hamster", "refseq_name": "beta-galactoside alpha-2,6-sialyltransferase 2", "refseq_ac": [ { "id": "XP_035308144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308144", "type": "external" } ], "gene_names_uniprotkb": "St6gal2", "gene_names_refseq": "St6gal2", "protein_names_uniprotkb": "Beta-galactoside alpha-2,6-sialyltransferase 2; 2.4.3.1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2; ST6Gal II; Sialyltransferase 2", "protein_names_refseq": "beta-galactoside alpha-2,6-sialyltransferase 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763756)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.1", "type": "external" } ], "go_molecular_function": "GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0097503 sialylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3V9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3W3-1", "uniprot_id": [ { "id": "A0A9J7K3W3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3W3", "type": "external" } ], "mass": 32480.0, "length": 302, "protein_name": "Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2", "gene_name": "Hey1", "organism": "Hamster", "refseq_name": "hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2", "refseq_ac": [ { "id": "XP_035294892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294892", "type": "external" } ], "gene_names_uniprotkb": "Hey1", "gene_names_refseq": "Hey1", "protein_names_uniprotkb": "Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2", "protein_names_refseq": "hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752534)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0014706 striated muscle tissue development;GO:0048729 tissue morphogenesis;GO:0003208 cardiac ventricle morphogenesis;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3W3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3X7-1", "uniprot_id": [ { "id": "A0A9J7K3X7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3X7", "type": "external" } ], "mass": 23203.0, "length": 198, "protein_name": "High mobility group protein B1-like", "gene_name": "LOC100761755", "organism": "Hamster", "refseq_name": "high mobility group protein B1-like", "refseq_ac": [ { "id": "XP_035298663", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298663", "type": "external" } ], "gene_names_uniprotkb": "LOC100761755", "gene_names_refseq": "LOC100761755", "protein_names_uniprotkb": "High mobility group protein B1-like", "protein_names_refseq": "high mobility group protein B1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100761755)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; In the cytoplasm proposed to dissociate the BECN1:BCL2 complex via competitive interaction with BECN1 leading to autophagy activation. Can protect BECN1 and ATG5 from calpain-mediated cleavage and thus proposed to control their proautophagic and proapoptotic functions and to regulate the extent and severity of inflammation-associated cellular injury. In myeloid cells has a protective role against endotoxemia and bacterial infection by promoting autophagy. Involved in endosomal translocation and activation of TLR9 in response to CpG-DNA in macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008201 heparin binding;GO:0008289 lipid binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3X7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K3Z1-1", "uniprot_id": [ { "id": "A0A9J7K3Z1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K3Z1", "type": "external" } ], "mass": 400157.0, "length": 3629, "protein_name": "Cubilin", "gene_name": "Cubn", "organism": "Hamster", "refseq_name": "cubilin isoform X2", "refseq_ac": [ { "id": "XP_035298709", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298709", "type": "external" } ], "gene_names_uniprotkb": "Cubn", "gene_names_refseq": "Cubn", "protein_names_uniprotkb": "Cubilin; Intrinsic factor-cobalamin receptor", "protein_names_refseq": "cubilin isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774474)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005905 clathrin-coated pit;GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0015031 protein transport;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K3Z1-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4F7-1", "uniprot_id": [ { "id": "A0A9J7K4F7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4F7", "type": "external" } ], "mass": 156385.0, "length": 1421, "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plch2", "organism": "Hamster", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "refseq_ac": [ { "id": "XP_035295235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295235", "type": "external" } ], "gene_names_uniprotkb": "Plch2", "gene_names_refseq": "Plch2", "protein_names_uniprotkb": "Phosphoinositide phospholipase C; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769053)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" } ], "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0051209 release of sequestered calcium ion into cytosol;GO:0048015 phosphatidylinositol-mediated signaling;GO:0046488 phosphatidylinositol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4F7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4H5-1", "uniprot_id": [ { "id": "A0A9J7K4H5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4H5", "type": "external" } ], "mass": 53977.0, "length": 470, "protein_name": "L-gulonolactone oxidase", "gene_name": "LOC100760306", "organism": "Hamster", "refseq_name": "L-gulonolactone oxidase", "refseq_ac": [ { "id": "XP_035308999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308999", "type": "external" } ], "gene_names_uniprotkb": "LOC100760306", "gene_names_refseq": "LOC100760306", "protein_names_uniprotkb": "L-gulonolactone oxidase; 1.1.3.8; LGO", "protein_names_refseq": "L-gulonolactone oxidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100760306)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.8", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0003885 D-arabinono-1,4-lactone oxidase activity;GO:0050105 L-gulonolactone oxidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0019853 L-ascorbic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4H5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4K9-1", "uniprot_id": [ { "id": "A0A9J7K4K9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4K9", "type": "external" } ], "mass": 81013.0, "length": 723, "protein_name": "Protein spire homolog 2 isoform X2", "gene_name": "Spire2", "organism": "Hamster", "refseq_name": "protein spire homolog 2 isoform X2", "refseq_ac": [ { "id": "XP_035297359", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297359", "type": "external" } ], "gene_names_uniprotkb": "Spire2", "gene_names_refseq": "Spire2", "protein_names_uniprotkb": "Protein spire homolog 2 isoform X2", "protein_names_refseq": "protein spire homolog 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100760932)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0030041 actin filament polymerization;GO:0051639 actin filament network formation;GO:0045010 actin nucleation;GO:0048193 Golgi vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4K9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K636-1", "uniprot_id": [ { "id": "A0A9J7K636_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K636", "type": "external" } ], "mass": 116545.0, "length": 1052, "protein_name": "Rho family-interacting cell polarization regulator 2", "gene_name": "Ripor2", "organism": "Hamster", "refseq_name": "rho family-interacting cell polarization regulator 2 isoform X1", "refseq_ac": [ { "id": "XP_035297406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297406", "type": "external" } ], "gene_names_uniprotkb": "Ripor2", "gene_names_refseq": "Ripor2", "protein_names_uniprotkb": "Rho family-interacting cell polarization regulator 2", "protein_names_refseq": "rho family-interacting cell polarization regulator 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100763872)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear. Plays a role for maintaining the structural organization of the basal domain of stereocilia. Involved in mechanosensory hair cell function. Required for normal hearing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0016324 apical plasma membrane;GO:0030175 filopodium;GO:0060171 stereocilium membrane", "go_biological_process": "GO:0006935 chemotaxis;GO:0007155 cell adhesion;GO:0030154 cell differentiation;GO:0007517 muscle organ development;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K636-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4N1-1", "uniprot_id": [ { "id": "A0A9J7K4N1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4N1", "type": "external" } ], "mass": 181478.0, "length": 1606, "protein_name": "Centrosomal protein of 164 kDa", "gene_name": "Cep164", "organism": "Hamster", "refseq_name": "centrosomal protein of 164 kDa isoform X3", "refseq_ac": [ { "id": "XP_035299527", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299527", "type": "external" } ], "gene_names_uniprotkb": "Cep164", "gene_names_refseq": "Cep164", "protein_names_uniprotkb": "Centrosomal protein of 164 kDa", "protein_names_refseq": "centrosomal protein of 164 kDa isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100762565)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005814 centriole;GO:0097539 ciliary transition fiber", "go_biological_process": "GO:0006281 DNA repair;GO:0051301 cell division;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4N1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4N6-1", "uniprot_id": [ { "id": "A0A9J7K4N6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4N6", "type": "external" } ], "mass": 148461.0, "length": 1336, "protein_name": "Serine/threonine-protein kinase SIK3", "gene_name": "Sik3", "organism": "Hamster", "refseq_name": "serine/threonine-protein kinase SIK3 isoform X10", "refseq_ac": [ { "id": "XP_035299542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299542", "type": "external" } ], "gene_names_uniprotkb": "Sik3", "gene_names_refseq": "Sik3", "protein_names_uniprotkb": "Serine/threonine-protein kinase SIK3; 2.7.11.1; Salt-inducible kinase 3; Serine/threonine-protein kinase QSK", "protein_names_refseq": "serine/threonine-protein kinase SIK3 isoform X10", "tax_id": 10029, "disease": "", "pathway": " (cge:100774415)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0050321 tau-protein kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4N6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4P0-1", "uniprot_id": [ { "id": "A0A9J7K4P0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4P0", "type": "external" } ], "mass": 26037.0, "length": 233, "protein_name": "Insulin-like growth factor 2", "gene_name": "Igf2", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: insulin-like growth factor II isoform X2", "refseq_ac": [ { "id": "XP_035297453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297453", "type": "external" } ], "gene_names_uniprotkb": "Igf2", "gene_names_refseq": "Igf2", "protein_names_uniprotkb": "Insulin-like growth factor 2; Insulin-like growth factor II; Multiplication-stimulating polypeptide", "protein_names_refseq": "LOW QUALITY PROTEIN: insulin-like growth factor II isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100762359)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Preptin undergoes glucose-mediated co-secretion with insulin, and acts as a physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3., [UniProtKB, UniProtKB]; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005159 insulin-like growth factor receptor binding;GO:0005179 hormone activity;GO:0008083 growth factor activity;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006006 glucose metabolic process;GO:0051781 positive regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4P0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4Q3-1", "uniprot_id": [ { "id": "A0A9J7K4Q3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4Q3", "type": "external" } ], "mass": 126225.0, "length": 1096, "protein_name": "Sodium leak channel NALCN", "gene_name": "LOC100761462", "organism": "Hamster", "refseq_name": "sodium leak channel non-selective protein", "refseq_ac": [ { "id": "XP_035309262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309262", "type": "external" } ], "gene_names_uniprotkb": "LOC100761462", "gene_names_refseq": "LOC100761462", "protein_names_uniprotkb": "Sodium leak channel NALCN; Sodium leak channel non-selective protein; Voltage gated channel-like protein 1", "protein_names_refseq": "sodium leak channel non-selective protein", "tax_id": 10029, "disease": "", "pathway": " (cge:100761462)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005272 sodium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0032224 positive regulation of synaptic transmission, cholinergic;GO:0032230 positive regulation of synaptic transmission, GABAergic", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K4Q3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K4Z0-1", "uniprot_id": [ { "id": "A0A9J7K4Z0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K4Z0", "type": "external" } ], "mass": 37623.0, "length": 334, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC113838012", "organism": "Hamster", "refseq_name": "nucleoporin SEH1-like", "refseq_ac": [ { "id": "XP_035309551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309551", "type": "external" } ], "gene_names_uniprotkb": "LOC113838012", "gene_names_refseq": "LOC113838012", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "nucleoporin SEH1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838012)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K4Z0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K539-1", "uniprot_id": [ { "id": "A0A9J7K539_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K539", "type": "external" } ], "mass": 57928.0, "length": 499, "protein_name": "E3 ubiquitin-protein ligase TRIM39", "gene_name": "LOC113832515", "organism": "Hamster", "refseq_name": "E3 ubiquitin-protein ligase TRIM39 isoform X1", "refseq_ac": [ { "id": "XP_035306465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306465", "type": "external" } ], "gene_names_uniprotkb": "LOC113832515; LOC100761321", "gene_names_refseq": "LOC100761321", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM39; 2.3.2.27; RING-type E3 ubiquitin transferase TRIM39; Tripartite motif-containing protein 39", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM39 isoform X1", "tax_id": 10029, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21. Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K539-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K543-1", "uniprot_id": [ { "id": "A0A9J7K543_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K543", "type": "external" } ], "mass": 182296.0, "length": 1623, "protein_name": "RNA uridylyltransferase", "gene_name": "LOC107977733", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: terminal uridylyltransferase 4-like isoform X2", "refseq_ac": [ { "id": "XP_035309775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309775", "type": "external" } ], "gene_names_uniprotkb": "LOC107977733", "gene_names_refseq": "LOC107977733", "protein_names_uniprotkb": "RNA uridylyltransferase; 2.7.7.52", "protein_names_refseq": "LOW QUALITY PROTEIN: terminal uridylyltransferase 4-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107977733)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases internal stop codons :: corrected 2 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277308.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" }, { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0050265 RNA uridylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0001556 oocyte maturation;GO:0010586 miRNA metabolic process;GO:0031123 RNA 3'-end processing;GO:1990074 polyuridylation-dependent mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7K543-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K5H0-1", "uniprot_id": [ { "id": "A0A9J7K5H0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K5H0", "type": "external" } ], "mass": 64689.0, "length": 583, "protein_name": "Vesicular glutamate transporter 2 isoform X2", "gene_name": "Slc17a6", "organism": "Hamster", "refseq_name": "vesicular glutamate transporter 2 isoform X2", "refseq_ac": [ { "id": "XP_035298385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298385", "type": "external" } ], "gene_names_uniprotkb": "Slc17a6", "gene_names_refseq": "Slc17a6", "protein_names_uniprotkb": "Vesicular glutamate transporter 2 isoform X2", "protein_names_refseq": "vesicular glutamate transporter 2 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773912)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015293 symporter activity;GO:0015297 antiporter activity;GO:0005254 chloride channel activity;GO:0140788 L-glutamate uniporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0030672 synaptic vesicle membrane;GO:0034707 chloride channel complex;GO:0060076 excitatory synapse", "go_biological_process": "GO:0050803 regulation of synapse structure or activity;GO:0035249 synaptic transmission, glutamatergic;GO:0006814 sodium ion transport;GO:0006817 phosphate ion transport;GO:0098700 neurotransmitter loading into synaptic vesicle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K5H0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K5I0-1", "uniprot_id": [ { "id": "A0A9J7K5I0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K5I0", "type": "external" } ], "mass": 93324.0, "length": 850, "protein_name": "FYN-binding protein 1", "gene_name": "Fyb1", "organism": "Hamster", "refseq_name": "FYN-binding protein 1", "refseq_ac": [ { "id": "XP_035296483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035296483", "type": "external" } ], "gene_names_uniprotkb": "Fyb1", "gene_names_refseq": "Fyb1", "protein_names_uniprotkb": "FYN-binding protein 1; Adhesion and degranulation promoting adaptor protein; FYB-120/130; FYN-T-binding protein; SLAP-130; SLP-76-associated phosphoprotein", "protein_names_refseq": "FYN-binding protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774387)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0072659 protein localization to plasma membrane;GO:0050852 T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K5I0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K5S1-1", "uniprot_id": [ { "id": "A0A9J7K5S1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K5S1", "type": "external" } ], "mass": 38933.0, "length": 355, "protein_name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "gene_name": "Ilkap", "organism": "Hamster", "refseq_name": "integrin-linked kinase-associated serine/threonine phosphatase 2C isoform X3", "refseq_ac": [ { "id": "XP_035297027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297027", "type": "external" } ], "gene_names_uniprotkb": "Ilkap", "gene_names_refseq": "Ilkap", "protein_names_uniprotkb": "Integrin-linked kinase-associated serine/threonine phosphatase 2C; 3.1.3.16", "protein_names_refseq": "integrin-linked kinase-associated serine/threonine phosphatase 2C isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100773641)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K5S1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K5Z0-1", "uniprot_id": [ { "id": "A0A9J7K5Z0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K5Z0", "type": "external" } ], "mass": 132627.0, "length": 1178, "protein_name": "Cytosolic carboxypeptidase 1", "gene_name": "Agtpbp1", "organism": "Hamster", "refseq_name": "cytosolic carboxypeptidase 1 isoform X2", "refseq_ac": [ { "id": "XP_035298908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298908", "type": "external" } ], "gene_names_uniprotkb": "Agtpbp1", "gene_names_refseq": "Agtpbp1", "protein_names_uniprotkb": "Cytosolic carboxypeptidase 1; 3.4.17.24; ATP/GTP-binding protein 1; Protein deglutamylase CCP1", "protein_names_refseq": "cytosolic carboxypeptidase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100772683)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.17.24", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.24", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K5Z0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K676-1", "uniprot_id": [ { "id": "A0A9J7K676_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K676", "type": "external" } ], "mass": 115038.0, "length": 1037, "protein_name": "Outer dynein arm-docking complex subunit 2", "gene_name": "Armc4", "organism": "Hamster", "refseq_name": "armadillo repeat-containing protein 4", "refseq_ac": [ { "id": "XP_035297364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297364", "type": "external" } ], "gene_names_uniprotkb": "Armc4", "gene_names_refseq": "Armc4", "protein_names_uniprotkb": "Outer dynein arm-docking complex subunit 2; Armadillo repeat-containing protein 4", "protein_names_refseq": "armadillo repeat-containing protein 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100773009)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005930 axoneme", "go_biological_process": "GO:0007368 determination of left/right symmetry;GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K676-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K6B1-1", "uniprot_id": [ { "id": "A0A9J7K6B1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K6B1", "type": "external" } ], "mass": 123660.0, "length": 1140, "protein_name": "Myelin regulatory factor", "gene_name": "Myrf", "organism": "Hamster", "refseq_name": "myelin regulatory factor isoform X2", "refseq_ac": [ { "id": "XP_035297477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297477", "type": "external" } ], "gene_names_uniprotkb": "Myrf", "gene_names_refseq": "Myrf", "protein_names_uniprotkb": "Myelin regulatory factor; Myelin gene regulatory factor", "protein_names_refseq": "myelin regulatory factor isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756693)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes., [UniProtKB, UniProtKB]; Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage., [UniProtKB, UniProtKB]; Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG, DUSP15 and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0016540 protein autoprocessing;GO:0032286 central nervous system myelin maintenance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K6B1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K6F5-1", "uniprot_id": [ { "id": "A0A9J7K6F5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K6F5", "type": "external" } ], "mass": 43741.0, "length": 389, "protein_name": "L-selectin", "gene_name": "Sell", "organism": "Hamster", "refseq_name": "L-selectin", "refseq_ac": [ { "id": "XP_035301707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301707", "type": "external" } ], "gene_names_uniprotkb": "Sell", "gene_names_refseq": "Sell", "protein_names_uniprotkb": "L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 1; Lymph node homing receptor", "protein_names_refseq": "L-selectin", "tax_id": 10029, "disease": "", "pathway": " (cge:100763803)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0050900 leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K6F5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K705-1", "uniprot_id": [ { "id": "A0A9J7K705_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K705", "type": "external" } ], "mass": 34050.0, "length": 304, "protein_name": "Junctional adhesion molecule C", "gene_name": "Jam3", "organism": "Hamster", "refseq_name": "junctional adhesion molecule C", "refseq_ac": [ { "id": "XP_035300094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300094", "type": "external" } ], "gene_names_uniprotkb": "Jam3", "gene_names_refseq": "Jam3", "protein_names_uniprotkb": "Junctional adhesion molecule C; Junctional adhesion molecule 3", "protein_names_refseq": "junctional adhesion molecule C", "tax_id": 10029, "disease": "", "pathway": " (cge:100758045)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes chemotaxis of vascular endothelial cells and stimulates angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0044291 cell-cell contact zone;GO:0098636 protein complex involved in cell adhesion", "go_biological_process": "GO:0048731 system development;GO:0007283 spermatogenesis;GO:0016477 cell migration;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K705-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K747-1", "uniprot_id": [ { "id": "A0A9J7K747_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K747", "type": "external" } ], "mass": 30246.0, "length": 277, "protein_name": "Epidermal growth factor-like protein 7", "gene_name": "Egfl7", "organism": "Hamster", "refseq_name": "epidermal growth factor-like protein 7 isoform X1", "refseq_ac": [ { "id": "XP_035293981", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293981", "type": "external" } ], "gene_names_uniprotkb": "Egfl7", "gene_names_refseq": "Egfl7", "protein_names_uniprotkb": "Epidermal growth factor-like protein 7; Multiple epidermal growth factor-like domains protein 7", "protein_names_refseq": "epidermal growth factor-like protein 7 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100753992)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617120.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K747-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K798-1", "uniprot_id": [ { "id": "A0A9J7K798_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K798", "type": "external" } ], "mass": 136606.0, "length": 1214, "protein_name": "Zinc finger E-box-binding homeobox 2", "gene_name": "Zeb2", "organism": "Hamster", "refseq_name": "zinc finger E-box-binding homeobox 2 isoform X3", "refseq_ac": [ { "id": "XP_035302705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302705", "type": "external" } ], "gene_names_uniprotkb": "Zeb2", "gene_names_refseq": "Zeb2", "protein_names_uniprotkb": "Zinc finger E-box-binding homeobox 2; Smad-interacting protein 1; Zinc finger homeobox protein 1b", "protein_names_refseq": "zinc finger E-box-binding homeobox 2 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100752455)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048023 positive regulation of melanin biosynthetic process;GO:0030177 positive regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K798-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K7W3-1", "uniprot_id": [ { "id": "A0A9J7K7W3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K7W3", "type": "external" } ], "mass": 209994.0, "length": 1851, "protein_name": "Voltage-dependent L-type calcium channel subunit alpha", "gene_name": "Cacna1s", "organism": "Hamster", "refseq_name": "voltage-dependent L-type calcium channel subunit alpha-1S isoform X3", "refseq_ac": [ { "id": "XP_035301099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301099", "type": "external" } ], "gene_names_uniprotkb": "Cacna1s", "gene_names_refseq": "Cacna1s", "protein_names_uniprotkb": "Voltage-dependent L-type calcium channel subunit alpha", "protein_names_refseq": "voltage-dependent L-type calcium channel subunit alpha-1S isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100765508)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca(2+) release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008331 high voltage-gated calcium channel activity", "go_cellular_component": "GO:0030315 T-tubule;GO:0005891 voltage-gated calcium channel complex", "go_biological_process": "GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K7W3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K7W9-1", "uniprot_id": [ { "id": "A0A9J7K7W9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K7W9", "type": "external" } ], "mass": 81064.0, "length": 718, "protein_name": "Myeloperoxidase", "gene_name": "Mpo", "organism": "Hamster", "refseq_name": "myeloperoxidase", "refseq_ac": [ { "id": "XP_035303436", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303436", "type": "external" } ], "gene_names_uniprotkb": "Mpo", "gene_names_refseq": "Mpo", "protein_names_uniprotkb": "Myeloperoxidase; 1.11.2.2", "protein_names_refseq": "myeloperoxidase", "tax_id": 10029, "disease": "", "pathway": " (cge:100752227)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0042742 defense response to bacterium;GO:0042744 hydrogen peroxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K7W9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K801-1", "uniprot_id": [ { "id": "A0A9J7K801_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K801", "type": "external" } ], "mass": 123575.0, "length": 1067, "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "Smc6", "organism": "Hamster", "refseq_name": "structural maintenance of chromosomes protein 6 isoform X5", "refseq_ac": [ { "id": "XP_035303540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303540", "type": "external" } ], "gene_names_uniprotkb": "Smc6", "gene_names_refseq": "Smc6", "protein_names_uniprotkb": "Structural maintenance of chromosomes protein 6", "protein_names_refseq": "structural maintenance of chromosomes protein 6 isoform X5", "tax_id": 10029, "disease": "", "pathway": " (cge:100757987)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0016605 PML body;GO:0035861 site of double-strand break;GO:0000781 chromosome, telomeric region;GO:0030915 Smc5-Smc6 complex", "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K801-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K8N6-1", "uniprot_id": [ { "id": "A0A9J7K8N6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K8N6", "type": "external" } ], "mass": 172338.0, "length": 1569, "protein_name": "Synaptojanin-1", "gene_name": "Synj1", "organism": "Hamster", "refseq_name": "synaptojanin-1 isoform X1", "refseq_ac": [ { "id": "XP_035300213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300213", "type": "external" } ], "gene_names_uniprotkb": "Synj1", "gene_names_refseq": "Synj1", "protein_names_uniprotkb": "Synaptojanin-1; 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1", "protein_names_refseq": "synaptojanin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100757174)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0017124 SH3 domain binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0030118 clathrin coat;GO:0048471 perinuclear region of cytoplasm;GO:0098793 presynapse", "go_biological_process": "GO:0048259 regulation of receptor-mediated endocytosis;GO:0046856 phosphatidylinositol dephosphorylation;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K8N6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K8S3-1", "uniprot_id": [ { "id": "A0A9J7K8S3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K8S3", "type": "external" } ], "mass": 33390.0, "length": 315, "protein_name": "Mitochondrial glutamate carrier 2", "gene_name": "Slc25a18", "organism": "Hamster", "refseq_name": "mitochondrial glutamate carrier 2", "refseq_ac": [ { "id": "XP_035304472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304472", "type": "external" } ], "gene_names_uniprotkb": "Slc25a18", "gene_names_refseq": "Slc25a18", "protein_names_uniprotkb": "Mitochondrial glutamate carrier 2; Glutamate/H(+) symporter 2; Solute carrier family 25 member 18", "protein_names_refseq": "mitochondrial glutamate carrier 2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756941)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0043490 malate-aspartate shuttle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K8S3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K8X5-1", "uniprot_id": [ { "id": "A0A9J7K8X5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K8X5", "type": "external" } ], "mass": 232754.0, "length": 2127, "protein_name": "Plexin-B1", "gene_name": "Plxnb1", "organism": "Hamster", "refseq_name": "plexin-B1 isoform X1", "refseq_ac": [ { "id": "XP_035300475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300475", "type": "external" } ], "gene_names_uniprotkb": "Plxnb1", "gene_names_refseq": "Plxnb1", "protein_names_uniprotkb": "Plexin-B1", "protein_names_refseq": "plexin-B1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100762729)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017154 semaphorin receptor activity;GO:0032794 GTPase activating protein binding", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0007162 negative regulation of cell adhesion;GO:0030334 regulation of cell migration;GO:0008360 regulation of cell shape;GO:0050772 positive regulation of axonogenesis;GO:0043931 ossification involved in bone maturation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K8X5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K8Y1-1", "uniprot_id": [ { "id": "A0A9J7K8Y1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K8Y1", "type": "external" } ], "mass": 150822.0, "length": 1424, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Lmtk3", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: serine/threonine-protein kinase LMTK3 isoform X2", "refseq_ac": [ { "id": "XP_035302343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302343", "type": "external" } ], "gene_names_uniprotkb": "Lmtk3", "gene_names_refseq": "Lmtk3", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "LOW QUALITY PROTEIN: serine/threonine-protein kinase LMTK3 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:103164350)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030425 dendrite;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K8Y1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K906-1", "uniprot_id": [ { "id": "A0A9J7K906_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K906", "type": "external" } ], "mass": 53650.0, "length": 492, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 3", "gene_name": "LOC100770570", "organism": "Hamster", "refseq_name": "solute carrier family 2, facilitated glucose transporter member 3", "refseq_ac": [ { "id": "XP_027284600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284600", "type": "external" } ], "gene_names_uniprotkb": "LOC100770570", "gene_names_refseq": "LOC100770570", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 3; GLUT-3; Glucose transporter type 3", "protein_names_refseq": "solute carrier family 2, facilitated glucose transporter member 3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770570)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport., [UniProtKB, UniProtKB]; Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033300 dehydroascorbic acid transmembrane transporter activity;GO:0005536 D-glucose binding;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043204 perikaryon;GO:0042995 cell projection", "go_biological_process": "GO:1904659 D-glucose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K906-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9F8-1", "uniprot_id": [ { "id": "A0A9J7K9F8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9F8", "type": "external" } ], "mass": 27469.0, "length": 239, "protein_name": "High mobility group protein B1-like", "gene_name": "LOC113836333", "organism": "Hamster", "refseq_name": "high mobility group protein B1-like", "refseq_ac": [ { "id": "XP_035302946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302946", "type": "external" } ], "gene_names_uniprotkb": "LOC113836333", "gene_names_refseq": "LOC113836333", "protein_names_uniprotkb": "High mobility group protein B1-like", "protein_names_refseq": "high mobility group protein B1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113836333)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; In the cytoplasm proposed to dissociate the BECN1:BCL2 complex via competitive interaction with BECN1 leading to autophagy activation. Can protect BECN1 and ATG5 from calpain-mediated cleavage and thus proposed to control their proautophagic and proapoptotic functions and to regulate the extent and severity of inflammation-associated cellular injury. In myeloid cells has a protective role against endotoxemia and bacterial infection by promoting autophagy. Involved in endosomal translocation and activation of TLR9 in response to CpG-DNA in macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008201 heparin binding;GO:0008289 lipid binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9F8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9G4-1", "uniprot_id": [ { "id": "A0A9J7K9G4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9G4", "type": "external" } ], "mass": 217239.0, "length": 1893, "protein_name": "CD302 antigen", "gene_name": "LOC100769089", "organism": "Hamster", "refseq_name": "lymphocyte antigen 75 isoform X2", "refseq_ac": [ { "id": "XP_035302963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302963", "type": "external" } ], "gene_names_uniprotkb": "LOC100769089", "gene_names_refseq": "LOC100769089", "protein_names_uniprotkb": "CD302 antigen; C-type lectin domain family 13 member A; DEC-205; Lymphocyte antigen 75", "protein_names_refseq": "lymphocyte antigen 75 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100769089)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B lymphocytes., [UniProtKB, UniProtKB]; Multifunctional C-type lectin receptor involved in endocytosis, phagocytosis and regulation of cell adhesion and migration. Plays a critical role in guiding dendritic cells to lymph nodes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030175 filopodium;GO:0005902 microvillus", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9G4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9P7-1", "uniprot_id": [ { "id": "A0A9J7K9P7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9P7", "type": "external" } ], "mass": 195405.0, "length": 1758, "protein_name": "Kinase D-interacting substrate of 220 kDa", "gene_name": "Kidins220", "organism": "Hamster", "refseq_name": "kinase D-interacting substrate of 220 kDa", "refseq_ac": [ { "id": "XP_035303233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303233", "type": "external" } ], "gene_names_uniprotkb": "Kidins220", "gene_names_refseq": "Kidins220", "protein_names_uniprotkb": "Kinase D-interacting substrate of 220 kDa; Ankyrin repeat-rich membrane-spanning protein", "protein_names_refseq": "kinase D-interacting substrate of 220 kDa", "tax_id": 10029, "disease": "", "pathway": " (cge:100768633)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030165 PDZ domain binding;GO:0019887 protein kinase regulator activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0005770 late endosome", "go_biological_process": "GO:0007399 nervous system development;GO:0038180 nerve growth factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9P7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7K9T8-1", "uniprot_id": [ { "id": "A0A9J7K9T8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7K9T8", "type": "external" } ], "mass": 77910.0, "length": 678, "protein_name": "Interleukin-1 receptor accessory protein-like 1", "gene_name": "Il1rapl1", "organism": "Hamster", "refseq_name": "interleukin-1 receptor accessory protein-like 1 isoform X2", "refseq_ac": [ { "id": "XP_035305632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305632", "type": "external" } ], "gene_names_uniprotkb": "Il1rapl1", "gene_names_refseq": "Il1rapl1", "protein_names_uniprotkb": "Interleukin-1 receptor accessory protein-like 1; X-linked interleukin-1 receptor accessory protein-like 1", "protein_names_refseq": "interleukin-1 receptor accessory protein-like 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767870)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0007165 signal transduction;GO:0045920 negative regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7K9T8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAA1-1", "uniprot_id": [ { "id": "A0A9J7KAA1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAA1", "type": "external" } ], "mass": 68486.0, "length": 625, "protein_name": "Transcription factor E4F1", "gene_name": "LOC100773928", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: transcription factor E4F1 isoform X2", "refseq_ac": [ { "id": "XP_035303982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303982", "type": "external" } ], "gene_names_uniprotkb": "LOC100773928", "gene_names_refseq": "LOC100773928", "protein_names_uniprotkb": "Transcription factor E4F1; 2.3.2.27; E4F transcription factor 1; Putative E3 ubiquitin-protein ligase E4F1; RING-type E3 ubiquitin transferase E4F1; Transcription factor E4F; p120E4F", "protein_names_refseq": "LOW QUALITY PROTEIN: transcription factor E4F1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773928)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0010564 regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAB1-1", "uniprot_id": [ { "id": "A0A9J7KAB1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAB1", "type": "external" } ], "mass": 507014.0, "length": 4414, "protein_name": "Dynein axonemal heavy chain 2", "gene_name": "Dnah2", "organism": "Hamster", "refseq_name": "dynein heavy chain 2, axonemal isoform X2", "refseq_ac": [ { "id": "XP_035304013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304013", "type": "external" } ], "gene_names_uniprotkb": "Dnah2", "gene_names_refseq": "Dnah2", "protein_names_uniprotkb": "Dynein axonemal heavy chain 2; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2", "protein_names_refseq": "dynein heavy chain 2, axonemal isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100756503)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As part of the axonemal inner dynein arm complex plays a central role in ciliary beat. Expressed in sperm flagellum, it is required for sperm motility. Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0031514 motile cilium;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAB1-1", "record_type": "protein", "filter_code": "0000000.0000101.000100.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAL6-1", "uniprot_id": [ { "id": "A0A9J7KAL6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAL6", "type": "external" } ], "mass": 108999.0, "length": 986, "protein_name": "Chloride channel protein", "gene_name": "Clcn1", "organism": "Hamster", "refseq_name": "chloride channel protein 1", "refseq_ac": [ { "id": "XP_035306711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306711", "type": "external" } ], "gene_names_uniprotkb": "Clcn1", "gene_names_refseq": "Clcn1", "protein_names_uniprotkb": "Chloride channel protein", "protein_names_refseq": "chloride channel protein 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100751277)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Voltage-gated chloride channel involved in skeletal muscle excitability. Generates most of the plasma membrane chloride conductance in skeletal muscle fibers, stabilizes the resting membrane potential and contributes to the repolarization phase during action potential firing. Forms a homodimeric channel where each subunit has its own ion conduction pathway. Conducts double-barreled currents controlled by two types of gates, two fast glutamate gates that control each subunit independently and a slow common gate that opens and shuts off both subunits simultaneously. Has a significant open probability at muscle resting potential and is further activated upon membrane depolarization. Permeable to small monovalent anions with ion selectivity for chloride > thiocyanate > bromide > nitrate > iodide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" } ], "go_molecular_function": "GO:0005247 voltage-gated chloride channel activity", "go_cellular_component": "GO:0034707 chloride channel complex;GO:0030315 T-tubule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAL6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAM9-1", "uniprot_id": [ { "id": "A0A9J7KAM9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAM9", "type": "external" } ], "mass": 135087.0, "length": 1210, "protein_name": "Multimerin-1", "gene_name": "Mmrn1", "organism": "Hamster", "refseq_name": "multimerin-1 isoform X1", "refseq_ac": [ { "id": "XP_035304341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304341", "type": "external" } ], "gene_names_uniprotkb": "Mmrn1", "gene_names_refseq": "Mmrn1", "protein_names_uniprotkb": "Multimerin-1", "protein_names_refseq": "multimerin-1 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100774475)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:0061045 negative regulation of wound healing;GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:1901731 positive regulation of platelet aggregation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAM9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAQ0-1", "uniprot_id": [ { "id": "A0A9J7KAQ0_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAQ0", "type": "external" } ], "mass": 228164.0, "length": 2035, "protein_name": "F-actin monooxygenase", "gene_name": "Mical3", "organism": "Hamster", "refseq_name": "F-actin-monooxygenase MICAL3 isoform X1", "refseq_ac": [ { "id": "XP_035304410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304410", "type": "external" } ], "gene_names_uniprotkb": "Mical3", "gene_names_refseq": "Mical3", "protein_names_uniprotkb": "F-actin monooxygenase; 1.14.13.225", "protein_names_refseq": "F-actin-monooxygenase MICAL3 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100754319)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.13.225", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.225", "type": "external" }, { "id": "1.6.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.1", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0046872 metal ion binding;GO:0071949 FAD binding;GO:0120501 F-actin monooxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006887 exocytosis;GO:0019417 sulfur oxidation;GO:0030042 actin filament depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAQ1-1", "uniprot_id": [ { "id": "A0A9J7KAQ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAQ1", "type": "external" } ], "mass": 178031.0, "length": 1588, "protein_name": "ATP-binding cassette sub-family C member 8", "gene_name": "Abcc8", "organism": "Hamster", "refseq_name": "ATP-binding cassette sub-family C member 8 isoform X2", "refseq_ac": [ { "id": "XP_035302520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302520", "type": "external" } ], "gene_names_uniprotkb": "Abcc8", "gene_names_refseq": "Abcc8", "protein_names_uniprotkb": "ATP-binding cassette sub-family C member 8; Sulfonylurea receptor 1", "protein_names_refseq": "ATP-binding cassette sub-family C member 8 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100764394)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11; KCNJ11 forms the channel pore while ABCC8 is required for activation and regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0008281 sulfonylurea receptor activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0008282 inward rectifying potassium channel;GO:0042383 sarcolemma", "go_biological_process": "GO:0006813 potassium ion transport;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAV3-1", "uniprot_id": [ { "id": "A0A9J7KAV3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAV3", "type": "external" } ], "mass": 139990.0, "length": 1236, "protein_name": "Receptor-type tyrosine-protein phosphatase O", "gene_name": "Ptpro", "organism": "Hamster", "refseq_name": "receptor-type tyrosine-protein phosphatase O isoform X2", "refseq_ac": [ { "id": "XP_035304608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304608", "type": "external" } ], "gene_names_uniprotkb": "Ptpro", "gene_names_refseq": "Ptpro", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase O; 3.1.3.48; Glomerular epithelial protein 1; Protein tyrosine phosphatase U2", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase O isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100752125)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045296 cadherin binding;GO:0017147 Wnt-protein binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005886 plasma membrane", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0003093 regulation of glomerular filtration;GO:0007411 axon guidance;GO:0072112 podocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAV3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAW6-1", "uniprot_id": [ { "id": "A0A9J7KAW6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAW6", "type": "external" } ], "mass": 14245.0, "length": 129, "protein_name": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)", "gene_name": "LOC103161912", "organism": "Hamster", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase-like", "refseq_ac": [ { "id": "XP_035302945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302945", "type": "external" } ], "gene_names_uniprotkb": "LOC103161912", "gene_names_refseq": "LOC103161912", "protein_names_uniprotkb": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:103161912)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0006915 apoptotic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAW6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAX2-1", "uniprot_id": [ { "id": "A0A9J7KAX2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAX2", "type": "external" } ], "mass": 95933.0, "length": 838, "protein_name": "Dipeptidyl peptidase 4", "gene_name": "Dpp4", "organism": "Hamster", "refseq_name": "dipeptidyl peptidase 4", "refseq_ac": [ { "id": "XP_035302962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302962", "type": "external" } ], "gene_names_uniprotkb": "Dpp4", "gene_names_refseq": "Dpp4", "protein_names_uniprotkb": "Dipeptidyl peptidase 4; 3.4.14.5; Dipeptidyl peptidase IV; T-cell activation antigen CD26", "protein_names_refseq": "dipeptidyl peptidase 4", "tax_id": 10029, "disease": "", "pathway": " (cge:100768361)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 8% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0004177 aminopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045121 membrane raft;GO:0016324 apical plasma membrane;GO:0031258 lamellipodium membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAX2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KAX8-1", "uniprot_id": [ { "id": "A0A9J7KAX8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KAX8", "type": "external" } ], "mass": 58765.0, "length": 538, "protein_name": "Eyes absent homolog", "gene_name": "Eya2", "organism": "Hamster", "refseq_name": "eyes absent homolog 2 isoform X1", "refseq_ac": [ { "id": "XP_035302815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302815", "type": "external" } ], "gene_names_uniprotkb": "Eya2", "gene_names_refseq": "Eya2", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "eyes absent homolog 2 isoform X1", "tax_id": 10029, "disease": "", "pathway": " (cge:100768991)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair;GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KAX8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KB07-1", "uniprot_id": [ { "id": "A0A9J7KB07_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KB07", "type": "external" } ], "mass": 55556.0, "length": 483, "protein_name": "Bile acid receptor", "gene_name": "Nr1h4", "organism": "Hamster", "refseq_name": "bile acid receptor", "refseq_ac": [ { "id": "XP_035307264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307264", "type": "external" } ], "gene_names_uniprotkb": "Nr1h4", "gene_names_refseq": "Nr1h4", "protein_names_uniprotkb": "Bile acid receptor; Farnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14", "protein_names_refseq": "bile acid receptor", "tax_id": 10029, "disease": "", "pathway": " (cge:100763600)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0032052 bile acid binding;GO:0038186 bile acid nuclear receptor activity", "go_cellular_component": "GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0038185 nuclear receptor-mediated bile acid signaling pathway;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KB07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KB10-1", "uniprot_id": [ { "id": "A0A9J7KB10_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KB10", "type": "external" } ], "mass": 135605.0, "length": 1195, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp8b4", "organism": "Hamster", "refseq_name": "probable phospholipid-transporting ATPase IM isoform X2", "refseq_ac": [ { "id": "XP_035302935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302935", "type": "external" } ], "gene_names_uniprotkb": "Atp8b4", "gene_names_refseq": "Atp8b4", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "probable phospholipid-transporting ATPase IM isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759968)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140345 phosphatidylcholine flippase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KB10-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KB29-1", "uniprot_id": [ { "id": "A0A9J7KB29_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KB29", "type": "external" } ], "mass": 117926.0, "length": 1067, "protein_name": "Inactive tyrosine-protein kinase 7", "gene_name": "LOC100774485", "organism": "Hamster", "refseq_name": "inactive tyrosine-protein kinase 7 isoform X2", "refseq_ac": [ { "id": "XP_035307361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307361", "type": "external" } ], "gene_names_uniprotkb": "LOC100774485", "gene_names_refseq": "LOC100774485", "protein_names_uniprotkb": "Inactive tyrosine-protein kinase 7; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7", "protein_names_refseq": "inactive tyrosine-protein kinase 7 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774485)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0030424 axon;GO:0043025 neuronal cell body", "go_biological_process": "GO:0050808 synapse organization;GO:0016055 Wnt signaling pathway;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KB29-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KB33-1", "uniprot_id": [ { "id": "A0A9J7KB33_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KB33", "type": "external" } ], "mass": 44902.0, "length": 400, "protein_name": "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "gene_name": "Cnp", "organism": "Hamster", "refseq_name": "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "refseq_ac": [ { "id": "XP_035303183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303183", "type": "external" } ], "gene_names_uniprotkb": "Cnp", "gene_names_refseq": "Cnp", "protein_names_uniprotkb": "2',3'-cyclic-nucleotide 3'-phosphodiesterase; 3.1.4.37; CNPase; CNP", "protein_names_refseq": "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "tax_id": 10029, "disease": "", "pathway": " (cge:100753220)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.37", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.37", "type": "external" } ], "go_molecular_function": "GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0016020 membrane;GO:0042470 melanosome", "go_biological_process": "GO:0009214 cyclic nucleotide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KB33-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBI6-1", "uniprot_id": [ { "id": "A0A9J7KBI6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBI6", "type": "external" } ], "mass": 222349.0, "length": 1958, "protein_name": "Otoferlin", "gene_name": "Otof", "organism": "Hamster", "refseq_name": "otoferlin", "refseq_ac": [ { "id": "XP_035303518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303518", "type": "external" } ], "gene_names_uniprotkb": "Otof", "gene_names_refseq": "Otof", "protein_names_uniprotkb": "Otoferlin; Fer-1-like protein 2", "protein_names_refseq": "otoferlin", "tax_id": 10029, "disease": "", "pathway": " (cge:100759573)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0035612 AP-2 adaptor complex binding", "go_cellular_component": "GO:0048787 presynaptic active zone membrane;GO:0000139 Golgi membrane;GO:0016323 basolateral plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0016082 synaptic vesicle priming", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBI6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBJ1-1", "uniprot_id": [ { "id": "A0A9J7KBJ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBJ1", "type": "external" } ], "mass": 93945.0, "length": 837, "protein_name": "Histone acetyltransferase", "gene_name": "Kat2a", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: histone acetyltransferase KAT2A isoform X2", "refseq_ac": [ { "id": "XP_035303732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303732", "type": "external" } ], "gene_names_uniprotkb": "Kat2a", "gene_names_refseq": "Kat2a", "protein_names_uniprotkb": "Histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "LOW QUALITY PROTEIN: histone acetyltransferase KAT2A isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100774478)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.3.1.259", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.259", "type": "external" } ], "go_molecular_function": "GO:0043992 histone H3K9 acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0140672 ATAC complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045722 positive regulation of gluconeogenesis;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBN5-1", "uniprot_id": [ { "id": "A0A9J7KBN5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBN5", "type": "external" } ], "mass": 35078.0, "length": 330, "protein_name": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]", "gene_name": "Decr2", "organism": "Hamster", "refseq_name": "peroxisomal 2,4-dienoyl-CoA reductase", "refseq_ac": [ { "id": "XP_003501565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501565", "type": "external" } ], "gene_names_uniprotkb": "Decr2", "gene_names_refseq": "Decr2", "protein_names_uniprotkb": "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; 1.3.1.124; 2,4-dienoyl-CoA reductase 2", "protein_names_refseq": "peroxisomal 2,4-dienoyl-CoA reductase", "tax_id": 10029, "disease": "", "pathway": " (cge:100759323)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003501565.1. COMPLETENESS: full length., [RefSeq]; Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.124", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124", "type": "external" } ], "go_molecular_function": "GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0009062 fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBN5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBQ9-1", "uniprot_id": [ { "id": "A0A9J7KBQ9_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBQ9", "type": "external" } ], "mass": 76618.0, "length": 683, "protein_name": "Myeloperoxidase", "gene_name": "LOC100757792", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: myeloperoxidase-like", "refseq_ac": [ { "id": "XP_035303945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303945", "type": "external" } ], "gene_names_uniprotkb": "LOC100757792", "gene_names_refseq": "LOC100757792", "protein_names_uniprotkb": "Myeloperoxidase; 1.11.2.2", "protein_names_refseq": "LOW QUALITY PROTEIN: myeloperoxidase-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100757792)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels internal stop codons :: corrected 1 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0042742 defense response to bacterium;GO:0042744 hydrogen peroxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBQ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBY1-1", "uniprot_id": [ { "id": "A0A9J7KBY1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBY1", "type": "external" } ], "mass": 223449.0, "length": 1937, "protein_name": "Myosin-6", "gene_name": "LOC100770130", "organism": "Hamster", "refseq_name": "myosin-6 isoform X3", "refseq_ac": [ { "id": "XP_035308409", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308409", "type": "external" } ], "gene_names_uniprotkb": "LOC100770130", "gene_names_refseq": "LOC100770130", "protein_names_uniprotkb": "Myosin-6; Myosin heavy chain 6; Myosin heavy chain, cardiac muscle alpha isoform", "protein_names_refseq": "myosin-6 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100770130)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Muscle contraction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0003012 muscle system process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBY1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KBZ1-1", "uniprot_id": [ { "id": "A0A9J7KBZ1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KBZ1", "type": "external" } ], "mass": 138131.0, "length": 1208, "protein_name": "NACHT, LRR and PYD domains-containing protein 1a isoform X2", "gene_name": "LOC100758136", "organism": "Hamster", "refseq_name": "NACHT, LRR and PYD domains-containing protein 1a isoform X2", "refseq_ac": [ { "id": "XP_035304018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304018", "type": "external" } ], "gene_names_uniprotkb": "LOC100758136", "gene_names_refseq": "LOC100758136", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 1a isoform X2", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 1a isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100758136)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Constitutes the active part of the Nlrp1a inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis., [UniProtKB, UniProtKB]; Constitutes the precursor of the Nlrp1a inflammasome, which mediates autoproteolytic processing within the FIIND domain to generate the N-terminal and C-terminal parts, which are associated non-covalently in absence of pathogens and other damage-associated signals., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0006508 proteolysis;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0042981 regulation of apoptotic process;GO:0012501 programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KBZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KC01-1", "uniprot_id": [ { "id": "A0A9J7KC01_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KC01", "type": "external" } ], "mass": 26645.0, "length": 233, "protein_name": "Somatotropin", "gene_name": "Gh1", "organism": "Hamster", "refseq_name": "somatotropin", "refseq_ac": [ { "id": "XP_035304050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304050", "type": "external" } ], "gene_names_uniprotkb": "Gh1", "gene_names_refseq": "Gh1", "protein_names_uniprotkb": "Somatotropin; Growth hormone", "protein_names_refseq": "somatotropin", "tax_id": 10029, "disease": "", "pathway": " (cge:100770534)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005179 hormone activity;GO:0008083 growth factor activity;GO:0005131 growth hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0031667 response to nutrient levels;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0048513 animal organ development;GO:0060396 growth hormone receptor signaling pathway;GO:0045927 positive regulation of growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KC01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KC06-1", "uniprot_id": [ { "id": "A0A9J7KC06_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KC06", "type": "external" } ], "mass": 66313.0, "length": 580, "protein_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase", "gene_name": "LOC100763224", "organism": "Hamster", "refseq_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform X2", "refseq_ac": [ { "id": "XP_035304065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304065", "type": "external" } ], "gene_names_uniprotkb": "LOC100763224", "gene_names_refseq": "LOC100763224", "protein_names_uniprotkb": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase; 2.4.3.3", "protein_names_refseq": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763224)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 18% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.3", "type": "external" } ], "go_molecular_function": "GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0009312 oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KC06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KC95-1", "uniprot_id": [ { "id": "A0A9J7KC95_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KC95", "type": "external" } ], "mass": 88075.0, "length": 781, "protein_name": "Ribosomal protein S6 kinase", "gene_name": "Rps6ka6", "organism": "Hamster", "refseq_name": "ribosomal protein S6 kinase alpha-6 isoform X3", "refseq_ac": [ { "id": "XP_035306125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306125", "type": "external" } ], "gene_names_uniprotkb": "Rps6ka6", "gene_names_refseq": "Rps6ka6", "protein_names_uniprotkb": "Ribosomal protein S6 kinase; 2.7.11.1", "protein_names_refseq": "ribosomal protein S6 kinase alpha-6 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:100756365)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KC95-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KCC4-1", "uniprot_id": [ { "id": "A0A9J7KCC4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KCC4", "type": "external" } ], "mass": 146792.0, "length": 1310, "protein_name": "Guanine nucleotide exchange factor DBS", "gene_name": "Mcf2l", "organism": "Hamster", "refseq_name": "guanine nucleotide exchange factor DBS isoform X2", "refseq_ac": [ { "id": "XP_035308904", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308904", "type": "external" } ], "gene_names_uniprotkb": "Mcf2l", "gene_names_refseq": "Mcf2l", "protein_names_uniprotkb": "Guanine nucleotide exchange factor DBS; DBL's big sister; MCF2-transforming sequence-like protein", "protein_names_refseq": "guanine nucleotide exchange factor DBS isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100759333)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways. Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0035025 positive regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KCC4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KD04-1", "uniprot_id": [ { "id": "A0A9J7KD04_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KD04", "type": "external" } ], "mass": 55785.0, "length": 505, "protein_name": "Kinesin light chain", "gene_name": "LOC113837287", "organism": "Hamster", "refseq_name": "kinesin light chain 3 isoform X3", "refseq_ac": [ { "id": "XP_027289515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289515", "type": "external" } ], "gene_names_uniprotkb": "LOC113837287; LOC113837894", "gene_names_refseq": "LOC113837894", "protein_names_uniprotkb": "Kinesin light chain", "protein_names_refseq": "kinesin light chain 3 isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:113837894)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277095.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa. May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece., [UniProtKB, UniProtKB]; Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KD04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KD23-1", "uniprot_id": [ { "id": "A0A9J7KD23_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KD23", "type": "external" } ], "mass": 82771.0, "length": 742, "protein_name": "Poly(A) polymerase", "gene_name": "LOC107977018", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: poly(A) polymerase alpha-like isoform X2", "refseq_ac": [ { "id": "XP_035309823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309823", "type": "external" } ], "gene_names_uniprotkb": "LOC107977018", "gene_names_refseq": "LOC107977018", "protein_names_uniprotkb": "Poly(A) polymerase; 2.7.7.19", "protein_names_refseq": "LOW QUALITY PROTEIN: poly(A) polymerase alpha-like isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:107977018)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels internal stop codons :: corrected 2 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277427.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Polymerase that creates the 3'-poly(A) tail of mRNA's., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KD23-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KEM1-1", "uniprot_id": [ { "id": "A0A9J7KEM1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KEM1", "type": "external" } ], "mass": 59808.0, "length": 528, "protein_name": "Steroid 21-hydroxylase", "gene_name": "LOC100767691", "organism": "Hamster", "refseq_name": "steroid 21-hydroxylase isoform X2", "refseq_ac": [ { "id": "XP_035307667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307667", "type": "external" } ], "gene_names_uniprotkb": "LOC100767691", "gene_names_refseq": "LOC100767691", "protein_names_uniprotkb": "Steroid 21-hydroxylase; 1.14.14.16; 21-OHase; Cytochrome P-450c21; Cytochrome P450 21; Cytochrome P450 XXI; Cytochrome P450-C21", "protein_names_refseq": "steroid 21-hydroxylase isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100767691)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.16", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.16", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0005496 steroid binding;GO:0020037 heme binding;GO:0004509 steroid 21-monooxygenase activity;GO:0004508 steroid 17-alpha-monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006705 mineralocorticoid biosynthetic process;GO:0042448 progesterone metabolic process;GO:0042446 hormone biosynthetic process;GO:0006694 steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KEM1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KDN5-1", "uniprot_id": [ { "id": "A0A9J7KDN5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KDN5", "type": "external" } ], "mass": 32630.0, "length": 285, "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "LOC100750585", "organism": "Hamster", "refseq_name": "N-lysine methyltransferase KMT5A-like", "refseq_ac": [ { "id": "XP_035306192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306192", "type": "external" } ], "gene_names_uniprotkb": "LOC100750585", "gene_names_refseq": "LOC100750585", "protein_names_uniprotkb": "N-lysine methyltransferase KMT5A; 2.1.1.361; H4-K20-HMTase KMT5A; Histone-lysine N-methyltransferase KMT5A; Lysine-specific methylase 5A; PR/SET domain-containing protein 07; SET domain-containing protein 8", "protein_names_refseq": "N-lysine methyltransferase KMT5A-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100750585)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response regulation and a positive role in cell migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "3.4.24.71", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.71", "type": "external" } ], "go_molecular_function": "GO:0140944 histone H4K20 monomethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005700 polytene chromosome", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KDN5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KDR1-1", "uniprot_id": [ { "id": "A0A9J7KDR1_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KDR1", "type": "external" } ], "mass": 40759.0, "length": 359, "protein_name": "Type-1 angiotensin II receptor", "gene_name": "Agtr1", "organism": "Hamster", "refseq_name": "type-1 angiotensin II receptor", "refseq_ac": [ { "id": "XP_035307812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307812", "type": "external" } ], "gene_names_uniprotkb": "Agtr1", "gene_names_refseq": "Agtr1", "protein_names_uniprotkb": "Type-1 angiotensin II receptor", "protein_names_refseq": "type-1 angiotensin II receptor", "tax_id": 10029, "disease": "", "pathway": " (cge:100750798)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016493 C-C chemokine receptor activity;GO:0019957 C-C chemokine binding;GO:0001596 angiotensin type I receptor activity;GO:0004945 angiotensin type II receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0019722 calcium-mediated signaling;GO:0019229 regulation of vasoconstriction;GO:0030593 neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KDR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KE27-1", "uniprot_id": [ { "id": "A0A9J7KE27_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KE27", "type": "external" } ], "mass": 126395.0, "length": 1114, "protein_name": "Unconventional myosin-Ia", "gene_name": "Myo1a", "organism": "Hamster", "refseq_name": "unconventional myosin-Ia", "refseq_ac": [ { "id": "XP_035306793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306793", "type": "external" } ], "gene_names_uniprotkb": "Myo1a", "gene_names_refseq": "Myo1a", "protein_names_uniprotkb": "Unconventional myosin-Ia; Brush border myosin I; Myosin I heavy chain", "protein_names_refseq": "unconventional myosin-Ia", "tax_id": 10029, "disease": "", "pathway": " (cge:100752754)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in directing the movement of organelles along actin filaments., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005903 brush border;GO:0005902 microvillus;GO:0016459 myosin complex", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030048 actin filament-based movement;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KE27-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KEI8-1", "uniprot_id": [ { "id": "A0A9J7KEI8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KEI8", "type": "external" } ], "mass": 71883.0, "length": 650, "protein_name": "Steryl-sulfatase", "gene_name": "Arsh", "organism": "Hamster", "refseq_name": "arylsulfatase H isoform X2", "refseq_ac": [ { "id": "XP_035308908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308908", "type": "external" } ], "gene_names_uniprotkb": "Arsh", "gene_names_refseq": "Arsh", "protein_names_uniprotkb": "Steryl-sulfatase; 3.1.6.2; Arylsulfatase C; Steroid sulfatase; Steryl-sulfate sulfohydrolase", "protein_names_refseq": "arylsulfatase H isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100773352)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.6.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity;GO:0004773 steryl-sulfatase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007565 female pregnancy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KEI8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KER6-1", "uniprot_id": [ { "id": "A0A9J7KER6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KER6", "type": "external" } ], "mass": 214479.0, "length": 1956, "protein_name": "Methylcytosine dioxygenase TET", "gene_name": "Tet1", "organism": "Hamster", "refseq_name": "methylcytosine dioxygenase TET1", "refseq_ac": [ { "id": "XP_035307841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307841", "type": "external" } ], "gene_names_uniprotkb": "Tet1", "gene_names_refseq": "Tet1", "protein_names_uniprotkb": "Methylcytosine dioxygenase TET; 1.14.11.80", "protein_names_refseq": "methylcytosine dioxygenase TET1", "tax_id": 10029, "disease": "", "pathway": " (cge:100771765)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.80", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.80", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0070579 DNA 5-methylcytosine dioxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0040029 epigenetic regulation of gene expression;GO:0141166 chromosomal 5-methylcytosine DNA demethylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KER6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KEY3-1", "uniprot_id": [ { "id": "A0A9J7KEY3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KEY3", "type": "external" } ], "mass": 37482.0, "length": 334, "protein_name": "Nucleoporin SEH1", "gene_name": "LOC103159332", "organism": "Hamster", "refseq_name": "nucleoporin SEH1", "refseq_ac": [ { "id": "XP_035309490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309490", "type": "external" } ], "gene_names_uniprotkb": "LOC103159332", "gene_names_refseq": "LOC103159332", "protein_names_uniprotkb": "Nucleoporin SEH1; GATOR2 complex protein SEH1; Nucleoporin seh1; Nup107-160 subcomplex subunit SEH1", "protein_names_refseq": "nucleoporin SEH1", "tax_id": 10029, "disease": "", "pathway": " (cge:103159332)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB]; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0000776 kinetochore;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KEY3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KEY7-1", "uniprot_id": [ { "id": "A0A9J7KEY7_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KEY7", "type": "external" } ], "mass": 42259.0, "length": 393, "protein_name": "Beta-3 adrenergic receptor", "gene_name": "Adrb3", "organism": "Hamster", "refseq_name": "beta-3 adrenergic receptor", "refseq_ac": [ { "id": "XP_035301634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301634", "type": "external" } ], "gene_names_uniprotkb": "Adrb3", "gene_names_refseq": "Adrb3", "protein_names_uniprotkb": "Beta-3 adrenergic receptor; Beta-3 adrenoreceptor", "protein_names_refseq": "beta-3 adrenergic receptor", "tax_id": 10029, "disease": "", "pathway": " (cge:100775030)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613685.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively. The rank order of potency for physiological agonists is norepinephrine > epinephrine. Involved in the regulation of thermogenesis and lipolysis in brown and white adipose tissue, after coupling to G(s) proteins and stimulation of the cAMP-PKA axis. Also activates lipolytic process by coupling to G(i) proteins and consequent initiation of the ERK1/2 MAP kinase cascade. Participates in relaxation of the blood vessels and the urinary bladder. Also mediates negative inotropic effects in cardiomyocytes through activation of an NO synthase pathway and subsequent increase in cGMP levels, possibly involving G(i/o) protein-mediated coupling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051379 epinephrine binding;GO:0015052 beta3-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KEY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KEY8-1", "uniprot_id": [ { "id": "A0A9J7KEY8_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KEY8", "type": "external" } ], "mass": 52226.0, "length": 466, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838323", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_035309522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309522", "type": "external" } ], "gene_names_uniprotkb": "LOC113838323", "gene_names_refseq": "LOC113838323", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838323)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KEY8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KF27-1", "uniprot_id": [ { "id": "A0A9J7KF27_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KF27", "type": "external" } ], "mass": 52594.0, "length": 467, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113839079", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_035309691", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309691", "type": "external" } ], "gene_names_uniprotkb": "LOC113839079", "gene_names_refseq": "LOC113839079", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113839079)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023277029.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KF27-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KF39-1", "uniprot_id": [ { "id": "A0A9J7KF39_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KF39", "type": "external" } ], "mass": 51578.0, "length": 465, "protein_name": "Ras GTPase-activating protein-binding protein 1", "gene_name": "LOC100764418", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: ras GTPase-activating protein-binding protein 1-like", "refseq_ac": [ { "id": "XP_035308312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308312", "type": "external" } ], "gene_names_uniprotkb": "LOC100764418", "gene_names_refseq": "LOC100764418", "protein_names_uniprotkb": "Ras GTPase-activating protein-binding protein 1; 3.6.4.12; 3.6.4.13", "protein_names_refseq": "LOW QUALITY PROTEIN: ras GTPase-activating protein-binding protein 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100764418)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels internal stop codons :: corrected 1 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.8.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.41", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0043204 perikaryon;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KF39-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFE5-1", "uniprot_id": [ { "id": "A0A9J7KFE5_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFE5", "type": "external" } ], "mass": 125000.0, "length": 1111, "protein_name": "Anion exchange protein", "gene_name": "LOC100763623", "organism": "Hamster", "refseq_name": "electrogenic sodium bicarbonate cotransporter 1 isoform X2", "refseq_ac": [ { "id": "XP_035308833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308833", "type": "external" } ], "gene_names_uniprotkb": "LOC100763623", "gene_names_refseq": "LOC100763623", "protein_names_uniprotkb": "Anion exchange protein", "protein_names_refseq": "electrogenic sodium bicarbonate cotransporter 1 isoform X2", "tax_id": 10029, "disease": "", "pathway": " (cge:100763623)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008509 monoatomic anion transmembrane transporter activity;GO:0005452 solute:inorganic anion antiporter activity;GO:0008510 sodium:bicarbonate symporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0051453 regulation of intracellular pH", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFE5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFG6-1", "uniprot_id": [ { "id": "A0A9J7KFG6_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFG6", "type": "external" } ], "mass": 89330.0, "length": 819, "protein_name": "Aconitate hydratase, mitochondrial", "gene_name": "LOC100753154", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: aconitate hydratase, mitochondrial-like", "refseq_ac": [ { "id": "XP_035308810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308810", "type": "external" } ], "gene_names_uniprotkb": "LOC100753154", "gene_names_refseq": "LOC100753154", "protein_names_uniprotkb": "Aconitate hydratase, mitochondrial; 4.2.1.3; Aconitase", "protein_names_refseq": "LOW QUALITY PROTEIN: aconitate hydratase, mitochondrial-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100753154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels internal stop codons :: corrected 1 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006099 tricarboxylic acid cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFH3-1", "uniprot_id": [ { "id": "A0A9J7KFH3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFH3", "type": "external" } ], "mass": 119508.0, "length": 1071, "protein_name": "Atrial natriuretic peptide-converting enzyme", "gene_name": "Corin", "organism": "Hamster", "refseq_name": "atrial natriuretic peptide-converting enzyme isoform X3", "refseq_ac": [ { "id": "XP_035308931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308931", "type": "external" } ], "gene_names_uniprotkb": "Corin", "gene_names_refseq": "Corin", "protein_names_uniprotkb": "Atrial natriuretic peptide-converting enzyme; Corin; Pro-ANP-converting enzyme", "protein_names_refseq": "atrial natriuretic peptide-converting enzyme isoform X3", "tax_id": 10029, "disease": "", "pathway": " (cge:103162946)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide;GO:0016486 peptide hormone processing;GO:0007565 female pregnancy;GO:0035813 regulation of renal sodium excretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFH3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFL2-1", "uniprot_id": [ { "id": "A0A9J7KFL2_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFL2", "type": "external" } ], "mass": 47254.0, "length": 424, "protein_name": "Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase", "gene_name": "LOC100753190", "organism": "Hamster", "refseq_name": "LOW QUALITY PROTEIN: multifunctional protein ADE2-like", "refseq_ac": [ { "id": "XP_035309120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309120", "type": "external" } ], "gene_names_uniprotkb": "LOC100753190", "gene_names_refseq": "LOC100753190", "protein_names_uniprotkb": "Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase; 4.1.1.21; 6.3.2.6", "protein_names_refseq": "LOW QUALITY PROTEIN: multifunctional protein ADE2-like", "tax_id": 10029, "disease": "", "pathway": " (cge:100753190)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.21", "type": "external" }, { "id": "6.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity;GO:0004638 phosphoribosylaminoimidazole carboxylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFQ3-1", "uniprot_id": [ { "id": "A0A9J7KFQ3_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFQ3", "type": "external" } ], "mass": 62983.0, "length": 550, "protein_name": "Interleukin-18 receptor 1", "gene_name": "Il18r1", "organism": "Hamster", "refseq_name": "interleukin-18 receptor 1", "refseq_ac": [ { "id": "XP_035309165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309165", "type": "external" } ], "gene_names_uniprotkb": "Il18r1", "gene_names_refseq": "Il18r1", "protein_names_uniprotkb": "Interleukin-18 receptor 1; CD218 antigen-like family member A; IL1 receptor-related protein; Interleukin-18 receptor alpha", "protein_names_refseq": "interleukin-18 receptor 1", "tax_id": 10029, "disease": "", "pathway": " (cge:100758160)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0042007 interleukin-18 binding;GO:0042008 interleukin-18 receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0032729 positive regulation of type II interferon production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFQ4-1", "uniprot_id": [ { "id": "A0A9J7KFQ4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFQ4", "type": "external" } ], "mass": 163374.0, "length": 1421, "protein_name": "Myosin-11", "gene_name": "LOC100771006", "organism": "Hamster", "refseq_name": "myosin-11", "refseq_ac": [ { "id": "XP_035309303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309303", "type": "external" } ], "gene_names_uniprotkb": "LOC100771006", "gene_names_refseq": "LOC100771006", "protein_names_uniprotkb": "Myosin-11", "protein_names_refseq": "myosin-11", "tax_id": 10029, "disease": "", "pathway": " (cge:100771006)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "29704459;32410221", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0043531 ADP binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0098871 postsynaptic actin cytoskeleton;GO:0005737 cytoplasm;GO:0005903 brush border;GO:0016020 membrane;GO:0016459 myosin complex", "go_biological_process": "GO:0007015 actin filament organization;GO:0031032 actomyosin structure organization;GO:0045184 establishment of protein localization;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A9J7KFQ4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A9J7KFU4-1", "uniprot_id": [ { "id": "A0A9J7KFU4_CRIGR", "url": "https://www.uniprot.org/uniprot/A0A9J7KFU4", "type": "external" } ], "mass": 49497.0, "length": 434, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "LOC113838058", "organism": "Hamster", "refseq_name": "mothers against decapentaplegic homolog 1-like", "refseq_ac": [ { "id": "XP_035309465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309465", "type": "external" } ], "gene_names_uniprotkb": "LOC113838058", "gene_names_refseq": "LOC113838058", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 1-like", "tax_id": 10029, "disease": "", "pathway": " (cge:113838058)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0030509 BMP signaling pathway;GO:0060395 SMAD protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A9J7KFU4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000010000000.0000000000000.000.00000", "kg_view_protein": true } ]