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            }
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                "id": "NP_647890",
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        ],
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            }
        ],
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        "length": 1322,
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        "refseq_name": "Na[+]/H[+] hydrogen exchanger 2, isoform G",
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                "id": "NP_001137851",
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        "protein_names_uniprotkb": "Sodium/hydrogen exchanger",
        "protein_names_refseq": "CG9256-PG; Na[+]/H[+] hydrogen exchanger 2, isoform G; Nhe2-PG; drosophila sodium-proton exchanger 2",
        "tax_id": 7227,
        "disease": "sleep apnea (Disease Ontology:DOID:0050847); left ventricular failure (Disease Ontology:DOID:0051064); congenital secretory sodium diarrhea 8 (Disease Ontology:DOID:0060777); hypertension (Disease Ontology:DOID:10763); exocrine pancreatic insufficiency (Disease Ontology:DOID:13316); malignant renovascular hypertension (Disease Ontology:DOID:13730); cystic fibrosis (Disease Ontology:DOID:1485); renovascular hypertension (Disease Ontology:DOID:1591); nephrolithiasis (Disease Ontology:DOID:585); gastrointestinal system disease (Disease Ontology:DOID:77); end stage renal disease (Disease Ontology:DOID:783); chronic kidney disease (Disease Ontology:DOID:784); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dme:Dmel_CG9256);  (R-DME-425986)",
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                "id": "NP_001247269",
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        "gene_names_uniprotkb": "CG12492; CG13818; lincRNA.840; CG12492; CG13818; CG34355; Dmel\\CG34355; Dmel_CG34355; lincRNA.840",
        "gene_names_refseq": "CG12492; CG13818; CG34355; Dmel\\CG34355; lincRNA.840",
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        "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); stroke (Disease Ontology:DOID:0051061); atypical hemolytic-uremic syndrome (Disease Ontology:DOID:0080301); thrombophilia due to thrombomodulin defect (Disease Ontology:DOID:0111908); brain small vessel disease (Disease Ontology:DOID:0112313); dermatomyositis (Disease Ontology:DOID:10223); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); disseminated intravascular coagulation (Disease Ontology:DOID:11247); adult respiratory distress syndrome (Disease Ontology:DOID:11394); granulomatosis with polyangiitis (Disease Ontology:DOID:12132); familial combined hyperlipidemia (Disease Ontology:DOID:13809); hypothyroidism (Disease Ontology:DOID:1459); impotence (Disease Ontology:DOID:1875); thrombophilia (Disease Ontology:DOID:2452); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); familial Mediterranean fever (Disease Ontology:DOID:2987); acute kidney failure (Disease Ontology:DOID:3021); ischemia (Disease Ontology:DOID:326); coronary artery disease (Disease Ontology:DOID:3393); carotid artery thrombosis (Disease Ontology:DOID:3410); cerebral infarction (Disease Ontology:DOID:3526); lung non-small cell carcinoma (Disease Ontology:DOID:3908); liver disease (Disease Ontology:DOID:409); pulmonary hypertension (Disease Ontology:DOID:6432); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); systemic lupus erythematosus (Disease Ontology:DOID:9074); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)",
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        "gene_names_uniprotkb": "Dmel\\CG5555; CG5555; Dmel_CG5555",
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        "protein_names_uniprotkb": "BRCA1-associated protein; 2.3.2.27; BRAP2; Impedes mitogenic signal propagation; RING-type E3 ubiquitin transferase BRAP2",
        "protein_names_refseq": "CG5555-PB; uncharacterized protein, isoform B",
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        "function": "Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport., [UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            {
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            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
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        ],
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        "go_cellular_component": "GO:0005737 cytoplasm",
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        "protein_name": "Arrestin C-terminal-like domain-containing protein",
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            {
                "id": "NP_001262348",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262348",
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            }
        ],
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        "gene_names_refseq": "CG2993; Dmel\\CG2993",
        "protein_names_uniprotkb": "Arrestin C-terminal-like domain-containing protein",
        "protein_names_refseq": "CG2993-PC; uncharacterized protein, isoform C",
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        "disease": "stomach cancer (Disease Ontology:DOID:10534); Reye syndrome (Disease Ontology:DOID:14525); glaucoma (Disease Ontology:DOID:1686); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)",
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        ],
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        "protein_name": "Serine incorporator, isoform F",
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        "refseq_name": "serine incorporator, isoform F",
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                "id": "NP_001261947",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261947",
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        ],
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        "gene_names_refseq": "CG4672; DmSERINC; Dmel\\CG4672; SERINC; Serinc; TMS1d; TMS1",
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        "go_molecular_function": "GO:0003779 actin binding;GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0048471 perinuclear region of cytoplasm",
        "go_biological_process": "GO:0060439 trachea morphogenesis;GO:0030335 positive regulation of cell migration;GO:0046716 muscle cell cellular homeostasis;GO:0051496 positive regulation of stress fiber assembly;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
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        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000100000000000.0000000001000.001.00000",
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    },
    {
        "uniprot_canonical_ac": "M9ND00-1",
        "uniprot_id": [
            {
                "id": "M9ND00_DROME",
                "url": "https://www.uniprot.org/uniprot/M9ND00",
                "type": "external"
            }
        ],
        "mass": 131719.0,
        "length": 1190,
        "protein_name": "Dynamin associated protein 160, isoform D",
        "gene_name": "Dap160",
        "organism": "Fruit fly",
        "refseq_name": "dynamin associated protein 160, isoform D",
        "refseq_ac": [
            {
                "id": "NP_001246118",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246118",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dap160; CG1099; DAP-160; DAP160; Dmel\\CG1099; Dmel_CG1099; dap160; intersectin; noncoding_4110; p160",
        "gene_names_refseq": "CG1099; DAP-160; DAP160; Dap160/intersectin; Dap160; Dmel\\CG1099; dap160; noncoding_4110; p160",
        "protein_names_uniprotkb": "Dynamin associated protein 160, isoform D",
        "protein_names_refseq": "CG1099-PD; Dap160-PD; Dynamin-associated protein 160 kDa; dynamin associated protein 160, isoform D; dynamin associated protein 160; intersectin",
        "tax_id": 7227,
        "disease": "intellectual disability (Disease Ontology:DOID:1059); nephrotic syndrome (Disease Ontology:DOID:1184)",
        "pathway": " (R-DME-193648);  (R-DME-3928662);  (R-DME-416482);  (R-DME-8856825);  (R-DME-8856828);  (R-DME-9013148);  (R-DME-9013406);  (R-DME-9013420)",
        "pathway_count": 8,
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        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499",
        "class_list": "",
        "function": "",
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        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0030295 protein kinase activator activity;GO:0003676 nucleic acid binding",
        "go_cellular_component": "GO:0008021 synaptic vesicle;GO:0045179 apical cortex;GO:0097708 intracellular vesicle;GO:0005737 cytoplasm;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0048488 synaptic vesicle endocytosis;GO:0016197 endosomal transport;GO:0008104 intracellular protein localization;GO:0045746 negative regulation of Notch signaling pathway;GO:0002052 positive regulation of neuroblast proliferation",
        "synthesized_glycan_count": 0,
        "hit_score": 1.5,
        "record_id": "M9ND00-1",
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        "filter_code": "0000000.0000111.010000.000000100000000000.0100000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "B7Z0D3-1",
        "uniprot_id": [
            {
                "id": "B7Z0D3_DROME",
                "url": "https://www.uniprot.org/uniprot/B7Z0D3",
                "type": "external"
            }
        ],
        "mass": 143600.0,
        "length": 1346,
        "protein_name": "Large proline-rich protein BAG6",
        "gene_name": "clone 2.45",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform D",
        "refseq_ac": [
            {
                "id": "NP_001137904",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137904",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "clone 2.45; CG7546; Dmel\\CG7546; Dmel_CG7546; anon-EST:Liang-2.45",
        "gene_names_refseq": "CG7546; Dmel\\CG7546; anon-EST:Liang-2.45; clone 2.45",
        "protein_names_uniprotkb": "Large proline-rich protein BAG6; BCL2-associated athanogene 6; HLA-B-associated transcript 3",
        "protein_names_refseq": "CG7546-PD; uncharacterized protein, isoform D",
        "tax_id": 7227,
        "disease": "lung non-small cell carcinoma (Disease Ontology:DOID:3908); osteoarthritis (Disease Ontology:DOID:8398); gastrointestinal stromal tumor (Disease Ontology:DOID:9253)",
        "pathway": " (dme:Dmel_CG7546)",
        "pathway_count": 1,
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        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;20146544;25589440;26109356;26109357;28604694;40245499",
        "class_list": "",
        "function": "Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms a complex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53 transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulates histone 3 'Lys-4' dimethylation (H3K4me2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 4,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0031593 polyubiquitin modification-dependent protein binding;GO:0019899 enzyme binding;GO:0051787 misfolded protein binding",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005829 cytosol;GO:0071818 BAT3 complex",
        "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0006325 chromatin organization",
        "synthesized_glycan_count": 0,
        "hit_score": 1.9,
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        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000100000000000.0100000001000.001.00000",
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    },
    {
        "uniprot_canonical_ac": "O46100-1",
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            {
                "id": "O46100_DROME",
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            }
        ],
        "mass": 77859.0,
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        "protein_name": "Solute carrier family 12 member 8",
        "gene_name": "Dmel\\CG12773; EG:8D8.3",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform C",
        "refseq_ac": [
            {
                "id": "NP_001284773",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284773",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG12773; EG:8D8.3; CG12773; Dmel\\CG12773; Dmel_CG12773; EG:8D8.3",
        "gene_names_refseq": "CG12773; Dmel\\CG12773; EG:8D8.3",
        "protein_names_uniprotkb": "Solute carrier family 12 member 8",
        "protein_names_refseq": "CG12773-PC; uncharacterized protein, isoform C",
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        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0006813 potassium ion transport;GO:0003333 amino acid transmembrane transport;GO:0006884 cell volume homeostasis;GO:1902476 chloride transmembrane transport;GO:0055075 potassium ion homeostasis",
        "synthesized_glycan_count": 0,
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    },
    {
        "uniprot_canonical_ac": "X2JGK1-1",
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            {
                "id": "X2JGK1_DROME",
                "url": "https://www.uniprot.org/uniprot/X2JGK1",
                "type": "external"
            }
        ],
        "mass": 140364.0,
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        "protein_name": "Uncharacterized protein",
        "gene_name": "CG18490; CG34240",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform K",
        "refseq_ac": [
            {
                "id": "NP_001287029",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287029",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "CG18490; CG34240; CG18490; CG34240; CG42671; Dmel\\CG42671; Dmel_CG42671",
        "gene_names_refseq": "CG18490; CG34240; CG42671; Dmel\\CG42671",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG42671-PK; uncharacterized protein, isoform K",
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        "pathway": " (dme:Dmel_CG42671)",
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        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II",
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    },
    {
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            {
                "id": "M9PHA0_DROME",
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            }
        ],
        "mass": 139234.0,
        "length": 1305,
        "protein_name": "Bifocal, isoform F",
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        "organism": "Fruit fly",
        "refseq_name": "bifocal, isoform F",
        "refseq_ac": [
            {
                "id": "NP_001259457",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259457",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bif; Bif; CG1822; Dmel\\CG1822; Dmel_CG1822; bif CES",
        "gene_names_refseq": "Bif; CG1822; Dmel\\CG1822; bif CES; bif",
        "protein_names_uniprotkb": "Bifocal, isoform F",
        "protein_names_refseq": "CG1822-PF; bif-PF; bifocal, isoform F; bifocal",
        "tax_id": 7227,
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        "pathway": " (dme:Dmel_CG1822)",
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        "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0030867 rough endoplasmic reticulum membrane",
        "go_biological_process": "GO:0023041 neuronal signal transduction;GO:0007411 axon guidance;GO:0030517 negative regulation of axon extension;GO:0006935 chemotaxis",
        "synthesized_glycan_count": 0,
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        "record_id": "M9PHA0-1",
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        "filter_code": "0000000.0000101.010000.000000100000000000.0000000001000.001.00000",
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    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/M9PEE4",
                "type": "external"
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        ],
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        "protein_name": "SH2 domain-containing adapter protein D",
        "gene_name": "hwt",
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        "refseq_name": "heavyweight, isoform A",
        "refseq_ac": [
            {
                "id": "NP_001259484",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259484",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hwt; 43921; BcDNA:GH02424; CG11146; CG15729; CG32653; CG42251; CG43921; Dmel\\CG43921; Dmel_CG43921; lincRNA.981",
        "gene_names_refseq": "43921; BcDNA:GH02424; CG11146; CG15729; CG32653; CG42251; CG43921; Dmel\\CG43921; hwt; lincRNA.981",
        "protein_names_uniprotkb": "SH2 domain-containing adapter protein D",
        "protein_names_refseq": "CG43921-PA; heavyweight, isoform A; hwt-PA",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG43921)",
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        "class_list": "",
        "function": "May function as an adapter protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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            {
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        "protein_names_refseq": "CG33174-PE; diacylglycerol lipase; inaE-PE; inactivation no afterpotential E, isoform E",
        "tax_id": 7227,
        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); lung cancer (Disease Ontology:DOID:1324); alcohol use disorder (Disease Ontology:DOID:1574); cocaine dependence (Disease Ontology:DOID:9975)",
        "pathway": " (dme:Dmel_CG33174);  (R-DME-426048)",
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        "go_biological_process": "GO:0006816 calcium ion transport;GO:0006813 potassium ion transport;GO:0006814 sodium ion transport;GO:0006874 intracellular calcium ion homeostasis;GO:0070588 calcium ion transmembrane transport",
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        "protein_name": "Guanine nucleotide exchange factor in mesoderm, isoform E",
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        "refseq_name": "guanine nucleotide exchange factor in mesoderm, isoform E",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788403",
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        "gene_names_refseq": "CG18430; CG30115; CG5503; Dmel\\CG30115; GEFmeso",
        "protein_names_uniprotkb": "Guanine nucleotide exchange factor in mesoderm, isoform E",
        "protein_names_refseq": "CG30115-PE; GEFmeso-PE; guanine nucleotide exchange factor in mesoderm, isoform E",
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        "pathway": " (dme:Dmel_CG30115);  (R-DME-193648);  (R-DME-416482);  (R-DME-8980692);  (R-DME-9013148);  (R-DME-9013149);  (R-DME-9013406)",
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        "gene_name": "Dmel\\CG2698",
        "organism": "Fruit fly",
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        "gene_names_refseq": "CG2698; Dmel\\CG2698",
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        "protein_names_refseq": "CG2698-PD; uncharacterized protein, isoform D",
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        "protein_names_refseq": "CG15111-PB; uncharacterized protein, isoform B",
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        ],
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            {
                "id": "NP_732964",
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        "protein_names_refseq": "CG31137-PC; ccr4; twin, isoform C; twin-PC",
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        "protein_names_refseq": "CG42637-PC; uncharacterized protein, isoform C",
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        "protein_name": "TNF-receptor-associated factor 4, isoform A",
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        "refseq_name": "TNF-receptor-associated factor 4, isoform A",
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        "protein_name": "Nuclear fallout, isoform J; Nuclear fallout, isoform K",
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        "organism": "Fruit fly",
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        "protein_names_refseq": "CG33991-PJ; corkscrew interacting Protein-D2; nuclear fallout, isoform J; nuclear fallout; nuclear-fallout; nuf-PJ",
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        "length": 516,
        "protein_name": "Receptor protein serine/threonine kinase put",
        "gene_name": "put",
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        "refseq_name": "punt, isoform B",
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            {
                "id": "NP_001262575",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262575",
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        "gene_names_refseq": "Act-r; Atr-II; Atr88CD; AtrII; Atr; CG7904; Dmel\\CG7904; PUNT; Punt; Put; STK-C; TGF-B; TGF-beta; Tgf-r; atrII; dlhC; l(3)10460; l(3)j5A5; pun; put",
        "protein_names_uniprotkb": "Receptor protein serine/threonine kinase put; 2.7.11.30; Activin type II receptor; Protein punt",
        "protein_names_refseq": "Activin-A-receptor-88CD; CG7904-PB; DPP receptor; TGF-beta-type-receptor-like; activin receptor type II; activin receptor; dorsal holes C; punt, isoform B; punt; put-PB",
        "tax_id": 7227,
        "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); juvenile polyposis syndrome (Disease Ontology:DOID:0050787); visceral heterotaxy 4 (Disease Ontology:DOID:0051019); right atrial isomerism (Disease Ontology:DOID:0060856); pre-eclampsia (Disease Ontology:DOID:10591); Marfan syndrome (Disease Ontology:DOID:14323); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); Lynch syndrome (Disease Ontology:DOID:3883); Weissenbacher-Zweymuller syndrome (Disease Ontology:DOID:4258); cocaine dependence (Disease Ontology:DOID:9975)",
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        "function": "Type II transmembrane receptor serine/threonine kinase involved in activin-like TGF-beta signaling and dpp/BMP-like signaling pathways (PubMed:19766717, PubMed:22563507, PubMed:7697719, PubMed:7697720, PubMed:8289834, PubMed:8415726). Forms a complex with type I transmembrane receptor serine/threonine kinases, and upon activation by signaling ligands induces the type I receptor to phosphorylate downstream receptor-regulated SMAD (R-SMAD) transcription factors, inducing their nuclear localization and resulting in regulation of ligand-responsive genes (PubMed:17119022, PubMed:18820452, PubMed:7697720, PubMed:8289834). Receptor for the activin-like TGF-beta ligands daw and Actbeta/activin when in complex with the type I receptor babo (PubMed:10320478, PubMed:17119022, PubMed:18820452, PubMed:8289834). Activation by daw requires babo isoform C (PubMed:19766717). Receptor for the BMP-like ligand dpp when associated with the type I receptors tkv or sax (PubMed:7697719, PubMed:7697720). Activation by activin-like TGF-beta ligands, including daw and Actbeta/activin, results in phosphorylation of the R-SMAD Smox/SMAD2 (PubMed:10320478, PubMed:17119022, PubMed:18820452, PubMed:19766717, PubMed:8289834). Activation by BMP-like ligands, including gbb and dpp, results in phosphorylation of the R-SMAD Mad (PubMed:18820452, PubMed:19766717). Involved in dpp-signaling-dependent dorsoventral patterning of the epidermis during embryogenesis (PubMed:7697719, PubMed:7697720, PubMed:9504926). Involved in axonal and dendritic pruning and neural remodeling of mushroom body gamma neurons during metamorphosis, probably through regulating expression of the ecdysteroid receptor EcR; functions redundantly with wit (PubMed:12581521). Involved in dpp/BMP-like signaling during development of the embryonic gut tracheal system (PubMed:7697719, PubMed:7697720). Required for dpp/BMP-like signaling involved in imaginal disc development (PubMed:9504926). Involved in differentiation of dorsal cluster and ellipsoid body adult-specific neurons prior to metamorphosis (PubMed:16437159). Required in motoneurons for axon guidance or outgrowth of ISNb and SNa axons (PubMed:17119022). Required in somatic cyst cells for regulation of germ cell proliferation in testis (PubMed:9334286). Involved in adult wing development and wing-vein formation (PubMed:7697720)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]",
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        "go_biological_process": "GO:0006950 response to stress;GO:0048666 neuron development;GO:0007411 axon guidance;GO:0030718 germ-line stem cell population maintenance;GO:0007428 primary branching, open tracheal system",
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        ],
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        "protein_names_refseq": "CG17922-PA; CngB-PA; Cyclic-nucleotide-gated ion channel protein beta-subunit; cyclic nucleotide-gated ion channel subunit B, isoform A",
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        "disease": "achromatopsia 3 (Disease Ontology:DOID:0110008); retinitis pigmentosa 45 (Disease Ontology:DOID:0110402); retinitis pigmentosa (Disease Ontology:DOID:10584); color blindness (Disease Ontology:DOID:13399)",
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        "go_cellular_component": "GO:0017071 intracellular cyclic nucleotide activated cation channel complex;GO:0005886 plasma membrane",
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        "protein_name": "5-hydroxytryptamine (Serotonin) receptor 2B, isoform E",
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                "id": "NP_001262373",
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        "gene_names_refseq": "5-HT-2b; 5-HT2B; 5-HT[[2B]]; 5HT1b; 5HT2B; 5HT2b; CG42796; CG7994; CG8007; Dm5-HT2B; Dm5-HT[[2B]]; Dm5-ht2b; Dmel\\CG42796; anon-WO0170980.94; anon-WO0170980.95; anon-WO0170980.97; anon-WO0170980.98; d5-HT2B",
        "protein_names_uniprotkb": "5-hydroxytryptamine (Serotonin) receptor 2B, isoform E",
        "protein_names_refseq": "5-HT2B-PE; 5-hydroxytryptamine (serotonin) receptor 2B, isoform E; CG42796-PE",
        "tax_id": 7227,
        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); obsessive-compulsive disorder (Disease Ontology:DOID:10933); Prader-Willi syndrome (Disease Ontology:DOID:11983); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); pathological gambling (Disease Ontology:DOID:12399); bladder neck obstruction (Disease Ontology:DOID:13948); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); alcoholic psychosis (Disease Ontology:DOID:252); inflammatory and toxic neuropathy (Disease Ontology:DOID:2537); asthma (Disease Ontology:DOID:2841); substance-related disorder (Disease Ontology:DOID:303); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312); brain infarction (Disease Ontology:DOID:3454); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); heart valve disease (Disease Ontology:DOID:4079); hyperglycemia (Disease Ontology:DOID:4195); pancreatitis (Disease Ontology:DOID:4989); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); acute stress disorder (Disease Ontology:DOID:6088); cocaine abuse (Disease Ontology:DOID:809); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970); cocaine dependence (Disease Ontology:DOID:9975)",
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        "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0008227 G protein-coupled amine receptor activity;GO:0030594 neurotransmitter receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007210 serotonin receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission",
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        "gene_name": "step",
        "organism": "Fruit fly",
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                "id": "NP_001036375",
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        "protein_names_uniprotkb": "Steppke, isoform C; Steppke, isoform D; Steppke, isoform E",
        "protein_names_refseq": "CG11628-PC; general receptor for phosphoinositides 1; general receptor for phosphoinositides-1; lethal (2) SH0323; lethal (2) k08110; step-PC; steppke, isoform C; steppke",
        "tax_id": 7227,
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        "pathway": " (dme:Dmel_CG11628);  (R-DME-6811438)",
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        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032154 cleavage furrow;GO:0005938 cell cortex",
        "go_biological_process": "GO:0030100 regulation of endocytosis;GO:0032956 regulation of actin cytoskeleton organization;GO:0032014 positive regulation of ARF protein signal transduction;GO:0001700 embryonic development via the syncytial blastoderm;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction",
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        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "Dmel\\CG11317",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
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                "id": "NP_001263133",
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        "gene_names_refseq": "CG11317; Dmel\\CG11317",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "CG11317-PB; uncharacterized protein, isoform B",
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                "id": "NP_524699",
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        "gene_names_refseq": "CG3825; Dm-GADD34; Dmel\\CG3825; GADD34; Gadd34; PPP1R15; dGADD34; dPPP1R15; gadd34; ppp1r15",
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        "disease": "stroke (Disease Ontology:DOID:0051061); thalassemia (Disease Ontology:DOID:10241); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316)",
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        "gene_names_refseq": "CG3380; Dmel\\CG3380; EcI-3; OATP58Dc; OATP; Oatp58Dc; oatp 58Dc",
        "protein_names_uniprotkb": "Solute carrier organic anion transporter family member",
        "protein_names_refseq": "CG3380-PB; Oatp58Dc-PB; organic anion transporting polypeptide 58Dc, isoform B; organic anion transporting polypeptide",
        "tax_id": 7227,
        "disease": "prostate cancer (Disease Ontology:DOID:10283); primary biliary cholangitis (Disease Ontology:DOID:12236); Dubin-Johnson syndrome (Disease Ontology:DOID:12308); lung cancer (Disease Ontology:DOID:1324); cholestasis (Disease Ontology:DOID:13580); primary hypertrophic osteoarthropathy (Disease Ontology:DOID:14283); colon carcinoma (Disease Ontology:DOID:1520); colon cancer (Disease Ontology:DOID:219); ovarian cancer (Disease Ontology:DOID:2394); bilirubin metabolic disorder (Disease Ontology:DOID:2741); testicular cancer (Disease Ontology:DOID:2998); breast ductal carcinoma (Disease Ontology:DOID:3007); liver cancer (Disease Ontology:DOID:3571); hepatocellular carcinoma (Disease Ontology:DOID:684); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); steatotic liver disease (Disease Ontology:DOID:9452)",
        "pathway": " (dme:Dmel_CG3380);  (R-DME-6798695);  (R-DME-879518)",
        "pathway_count": 3,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0022857 transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane",
        "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0055085 transmembrane transport;GO:0009636 response to toxic substance;GO:0015711 organic anion transport;GO:0043252 sodium-independent organic anion transport",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W269-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W281-1",
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            {
                "id": "Q9W281_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W281",
                "type": "external"
            }
        ],
        "mass": 74430.0,
        "length": 667,
        "protein_name": "F-box protein 42",
        "gene_name": "Fbxo42",
        "organism": "Fruit fly",
        "refseq_name": "F-box protein 42",
        "refseq_ac": [
            {
                "id": "NP_611647",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611647",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Fbxo42; CG6758; Dmel\\CG6758; Dmel_CG6758; FBXO6",
        "gene_names_refseq": "CG6758; Dmel\\CG6758; FBXO6; Fbxo42",
        "protein_names_uniprotkb": "F-box protein 42",
        "protein_names_refseq": "CG6758-PA; F-box protein 42; Fbxo42-PA",
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        "disease": "",
        "pathway": " (dme:Dmel_CG6758)",
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        "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity",
        "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex",
        "go_biological_process": "GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:1905088 positive regulation of synaptonemal complex assembly",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W298-1",
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            {
                "id": "Q9W298_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W298",
                "type": "external"
            }
        ],
        "mass": 55117.0,
        "length": 478,
        "protein_name": "Sugar phosphate phosphatase",
        "gene_name": "Dmel\\CG2921",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_611635",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611635",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG2921; CG2921; Dmel_CG2921",
        "gene_names_refseq": "CG2921; Dmel\\CG2921",
        "protein_names_uniprotkb": "Sugar phosphate phosphatase; 2.1.1.-; 3.1.3.-",
        "protein_names_refseq": "CG2921-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG2921)",
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        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response., [UniProtKB, UniProtKB, UniProtKB]",
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            {
                "id": "3.1.3.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-",
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            },
            {
                "id": "2.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-",
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            }
        ],
        "go_molecular_function": "GO:0016462 pyrophosphatase activity;GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0051998 protein carboxyl O-methyltransferase activity;GO:0016791 phosphatase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006974 DNA damage response;GO:0032259 methylation;GO:0030643 intracellular phosphate ion homeostasis",
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        "record_id": "Q9W298-1",
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        "uniprot_canonical_ac": "Q9W2A6-1",
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            {
                "id": "Q9W2A6_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W2A6",
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            }
        ],
        "mass": 23265.0,
        "length": 203,
        "protein_name": "GOLD domain-containing protein",
        "gene_name": "Dmel\\CG9308",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_611629",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611629",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG9308; CG9308; Dmel_CG9308; p24",
        "gene_names_refseq": "CG9308; Dmel\\CG9308; p24",
        "protein_names_uniprotkb": "GOLD domain-containing protein",
        "protein_names_refseq": "CG9308-PA; uncharacterized protein",
        "tax_id": 7227,
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        "go_molecular_function": "GO:0038024 cargo receptor activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization;GO:0048193 Golgi vesicle transport",
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            {
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            }
        ],
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        "protein_name": "protein-tyrosine-phosphatase",
        "gene_name": "PTP-ER",
        "organism": "Fruit fly",
        "refseq_name": "protein tyrosine phosphatase-ERK/Enhancer of Ras1",
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            {
                "id": "NP_726092",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726092",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "PTP-ER; CG9856; Dmel\\CG9856; Dmel_CG9856; ER2-5; ptp-er",
        "gene_names_refseq": "CG9856; Dmel\\CG9856; ER2-5; PTP-ER; ptp-er",
        "protein_names_uniprotkb": "protein-tyrosine-phosphatase; 3.1.3.48",
        "protein_names_refseq": "CG9856-PA; PTP-ER-PA; protein tyrosine phosphatase- ERK/enhancer of RAS; protein tyrosine phosphatase-ERK/Enhancer of Ras1",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG9856);  (R-DME-5675221)",
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                "id": "2.7.11.24",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
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        ],
        "go_molecular_function": "GO:0004726 non-membrane spanning protein tyrosine phosphatase activity;GO:0033549 MAP kinase phosphatase activity;GO:0004725 protein tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007165 signal transduction;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0048666 neuron development;GO:0009653 anatomical structure morphogenesis",
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        ],
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        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG10433",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform C",
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            {
                "id": "NP_001286683",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286683",
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            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG10433; CG10433; Dmel_CG10433",
        "gene_names_refseq": "CG10433; Dmel\\CG10433",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG10433-PC; uncharacterized protein, isoform C",
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        "go_cellular_component": "GO:0005615 extracellular space",
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        "protein_names_refseq": "CG3002-PB; Gga-PB; Golgi-localised, gamma-ear containing, ADP ribosylation factor-binding; Golgi-localized, gamma-adaptin ear containing, ARF binding protein",
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        "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); lysosomal storage disease (Disease Ontology:DOID:3211)",
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        "protein_names_uniprotkb": "Brahma associated protein 111kD",
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        "organism": "Fruit fly",
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        "refseq_ac": [
            {
                "id": "NP_001162693",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162693",
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            }
        ],
        "gene_names_uniprotkb": "ND-MNLL; CG15328; CG18624; Dmel\\CG18624; Dmel_CG18624; NDUFB1; NINM; dNDUFB1",
        "gene_names_refseq": "CG15328; CG18624; Dmel\\CG18624; Dromel_CG18624_FBtr0071140_mORF; ND-MNLL; NDUFB1; NINM; dNDUFB1",
        "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; Complex I-MNLL; NADH-ubiquinone oxidoreductase MNLL subunit",
        "protein_names_refseq": "CG18624-PC; NADH dehydrogenase (ubiquinone) MNLL subunit, isoform C; NADH ubiquinone oxidoreductase MNLL; NADH-ubiquinone oxidoreductase MNLL subunit; NADH:ubiquinone oxidoreductase MNLL subunit; ND-MNLL-PC",
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        "pathway": " (dme:Dmel_CG18624);  (R-DME-611105);  (R-DME-6799198)",
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        "class_list": "",
        "function": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I",
        "go_biological_process": "GO:0006120 mitochondrial electron transport, NADH to ubiquinone;GO:1902600 proton transmembrane transport",
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    },
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        "protein_name": "Rab39, isoform A; Rab39, isoform B",
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            {
                "id": "NP_001245568",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245568",
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        ],
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        "disease": "syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); Waisman syndrome (Disease Ontology:DOID:0111781); non-syndromic X-linked intellectual disability 72 (Disease Ontology:DOID:0112059)",
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            {
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            {
                "id": "NP_572379",
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        ],
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        "protein_name": "Fibronectin type III domain-containing protein",
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                "id": "NP_001036262",
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                "id": "BOUD_DROME",
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        ],
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        "protein_name": "UPAR/Ly6 domain-containing protein bou",
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        "organism": "Fruit fly",
        "refseq_name": "boudin",
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            {
                "id": "NP_572373",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572373",
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        ],
        "gene_names_uniprotkb": "bou; CG14430; JNXL4; jnL4",
        "gene_names_refseq": "BcDNA:RE28342; CG14430; Dmel\\CG14430; JNXL4; bou; jnL4; l(1)6Ea; l(1)jnL4",
        "protein_names_uniprotkb": "UPAR/Ly6 domain-containing protein bou; Protein boudin",
        "protein_names_refseq": "CG14430-PA; bou-PA; boudin; lethal (1) 6Ea",
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        "function": "Involved in tracheal paracellular barrier functions mediated by epithelial cell septate junctions (PubMed:19502482). Involved in paracellular barrier functions mediated by glial cell septate junctions in the peripheral nervous system, including the chordotonal organs, but not the hemolymph-brain barrier (the insect blood-brain barrier) of the central nervous system (PubMed:19502482). Required for septate junction assembly, possibly by organizing the preassembly and transport of septate junction proteins such as dlg1/disks large 1, Nrx-IV/Neurexin-IV and the claudin protein kune (PubMed:19502482, PubMed:28977027). Involved in chitin fiber organization during tracheal development (PubMed:19502482). Secreted, possibly in association with extracellular vesicles, to act non-autonomously on tissues distant from its site of expression (PubMed:19502482, PubMed:28977027)., [UniProtKB, PubMed, PubMed]",
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        "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0016327 apicolateral plasma membrane;GO:0005918 septate junction",
        "go_biological_process": "GO:0030431 sleep;GO:0032222 regulation of synaptic transmission, cholinergic;GO:0035152 regulation of tube architecture, open tracheal system;GO:0019991 septate junction assembly",
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        "protein_name": "Acyl-coenzyme A oxidase",
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        ],
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        "gene_names_refseq": "CG4586; Dmel\\CG4586",
        "protein_names_uniprotkb": "Acyl-coenzyme A oxidase",
        "protein_names_refseq": "CG4586-PA; acyl-coenzyme A oxidase; uncharacterized protein",
        "tax_id": 7227,
        "disease": "peroxisomal acyl-CoA oxidase deficiency (Disease Ontology:DOID:0050797); Mitchell syndrome (Disease Ontology:DOID:0070516); congenital bile acid synthesis defect 6 (Disease Ontology:DOID:0111067); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dme:Dmel_CG4586);  (R-DME-193368);  (R-DME-389887);  (R-DME-9033241)",
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        "publication_count": 11,
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        "go_molecular_function": "GO:0005504 fatty acid binding;GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0003997 acyl-CoA oxidase activity",
        "go_cellular_component": "GO:0005777 peroxisome",
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        "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); leprosy (Disease Ontology:DOID:1024); asbestosis (Disease Ontology:DOID:10320); silicosis (Disease Ontology:DOID:10325); hypertension (Disease Ontology:DOID:10763); sarcoidosis (Disease Ontology:DOID:11335); allergic disease (Disease Ontology:DOID:1205); aspergillosis (Disease Ontology:DOID:13564); cystic fibrosis (Disease Ontology:DOID:1485); candidiasis (Disease Ontology:DOID:1508); Gaucher's disease (Disease Ontology:DOID:1926); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); pulmonary fibrosis (Disease Ontology:DOID:3770); tuberculosis (Disease Ontology:DOID:399); allergic rhinitis (Disease Ontology:DOID:4481); neuromyelitis optica (Disease Ontology:DOID:8869); intrinsic asthma (Disease Ontology:DOID:9360); allergic asthma (Disease Ontology:DOID:9415); bronchiectasis (Disease Ontology:DOID:9563)",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9",
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                "id": "3.4.24.-",
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        ],
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                "id": "NP_572332",
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        ],
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        "protein_names_refseq": "CG3226-PA; uncharacterized protein",
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        "disease": "pancreatic cancer (Disease Ontology:DOID:1793); myocardial infarction (Disease Ontology:DOID:5844)",
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        "function": "May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1)., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
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        ],
        "gene_names_uniprotkb": "Dmel\\CG3823; CG3823; Dmel_CG3823",
        "gene_names_refseq": "CG3823; Dmel\\CG3823",
        "protein_names_uniprotkb": "CRAL-TRIO domain-containing protein",
        "protein_names_refseq": "CG3823-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG3823);  (R-DME-8877627)",
        "pathway_count": 2,
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        "class_list": "",
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        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding",
        "go_cellular_component": "GO:0005770 late endosome",
        "go_biological_process": "GO:0120009 intermembrane lipid transfer",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W408-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W410-1",
        "uniprot_id": [
            {
                "id": "Q9W410_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W410",
                "type": "external"
            }
        ],
        "mass": 98336.0,
        "length": 878,
        "protein_name": "PHD finger protein 12",
        "gene_name": "PF1",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_572311",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572311",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "PF1; CG3815; Dmel\\CG3815; Dmel_CG3815; Pf1",
        "gene_names_refseq": "CG3815; Dmel\\CG3815; PF1; Pf1",
        "protein_names_uniprotkb": "PHD finger protein 12; PHD factor 1",
        "protein_names_refseq": "CG3815-PA; PF1; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG3815)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "Q8T0U1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0070822 Sin3-type complex",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W410-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W424-1",
        "uniprot_id": [
            {
                "id": "Q9W424_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W424",
                "type": "external"
            }
        ],
        "mass": 37829.0,
        "length": 347,
        "protein_name": "Splicing factor 3B subunit 4",
        "gene_name": "Spx",
        "organism": "Fruit fly",
        "refseq_name": "spliceosomal protein on the X",
        "refseq_ac": [
            {
                "id": "NP_511058",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_511058",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Spx; CG3780; Dmel\\CG3780; Dmel_CG3780; SF3B4; SPX; spx",
        "gene_names_refseq": "CG3780; Dmel\\CG3780; SF3B4; SPX; Spx; spx",
        "protein_names_uniprotkb": "Splicing factor 3B subunit 4",
        "protein_names_refseq": "CG3780-PA; Spx-PA; spliceosomal protein on the X",
        "tax_id": 7227,
        "disease": "pancreatic cancer (Disease Ontology:DOID:1793); cervical cancer (Disease Ontology:DOID:4362); Nager acrofacial dysostosis (Disease Ontology:DOID:5768); hepatocellular carcinoma (Disease Ontology:DOID:684)",
        "pathway": " (dme:Dmel_CG3780);  (R-DME-72163);  (R-DME-72165);  (R-DME-9770562);  (R-DME-9943411)",
        "pathway_count": 5,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding",
        "go_cellular_component": "GO:0005686 U2 snRNP;GO:0071011 precatalytic spliceosome",
        "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W424-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W455-1",
        "uniprot_id": [
            {
                "id": "Q9W455_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W455",
                "type": "external"
            }
        ],
        "mass": 54507.0,
        "length": 477,
        "protein_name": "Uncharacterized protein",
        "gene_name": "XRCC4",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001284918",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284918",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "XRCC4; CG12728; Dmel\\CG12728; Dmel_CG12728; XLF1",
        "gene_names_refseq": "CG12728; Dmel\\CG12728; XLF1; XRCC4",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG12728-PB; X-ray repair cross-complementing protein 4; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "severe combined immunodeficiency 124 (Disease Ontology:DOID:0061090)",
        "pathway": " (dme:Dmel_CG12728)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W455-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W457-1",
        "uniprot_id": [
            {
                "id": "Q9W457_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W457",
                "type": "external"
            }
        ],
        "mass": 58801.0,
        "length": 537,
        "protein_name": "Serine hydroxymethyltransferase",
        "gene_name": "Shmt",
        "organism": "Fruit fly",
        "refseq_name": "serine hydroxymethyl transferase, isoform A",
        "refseq_ac": [
            {
                "id": "NP_572278",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572278",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Shmt; 144561_at; CG3011; Dmel\\CG3011; Dmel_CG3011; HTMLA; Q9W457; SHMT; Shmt2; anon-WO03040301.100; shmt",
        "gene_names_refseq": "144561_at; CG3011; Dmel\\CG3011; HTMLA; Q9W457; SHMT; Shmt2; Shmt; anon-WO03040301.100; shmt",
        "protein_names_uniprotkb": "Serine hydroxymethyltransferase; 2.1.2.1",
        "protein_names_refseq": "CG3011-PA; Shmt-PA; beta-hydroxy-Epsilon-N-trimethyllysine aldolase; glycine hydroxylmethyltransferase; serine hydroxymethyl transferase 2; serine hydroxymethyl transferase, isoform A; serine hydroxymethyltransferase 2",
        "tax_id": 7227,
        "disease": "neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities (Disease Ontology:DOID:0070543); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); ovarian cancer (Disease Ontology:DOID:2394); schizophrenia (Disease Ontology:DOID:5419); amino acid metabolic disorder (Disease Ontology:DOID:9252)",
        "pathway": " (dme:Dmel_CG3011);  (R-DME-196757);  (R-DME-71262)",
        "pathway_count": 3,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Interconversion of serine and glycine., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
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        "reported_phosphosites": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 7,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.1.2.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004372 glycine hydroxymethyltransferase activity;GO:0120567 hydroxytrimethyllysine aldolase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix",
        "go_biological_process": "GO:0048149 behavioral response to ethanol;GO:0042752 regulation of circadian rhythm;GO:0035999 tetrahydrofolate interconversion;GO:0046653 tetrahydrofolate metabolic process;GO:0019264 glycine biosynthetic process from serine",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W457-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W459-1",
        "uniprot_id": [
            {
                "id": "Q9W459_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W459",
                "type": "external"
            }
        ],
        "mass": 56285.0,
        "length": 494,
        "protein_name": "Fatty acyl-CoA reductase",
        "gene_name": "Dmel\\CG4020",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001259264",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259264",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG4020; CG4020; Dmel_CG4020",
        "gene_names_refseq": "CG4020; Dmel\\CG4020",
        "protein_names_uniprotkb": "Fatty acyl-CoA reductase; 1.2.1.84",
        "protein_names_refseq": "CG4020-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG4020);  (R-DME-9640463)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Catalyzes the reduction of fatty acyl-CoA to fatty alcohols., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.2.1.84",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.84",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity;GO:0102965 alcohol-forming long-chain fatty acyl-CoA reductase activity",
        "go_cellular_component": "GO:0005777 peroxisome;GO:0016020 membrane",
        "go_biological_process": "GO:0035336 long-chain fatty-acyl-CoA metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9W459-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9W470-1",
        "uniprot_id": [
            {
                "id": "Q9W470_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9W470",
                "type": "external"
            }
        ],
        "mass": 33000.0,
        "length": 307,
        "protein_name": "Proteasome subunit beta",
        "gene_name": "Prosbeta2R1",
        "organism": "Fruit fly",
        "refseq_name": "proteasome beta2 subunit-related 1",
        "refseq_ac": [
            {
                "id": "NP_572267",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572267",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Prosbeta2R1; CG18341; Dmel\\CG18341; Dmel_CG18341; beta2R1",
        "gene_names_refseq": "CG18341; Dmel\\CG18341; Prosbeta2R1; beta2R1",
        "protein_names_uniprotkb": "Proteasome subunit beta",
        "protein_names_refseq": "CG18341-PA; Prosbeta2R1-PA; proteasome beta2 subunit-related 1; proteasome beta2R1 subunit",
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        "disease": "Omenn syndrome (Disease Ontology:DOID:0060010)",
        "pathway": " (dme:Dmel_CG18341);  (R-DME-1236974);  (R-DME-1236978);  (R-DME-9907900);  (R-DME-9912633)",
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        "function": "Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB, UniProtKB]; Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005829 cytosol",
        "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process",
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            {
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                "id": "NP_001162664",
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        "function": "Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals., [UniProtKB, UniProtKB]",
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        "protein_name": "DUF4777 domain-containing protein",
        "gene_name": "Dmel\\CG12691",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572157",
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            {
                "id": "Q9XZ29_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9XZ29",
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            }
        ],
        "mass": 135813.0,
        "length": 1212,
        "protein_name": "5.6.1.3; Kinesin-like protein at 3A, isoform A; Kinesin-like protein at 3A, isoform B",
        "gene_name": "Klp3A",
        "organism": "Fruit fly",
        "refseq_name": "Kinesin-like protein at 3A, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001284830",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284830",
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            }
        ],
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        "gene_names_refseq": "3A7Kin; BcDNA:LD21815; CG8590; DmKLP3A; DmKlp3A; Dmel\\CG8590; EG:BACR25B3.9; KIF 4A; KIF4A; KIF4; KLP-3A; KLP3A; Klp 3A; Klp3A; Klp3a; fs(1)M4; klp3A; klp3a; mei-352",
        "protein_names_uniprotkb": "5.6.1.3; Kinesin-like protein at 3A, isoform A; Kinesin-like protein at 3A, isoform B",
        "protein_names_refseq": "CG8590-PB; Kinesin-Like-Protein-at-3A; Kinesin-like protein at 3A, isoform B; Kinesin5; Klp3A-PB; female sterile(1)M4; meiotic 352",
        "tax_id": 7227,
        "disease": "non-syndromic X-linked intellectual disability 100 (Disease Ontology:DOID:0112040); epilepsy (Disease Ontology:DOID:1826)",
        "pathway": " (dme:Dmel_CG8590);  (R-DME-983189)",
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            {
                "id": "5.6.1.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.3",
                "type": "external"
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        ],
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005829 cytosol;GO:0005874 microtubule",
        "go_biological_process": "GO:0016321 female meiosis chromosome segregation;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0007338 single fertilization;GO:0007018 microtubule-based movement",
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        "uniprot_canonical_ac": "Q9Y134-1",
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            {
                "id": "Q9Y134_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9Y134",
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            }
        ],
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        "length": 1055,
        "protein_name": "RNA helicase",
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        "refseq_name": "Mtr4 helicase",
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            {
                "id": "NP_524929",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524929",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Mtr4; BG:DS09217.2; BcDNA:GH07290; CG4152; Dmel\\CG4152; Dmel_CG4152; L(2)35Df; br44; cg4152; dMtr4; l(2)35Df; l(2)br44; l(2)k14422; l(2)k14423; l.2.35Df; lethal(2)35Df",
        "gene_names_refseq": "BG:DS09217.2; BcDNA:GH07290; CG4152; Dmel\\CG4152; L(2)35Df; Mtr4; br44; cg4152; dMtr4; l(2)35Df; l(2)br44; l(2)k14422; l(2)k14423; l.2.35Df; lethal(2)35Df",
        "protein_names_uniprotkb": "RNA helicase; 3.6.4.13",
        "protein_names_refseq": "CG4152-PA; Mtr4 helicase; Mtr4-PA; lethal (2) 35Df",
        "tax_id": 7227,
        "disease": "amyotrophic lateral sclerosis (Disease Ontology:DOID:332)",
        "pathway": " (dme:Dmel_CG4152);  (R-DME-6791226);  (R-DME-72163);  (R-DME-9930044)",
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            {
                "id": "2.7.7.19",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19",
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            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
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            {
                "id": "2.7.7.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6",
                "type": "external"
            },
            {
                "id": "5.2.1.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8",
                "type": "external"
            },
            {
                "id": "3.1.13.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.-",
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            },
            {
                "id": "2.1.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-",
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            }
        ],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity",
        "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome;GO:0031499 TRAMP complex",
        "go_biological_process": "GO:0051607 defense response to virus;GO:0000398 mRNA splicing, via spliceosome;GO:0000460 maturation of 5.8S rRNA;GO:0006401 RNA catabolic process",
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                "id": "Q9Y153_DROME",
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            }
        ],
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        "protein_name": "Uncharacterized protein",
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            {
                "id": "NP_608619",
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        ],
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        "protein_names_refseq": "CG17712-PA; uncharacterized protein",
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    {
        "uniprot_canonical_ac": "Q9Y156-1",
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            {
                "id": "Q9Y156_DROME",
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        "length": 337,
        "protein_name": "Obstructor-B",
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        "organism": "Fruit fly",
        "refseq_name": "obstructor-B",
        "refseq_ac": [
            {
                "id": "NP_609339",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609339",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "obst-B; BEST:CK00178; BcDNA:GH02976; CG4778; CK00178; Dmel\\CG4778; Dmel_CG4778; obst-b",
        "gene_names_refseq": "BEST:CK00178; BcDNA:GH02976; CG4778; CK00178; Dmel\\CG4778; obst-B; obst-b",
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        "protein_names_refseq": "CG4778-PA; obst-B-PA; obstructor-B",
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        "go_molecular_function": "GO:0008061 chitin binding;GO:0005214 structural constituent of chitin-based cuticle",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0062129 chitin-based extracellular matrix;GO:0030312 external encapsulating structure",
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                "id": "Q9Y166_DROME",
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                "type": "external"
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        ],
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        "length": 280,
        "protein_name": "Dicarboxylate carrier 1, isoform A; Dicarboxylate carrier 1, isoform B; Dicarboxylate carrier 1, isoform C",
        "gene_name": "Dic1",
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        "refseq_name": "dicarboxylate carrier 1, isoform C",
        "refseq_ac": [
            {
                "id": "NP_001287313",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287313",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "Dic1; BcDNA:GH02431; CG8790; DmDic1p; Dmel\\CG8790; Dmel_CG8790",
        "gene_names_refseq": "BcDNA:GH02431; CG8790; Dic1; DmDic1p; Dmel\\CG8790",
        "protein_names_uniprotkb": "Dicarboxylate carrier 1, isoform A; Dicarboxylate carrier 1, isoform B; Dicarboxylate carrier 1, isoform C",
        "protein_names_refseq": "CG8790-PC; Dic1-PC; dicarboxylate carrier 1, isoform C",
        "tax_id": 7227,
        "disease": "myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); mitochondrial complex I deficiency (Disease Ontology:DOID:0060536); mitochondrial DNA depletion syndrome (Disease Ontology:DOID:0070329); mitochondrial DNA depletion syndrome 19 (Disease Ontology:DOID:0070450)",
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        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0006094 gluconeogenesis;GO:1902358 sulfate transmembrane transport;GO:0015709 thiosulfate transport;GO:0015729 oxaloacetate transport;GO:0035435 phosphate ion transmembrane transport",
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        "refseq_name": "uncharacterized protein, isoform C",
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                "id": "NP_001245901",
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        "gene_names_refseq": "CG43185; Dmel\\CG43185",
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        "protein_names_refseq": "CG43185-PC; uncharacterized protein, isoform C",
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        "disease": "orofacial cleft (Disease Ontology:DOID:0050567); inflammatory bowel disease (Disease Ontology:DOID:0050589); alcohol dependence (Disease Ontology:DOID:0050741); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); medulloblastoma (Disease Ontology:DOID:0050902); myelodysplastic syndrome (Disease Ontology:DOID:0050908); pre-malignant neoplasm (Disease Ontology:DOID:0060071); acute promyelocytic leukemia (Disease Ontology:DOID:0060318); drug allergy (Disease Ontology:DOID:0060500); alcohol-associated liver disease (Disease Ontology:DOID:0070658); mucositis (Disease Ontology:DOID:0080178); colorectal carcinoma (Disease Ontology:DOID:0080199); COVID-19 (Disease Ontology:DOID:0080600); venous insufficiency (Disease Ontology:DOID:10128); osteonecrosis (Disease Ontology:DOID:10159); prostate cancer (Disease Ontology:DOID:10283); lymphoid leukemia (Disease Ontology:DOID:1037); Hirschsprung's disease (Disease Ontology:DOID:10487); stomach cancer (Disease Ontology:DOID:10534); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); Alzheimer's disease (Disease Ontology:DOID:10652); primary open angle glaucoma (Disease Ontology:DOID:1070); hypertension (Disease Ontology:DOID:10763); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); hypospadias (Disease Ontology:DOID:10892); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); head and neck cancer (Disease Ontology:DOID:11934); optic neuritis (Disease Ontology:DOID:1210); beta thalassemia (Disease Ontology:DOID:12241); neutropenia (Disease Ontology:DOID:1227); aplastic anemia (Disease Ontology:DOID:12449); cardiovascular system disease (Disease Ontology:DOID:1287); lung cancer (Disease Ontology:DOID:1324); Fanconi anemia (Disease Ontology:DOID:13636); exfoliation syndrome (Disease Ontology:DOID:13641); Parkinson's disease (Disease Ontology:DOID:14330); aggressive periodontitis (Disease Ontology:DOID:1474); cystic fibrosis (Disease Ontology:DOID:1485); acute chest syndrome (Disease Ontology:DOID:1584); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); congenital heart disease (Disease Ontology:DOID:1682); ovary epithelial cancer (Disease Ontology:DOID:2152); motor neuron disease (Disease Ontology:DOID:231); colon adenocarcinoma (Disease Ontology:DOID:234); anemia (Disease Ontology:DOID:2355); multiple sclerosis (Disease Ontology:DOID:2377); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); cervix carcinoma (Disease Ontology:DOID:2893); pulmonary tuberculosis (Disease Ontology:DOID:2957); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); atopic dermatitis (Disease Ontology:DOID:3310); coronary artery disease (Disease Ontology:DOID:3393); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); Lynch syndrome (Disease Ontology:DOID:3883); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); liver disease (Disease Ontology:DOID:409); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); esophagus adenocarcinoma (Disease Ontology:DOID:4914); esophageal cancer (Disease Ontology:DOID:5041); liver cirrhosis (Disease Ontology:DOID:5082); peripheral nervous system disease (Disease Ontology:DOID:574); oral submucous fibrosis (Disease Ontology:DOID:5773); leukopenia (Disease Ontology:DOID:615); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783); cataract (Disease Ontology:DOID:83); lung disease (Disease Ontology:DOID:850); Hodgkin's lymphoma (Disease Ontology:DOID:8567); infectious mononucleosis (Disease Ontology:DOID:8568); ulcerative colitis (Disease Ontology:DOID:8577); oral cavity cancer (Disease Ontology:DOID:8618); myeloid leukemia (Disease Ontology:DOID:8692); Crohn's disease (Disease Ontology:DOID:8778); skin melanoma (Disease Ontology:DOID:8923); diabetic retinopathy (Disease Ontology:DOID:8947); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); oral mucosa leukoplakia (Disease Ontology:DOID:9655); senile cataract (Disease Ontology:DOID:9669); type 1 diabetes mellitus (Disease Ontology:DOID:9744); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); obesity (Disease Ontology:DOID:9970)",
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        "disease_count": 93,
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            {
                "id": "1.11.1.9",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9",
                "type": "external"
            },
            {
                "id": "2.5.1.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18",
                "type": "external"
            },
            {
                "id": "5.2.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2",
                "type": "external"
            },
            {
                "id": "1.8.5.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1",
                "type": "external"
            },
            {
                "id": "1.5.4.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.4.1",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004602 glutathione peroxidase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006749 glutathione metabolic process",
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    },
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            {
                "id": "A1Z7X8_DROME",
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        ],
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        "length": 313,
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        "gene_name": "Dmel\\CG12926",
        "organism": "Fruit fly",
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            {
                "id": "NP_610510",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610510",
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            }
        ],
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        "gene_names_refseq": "CG12926; Dmel\\CG12926",
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        "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding;GO:0120013 lipid transfer activity",
        "go_cellular_component": "GO:0005770 late endosome",
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        ],
        "mass": 43603.0,
        "length": 386,
        "protein_name": "Fanconi anaemia group A protein N-terminal domain-containing protein",
        "gene_name": "Dmel\\CG30001",
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            {
                "id": "NP_724825",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724825",
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            }
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        "gene_names_refseq": "CG30001; Dmel\\CG30001",
        "protein_names_uniprotkb": "Fanconi anaemia group A protein N-terminal domain-containing protein",
        "protein_names_refseq": "CG30001-PA; uncharacterized protein",
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        ],
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        "length": 340,
        "protein_name": "1.7.-.-; Mitochondrial amidoxime reducing component",
        "gene_name": "Marc",
        "organism": "Fruit fly",
        "refseq_name": "mitochondrial amidoxime reducing component",
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            {
                "id": "NP_610523",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610523",
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            }
        ],
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        "gene_names_refseq": "CG1665; Dmel\\CG1665; IP19920p; Marc; mArc",
        "protein_names_uniprotkb": "1.7.-.-; Mitochondrial amidoxime reducing component",
        "protein_names_refseq": "CG1665-PA; Marc-PA; mitochondrial amidoxime reducing component",
        "tax_id": 7227,
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        "go_cellular_component": "GO:0005739 mitochondrion;GO:1903958 nitric-oxide synthase complex",
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        ],
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        "length": 165,
        "protein_name": "MD-2-related lipid-recognition domain-containing protein",
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        "organism": "Fruit fly",
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            {
                "id": "NP_995798",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_995798",
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        ],
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        "gene_names_refseq": "CG33476; Dmel\\CG33476",
        "protein_names_uniprotkb": "MD-2-related lipid-recognition domain-containing protein",
        "protein_names_refseq": "CG33476-PA; uncharacterized protein",
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        "protein_name": "N-terminal E2 ubiquitin-conjugating enzyme",
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        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform E",
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            {
                "id": "NP_001097261",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097261",
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        "gene_names_refseq": "BEST:GH28095; BcDNA:GH28095; CG7220; Dmel\\CG7220; Ube2W",
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        "protein_names_refseq": "CG7220-PE; uncharacterized protein, isoform E",
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                "id": "NP_001096960",
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                "id": "NP_001096987",
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        "disease": "hypomyelinating leukodystrophy (Disease Ontology:DOID:0060786); hypomyelinating leukodystrophy 7 (Disease Ontology:DOID:0060794); Wiedemann-Rautenstrauch syndrome (Disease Ontology:DOID:0081333)",
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        "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0045727 positive regulation of translation;GO:0045945 positive regulation of transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006386 termination of RNA polymerase III transcription",
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                "id": "NP_001137967",
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    },
    {
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        "uniprot_id": [
            {
                "id": "O96881_DROME",
                "url": "https://www.uniprot.org/uniprot/O96881",
                "type": "external"
            }
        ],
        "mass": 33390.0,
        "length": 292,
        "protein_name": "Transcription initiation factor IIE subunit beta",
        "gene_name": "TfIIEbeta",
        "organism": "Fruit fly",
        "refseq_name": "transcription factor IIEbeta, isoform A",
        "refseq_ac": [
            {
                "id": "NP_523923",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523923",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "TfIIEbeta; CG1276; Dmel\\CG1276; Dmel_CG1276; E[[S]]; TFIIEbeta; TFIIE; TFIIbeta; TfIIE-beta; TfIIE; dTFIIE-S; dTFIIES",
        "gene_names_refseq": "CG1276; Dmel\\CG1276; E[[S]]; TFIIEbeta; TFIIE; TFIIbeta; TfIIEbeta; TfIIE; dTFIIE-S; dTFIIES",
        "protein_names_uniprotkb": "Transcription initiation factor IIE subunit beta",
        "protein_names_refseq": "CG1276-PA; TFIIE small subunit; TfIIEbeta-PA; transcription factor IIEbeta, isoform A",
        "tax_id": 7227,
        "disease": "nonphotosensitive trichothiodystrophy 6 (Disease Ontology:DOID:0111872)",
        "pathway": " (dme:Dmel_CG1276);  (R-DME-674695);  (R-DME-6807505);  (R-DME-73776);  (R-DME-73779);  (R-DME-75953);  (R-DME-76042)",
        "pathway_count": 7,
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        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity",
        "go_cellular_component": "GO:0005673 transcription factor TFIIE complex;GO:0005634 nucleus",
        "go_biological_process": "GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0042789 mRNA transcription by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly",
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    },
    {
        "uniprot_canonical_ac": "E2QCS7-1",
        "uniprot_id": [
            {
                "id": "E2QCS7_DROME",
                "url": "https://www.uniprot.org/uniprot/E2QCS7",
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            }
        ],
        "mass": 120554.0,
        "length": 1087,
        "protein_name": "AB hydrolase-1 domain-containing protein",
        "gene_name": "Dmel\\CG17097",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_609429",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609429",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG17097; CG17097; Dmel_CG17097; anon-SAGE:Wang-018",
        "gene_names_refseq": "CG17097; Dmel\\CG17097; anon-SAGE:Wang-018",
        "protein_names_uniprotkb": "AB hydrolase-1 domain-containing protein",
        "protein_names_refseq": "CG17097-PB; anon-SAGE:Wang-018; uncharacterized protein",
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        "disease": "",
        "pathway": " (dme:Dmel_CG17097);  (R-DME-192456);  (R-DME-6809371)",
        "pathway_count": 3,
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        "function": "",
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        "go_molecular_function": "GO:0016298 lipase activity;GO:0017171 serine hydrolase activity;GO:0004806 triacylglycerol lipase activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0007320 insemination;GO:0006629 lipid metabolic process;GO:0016042 lipid catabolic process;GO:0007618 mating",
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        "filter_code": "0000000.0000101.010000.000000100000000000.0100000000000.000.00000",
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    },
    {
        "uniprot_canonical_ac": "H9XVM3-1",
        "uniprot_id": [
            {
                "id": "H9XVM3_DROME",
                "url": "https://www.uniprot.org/uniprot/H9XVM3",
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            }
        ],
        "mass": 34659.0,
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        "protein_name": "ADP-ribosylation factor-like protein 11",
        "gene_name": "Arl4",
        "organism": "Fruit fly",
        "refseq_name": "ADP ribosylation factor-like 4, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001245408",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245408",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Arl4; ARL4B; BcDNA:AT26185; CG 2219; CG2219; Dmel\\CG2219; Dmel_CG2219; Q9V4B2; arl4",
        "gene_names_refseq": "ARL4B; Arl4; BcDNA:AT26185; CG 2219; CG2219; Dmel\\CG2219; Q9V4B2; arl4",
        "protein_names_uniprotkb": "ADP-ribosylation factor-like protein 11",
        "protein_names_refseq": "ADP ribosylation factor-like 4, isoform B; Arl4-PB; CG2219-PB",
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        "pathway": " (dme:Dmel_CG2219)",
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        "function": "May play a role in apoptosis. May act as a tumor suppressor., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_biological_process": "GO:0048731 system development;GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0051649 establishment of localization in cell",
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        ],
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                "id": "NP_001188828",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188828",
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            }
        ],
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        ],
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        ],
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259634",
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        ],
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        "protein_name": "Cyclin-H",
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        "refseq_ac": [
            {
                "id": "NP_524207",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524207",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "CycH; 142767_at; CCNH; CG7405; Dmel\\CG7405; Dmel_CG7405",
        "gene_names_refseq": "142767_at; CCNH; CG7405; CycH; Dmel\\CG7405",
        "protein_names_uniprotkb": "Cyclin-H",
        "protein_names_refseq": "CG7405-PA; CycH-PA; CyclinH; cyclin H; cyclin-H",
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        "disease": "transient cerebral ischemia (Disease Ontology:DOID:224)",
        "pathway": " (dme:Dmel_CG7405);  (R-DME-112382);  (R-DME-113418);  (R-DME-5696395);  (R-DME-674695);  (R-DME-6781823);  (R-DME-6782135);  (R-DME-6782210);  (R-DME-6796648);  (R-DME-69200);  (R-DME-69202);  (R-DME-69231);  (R-DME-69273);  (R-DME-69656);  (R-DME-72086);  (R-DME-73772);  (R-DME-73776);  (R-DME-73779);  (R-DME-75953);  (R-DME-75955);  (R-DME-76042);  (R-DME-77075);  (R-DME-8939236)",
        "pathway_count": 23,
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        "class_list": "",
        "function": "Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005675 transcription factor TFIIH holo complex;GO:0070985 transcription factor TFIIK complex;GO:0032806 carboxy-terminal domain protein kinase complex",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006289 nucleotide-excision repair",
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    },
    {
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            {
                "id": "O76901_DROME",
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        ],
        "mass": 27081.0,
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        "protein_name": "Rab27, isoform B",
        "gene_name": "Rab27",
        "organism": "Fruit fly",
        "refseq_name": "Rab27, isoform B",
        "refseq_ac": [
            {
                "id": "NP_726743",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726743",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Rab27; 18543235; AAF45634; AAF45635; CG14791; DmRab27; Dmel\\CG14791; Dmel_CG14791; EG:80H7.4; O76901; dm-Rab27; rab27",
        "gene_names_refseq": "18543235; AAF45634; AAF45635; CG14791; DmRab27; Dmel\\CG14791; EG:80H7.4; O76901; Rab27; dm-Rab27; rab27",
        "protein_names_uniprotkb": "Rab27, isoform B",
        "protein_names_refseq": "CG14791-PB; Rab27, isoform B; Rab27-PB",
        "tax_id": 7227,
        "disease": "hemophagocytic lymphohistiocytosis (Disease Ontology:DOID:0050120); Hermansky-Pudlak syndrome 1 (Disease Ontology:DOID:0060539); Griscelli syndrome type 2 (Disease Ontology:DOID:0060833); platelet storage pool deficiency (Disease Ontology:DOID:2223); non-Langerhans-cell histiocytosis (Disease Ontology:DOID:4330)",
        "pathway": " (dme:Dmel_CG14791);  (R-DME-114608);  (R-DME-6798695);  (R-DME-8873719);  (R-DME-8876198)",
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030141 secretory granule;GO:0045202 synapse;GO:0016324 apical plasma membrane;GO:0031982 vesicle",
        "go_biological_process": "GO:1990182 exosomal secretion;GO:0016192 vesicle-mediated transport;GO:0006887 exocytosis;GO:0032482 Rab protein signal transduction;GO:0045921 positive regulation of exocytosis",
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        ],
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        "protein_name": "Carmine, isoform A; Carmine, isoform B",
        "gene_name": "cm",
        "organism": "Fruit fly",
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                "id": "NP_001259302",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259302",
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        ],
        "gene_names_uniprotkb": "cm; AP-3mu; AP-3; AP3mu3; CG3035; CG32731; Dmel\\CG3035; Dmel_CG3035; Dmu3; Mu3; ap-3; apm3; cg3035; l(1)VEM119; mu3",
        "gene_names_refseq": "AP-3mu; AP-3; AP3mu3; CG3035; CG32731; Dmel\\CG3035; Dmu3; Mu3; ap-3; apm3; cg3035; cm; l(1)VEM119; mu3",
        "protein_names_uniprotkb": "Carmine, isoform A; Carmine, isoform B",
        "protein_names_refseq": "CG3035-PB; adaptor protein complex 3, mu subunit; carmine, isoform B; carmine; cm-PB",
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                "id": "Q0E981_DROME",
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            }
        ],
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            {
                "id": "NP_610942",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610942",
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        ],
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        "protein_names_refseq": "CG8485-PA; SNF related kinase, isoform A; Snrk-PA",
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        "class_list": "",
        "function": "May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis., [UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            },
            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
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            {
                "id": "5.6.1.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8",
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            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
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            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
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                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
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            {
                "id": "2.7.11.12",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            }
        ],
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        ],
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            {
                "id": "NP_001163103",
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            }
        ],
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        "gene_names_refseq": "BcDNA:GH06348; BcDNA; CG1516; Dmel\\CG1516; PCB; PC; Q0E9E2_DROME; dPC; pcb",
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        "protein_names_refseq": "CG1516-PM; GH06348; PCB-PM; pyruvate carboxykinase; pyruvate carboxylase, isoform M; pyruvate carboxylase",
        "tax_id": 7227,
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        "class_list": "",
        "function": "Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second., [UniProtKB, UniProtKB]",
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                "id": "6.3.4.-",
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        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0009374 biotin binding;GO:0004736 pyruvate carboxylase activity",
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        ],
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        ],
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        "protein_name": "ABC transporter domain-containing protein",
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                "id": "NP_733058",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733058",
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        ],
        "gene_names_uniprotkb": "CG18633; BcDNA:GH19411; CG11764; CG18655; CG31121; DmCG31121; Dmel\\CG31121; Dmel_CG31121",
        "gene_names_refseq": "BcDNA:GH19411; CG11764; CG18633; CG18655; CG31121; DmCG31121; Dmel\\CG31121",
        "protein_names_uniprotkb": "ABC transporter domain-containing protein",
        "protein_names_refseq": "CG31121-PA; uncharacterized protein, isoform A",
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        "disease": "sitosterolemia 1 (Disease Ontology:DOID:0070634); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); sitosterolemia (Disease Ontology:DOID:0090019); familial hyperlipidemia (Disease Ontology:DOID:1168); secondary hyperparathyroidism (Disease Ontology:DOID:12466); erythropoietic protoporphyria (Disease Ontology:DOID:13270); cholestasis (Disease Ontology:DOID:13580); status epilepticus (Disease Ontology:DOID:1824); hyperuricemia (Disease Ontology:DOID:1920); arteriosclerosis (Disease Ontology:DOID:2349); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)",
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        ],
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        "protein_name": "Dolichol-phosphate mannosyltransferase subunit 3",
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                "type": "external"
            },
            {
                "id": "1.3.8.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5",
                "type": "external"
            },
            {
                "id": "1.1.1.41",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.41",
                "type": "external"
            },
            {
                "id": "2.8.3.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5",
                "type": "external"
            },
            {
                "id": "2.3.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.-.-",
                "type": "external"
            },
            {
                "id": "2.3.1.9",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9",
                "type": "external"
            },
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.43",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.43",
                "type": "external"
            },
            {
                "id": "4.2.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2",
                "type": "external"
            },
            {
                "id": "2.3.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.16",
                "type": "external"
            },
            {
                "id": "5.3.3.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.21",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045254 pyruvate dehydrogenase complex",
        "go_biological_process": "GO:0006086 pyruvate decarboxylation to acetyl-CoA",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "Q7K5K3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q7KMG7-1",
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            {
                "id": "Q7KMG7_DROME",
                "url": "https://www.uniprot.org/uniprot/Q7KMG7",
                "type": "external"
            }
        ],
        "mass": 28583.0,
        "length": 259,
        "protein_name": "DNA excision repair protein ERCC-1",
        "gene_name": "Ercc1",
        "organism": "Fruit fly",
        "refseq_name": "Ercc1",
        "refseq_ac": [
            {
                "id": "NP_477468",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477468",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Ercc1; CG10215; Dmel\\CG10215; Dmel_CG10215; ERCC1; ercc1",
        "gene_names_refseq": "CG10215; Dmel\\CG10215; ERCC1; Ercc1; ercc1",
        "protein_names_uniprotkb": "DNA excision repair protein ERCC-1",
        "protein_names_refseq": "CG10215-PA; Ercc1-PA; Ercc1",
        "tax_id": 7227,
        "disease": "XFE progeroid syndrome (Disease Ontology:DOID:0060590); cerebrooculofacioskeletal syndrome 4 (Disease Ontology:DOID:0080914); stomach cancer (Disease Ontology:DOID:10534); kidney failure (Disease Ontology:DOID:1074); azoospermia (Disease Ontology:DOID:14227); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovary epithelial cancer (Disease Ontology:DOID:2152); transient cerebral ischemia (Disease Ontology:DOID:224); anemia (Disease Ontology:DOID:2355); ovarian cancer (Disease Ontology:DOID:2394); high grade glioma (Disease Ontology:DOID:3070); osteosarcoma (Disease Ontology:DOID:3347); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); esophagus adenocarcinoma (Disease Ontology:DOID:4914); myelofibrosis (Disease Ontology:DOID:4971); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
        "pathway": " (dme:Dmel_CG10215);  (R-DME-5696395);  (R-DME-5696400);  (R-DME-6782135)",
        "pathway_count": 4,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4., [UniProtKB, UniProtKB]",
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        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding",
        "go_cellular_component": "GO:0000110 nucleotide-excision repair factor 1 complex;GO:0070522 ERCC4-ERCC1 complex;GO:0032991 protein-containing complex",
        "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0006312 mitotic recombination;GO:0032204 regulation of telomere maintenance;GO:0006302 double-strand break repair;GO:0070914 UV-damage excision repair",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q7KMG7-1",
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        "kg_view_protein": true
    },
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            {
                "id": "Q7KSF2_DROME",
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            }
        ],
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        "length": 148,
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        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
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            {
                "id": "NP_996225",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996225",
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            }
        ],
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        "gene_names_refseq": "CG33333; Dmel\\CG33333",
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        "protein_names_refseq": "CG33333-PA; uncharacterized protein",
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        "go_biological_process": "",
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        "kg_view_protein": true
    },
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        "uniprot_id": [
            {
                "id": "Q7KT06_DROME",
                "url": "https://www.uniprot.org/uniprot/Q7KT06",
                "type": "external"
            }
        ],
        "mass": 138721.0,
        "length": 1235,
        "protein_name": "2.7.10.1; Ret oncogene, isoform A; Ret oncogene, isoform B; Ret oncogene, isoform C",
        "gene_name": "Ret",
        "organism": "Fruit fly",
        "refseq_name": "Ret oncogene, isoform A",
        "refseq_ac": [
            {
                "id": "NP_477044",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477044",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Ret; CG1061; CG14396; D-ret; DRET; DRet; DmHD-59; DmRet; Dmel\\CG14396; Dmel_CG14396; Dret; HD-59; MEN2; RET; Reto; dRET; dRet; dret; ret",
        "gene_names_refseq": "CG1061; CG14396; D-ret; DRET; DRet; DmHD-59; DmRet; Dmel\\CG14396; Dret; HD-59; MEN2; RET; Reto; Ret; dRET; dRet; dret; ret",
        "protein_names_uniprotkb": "2.7.10.1; Ret oncogene, isoform A; Ret oncogene, isoform B; Ret oncogene, isoform C",
        "protein_names_refseq": "CG14396-PA; Ret oncogene, isoform A; Ret-PA; dret",
        "tax_id": 7227,
        "disease": "multiple endocrine neoplasia type 2A (Disease Ontology:DOID:0050430); familial medullary thyroid carcinoma (Disease Ontology:DOID:0050547); pheochromocytoma (Disease Ontology:DOID:0050771); renal hypoplasia (Disease Ontology:DOID:0080204); Parkinsonism (Disease Ontology:DOID:0080855); multiple endocrine neoplasia type 2B (Disease Ontology:DOID:10016); Hirschsprung's disease (Disease Ontology:DOID:10487); clubfoot (Disease Ontology:DOID:11836); cancer (Disease Ontology:DOID:162); pancreatic cancer (Disease Ontology:DOID:1793); brain ischemia (Disease Ontology:DOID:2316)",
        "pathway": " (dme:Dmel_CG14396);  (R-DME-210993);  (R-DME-5673001);  (R-DME-8853659)",
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        "publication_count": 11,
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        "ec_number_list": [
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                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
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            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
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            },
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                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
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                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
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            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
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            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
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            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
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            {
                "id": "3.2.1.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.21",
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                "id": "3.2.1.46",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.46",
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                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            }
        ],
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030425 dendrite;GO:0043235 receptor complex",
        "go_biological_process": "GO:0007015 actin filament organization;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0016358 dendrite development;GO:0050773 regulation of dendrite development;GO:0001954 positive regulation of cell-matrix adhesion",
        "synthesized_glycan_count": 0,
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    },
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        ],
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        "length": 485,
        "protein_name": "Dynein regulatory complex protein 10",
        "gene_name": "BcDNA:AT04844",
        "organism": "Fruit fly",
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                "id": "NP_995734",
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        ],
        "gene_names_uniprotkb": "BcDNA:AT04844; 38E.23; CG33322; CG9329; Dmel\\CG33322; Dmel_CG33322",
        "gene_names_refseq": "38E.23; BcDNA:AT04844; CG33322; CG9329; Dmel\\CG33322",
        "protein_names_uniprotkb": "Dynein regulatory complex protein 10",
        "protein_names_refseq": "CG33322-PA; uncharacterized protein",
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        ],
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        "length": 455,
        "protein_name": "Uncharacterized protein",
        "gene_name": "CT18477",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285981",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285981",
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        ],
        "gene_names_uniprotkb": "CT18477; BG:DS02780.1; CG5888; Dmel\\CG5888; Dmel_CG5888",
        "gene_names_refseq": "BG:DS02780.1; CG5888; CT18477; Dmel\\CG5888",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG5888-PB; uncharacterized protein, isoform B",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0052381 tRNA dimethylallyltransferase activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006400 tRNA modification;GO:0070900 mitochondrial tRNA modification",
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        "hit_score": 1.2,
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    },
    {
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            {
                "id": "Q8IMX8_DROME",
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        ],
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        "protein_name": "U6 snRNA-associated Sm-like protein LSm3",
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        "refseq_name": "uncharacterized protein",
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            {
                "id": "NP_001163707",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163707",
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            }
        ],
        "gene_names_uniprotkb": "LSm3; BcDNA:RE11655; CG31184; CG5926; Dmel\\CG31184; Dmel_CG31184; LSM3; Lsm3",
        "gene_names_refseq": "BcDNA:RE11655; CG31184; CG5926; Dmel\\CG31184; LSm3; Lsm3",
        "protein_names_uniprotkb": "U6 snRNA-associated Sm-like protein LSm3",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "Binds specifically to the 3'-terminal U-tract of U6 snRNA., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003723 RNA binding",
        "go_cellular_component": "GO:0000932 P-body;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome;GO:0120115 Lsm2-8 complex;GO:0046540 U4/U6 x U5 tri-snRNP complex",
        "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0033962 P-body assembly",
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    },
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        ],
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        "protein_name": "Elongation of very long chain fatty acids protein",
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        "refseq_name": "uncharacterized protein",
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            {
                "id": "NP_732912",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_732912",
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            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG31141; CG31141; Dmel_CG31141",
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        "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein; 2.3.1.199; Very-long-chain 3-oxoacyl-CoA synthase",
        "protein_names_refseq": "CG31141-PA; uncharacterized protein",
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            {
                "id": "2.3.1.199",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0009922 fatty acid elongase activity",
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        ],
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            {
                "id": "NP_001189229",
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        ],
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        "protein_names_refseq": "CG32856-PB; uncharacterized protein, isoform B",
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            {
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        ],
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        "protein_name": "Protein SYS1 homolog",
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        "refseq_name": "Sys1 golgi trafficking protein, isoform A",
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            {
                "id": "NP_649809",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649809",
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        ],
        "gene_names_uniprotkb": "Sys1; CG11753; Dmel\\CG11753; Dmel_CG11753; SYS1",
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        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005802 trans-Golgi network",
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        ],
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                "id": "NP_001287215",
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        ],
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                "id": "3.4.19.-",
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                "id": "3.4.-.-",
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                "id": "3.4.17.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.13",
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                "id": "3.2.1.-",
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                "id": "2.4.1.25",
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                "id": "3.2.1.33",
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                "id": "2.7.1.-",
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098552 side of membrane;GO:0005829 cytosol;GO:0005840 ribosome",
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        "gene_names_refseq": "CG17255; Dmel\\CG17255; nocte",
        "protein_names_uniprotkb": "No circadian temperature entrainment, isoform A; No circadian temperature entrainment, isoform B; No circadian temperature entrainment, isoform C",
        "protein_names_refseq": "CG17255-PC; no circadian temperature entrainment, isoform C; nocte-PC",
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                "id": "Q8IRD3_DROME",
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        ],
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        "length": 238,
        "protein_name": "Glutathione peroxidase",
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        "organism": "Fruit fly",
        "refseq_name": "glutathione peroxidase homolog with thioredoxin peroxidase activity, isoform D",
        "refseq_ac": [
            {
                "id": "NP_728869",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728869",
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            }
        ],
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        "gene_names_refseq": "CG12013; DmGPx; DmGpx; DmPHGPx; Dmel\\CG12013; GPx; GTPx-1; GTPx; Gpx; Gtpx-1; Gtpx; PGTPx; PHGPx; Tpx1; anon-WO0257455.17; dGPX4; phGpx; phgpx",
        "protein_names_uniprotkb": "Glutathione peroxidase",
        "protein_names_refseq": "CG12013-PD; Gtpx-PD; PHGPx with glutathione peroxidase activity; glutathione peroxidase I; glutathione peroxidase homolog with thioredoxin peroxidase activity, isoform D; glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase",
        "tax_id": 7227,
        "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); spondylometaphyseal dysplasia Sedaghatian type (Disease Ontology:DOID:0112298); pre-eclampsia (Disease Ontology:DOID:10591); nephrotic syndrome (Disease Ontology:DOID:1184); colon cancer (Disease Ontology:DOID:219); acute kidney failure (Disease Ontology:DOID:3021); gastric adenocarcinoma (Disease Ontology:DOID:3717); colorectal cancer (Disease Ontology:DOID:9256)",
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        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0012505 endomembrane system;GO:0005739 mitochondrion;GO:0005829 cytosol",
        "go_biological_process": "GO:0006979 response to oxidative stress;GO:0034599 cellular response to oxidative stress;GO:0034976 response to endoplasmic reticulum stress;GO:0036335 intestinal stem cell homeostasis",
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        "protein_name": "Cryptocephal, isoform A; Cryptocephal, isoform E",
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            {
                "id": "NP_001260672",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260672",
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        "protein_names_uniprotkb": "Cryptocephal, isoform A; Cryptocephal, isoform E",
        "protein_names_refseq": "CG8669-PE; crc-PE; cryptocephal, isoform E; cryptocephal",
        "tax_id": 7227,
        "disease": "prostate carcinoma (Disease Ontology:DOID:10286); borna disease (Disease Ontology:DOID:5154); pulmonary venoocclusive disease (Disease Ontology:DOID:5453)",
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            {
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            {
                "id": "NP_001303494",
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        "protein_names_uniprotkb": "Canoe, isoform E; Canoe, isoform J",
        "protein_names_refseq": "CG42312-PJ; afadin; canoe, isoform J; canoe; cno-PJ; dorsal holes A; lips; misty",
        "tax_id": 7227,
        "disease": "Parkinson's disease (Disease Ontology:DOID:14330); breast carcinoma (Disease Ontology:DOID:3459)",
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        "gene_names_refseq": "CG14408; Dmel\\CG14408",
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        "protein_names_refseq": "CG14408-PH; uncharacterized protein, isoform H",
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        "protein_name": "Peptidase M14 domain-containing protein",
        "gene_name": "CG15768; CG15769",
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            {
                "id": "NP_572260",
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        "disease": "familial temporal lobe epilepsy 5 (Disease Ontology:DOID:0060752); familial febrile seizures 11 (Disease Ontology:DOID:0111308); nephrotic syndrome (Disease Ontology:DOID:1184); Behcet's disease (Disease Ontology:DOID:13241); thrombocytosis (Disease Ontology:DOID:2228); pancreatitis (Disease Ontology:DOID:4989); chronic kidney disease (Disease Ontology:DOID:784); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dme:Dmel_CG42264);  (R-DME-2022377)",
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    },
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            {
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        ],
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        "length": 1144,
        "protein_name": "Eukaryotic translation initiation factor 5B",
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        "refseq_name": "eukaryotic translation initiation factor 5B, isoform C",
        "refseq_ac": [
            {
                "id": "NP_001246599",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246599",
                "type": "external"
            }
        ],
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        "gene_names_refseq": "A1; CG10840; CG14970; Dmel\\CG10840; EIF5B; Eif5b; IF2; anon-WO0118547.362; cIF2; dIF2; eIF5B; yIF2",
        "protein_names_uniprotkb": "Eukaryotic translation initiation factor 5B; 3.6.5.3; Translation initiation factor IF-2",
        "protein_names_refseq": "CG10840-PC; cytoplasmic initiation factor 2; eIF5B-PC; eukaryotic initiation factor 5B; eukaryotic translation initiation factor 5B, isoform C",
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        "pathway": " (dme:Dmel_CG10840);  (R-DME-72706)",
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        "function": "Plays a role in translation initiation. Ribosome-dependent GTPase that promotes the joining of the 60S ribosomal subunit to the pre-initiation complex to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. Together with eIF1A (EIF1AX), actively orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after formation of the 80S initiation complex. Its GTPase activity is not essential for ribosomal subunits joining, but GTP hydrolysis is needed for eIF1A (EIF1AX) ejection quickly followed by EIF5B release to form elongation-competent ribosomes. In contrast to its procaryotic homolog, does not promote recruitment of Met-rRNA to the small ribosomal subunit., [UniProtKB, UniProtKB]",
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            {
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        "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex",
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        "protein_names_refseq": "CG9932-PA; elongation factor 4a; uncharacterized protein, isoform A",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0030915 Smc5-Smc6 complex",
        "go_biological_process": "GO:0006974 DNA damage response;GO:0006281 DNA repair;GO:0000724 double-strand break repair via homologous recombination;GO:0140588 chromatin looping",
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    },
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            {
                "id": "Q8IPM1_DROME",
                "url": "https://www.uniprot.org/uniprot/Q8IPM1",
                "type": "external"
            }
        ],
        "mass": 118784.0,
        "length": 1067,
        "protein_name": "Spargel, isoform B; Spargel, isoform E",
        "gene_name": "srl",
        "organism": "Fruit fly",
        "refseq_name": "spargel, isoform E",
        "refseq_ac": [
            {
                "id": "NP_649469",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649469",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "srl; CG 9809; CG9809; DmPGC-1alpha; DmPGC-1; Dmel\\CG9809; Dmel_CG9809; PCG1-alpha; PGC-1-alpha; PGC-1alpha; PGC-1; PGC1-alpha; PGC1a; PGC1; Spargel; Srl; cg9809; dPCG1alpha; dPGC-1alpha; dPGC-1; dPGC1; dPGC; dh-PPRC1; spargel",
        "gene_names_refseq": "CG 9809; CG9809; DmPGC-1/spargel; DmPGC-1alpha; DmPGC-1; Dmel\\CG9809; PCG1-alpha; PGC-1-alpha; PGC-1alpha; PGC-1; PGC1-alpha; PGC1a; PGC1; Spargel; Srl; cg9809; dPCG1alpha; dPGC-1alpha; dPGC-1; dPGC1; dPGC; dh-PPRC1; srl",
        "protein_names_uniprotkb": "Spargel, isoform B; Spargel, isoform E",
        "protein_names_refseq": "CG9809-PE; PGC-1/spargel; PPARG coactivator 1alpha; PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1; peroxisome proliferator-activated receptor gamma coactivator-1alpha; spargel, isoform E; srl-PE",
        "tax_id": 7227,
        "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); cardiomyopathy (Disease Ontology:DOID:0050700); renal fibrosis (Disease Ontology:DOID:0050855); colitis (Disease Ontology:DOID:0060180); abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); amblyopia (Disease Ontology:DOID:10376); Alzheimer's disease (Disease Ontology:DOID:10652); kidney failure (Disease Ontology:DOID:1074); age related macular degeneration (Disease Ontology:DOID:10871); amnestic disorder (Disease Ontology:DOID:10914); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); prediabetes syndrome (Disease Ontology:DOID:11716); nephrotic syndrome (Disease Ontology:DOID:1184); morbid obesity (Disease Ontology:DOID:11981); primary biliary cholangitis (Disease Ontology:DOID:12236); Huntington's disease (Disease Ontology:DOID:12858); cardiovascular system disease (Disease Ontology:DOID:1287); dilated cardiomyopathy (Disease Ontology:DOID:12930); Parkinson's disease (Disease Ontology:DOID:14330); malignant fibrous histiocytoma (Disease Ontology:DOID:1907); melanoma (Disease Ontology:DOID:1909); kidney cancer (Disease Ontology:DOID:263); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); placental insufficiency (Disease Ontology:DOID:3891); hyperglycemia (Disease Ontology:DOID:4195); macular degeneration (Disease Ontology:DOID:4448); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hyperthyroidism (Disease Ontology:DOID:7998); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dme:Dmel_CG9809);  (R-DME-9841922)",
        "pathway_count": 2,
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        "go_molecular_function": "GO:0003729 mRNA binding;GO:0003712 transcription coregulator activity;GO:0003713 transcription coactivator activity",
        "go_cellular_component": "GO:0016607 nuclear speck;GO:0005634 nucleus;GO:0005829 cytosol",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006979 response to oxidative stress;GO:0030307 positive regulation of cell growth;GO:0001894 tissue homeostasis;GO:0097009 energy homeostasis",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VNE3-1",
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            {
                "id": "Q9VNE3_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VNE3",
                "type": "external"
            }
        ],
        "mass": 53192.0,
        "length": 478,
        "protein_name": "O-phosphoseryl-tRNA(Sec) selenium transferase",
        "gene_name": "SecS",
        "organism": "Fruit fly",
        "refseq_name": "Sec synthetase, isoform C",
        "refseq_ac": [
            {
                "id": "NP_649556",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649556",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "SecS; CG1427; Dmel\\CG1427; Dmel_CG1427",
        "gene_names_refseq": "CG1427; Dmel\\CG1427; SecS",
        "protein_names_uniprotkb": "O-phosphoseryl-tRNA(Sec) selenium transferase; 2.9.1.2; Selenocysteine synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase",
        "protein_names_refseq": "CG1427-PC; Sec synthetase, isoform C; SecS-PC",
        "tax_id": 7227,
        "disease": "pontocerebellar hypoplasia type 2D (Disease Ontology:DOID:0060270)",
        "pathway": " (dme:Dmel_CG1427)",
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        "class_list": "",
        "function": "Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "B6IDR0",
        "ec_number_list": [
            {
                "id": "2.-.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.-.-.-",
                "type": "external"
            },
            {
                "id": "2.9.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.9.1.2",
                "type": "external"
            },
            {
                "id": "2.9.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.9.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0098621 O-phosphoseryl-tRNA(Sec) selenium transferase activity;GO:0000049 tRNA binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0001717 conversion of seryl-tRNAsec to selenocys-tRNAsec;GO:0006412 translation;GO:0001514 selenocysteine incorporation",
        "synthesized_glycan_count": 0,
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        ],
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        "length": 475,
        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG7031",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001287474",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287474",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG7031; CG7031; Dmel_CG7031",
        "gene_names_refseq": "CG7031; Dmel\\CG7031",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG7031-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
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            {
                "id": "Q9VGI0_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VGI0",
                "type": "external"
            }
        ],
        "mass": 49296.0,
        "length": 426,
        "protein_name": "Histamine-gated chloride channel subunit 1, isoform A",
        "gene_name": "HisCl1",
        "organism": "Fruit fly",
        "refseq_name": "Histamine-gated chloride channel subunit 1, isoform A",
        "refseq_ac": [
            {
                "id": "NP_731632",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_731632",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "HisCl1; CG14723; CT34515; DMHisClalpha2; Dm-HCLB; DmHisCl1; Dmel\\CG14723; Dmel_CG14723; HA-CI II; HisCl-alpha2; HisCl; hclB; hisCl1; hiscl1",
        "gene_names_refseq": "CG14723; CT34515; DMHisClalpha2; Dm-HCLB; DmHisCl1; Dmel\\CG14723; HA-CI II; HisCl-alpha2; HisCl1; HisCl; hclB; hisCl1; hiscl1",
        "protein_names_uniprotkb": "Histamine-gated chloride channel subunit 1, isoform A",
        "protein_names_refseq": "CG14723-PA; HisCl1-PA; Histamine-gated chloride channel subunit 1, isoform A; glycine receptor alpha3 subunit-like; histamine-gated chloride channel subunit 1",
        "tax_id": 7227,
        "disease": "hyperekplexia (Disease Ontology:DOID:0060695); hyperekplexia 1 (Disease Ontology:DOID:0060696); syndromic X-linked intellectual disability Pilorge type (Disease Ontology:DOID:0070422)",
        "pathway": " (dme:Dmel_CG14723);  (R-DME-112314)",
        "pathway_count": 2,
        "publication_count": 11,
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        "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity;GO:0019182 histamine-gated chloride channel activity;GO:0099095 ligand-gated monoatomic anion channel activity;GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0019183 histamine-gated chloride channel complex;GO:0098794 postsynapse",
        "go_biological_process": "GO:0006821 chloride transport;GO:0043052 thermotaxis;GO:1902476 chloride transmembrane transport",
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            {
                "id": "Q9VPZ7_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VPZ7",
                "type": "external"
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        ],
        "mass": 144665.0,
        "length": 1342,
        "protein_name": "Roundabout 3, isoform A",
        "gene_name": "robo3",
        "organism": "Fruit fly",
        "refseq_name": "roundabout 3, isoform A",
        "refseq_ac": [
            {
                "id": "NP_608592",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608592",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "robo3; CG14345; CG5423; CT17158; Dmel\\CG5423; Dmel_CG5423; ROBO3; Robo 3; Robo-3; Robo3; Robo; dRobo-3; robo-3; robo",
        "gene_names_refseq": "CG14345; CG5423; CT17158; Dmel\\CG5423; ROBO3; Robo 3; Robo-3; Robo3; Robo; dRobo-3; robo-3; robo3; robo",
        "protein_names_uniprotkb": "Roundabout 3, isoform A",
        "protein_names_refseq": "CG5423-PA; robo3-PA; roundabout 3, isoform A; roundabout 3",
        "tax_id": 7227,
        "disease": "atrial fibrillation (Disease Ontology:DOID:0060224); combined or isolated pituitary hormone deficiency 8 (Disease Ontology:DOID:0061018); autosomal recessive congenital nystagmus 8 (Disease Ontology:DOID:0061178); polymyositis (Disease Ontology:DOID:0080745); dermatomyositis (Disease Ontology:DOID:10223); pre-eclampsia (Disease Ontology:DOID:10591); lung cancer (Disease Ontology:DOID:1324); transient cerebral ischemia (Disease Ontology:DOID:224); cystic kidney disease (Disease Ontology:DOID:2975); plasmacytoma (Disease Ontology:DOID:3721); lung non-small cell carcinoma (Disease Ontology:DOID:3908); diabetic retinopathy (Disease Ontology:DOID:8947); multiple myeloma (Disease Ontology:DOID:9538); vesicoureteral reflux (Disease Ontology:DOID:9620)",
        "pathway": " (dme:Dmel_CG5423)",
        "pathway_count": 1,
        "publication_count": 11,
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            {
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        "protein_name": "Torn and diminished rhabdomeres, isoform D",
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        "protein_name": "Neuronal synaptobrevin",
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        "organism": "Fruit fly",
        "refseq_name": "neuronal synaptobrevin, isoform J",
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            {
                "id": "NP_001261269",
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        "protein_names_uniprotkb": "Neuronal synaptobrevin; n-syb",
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        "function": "Involved in the targeting and/or fusion of transport vesicles to their target membrane (PubMed:12364587, PubMed:22270918). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters (PubMed:12364587, PubMed:9482790). Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (PubMed:12364587). Also involved in a neuron-specific sort-and-degrade mechanism that promotes endolysosomal degradation and is required for neuronal maintenance (PubMed:22270918)., [UniProtKB, PubMed, PubMed, PubMed]",
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        "gene_names_refseq": "CG4365; Dmel\\CG4365; tzn",
        "protein_names_uniprotkb": "hydroxyacylglutathione hydrolase; 3.1.2.6; Glyoxalase II",
        "protein_names_refseq": "CG4365-PC; tenzing norgay, isoform C; tenzing norgay; tzn-PC",
        "tax_id": 7227,
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        "pathway": " (dme:Dmel_CG4365);  (R-DME-70268)",
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            {
                "id": "3.1.2.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.6",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004416 hydroxyacylglutathione hydrolase activity;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione;GO:0001666 response to hypoxia;GO:0031123 RNA 3'-end processing",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
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    },
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        "uniprot_canonical_ac": "Q9VM49-1",
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            {
                "id": "Q9VM49_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VM49",
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            }
        ],
        "mass": 66482.0,
        "length": 594,
        "protein_name": "Caper, isoform A; Caper, isoform B",
        "gene_name": "Caper",
        "organism": "Fruit fly",
        "refseq_name": "caper, isoform B",
        "refseq_ac": [
            {
                "id": "NP_609095",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609095",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Caper; CAPER; CC1.3; CG11266; Dmel\\CG11266; Dmel_CG11266; HCC1; cg11266; igru",
        "gene_names_refseq": "CAPER; CC1.3; CG11266; Caper; Dmel\\CG11266; HCC1; cg11266; igru",
        "protein_names_uniprotkb": "Caper, isoform A; Caper, isoform B",
        "protein_names_refseq": "CG11266-PB; Caper-PB; caper, isoform B; inselgruppe",
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        "pathway": " (dme:Dmel_CG11266);  (R-DME-9770562)",
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        "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000381 regulation of alternative mRNA splicing, via spliceosome",
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        "uniprot_canonical_ac": "Q9VHC7-1",
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                "id": "Q9VHC7_DROME",
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        ],
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        "length": 632,
        "protein_name": "Rumpelstiltskin, isoform A",
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        "refseq_name": "rumpelstiltskin, isoform A",
        "refseq_ac": [
            {
                "id": "NP_649899",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649899",
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        ],
        "gene_names_uniprotkb": "rump; CG9373; Dmel\\CG9373; Dmel_CG9373; HnRNP-S5; Hrp59; Rump; S5; cg9373; hnRNP M; hrp59; p70; p75",
        "gene_names_refseq": "CG9373; Dmel\\CG9373; HnRNP-S5; Hrp59; Rump; S5; cg9373; hnRNP M; hrp59; p70; p75; rump",
        "protein_names_uniprotkb": "Rumpelstiltskin, isoform A",
        "protein_names_refseq": "CG9373-PA; Hrp59; heterogeneous nuclear ribonucleoprotein M; heterogeneous nuclear ribonucleoprotein S5; p75; rump-PA; rumpelstiltskin, isoform A; rumpelstiltskin",
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        "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); leiomyoma (Disease Ontology:DOID:127)",
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        ],
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        "protein_name": "Ras-like protein family member 10B",
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        "refseq_name": "uncharacterized protein, isoform B",
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            {
                "id": "NP_001262281",
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        ],
        "gene_names_uniprotkb": "Dmel\\CG14669; Q9VNB7; CG14669; Dmel\\CG14669; Dmel_CG14669; Q9VNB7",
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        "protein_names_refseq": "CG14669-PB; uncharacterized protein, isoform B",
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
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        ],
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        "protein_name": "NTF2-related export protein",
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        "refseq_name": "nuclear transport factor-2, isoform E",
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            {
                "id": "NP_001259750",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259750",
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        ],
        "gene_names_uniprotkb": "Ntf-2; BcDNA:GM08921; CG1740; DNTF-2; Dmel\\CG1740; Dmel_CG1740; Dntf-2; Dntf2; NTF-2; Ntf2; dmNTF2; l(1)G0086; l(1)G0125; l(1)G0337; l(1)G0428; ntf-2; ntf2",
        "gene_names_refseq": "BcDNA:GM08921; CG1740; DNTF-2; Dmel\\CG1740; Dntf-2; Dntf2; NTF-2; Ntf-2; Ntf2; dmNTF2; l(1)G0086; l(1)G0125; l(1)G0337; l(1)G0428; ntf-2; ntf2",
        "protein_names_uniprotkb": "NTF2-related export protein",
        "protein_names_refseq": "CG1740-PE; Ntf-2-PE; nuclear transport factor-2, isoform E; nuclear transport factor-2",
        "tax_id": 7227,
        "disease": "diabetic retinopathy (Disease Ontology:DOID:8947)",
        "pathway": " (dme:Dmel_CG1740)",
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        "function": "Has a role in nuclear-cytoplasmic transport of proteins and mRNAs., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0061608 nuclear import signal receptor activity",
        "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0044613 nuclear pore central transport channel",
        "go_biological_process": "GO:0051028 mRNA transport;GO:0006606 protein import into nucleus;GO:0002807 positive regulation of antimicrobial peptide biosynthetic process",
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                "id": "Q9Y128_DROME",
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        ],
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        "protein_name": "Ceramide transfer protein",
        "gene_name": "cert",
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        "refseq_name": "ceramide transfer protein, isoform C",
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            {
                "id": "NP_001286978",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286978",
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        ],
        "gene_names_uniprotkb": "cert; BcDNA:GH07688; CERT; CG7207; Dcert; Dmel\\CG7207; Dmel_CG7207; dcert",
        "gene_names_refseq": "BcDNA:GH07688; CERT; CG7207; Dcert; Dmel\\CG7207; cert; dcert",
        "protein_names_uniprotkb": "Ceramide transfer protein; Collagen type IV alpha-3-binding protein",
        "protein_names_refseq": "CG7207-PC; ceramide transfer protein, isoform C; cert-PC",
        "tax_id": 7227,
        "disease": "autosomal dominant intellectual developmental disorder 34 (Disease Ontology:DOID:0070064)",
        "pathway": " (dme:Dmel_CG7207);  (R-DME-1660499)",
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        "go_molecular_function": "GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0097001 ceramide binding;GO:0120017 ceramide transfer activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005769 early endosome;GO:0005829 cytosol",
        "go_biological_process": "GO:0035627 ceramide transport;GO:0006665 sphingolipid metabolic process;GO:0035621 ER to Golgi ceramide transport;GO:0007032 endosome organization;GO:0001881 receptor recycling",
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        "protein_name": "AB hydrolase-1 domain-containing protein",
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        "refseq_name": "uncharacterized protein, isoform A",
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                "id": "NP_001163671",
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        "protein_names_refseq": "AMP-activated protein kinase gamma subunit; CG17299-PR; SNF4/AMP-activated protein kinase gamma subunit, isoform R; SNF4/AMP-activated protein kinase gamma; SNF4Agamma-PR; lethal (3) S005042; lethal (3) S012719; lochrig; loechrig",
        "tax_id": 7227,
        "disease": "lethal congenital glycogen storage disease of heart (Disease Ontology:DOID:0090101); hypertrophic cardiomyopathy 6 (Disease Ontology:DOID:0110312); neurodegenerative disease (Disease Ontology:DOID:1289); glycogen storage disease (Disease Ontology:DOID:2747); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384)",
        "pathway": " (R-DME-1632852);  (R-DME-380972);  (R-DME-5628897);  (R-DME-6804756)",
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            {
                "id": "NP_648288",
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        "refseq_name": "scavenger receptor class C, type I, isoform B",
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            {
                "id": "NP_001285599",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285599",
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            }
        ],
        "gene_names_uniprotkb": "Sr-CI; CG4099; CT9876; D-SR-CI; DSR-CI; Dmel\\CG4099; Dmel_CG4099; SR-C1; SR-CI; ScrCI; Sr-C1; Sr-CL; Sr-Cl; SrCl; dSR-C1; dSR-CI; dSRC-I; dScR-I",
        "gene_names_refseq": "CG4099; CT9876; D-SR-CI; DSR-CI; Dmel\\CG4099; SR-C1; SR-CI; ScrCI; Sr-C1; Sr-CI; Sr-CL; Sr-Cl; SrCl; dSR-C1; dSR-CI; dSRC-I; dScR-I",
        "protein_names_uniprotkb": "Scavenger receptor class C, type I, isoform A; Scavenger receptor class C, type I, isoform B",
        "protein_names_refseq": "CG4099-PB; Sr-CI-PB; scavenger receptor C, type I; scavenger receptor class C, type 1; scavenger receptor class C, type I, isoform B; scavenger receptor class V, type 1",
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        ],
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            {
                "id": "NP_609783",
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        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005768 endosome;GO:0005829 cytosol;GO:0005886 plasma membrane",
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        ],
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            {
                "id": "NP_609719",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609719",
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        ],
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        ],
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            {
                "id": "NP_647972",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647972",
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            }
        ],
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        "function": "Acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa-B-independent mechanisms. Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis., [UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "Twin of m4",
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        "refseq_name": "twin of m4",
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            {
                "id": "NP_524073",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524073",
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            }
        ],
        "gene_names_uniprotkb": "Tom; Bbu; CG5185; DmelCG5185; Dmel\\CG5185; Dmel_CG5185; anon-EST:fe1F6; barbu; tom",
        "gene_names_refseq": "Bbu; CG5185; DmelCG5185; Dmel\\CG5185; Tom; anon-EST:fe1F6; barbu; bbu/tom; tom",
        "protein_names_uniprotkb": "Twin of m4",
        "protein_names_refseq": "CG5185-PA; Tom-PA; anon-fast-evolving-1F6; barbu; twin of m4",
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        "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0001708 cell fate specification;GO:0007219 Notch signaling pathway;GO:0045746 negative regulation of Notch signaling pathway;GO:0016360 sensory organ precursor cell fate determination",
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        ],
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        "protein_name": "Crossover junction endonuclease MUS81",
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        "organism": "Fruit fly",
        "refseq_name": "mus81",
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            {
                "id": "NP_569873",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569873",
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        ],
        "gene_names_uniprotkb": "mus81; CG3026; Dmel\\CG3026; Dmel_CG3026; EG:BACR7A4.16; Mus81",
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        "protein_names_uniprotkb": "Crossover junction endonuclease MUS81; 3.1.22.-",
        "protein_names_refseq": "CG3026-PA; mus81-PA; mus81",
        "tax_id": 7227,
        "disease": "arterial tortuosity syndrome (Disease Ontology:DOID:0050645); Marfan syndrome (Disease Ontology:DOID:14323); pulmonary emphysema (Disease Ontology:DOID:9675)",
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        "class_list": "",
        "function": "Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI)., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0008821 crossover junction DNA endonuclease activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0048476 Holliday junction resolvase complex",
        "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0006281 DNA repair;GO:0031573 mitotic intra-S DNA damage checkpoint signaling;GO:0006308 DNA catabolic process;GO:0000727 double-strand break repair via break-induced replication",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "BG:BACR48E02.1",
        "organism": "Fruit fly",
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            {
                "id": "NP_609660",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609660",
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        ],
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            {
                "id": "NP_001260689",
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        "function": "Iron-sulfur cluster transfer protein involved in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) (PubMed:34950192). May deliver one or more Fe-S clusters to complex I subunits (By similarity). Alleviates pausing in mitochondrial DNA (mtDNA) replication at slow zone 2 (PubMed:34950192). May be involved in mtDNA-helicase-mediated mtDNA unwinding and replication by transferring iron-sulfur clusters (PubMed:34950192)., [UniProtKB, PubMed, UniProtKB]",
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            {
                "id": "Q9VAK5_DROME",
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        ],
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        "length": 212,
        "protein_name": "Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial",
        "gene_name": "ND-20L",
        "organism": "Fruit fly",
        "refseq_name": "NADH dehydrogenase (ubiquinone) 20 kDa subunit-like, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001287584",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287584",
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            }
        ],
        "gene_names_uniprotkb": "ND-20L; CG2014; Dmel\\CG2014; Dmel_CG2014; ND20-like; NUKM; dNDUFS7B",
        "gene_names_refseq": "CG2014; Dmel\\CG2014; ND-20L; ND20-like; NUKM; dNDUFS7B",
        "protein_names_uniprotkb": "Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial",
        "protein_names_refseq": "CG2014-PB; NADH dehydrogenase (ubiquinone) 20 kDa subunit-like, isoform B; NADH-ubiquinone oxidoreductase 20 kDa subunit; NADH: ubiquinone oxidoreductase-like, 20kDa subunit; NADH:ubiquinone oxidoreductase 20 kDa subunit; ND-20L-PB",
        "tax_id": 7227,
        "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); nuclear type mitochondrial complex I deficiency 3 (Disease Ontology:DOID:0112093); bipolar disorder (Disease Ontology:DOID:3312)",
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        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I",
        "go_biological_process": "GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0009060 aerobic respiration;GO:0015990 electron transport coupled proton transport",
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                "id": "Q9VAP1_DROME",
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        ],
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        "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13",
        "gene_name": "Alg13",
        "organism": "Fruit fly",
        "refseq_name": "Alg13 UDP-N-acetylglucosaminyltransferase subunit",
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            {
                "id": "NP_651673",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651673",
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            }
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        "gene_names_refseq": "Alg13; CG14512; Dmel\\CG14512; dAlg13",
        "protein_names_uniprotkb": "UDP-N-acetylglucosamine transferase subunit ALG13; 2.4.1.141",
        "protein_names_refseq": "Alg13 UDP-N-acetylglucosaminyltransferase subunit; Alg13-PA; CG14512-PA",
        "tax_id": 7227,
        "disease": "developmental and epileptic encephalopathy 36 (Disease Ontology:DOID:0080470)",
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        "class_list": "glycogene;glycosyltransferase",
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        "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0043541 UDP-N-acetylglucosamine transferase complex",
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        "protein_name": "eIF-4F 25 kDa subunit",
        "gene_name": "eIF4E6",
        "organism": "Fruit fly",
        "refseq_name": "eukaryotic translation initiation factor 4E6, isoform B",
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            {
                "id": "NP_001189306",
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        "gene_names_uniprotkb": "eIF4E6; BcDNA:RH55324; CG1442; Dmel\\CG1442; Dmel_CG1442; eIF4E-6; eIF4E",
        "gene_names_refseq": "BcDNA:RH55324; CG1442; Dmel\\CG1442; eIF4E-6; eIF4E6; eIF4E",
        "protein_names_uniprotkb": "eIF-4F 25 kDa subunit",
        "protein_names_refseq": "CG1442-PB; eIF4E-6; eIF4E6-PB; eukaryotic translation initiation factor 4E6, isoform B",
        "tax_id": 7227,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autistic disorder (Disease Ontology:DOID:12849); vascular dementia (Disease Ontology:DOID:8725)",
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        "length": 370,
        "protein_name": "3.-.-.-; Stress induced DNase",
        "gene_name": "Sid",
        "organism": "Fruit fly",
        "refseq_name": "stress induced DNase",
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            {
                "id": "NP_651627",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651627",
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            }
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        "gene_names_uniprotkb": "Sid; CG9989; Dmel\\CG9989; Dmel_CG9989; sid",
        "gene_names_refseq": "CG9989; Dmel\\CG9989; Sid; sid",
        "protein_names_uniprotkb": "3.-.-.-; Stress induced DNase",
        "protein_names_refseq": "CG9989-PA; Sid-PA; stress induced DNase",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0016020 membrane",
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        "protein_name": "Heat shock protein 83",
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                "id": "NP_651601",
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        "gene_names_uniprotkb": "Gp93; CG5520; CT17486; Dmel\\CG5520; Dmel_CG5520; GP93; HSP90B1; HSP90; Hsp90aa1; Hsp90; Q9VAY2; dGRP94; dHSP90; gp93; p93",
        "gene_names_refseq": "CG5520; CT17486; Dmel\\CG5520; GP93; Gp93; HSP90B1; HSP90; Hsp90aa1; Hsp90; Q9VAY2; dGRP94; dHSP90; gp93; p93",
        "protein_names_uniprotkb": "Heat shock protein 83; HSP 82",
        "protein_names_refseq": "CG5520-PA; Gp93-PA; glycoprotein 93; glycoprotein93; heat shock protein 90",
        "tax_id": 7227,
        "disease": "male infertility due to globozoospermia (Disease Ontology:DOID:0112312); lung adenocarcinoma (Disease Ontology:DOID:3910)",
        "pathway": " (dme:Dmel_CG5520);  (R-DME-381426);  (R-DME-6785807);  (R-DME-8957275)",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0048471 perinuclear region of cytoplasm;GO:0012505 endomembrane system",
        "go_biological_process": "GO:0061031 endodermal digestive tract morphogenesis;GO:0034605 cellular response to heat;GO:0007494 midgut development;GO:0006457 protein folding;GO:0036503 ERAD pathway",
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        ],
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        "length": 163,
        "protein_name": "MARVEL domain-containing protein",
        "gene_name": "Dmel\\CG12426",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_651591",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651591",
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        ],
        "gene_names_uniprotkb": "Dmel\\CG12426; CG12426; Dmel_CG12426",
        "gene_names_refseq": "CG12426; Dmel\\CG12426",
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        "protein_names_refseq": "CG12426-PB; uncharacterized protein",
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        "gene_names_refseq": "CG6296; DmelL7; Dmel\\CG6296",
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            {
                "id": "NP_001262999",
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        "protein_names_refseq": "'48' transcript; CG5507-PB; T48-PB; transcript 48, isoform B; transcript-48",
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                "id": "NP_733115",
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        "disease": "cryptorchidism (Disease Ontology:DOID:11383)",
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        "protein_names_uniprotkb": "Succinate-semialdehyde dehydrogenase; 1.2.1.24",
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        "function": "Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)., [UniProtKB, UniProtKB]",
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            {
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                "id": "NP_651335",
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        ],
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            {
                "id": "NP_001097911",
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        ],
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        "class_list": "glycogene;glycosyltransferase",
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        ],
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        ],
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            {
                "id": "NP_733077",
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            {
                "id": "NP_001287512",
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        "protein_name": "Methionine aminopeptidase",
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            {
                "id": "NP_651281",
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        ],
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        "gene_names_refseq": "CG13630; Dmel\\CG13630; MAP1A",
        "protein_names_uniprotkb": "Methionine aminopeptidase; 3.4.11.18",
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        "gene_names_refseq": "CG4374; Dmel\\CG4374",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "CG4374-PC; uncharacterized protein, isoform C",
        "tax_id": 7227,
        "disease": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
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    },
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            {
                "id": "Q9VCR4_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VCR4",
                "type": "external"
            }
        ],
        "mass": 90015.0,
        "length": 792,
        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG17111",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_651119",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651119",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG17111; CG17111; Dmel_CG17111",
        "gene_names_refseq": "CG17111; Dmel\\CG17111",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG17111-PB; uncharacterized protein",
        "tax_id": 7227,
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        "pathway": " (dme:Dmel_CG17111)",
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    },
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        ],
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        "protein_name": "Growth-blocking peptide 3, isoform A; Growth-blocking peptide 3, isoform B",
        "gene_name": "Gbp3",
        "organism": "Fruit fly",
        "refseq_name": "Growth-blocking peptide 3, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001287477",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287477",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Gbp3; BcDNA:RH17470; CG17244; Dmel\\CG17244; Dmel_CG17244; GBP3; GBP",
        "gene_names_refseq": "BcDNA:RH17470; CG17244; Dmel\\CG17244; GBP3; GBP; Gbp3",
        "protein_names_uniprotkb": "Growth-blocking peptide 3, isoform A; Growth-blocking peptide 3, isoform B",
        "protein_names_refseq": "CG17244-PB; Gbp3-PB; Growth-blocking peptide 3, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG17244)",
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        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
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                "id": "UBP12_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VCT9",
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            }
        ],
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        "length": 424,
        "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12/46 homolog",
        "gene_name": "Usp12-46",
        "organism": "Fruit fly",
        "refseq_name": "Ubiquitin-specific protease 12/46",
        "refseq_ac": [
            {
                "id": "NP_651099",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651099",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Usp12-46; 46; CG7023; Usp12; Usp46",
        "gene_names_refseq": "CG7023; Dmel\\CG7023; Q9VCT9; Usp12-46; Usp12/46; Usp12",
        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 12/46 homolog; 3.4.19.12; Ubiquitin-specific protease 12/46",
        "protein_names_refseq": "CG7023-PB; Ubiquitin-specific protease 12/46 ortholog; Ubiquitin-specific protease 12/46; Usp12-46-PB",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG7023);  (R-DME-5689880)",
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        "publication_id_list": "10731132;12537572;22778262;30266909;37798281",
        "class_list": "",
        "function": "Catalytic component of the Usp12-46 deubiquitylase complex (PubMed:37798281). Deubiquitylates the wg/wingless-signaling receptor arr/arrow, which stabilizes the receptor and increases its concentration at the cell surface; this enhances the sensitivity of cells to wg/wingless-signal stimulation (PubMed:37798281). This increases the amplitude and spatial range of the signaling response to the wg/wingless morphogen gradient, facilitating the precise, concentration-dependent regulation of its target genes (PubMed:37798281). Required for wg/wingless-mediated signaling in the wing imaginal disc and for wg/wingless-dependent regulation of adult intestinal stem cell proliferation (PubMed:37798281). Negative regulator of Notch signaling, possibly by regulating lysosomal degradation of N/Notch and affecting cell surface receptor levels; this may be context and cell-type specific function involved in external sensory organ development but not in wing imaginal-disc dorsoventral boundary signaling (Probable) (PubMed:22778262). Protects against HTT/huntingtin-induced polyglutamine expansion-dependent neurodegeneration (PubMed:30266909)., [UniProtKB, PubMed, PubMed, PubMed]",
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                "id": "3.4.19.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0101005 deubiquitinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:1905368 peptidase complex",
        "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0031647 regulation of protein stability;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VCV4-1",
        "uniprot_id": [
            {
                "id": "Q9VCV4_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VCV4",
                "type": "external"
            }
        ],
        "mass": 98804.0,
        "length": 902,
        "protein_name": "Cytoplasmic aconitate hydratase",
        "gene_name": "Irp-1A",
        "organism": "Fruit fly",
        "refseq_name": "iron regulatory protein 1A",
        "refseq_ac": [
            {
                "id": "NP_477371",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477371",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Irp-1A; C-Acon; CG4900; Dmel\\CG4900; Dmel_CG4900; IRF; IRP-1A; IRP-1; IRP1A; IRP1; IRP; c-Acon; cACON; cAcon; dIRP; irp1A",
        "gene_names_refseq": "C-Acon; CG4900; Dmel\\CG4900; IRF; IRP-1A; IRP-1; IRP1A; IRP1; IRP; Irp-1A; c-Acon; cACON; cAcon; dIRP; irp1A",
        "protein_names_uniprotkb": "Cytoplasmic aconitate hydratase; 4.2.1.3; Citrate hydro-lyase",
        "protein_names_refseq": "CG4900-PA; Irp-1A-PA; c-aconitase; cytoplasmic aconitase; cytosolic aconitase; iron regulatory factor; iron regulatory protein 1A; iron regulatory protein",
        "tax_id": 7227,
        "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Alzheimer's disease (Disease Ontology:DOID:10652); iron deficiency anemia (Disease Ontology:DOID:11758); porphyria (Disease Ontology:DOID:13268); duodenal ulcer (Disease Ontology:DOID:1724); hyperinsulinism (Disease Ontology:DOID:2018); anemia (Disease Ontology:DOID:2355); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
        "pathway": " (dme:Dmel_CG4900);  (R-DME-917937)",
        "pathway_count": 2,
        "publication_count": 11,
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        "biomarker_type": "",
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        "ec_number_list": [
            {
                "id": "4.2.1.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0030350 iron-responsive element binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol",
        "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0072350 tricarboxylic acid metabolic process;GO:0007370 ventral furrow formation",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VCV4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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                "id": "Q9VCY7_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VCY7",
                "type": "external"
            }
        ],
        "mass": 36883.0,
        "length": 322,
        "protein_name": "Elongation of very long chain fatty acids protein",
        "gene_name": "bond",
        "organism": "Fruit fly",
        "refseq_name": "james bond, isoform B",
        "refseq_ac": [
            {
                "id": "NP_651062",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651062",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bond; Bond; CG6921; Dmel\\CG6921; Dmel_CG6921; James bond",
        "gene_names_refseq": "Bond; CG6921; Dmel\\CG6921; James bond; bond",
        "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein; 2.3.1.199; Very-long-chain 3-oxoacyl-CoA synthase",
        "protein_names_refseq": "CG6921-PB; bond-PB; james bond, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG6921);  (R-DME-2046105);  (R-DME-2046106);  (R-DME-75876)",
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        "ec_number_list": [
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                "id": "2.3.1.199",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0009922 fatty acid elongase activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0051225 spindle assembly;GO:0000915 actomyosin contractile ring assembly;GO:0030497 fatty acid elongation;GO:0034625 fatty acid elongation, monounsaturated fatty acid",
        "synthesized_glycan_count": 0,
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        "record_id": "Q9VCY7-1",
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            }
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        ],
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                "id": "NP_524439",
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                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
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            },
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            },
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
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                "id": "2.7.11.11",
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            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
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            },
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                "id": "2.7.12.1",
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                "type": "external"
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            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
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            },
            {
                "id": "2.7.11.12",
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        "gene_names_refseq": "CG13420; CG31177; CG42335; CG5845; Dmel\\CG42335",
        "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-",
        "protein_names_refseq": "CG42335-PE; uncharacterized protein",
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            {
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        "function": "Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)., [UniProtKB, UniProtKB]",
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        "function": "Required for the assembly of the RNA endonuclease module of the integrator complex (PubMed:39032490). Associates with IntS9 and IntS11 in the cytoplasm and blocks the active site of IntS11, thereby inhibiting IntS11 endonuclease activity before formation of the full integrator complex (PubMed:39032490)., [UniProtKB, PubMed]",
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        "function": "Increases short-range diffusion of the wingless/wg protein, enhancing its signaling and expression of target genes required for wing margin morphogenesis (PubMed:34580289). May act as a serine protease inhibitor since it possess the Kazal serine protease inhibitor signature (Probable)., [UniProtKB, PubMed]",
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            {
                "id": "NP_650925",
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        ],
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            {
                "id": "NP_650732",
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        "protein_name": "Eukaryotic translation initiation factor 4C",
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        "refseq_name": "eukaryotic translation initiation factor 1A, isoform C",
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            {
                "id": "NP_001287386",
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        "gene_names_refseq": "CG8053; D-eIF1A; D-eIF4c; Dmel\\CG8053; EIF1A; EP(3)0935; EP935; Group I; anon-EST:Liang-2.3; anon-EST:Posey4; clone 2.3; eIF-1A; eIF-4c; eIF1A; group I; lincRNA.S7087",
        "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4C",
        "protein_names_refseq": "CG8053-PC; eIF1A-PC; eukaryotic initiation factor 1A; eukaryotic initiation factor 4c; eukaryotic translation initiation factor 1A, isoform C",
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        "disease": "uveal melanoma (Disease Ontology:DOID:6039)",
        "pathway": " (dme:Dmel_CG8053);  (R-DME-156827);  (R-DME-72649);  (R-DME-72689);  (R-DME-72695);  (R-DME-72702)",
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        "function": "Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016282 eukaryotic 43S preinitiation complex",
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                "id": "NP_650676",
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        "protein_names_refseq": "CG14316-PA; uncharacterized protein",
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        "protein_names_uniprotkb": "Tyramine receptor II, isoform A; Tyramine receptor II, isoform B; Tyramine receptor II, isoform C; Tyramine receptor II, isoform D",
        "protein_names_refseq": "CG16766-PB; TyrRII-PB; tyramine receptor II, isoform B; tyramine receptor",
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        "refseq_name": "curly Su",
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            {
                "id": "NP_650627",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650627",
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        "protein_names_uniprotkb": "1.11.1.-; Curly Su",
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        "disease": "lupus nephritis (Disease Ontology:DOID:0080162); Alzheimer's disease 1 (Disease Ontology:DOID:0080348); cardiovascular system disease (Disease Ontology:DOID:1287); lung cancer (Disease Ontology:DOID:1324); cystic fibrosis (Disease Ontology:DOID:1485); renovascular hypertension (Disease Ontology:DOID:1591); keratosis (Disease Ontology:DOID:161); cystitis (Disease Ontology:DOID:1679); pancreatic cancer (Disease Ontology:DOID:1793); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); acute kidney failure (Disease Ontology:DOID:3021); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); lung disease (Disease Ontology:DOID:850); vasculitis (Disease Ontology:DOID:865); bacterial pneumonia (Disease Ontology:DOID:874); status asthmaticus (Disease Ontology:DOID:9362)",
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        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "GckIII",
        "organism": "Fruit fly",
        "refseq_name": "germinal centre kinase III",
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            {
                "id": "NP_650596",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650596",
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            }
        ],
        "gene_names_uniprotkb": "GckIII; CG5169; Dmel\\CG5169; Dmel_CG5169; GCKIII; Gck III; STLK3; dGCKIII; dGckIII; wheezy",
        "gene_names_refseq": "CG5169; Dmel\\CG5169; GCKIII; Gck III; GckIII; STLK3; dGCKIII; dGckIII; wheezy",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "CG5169-PA; GckIII-PA; germinal center kinase III; germinal centre kinase III; wheezy",
        "tax_id": 7227,
        "disease": "cerebral cavernous malformation (Disease Ontology:DOID:0060669); nervous system disease (Disease Ontology:DOID:863)",
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        "ec_number_list": [
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            },
            {
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            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
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            },
            {
                "id": "3.4.22.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
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                "id": "5.6.1.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.8",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
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                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.11.25",
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                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
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                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
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            }
        ],
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus",
        "go_biological_process": "GO:0060439 trachea morphogenesis;GO:0035556 intracellular signal transduction;GO:0019991 septate junction assembly",
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    },
    {
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            {
                "id": "Q9VEP6_DROME",
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                "type": "external"
            }
        ],
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        "length": 481,
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        "gene_name": "Adsl",
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        "refseq_name": "adenylosuccinate lyase",
        "refseq_ac": [
            {
                "id": "NP_650586",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650586",
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            }
        ],
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        "protein_names_uniprotkb": "Adenylosuccinate lyase; 4.3.2.2; ASL; Adenylosuccinase",
        "protein_names_refseq": "Adsl-PA; CG3590-PA; adenylosuccinate lyase",
        "tax_id": 7227,
        "disease": "adenylosuccinase lyase deficiency (Disease Ontology:DOID:0050762); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612)",
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        "class_list": "",
        "function": "Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate., [UniProtKB, UniProtKB]",
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            }
        ],
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        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0006163 purine nucleotide metabolic process;GO:0006189 'de novo' IMP biosynthetic process;GO:0044208 'de novo' AMP biosynthetic process",
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            }
        ],
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            {
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    },
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        ],
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                "id": "NP_650533",
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        "go_molecular_function": "GO:0015149 hexose transmembrane transporter activity",
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        ],
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003681 bent DNA binding;GO:0003677 DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding",
        "go_cellular_component": "GO:0019185 snRNA-activating protein complex",
        "go_biological_process": "GO:0006383 transcription by RNA polymerase III;GO:0042795 snRNA transcription by RNA polymerase II;GO:0065004 protein-DNA complex assembly;GO:0042796 snRNA transcription by RNA polymerase III",
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    },
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            {
                "id": "Q9VF46_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VF46",
                "type": "external"
            }
        ],
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        "length": 218,
        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG5399",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
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            {
                "id": "NP_001262611",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262611",
                "type": "external"
            }
        ],
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        "gene_names_refseq": "CG5399; Dmel\\CG5399",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG5399-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
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            {
                "id": "Q9VF53_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VF53",
                "type": "external"
            }
        ],
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        "length": 1273,
        "protein_name": "1.-.-.-; 1.2.3.1; 1.2.3.8; Aldehyde oxidase 1",
        "gene_name": "AOX1",
        "organism": "Fruit fly",
        "refseq_name": "aldehyde oxidase 1",
        "refseq_ac": [
            {
                "id": "NP_650475",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650475",
                "type": "external"
            }
        ],
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        "gene_names_refseq": "AOX1; CG18522; CT42272; DmAO1; Dmel\\CG18522; LPO; PO; Po; lpo",
        "protein_names_uniprotkb": "1.-.-.-; 1.2.3.1; 1.2.3.8; Aldehyde oxidase 1",
        "protein_names_refseq": "AOX1-PA; CG18522-PA; aldehyde oxidase 1; low-pyridoxal-oxidase; pyridoxal oxidase",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG18522)",
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        "go_molecular_function": "GO:0005506 iron ion binding;GO:0071949 FAD binding;GO:0004031 aldehyde oxidase activity;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0016491 oxidoreductase activity",
        "go_cellular_component": "GO:0005777 peroxisome;GO:0005829 cytosol",
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        "protein_name": "Cerebral cavernous malformation 3",
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        "organism": "Fruit fly",
        "refseq_name": "cerebral cavernous malformation 3",
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            {
                "id": "NP_650459",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650459",
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            }
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        "gene_names_refseq": "CCM3; CG5073; Ccm3; Dmel\\CG5073",
        "protein_names_uniprotkb": "Cerebral cavernous malformation 3",
        "protein_names_refseq": "CG5073-PA; Ccm3-PA; cerebral cavernous malformation 3 ortholog; cerebral cavernous malformation 3",
        "tax_id": 7227,
        "disease": "cerebral cavernous malformation (Disease Ontology:DOID:0060669); cerebral cavernous malformation 3 (Disease Ontology:DOID:0060671); varicocele (Disease Ontology:DOID:12337); hepatitis (Disease Ontology:DOID:2237); endometrial adenocarcinoma (Disease Ontology:DOID:2870); liver cirrhosis (Disease Ontology:DOID:5082); liver carcinoma (Disease Ontology:DOID:686)",
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        "go_molecular_function": "GO:0019901 protein kinase binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0090443 FAR/SIN/STRIPAK complex",
        "go_biological_process": "GO:0035330 regulation of hippo signaling;GO:0060439 trachea morphogenesis;GO:0090168 Golgi reassembly",
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            {
                "id": "Q9VFC1_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VFC1",
                "type": "external"
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        ],
        "mass": 48775.0,
        "length": 426,
        "protein_name": "Serpin 88Eb",
        "gene_name": "Spn88Eb",
        "organism": "Fruit fly",
        "refseq_name": "serpin 88Eb",
        "refseq_ac": [
            {
                "id": "NP_650427",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650427",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Spn88Eb; CG6687; Dmel\\CG6687; Dmel_CG6687; Spn88EB; serpin",
        "gene_names_refseq": "CG6687; Dmel\\CG6687; Spn88EB; Spn88Eb; serpin",
        "protein_names_uniprotkb": "Serpin 88Eb",
        "protein_names_refseq": "CG6687-PA; Dm-serpin-88Eb; Spn88Eb-PA; serpin 88Eb",
        "tax_id": 7227,
        "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); familial encephalopathy with neuroserpin inclusion bodies (Disease Ontology:DOID:0050831); coarctation of the aorta (Disease Ontology:DOID:0051054); stroke (Disease Ontology:DOID:0051061); chemical colitis (Disease Ontology:DOID:0060186); ileitis (Disease Ontology:DOID:0060189); atrial fibrillation (Disease Ontology:DOID:0060224); thrombosis (Disease Ontology:DOID:0060903); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); Nagashima-type palmoplantar keratosis (Disease Ontology:DOID:0070555); polycystic kidney disease (Disease Ontology:DOID:0080322); corticosteroid-binding globulin deficiency (Disease Ontology:DOID:0090030); osteonecrosis (Disease Ontology:DOID:10159); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); gastric ulcer (Disease Ontology:DOID:10808); nephritis (Disease Ontology:DOID:10952); meconium aspiration syndrome (Disease Ontology:DOID:11049); hydronephrosis (Disease Ontology:DOID:11111); IgA vasculitis (Disease Ontology:DOID:11123); disseminated intravascular coagulation (Disease Ontology:DOID:11247); adult respiratory distress syndrome (Disease Ontology:DOID:11394); pulmonary edema (Disease Ontology:DOID:11396); sciatic neuropathy (Disease Ontology:DOID:11446); familial hyperlipidemia (Disease Ontology:DOID:1168); prediabetes syndrome (Disease Ontology:DOID:11716); nephrotic syndrome (Disease Ontology:DOID:1184); Creutzfeldt-Jakob disease (Disease Ontology:DOID:11949); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); allergic disease (Disease Ontology:DOID:1205); otosclerosis (Disease Ontology:DOID:12185); primary biliary cholangitis (Disease Ontology:DOID:12236); alcoholic hepatitis (Disease Ontology:DOID:12351); dilated cardiomyopathy (Disease Ontology:DOID:12930); retinopathy of prematurity (Disease Ontology:DOID:13025); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); uveitis (Disease Ontology:DOID:13141); alpha 1-antitrypsin deficiency (Disease Ontology:DOID:13372); sick sinus syndrome (Disease Ontology:DOID:13884); toxic shock syndrome (Disease Ontology:DOID:14115); Fabry disease (Disease Ontology:DOID:14499); cystic fibrosis (Disease Ontology:DOID:1485); diffuse scleroderma (Disease Ontology:DOID:1580); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); impotence (Disease Ontology:DOID:1875); atherosclerosis (Disease Ontology:DOID:1936); hyperinsulinism (Disease Ontology:DOID:2018); transient cerebral ischemia (Disease Ontology:DOID:224); arteriosclerosis (Disease Ontology:DOID:2349); multiple sclerosis (Disease Ontology:DOID:2377); ovarian cancer (Disease Ontology:DOID:2394); central retinal vein occlusion (Disease Ontology:DOID:2450); endometriosis (Disease Ontology:DOID:289); acute pancreatitis (Disease Ontology:DOID:2913); glomerulonephritis (Disease Ontology:DOID:2921); severe acute respiratory syndrome (Disease Ontology:DOID:2945); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328); coronary artery disease (Disease Ontology:DOID:3393); carotid artery disease (Disease Ontology:DOID:3407); middle cerebral artery infarction (Disease Ontology:DOID:3525); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); antithrombin III deficiency (Disease Ontology:DOID:3755); pulmonary fibrosis (Disease Ontology:DOID:3770); lung adenocarcinoma (Disease Ontology:DOID:3910); liver disease (Disease Ontology:DOID:409); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); cerebrovascular disease (Disease Ontology:DOID:6713); hepatocellular carcinoma (Disease Ontology:DOID:684); osteoarthritis (Disease Ontology:DOID:8398); chronic myeloid leukemia (Disease Ontology:DOID:8552); vasculitis (Disease Ontology:DOID:865); intermediate coronary syndrome (Disease Ontology:DOID:8805); skin melanoma (Disease Ontology:DOID:8923); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352); pulmonary emphysema (Disease Ontology:DOID:9675); mitral valve prolapse (Disease Ontology:DOID:988); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dme:Dmel_CG6687);  (R-DME-114608);  (R-DME-1650814);  (R-DME-381426);  (R-DME-6798695);  (R-DME-8939242);  (R-DME-8957275);  (R-DME-9855719);  (R-DME-9948001)",
        "pathway_count": 9,
        "publication_count": 12,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499",
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        "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0050776 regulation of immune response;GO:0045861 negative regulation of proteolysis;GO:0009620 response to fungus;GO:2000035 regulation of stem cell division;GO:1990399 epithelium regeneration",
        "synthesized_glycan_count": 0,
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        "uniprot_id": [
            {
                "id": "Q9VFC9_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VFC9",
                "type": "external"
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        ],
        "mass": 46061.0,
        "length": 404,
        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG3987",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_650421",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650421",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "Dmel\\CG3987; CG3987; Dmel_CG3987; anon-WO0140519.215",
        "gene_names_refseq": "CG3987; Dmel\\CG3987; anon-WO0140519.215",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG3987-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
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        "function": "Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4., [UniProtKB, UniProtKB]",
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        "protein_names_refseq": "CG8795-PA; PK2-R2-PA; pyrokinin 2 receptor 2, isoform A; pyrokinin 2 receptor",
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        "function": "Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system)., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005314 high-affinity L-glutamate transmembrane transporter activity;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle",
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    },
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            {
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            }
        ],
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        "gene_name": "Dmel\\CG14718",
        "organism": "Fruit fly",
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            {
                "id": "NP_650107",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650107",
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            }
        ],
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        "gene_names_refseq": "CG14718; Dmel\\CG14718; cg14718",
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        "go_cellular_component": "GO:0005634 nucleus",
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    },
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        ],
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                "id": "NP_650104",
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            }
        ],
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        ],
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        "length": 837,
        "protein_name": "GPI ethanolamine phosphate transferase 1",
        "gene_name": "Dmel\\CG5342",
        "organism": "Fruit fly",
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            {
                "id": "NP_650088",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650088",
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            }
        ],
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        "gene_names_refseq": "CG5342; Dmel\\CG5342",
        "protein_names_uniprotkb": "GPI ethanolamine phosphate transferase 1; 2.-.-.-",
        "protein_names_refseq": "CG5342-PB; uncharacterized protein",
        "tax_id": 7227,
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        "class_list": "",
        "function": "Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0051377 mannose-ethanolamine phosphotransferase activity",
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        ],
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            {
                "id": "NP_650083",
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            }
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        "protein_names_uniprotkb": "UDP-glucuronosyltransferase; 2.4.1.17",
        "protein_names_refseq": "CG6649-PA; UDP-glycosyltransferase 35b; UDP-glycosyltransferase family 35 member B1; Ugt35B1-PA",
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        ],
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        "protein_name": "UDP-glucuronosyltransferase",
        "gene_name": "Ugt35E1",
        "organism": "Fruit fly",
        "refseq_name": "UDP-glycosyltransferase family 35 member E1",
        "refseq_ac": [
            {
                "id": "NP_652622",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652622",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "Ugt35E1; AC 006491G; CG17200-PA; CG17200; Dmel\\CG17200; Dmel_CG17200; UGT35E1; Ugt86Dg",
        "gene_names_refseq": "AC 006491G; CG17200-PA; CG17200; Dmel\\CG17200; UGT35E1; Ugt35E1; Ugt86Dg",
        "protein_names_uniprotkb": "UDP-glucuronosyltransferase; 2.4.1.17",
        "protein_names_refseq": "CG17200-PB; UDP-glycosyltransferase 86Dg; UDP-glycosyltransferase family 35 member E1; Ugt35E1-PB; Ugt86Dg",
        "tax_id": 7227,
        "disease": "hepatitis B (Disease Ontology:DOID:2043); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dme:Dmel_CG17200);  (R-DME-9753281);  (R-DME-9757110);  (R-DME-9840309)",
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        "class_list": "glycogene;glycosyltransferase",
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        ],
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            {
                "id": "NP_649924",
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            }
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        "disease": "renal fibrosis (Disease Ontology:DOID:0050855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); nephrotic syndrome (Disease Ontology:DOID:1184); dilated cardiomyopathy (Disease Ontology:DOID:12930); acute kidney failure (Disease Ontology:DOID:3021); coronary artery disease (Disease Ontology:DOID:3393); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); double outlet right ventricle (Disease Ontology:DOID:6406); pulmonary hypertension (Disease Ontology:DOID:6432); hyperhomocysteinemia (Disease Ontology:DOID:9279)",
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        "protein_names_refseq": "CG8301-PA; uncharacterized protein",
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                "id": "NP_649897",
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        "protein_names_uniprotkb": "Alkaline phosphatase; 3.1.3.1",
        "protein_names_refseq": "CG8147-PA; alkaline phosphatase 3; phu-PA; phurba tashi",
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        "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); adult hypophosphatasia (Disease Ontology:DOID:0110913); infantile hypophosphatasia (Disease Ontology:DOID:0110914); childhood hypophosphatasia (Disease Ontology:DOID:0110915); familial combined hyperlipidemia (Disease Ontology:DOID:13809); hypophosphatasia (Disease Ontology:DOID:14213); arteriosclerosis (Disease Ontology:DOID:2349); uremia (Disease Ontology:DOID:4676); ulcerative colitis (Disease Ontology:DOID:8577); in situ carcinoma (Disease Ontology:DOID:8719); Crohn's disease (Disease Ontology:DOID:8778); steatotic liver disease (Disease Ontology:DOID:9452)",
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        "protein_name": "Salivary gland-expressed bHLH, isoform A; Salivary gland-expressed bHLH, isoform C",
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        "refseq_name": "salivary gland-expressed bHLH, isoform A",
        "refseq_ac": [
            {
                "id": "NP_524287",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524287",
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        "gene_names_uniprotkb": "sage; CG12952; Dmel\\CG12952; Dmel_CG12952; Sage; bHLHc7",
        "gene_names_refseq": "CG12952; Dmel\\CG12952; Sage; bHLHc7; sage",
        "protein_names_uniprotkb": "Salivary gland-expressed bHLH, isoform A; Salivary gland-expressed bHLH, isoform C",
        "protein_names_refseq": "CG12952-PA; sage-PA; salivary gland-expressed bHLH, isoform A",
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            {
                "id": "NP_649835",
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        "protein_names_uniprotkb": "T-complex protein 1 subunit eta; CCT-eta; TCP-1-eta",
        "protein_names_refseq": "CCT7-PA; CG8351-PA; TCP1-zeta homologue; Tcp-1eta; chaperonin containing TCP1 subunit 7",
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        ],
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        "protein_name": "Lysosomal Pro-X carboxypeptidase",
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        "function": "Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH., [UniProtKB, UniProtKB]",
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            {
                "id": "3.4.24.-",
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        ],
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        ],
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        ],
        "gene_names_uniprotkb": "mRpS18B; 38B.17; CG10757; Dmel\\CG10757; Dmel_CG10757; MRP-S18-(2); mRpS18b",
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        "protein_names_uniprotkb": "Small ribosomal subunit protein mS40; 28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial",
        "protein_names_refseq": "CG10757-PA; mRpS18B-PA; mitochondrial ribosomal protein S18B, isoform A; mitochondrial ribosomal protein S18b",
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    },
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            {
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        ],
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        "refseq_name": "inhibitor of growth family member 5, isoform B",
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            {
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        "protein_names_refseq": "CG5122-PA; uncharacterized protein",
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        "protein_name": "Ubiquitin conjugation factor E4 B",
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        "gene_names_refseq": "CG 9934; CG9934; Dmel\\CG9934; E4 B; UBE4B; UFD2b; Ube4B; Ube4b; dUfd2; ufd2",
        "protein_names_uniprotkb": "Ubiquitin conjugation factor E4 B; 2.3.2.27; RING-type E3 ubiquitin transferase E4 B; Ubiquitin fusion degradation protein 2",
        "protein_names_refseq": "CG9934-PB; NM 135753.2; Ube4B-PB; ubiquitination factor E4B, isoform B",
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                "id": "3.6.1.15",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303315",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG14277; CG14277; Dmel_CG14277",
        "gene_names_refseq": "CG14277; Dmel\\CG14277",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG14277-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG14277)",
        "pathway_count": 1,
        "publication_count": 11,
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        "reported_phosphosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VLQ6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VLS4-1",
        "uniprot_id": [
            {
                "id": "Q9VLS4_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VLS4",
                "type": "external"
            }
        ],
        "mass": 9916.0,
        "length": 90,
        "protein_name": "Acyl-CoA binding protein 1, isoform A; Acyl-CoA binding protein 1, isoform B",
        "gene_name": "Acbp1",
        "organism": "Fruit fly",
        "refseq_name": "Acyl-CoA binding protein 1, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285744",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285744",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Acbp1; ACBP; CG8498; DmCG8498; Dmel\\CG8498; Dmel_CG8498",
        "gene_names_refseq": "ACBP; Acbp1; CG8498; DmCG8498; Dmel\\CG8498",
        "protein_names_uniprotkb": "Acyl-CoA binding protein 1, isoform A; Acyl-CoA binding protein 1, isoform B",
        "protein_names_refseq": "Acbp1-PB; Acyl-CoA binding protein 1, isoform B; CG8498-PB; acyl-CoA-binding protein",
        "tax_id": 7227,
        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); cardiovascular system disease (Disease Ontology:DOID:1287); morphine dependence (Disease Ontology:DOID:2560)",
        "pathway": " (dme:Dmel_CG8498);  (R-DME-77289)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
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        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000062 fatty-acyl-CoA binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0019915 lipid storage",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VLS4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VLV9-1",
        "uniprot_id": [
            {
                "id": "Q9VLV9_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VLV9",
                "type": "external"
            }
        ],
        "mass": 15404.0,
        "length": 140,
        "protein_name": "Proctolin, isoform A; Proctolin, isoform B",
        "gene_name": "Proc",
        "organism": "Fruit fly",
        "refseq_name": "proctolin, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285728",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285728",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Proc; CG7105; Dmel\\CG7105; Dmel_CG7105; PROCT; PROC; Prct; Proct; proct; proc",
        "gene_names_refseq": "CG7105; Dmel\\CG7105; PROCT; PROC; Prct; Proct; Proc; proct; proc",
        "protein_names_uniprotkb": "Proctolin, isoform A; Proctolin, isoform B",
        "protein_names_refseq": "CG7105-PB; Proc-PB; proctolin, isoform B; proctolin",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG7105)",
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        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
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        "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0071860 proctolin receptor binding",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0010460 positive regulation of heart rate;GO:0040011 locomotion",
        "synthesized_glycan_count": 0,
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        "record_id": "Q9VLV9-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VLX0-1",
        "uniprot_id": [
            {
                "id": "Q9VLX0_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VLX0",
                "type": "external"
            }
        ],
        "mass": 103125.0,
        "length": 928,
        "protein_name": "Alpha-aminoadipic semialdehyde synthase, mitochondrial",
        "gene_name": "LKRSDH",
        "organism": "Fruit fly",
        "refseq_name": "lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285719",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285719",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LKRSDH; BEST:CK02318; CG7144; CK02318; Dmel\\CG7144; Dmel_CG7144; LKR; SDH; anon-WO0149856.1; dLKR; lys",
        "gene_names_refseq": "BEST:CK02318; CG7144; CK02318; Dmel\\CG7144; LKRSDH; LKR; SDH; anon-WO0149856.1; dLKR; lys",
        "protein_names_uniprotkb": "Alpha-aminoadipic semialdehyde synthase, mitochondrial; 1.5.1.8; 1.5.1.9; LKR/SDH",
        "protein_names_refseq": "CG7144-PB; LKRSDH-PB; drosophila lysine ketoglutarate reductase (dLKR)/saccharopine dehydrogenase (SDH); lysine ketoglutarate Reductase/Saccharopine dehydrogenase; lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform B; lysine ketoglutarate reductase; saccharopine dehydogenase",
        "tax_id": 7227,
        "disease": "hyperlysinemia (Disease Ontology:DOID:9274)",
        "pathway": " (dme:Dmel_CG7144);  (R-DME-71064)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Bifunctional enzyme that catalyzes the first two steps in lysine degradation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "ec_number_list": [
            {
                "id": "1.5.1.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.8",
                "type": "external"
            },
            {
                "id": "1.5.1.9",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.9",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004753 saccharopine dehydrogenase activity;GO:0047130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity;GO:0047131 saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity;GO:0003714 transcription corepressor activity;GO:0042393 histone binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006554 lysine catabolic process;GO:0019878 lysine biosynthetic process via aminoadipic acid;GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0019477 L-lysine catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VLX0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VLZ8-1",
        "uniprot_id": [
            {
                "id": "Q9VLZ8_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VLZ8",
                "type": "external"
            }
        ],
        "mass": 43246.0,
        "length": 378,
        "protein_name": "Serpin 28B, isoform A; Serpin 28B, isoform B",
        "gene_name": "Spn28B",
        "organism": "Fruit fly",
        "refseq_name": "serpin 28B, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001260209",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260209",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Spn28B; CG6717; Dmel\\CG6717; Dmel_CG6717; Spn7",
        "gene_names_refseq": "CG6717; Dmel\\CG6717; Spn28B; Spn7",
        "protein_names_uniprotkb": "Serpin 28B, isoform A; Serpin 28B, isoform B",
        "protein_names_refseq": "CG6717-PB; Spn28B-PB; serine protease inhibitor 7; serpin 28B, isoform B",
        "tax_id": 7227,
        "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); familial encephalopathy with neuroserpin inclusion bodies (Disease Ontology:DOID:0050831); coarctation of the aorta (Disease Ontology:DOID:0051054); stroke (Disease Ontology:DOID:0051061); chemical colitis (Disease Ontology:DOID:0060186); ileitis (Disease Ontology:DOID:0060189); atrial fibrillation (Disease Ontology:DOID:0060224); thrombosis (Disease Ontology:DOID:0060903); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); Nagashima-type palmoplantar keratosis (Disease Ontology:DOID:0070555); polycystic kidney disease (Disease Ontology:DOID:0080322); corticosteroid-binding globulin deficiency (Disease Ontology:DOID:0090030); osteonecrosis (Disease Ontology:DOID:10159); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); gastric ulcer (Disease Ontology:DOID:10808); nephritis (Disease Ontology:DOID:10952); meconium aspiration syndrome (Disease Ontology:DOID:11049); hydronephrosis (Disease Ontology:DOID:11111); IgA vasculitis (Disease Ontology:DOID:11123); disseminated intravascular coagulation (Disease Ontology:DOID:11247); adult respiratory distress syndrome (Disease Ontology:DOID:11394); pulmonary edema (Disease Ontology:DOID:11396); sciatic neuropathy (Disease Ontology:DOID:11446); prediabetes syndrome (Disease Ontology:DOID:11716); nephrotic syndrome (Disease Ontology:DOID:1184); Creutzfeldt-Jakob disease (Disease Ontology:DOID:11949); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); allergic disease (Disease Ontology:DOID:1205); otosclerosis (Disease Ontology:DOID:12185); primary biliary cholangitis (Disease Ontology:DOID:12236); alcoholic hepatitis (Disease Ontology:DOID:12351); dilated cardiomyopathy (Disease Ontology:DOID:12930); retinopathy of prematurity (Disease Ontology:DOID:13025); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); uveitis (Disease Ontology:DOID:13141); alpha 1-antitrypsin deficiency (Disease Ontology:DOID:13372); sick sinus syndrome (Disease Ontology:DOID:13884); toxic shock syndrome (Disease Ontology:DOID:14115); Fabry disease (Disease Ontology:DOID:14499); cystic fibrosis (Disease Ontology:DOID:1485); diffuse scleroderma (Disease Ontology:DOID:1580); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); impotence (Disease Ontology:DOID:1875); atherosclerosis (Disease Ontology:DOID:1936); hyperinsulinism (Disease Ontology:DOID:2018); transient cerebral ischemia (Disease Ontology:DOID:224); arteriosclerosis (Disease Ontology:DOID:2349); multiple sclerosis (Disease Ontology:DOID:2377); central retinal vein occlusion (Disease Ontology:DOID:2450); endometriosis (Disease Ontology:DOID:289); acute pancreatitis (Disease Ontology:DOID:2913); glomerulonephritis (Disease Ontology:DOID:2921); severe acute respiratory syndrome (Disease Ontology:DOID:2945); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328); coronary artery disease (Disease Ontology:DOID:3393); carotid artery disease (Disease Ontology:DOID:3407); middle cerebral artery infarction (Disease Ontology:DOID:3525); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); antithrombin III deficiency (Disease Ontology:DOID:3755); pulmonary fibrosis (Disease Ontology:DOID:3770); lung adenocarcinoma (Disease Ontology:DOID:3910); liver disease (Disease Ontology:DOID:409); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); cerebrovascular disease (Disease Ontology:DOID:6713); osteoarthritis (Disease Ontology:DOID:8398); chronic myeloid leukemia (Disease Ontology:DOID:8552); vasculitis (Disease Ontology:DOID:865); intermediate coronary syndrome (Disease Ontology:DOID:8805); skin melanoma (Disease Ontology:DOID:8923); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352); pulmonary emphysema (Disease Ontology:DOID:9675); mitral valve prolapse (Disease Ontology:DOID:988); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dme:Dmel_CG6717);  (R-DME-114608);  (R-DME-194002);  (R-DME-2022377);  (R-DME-204005);  (R-DME-381426);  (R-DME-5694530);  (R-DME-6798695);  (R-DME-8957275);  (R-DME-9757110);  (R-DME-9769739)",
        "pathway_count": 11,
        "publication_count": 11,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0007320 insemination;GO:0045861 negative regulation of proteolysis",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VLZ8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VM37-1",
        "uniprot_id": [
            {
                "id": "Q9VM37_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VM37",
                "type": "external"
            }
        ],
        "mass": 66791.0,
        "length": 580,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "Dmel\\CG4496",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285707",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285707",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG4496; CG4496; Dmel_CG4496",
        "gene_names_refseq": "CG4496; Dmel\\CG4496",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "CG4496-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG4496)",
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        "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0040029 epigenetic regulation of gene expression",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
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        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VM69-1",
        "uniprot_id": [
            {
                "id": "Q9VM69_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VM69",
                "type": "external"
            }
        ],
        "mass": 57171.0,
        "length": 511,
        "protein_name": "Nucleolar protein 58",
        "gene_name": "nop5",
        "organism": "Fruit fly",
        "refseq_name": "nop5",
        "refseq_ac": [
            {
                "id": "NP_477412",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477412",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nop5; 30; CG10206; DNOP5; Dmel\\CG10206; Dmel_CG10206; Dnop5; NOP5; Nop5",
        "gene_names_refseq": "2/30; CG10206; DNOP5; Dmel\\CG10206; Dnop5; NOP5; Nop5; nop5",
        "protein_names_uniprotkb": "Nucleolar protein 58; Nucleolar protein 5",
        "protein_names_refseq": "CG10206-PA; nop5-PA; nop5",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG10206);  (R-DME-4570464);  (R-DME-6791226)",
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        "class_list": "",
        "function": "Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs)., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0030515 snoRNA binding",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0031428 box C/D methylation guide snoRNP complex;GO:0032040 small-subunit processome",
        "go_biological_process": "GO:0006364 rRNA processing;GO:0000451 rRNA 2'-O-methylation;GO:0000452 snoRNA guided rRNA 2'-O-methylation",
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    },
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        "uniprot_canonical_ac": "Q9VMB6-1",
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            {
                "id": "Q9VMB6_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VMB6",
                "type": "external"
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        ],
        "mass": 51324.0,
        "length": 458,
        "protein_name": "Equilibrative nucleoside transporter 2, isoform A; Equilibrative nucleoside transporter 2, isoform B",
        "gene_name": "Ent2",
        "organism": "Fruit fly",
        "refseq_name": "equilibrative nucleoside transporter 2, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285680",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285680",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Ent2; BEST:LD04971; CG11045; CG31911; DmENT2; DmEnt2; Dmel\\CG31911; Dmel_CG31911; ENT2; LD04971; P124; ent2",
        "gene_names_refseq": "BEST:LD04971; CG11045; CG31911; DmENT2; DmEnt2; Dmel\\CG31911; ENT2; Ent2; LD04971; P124; ent2",
        "protein_names_uniprotkb": "Equilibrative nucleoside transporter 2, isoform A; Equilibrative nucleoside transporter 2, isoform B",
        "protein_names_refseq": "CG31911-PB; Ent2-PB; P124; equilibrative nucleoside transporter 2, isoform B; equilibrative nucleoside transporter 2",
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        "pathway": " (dme:Dmel_CG31911)",
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    },
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        ],
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        "protein_name": "glutaryl-CoA dehydrogenase (ETF)",
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        "organism": "Fruit fly",
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            {
                "id": "NP_609040",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609040",
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            }
        ],
        "gene_names_uniprotkb": "152078_at; CG9547; Dmel\\CG9547; Dmel_CG9547",
        "gene_names_refseq": "152078_at; CG9547; Dmel\\CG9547",
        "protein_names_uniprotkb": "glutaryl-CoA dehydrogenase (ETF); 1.3.8.6",
        "protein_names_refseq": "CG9547-PA; uncharacterized protein",
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        "disease": "glutaric acidemia I (Disease Ontology:DOID:0111254)",
        "pathway": " (dme:Dmel_CG9547);  (R-DME-71064)",
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                "id": "1.3.8.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.6",
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            }
        ],
        "go_molecular_function": "GO:0004361 glutaryl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0000062 fatty-acyl-CoA binding",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix",
        "go_biological_process": "GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046949 fatty-acyl-CoA biosynthetic process;GO:0033514 L-lysine catabolic process to acetyl-CoA via L-pipecolate",
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        ],
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        "length": 450,
        "protein_name": "Transmembrane protein 115",
        "gene_name": "Dmel\\CG9536",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001188706",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188706",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG9536; CG9536; Dmel_CG9536",
        "gene_names_refseq": "CG9536; Dmel\\CG9536",
        "protein_names_uniprotkb": "Transmembrane protein 115",
        "protein_names_refseq": "CG9536-PB; uncharacterized protein, isoform B",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG9536);  (R-DME-6807878)",
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        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane",
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        ],
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        "protein_name": "Ring finger and CHY zinc finger domain containing 1, isoform A; Ring finger and CHY zinc finger domain containing 1, isoform B",
        "gene_name": "Rchy1",
        "organism": "Fruit fly",
        "refseq_name": "ring finger and CHY zinc finger domain containing 1, isoform B",
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            {
                "id": "NP_001260133",
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        ],
        "gene_names_uniprotkb": "Rchy1; CG16947; Dmel\\CG16947; Dmel_CG16947; anon-EST:Posey20",
        "gene_names_refseq": "CG16947; Dmel\\CG16947; Rchy1; anon-EST:Posey20",
        "protein_names_uniprotkb": "Ring finger and CHY zinc finger domain containing 1, isoform A; Ring finger and CHY zinc finger domain containing 1, isoform B",
        "protein_names_refseq": "CG16947-PB; Rchy1-PB; ring finger and CHY zinc finger domain containing 1, isoform B",
        "tax_id": 7227,
        "disease": "sciatic neuropathy (Disease Ontology:DOID:11446)",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity",
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        "gene_names_refseq": "CG2185; Dmel\\CG2185; elm",
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            {
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        "function": "Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production., [UniProtKB, UniProtKB]",
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        "protein_name": "Delta-1-pyrroline-5-carboxylate synthase",
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            {
                "id": "NP_001246877",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246877",
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        "disease": "autosomal dominant cutis laxa 3 (Disease Ontology:DOID:0070131); autosomal recessive cutis laxa type IIIA (Disease Ontology:DOID:0070132); autosomal recessive cutis laxa type III (Disease Ontology:DOID:0070143); hereditary spastic paraplegia 9A (Disease Ontology:DOID:0110824); hereditary spastic paraplegia 9B (Disease Ontology:DOID:0110825); enterocele (Disease Ontology:DOID:1283); hereditary spastic paraplegia (Disease Ontology:DOID:2476); cataract (Disease Ontology:DOID:83); amino acid metabolic disorder (Disease Ontology:DOID:9252)",
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                "id": "2.7.2.11",
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        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0097268 cytoophidium",
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        "protein_name": "DUF4794 domain-containing protein",
        "gene_name": "Dmel\\CG14572",
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        "refseq_name": "uncharacterized protein",
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        ],
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        "protein_name": "Peroxisomal membrane protein PEX14",
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            {
                "id": "NP_649253",
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        "protein_names_uniprotkb": "Peroxisomal membrane protein PEX14; Peroxin-14",
        "protein_names_refseq": "CG4289-PA; Pex14-PA; peroxin 14",
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        "disease": "peroxisome biogenesis disorder 13A (Disease Ontology:DOID:0080487)",
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        "class_list": "",
        "function": "Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix. Plays a key role for peroxisome movement through a direct interaction with tubulin., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:1990429 peroxisomal importomer complex;GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0012505 endomembrane system",
        "go_biological_process": "GO:0016561 protein import into peroxisome matrix, translocation;GO:0016558 protein import into peroxisome matrix;GO:0016560 protein import into peroxisome matrix, docking",
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        ],
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        "protein_name": "CTBP-interacting protein, isoform A",
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        "refseq_name": "CTBP-interacting protein, isoform A",
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                "id": "NP_649224",
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        "protein_names_uniprotkb": "CTBP-interacting protein, isoform A",
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            {
                "id": "1.3.1.20",
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            },
            {
                "id": "1.1.1.179",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.179",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0000166 nucleotide binding;GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0042843 D-xylose catabolic process",
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    },
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            {
                "id": "Q9VQC0_DROME",
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            }
        ],
        "mass": 68853.0,
        "length": 632,
        "protein_name": "Vesicular glutamate transporter, isoform A; Vesicular glutamate transporter, isoform B",
        "gene_name": "VGlut1",
        "organism": "Fruit fly",
        "refseq_name": "vesicular glutamate transporter, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001245848",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245848",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "VGlut1; CG9887; DV-Glut; DVGLUT; DVGluT; DVGlut; Dmel\\CG9887; Dmel_CG9887; DvGluT; DvGlut; MFS11; VGLUT; VGluT; VGlut; Vglut; dVGLUT; dVGlut; dvGluT; dvGlut; dvglut; vGLUT; vGluT; vGlut; vglut",
        "gene_names_refseq": "CG9887; DV-Glut; DVGLUT; DVGluT; DVGlut; Dmel\\CG9887; DvGluT; DvGlut; MFS11; VGLUT; VGluT; VGlut; Vglut; dVGLUT; dVGlut; dvGluT; dvGlut; dvglut; vGLUT; vGluT; vGlut; vglut",
        "protein_names_uniprotkb": "Vesicular glutamate transporter, isoform A; Vesicular glutamate transporter, isoform B",
        "protein_names_refseq": "CG9887-PB; VGlut-PB; drosophila vesicular glutamate transporter; vesicular glutamate transporter, isoform B; vesicular glutamate transporter",
        "tax_id": 7227,
        "disease": "Parkinsonism (Disease Ontology:DOID:0080855); autosomal dominant nonsyndromic deafness 25 (Disease Ontology:DOID:0110555); sciatic neuropathy (Disease Ontology:DOID:11446); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); transient cerebral ischemia (Disease Ontology:DOID:224); cochlear disease (Disease Ontology:DOID:5463); trichinosis (Disease Ontology:DOID:9784)",
        "pathway": " (dme:Dmel_CG9887);  (R-DME-210500);  (R-DME-442660)",
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        "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0005313 L-glutamate transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0031982 vesicle;GO:0030672 synaptic vesicle membrane;GO:0008021 synaptic vesicle;GO:0060076 excitatory synapse",
        "go_biological_process": "GO:0050803 regulation of synapse structure or activity;GO:0035249 synaptic transmission, glutamatergic;GO:0006812 monoatomic cation transport;GO:0030641 regulation of cellular pH;GO:0098700 neurotransmitter loading into synaptic vesicle",
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        ],
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        "protein_name": "N-acetylgalactosaminide beta-1,3-galactosyltransferase",
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        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_608719",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608719",
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            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG2975; CG2975; Dmel_CG2975; dC1GalT4",
        "gene_names_refseq": "CG2975; Dmel\\CG2975; dC1GalT4",
        "protein_names_uniprotkb": "N-acetylgalactosaminide beta-1,3-galactosyltransferase; 2.4.1.122",
        "protein_names_refseq": "CG2975-PA; uncharacterized protein",
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        "class_list": "glycogene;glycosyltransferase",
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        ],
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        "protein_name": "RING-CH-type domain-containing protein",
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        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein, isoform B",
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            {
                "id": "NP_608725",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608725",
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        ],
        "gene_names_uniprotkb": "CT42388; CG2991; CT10107; Dmel\\CG2991; Dmel_CG2991",
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        "protein_names_refseq": "CG2991-PB; uncharacterized protein, isoform B",
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        ],
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        "protein_name": "Interferon-related developmental regulator 1",
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        "refseq_name": "Interferon-related developmental regulator 1",
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            {
                "id": "NP_722858",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_722858",
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        ],
        "gene_names_uniprotkb": "Ifrd1; CG15401; CG3098; CG31694; Dmel\\CG31694; Dmel_CG31694; difrd1",
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        "protein_names_uniprotkb": "Interferon-related developmental regulator 1",
        "protein_names_refseq": "CG31694-PA; Ifrd1-PA; Interferon-related developmental regulator 1",
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        ],
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        "protein_name": "NADH dehydrogenase [ubiquinone] 1 subunit C2",
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        "refseq_name": "NADH dehydrogenase (ubiquinone) B14.5 B subunit, isoform B",
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            {
                "id": "NP_001259991",
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        "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 subunit C2",
        "protein_names_refseq": "CG12400-PB; NADH dehydrogenase (ubiquinone) B14.5 B subunit, isoform B; NADH ubiquinone oxidoreductase B14.5B; NADH-ubiquinone oxidoreductase subunit B14.5b; NADH:ubiquinone oxidoreductase B14.5B subunit; ND-B14.5B-PB",
        "tax_id": 7227,
        "disease": "stroke (Disease Ontology:DOID:0051061); nuclear type mitochondrial complex I deficiency (Disease Ontology:DOID:0112065)",
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        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I",
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        ],
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        "protein_name": "Uncharacterized protein",
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        "refseq_name": "uncharacterized protein",
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                "id": "NP_608769",
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        ],
        "gene_names_uniprotkb": "anon-WO0140519.135; CG8838; Dmel\\CG8838; Dmel_CG8838",
        "gene_names_refseq": "CG8838; Dmel\\CG8838; anon-WO0140519.135",
        "protein_names_uniprotkb": "Uncharacterized protein",
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        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004252 serine-type endopeptidase activity",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0006508 proteolysis",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VRD1-1",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VRF6-1",
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            {
                "id": "Q9VRF6_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VRF6",
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            }
        ],
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        "length": 185,
        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG1724",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_608439",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608439",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG1724; BcDNA:AT13347; CG1724; Dmel_CG1724",
        "gene_names_refseq": "BcDNA:AT13347; CG1724; Dmel\\CG1724",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG1724-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG1724);  (R-DME-1268020)",
        "pathway_count": 2,
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        "class_list": "",
        "function": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005744 TIM23 mitochondrial import inner membrane translocase complex",
        "go_biological_process": "GO:0010954 positive regulation of protein processing;GO:0030150 protein import into mitochondrial matrix",
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        "kg_view_protein": true
    },
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            {
                "id": "Q9VRI0_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VRI0",
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            }
        ],
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        "length": 560,
        "protein_name": "Probable ATP-dependent RNA helicase DDX56",
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        "organism": "Fruit fly",
        "refseq_name": "DEAD-box helicase 56, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285517",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285517",
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            }
        ],
        "gene_names_uniprotkb": "Ddx56; 11P1; 14; 7; A112; CG1666; DmRH10; Dmel\\CG1666; Dmel_CG1666; HLC; HM-44; Hlc; dDDX56; hlc; l(1)11P1; l(1)19Ff; l(1)8-1; l(1)A112; l(1)S-19F6; l11P1; lA112",
        "gene_names_refseq": "11P1; 14; 7; A112; CG1666; Ddx56; DmRH10; Dmel\\CG1666; HLC; HM-44; Hlc; dDDX56; hlc; l(1)11P1; l(1)19Ff; l(1)8-1; l(1)A112; l(1)S-19F6; l11P1; lA112",
        "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX56; 3.6.4.13; DEAD box protein 56",
        "protein_names_refseq": "CG1666-PB; DEAD-box helicase 56, isoform B; Ddx56-PB; RNA helicase gene; lethal(1)19Ff; section 14; section 7",
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        "class_list": "",
        "function": "Nucleolar RNA helicase that plays a role in various biological processes including innate immunity, ribosome biogenesis or nucleolus organization. Plays an essential role in maintaining nucleolar integrity in planarian stem cells. Maintains embryonic stem cells proliferation by conventional regulation of ribosome assembly and interaction with OCT4 and POU5F1 complex. Regulates antiviral innate immunity by inhibiting the virus-triggered signaling nuclear translocation of IRF3. Mechanistically, acts by disrupting the interaction between IRF3 and importin IPO5. May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity., [UniProtKB, UniProtKB]",
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            {
                "id": "7.2.2.-",
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            {
                "id": "3.6.4.-",
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            {
                "id": "3.6.4.10",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
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                "id": "3.1.-.-",
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                "id": "3.6.1.15",
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                "id": "3.-.-.-",
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        "go_biological_process": "GO:0051607 defense response to virus;GO:0006364 rRNA processing;GO:0044830 host-mediated perturbation of viral RNA genome replication",
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            {
                "id": "NP_647946",
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                "id": "1.-.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-",
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                "id": "NP_001261482",
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        ],
        "gene_names_uniprotkb": "Dhpr; CG4665; DHPR; Dmel\\CG4665; Dmel_CG4665",
        "gene_names_refseq": "CG4665; DHPR; Dhpr; Dmel\\CG4665",
        "protein_names_uniprotkb": "Dihydropteridine reductase; 1.5.1.34; HDHPR; Quinoid dihydropteridine reductase",
        "protein_names_refseq": "CG4665-PB; Dhpr-PB; dihydropteridine reductase, isoform B",
        "tax_id": 7227,
        "disease": "BH4-deficient hyperphenylalaninemia C (Disease Ontology:DOID:0081130); hypertension (Disease Ontology:DOID:10763); status epilepticus (Disease Ontology:DOID:1824); phenylketonuria (Disease Ontology:DOID:9281)",
        "pathway": " (dme:Dmel_CG4665);  (R-DME-8964208)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 4,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.5.1.34",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.34",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0070402 NADPH binding;GO:0004155 6,7-dihydropteridine reductase activity;GO:0070404 NADH binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006559 L-phenylalanine catabolic process;GO:0006729 tetrahydrobiopterin biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VSU6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VSV1-1",
        "uniprot_id": [
            {
                "id": "Q9VSV1_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VSV1",
                "type": "external"
            }
        ],
        "mass": 66058.0,
        "length": 599,
        "protein_name": "Solute carrier family 45 member 1, isoform A; Solute carrier family 45 member 1, isoform B; Solute carrier family 45 member 1, isoform C; Solute carrier family 45 member 1, isoform D",
        "gene_name": "Slc45-1",
        "organism": "Fruit fly",
        "refseq_name": "solute carrier family 45 member 1, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001261618",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261618",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Slc45-1; CG4484; Dmel\\CG4484; Dmel_CG4484; scrt",
        "gene_names_refseq": "CG4484; Dmel\\CG4484; Slc45-1; scrt",
        "protein_names_uniprotkb": "Solute carrier family 45 member 1, isoform A; Solute carrier family 45 member 1, isoform B; Solute carrier family 45 member 1, isoform C; Solute carrier family 45 member 1, isoform D",
        "protein_names_refseq": "CG4484-PB; Slc45 ortholog 1; Slc45-1-PB; solute carrier family 45 member 1, isoform B; sucrose transporter",
        "tax_id": 7227,
        "disease": "oculocutaneous albinism (Disease Ontology:DOID:0050632); oculocutaneous albinism type IV (Disease Ontology:DOID:0070098); pigmentation disease (Disease Ontology:DOID:10123); cataract (Disease Ontology:DOID:83)",
        "pathway": " (dme:Dmel_CG4484)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 4,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008506 sucrose:proton symporter activity;GO:0008515 sucrose transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0045177 apical part of cell;GO:0031410 cytoplasmic vesicle",
        "go_biological_process": "GO:0015770 sucrose transport",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VSV1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VSV2-1",
        "uniprot_id": [
            {
                "id": "Q9VSV2_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VSV2",
                "type": "external"
            }
        ],
        "mass": 69779.0,
        "length": 629,
        "protein_name": "Transporter",
        "gene_name": "DmNAT3",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_648293",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648293",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "DmNAT3; CG4476; Dmel\\CG4476; Dmel_CG4476; anon-WO0149848.7",
        "gene_names_refseq": "CG4476; DmNAT3; Dmel\\CG4476; anon-WO0149848.7",
        "protein_names_uniprotkb": "Transporter",
        "protein_names_refseq": "CG4476-PB; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG4476);  (R-DME-352230);  (R-DME-442660)",
        "pathway_count": 3,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015179 L-amino acid transmembrane transporter activity;GO:0046872 metal ion binding;GO:0005283 amino acid:sodium symporter activity;GO:0005416 amino acid:monoatomic cation symporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane",
        "go_biological_process": "GO:0035725 sodium ion transmembrane transport;GO:0003333 amino acid transmembrane transport;GO:0007632 visual behavior;GO:0006836 neurotransmitter transport;GO:1903804 glycine import across plasma membrane",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VSV2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VSW4-1",
        "uniprot_id": [
            {
                "id": "Q9VSW4_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VSW4",
                "type": "external"
            }
        ],
        "mass": 28485.0,
        "length": 254,
        "protein_name": "Ribosome-recycling factor, mitochondrial",
        "gene_name": "mRRF1",
        "organism": "Fruit fly",
        "refseq_name": "mitochondrial ribosome recycling factor 1",
        "refseq_ac": [
            {
                "id": "NP_648302",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648302",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mRRF1; CG4447; Dmel\\CG4447; Dmel_CG4447",
        "gene_names_refseq": "CG4447; Dmel\\CG4447; mRRF1",
        "protein_names_uniprotkb": "Ribosome-recycling factor, mitochondrial; Ribosome-releasing factor, mitochondrial",
        "protein_names_refseq": "CG4447-PA; mRRF1-PA; mitochondrial ribosome recycling factor 1",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG4447);  (R-DME-5419276)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0043023 ribosomal large subunit binding",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix",
        "go_biological_process": "GO:0032790 ribosome disassembly;GO:0006412 translation;GO:0032543 mitochondrial translation",
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        "hit_score": 1.2,
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VSX2-1",
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            {
                "id": "Q9VSX2_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VSX2",
                "type": "external"
            }
        ],
        "mass": 23778.0,
        "length": 200,
        "protein_name": "SHSP domain-containing protein",
        "gene_name": "BEST:GH12586",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_648304",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648304",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "BEST:GH12586; 148460_at; 4461; CG4461; DmCG4461; Dmel23.8; Dmel\\CG4461; Dmel_CG4461; Hsp20; gh12586",
        "gene_names_refseq": "148460_at; 4461; BEST:GH12586; CG4461; DmCG4461; Dmel23.8; Dmel\\CG4461; Hsp20; gh12586",
        "protein_names_uniprotkb": "SHSP domain-containing protein",
        "protein_names_refseq": "CG4461-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "adult-onset myofibrillar myopathy 2A (Disease Ontology:DOID:0080093); infantile-onset myofibrillar myopathy-2B (Disease Ontology:DOID:0080309); Charcot-Marie-Tooth disease axonal type 2F (Disease Ontology:DOID:0110163); cataract 16 multiple types (Disease Ontology:DOID:0110250); cataract 9 multiple types (Disease Ontology:DOID:0110266); dilated cardiomyopathy 1II (Disease Ontology:DOID:0110450); autosomal dominant distal hereditary motor neuronopathy 3 (Disease Ontology:DOID:0111207); Alzheimer's disease (Disease Ontology:DOID:10652); sarcoma (Disease Ontology:DOID:1115); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); pancreatic cancer (Disease Ontology:DOID:1793); transient cerebral ischemia (Disease Ontology:DOID:224); macular degeneration (Disease Ontology:DOID:4448); rheumatoid arthritis (Disease Ontology:DOID:7148); cataract (Disease Ontology:DOID:83); ocular hypertension (Disease Ontology:DOID:9282); galactosemia (Disease Ontology:DOID:9870)",
        "pathway": " (dme:Dmel_CG4461);  (R-DME-3371571)",
        "pathway_count": 2,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
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        "biomarker_type": "",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0051082 unfolded protein binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006457 protein folding;GO:0009408 response to heat;GO:0042026 protein refolding",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VSX2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VT00-1",
        "uniprot_id": [
            {
                "id": "JARD2_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VT00",
                "type": "external"
            }
        ],
        "mass": 252525.0,
        "length": 2351,
        "protein_name": "Jumonji, AT rich interactive domain protein 2",
        "gene_name": "Jarid2",
        "organism": "Fruit fly",
        "refseq_name": "Jumonji, AT rich interactive domain 2",
        "refseq_ac": [
            {
                "id": "NP_648324",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648324",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Jarid2; CG3654; Jmj",
        "gene_names_refseq": "CG3654; Dmel\\CG3654; JARID2; Jarid2; dJARID2; dJmj; djmj; jarid2; l(3)j2B8",
        "protein_names_uniprotkb": "Jumonji, AT rich interactive domain protein 2; Protein jumonji; dJmj",
        "protein_names_refseq": "CG3654-PD; Jarid2-PD; Jumonji, AT rich interactive domain 2; Jumonji, AT-rich interactive domain 2; jumonji",
        "tax_id": 7227,
        "disease": "autistic disorder (Disease Ontology:DOID:12849); aortic valve stenosis (Disease Ontology:DOID:1712)",
        "pathway": " (dme:Dmel_CG3654);  (R-DME-212300)",
        "pathway_count": 2,
        "publication_count": 9,
        "publication_id_list": "10731132;12537569;12537572;17970746;22354997;25620564;28701701;33925313;40245499",
        "class_list": "",
        "function": "Regulator of histone methyltransferase complexes (By similarity). Involved in the establishment or maintenance of higher order chromosome compaction and closed euchromatin structure (PubMed:17970746). Accessory component of the polycomb repressive complex 2 (PRC2) involved in maintenance of transcriptional repression and regulation of transcriptional activation or elongation; functions in a PRC2-dependent and PRC2-independent manner (PubMed:22354997). Reduces levels of H3K27me3 histone modification (PubMed:22354997)., [UniProtKB, UniProtKB, PubMed, PubMed]",
        "predicted_glycosites": 5,
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                "id": "NP_648452",
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        "tax_id": 7227,
        "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); autism spectrum disorder (Disease Ontology:DOID:0060041); chromosome 15q11.2 deletion syndrome (Disease Ontology:DOID:0060393); intellectual disability (Disease Ontology:DOID:1059); epilepsy (Disease Ontology:DOID:1826); Angelman syndrome (Disease Ontology:DOID:1932)",
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                "id": "2.3.2.23",
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                "id": "2.3.2.31",
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                "id": "NP_001287032",
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                "id": "NP_729728",
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                "id": "3.6.1.15",
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                "id": "3.-.-.-",
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        "function": "Involved in spliceosome assembly., [UniProtKB, UniProtKB]; Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0015030 Cajal body",
        "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0006265 DNA topological change;GO:0141194 siRNA-mediated heterochromatin formation",
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    },
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            {
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            }
        ],
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        "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum",
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            }
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        ],
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        "protein_name": "Inositol-1-monophosphatase",
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        "protein_names_uniprotkb": "Inositol-1-monophosphatase; 3.1.3.25",
        "protein_names_refseq": "CG17028-PB; uncharacterized protein, isoform B",
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        "disease": "autosomal recessive intellectual developmental disorder 59 (Disease Ontology:DOID:0081221); intellectual disability (Disease Ontology:DOID:1059); bipolar disorder (Disease Ontology:DOID:3312); schizophrenia (Disease Ontology:DOID:5419)",
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        "go_biological_process": "GO:0006020 inositol metabolic process;GO:0007165 signal transduction;GO:0006021 inositol biosynthetic process;GO:0046854 phosphatidylinositol phosphate biosynthetic process",
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        ],
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        "length": 133,
        "protein_name": "Programmed cell death 5",
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        "organism": "Fruit fly",
        "refseq_name": "programmed cell death 5",
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                "id": "NP_648848",
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        "gene_names_refseq": "BcDNA:RE17056; CG13072; DMPDCD-5; Dmel\\CG13072; PDCD-5; PDCD5",
        "protein_names_uniprotkb": "Programmed cell death 5",
        "protein_names_refseq": "CG13072-PA; PDCD-5-PA; programmed cell death 5; programmed cell death gene-5",
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        "protein_names_uniprotkb": "ABC transporter domain-containing protein",
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        "disease": "neonatal respiratory failure (Disease Ontology:DOID:11161); respiratory failure (Disease Ontology:DOID:11162); pulmonary alveolar proteinosis (Disease Ontology:DOID:12120); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); interstitial lung disease (Disease Ontology:DOID:3082); lung disease (Disease Ontology:DOID:850)",
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        "protein_names_uniprotkb": "Uncharacterized protein",
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        ],
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            {
                "id": "NP_573150",
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            }
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            {
                "id": "Q9VXF6_DROME",
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        ],
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            {
                "id": "NP_573131",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573131",
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            }
        ],
        "gene_names_uniprotkb": "Cnx14D; CG9906; Cnx; Dmel\\CG9906; Dmel_CG9906; Xcbp1; cnx14D",
        "gene_names_refseq": "CG9906; Cnx14D; Cnx; Dmel\\CG9906; Xcbp1; cnx14D",
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        "function": "Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death., [UniProtKB, UniProtKB]",
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        ],
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            {
                "id": "NP_001285328",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285328",
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            }
        ],
        "gene_names_uniprotkb": "rngo; CG4420; Ddi1; Dmel\\CG4420; Dmel_CG4420; Rngo",
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        "protein_names_uniprotkb": "3.4.23.-; Rings lost, isoform A; Rings lost, isoform B",
        "protein_names_refseq": "CG4420-PB; rings lost, isoform B; rngo-PB",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol",
        "go_biological_process": "GO:0006508 proteolysis;GO:0015031 protein transport;GO:0007301 female germline ring canal formation",
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    },
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        ],
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            {
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        "protein_names_uniprotkb": "27 kDa hemolymph protein",
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        ],
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        "protein_name": "Disco-related, isoform A; Disco-related, isoform B; Disco-related, isoform C; Disco-related, isoform D",
        "gene_name": "disco-r",
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        "refseq_name": "disco-related, isoform B",
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            {
                "id": "NP_001259598",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259598",
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            }
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        "gene_names_uniprotkb": "disco-r; CG32577; CG9219; CG9223; Dmel\\CG32577; Dmel_CG32577; bae",
        "gene_names_refseq": "CG32577; CG9219; CG9223; Dmel\\CG32577; bae; disco-r",
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        "protein_names_refseq": "CG32577-PB; baetone; batone; disco-r-PB; disco-related, isoform B; disconnected-related; discorelated",
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        "disease": "primary ovarian insufficiency 16 (Disease Ontology:DOID:0080873)",
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        ],
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        "protein_name": "Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial",
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        "refseq_name": "NADH dehydrogenase (ubiquinone) 20 kDa subunit, isoform C",
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                "id": "NP_001285313",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285313",
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        "gene_names_refseq": "20 kDa; CG9172; Dmel\\CG9172; Dmel_CG9172; ND-20; ND20; NDUFS7; NUKM; PSST; dNDUFS7A; dNDUFS7",
        "protein_names_uniprotkb": "Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial",
        "protein_names_refseq": "CG9172-PC; FBpp0073949; NADH dehydrogenase (ubiquinone) 20 kDa subunit, isoform C; NADH ubiquinone oxidoreductase 20 kDa; NADH-UBIQUINONE OXIDOREDUCTASE 20 KDA SUBUNIT; NADH:ubiquinone oxidoreductase 20 kDa subunit; ND-20-PC",
        "tax_id": 7227,
        "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); mitochondrial complex I deficiency (Disease Ontology:DOID:0060536); nuclear type mitochondrial complex I deficiency 3 (Disease Ontology:DOID:0112093); bipolar disorder (Disease Ontology:DOID:3312)",
        "pathway": " (dme:Dmel_CG9172);  (R-DME-611105);  (R-DME-6799198)",
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        "biomarker_type": "",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0022857 transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0055085 transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VYV0-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VYW3-1",
        "uniprot_id": [
            {
                "id": "Q9VYW3_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VYW3",
                "type": "external"
            }
        ],
        "mass": 11963.0,
        "length": 112,
        "protein_name": "Replication protein A3, isoform A; Replication protein A3, isoform B",
        "gene_name": "RPA3",
        "organism": "Fruit fly",
        "refseq_name": "replication protein A3, isoform B",
        "refseq_ac": [
            {
                "id": "NP_001285131",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285131",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "RPA3; BcDNA:RH55360; CG15220; D-SSB; DRP-A; DmRPA; Dmel\\CG15220; Dmel_CG15220; RP-A; RPA; RpA-8; Ssb-8; dRP-A; l(1)G0241",
        "gene_names_refseq": "BcDNA:RH55360; CG15220; D-SSB; DRP-A; DmRPA; Dmel\\CG15220; RP-A; RPA3; RPA; RpA-8; Ssb-8; dRP-A; l(1)G0241",
        "protein_names_uniprotkb": "Replication protein A3, isoform A; Replication protein A3, isoform B",
        "protein_names_refseq": "CG15220-PB; RPA3-PB; drosophila replication protein A; lethal (1) G0241; replication protein A 8; replication protein A3, isoform B; replication protein A; single stranded-binding protein 8",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG15220);  (R-DME-110312);  (R-DME-110314);  (R-DME-110320);  (R-DME-176187);  (R-DME-5651801);  (R-DME-5655862);  (R-DME-5656121);  (R-DME-5656169);  (R-DME-5696397);  (R-DME-5696400);  (R-DME-6782135);  (R-DME-6782210);  (R-DME-68962);  (R-DME-69166)",
        "pathway_count": 15,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0005662 DNA replication factor A complex",
        "go_biological_process": "GO:0006284 base-excision repair;GO:0006260 DNA replication;GO:0006298 mismatch repair;GO:0000724 double-strand break repair via homologous recombination;GO:0097150 neuronal stem cell population maintenance",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VYW3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ04-1",
        "uniprot_id": [
            {
                "id": "Q9VZ04_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ04",
                "type": "external"
            }
        ],
        "mass": 96149.0,
        "length": 849,
        "protein_name": "Mannosyl-oligosaccharide glucosidase",
        "gene_name": "GCS1",
        "organism": "Fruit fly",
        "refseq_name": "glucosidase 1, isoform C",
        "refseq_ac": [
            {
                "id": "NP_001245621",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245621",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "GCS1; CG1597; Dmel\\CG1597; Dmel_CG1597",
        "gene_names_refseq": "CG1597; Dmel\\CG1597; GCS1",
        "protein_names_uniprotkb": "Mannosyl-oligosaccharide glucosidase; 3.2.1.106",
        "protein_names_refseq": "CG1597-PC; GCS1-PC; glucosidase 1, isoform C",
        "tax_id": 7227,
        "disease": "congenital disorder of glycosylation type IIb (Disease Ontology:DOID:0070254)",
        "pathway": " (dme:Dmel_CG1597)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "glycogene;glycosylhydrolase",
        "function": "Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "3.2.1.106",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.106",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004573 Glc3Man9GlcNAc2 oligosaccharide glucosidase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system",
        "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0009311 oligosaccharide metabolic process;GO:0140277 endoplasmic reticulum N-glycan trimming",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q9VZ04-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000100000000000.0000000001000.001.10100",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ12-1",
        "uniprot_id": [
            {
                "id": "Q9VZ12_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ12",
                "type": "external"
            }
        ],
        "mass": 12193.0,
        "length": 122,
        "protein_name": "Uncharacterized protein",
        "gene_name": "Dmel\\CG15198",
        "organism": "Fruit fly",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "NP_572701",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572701",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "Dmel\\CG15198; CG15198; Dmel_CG15198",
        "gene_names_refseq": "CG15198; Dmel\\CG15198",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "CG15198-PA; uncharacterized protein",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG15198)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
        "class_list": "",
        "function": "",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "Q9VZ12-1",
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        "filter_code": "0000000.0000101.100000.000000100000000000.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q9VZ21-1",
        "uniprot_id": [
            {
                "id": "RTRV_DROME",
                "url": "https://www.uniprot.org/uniprot/Q9VZ21",
                "type": "external"
            }
        ],
        "mass": 16843.0,
        "length": 151,
        "protein_name": "UPAR/Ly6 domain-containing protein rtv",
        "gene_name": "rtv",
        "organism": "Fruit fly",
        "refseq_name": "retroactive, isoform C",
        "refseq_ac": [
            {
                "id": "NP_001259443",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259443",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rtv; CG1397; l(1)L1",
        "gene_names_refseq": "1; CG1397; Dmel\\CG1397; L1; Rtv; l(1)10Ag; l(1)G13; l(1)L1; rtv",
        "protein_names_uniprotkb": "UPAR/Ly6 domain-containing protein rtv; Protein retroactive",
        "protein_names_refseq": "CG1397-PC; retroactive, isoform C; rtv-PC",
        "tax_id": 7227,
        "disease": "",
        "pathway": " (dme:Dmel_CG1397)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "10731132;12537569;12537572;15844167;16339194;18477586;19126864;19502482",
        "class_list": "",
        "function": "Required for chitin fiber assembly and organization involved in cuticle formation and tracheal development., [UniProtKB, PubMed, PubMed, PubMed]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "M9PJI2",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane",
        "go_biological_process": "GO:0042335 cuticle development;GO:0030431 sleep;GO:0032222 regulation of synaptic transmission, cholinergic;GO:0035152 regulation of tube architecture, open tracheal system;GO:0007424 open tracheal system development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
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        "record_type": "protein",
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    }
]
