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        ],
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        "gene_name": "SYTL3",
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                "id": "XP_015139696",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139696",
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        "protein_names_refseq": "synaptotagmin-like protein 3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139696.1. COMPLETENESS: full length., [RefSeq]; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions., [UniProtKB, UniProtKB]",
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        "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01038166.1, HAEL01010270.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Oct 28, 2021 this sequence version replaced XP_015131711.2., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0071567 deUFMylase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum",
        "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0006508 proteolysis;GO:1903051 negative regulation of proteolysis involved in protein catabolic process;GO:0033146 regulation of intracellular estrogen receptor signaling pathway;GO:0032649 regulation of type II interferon production",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A8V0XT68-1",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0A8V0XT78",
                "type": "external"
            }
        ],
        "mass": 41952.0,
        "length": 368,
        "protein_name": "G-protein coupled receptor 15",
        "gene_name": "GPR15",
        "organism": "Chicken",
        "refseq_name": "G-protein coupled receptor 15",
        "refseq_ac": [
            {
                "id": "XP_004938269",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938269",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "GPR15",
        "gene_names_refseq": "GPR15",
        "protein_names_uniprotkb": "G-protein coupled receptor 15",
        "protein_names_refseq": "G-protein coupled receptor 15",
        "tax_id": 9031,
        "disease": "",
        "pathway": " (gga:427956);  (R-GGA-418555)",
        "pathway_count": 2,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938269.1. COMPLETENESS: full length., [RefSeq]; G protein-coupled receptor that plays an important role in immune homeostasis. Acts via its natural ligand GPR15LG, a chemokine-like polypeptide strongly expressed in gastrointestinal tissues. GPR15-GPR15LG signaling axis regulates intestinal homeostasis and inflammation through the migration of immune cells. Controls thereby the specific homing of T-cells, particularly FOXP3+ regulatory T-cells (Tregs), to the large intestine lamina propria. Also required for skin localization of thymus-derived dendritic epidermal T-cells. Plays an important role in mediating cytoprotective function as well as angiogenesis of thrombomodulin. Mechanistically, preferentially signals through the Gi/o pathway to inhibit adenylate cyclase activity and activate a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0015026 coreceptor activity;GO:0001618 virus receptor activity",
        "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0001525 angiogenesis;GO:0007186 G protein-coupled receptor signaling pathway;GO:0072678 T cell migration",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8V0XT78-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000100000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8V0XT89-1",
        "uniprot_id": [
            {
                "id": "A0A8V0XT89_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0XT89",
                "type": "external"
            }
        ],
        "mass": 36869.0,
        "length": 333,
        "protein_name": "LRP2-binding protein",
        "gene_name": "LRP2BP",
        "organism": "Chicken",
        "refseq_name": "LRP2-binding protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_040527277",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040527277",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LRP2BP",
        "gene_names_refseq": "LRP2BP",
        "protein_names_uniprotkb": "LRP2-binding protein",
        "protein_names_refseq": "LRP2-binding protein isoform X1",
        "tax_id": 9031,
        "disease": "",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May act as an adapter that regulates LRP2 function., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8V0XT89-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000100000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8V0XTA2-1",
        "uniprot_id": [
            {
                "id": "A0A8V0XTA2_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0XTA2",
                "type": "external"
            }
        ],
        "mass": 42163.0,
        "length": 385,
        "protein_name": "ADP-ribosylhydrolase ARH1",
        "gene_name": "ADPRH",
        "organism": "Chicken",
        "refseq_name": "ADP-ribosylarginine hydrolase isoform 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001265030",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265030",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ADPRH",
        "gene_names_refseq": "ADPRH",
        "protein_names_uniprotkb": "ADP-ribosylhydrolase ARH1; 3.2.2.19; ADP-ribose-L-arginine cleaving enzyme; [Protein ADP-ribosylarginine] hydrolase",
        "protein_names_refseq": "ADP-ribosylarginine hydrolase isoform 1 precursor",
        "tax_id": 9031,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: HAEK01006809.1, HAEL01007302.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992432, SAMN06140853 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000019.1. On Sep 23, 2021 this sequence version replaced NP_001265030.1. Sequence Note:., [RefSeq]; Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003875 ADP-ribosylarginine hydrolase activity;GO:0030955 potassium ion binding;GO:0046872 metal ion binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0051725 protein de-ADP-ribosylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8V0XTA2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000100000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8V0XTA7-1",
        "uniprot_id": [
            {
                "id": "A0A8V0XTA7_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0XTA7",
                "type": "external"
            }
        ],
        "mass": 77925.0,
        "length": 746,
        "protein_name": "GPRIN family member 3",
        "gene_name": "GPRIN3",
        "organism": "Chicken",
        "refseq_name": "G protein-regulated inducer of neurite outgrowth 3",
        "refseq_ac": [
            {
                "id": "XP_015132088",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132088",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "GPRIN3",
        "gene_names_refseq": "GPRIN3",
        "protein_names_uniprotkb": "GPRIN family member 3",
        "protein_names_refseq": "G protein-regulated inducer of neurite outgrowth 3",
        "tax_id": 9031,
        "disease": "",
        "pathway": " (gga:428740)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015132088.1. COMPLETENESS: full length., [RefSeq]; May be involved in neurite outgrowth., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0031175 neuron projection development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8V0XTA7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000100000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8V0XTC1-1",
        "uniprot_id": [
            {
                "id": "A0A8V0XTC1_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0XTC1",
                "type": "external"
            }
        ],
        "mass": 47648.0,
        "length": 428,
        "protein_name": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial",
        "gene_name": "AADAT",
        "organism": "Chicken",
        "refseq_name": "kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_004940979",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940979",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "AADAT",
        "gene_names_refseq": "AADAT",
        "protein_names_uniprotkb": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; 2.6.1.39; 2.6.1.4; 2.6.1.63; 2.6.1.73; 2.6.1.7; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT",
        "protein_names_refseq": "kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1",
        "tax_id": 9031,
        "disease": "",
        "pathway": " (gga:428728);  (R-GGA-71064);  (R-GGA-71240)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940979.1. COMPLETENESS: full length., [RefSeq]; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro)., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.6.1.63",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.63",
                "type": "external"
            },
            {
                "id": "2.6.1.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.39",
                "type": "external"
            },
            {
                "id": "2.6.1.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7",
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            },
            {
                "id": "2.6.1.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.4",
                "type": "external"
            },
            {
                "id": "2.6.1.73",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.73",
                "type": "external"
            },
            {
                "id": "4.4.1.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13",
                "type": "external"
            },
            {
                "id": "2.6.1.64",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.64",
                "type": "external"
            },
            {
                "id": "2.6.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0047315 kynurenine-glyoxylate transaminase activity;GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0047536 2-aminoadipate transaminase activity;GO:0047958 glycine:2-oxoglutarate aminotransferase activity",
        "go_cellular_component": "GO:0005759 mitochondrial matrix",
        "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006536 glutamate metabolic process;GO:0070189 kynurenine metabolic process;GO:1901605 alpha-amino acid metabolic process",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
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            {
                "id": "A0A8V0XTC7_CHICK",
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                "type": "external"
            }
        ],
        "mass": 208270.0,
        "length": 1894,
        "protein_name": "Protein scribble homolog",
        "gene_name": "SCRIB",
        "organism": "Chicken",
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        "gene_names_uniprotkb": "SCRIB",
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        "go_molecular_function": "GO:0019901 protein kinase binding;GO:0035591 signaling adaptor activity",
        "go_cellular_component": "GO:0035748 myelin sheath abaxonal region;GO:0005654 nucleoplasm;GO:0005912 adherens junction;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane",
        "go_biological_process": "GO:0016080 synaptic vesicle targeting;GO:0035089 establishment of apical/basal cell polarity;GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0008283 cell population proliferation;GO:0016477 cell migration",
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            }
        ],
        "mass": 6695.0,
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        "protein_name": "Uncharacterized protein",
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        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
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        "filter_code": "0000000.0000000.100000.000100000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8V0XTC9_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0XTC9",
                "type": "external"
            }
        ],
        "mass": 33335.0,
        "length": 300,
        "protein_name": "Zygote arrest 1-like",
        "gene_name": "ZAR1L",
        "organism": "Chicken",
        "refseq_name": "protein ZAR1-like",
        "refseq_ac": [
            {
                "id": "NP_001165014",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165014",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ZAR1L",
        "gene_names_refseq": "ZAR1L; ZAR1",
        "protein_names_uniprotkb": "Zygote arrest 1-like",
        "protein_names_refseq": "ZAR1-like protein; protein ZAR1-like; zygote arrest 1",
        "tax_id": 9031,
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        "function": "##Evidence-Data-START## Transcript exon combination :: FJ914588.1, BX268835.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On Nov 5, 2021 this sequence version replaced NP_001165014.2., [RefSeq]; mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation. Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003730 mRNA 3'-UTR binding",
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        "kg_view_protein": true
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                "url": "https://www.uniprot.org/uniprot/A0A8V0XTD2",
                "type": "external"
            }
        ],
        "mass": 54543.0,
        "length": 487,
        "protein_name": "Coiled-coil domain containing 97",
        "gene_name": "CCDC97",
        "organism": "Chicken",
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        "refseq_ac": [
            {
                "id": "XP_040511028",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511028",
                "type": "external"
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052569.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Protein LTV1 homolog",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0030688 preribosome, small subunit precursor",
        "go_biological_process": "GO:0000056 ribosomal small subunit export from nucleus;GO:0042274 ribosomal small subunit biogenesis",
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        ],
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        "protein_name": "MTOR-associated protein MEAK7",
        "gene_name": "TLDC1",
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        "gene_names_uniprotkb": "TLDC1",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0005764 lysosome",
        "go_biological_process": "GO:0006979 response to oxidative stress;GO:0042127 regulation of cell population proliferation;GO:0031667 response to nutrient levels;GO:0032868 response to insulin;GO:0030334 regulation of cell migration",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000100000000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
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        "uniprot_canonical_ac": "A0A8V0XTH3-1",
        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0A8V0XTH3",
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            }
        ],
        "mass": 18272.0,
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        "protein_name": "Secretory immunoglobulin A-binding protein EsiB",
        "gene_name": "",
        "organism": "Chicken",
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        "gene_names_uniprotkb": "",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Secretory immunoglobulin A-binding protein EsiB",
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        "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0004674 protein serine/threonine kinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0071622 regulation of granulocyte chemotaxis;GO:0007165 signal transduction;GO:0010976 positive regulation of neuron projection development;GO:0050766 positive regulation of phagocytosis;GO:0010975 regulation of neuron projection development",
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    },
    {
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            {
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        ],
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        "protein_name": "Synapse differentiation inducing 1 like",
        "gene_name": "SYNDIG1L",
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        "refseq_name": "synapse differentiation-inducing gene protein 1-like",
        "refseq_ac": [
            {
                "id": "XP_015143161",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143161",
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            }
        ],
        "gene_names_uniprotkb": "SYNDIG1L",
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        "protein_names_refseq": "synapse differentiation-inducing gene protein 1-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143161.1. COMPLETENESS: full length., [RefSeq]",
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        "pathway": " (R-GGA-1482801);  (R-GGA-1482839)",
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        "protein_name": "Semaphorin 3A",
        "gene_name": "SEMA3A",
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        "gene_names_uniprotkb": "SEMA3A",
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        "protein_names_uniprotkb": "Semaphorin 3A",
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        "pathway": " (R-GGA-399954);  (R-GGA-399955);  (R-GGA-399956)",
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        "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity",
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        "go_biological_process": "GO:0007411 axon guidance;GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0010977 negative regulation of neuron projection development;GO:0001755 neural crest cell migration",
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        ],
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        "tax_id": 9031,
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        "go_molecular_function": "GO:0019781 NEDD8 activating enzyme activity",
        "go_cellular_component": "GO:0070187 shelterin complex;GO:0005637 nuclear inner membrane",
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        ],
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        "length": 769,
        "protein_name": "Glutamate carboxypeptidase 2",
        "gene_name": "FOLH1",
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        "gene_names_uniprotkb": "FOLH1",
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        "protein_names_uniprotkb": "Glutamate carboxypeptidase 2; 3.4.17.21; Folate hydrolase 1; Folylpoly-gamma-glutamate carboxypeptidase; Glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Prostate-specific membrane antigen homolog; Pteroylpoly-gamma-glutamate carboxypeptidase",
        "protein_names_refseq": "",
        "tax_id": 9031,
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        "pathway": " (R-GGA-8963693)",
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        "function": "Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC., [UniProtKB, UniProtKB, UniProtKB]; Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate., [UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Ubiquitin-like-conjugating enzyme ATG10",
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        "gene_names_uniprotkb": "ATG10",
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        "protein_names_uniprotkb": "Ubiquitin-like-conjugating enzyme ATG10; Autophagy-related protein 10",
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        "function": "E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Plays a role in adenovirus-mediated cell lysis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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    },
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        ],
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        "protein_name": "FAM161 centrosomal protein B",
        "gene_name": "FAM161B",
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        "refseq_ac": [
            {
                "id": "XP_040557912",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557912",
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            }
        ],
        "gene_names_uniprotkb": "FAM161B",
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        "protein_names_refseq": "protein FAM161B isoform X1",
        "tax_id": 9031,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 977,
        "protein_name": "Reversion-inducing cysteine-rich protein with Kazal motifs",
        "gene_name": "RECK",
        "organism": "Chicken",
        "refseq_name": "reversion-inducing cysteine-rich protein with Kazal motifs precursor",
        "refseq_ac": [
            {
                "id": "NP_001383455",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383455",
                "type": "external"
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        "gene_names_uniprotkb": "RECK",
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        "protein_names_uniprotkb": "Reversion-inducing cysteine-rich protein with Kazal motifs",
        "protein_names_refseq": "reversion-inducing cysteine-rich protein with Kazal motifs precursor",
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        "pathway": " (gga:420804);  (R-GGA-163125)",
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        "go_biological_process": "GO:1903053 regulation of extracellular matrix organization;GO:0016055 Wnt signaling pathway;GO:0030198 extracellular matrix organization;GO:0030336 negative regulation of cell migration;GO:0001955 blood vessel maturation",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025003406.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "coiled-coil domain-containing protein 191 isoform X1",
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        ],
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        "protein_name": "StAR-related lipid transfer protein 13",
        "gene_name": "STARD13",
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        "refseq_ac": [
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        ],
        "gene_names_uniprotkb": "STARD13",
        "gene_names_refseq": "STARD13",
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        "pathway": " (gga:418908);  (R-GGA-8980692);  (R-GGA-9013026);  (R-GGA-9013106);  (R-GGA-9013148)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938815.1. COMPLETENESS: full length., [RefSeq]",
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            {
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        ],
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        "protein_name": "Glutamate carboxypeptidase 2",
        "gene_name": "NAALAD2",
        "organism": "Chicken",
        "refseq_name": "N-acetylated-alpha-linked acidic dipeptidase 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_040507590",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507590",
                "type": "external"
            }
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        "gene_names_uniprotkb": "NAALAD2",
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        "protein_names_uniprotkb": "Glutamate carboxypeptidase 2; 3.4.17.21; Folate hydrolase 1; Folylpoly-gamma-glutamate carboxypeptidase; Glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Prostate-specific membrane antigen homolog; Pteroylpoly-gamma-glutamate carboxypeptidase",
        "protein_names_refseq": "N-acetylated-alpha-linked acidic dipeptidase 2 isoform X1",
        "tax_id": 9031,
        "disease": "",
        "pathway": " (gga:419010);  (R-GGA-8963693)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC., [UniProtKB, UniProtKB, UniProtKB]; Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity with substrates that have both Pro in the P3' position and Asp or Glu in the P2' position. Lacks carboxypeptidase activity. Lacks dipeptidyl-peptidase IV type activity., [UniProtKB, UniProtKB]; Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate., [UniProtKB, UniProtKB, UniProtKB]",
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        "gene_name": "WWC2",
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        "protein_names_uniprotkb": "WW and C2 domain containing 2",
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        "protein_name": "Hematopoietic lineage cell-specific protein",
        "gene_name": "HCLS1",
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        "protein_names_uniprotkb": "Hematopoietic lineage cell-specific protein; Hematopoietic cell-specific LYN substrate 1; LckBP1",
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        "function": "Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005667 transcription regulator complex",
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        "protein_name": "Transient receptor potential cation channel subfamily C member 6",
        "gene_name": "TRPC6",
        "organism": "Chicken",
        "refseq_name": "short transient receptor potential channel 6 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938897",
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        "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily C member 6",
        "protein_names_refseq": "short transient receptor potential channel 6 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938897.3. COMPLETENESS: full length., [RefSeq]",
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        ],
        "go_molecular_function": "GO:0005262 calcium channel activity;GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0042803 protein homodimerization activity;GO:0015279 store-operated calcium channel activity",
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        "protein_name": "Mesoderm specific transcript",
        "gene_name": "MEST",
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        "function": "Plays an important role in enabling neurons to transition from bipolar to multipolar shapes, a process essential for their correct migration toward the cortical plate during brain development. This function is likely achieved through the regulation of N-cadherin-dependent cell adhesion and the modulation of Akt and canonical Wnt signaling pathways. Essential for the development and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. Negatively regulates the canonical Wnt signaling pathway during adipogenic differentiation by reducing the glycosylation, maturation, and cell membrane localization of the Wnt coreceptor LRP6., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Exosome complex component RRP46",
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        "protein_names_uniprotkb": "Exosome complex component RRP46; Exosome component 5; Ribosomal RNA-processing protein 46",
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        "pathway": " (gga:100858931);  (R-GGA-429958);  (R-GGA-450385);  (R-GGA-6791226);  (R-GGA-9930044)",
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        "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000178 exosome (RNase complex);GO:0005829 cytosol;GO:0000791 euchromatin",
        "go_biological_process": "GO:0006364 rRNA processing;GO:0006401 RNA catabolic process;GO:0071028 nuclear mRNA surveillance;GO:0016075 rRNA catabolic process;GO:0034475 U4 snRNA 3'-end processing",
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        ],
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        "protein_name": "Transcription activation suppressor family member 2",
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        "organism": "Chicken",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414985",
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        ],
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        "protein_name": "Transmembrane protein 123",
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        "gene_names_refseq": "TMEM123",
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        "protein_name": "Beta-1,3-glucosyltransferase",
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        "protein_names_refseq": "beta-1,3-glucosyltransferase isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040509099.1. COMPLETENESS: full length., [RefSeq]; Beta-1,3-glucosyltransferase involved in one of the two pathways responsible for protein O-linked fucosylation, a unique post-translational modification of cysteine-knotted proteins that regulates various biological processes. This pathway targets proteins with Thrombospondin type-1 (TSP1) repeats (TSR) in the endoplasmic reticulum. It starts with POFUT2, which attaches fucose via an O-glycosidic bond to a conserved serine or threonine residue. B3GLCT extends this modification by transferring a glucose molecule from UDP-glucose to the fucose., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Solute carrier family 35 member B4",
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        "function": "##Evidence-Data-START## Transcript exon combination :: AF503351.1, SRR12888526.81231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Sep 23, 2021 this sequence version replaced NP_001009928.1., [RefSeq]",
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        ],
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        "protein_name": "Metabolism of cobalamin associated A",
        "gene_name": "",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5",
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8V0XVG3",
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        ],
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        "length": 524,
        "protein_name": "Cytochrome P450 2U1",
        "gene_name": "CYP2U1",
        "organism": "Chicken",
        "refseq_name": "cytochrome P450 2U1",
        "refseq_ac": [
            {
                "id": "XP_420491",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420491",
                "type": "external"
            }
        ],
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        "protein_names_refseq": "cytochrome P450 2U1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420491.4. COMPLETENESS: full length., [RefSeq]; A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels. Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin., [UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.80",
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0097267 omega-hydroxylase P450 pathway;GO:0006805 xenobiotic metabolic process;GO:0008202 steroid metabolic process;GO:0006082 organic acid metabolic process",
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    },
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            {
                "id": "A0A8V0XVG7_CHICK",
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        ],
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            {
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941077.1. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0032422 purine-rich negative regulatory element binding",
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        "function": "Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex., [UniProtKB, UniProtKB, UniProtKB]",
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        "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase 13; Hotdog-fold thioesterase superfamily member 2; Palmitoyl-CoA hydrolase; Thioesterase superfamily member 2",
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        "function": "Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis., [UniProtKB, UniProtKB]",
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        "protein_names_uniprotkb": "Tyrosyl-DNA phosphodiesterase 2; 5'-tyrosyl-DNA phosphodiesterase",
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        "protein_name": "Interleukin 17 receptor E like",
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        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989818",
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        "pathway": " (gga:395147);  (R-GGA-9833482)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.184834.1, SRR13267649.180154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On Sep 23, 2021 this sequence version replaced NP_989818.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Chicken RPL18 in association with IBD VP3 and PKR affect viral replication., [RefSeq, PubMed]; The Newcastle disease virus-induced translation shutoff at late infection times was attributed to sustaining phosphorylation of eIF2a, which is mediated by continual activation of PKR and degradation of PP1., [RefSeq, PubMed]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139237.1. COMPLETENESS: full length., [RefSeq]",
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            {
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        "pathway": " (gga:431265);  (R-GGA-167044);  (R-GGA-5673001);  (R-GGA-8853659)",
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        "refseq_ac": [
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                "id": "XP_001232940",
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        ],
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        "length": 398,
        "protein_name": "Ethanolaminephosphotransferase 1",
        "gene_name": "SELENOI",
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        "gene_names_uniprotkb": "SELENOI",
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        "protein_names_uniprotkb": "Ethanolaminephosphotransferase 1; 2.7.8.1; Selenoprotein I",
        "protein_names_refseq": "",
        "tax_id": 9031,
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        "function": "Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine (PE) from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway. PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes. The enzyme is critical for the synthesis of several PE species and also catalyzes the synthesis of plasmanyl-PE, a lipid required for proper myelination and neurodevelopment, from 1-alkyl-2-acylglycerol., [UniProtKB, UniProtKB]",
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            {
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            }
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0004307 ethanolaminephosphotransferase activity",
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        "kg_view_protein": true
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        ],
        "mass": 48518.0,
        "length": 428,
        "protein_name": "Uncharacterized protein",
        "gene_name": "C1orf101",
        "organism": "Chicken",
        "refseq_name": "cation channel sperm-associated auxiliary subunit epsilon",
        "refseq_ac": [
            {
                "id": "NP_001376333",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376333",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "C1orf101",
        "gene_names_refseq": "C1orf101; C3H1orf101; CATSPERE",
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        "protein_names_refseq": "cation channel sperm-associated auxiliary subunit epsilon; catsper channel auxiliary subunit epsilon",
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        "function": "##Evidence-Data-START## Transcript exon combination :: ERR2365562.141136.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On Nov 18, 2021 this sequence version replaced NP_001376333.1., [RefSeq]",
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        ],
        "mass": 35126.0,
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        "protein_name": "Ankyrin repeat and SOCS box containing 13",
        "gene_name": "ASB13",
        "organism": "Chicken",
        "refseq_name": "ankyrin repeat and SOCS box protein 13 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_015139598",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139598",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "ASB13",
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        "protein_names_refseq": "ankyrin repeat and SOCS box protein 13 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139598.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Immunoglobulin superfamily member 3",
        "gene_name": "IGSF3",
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        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0045931 positive regulation of mitotic cell cycle;GO:1900034 regulation of cellular response to heat;GO:0000165 MAPK cascade",
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        "protein_name": "Protein AMN1 homolog",
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        "protein_name": "Tubulin folding cofactor B",
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                "url": "https://www.uniprot.org/uniprot/A0A8V0Y1M0",
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            }
        ],
        "mass": 59553.0,
        "length": 530,
        "protein_name": "Lymphocyte cytosolic protein 2",
        "gene_name": "LCP2",
        "organism": "Chicken",
        "refseq_name": "lymphocyte cytosolic protein 2",
        "refseq_ac": [
            {
                "id": "NP_990032",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990032",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LCP2",
        "gene_names_refseq": "LCP2; SLP76",
        "protein_names_uniprotkb": "Lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein",
        "protein_names_refseq": "SLP-76 adaptor protein; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2",
        "tax_id": 9031,
        "disease": "",
        "pathway": " (gga:395438);  (R-GGA-114604);  (R-GGA-202433);  (R-GGA-2424491);  (R-GGA-2871796);  (R-GGA-2871809)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: AF226988.1, HAEK01023572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000256.1. On Sep 23, 2021 this sequence version replaced NP_990032.1., [RefSeq]; Adapter protein primarily involved in signaling pathways within T-cells, as well as other immune cells such as platelets, mast cells, and natural killer (NK) cells. Plays a crucial role for transducing signal from the T-cell receptor (TCR) after antigen recognition leading to T-cell activation. Mechanistically, once phosphorylated by the kinase ZAP70, mediates interactions with the guanine-nucleotide exchange factor VAV1, the adapter protein NCK and the kinase ITK. In turn, stimulates the activation of PKC-theta/PRKCQ and NF-kappa-B transcriptional activity in response to CD3 and CD28 costimulation. Also plays an essential role in AGER-induced signaling pathways including p38 MAPK and ERK1/2 activation leading to cytokine release and pro-inflammatory responses., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005911 cell-cell junction;GO:0044853 plasma membrane raft;GO:0036398 TCR signalosome",
        "go_biological_process": "GO:0002376 immune system process;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0035556 intracellular signal transduction;GO:0050852 T cell receptor signaling pathway;GO:0045576 mast cell activation",
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        ],
        "mass": 29673.0,
        "length": 263,
        "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase",
        "gene_name": "ETFBKMT",
        "organism": "Chicken",
        "refseq_name": "electron transfer flavoprotein beta subunit lysine methyltransferase",
        "refseq_ac": [
            {
                "id": "XP_004937950",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937950",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "ETFBKMT",
        "gene_names_refseq": "ETFBKMT",
        "protein_names_uniprotkb": "Electron transfer flavoprotein beta subunit lysine methyltransferase; ETFB lysine methyltransferase; Protein N-lysine methyltransferase METTL20",
        "protein_names_refseq": "electron transfer flavoprotein beta subunit lysine methyltransferase",
        "tax_id": 9031,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937950.1. COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": [
            {
                "id": "2.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-",
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            },
            {
                "id": "2.1.1.359",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359",
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            },
            {
                "id": "2.1.1.372",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.372",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity;GO:0008168 methyltransferase activity",
        "go_cellular_component": "GO:0005759 mitochondrial matrix",
        "go_biological_process": "GO:1904736 negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0032259 methylation",
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        "record_type": "protein",
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        "kg_view_protein": true
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        "protein_name": "Rho GTPase-activating protein 10",
        "gene_name": "ARHGAP10",
        "organism": "Chicken",
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        "refseq_ac": [],
        "gene_names_uniprotkb": "ARHGAP10",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Rho GTPase-activating protein 10; Rho-type GTPase-activating protein 10",
        "protein_names_refseq": "",
        "tax_id": 9031,
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        "pathway": " (R-GGA-8980692);  (R-GGA-9013148);  (R-GGA-9013149)",
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        "function": "GTPase-activating protein that catalyzes the conversion of active GTP-bound Rho GTPases to their inactive GDP-bound form, thus suppressing various Rho GTPase-mediated cellular processes. Also converts Cdc42 to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death. Associates with MICAL1 on the endosomal membrane to promote Rab8-Rab10-dependent tubule extension. After dissociation with MICAL1, recruits WDR44 which connects the endoplasmic reticulum (ER) with the endosomal tubule, thereby participating in the export of a subset of neosynthesized proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383406",
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        ],
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        "refseq_ac": [
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        "gene_name": "ZFYVE28B",
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "MAX dimerization protein 3",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0031901 early endosome membrane",
        "go_biological_process": "GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway",
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        "filter_code": "0000000.0000000.100000.000100000000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8V0Y456-1",
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            {
                "id": "A0A8V0Y456_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0Y456",
                "type": "external"
            }
        ],
        "mass": 112279.0,
        "length": 961,
        "protein_name": "Coiled-coil domain containing 146",
        "gene_name": "CCDC146",
        "organism": "Chicken",
        "refseq_name": "coiled-coil domain-containing protein 146 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_015131246",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131246",
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            }
        ],
        "gene_names_uniprotkb": "CCDC146",
        "gene_names_refseq": "CCDC146",
        "protein_names_uniprotkb": "Coiled-coil domain containing 146",
        "protein_names_refseq": "coiled-coil domain-containing protein 146 isoform X1",
        "tax_id": 9031,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015131246.1. COMPLETENESS: full length., [RefSeq]",
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        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "",
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        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000100000000000000.0000000000000.000.00000",
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    },
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            {
                "id": "A0A8V0Y4A4_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0Y4A4",
                "type": "external"
            }
        ],
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        "protein_name": "Ras-related protein Rab-24",
        "gene_name": "RAB24",
        "organism": "Chicken",
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        "gene_names_uniprotkb": "RAB24",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Ras-related protein Rab-24; 3.6.5.2",
        "protein_names_refseq": "",
        "tax_id": 9031,
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        "pathway": " (gga:427627)",
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        "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB24 is an atypical RAB protein that presents low GTPase activity and thereby exists predominantly in the GTP-bound active state. RAB24 is required for the clearance of late autophagic vacuoles under basal conditions. It is not needed for starvation-induced autophagy. Involved in the modulation of meiotic apparatus assembly and meiotic progression during oocyte maturation, possibly through regulation of kinetochore-microtubule interaction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
            },
            {
                "id": "3.6.5.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
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            },
            {
                "id": "3.6.5.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3",
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            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
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            }
        ],
        "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity;GO:0003924 GTPase activity",
        "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005819 spindle;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0031410 cytoplasmic vesicle",
        "go_biological_process": "GO:0015031 protein transport;GO:0006914 autophagy;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0001556 oocyte maturation;GO:0140013 meiotic nuclear division",
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        ],
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        "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
        "gene_name": "PSMD8",
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        "gene_names_uniprotkb": "PSMD8",
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        "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit RPN12",
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        "pathway": " (R-GGA-1169091);  (R-GGA-1234176);  (R-GGA-1236978);  (R-GGA-174084);  (R-GGA-174154);  (R-GGA-174178);  (R-GGA-174184);  (R-GGA-187577);  (R-GGA-195253);  (R-GGA-202424);  (R-GGA-2467813);  (R-GGA-2871837);  (R-GGA-349425);  (R-GGA-350562);  (R-GGA-382556);  (R-GGA-450408);  (R-GGA-4608870);  (R-GGA-4641257);  (R-GGA-4641258);  (R-GGA-5358346);  (R-GGA-5607764);  (R-GGA-5610780);  (R-GGA-5610785);  (R-GGA-5632684);  (R-GGA-5658442);  (R-GGA-5668541);  (R-GGA-5687128);  (R-GGA-5689603);  (R-GGA-5689880);  (R-GGA-68867);  (R-GGA-68949);  (R-GGA-69017);  (R-GGA-69601);  (R-GGA-75815);  (R-GGA-8854050);  (R-GGA-8939236);  (R-GGA-8939902);  (R-GGA-8941858);  (R-GGA-8948751);  (R-GGA-8951664);  (R-GGA-9020702);  (R-GGA-9755511);  (R-GGA-9762114);  (R-GGA-9766229);  (R-GGA-983168);  (R-GGA-9907900);  (R-GGA-9929356);  (R-GGA-9929491);  (R-GGA-9931269);  (R-GGA-9932298);  (R-GGA-9954709)",
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        "function": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005838 proteasome regulatory particle;GO:0005634 nucleus;GO:0008541 proteasome regulatory particle, lid subcomplex",
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    },
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        "protein_name": "RNA binding motif protein 43",
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        "gene_names_uniprotkb": "RBM43",
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        "protein_names_uniprotkb": "RNA binding motif protein 43",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139260.1. COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0016020 membrane;GO:0005802 trans-Golgi network",
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                "type": "external"
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        ],
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        "length": 705,
        "protein_name": "Solute carrier family 53 member 1",
        "gene_name": "XPR1",
        "organism": "Chicken",
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        "gene_names_uniprotkb": "XPR1",
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        "protein_names_uniprotkb": "Solute carrier family 53 member 1",
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        "function": "Inorganic ion transporter that mediates phosphate ion export across the plasma membrane. Plays a major role in phosphate homeostasis, preventing intracellular phosphate accumulation and possible calcium phosphate precipitation, ultimately preserving calcium signaling. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7), which are important intracellular signaling molecules involved in regulation of phosphate flux., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0001618 virus receptor activity;GO:0015562 efflux transmembrane transporter activity;GO:0005315 phosphate transmembrane transporter activity;GO:0000822 inositol hexakisphosphate binding",
        "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006817 phosphate ion transport;GO:0016036 cellular response to phosphate starvation;GO:0035435 phosphate ion transmembrane transport;GO:0030643 intracellular phosphate ion homeostasis",
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        "kg_view_protein": true
    },
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        ],
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        "protein_names_uniprotkb": "WT1 interacting protein",
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        "pathway": " (R-GGA-1234176);  (R-GGA-2565942);  (R-GGA-9841922)",
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005912 adherens junction;GO:0000932 P-body;GO:0005667 transcription regulator complex",
        "go_biological_process": "GO:0001666 response to hypoxia;GO:0006355 regulation of DNA-templated transcription;GO:0007010 cytoskeleton organization;GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0035331 negative regulation of hippo signaling",
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            }
        ],
        "mass": 70773.0,
        "length": 626,
        "protein_name": "Ubiquitin-associated and SH3 domain-containing protein A",
        "gene_name": "UBASH3A",
        "organism": "Chicken",
        "refseq_name": "ubiquitin-associated and SH3 domain-containing protein A",
        "refseq_ac": [
            {
                "id": "NP_001308486",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001308486",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "UBASH3A",
        "gene_names_refseq": "UBASH3A",
        "protein_names_uniprotkb": "Ubiquitin-associated and SH3 domain-containing protein A; Suppressor of T-cell receptor signaling 2; T-cell ubiquitin ligand 1",
        "protein_names_refseq": "ubiquitin-associated and SH3 domain-containing protein A",
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        "function": "##Evidence-Data-START## Transcript exon combination :: ERR2365563.119142.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000020.1. On Dec 3, 2021 this sequence version replaced NP_001308486.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck",
        "go_biological_process": "GO:0050860 negative regulation of T cell receptor signaling pathway",
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        ],
        "mass": 26981.0,
        "length": 245,
        "protein_name": "Methyltransferase HEMK2",
        "gene_name": "N6AMT1",
        "organism": "Chicken",
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        "refseq_ac": [],
        "gene_names_uniprotkb": "N6AMT1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Methyltransferase HEMK2; HemK methyltransferase family member 2; Lysine N-methyltransferase 9; Methylarsonite methyltransferase N6AMT1; Methyltransferase N6AMT1; Protein N(5)-glutamine methyltransferase",
        "protein_names_refseq": "",
        "tax_id": 9031,
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        "function": "Methyltransferase that can methylate proteins and, to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. It however only plays a limited role in arsenic metabolism compared with AS3MT., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0036009 protein-glutamine N-methyltransferase activity;GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity;GO:0008276 protein methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035657 eRF1 methyltransferase complex",
        "go_biological_process": "GO:0032259 methylation;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0009404 toxin metabolic process;GO:0045814 negative regulation of gene expression, epigenetic;GO:0018872 arsonoacetate metabolic process",
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        "protein_names_uniprotkb": "Uncharacterized protein",
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        ],
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        ],
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        "protein_name": "Interferon regulatory factor 4",
        "gene_name": "IRF4",
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            {
                "id": "NP_989630",
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        "function": "##Evidence-Data-START## Transcript exon combination :: AF320331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000040.1. On Sep 23, 2021 this sequence version replaced NP_989630.1., [RefSeq]; Show that the transcription factor PU.1 and its functional partner, IRF4, are involved in the expression of activation induced cytidine deaminase gene in chicken B cells., [RefSeq, PubMed]; The avian homolog of the interferon regulatory factor 4 (IRF-4) and a novel splice variant lacking exon 6, IRF-4DeltaE6, were isolated and characterized. Chicken IRF-4 is expressed in lymphoid organs, less in small intestine, and lungs., [RefSeq, PubMed]; The findings support a model where IRF4 expression in addition to BLIMP-1 expression is required to induce robust antibody secretion., [RefSeq, PubMed]; These results reveal that GCN5 is essential for IRF-4 gene expression, followed by transcriptional activation of Blimp-1, and plays a key role in epigenetic regulation of B-cell differentiation., [RefSeq, PubMed]; Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791204",
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            }
        ],
        "gene_names_uniprotkb": "FRRS1L",
        "gene_names_refseq": "FRRS1L",
        "protein_names_uniprotkb": "Ferric chelate reductase 1 like",
        "protein_names_refseq": "DOMON domain-containing protein FRRS1L isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0045505 dynein intermediate chain binding",
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        "go_biological_process": "GO:1900449 regulation of glutamate receptor signaling pathway;GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels",
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    },
    {
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                "id": "A0A8V0Y7F5_CHICK",
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        ],
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        "protein_names_uniprotkb": "Zinc finger CCCH domain-containing protein 4",
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        "pathway": " (R-GGA-9930044)",
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        "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0032785 negative regulation of DNA-templated transcription, elongation;GO:0006351 DNA-templated transcription;GO:0071027 nuclear RNA surveillance;GO:0110064 lncRNA catabolic process",
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        "protein_name": "Embryonic ectoderm development",
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        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0A8V0Y9C5-1",
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            {
                "id": "A0A8V0Y9C5_CHICK",
                "url": "https://www.uniprot.org/uniprot/A0A8V0Y9C5",
                "type": "external"
            }
        ],
        "mass": 70997.0,
        "length": 661,
        "protein_name": "Sodium-dependent multivitamin transporter",
        "gene_name": "SLC5A6",
        "organism": "Chicken",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "SLC5A6",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Sodium-dependent multivitamin transporter; Solute carrier family 5 member 6",
        "protein_names_refseq": "",
        "tax_id": 9031,
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        "pathway": " (R-GGA-196780);  (R-GGA-199220);  (R-GGA-425397)",
        "pathway_count": 3,
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        "function": "Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide. Functions as a Na(+)-coupled substrate symporter where the stoichiometry of Na(+):substrate is 2:1, creating an electrochemical Na(+) gradient used as driving force for substrate uptake. Required for biotin and pantothenate uptake in the intestine across the brush border membrane. Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin. Contributes to the luminal uptake of biotin and pantothenate into the brain across the blood-brain barrier., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0090482 vitamin transmembrane transporter activity;GO:0015293 symporter activity;GO:0015075 monoatomic ion transmembrane transporter activity;GO:0008523 sodium-dependent multivitamin transmembrane transporter activity;GO:0015111 iodide transmembrane transporter activity",
        "go_cellular_component": "GO:0016324 apical plasma membrane",
        "go_biological_process": "GO:0015887 pantothenate transmembrane transport;GO:0006814 sodium ion transport;GO:0015878 biotin transport;GO:0006768 biotin metabolic process;GO:0150104 transport across blood-brain barrier",
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    {
        "uniprot_canonical_ac": "A0A8V0Y632-1",
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        ],
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        "protein_name": "Jumonji domain-containing protein 1C",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051213 dioxygenase activity;GO:0032454 histone H3K9 demethylase activity;GO:0031490 chromatin DNA binding;GO:0003712 transcription coregulator activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000118 histone deacetylase complex",
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        ],
        "mass": 106066.0,
        "length": 1001,
        "protein_name": "Family with sequence similarity 193 member B",
        "gene_name": "FAM193B",
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        "refseq_name": "protein FAM193B isoform X2",
        "refseq_ac": [
            {
                "id": "XP_004944943",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944943",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "FAM193B",
        "gene_names_refseq": "FAM193B",
        "protein_names_uniprotkb": "Family with sequence similarity 193 member B",
        "protein_names_refseq": "protein FAM193B isoform X2",
        "tax_id": 9031,
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        "pathway": " (gga:416216)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI Annotation Status           :: Full annotation Annotation Name             :: Gallus gallus Annotation Release 106 Annotation Version          :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method           :: Best-placed RefSeq; Gnomon Features Annotated          :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944943.2. COMPLETENESS: full length., [RefSeq]",
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