[ { "uniprot_canonical_ac": "Q54B51-1", "uniprot_id": [ { "id": "PKS44_DICDI", "url": "https://www.uniprot.org/uniprot/Q54B51", "type": "external" } ], "mass": 348031.0, "length": 3078, "protein_name": "Probable polyketide synthase 44", "gene_name": "pks44", "organism": "Cellular slime mold", "refseq_name": "beta-ketoacyl synthase family protein", "refseq_ac": [ { "id": "XP_628865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628865", "type": "external" } ], "gene_names_uniprotkb": "pks44; DDB_G0293902", "gene_names_refseq": "pks44", "protein_names_uniprotkb": "Probable polyketide synthase 44; 2.3.1.-; dipks44", "protein_names_refseq": "beta-ketoacyl synthase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293902)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17660200", "class_list": "", "function": "Probable polyketide synthase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54B51-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54B59-1", "uniprot_id": [ { "id": "OMT12_DICDI", "url": "https://www.uniprot.org/uniprot/Q54B59", "type": "external" } ], "mass": 42586.0, "length": 369, "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "organism": "Cellular slime mold", "refseq_name": "O-methyltransferase family 2 protein", "refseq_ac": [ { "id": "XP_628929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628929", "type": "external" } ], "gene_names_uniprotkb": "omt12; DDB_G0293888", "gene_names_refseq": "omt12", "protein_names_uniprotkb": "O-methyltransferase 12; 2.1.1.-", "protein_names_refseq": "O-methyltransferase family 2 protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293888)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12796308;15470253;15470642;15875012;18252726;18590548", "class_list": "", "function": "S-adenosyl-L-methionine dependent O-methyltransferase that may be involved in modifying resorcinol ring to synthesize a variant of 4-methyl-5-pentylbenzene-1,3-diol., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0008168 methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0008171 O-methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54B59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54B65-1", "uniprot_id": [ { "id": "SF3A2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54B65", "type": "external" } ], "mass": 25071.0, "length": 215, "protein_name": "Splicing factor 3A subunit 2", "gene_name": "sf3a2", "organism": "Cellular slime mold", "refseq_name": "U1-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_628923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628923", "type": "external" } ], "gene_names_uniprotkb": "sf3a2; DDB_G0293876", "gene_names_refseq": "sf3a2", "protein_names_uniprotkb": "Splicing factor 3A subunit 2", "protein_names_refseq": "U1-type zinc finger-containing protein; splicing factor 3A subunit 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293876); (R-DDI-9770562); (R-DDI-9943411)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54B65-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54B67-1", "uniprot_id": [ { "id": "MCFZ_DICDI", "url": "https://www.uniprot.org/uniprot/Q54B67", "type": "external" } ], "mass": 33268.0, "length": 301, "protein_name": "Mitochondrial substrate carrier family protein Z", "gene_name": "mcfZ", "organism": "Cellular slime mold", "refseq_name": "mitochondrial substrate carrier family protein", "refseq_ac": [ { "id": "XP_628921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628921", "type": "external" } ], "gene_names_uniprotkb": "mcfZ; DDB_G0293874; mitA", "gene_names_refseq": "mcfZ", "protein_names_uniprotkb": "Mitochondrial substrate carrier family protein Z", "protein_names_refseq": "mitochondrial substrate carrier family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293874)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11553701;12796308;15875012;17442478", "class_list": "", "function": "Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005469 succinate:fumarate antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015744 succinate transport;GO:0015741 fumarate transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54B67-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54B68-1", "uniprot_id": [ { "id": "IDHB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54B68", "type": "external" } ], "mass": 38688.0, "length": 360, "protein_name": "Isocitrate dehydrogenase [NAD] regulatory subunit B, mitochondrial", "gene_name": "idhB", "organism": "Cellular slime mold", "refseq_name": "isocitrate dehydrogenase (NAD+)", "refseq_ac": [ { "id": "XP_628920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628920", "type": "external" } ], "gene_names_uniprotkb": "idhB; DDB_G0293872", "gene_names_refseq": "idhB", "protein_names_uniprotkb": "Isocitrate dehydrogenase [NAD] regulatory subunit B, mitochondrial; 1.1.1.41", "protein_names_refseq": "isocitrate dehydrogenase (NAD+) beta subunit; isocitrate dehydrogenase (NAD+)", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293872); (R-DDI-71403)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Performs an essential role in the oxidative function of the citric acid cycle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.41", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0051287 NAD binding;GO:0004449 isocitrate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54B68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54B82-1", "uniprot_id": [ { "id": "CSN4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54B82", "type": "external" } ], "mass": 45383.0, "length": 393, "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "csn4", "organism": "Cellular slime mold", "refseq_name": "COP9 signalosome complex subunit 4", "refseq_ac": [ { "id": "XP_628938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628938", "type": "external" } ], "gene_names_uniprotkb": "csn4; DDB_G0293844", "gene_names_refseq": "CSN4", "protein_names_uniprotkb": "COP9 signalosome complex subunit 4; Signalosome subunit 4", "protein_names_refseq": "COP9 signalosome complex subunit 4; proteasome component region PCI domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293844); (R-DDI-5696394); (R-DDI-6781823); (R-DDI-8856825); (R-DDI-8951664); (R-DDI-9013422)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "15875012;16781008", "class_list": "", "function": "Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2PQ75", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008180 COP9 signalosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54B82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BC6-1", "uniprot_id": [ { "id": "PSMD2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BC6", "type": "external" } ], "mass": 98366.0, "length": 893, "protein_name": "26S proteasome non-ATPase regulatory subunit 2", "gene_name": "psmD2", "organism": "Cellular slime mold", "refseq_name": "26S proteasome non-ATPase regulatory subunit 2", "refseq_ac": [ { "id": "XP_628968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628968", "type": "external" } ], "gene_names_uniprotkb": "psmD2; DDB_G0293752", "gene_names_refseq": "psmD2", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 2", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 2; 26S proteasome regulatory subunit S2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293752); (R-DDI-1236978); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-187577); (R-DDI-2467813); (R-DDI-349425); (R-DDI-382556); (R-DDI-450408); (R-DDI-4641258); (R-DDI-5632684); (R-DDI-5658442); (R-DDI-5687128); (R-DDI-5689603); (R-DDI-5689880); (R-DDI-6798695); (R-DDI-68949); (R-DDI-69017); (R-DDI-69601); (R-DDI-75815); (R-DDI-8854050); (R-DDI-8948751); (R-DDI-8951664); (R-DDI-9755511); (R-DDI-983168); (R-DDI-9907900); (R-DDI-9929491); (R-DDI-9954709)", "pathway_count": 29, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0008540 proteasome regulatory particle, base subcomplex;GO:0005634 nucleus;GO:0005764 lysosome;GO:0005776 autophagosome", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042176 regulation of protein catabolic process;GO:0006972 hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BC6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BC8-1", "uniprot_id": [ { "id": "PSB5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BC8", "type": "external" } ], "mass": 30280.0, "length": 272, "protein_name": "Proteasome subunit beta type-5", "gene_name": "psmB5", "organism": "Cellular slime mold", "refseq_name": "20S proteasome subunit beta-5", "refseq_ac": [ { "id": "XP_628966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628966", "type": "external" } ], "gene_names_uniprotkb": "psmB5; DDB_G0293784", "gene_names_refseq": "psmB5", "protein_names_uniprotkb": "Proteasome subunit beta type-5; 3.4.25.1", "protein_names_refseq": "20S proteasome subunit beta-5; proteasome subunit beta type 5", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293784); (R-DDI-1236974); (R-DDI-1236978); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-187577); (R-DDI-2467813); (R-DDI-349425); (R-DDI-382556); (R-DDI-450408); (R-DDI-4641258); (R-DDI-5632684); (R-DDI-5658442); (R-DDI-5687128); (R-DDI-5689603); (R-DDI-5689880); (R-DDI-68949); (R-DDI-69017); (R-DDI-69601); (R-DDI-75815); (R-DDI-8854050); (R-DDI-8948751); (R-DDI-8951664); (R-DDI-9755511); (R-DDI-983168); (R-DDI-9907900); (R-DDI-9912633); (R-DDI-9929491); (R-DDI-9954709)", "pathway_count": 30, "publication_count": 2, "publication_id_list": "15875012;8130037", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BC9-1", "uniprot_id": [ { "id": "DYRK2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BC9", "type": "external" } ], "mass": 98276.0, "length": 915, "protein_name": "Probable serine/threonine-protein kinase dyrk2", "gene_name": "dyrk2", "organism": "Cellular slime mold", "refseq_name": "DYRK family protein kinase", "refseq_ac": [ { "id": "XP_628965", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628965", "type": "external" } ], "gene_names_uniprotkb": "dyrk2; DDB_G0293750", "gene_names_refseq": "dyrk2", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase dyrk2; 2.7.12.1; Dual specificity tyrosine-phosphorylation-regulated kinase 2", "protein_names_refseq": "DYRK family protein kinase; protein kinase, CMGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293750); (R-DDI-6804756)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BD4-1", "uniprot_id": [ { "id": "STATC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BD4", "type": "external" } ], "mass": 107204.0, "length": 931, "protein_name": "Signal transducer and activator of transcription C", "gene_name": "dstC", "organism": "Cellular slime mold", "refseq_name": "signal transducer and activator of transcription family protein", "refseq_ac": [ { "id": "XP_629095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629095", "type": "external" } ], "gene_names_uniprotkb": "dstC; DDB_G0293532; statC", "gene_names_refseq": "dstC", "protein_names_uniprotkb": "Signal transducer and activator of transcription C; Dd-STATc; STAT5 homolog C", "protein_names_refseq": "signal transducer and activator of transcription family protein; transcriptional repressor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293532); (R-DDI-1059683); (R-DDI-1169408); (R-DDI-201556); (R-DDI-3249367); (R-DDI-6783783); (R-DDI-6785807); (R-DDI-877300); (R-DDI-877312); (R-DDI-8854691); (R-DDI-8983432); (R-DDI-8984722); (R-DDI-8985947); (R-DDI-9008059); (R-DDI-9020591); (R-DDI-9020933); (R-DDI-9020956); (R-DDI-909733); (R-DDI-9701898); (R-DDI-9833482); (R-DDI-9860927)", "pathway_count": 21, "publication_count": 4, "publication_id_list": "11336701;12506009;15875012;17517120", "class_list": "", "function": "Transcription factor that regulates gene expression during development. May play a role in regulating gene expression in response to osmotic stress., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9BLX2", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990782 protein tyrosine kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006952 defense response;GO:0006970 response to osmotic stress;GO:0006979 response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54BD4-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BD5-1", "uniprot_id": [ { "id": "TRM13_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BD5", "type": "external" } ], "mass": 61425.0, "length": 525, "protein_name": "tRNA:m(4)X modification enzyme TRM13 homolog", "gene_name": "trm13", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629094", "type": "external" } ], "gene_names_uniprotkb": "trm13; DDB_G0293682", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA:m(4)X modification enzyme TRM13 homolog; 2.1.1.225", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293682)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.225", "type": "external" } ], "go_molecular_function": "GO:0008175 tRNA methyltransferase activity;GO:0106050 tRNA 2'-O-methyltransferase activity;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BD6-1", "uniprot_id": [ { "id": "DDX51_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BD6", "type": "external" } ], "mass": 64642.0, "length": 563, "protein_name": "Probable ATP-dependent RNA helicase ddx51", "gene_name": "ddx51", "organism": "Cellular slime mold", "refseq_name": "DEAD/DEAH box helicase", "refseq_ac": [ { "id": "XP_629093", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629093", "type": "external" } ], "gene_names_uniprotkb": "ddx51; DDB_G0293740", "gene_names_refseq": "ddx51", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase ddx51; 3.6.4.13; DEAD box protein 51", "protein_names_refseq": "DEAD/DEAH box helicase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293740)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable ATP-binding RNA helicase which may be involved in ribosome biogenesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BD6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BF0-1", "uniprot_id": [ { "id": "FHKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BF0", "type": "external" } ], "mass": 66318.0, "length": 593, "protein_name": "Probable serine/threonine-protein kinase fhkA", "gene_name": "fhkA", "organism": "Cellular slime mold", "refseq_name": "FHA domain-containing protein", "refseq_ac": [ { "id": "XP_629079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629079", "type": "external" } ], "gene_names_uniprotkb": "fhkA; DDB_G0293656; fhakA", "gene_names_refseq": "fhkA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase fhkA; 2.7.11.1; Forkhead-associated kinase protein A", "protein_names_refseq": "FHA domain-containing protein; RAD53 family protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293656)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BF5-1", "uniprot_id": [ { "id": "CUPD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BF5", "type": "external" } ], "mass": 70686.0, "length": 634, "protein_name": "Calcium up-regulated protein D", "gene_name": "cupD", "organism": "Cellular slime mold", "refseq_name": "calcium up-regulated protein", "refseq_ac": [ { "id": "XP_629074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629074", "type": "external" } ], "gene_names_uniprotkb": "cupD; DDB_G0293536", "gene_names_refseq": "cupD", "protein_names_uniprotkb": "Calcium up-regulated protein D", "protein_names_refseq": "calcium up-regulated protein; ricin B lectin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293536)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14871937;15875012", "class_list": "", "function": "May play an important role in stabilizing and/or regulating the cell membrane during Ca(2+) stress or certain stages of development., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7Z201", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0043157 response to cation stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BF5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BF6-1", "uniprot_id": [ { "id": "MCFN_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BF6", "type": "external" } ], "mass": 31687.0, "length": 298, "protein_name": "Mitochondrial substrate carrier family protein N", "gene_name": "mcfN", "organism": "Cellular slime mold", "refseq_name": "mitochondrial substrate carrier family protein", "refseq_ac": [ { "id": "XP_629073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629073", "type": "external" } ], "gene_names_uniprotkb": "mcfN; DDB_G0293646; slc25a3", "gene_names_refseq": "mcfN", "protein_names_uniprotkb": "Mitochondrial substrate carrier family protein N; Solute carrier family 25 member 3 homolog", "protein_names_refseq": "mitochondrial substrate carrier family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293646)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17442478", "class_list": "", "function": "Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+) (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006817 phosphate ion transport;GO:0035435 phosphate ion transmembrane transport;GO:1990547 mitochondrial phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BF6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BG3-1", "uniprot_id": [ { "id": "PONE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BG3", "type": "external" } ], "mass": 18932.0, "length": 171, "protein_name": "Ponticulin-like protein E", "gene_name": "ponE", "organism": "Cellular slime mold", "refseq_name": "ponticulin-related protein", "refseq_ac": [ { "id": "XP_629066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629066", "type": "external" } ], "gene_names_uniprotkb": "ponE; DDB_G0293634", "gene_names_refseq": "ponE", "protein_names_uniprotkb": "Ponticulin-like protein E", "protein_names_refseq": "ponticulin-related protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293634)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18522444", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BK1-1", "uniprot_id": [ { "id": "GGPPS_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BK1", "type": "external" } ], "mass": 34876.0, "length": 303, "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "ggps1", "organism": "Cellular slime mold", "refseq_name": "geranylgeranyl diphosphate synthase 1", "refseq_ac": [ { "id": "XP_629028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629028", "type": "external" } ], "gene_names_uniprotkb": "ggps1; DDB_G0293588", "gene_names_refseq": "ggps1", "protein_names_uniprotkb": "Geranylgeranyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.-; 2.5.1.10; 2.5.1.1; 2.5.1.29; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; GGPP synthase; GGPPSase; Geranylgeranyl diphosphate synthase; Geranyltranstransferase", "protein_names_refseq": "geranylgeranyl diphosphate synthase 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293588); (R-DDI-9969896)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.1", "type": "external" }, { "id": "2.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.10", "type": "external" }, { "id": "2.5.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.29", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0004161 dimethylallyltranstransferase activity;GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0046872 metal ion binding;GO:0004311 geranylgeranyl diphosphate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0033384 geranyl diphosphate biosynthetic process;GO:0045337 farnesyl diphosphate biosynthetic process;GO:0033386 geranylgeranyl diphosphate biosynthetic process;GO:0008299 isoprenoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BK2-1", "uniprot_id": [ { "id": "NCSEA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BK2", "type": "external" } ], "mass": 78438.0, "length": 714, "protein_name": "Neutral ceramidase A", "gene_name": "dcd2A", "organism": "Cellular slime mold", "refseq_name": "acid ceramidase", "refseq_ac": [ { "id": "XP_629027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629027", "type": "external" } ], "gene_names_uniprotkb": "dcd2A; DDB_G0293538; dcd; rsc25", "gene_names_refseq": "dcd2A", "protein_names_uniprotkb": "Neutral ceramidase A; 3.5.1.23; Acylsphingosine deacylase 2A; N-CDase A; N-acylsphingosine amidohydrolase 2A; NCDase A", "protein_names_refseq": "acid ceramidase; neutral/alkaline nonlysosomal ceramidase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293538); (R-DDI-9840310)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12943537;15875012", "class_list": "", "function": "Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 3.0. Has no activity toward glycosphingolipids, such as GalCer and Galbeta1-3GalNAcbeta1-4(NeuAcalpha2-3)Galbeta1-4Glcbeta1-1'Cer or sphingomyelin., [UniProtKB, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "O15913;Q75WL6", "ec_number_list": [ { "id": "3.5.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.23", "type": "external" } ], "go_molecular_function": "GO:0017040 N-acylsphingosine amidohydrolase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0046512 sphingosine biosynthetic process;GO:0046514 ceramide catabolic process;GO:0006672 ceramide metabolic process;GO:0042759 long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BL2-1", "uniprot_id": [ { "id": "EFS2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BL2", "type": "external" } ], "mass": 35333.0, "length": 296, "protein_name": "Putative pre-rRNA-processing protein esf2", "gene_name": "esf2", "organism": "Cellular slime mold", "refseq_name": "RNA-binding region RNP-1 domain-containing protein", "refseq_ac": [ { "id": "XP_629017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629017", "type": "external" } ], "gene_names_uniprotkb": "esf2; DDB_G0293576", "gene_names_refseq": "esf2", "protein_names_uniprotkb": "Putative pre-rRNA-processing protein esf2", "protein_names_refseq": "RNA-binding region RNP-1 domain-containing protein; U3 snoRNP-associated protein Esf2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293576)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May be involved in the small subunit (SSU) processome assembly and function, and in the 17S rRNA synthesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0034462 small-subunit processome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BL8-1", "uniprot_id": [ { "id": "LYSG5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BL8", "type": "external" } ], "mass": 24565.0, "length": 216, "protein_name": "Probable GH family 25 lysozyme 5", "gene_name": "DDB_G0293566", "organism": "Cellular slime mold", "refseq_name": "glycoside hydrolase family 25 protein", "refseq_ac": [ { "id": "XP_629011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629011", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0293566", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable GH family 25 lysozyme 5; 1,4-beta-N-acetylmuramidase 5; 3.2.1.17", "protein_names_refseq": "glycoside hydrolase family 25 protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293566)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "glycogene;glycosylhydrolase", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007165 signal transduction;GO:0042742 defense response to bacterium;GO:0031640 killing of cells of another organism;GO:0016998 cell wall macromolecule catabolic process;GO:0009253 peptidoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BM1-1", "uniprot_id": [ { "id": "RPA2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BM1", "type": "external" } ], "mass": 128285.0, "length": 1130, "protein_name": "DNA-directed RNA polymerase I subunit rpa2", "gene_name": "polr1b", "organism": "Cellular slime mold", "refseq_name": "RNA polymerase I, second largest subunit", "refseq_ac": [ { "id": "XP_629008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629008", "type": "external" } ], "gene_names_uniprotkb": "polr1b; DDB_G0293560; rpa2", "gene_names_refseq": "rpa2", "protein_names_uniprotkb": "DNA-directed RNA polymerase I subunit rpa2; 2.7.7.6; DNA-directed RNA polymerase I polypeptide 2; RNA polymerase I subunit 2", "protein_names_refseq": "RNA polymerase I, second largest subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293560); (R-DDI-73762); (R-DDI-73772)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.7.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.48", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0032549 ribonucleoside binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005736 RNA polymerase I complex", "go_biological_process": "GO:0006360 transcription by RNA polymerase I;GO:0006362 transcription elongation by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BM1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BM2-1", "uniprot_id": [ { "id": "PAP1A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BM2", "type": "external" } ], "mass": 62780.0, "length": 565, "protein_name": "Polyadenylate-binding protein 1-A", "gene_name": "pabpc1A", "organism": "Cellular slime mold", "refseq_name": "RNA recognition motif-containing protein RRM", "refseq_ac": [ { "id": "XP_629007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629007", "type": "external" } ], "gene_names_uniprotkb": "pabpc1A; DDB_G0293558", "gene_names_refseq": "pabpc1A", "protein_names_uniprotkb": "Polyadenylate-binding protein 1-A; PABP-1-A; Poly(A)-binding protein, cytoplasmic 1-A", "protein_names_refseq": "RNA recognition motif-containing protein RRM; RNA-binding region RNP-1 domain-containing protein; polyadenylate binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293558); (R-DDI-156827); (R-DDI-450408); (R-DDI-975956); (R-DDI-975957)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0008143 poly(A) binding;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0045335 phagocytic vesicle;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BM2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BM5-1", "uniprot_id": [ { "id": "BBP_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BM5", "type": "external" } ], "mass": 57513.0, "length": 501, "protein_name": "Branchpoint-bridging protein", "gene_name": "sf1", "organism": "Cellular slime mold", "refseq_name": "CCHC-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_629004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629004", "type": "external" } ], "gene_names_uniprotkb": "sf1; DDB_G0293554", "gene_names_refseq": "sf1", "protein_names_uniprotkb": "Branchpoint-bridging protein; Splicing factor 1", "protein_names_refseq": "CCHC-type zinc finger-containing protein; splicing factor 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293554)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Necessary for the splicing of pre-mRNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000243 commitment complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BM7-1", "uniprot_id": [ { "id": "PPK1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BM7", "type": "external" } ], "mass": 118182.0, "length": 1053, "protein_name": "Polyphosphate kinase", "gene_name": "ppkA", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ppkA; DDB_G0293524", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyphosphate kinase; 2.7.4.1; ATP-polyphosphate phosphotransferase; PPK1; Polyphosphate kinase 1; Polyphosphoric acid kinase", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293524)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15701689;15875012;17940044", "class_list": "", "function": "Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Produces polyP in a broad range of chain lengths (50-300 Pi residues). Involved in development (growth and fruiting body formation), sporulation, phagocytosis, cell division and the late stages of cytokinesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9U6U8", "ec_number_list": [ { "id": "2.7.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008976 polyphosphate kinase activity", "go_cellular_component": "GO:0016020 membrane;GO:0031982 vesicle;GO:0009358 polyphosphate kinase complex", "go_biological_process": "GO:0006909 phagocytosis;GO:0000281 mitotic cytokinesis;GO:0006797 polyphosphate metabolic process;GO:0006799 polyphosphate biosynthetic process;GO:0009847 spore germination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54BM7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BN0-1", "uniprot_id": [ { "id": "TMEDB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BN0", "type": "external" } ], "mass": 23798.0, "length": 209, "protein_name": "Transmembrane emp24 domain-containing protein B", "gene_name": "empB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_628999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628999", "type": "external" } ], "gene_names_uniprotkb": "empB; DDB_G0293540", "gene_names_refseq": "empB", "protein_names_uniprotkb": "Transmembrane emp24 domain-containing protein B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293540); (R-DDI-6807878); (R-DDI-6811434)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Could have a role in the budding of coatomer-coated and other species of coated vesicles., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q769F8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0030659 cytoplasmic vesicle membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BN0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BN2-1", "uniprot_id": [ { "id": "Q54BN2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BN2", "type": "external" } ], "mass": 78635.0, "length": 689, "protein_name": "Double-strand break repair protein", "gene_name": "mre11", "organism": "Cellular slime mold", "refseq_name": "3'-5' exonuclease", "refseq_ac": [ { "id": "XP_628997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628997", "type": "external" } ], "gene_names_uniprotkb": "mre11; DDB_G0293546", "gene_names_refseq": "mre11", "protein_names_uniprotkb": "Double-strand break repair protein", "protein_names_refseq": "3'-5' exonuclease; DNA repair exonuclease", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293546); (R-DDI-1834949); (R-DDI-2559586); (R-DDI-5685938); (R-DDI-5693548); (R-DDI-5693565); (R-DDI-5693607); (R-DDI-5693616)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008296 3'-5'-DNA exonuclease activity;GO:0030145 manganese ion binding;GO:0004519 endonuclease activity;GO:0008408 3'-5' exonuclease activity;GO:0000014 single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "GO:0035861 site of double-strand break;GO:0030870 Mre11 complex", "go_biological_process": "GO:0000723 telomere maintenance;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0000724 double-strand break repair via homologous recombination;GO:0007095 mitotic G2 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BN3-1", "uniprot_id": [ { "id": "RFC3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BN3", "type": "external" } ], "mass": 39551.0, "length": 347, "protein_name": "Probable replication factor C subunit 3", "gene_name": "rfc3", "organism": "Cellular slime mold", "refseq_name": "replication factor C subunit", "refseq_ac": [ { "id": "XP_628996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628996", "type": "external" } ], "gene_names_uniprotkb": "rfc3; DDB_G0293702", "gene_names_refseq": "rfc3", "protein_names_uniprotkb": "Probable replication factor C subunit 3; Activator 1 subunit 3", "protein_names_refseq": "replication factor C subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293702); (R-DDI-5685938); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-69091)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003689 DNA clamp loader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031391 Elg1 RFC-like complex;GO:0005663 DNA replication factor C complex", "go_biological_process": "GO:0006272 leading strand elongation;GO:0006281 DNA repair;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54BN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BP1-1", "uniprot_id": [ { "id": "Q54BP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BP1", "type": "external" } ], "mass": 248357.0, "length": 2110, "protein_name": "Centrosomal protein 248 kDa", "gene_name": "DDB_G0293544", "organism": "Cellular slime mold", "refseq_name": "centrosomal protein 248 kDa", "refseq_ac": [ { "id": "XP_628988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628988", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0293544", "gene_names_refseq": "", "protein_names_uniprotkb": "Centrosomal protein 248 kDa", "protein_names_refseq": "centrosomal protein 248 kDa", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293544)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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"record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BQ5-1", "uniprot_id": [ { "id": "NSF1C_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BQ5", "type": "external" } ], "mass": 45471.0, "length": 415, "protein_name": "NSFL1 cofactor p47 homolog", "gene_name": "nsfl1c", "organism": "Cellular slime mold", "refseq_name": "UBX domain-containing protein", "refseq_ac": [ { "id": "XP_629097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629097", "type": "external" } ], "gene_names_uniprotkb": "nsfl1c; DDB_G0293498", "gene_names_refseq": "", "protein_names_uniprotkb": "NSFL1 cofactor p47 homolog", "protein_names_refseq": "UBX domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293498)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Regulates the centrosomal levels of kinase aurK/Aurora during mitotic progression by promoting aurK removal from centrosomes in prophase. 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The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0032580 Golgi cisterna membrane;GO:0070765 gamma-secretase complex", "go_biological_process": "GO:0007219 Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BT3-1", "uniprot_id": [ { "id": "ABCB2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BT3", "type": "external" } ], "mass": 153407.0, "length": 1397, "protein_name": "ABC transporter B family member 2", "gene_name": "abcB2", "organism": "Cellular slime mold", "refseq_name": "ABC transporter B family protein", "refseq_ac": [ { "id": "XP_629136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629136", "type": "external" } ], "gene_names_uniprotkb": "abcB2; DDB_G0293438", "gene_names_refseq": "abcB2", "protein_names_uniprotkb": "ABC transporter B family member 2; ABC transporter ABCB.2", "protein_names_refseq": "ABC transporter B family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293438); (R-DDI-1369007); (R-DDI-159418); (R-DDI-193368); (R-DDI-382556); (R-DDI-9754706); (R-DDI-9757110); (R-DDI-983170)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "12456012;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9W5", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BT3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BT5-1", "uniprot_id": [ { "id": "ABCA3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BT5", "type": "external" } ], "mass": 191800.0, "length": 1702, "protein_name": "ABC transporter A family member 3", "gene_name": "abcA3", "organism": "Cellular slime mold", "refseq_name": "ABC transporter A family protein", "refseq_ac": [ { "id": "XP_629134", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629134", "type": "external" } ], "gene_names_uniprotkb": "abcA3; DDB_G0293436", "gene_names_refseq": "abcA3", "protein_names_uniprotkb": "ABC transporter A family member 3; ABC transporter ABCA.3", "protein_names_refseq": "ABC transporter A family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293436); (R-DDI-1369062); (R-DDI-2453902); (R-DDI-382556); (R-DDI-5683826); (R-DDI-6798695); (R-DDI-8963896)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "12456012;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T6J4", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006869 lipid transport;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BT5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BU4-1", "uniprot_id": [ { "id": "ABCB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BU4", "type": "external" } ], "mass": 101293.0, "length": 909, "protein_name": "ABC transporter B family member 1", "gene_name": "abcB1", "organism": "Cellular slime mold", "refseq_name": "ABC transporter B family protein", "refseq_ac": [ { "id": "XP_629144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629144", "type": "external" } ], "gene_names_uniprotkb": "abcB1; DDB_G0293416; mrpA", "gene_names_refseq": "abcB1", "protein_names_uniprotkb": "ABC transporter B family member 1; ABC transporter ABCB.1", "protein_names_refseq": "ABC transporter B family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293416)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12456012;15875012", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9W6", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006935 chemotaxis;GO:0055085 transmembrane transport;GO:0006972 hyperosmotic response;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BU4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BW5-1", "uniprot_id": [ { "id": "DUT_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BW5", "type": "external" } ], "mass": 19532.0, "length": 179, "protein_name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "gene_name": "dut", "organism": "Cellular slime mold", "refseq_name": "dUTP diphosphatase", "refseq_ac": [ { "id": "XP_629169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629169", "type": "external" } ], "gene_names_uniprotkb": "dut; DDB_G0293374", "gene_names_refseq": "dut", "protein_names_uniprotkb": "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; 3.6.1.23; dUTP pyrophosphatase; dUTPase", "protein_names_refseq": "dUTP diphosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293374); (R-DDI-499943)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;31910901", "class_list": "", "function": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.23", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004170 dUTP diphosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006226 dUMP biosynthetic process;GO:0046081 dUTP catabolic process;GO:0009213 pyrimidine deoxyribonucleoside triphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54BX3-1", "uniprot_id": [ { "id": "HSL63_DICDI", "url": "https://www.uniprot.org/uniprot/Q54BX3", "type": "external" } ], "mass": 9111.0, "length": 88, "protein_name": "serine-rich chaperone protein 1", "gene_name": "hssl63", "organism": "Cellular slime mold", "refseq_name": "hssA/2C/7E family protein", "refseq_ac": [ { "id": "XP_629183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629183", "type": "external" } ], "gene_names_uniprotkb": "hssl63; DDB_G0293362; srcp1", "gene_names_refseq": "", "protein_names_uniprotkb": "serine-rich chaperone protein 1; HssA/B-like protein 63", "protein_names_refseq": "hssA/2C/7E family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293362)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;30029002", "class_list": "", "function": "Chaperone that suppresses aggregation of proteins with long polyglutamine (polyQ) tracts (PubMed:30029002). Acts by promoting degradation of polyQ aggregates by the proteasome (PubMed:30029002)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0101031 protein folding chaperone complex", "go_biological_process": "GO:0006457 protein folding;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54BX3-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C16-1", "uniprot_id": [ { "id": "SGMB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C16", "type": "external" } ], "mass": 72204.0, "length": 637, "protein_name": "Sphingomyelin phosphodiesterase B", "gene_name": "sgmB", "organism": "Cellular slime mold", "refseq_name": "metallophosphoesterase domain-containing protein", "refseq_ac": [ { "id": "XP_629250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629250", "type": "external" } ], "gene_names_uniprotkb": "sgmB; DDB_G0293210", "gene_names_refseq": "sgmB", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase B; 3.1.4.-; Acid sphingomyelinase B; aSMase B", "protein_names_refseq": "metallophosphoesterase domain-containing protein; saposin B domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293210); (R-DDI-9840310)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Converts sphingomyelin to ceramide., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008081 phosphoric diester hydrolase activity;GO:0004767 sphingomyelin phosphodiesterase activity;GO:0016798 hydrolase activity, acting on glycosyl bonds", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0006685 sphingomyelin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C18-1", "uniprot_id": [ { "id": "Y9452_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C18", "type": "external" } ], "mass": 58102.0, "length": 516, "protein_name": "Probable serine/threonine-protein kinase DDB_G0293276", "gene_name": "DDB_G0293276", "organism": "Cellular slime mold", "refseq_name": "MAST family protein kinase", "refseq_ac": [ { "id": "XP_629248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629248", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0293276", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0293276; 2.7.11.1", "protein_names_refseq": "MAST family protein kinase; protein kinase, AGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293276)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C21-1", "uniprot_id": [ { "id": "Q54C21_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C21", "type": "external" } ], "mass": 96530.0, "length": 846, "protein_name": "ATP-dependent DNA helicase", "gene_name": "DDB_G0293212", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629245", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0293212", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-dependent DNA helicase; 5.6.2.3", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293212)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004842 ubiquitin-protein transferase activity;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C21-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C24-1", "uniprot_id": [ { "id": "VPS35_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C24", "type": "external" } ], "mass": 89077.0, "length": 781, "protein_name": "Vacuolar protein sorting-associated protein 35", "gene_name": "vps35", "organism": "Cellular slime mold", "refseq_name": "vacuolar sorting protein 35", "refseq_ac": [ { "id": "XP_629242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629242", "type": "external" } ], "gene_names_uniprotkb": "vps35; DDB_G0293218", "gene_names_refseq": "vps35", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 35", "protein_names_refseq": "vacuolar sorting protein 35", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293218); (R-DDI-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030906 retromer, cargo-selective complex;GO:0005829 cytosol;GO:0005770 late endosome;GO:0010008 endosome membrane;GO:0030904 retromer complex", "go_biological_process": "GO:0045053 protein retention in Golgi apparatus;GO:0006886 intracellular protein transport;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C24-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C25-1", "uniprot_id": [ { "id": "GPN1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C25", "type": "external" } ], "mass": 45457.0, "length": 396, "protein_name": "GPN-loop GTPase 1", "gene_name": "gpn1", "organism": "Cellular slime mold", "refseq_name": "AAA ATPase domain-containing protein", "refseq_ac": [ { "id": "XP_629241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629241", "type": "external" } ], "gene_names_uniprotkb": "gpn1; DDB_G0293220; xab1", "gene_names_refseq": "gpn1", "protein_names_uniprotkb": "GPN-loop GTPase 1; 3.6.5.-; XPA-binding protein 1 homolog", "protein_names_refseq": "AAA ATPase domain-containing protein; GPN-loop GTPase 1; Ras GTPase domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293220)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Small GTPase involved in the correct assembly of RNA polymerase II (RNAPII) complex, ensuring proper nuclear import of RNAPII (By similarity). In vitro, exhibits a chaperone-like activity and a chaperone substrate protein can stimulate its GTPase activity. It is proposed to bind exposed hydrophobic peptide regions of newly synthesized RNAP II subunit, triggering the opening of a hydrophobic pocket in its GDP-bound state. This interaction likely traps exposed hydrophobic regions, preventing misassembly and providing a time window for association with the cognate RNAP II subunit. Peptide binding promotes GDP release, and increasing GTP affinity to facilitate GTP rebinding. Subsequent GTP hydrolysis would then lead to the release of the bound RNAP II subunit to enable association with cognate subunits and RNAP II assembly (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C27-1", "uniprot_id": [ { "id": "OST1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C27", "type": "external" } ], "mass": 52411.0, "length": 460, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "ost1", "organism": "Cellular slime mold", "refseq_name": "dolichyl-diphosphooligosaccharide-protein glycotransferase", "refseq_ac": [ { "id": "XP_629239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629239", "type": "external" } ], "gene_names_uniprotkb": "ost1; DDB_G0293224; rpn1", "gene_names_refseq": "ost1", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Oligosaccharyl transferase subunit alpha; RPN-I; Ribophorin I; Ribophorin-1", "protein_names_refseq": "dolichyl-diphosphooligosaccharide-protein glycotransferase; oligosaccharyltransferase alpha subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293224)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16469056", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54C27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C28-1", "uniprot_id": [ { "id": "Q54C28_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C28", "type": "external" } ], "mass": 57465.0, "length": 523, "protein_name": "RuvB-like helicase", "gene_name": "rvb1", "organism": "Cellular slime mold", "refseq_name": "AAA ATPase domain-containing protein", "refseq_ac": [ { "id": "XP_629238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629238", "type": "external" } ], "gene_names_uniprotkb": "rvb1; DDB_G0293226", "gene_names_refseq": "rvb1", "protein_names_uniprotkb": "RuvB-like helicase; 3.6.4.12", "protein_names_refseq": "AAA ATPase domain-containing protein; RuvB-like protein 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293226); (R-DDI-5689880)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0097255 R2TP complex;GO:0031011 Ino80 complex;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000492 box C/D snoRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C28-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C30-1", "uniprot_id": [ { "id": "CDC26_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C30", "type": "external" } ], "mass": 8196.0, "length": 69, "protein_name": "Anaphase-promoting complex subunit cdc26", "gene_name": "cdc26", "organism": "Cellular slime mold", "refseq_name": "subunit of anaphase promoting complex", "refseq_ac": [ { "id": "XP_629236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629236", "type": "external" } ], "gene_names_uniprotkb": "cdc26; DDB_G0293230", "gene_names_refseq": "cdc26", "protein_names_uniprotkb": "Anaphase-promoting complex subunit cdc26; Cell division cycle protein 26 homolog", "protein_names_refseq": "subunit of anaphase promoting complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293230); (R-DDI-141430); (R-DDI-174048); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-174184); (R-DDI-176407); (R-DDI-176408); (R-DDI-176409); (R-DDI-176412); (R-DDI-179409); (R-DDI-2467813); (R-DDI-2559582); (R-DDI-69017); (R-DDI-983168)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0070979 protein K11-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C45-1", "uniprot_id": [ { "id": "FRDA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C45", "type": "external" } ], "mass": 22206.0, "length": 193, "protein_name": "Frataxin, mitochondrial", "gene_name": "fxn", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629221", "type": "external" } ], "gene_names_uniprotkb": "fxn; DDB_G0293246", "gene_names_refseq": "fxn", "protein_names_uniprotkb": "Frataxin, mitochondrial; 1.16.3.1; Fxn", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293246); (R-DDI-1362409); (R-DDI-9854311); (R-DDI-9865881)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.16.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1", "type": "external" }, { "id": "7.1.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.8", "type": "external" }, { "id": "2.8.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.7", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0051537 2 iron, 2 sulfur cluster binding;GO:0008198 ferrous iron binding;GO:0004322 ferroxidase activity;GO:0034986 iron chaperone activity;GO:0008199 ferric iron binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006879 intracellular iron ion homeostasis;GO:0006783 heme biosynthetic process;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C49-1", "uniprot_id": [ { "id": "EIF3F_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C49", "type": "external" } ], "mass": 31754.0, "length": 284, "protein_name": "Eukaryotic translation initiation factor 3 subunit F", "gene_name": "eif3f", "organism": "Cellular slime mold", "refseq_name": "Mov34/MPN/PAD-1 family protein", "refseq_ac": [ { "id": "XP_629217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629217", "type": "external" } ], "gene_names_uniprotkb": "eif3f; DDB_G0293254; eif3s5", "gene_names_refseq": "eIF3s5", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit F; Eukaryotic translation initiation factor 3 subunit 5; eIF3f", "protein_names_refseq": "Mov34/MPN/PAD-1 family protein; eIF-3 epsilon; eukaryotic translation initiation factor 3 subunit 5", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293254); (R-DDI-156827); (R-DDI-72689); (R-DDI-72695); (R-DDI-72702)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C55-1", "uniprot_id": [ { "id": "PEX14_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C55", "type": "external" } ], "mass": 83361.0, "length": 748, "protein_name": "Peroxisomal membrane protein PEX14", "gene_name": "pex14", "organism": "Cellular slime mold", "refseq_name": "peroxin 14", "refseq_ac": [ { "id": "XP_629211", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629211", "type": "external" } ], "gene_names_uniprotkb": "pex14; DDB_G0293264", "gene_names_refseq": "pex14", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX14; PTS1 receptor-docking protein; Peroxin-14", "protein_names_refseq": "peroxin 14; peroxisomal biogenesis factor 14; transmembrane protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293264); (R-DDI-8866654); (R-DDI-9033241); (R-DDI-9603798)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:1990429 peroxisomal importomer complex;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0006625 protein targeting to peroxisome;GO:0016560 protein import into peroxisome matrix, docking", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54C55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C70-1", "uniprot_id": [ { "id": "ODPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C70", "type": "external" } ], "mass": 41988.0, "length": 377, "protein_name": "Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial", "gene_name": "pdhA", "organism": "Cellular slime mold", "refseq_name": "pyruvate dehydrogenase E1 alpha subunit", "refseq_ac": [ { "id": "XP_629349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629349", "type": "external" } ], "gene_names_uniprotkb": "pdhA; DDB_G0292994", "gene_names_refseq": "pdhA", "protein_names_uniprotkb": "Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; 1.2.4.1; PDHE1-A", "protein_names_refseq": "pyruvate dehydrogenase E1 alpha subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292994); (R-DDI-9861559)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.12", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "1.8.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.4", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045335 phagocytic vesicle;GO:0045254 pyruvate dehydrogenase complex", "go_biological_process": "GO:0006086 pyruvate decarboxylation to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54C70-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C71-1", "uniprot_id": [ { "id": "KXCB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C71", "type": "external" } ], "mass": 125581.0, "length": 1125, "protein_name": "Kinase and exchange factor for Rac B", "gene_name": "kxcB", "organism": "Cellular slime mold", "refseq_name": "DH domain-containing protein", "refseq_ac": [ { "id": "XP_629348", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629348", "type": "external" } ], "gene_names_uniprotkb": "kxcB; DDB_G0293124; RacGEF", "gene_names_refseq": "kxcB", "protein_names_uniprotkb": "Kinase and exchange factor for Rac B; 2.7.11.1; Serine/threonine-protein kinase kxcB", "protein_names_refseq": "DH domain-containing protein; PH domain-containing protein; RhoGEF domain-containing protein; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293124)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16762450", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54C71-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C92-1", "uniprot_id": [ { "id": "CSN6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C92", "type": "external" } ], "mass": 35107.0, "length": 309, "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "csn6", "organism": "Cellular slime mold", "refseq_name": "COP9 signalosome complex subunit 6", "refseq_ac": [ { "id": "XP_629327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629327", "type": "external" } ], "gene_names_uniprotkb": "csn6; DDB_G0293180", "gene_names_refseq": "CSN6", "protein_names_uniprotkb": "COP9 signalosome complex subunit 6; Signalosome subunit 6", "protein_names_refseq": "COP9 signalosome complex subunit 6; Mov34/MPN/PAD-1 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293180); (R-DDI-5696394); (R-DDI-6781823); (R-DDI-8856825); (R-DDI-8951664)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "15875012;16781008;16926386", "class_list": "", "function": "Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2PQ73", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity", "go_cellular_component": "GO:0045335 phagocytic vesicle;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0000338 protein deneddylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54C92-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54C94-1", "uniprot_id": [ { "id": "GEFF_DICDI", "url": "https://www.uniprot.org/uniprot/Q54C94", "type": "external" } ], "mass": 126465.0, "length": 1127, "protein_name": "Ras guanine nucleotide exchange factor F", "gene_name": "gefF", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor", "refseq_ac": [ { "id": "XP_629325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629325", "type": "external" } ], "gene_names_uniprotkb": "gefF; DDB_G0293006; rasGEFF", "gene_names_refseq": "gefF", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor F; RasGEF domain-containing protein F", "protein_names_refseq": "Ras guanine nucleotide exchange factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293006); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "15875012;16086850;18559084;18590548", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q8IS17", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0044354 macropinosome", "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:0044351 macropinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54C94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CA8-1", "uniprot_id": [ { "id": "Q54CA8_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CA8", "type": "external" } ], "mass": 241715.0, "length": 2147, "protein_name": "DOCK family protein", "gene_name": "zizB", "organism": "Cellular slime mold", "refseq_name": "DOCK family protein", "refseq_ac": [ { "id": "XP_629311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629311", "type": "external" } ], "gene_names_uniprotkb": "zizB; DDB_G0293084", "gene_names_refseq": "zizB", "protein_names_uniprotkb": "DOCK family protein", "protein_names_refseq": "DOCK family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293084); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423); (R-DDI-983231)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005938 cell cortex", "go_biological_process": "GO:0046847 filopodium assembly;GO:0007264 small GTPase-mediated signal transduction;GO:0035023 regulation of Rho protein signal transduction;GO:0000281 mitotic cytokinesis;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CA8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CC5-1", "uniprot_id": [ { "id": "EIF3E_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CC5", "type": "external" } ], "mass": 60041.0, "length": 525, "protein_name": "Eukaryotic translation initiation factor 3 subunit E", "gene_name": "eif3E", "organism": "Cellular slime mold", "refseq_name": "eIF-3 p48", "refseq_ac": [ { "id": "XP_629294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629294", "type": "external" } ], "gene_names_uniprotkb": "eif3E; DDB_G0293052; eif3s6", "gene_names_refseq": "eIF3s6", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit E; Eukaryotic translation initiation factor 3 subunit 6; eIF3e", "protein_names_refseq": "eIF-3 p48; eukaryotic translation initiation factor 3 subunit 6; proteasome component region PCI domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293052); (R-DDI-156827); (R-DDI-72689); (R-DDI-72695); (R-DDI-72702)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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"Q54CD6-1", "uniprot_id": [ { "id": "DDX5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CD6", "type": "external" } ], "mass": 80799.0, "length": 697, "protein_name": "Probable ATP-dependent RNA helicase ddx5", "gene_name": "ddx5", "organism": "Cellular slime mold", "refseq_name": "DEAD/DEAH box helicase", "refseq_ac": [ { "id": "XP_629283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629283", "type": "external" } ], "gene_names_uniprotkb": "ddx5; DDB_G0293036", "gene_names_refseq": "ddx5", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase ddx5; 3.6.4.13; DEAD box protein 5", "protein_names_refseq": "DEAD/DEAH box helicase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293036)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable ATP-dependent RNA helicase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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domain-containing protein", "protein_names_refseq": "CHR group protein; SNF2-related domain-containing protein; chromo domain-containing protein; helicase, C-terminal domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293012); (R-DDI-9943962)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0010628 positive regulation of gene expression;GO:0010468 regulation of gene expression;GO:0019954 asexual reproduction;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CF8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CG0-1", "uniprot_id": [ { "id": "ABCGA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CG0", "type": "external" } ], "mass": 166602.0, "length": 1466, "protein_name": "ABC transporter G family member 10", "gene_name": "abcG10", "organism": "Cellular slime mold", "refseq_name": "ABC transporter G family protein", "refseq_ac": [ { "id": "XP_629362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629362", "type": "external" } ], "gene_names_uniprotkb": "abcG10; DDB_G0292986", "gene_names_refseq": "abcG10", "protein_names_uniprotkb": "ABC transporter G family member 10; ABC transporter ABCG.10", "protein_names_refseq": "ABC transporter G family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292986)", "pathway_count": 1, "publication_count": 2, 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8T682", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0009617 response to bacterium;GO:0031152 aggregation involved in sorocarp development;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54CG0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CH1-1", "uniprot_id": [ { "id": "ADCA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CH1", "type": "external" } ], "mass": 64537.0, "length": 580, "protein_name": "Arrestin domain-containing protein A", "gene_name": "adcA", "organism": "Cellular slime mold", "refseq_name": "FYVE-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_629445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629445", "type": "external" } ], "gene_names_uniprotkb": "adcA; DDB_G0292924", "gene_names_refseq": "adcA", "protein_names_uniprotkb": "Arrestin domain-containing protein A", "protein_names_refseq": "FYVE-type zinc finger-containing protein; arrestin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292924)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16512674", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008270 zinc ion binding;GO:0032266 phosphatidylinositol-3-phosphate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0016020 membrane;GO:0045335 phagocytic vesicle;GO:0044354 macropinosome", "go_biological_process": "GO:0034605 cellular response to heat;GO:0034599 cellular response to oxidative stress;GO:0071474 cellular hyperosmotic response;GO:0080135 regulation of cellular response to stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54CH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CH3-1", "uniprot_id": [ { "id": "Q54CH3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CH3", "type": "external" } ], "mass": 51642.0, "length": 453, "protein_name": "Phosphatase and tensin homolog", "gene_name": "DDB_G0292920", "organism": "Cellular slime mold", "refseq_name": "C2 tensin-type domain-containing protein", "refseq_ac": [ { "id": "XP_629443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629443", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292920", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatase and tensin homolog", "protein_names_refseq": "C2 tensin-type domain-containing protein; phosphatase tensin type domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292920)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity;GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0042995 cell projection", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0008285 negative regulation of cell population proliferation;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0048870 cell motility;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CH3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CI8-1", "uniprot_id": [ { "id": "DC1L1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CI8", "type": "external" } ], "mass": 56713.0, "length": 504, "protein_name": "Cytoplasmic dynein 1 light intermediate chain 1", "gene_name": "dync1li1", "organism": "Cellular slime mold", "refseq_name": "dynein light intermediate chain", "refseq_ac": [ { "id": "XP_629428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629428", "type": "external" } ], "gene_names_uniprotkb": "dync1li1; DDB_G0292904", "gene_names_refseq": "dync1li1", "protein_names_uniprotkb": "Cytoplasmic dynein 1 light intermediate chain 1; Dynein light intermediate chain 1, cytosolic", "protein_names_refseq": "dynein light intermediate chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292904); (R-DDI-6798695); (R-DDI-6807878); (R-DDI-9646399)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005868 cytoplasmic dynein complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CI8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CJ4-1", "uniprot_id": [ { "id": "ELOA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CJ4", "type": "external" } ], "mass": 32176.0, "length": 271, "protein_name": "Fatty acid elongase A", "gene_name": "eloA", "organism": "Cellular slime mold", "refseq_name": "GNS1/SUR4 family protein", "refseq_ac": [ { "id": "XP_629422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629422", "type": "external" } ], "gene_names_uniprotkb": "eloA; DDB_G0292896", "gene_names_refseq": "eloA", "protein_names_uniprotkb": "Fatty acid elongase A; 2.3.1.199; 3-keto acyl-CoA synthase eloA; Elongation of fatty acids protein A; Very-long-chain 3-oxoacyl-CoA synthase A", "protein_names_refseq": "GNS1/SUR4 family protein; fatty acid elongase ELO; long chain fatty acid elongase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292896)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;18590548;18621026", "class_list": "", "function": "Fatty acid elongase with strict substrate specificity for monounsaturated fatty acids, in particular 16:1 (delta-9) to produce the unusual 18:1 (delta-11) fatty acid., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.199", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199", "type": "external" } ], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid;GO:0019367 fatty acid elongation, saturated fatty acid;GO:0042761 very long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54CJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CK6-1", "uniprot_id": [ { "id": "VTI1A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CK6", "type": "external" } ], "mass": 25225.0, "length": 217, "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "vti1A", "organism": "Cellular slime mold", "refseq_name": "v-SNARE family protein", "refseq_ac": [ { "id": "XP_629410", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629410", "type": "external" } ], "gene_names_uniprotkb": "vti1A; DDB_G0292974; vti1", "gene_names_refseq": "vti1A", "protein_names_uniprotkb": "Vesicle transport through interaction with t-SNAREs homolog 1A", "protein_names_refseq": "v-SNARE family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292974); (R-DDI-114608); (R-DDI-6811438); (R-DDI-6811440)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "11923193;12175335;15875012", "class_list": "", "function": "V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:0031902 late endosome membrane;GO:0012507 ER to Golgi transport vesicle membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0006906 vesicle fusion;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54CK6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CK9-1", "uniprot_id": [ { "id": "WASH1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CK9", "type": "external" } ], "mass": 50922.0, "length": 472, "protein_name": "WAS protein family homolog DDB_G0292878", "gene_name": "DDB_G0292878", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629407", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292878", "gene_names_refseq": "", "protein_names_uniprotkb": "WAS protein family homolog DDB_G0292878", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292878)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0032010 phagolysosome;GO:0071203 WASH complex", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0030041 actin filament polymerization;GO:0009306 protein secretion;GO:0034314 Arp2/3 complex-mediated actin nucleation;GO:2001137 positive regulation of endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CL3-1", "uniprot_id": [ { "id": "PEX13_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CL3", "type": "external" } ], "mass": 60573.0, "length": 570, "protein_name": "Peroxisomal membrane protein PEX13", "gene_name": "pex13", "organism": "Cellular slime mold", "refseq_name": "SH3 domain-containing protein", "refseq_ac": [ { "id": "XP_629403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629403", "type": "external" } ], "gene_names_uniprotkb": "pex13; DDB_G0292870", "gene_names_refseq": "pex13", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX13; Peroxin-13", "protein_names_refseq": "SH3 domain-containing protein; peroxin 13; peroxisomal biogenesis factor 13; transmembrane protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292870); (R-DDI-8866654); (R-DDI-9033241); (R-DDI-9603798)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:1990429 peroxisomal importomer complex;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0016560 protein import into peroxisome matrix, docking", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CM0-1", "uniprot_id": [ { "id": "PPT3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CM0", "type": "external" } ], "mass": 33050.0, "length": 289, "protein_name": "Palmitoyl-protein thioesterase 3", "gene_name": "ppt3", "organism": "Cellular slime mold", "refseq_name": "palmitoyl-protein thioesterase 3", "refseq_ac": [ { "id": "XP_629396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629396", "type": "external" } ], "gene_names_uniprotkb": "ppt3; DDB_G0292862", "gene_names_refseq": "ppt3", "protein_names_uniprotkb": "Palmitoyl-protein thioesterase 3; 3.1.2.22; PPT-3; Palmitoyl-protein hydrolase 3", "protein_names_refseq": "palmitoyl-protein thioesterase 3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292862)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" } ], "go_molecular_function": "GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CN7-1", "uniprot_id": [ { "id": "CYSK_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CN7", "type": "external" } ], "mass": 41101.0, "length": 378, "protein_name": "Cysteine synthase", "gene_name": "cysK", "organism": "Cellular slime mold", "refseq_name": "cysteine synthase", "refseq_ac": [ { "id": "XP_629379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629379", "type": "external" } ], "gene_names_uniprotkb": "cysK; DDB_G0292840", "gene_names_refseq": "cysK", "protein_names_uniprotkb": "Cysteine synthase; 2.5.1.47; CSase; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL", "protein_names_refseq": "cysteine synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292840)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.47", "type": "external" } ], "go_molecular_function": "GO:0004124 cysteine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006535 cysteine biosynthetic process from serine;GO:0019344 cysteine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CP1-1", "uniprot_id": [ { "id": "RRP8_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CP1", "type": "external" } ], "mass": 45193.0, "length": 390, "protein_name": "Ribosomal RNA-processing protein 8", "gene_name": "rrp8", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629375", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629375", "type": "external" } ], "gene_names_uniprotkb": "rrp8; DDB_G0292960", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribosomal RNA-processing protein 8; 2.1.1.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292960)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable methyltransferase required to silence rDNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005677 chromatin silencing complex;GO:0033553 rDNA heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006364 rRNA processing;GO:0032259 methylation;GO:0000183 rDNA heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CP4-1", "uniprot_id": [ { "id": "MCM5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CP4", "type": "external" } ], "mass": 84221.0, "length": 757, "protein_name": "DNA replication licensing factor mcm5", "gene_name": "mcm5", "organism": "Cellular slime mold", "refseq_name": "MCM family protein", "refseq_ac": [ { "id": "XP_629372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629372", "type": "external" } ], "gene_names_uniprotkb": "mcm5; DDB_G0292958", "gene_names_refseq": "mcm5", "protein_names_uniprotkb": "DNA replication licensing factor mcm5; 3.6.4.12", "protein_names_refseq": "MCM family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292958); (R-DDI-68867); (R-DDI-68949); (R-DDI-68962); (R-DDI-69052)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0042555 MCM complex", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CP4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CR9-1", "uniprot_id": [ { "id": "DNLI4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CR9", "type": "external" } ], "mass": 124791.0, "length": 1088, "protein_name": "DNA ligase 4", "gene_name": "lig4", "organism": "Cellular slime mold", "refseq_name": "BRCT domain-containing protein", "refseq_ac": [ { "id": "XP_629472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629472", "type": "external" } ], "gene_names_uniprotkb": "lig4; DDB_G0292760", "gene_names_refseq": "lig4", "protein_names_uniprotkb": "DNA ligase 4; 6.5.1.1; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4", "protein_names_refseq": "BRCT domain-containing protein; DNA ligase IV", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292760); (R-DDI-5693571)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0032807 DNA ligase IV complex;GO:0005634 nucleus;GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006310 DNA recombination;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0000012 single strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CR9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CS2-1", "uniprot_id": [ { "id": "CUL4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CS2", "type": "external" } ], "mass": 92291.0, "length": 802, "protein_name": "Cullin-4", "gene_name": "culD", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629469", "type": "external" } ], "gene_names_uniprotkb": "culD; DDB_G0292794; cul4", "gene_names_refseq": "culD", "protein_names_uniprotkb": "Cullin-4; CUL-4; Cullin-D", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292794); (R-DDI-5696394); (R-DDI-5696395); (R-DDI-6781823); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-8951664)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0160072 ubiquitin ligase complex scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CS2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CS8-1", "uniprot_id": [ { "id": "PEX6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CS8", "type": "external" } ], "mass": 137009.0, "length": 1201, "protein_name": "Peroxisomal ATPase PEX6", "gene_name": "pex6", "organism": "Cellular slime mold", "refseq_name": "AAA ATPase domain-containing protein", "refseq_ac": [ { "id": "XP_629463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629463", "type": "external" } ], "gene_names_uniprotkb": "pex6; DDB_G0292788", "gene_names_refseq": "pex6", "protein_names_uniprotkb": "Peroxisomal ATPase PEX6; 3.6.4.-; Peroxin-6; Peroxisomal biogenesis factor 6", "protein_names_refseq": "AAA ATPase domain-containing protein; peroxin 6; peroxisomal biogenesis factor 6", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292788)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005829 cytosol", "go_biological_process": "GO:0043335 protein unfolding;GO:0007031 peroxisome organization;GO:0016558 protein import into peroxisome matrix", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CS8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CS9-1", "uniprot_id": [ { "id": "RAD50_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CS9", "type": "external" } ], "mass": 156207.0, "length": 1351, "protein_name": "DNA repair protein RAD50", "gene_name": "rad50", "organism": "Cellular slime mold", "refseq_name": "DNA recombination/repair protein", "refseq_ac": [ { "id": "XP_629462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629462", "type": "external" } ], "gene_names_uniprotkb": "rad50; DDB_G0292786", "gene_names_refseq": "rad50", "protein_names_uniprotkb": "DNA repair protein RAD50; 3.6.-.-; DNA recombination/repair protein", "protein_names_refseq": "DNA recombination/repair protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292786); (R-DDI-2559586); (R-DDI-5685938); (R-DDI-5693548); (R-DDI-5693565); (R-DDI-5693607); (R-DDI-5693616)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. The MRN complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11, to initiate end resection, which is required for single-strand invasion and recombination (By similarity). Within the complex, RAD50 is both required to bind DNA ends and hold them in close proximity and regulate the activity of MRE11. RAD50 provides an ATP-dependent control of MRE11 by positioning DNA ends into the MRE11 active site: ATP-binding induces a large structural change from an open form with accessible MRE11 nuclease sites into a closed form (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0030870 Mre11 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006302 double-strand break repair;GO:0007004 telomere maintenance via telomerase;GO:0070192 chromosome organization involved in meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CS9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CT8-1", "uniprot_id": [ { "id": "KADB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CT8", "type": "external" } ], "mass": 26172.0, "length": 232, "protein_name": "Probable adenylate kinase B", "gene_name": "adkB", "organism": "Cellular slime mold", "refseq_name": "adenylate kinase", "refseq_ac": [ { "id": "XP_629490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629490", "type": "external" } ], "gene_names_uniprotkb": "adkB; DDB_G0292730", "gene_names_refseq": "adkB", "protein_names_uniprotkb": "Probable adenylate kinase B; 2.7.4.3; AK B; ATP-AMP transphosphorylase B; ATP:AMP phosphotransferase; Adenylate monophosphate kinase", "protein_names_refseq": "adenylate kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292730); (R-DDI-499943); (R-DDI-983231)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" } ], "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0046899 nucleoside triphosphate adenylate kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0046033 AMP metabolic process;GO:0009142 nucleoside triphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CU9-1", "uniprot_id": [ { "id": "DUS3L_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CU9", "type": "external" } ], "mass": 76229.0, "length": 671, "protein_name": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like", "gene_name": "dus3l", "organism": "Cellular slime mold", "refseq_name": "CCCH-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_629571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629571", "type": "external" } ], "gene_names_uniprotkb": "dus3l; DDB_G0292686", "gene_names_refseq": "dus3l", "protein_names_uniprotkb": "tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; 1.3.1.-; 1.3.1.89; mRNA-dihydrouridine synthase dus3l; tRNA-dihydrouridine synthase 3-like", "protein_names_refseq": "CCCH-type zinc finger-containing protein; tRNA-dihydrouridine synthase 3-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292686)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.-", "type": "external" }, { "id": "1.3.1.89", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.89", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0017150 tRNA dihydrouridine synthase activity;GO:0106414 mRNA dihydrouridine synthase activity;GO:0102265 tRNA-dihydrouridine47 synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CW7-1", "uniprot_id": [ { "id": "RTPR_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CW7", "type": "external" } ], "mass": 86008.0, "length": 758, "protein_name": "Probable adenosylcobalamin-dependent ribonucleoside-triphosphate reductase", "gene_name": "rtpR", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rtpR; DDB_G0292654", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable adenosylcobalamin-dependent ribonucleoside-triphosphate reductase; 1.17.4.2; RTPR", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292654)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.17.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.4.2", "type": "external" } ], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;GO:0031419 cobalamin binding;GO:0008998 ribonucleoside-triphosphate reductase (thioredoxin) activity", "go_cellular_component": "", "go_biological_process": "GO:0006260 DNA replication;GO:0009142 nucleoside triphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CX4-1", "uniprot_id": [ { "id": "Y5521_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CX4", "type": "external" } ], "mass": 102342.0, "length": 903, "protein_name": "E3 ubiquitin-protein ligase DDB_G0292642", "gene_name": "DDB_G0292642", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629545", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292642", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase DDB_G0292642; 2.3.2.31", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292642); (ddi:DDB_G0292706); (R-DDI-983168)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "E3 ubiquitin-protein ligase., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54CX5", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031090 organelle membrane;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CX4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CX6-1", "uniprot_id": [ { "id": "3HIDH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CX6", "type": "external" } ], "mass": 33936.0, "length": 321, "protein_name": "Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "hibA", "organism": "Cellular slime mold", "refseq_name": "3-hydroxyisobutyrate dehydrogenase", "refseq_ac": [ { "id": "XP_629544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629544", "type": "external" } ], "gene_names_uniprotkb": "hibA; DDB_G0292566", "gene_names_refseq": "hibA", "protein_names_uniprotkb": "Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial; 1.1.1.31; HIBADH", "protein_names_refseq": "3-hydroxyisobutyrate dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292566); (R-DDI-70895)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.31", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0008442 3-hydroxyisobutyrate dehydrogenase activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006574 L-valine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CY5-1", "uniprot_id": [ { "id": "FOLC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CY5", "type": "external" } ], "mass": 70637.0, "length": 626, "protein_name": "Putative folylpolyglutamate synthase", "gene_name": "folC", "organism": "Cellular slime mold", "refseq_name": "folylpolyglutamate synthase", "refseq_ac": [ { "id": "XP_629535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629535", "type": "external" } ], "gene_names_uniprotkb": "folC; DDB_G0292632", "gene_names_refseq": "folC", "protein_names_uniprotkb": "Putative folylpolyglutamate synthase; 6.3.2.17; FPGS; Folylpoly-gamma-glutamate synthetase; Tetrahydrofolate synthase; Tetrahydrofolylpolyglutamate synthase", "protein_names_refseq": "folylpolyglutamate synthase; tetrahydrofolylpolyglutamate synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292632); (R-DDI-196757)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Conversion of folates to polyglutamate derivatives., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.2.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004326 tetrahydrofolylpolyglutamate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54CY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54CY9-1", "uniprot_id": [ { "id": "MYLKD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54CY9", "type": "external" } ], "mass": 35691.0, "length": 313, "protein_name": "Probable myosin light chain kinase DDB_G0292624", "gene_name": "DDB_G0292624", "organism": "Cellular slime mold", "refseq_name": "CAMK1 family protein kinase", "refseq_ac": [ { "id": "XP_629531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629531", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292624", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable myosin light chain kinase DDB_G0292624; 2.7.11.18", "protein_names_refseq": "CAMK1 family protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292624)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18559084", "class_list": "", "function": "May phosphorylate a specific serine in the N-terminus of a myosin light chain., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.18", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004687 myosin light chain kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54CY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D04-1", "uniprot_id": [ { "id": "MDHB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D04", "type": "external" } ], "mass": 37648.0, "length": 348, "protein_name": "Probable malate dehydrogenase 2, mitochondrial", "gene_name": "mdhB", "organism": "Cellular slime mold", "refseq_name": "malate dehydrogenase", "refseq_ac": [ { "id": "XP_629516", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629516", "type": "external" } ], "gene_names_uniprotkb": "mdhB; DDB_G0292600", "gene_names_refseq": "mdhB", "protein_names_uniprotkb": "Probable malate dehydrogenase 2, mitochondrial; 1.1.1.37", "protein_names_refseq": "malate dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292600)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the reversible oxidation of malate to oxaloacetate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" } ], "go_molecular_function": "GO:0030060 L-malate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006107 oxaloacetate metabolic process;GO:0019674 NAD+ metabolic process;GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54D04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D07-1", "uniprot_id": [ { "id": "CY1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D07", "type": "external" } ], "mass": 30536.0, "length": 275, "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "cyc1", "organism": "Cellular slime mold", "refseq_name": "cytochrome c1", "refseq_ac": [ { "id": "XP_629513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629513", "type": "external" } ], "gene_names_uniprotkb": "cyc1; DDB_G0292594", "gene_names_refseq": "cyc1", "protein_names_uniprotkb": "Cytochrome c1, heme protein, mitochondrial; 7.1.1.8; Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Cytochrome c-1", "protein_names_refseq": "cytochrome c1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292594); (R-DDI-611105)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.24.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.64", "type": "external" }, { "id": "7.1.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.8", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0008121 quinol-cytochrome-c reductase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54D07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D08-1", "uniprot_id": [ { "id": "LST8_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D08", "type": "external" } ], "mass": 33481.0, "length": 304, "protein_name": "Protein LST8 homolog", "gene_name": "lst8", "organism": "Cellular slime mold", "refseq_name": "WD40 repeat-containing protein", "refseq_ac": [ { "id": "XP_629512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629512", "type": "external" } ], "gene_names_uniprotkb": "lst8; DDB_G0292592", "gene_names_refseq": "lst8", "protein_names_uniprotkb": "Protein LST8 homolog; Lethal with sec thirteen 8 protein", "protein_names_refseq": "WD40 repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292592); (R-DDI-1257604); (R-DDI-1632852); (R-DDI-165159); (R-DDI-166208); (R-DDI-3371571); (R-DDI-380972); (R-DDI-389357); (R-DDI-5218920); (R-DDI-5628897); (R-DDI-6804757); (R-DDI-8943724); (R-DDI-9639288); (R-DDI-9856530)", "pathway_count": 14, "publication_count": 2, "publication_id_list": "15875012;16079174", "class_list": "", "function": "Plays a role in regulation of adenylate cyclase and protein kinase B (PKB) activation during aggregation. Involved in both chemotaxis and signal relay., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019887 protein kinase regulator activity;GO:0010856 adenylate cyclase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031252 cell leading edge;GO:0005776 autophagosome;GO:0031931 TORC1 complex;GO:0031932 TORC2 complex", "go_biological_process": "GO:0051702 biological process involved in interaction with symbiont;GO:0032956 regulation of actin cytoskeleton organization;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0031929 TOR signaling;GO:0050765 negative regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54D08-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D13-1", "uniprot_id": [ { "id": "RNH2A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D13", "type": "external" } ], "mass": 33083.0, "length": 289, "protein_name": "Ribonuclease H2 subunit A", "gene_name": "rnaseh2A", "organism": "Cellular slime mold", "refseq_name": "RNase H2 subunit A", "refseq_ac": [ { "id": "XP_629507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629507", "type": "external" } ], "gene_names_uniprotkb": "rnaseh2A; DDB_G0292584", "gene_names_refseq": "rnaseh2a", "protein_names_uniprotkb": "Ribonuclease H2 subunit A; 3.1.26.4; RNase H2 subunit A", "protein_names_refseq": "RNase H2 subunit A; ribonuclease H2 subunit A", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292584)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0004523 RNA-DNA hybrid ribonuclease activity", "go_cellular_component": "GO:0032299 ribonuclease H2 complex", "go_biological_process": "GO:0006298 mismatch repair;GO:0016070 RNA metabolic process;GO:0043137 DNA replication, removal of RNA primer", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54D13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D44-1", "uniprot_id": [ { "id": "PKS42_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D44", "type": "external" } ], "mass": 302636.0, "length": 2655, "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "organism": "Cellular slime mold", "refseq_name": "beta-ketoacyl synthase family protein", "refseq_ac": [ { "id": "XP_629652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629652", "type": "external" } ], "gene_names_uniprotkb": "pks42; DDB_G0292544", "gene_names_refseq": "pks42", "protein_names_uniprotkb": "Probable polyketide synthase 42; 2.3.1.-; dipks42", "protein_names_refseq": "beta-ketoacyl synthase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292544)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17660200", "class_list": "", "function": "Probable polyketide synthase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54D44-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D58-1", "uniprot_id": [ { "id": "APC7_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D58", "type": "external" } ], "mass": 66851.0, "length": 580, "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "anapc7", "organism": "Cellular slime mold", "refseq_name": "anaphase promoting complex subunit 7", "refseq_ac": [ { "id": "XP_629638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629638", "type": "external" } ], "gene_names_uniprotkb": "anapc7; DDB_G0292470; apc7", "gene_names_refseq": "anapc7", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 7; APC7", "protein_names_refseq": "anaphase promoting complex subunit 7", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292470)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140767 enzyme-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0051301 cell division;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54D58-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D73-1", "uniprot_id": [ { "id": "FHBB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D73", "type": "external" } ], "mass": 48206.0, "length": 423, "protein_name": "Flavohemoprotein B", "gene_name": "fhbB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629623", "type": "external" } ], "gene_names_uniprotkb": "fhbB; DDB_G0292380", "gene_names_refseq": "fhbB", "protein_names_uniprotkb": "Flavohemoprotein B; 1.14.12.17; DdFHb; Flavohemoglobin B; Hemoglobin-like protein B; NO oxygenase B; NOD B; Nitric oxide dioxygenase B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292380)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10791894;15875012;16926386", "class_list": "", "function": "In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities. However, all these reactions are much lower than NOD activity (By similarity)., [UniProtKB]; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the cell from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9UAG6", "ec_number_list": [ { "id": "1.14.12.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.12.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0071949 FAD binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0071333 cellular response to glucose stimulus;GO:0009636 response to toxic substance;GO:0071500 cellular response to nitrosative stress;GO:0046210 nitric oxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54D73-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D75-1", "uniprot_id": [ { "id": "Y2550_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D75", "type": "external" } ], "mass": 158111.0, "length": 1397, "protein_name": "Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550", "gene_name": "DDB_G0292550", "organism": "Cellular slime mold", "refseq_name": "CDK family protein kinase", "refseq_ac": [ { "id": "XP_629621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629621", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292550", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550; 2.7.11.22", "protein_names_refseq": "CDK family protein kinase; protein kinase, CMGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292550)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:1901987 regulation of cell cycle phase transition", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54D75-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54D84-1", "uniprot_id": [ { "id": "TRIA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54D84", "type": "external" } ], "mass": 79148.0, "length": 697, "protein_name": "Trishanku", "gene_name": "triA", "organism": "Cellular slime mold", "refseq_name": "BTB/POZ domain-containing protein", "refseq_ac": [ { "id": "XP_629612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629612", "type": "external" } ], "gene_names_uniprotkb": "triA; 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Probably involved in vesicular traffic (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0140220 pathogen-containing vacuole", "go_biological_process": "GO:0015031 protein transport;GO:0030100 regulation of endocytosis;GO:0016192 vesicle-mediated transport;GO:0032482 Rab protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DA9-1", "uniprot_id": [ { "id": "HACL1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DA9", "type": "external" } ], "mass": 63165.0, "length": 580, "protein_name": "2-hydroxyacyl-CoA lyase 1", "gene_name": "hacl1", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629587", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629587", "type": "external" } ], "gene_names_uniprotkb": "hacl1; DDB_G0292402", "gene_names_refseq": "", "protein_names_uniprotkb": "2-hydroxyacyl-CoA lyase 1; 2-HPCL; 2-hydroxyphytanoyl-CoA lyase; 4.1.2.63", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292402); (R-DDI-389599); (R-DDI-9033241)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids and the shortening of 2-hydroxy long-chain fatty acids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "4.2.1.119", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.119", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "1.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.4", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030976 thiamine pyrophosphate binding;GO:0016830 carbon-carbon lyase activity;GO:0106359 2-hydroxyacyl-CoA lyase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0001561 fatty acid alpha-oxidation;GO:0006625 protein targeting to peroxisome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DC8-1", "uniprot_id": [ { "id": "Y2350_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DC8", "type": "external" } ], "mass": 138962.0, "length": 1224, "protein_name": "Probable serine/threonine-protein kinase DDB_G0292350", "gene_name": "DDB_G0292350", "organism": "Cellular slime mold", "refseq_name": "protein kinase, STE group", "refseq_ac": [ { "id": "XP_629713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629713", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292350", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0292350; 2.7.11.1", "protein_names_refseq": "protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292350); (R-DDI-75153)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DC8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DD0-1", "uniprot_id": [ { "id": "AMPD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DD0", "type": "external" } ], "mass": 90954.0, "length": 790, "protein_name": "AMP deaminase", "gene_name": "amdA", "organism": "Cellular slime mold", "refseq_name": "AMP deaminase", "refseq_ac": [ { "id": "XP_629711", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629711", "type": "external" } ], "gene_names_uniprotkb": "amdA; DDB_G0292266", "gene_names_refseq": "amdA", "protein_names_uniprotkb": "AMP deaminase; 3.5.4.6; AMPD1", "protein_names_refseq": "AMP deaminase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292266); (R-DDI-6798695); (R-DDI-74217)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "11784104;15875012;17259634;1916064", "class_list": "", "function": "Catalyzes the conversion of adenosine monophosphate (AMP) to inosine monophosphate (IMP) and ammonia (NH4(+)) (PubMed:11784104, PubMed:1916064). Participates in the regulation of the adenylated nucleotide pool and the interconversion to guanylated nucleotides during early morphodifferentiation (PubMed:17259634, PubMed:1916064)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9NGX0", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003876 AMP deaminase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0001708 cell fate specification;GO:0046033 AMP metabolic process;GO:0006188 IMP biosynthetic process;GO:0032264 IMP salvage;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54DD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DD3-1", "uniprot_id": [ { "id": "GCST_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DD3", "type": "external" } ], "mass": 44247.0, "length": 403, "protein_name": "Aminomethyltransferase, mitochondrial", "gene_name": "gcvT", "organism": "Cellular slime mold", "refseq_name": "glycine cleavage system T-protein", "refseq_ac": [ { "id": "XP_629708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629708", "type": "external" } ], "gene_names_uniprotkb": "gcvT; DDB_G0292326", "gene_names_refseq": "gcvT", "protein_names_uniprotkb": "Aminomethyltransferase, mitochondrial; 2.1.2.10; GCVT; Glycine cleavage system T protein", "protein_names_refseq": "glycine cleavage system T-protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292326); (R-DDI-6783984)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "The glycine cleavage system catalyzes the degradation of glycine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.10", "type": "external" } ], "go_molecular_function": "GO:0008483 transaminase activity;GO:0004047 aminomethyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005960 glycine cleavage complex", "go_biological_process": "GO:0019464 glycine decarboxylation via glycine cleavage system", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DE8-1", "uniprot_id": [ { "id": "PSNB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DE8", "type": "external" } ], "mass": 52559.0, "length": 473, "protein_name": "Presenilin-B", "gene_name": "psenB", "organism": "Cellular slime mold", "refseq_name": "peptidase A22 family protein", "refseq_ac": [ { "id": "XP_629693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629693", "type": "external" } ], "gene_names_uniprotkb": "psenB; DDB_G0292310", "gene_names_refseq": "psenB", "protein_names_uniprotkb": "Presenilin-B; 3.4.23.-; PS-B", "protein_names_refseq": "peptidase A22 family protein; presenilin family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292310); (R-DDI-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Requires the other members of the gamma-secretase complex to have a protease activity (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.2.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.25", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0070765 gamma-secretase complex", "go_biological_process": "GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0016485 protein processing;GO:0006909 phagocytosis;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DE8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DF1-1", "uniprot_id": [ { "id": "ATPG_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DF1", "type": "external" } ], "mass": 33629.0, "length": 306, "protein_name": "ATP synthase F(1) complex subunit gamma, mitochondrial", "gene_name": "atp5f1c", "organism": "Cellular slime mold", "refseq_name": "ATP synthase gamma chain", "refseq_ac": [ { "id": "XP_629690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629690", "type": "external" } ], "gene_names_uniprotkb": "atp5f1c; DDB_G0292306; atp5C1", "gene_names_refseq": "atp5C1", "protein_names_uniprotkb": "ATP synthase F(1) complex subunit gamma, mitochondrial; ATP synthase F1 subunit gamma; F-ATPase gamma subunit", "protein_names_refseq": "ATP synthase gamma chain; F1-ATPase gamma subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292306); (R-DDI-9837999)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "Subunit gamma, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the central stalk subunit delta, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045335 phagocytic vesicle;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DF1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DF2-1", "uniprot_id": [ { "id": "MRKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DF2", "type": "external" } ], "mass": 119681.0, "length": 1060, "protein_name": "Probable serine/threonine-protein kinase MARK-A", "gene_name": "mrkA", "organism": "Cellular slime mold", "refseq_name": "CAMKL family protein kinase", "refseq_ac": [ { "id": "XP_629689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629689", "type": "external" } ], "gene_names_uniprotkb": "mrkA; DDB_G0292304", "gene_names_refseq": "mrkA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase MARK-A; 2.7.11.1", "protein_names_refseq": "CAMKL family protein kinase; MARK subfamily protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292304); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DF2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DF9-1", "uniprot_id": [ { "id": "DCUP_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DF9", "type": "external" } ], "mass": 40871.0, "length": 364, "protein_name": "Uroporphyrinogen decarboxylase", "gene_name": "hemE", "organism": "Cellular slime mold", "refseq_name": "uroporphyrinogen decarboxylase", "refseq_ac": [ { "id": "XP_629682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629682", "type": "external" } ], "gene_names_uniprotkb": "hemE; DDB_G0292294; urod", "gene_names_refseq": "hemE", "protein_names_uniprotkb": "Uroporphyrinogen decarboxylase; 4.1.1.37; UPD; URO-D", "protein_names_refseq": "uroporphyrinogen decarboxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292294); (R-DDI-189451)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.37", "type": "external" } ], "go_molecular_function": "GO:0004853 uroporphyrinogen decarboxylase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DG0-1", "uniprot_id": [ { "id": "Q54DG0_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DG0", "type": "external" } ], "mass": 238317.0, "length": 2129, "protein_name": "Chromatin-remodeling ATPase INO80", "gene_name": "ino80", "organism": "Cellular slime mold", "refseq_name": "CHR group protein", "refseq_ac": [ { "id": "XP_629681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629681", "type": "external" } ], "gene_names_uniprotkb": "ino80; DDB_G0292358", "gene_names_refseq": "ino80", "protein_names_uniprotkb": "Chromatin-remodeling ATPase INO80; 3.6.4.-", "protein_names_refseq": "CHR group protein; DEAD/DEAH box helicase domain-containing protein; SNF2-related domain-containing protein; helicase, C-terminal domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292358)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0042393 histone binding", "go_cellular_component": "GO:0031011 Ino80 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DG0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DG1-1", "uniprot_id": [ { "id": "ALDH3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DG1", "type": "external" } ], "mass": 52563.0, "length": 470, "protein_name": "Aldehyde dehydrogenase family 3 comG", "gene_name": "comG", "organism": "Cellular slime mold", "refseq_name": "aldehyde dehydrogenase", "refseq_ac": [ { "id": "XP_629680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629680", "type": "external" } ], "gene_names_uniprotkb": "comG; DDB_G0292270", "gene_names_refseq": "comG", "protein_names_uniprotkb": "Aldehyde dehydrogenase family 3 comG; 1.2.1.5; Communication mutant protein G", "protein_names_refseq": "aldehyde dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292270); (R-DDI-211945); (R-DDI-389599); (R-DDI-6798695); (R-DDI-9603798); (R-DDI-9609523); (R-DDI-9845614)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "12871696;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86MX3", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0004028 3-chloroallyl aldehyde dehydrogenase activity;GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0033721 aldehyde dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0006081 aldehyde metabolic process;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DG1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DH8-1", "uniprot_id": [ { "id": "TAF1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DH8", "type": "external" } ], "mass": 259629.0, "length": 2310, "protein_name": "Transcription initiation factor TFIID subunit 1", "gene_name": "taf1", "organism": "Cellular slime mold", "refseq_name": "HAF group protein", "refseq_ac": [ { "id": "XP_629749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629749", "type": "external" } ], "gene_names_uniprotkb": "taf1; DDB_G0292242; TFIID1", "gene_names_refseq": "taf1", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 1", "protein_names_refseq": "HAF group protein; TAF1 family protein kinase; TFIID subunit; bromodomain-containing protein; protein kinase, Atypical group; transcription initiation factor TFIID subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292242); (R-DDI-674695); (R-DDI-73776); (R-DDI-73779); (R-DDI-75953); (R-DDI-76042)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "15875012;16596165", "class_list": "", "function": "May be a component of the TFIID basal transcription factor complex., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017025 TBP-class protein binding;GO:0004402 histone acetyltransferase activity;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DH8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DK1-1", "uniprot_id": [ { "id": "SQOR_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DK1", "type": "external" } ], "mass": 50145.0, "length": 452, "protein_name": "Sulfide:quinone oxidoreductase, mitochondrial", "gene_name": "sqor", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629726", "type": "external" } ], "gene_names_uniprotkb": "sqor; DDB_G0292250; sqrdl", "gene_names_refseq": "sqrdl", "protein_names_uniprotkb": "Sulfide:quinone oxidoreductase, mitochondrial; 1.8.5.8", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292250)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.5.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.8", "type": "external" } ], "go_molecular_function": "GO:0070224 sulfide:quinone oxidoreductase activity;GO:0071949 FAD binding;GO:0048038 quinone binding;GO:0106436 glutathione-dependent sulfide quinone oxidoreductase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0042762 regulation of sulfur metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DK3-1", "uniprot_id": [ { "id": "CDC7_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DK3", "type": "external" } ], "mass": 120073.0, "length": 1061, "protein_name": "Probable serine/threonine-protein kinase cdc7", "gene_name": "cdc7", "organism": "Cellular slime mold", "refseq_name": "CDC7 family protein kinase", "refseq_ac": [ { "id": "XP_629869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629869", "type": "external" } ], "gene_names_uniprotkb": "cdc7; DDB_G0292152", "gene_names_refseq": "cdc7", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase cdc7; 2.7.11.1; Cell division control protein 7", "protein_names_refseq": "CDC7 family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292152); (R-DDI-4086398); (R-DDI-5687128)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DK3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DK4-1", "uniprot_id": [ { "id": "AK1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DK4", "type": "external" } ], "mass": 154085.0, "length": 1352, "protein_name": "Alpha-protein kinase 1", "gene_name": "ak1", "organism": "Cellular slime mold", "refseq_name": "Alpha kinase family protein", "refseq_ac": [ { "id": "XP_629868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629868", "type": "external" } ], "gene_names_uniprotkb": "ak1; DDB_G0292150", "gene_names_refseq": "ak1", "protein_names_uniprotkb": "Alpha-protein kinase 1; 2.7.11.-; AK1", "protein_names_refseq": "Alpha kinase family protein; Arf GTPase activating protein; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292150)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;15987738", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016905 myosin heavy chain kinase activity", "go_cellular_component": "GO:0005826 actomyosin contractile ring", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0000281 mitotic cytokinesis;GO:0031037 myosin II filament disassembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DK4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DM0-1", "uniprot_id": [ { "id": "HATC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DM0", "type": "external" } ], "mass": 13867.0, "length": 119, "protein_name": "Hisactophilin-3", "gene_name": "hatC", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_629852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629852", "type": "external" } ], "gene_names_uniprotkb": "hatC; DDB_G0292136", "gene_names_refseq": "hatC", "protein_names_uniprotkb": "Hisactophilin-3; Histidine-rich actin-binding protein 3", "protein_names_refseq": "actin binding protein; hisactophilin III", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292136)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May act as an intracellular pH sensor that links chemotactic signals to responses in the microfilament system of the cells by nucleating actin polymerization or stabilizing the filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005504 fatty acid binding;GO:0030674 protein-macromolecule adaptor activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0030041 actin filament polymerization;GO:0010447 response to acidic pH;GO:0006972 hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DM3-1", "uniprot_id": [ { "id": "Q54DM3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DM3", "type": "external" } ], "mass": 141526.0, "length": 1259, "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "blm", "organism": "Cellular slime mold", "refseq_name": "ATP-dependent DNA helicase RecQ family protein", "refseq_ac": [ { "id": "XP_629849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629849", "type": "external" } ], "gene_names_uniprotkb": "blm; DDB_G0292130", "gene_names_refseq": "blm", "protein_names_uniprotkb": "RecQ-like DNA helicase BLM; 5.6.2.4", "protein_names_refseq": "ATP-dependent DNA helicase RecQ family protein; Bloom syndrome protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292130); (R-DDI-3108214); (R-DDI-5685938); (R-DDI-5693607); (R-DDI-5693616)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DM3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DM4-1", "uniprot_id": [ { "id": "Q54DM4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DM4", "type": "external" } ], "mass": 178617.0, "length": 1569, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "DDB_G0292128", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629848", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0292128", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292128); (R-DDI-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DM4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DM7-1", "uniprot_id": [ { "id": "PSA2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DM7", "type": "external" } ], "mass": 25666.0, "length": 232, "protein_name": "Proteasome subunit alpha type-2", "gene_name": "psmA2", "organism": "Cellular slime mold", "refseq_name": "20S proteasome subunit alpha-2", "refseq_ac": [ { "id": "XP_629845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629845", "type": "external" } ], "gene_names_uniprotkb": "psmA2; DDB_G0292122", "gene_names_refseq": "psmA2", "protein_names_uniprotkb": "Proteasome subunit alpha type-2", "protein_names_refseq": "20S proteasome subunit alpha-2; proteasome subunit alpha type 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292122); (R-DDI-1236974); (R-DDI-1236978); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-187577); (R-DDI-2467813); (R-DDI-349425); (R-DDI-382556); (R-DDI-450408); (R-DDI-4641258); (R-DDI-5632684); (R-DDI-5658442); (R-DDI-5687128); (R-DDI-5689603); (R-DDI-5689880); (R-DDI-6798695); (R-DDI-68949); (R-DDI-69017); (R-DDI-69601); (R-DDI-75815); (R-DDI-8854050); (R-DDI-8948751); (R-DDI-8951664); (R-DDI-9755511); (R-DDI-983168); (R-DDI-9907900); (R-DDI-9912633); (R-DDI-9929491); (R-DDI-9954709)", "pathway_count": 31, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DM7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DM9-1", "uniprot_id": [ { "id": "ALG11_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DM9", "type": "external" } ], "mass": 57519.0, "length": 505, "protein_name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "gene_name": "alg11", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629843", "type": "external" } ], "gene_names_uniprotkb": "alg11; DDB_G0292118", "gene_names_refseq": "alg11", "protein_names_uniprotkb": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; 2.4.1.131; Asparagine-linked glycosylation protein 11 homolog; Glycolipid 2-alpha-mannosyltransferase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292118)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "glycogene;glycosyltransferase", "function": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.131", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.131", "type": "external" } ], "go_molecular_function": "GO:0004377 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0006488 dolichol-linked oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DN6-1", "uniprot_id": [ { "id": "GALK_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DN6", "type": "external" } ], "mass": 56128.0, "length": 501, "protein_name": "Galactokinase", "gene_name": "galK", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629836", "type": "external" } ], "gene_names_uniprotkb": "galK; DDB_G0292112", "gene_names_refseq": "galK", "protein_names_uniprotkb": "Galactokinase; 2.7.1.6; Galactose kinase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292112)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004335 galactokinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019388 galactose catabolic process;GO:0006012 galactose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DN6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DP1-1", "uniprot_id": [ { "id": "TKRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DP1", "type": "external" } ], "mass": 37433.0, "length": 334, "protein_name": "Probable 2-ketogluconate reductase", "gene_name": "tkrA", "organism": "Cellular slime mold", "refseq_name": "2-keto-D-gluconate reductase", "refseq_ac": [ { "id": "XP_629831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629831", "type": "external" } ], "gene_names_uniprotkb": "tkrA; DDB_G0292104", "gene_names_refseq": "tkrA", "protein_names_uniprotkb": "Probable 2-ketogluconate reductase; 1.1.1.215; 2-ketoaldonate reductase; 2KR", "protein_names_refseq": "2-keto-D-gluconate reductase; gluconate 2-dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292104); (R-DDI-389661)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of 2,5-diketo-D-gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2-keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.215", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.215", "type": "external" } ], "go_molecular_function": "GO:0016618 hydroxypyruvate reductase [NAD(P)H] activity;GO:0030267 glyoxylate reductase (NADPH) activity;GO:0051287 NAD binding;GO:0008873 gluconate 2-dehydrogenase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019521 D-gluconate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DR1-1", "uniprot_id": [ { "id": "FDFT_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DR1", "type": "external" } ], "mass": 47504.0, "length": 416, "protein_name": "Squalene synthase", "gene_name": "fdfT", "organism": "Cellular slime mold", "refseq_name": "farnesyl-diphosphate farnesyltransferase", "refseq_ac": [ { "id": "XP_629811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629811", "type": "external" } ], "gene_names_uniprotkb": "fdfT; DDB_G0292072", "gene_names_refseq": "fdfT", "protein_names_uniprotkb": "Squalene synthase; 2.5.1.21; FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; SQS; SS", "protein_names_refseq": "farnesyl-diphosphate farnesyltransferase; squalene synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292072); (R-DDI-9969896)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.21", "type": "external" } ], "go_molecular_function": "GO:0051996 squalene synthase [NAD(P)H] activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006695 cholesterol biosynthetic process;GO:0008299 isoprenoid biosynthetic process;GO:0045338 farnesyl diphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DS8-1", "uniprot_id": [ { "id": "SEC13_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DS8", "type": "external" } ], "mass": 33602.0, "length": 301, "protein_name": "Protein SEC13 homolog", "gene_name": "sec13", "organism": "Cellular slime mold", "refseq_name": "WD40 repeat-containing protein", "refseq_ac": [ { "id": "XP_629794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629794", "type": "external" } ], "gene_names_uniprotkb": "sec13; DDB_G0292052", "gene_names_refseq": "sec13", "protein_names_uniprotkb": "Protein SEC13 homolog; GATOR complex protein SEC13", "protein_names_refseq": "WD40 repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292052); (R-DDI-204005); (R-DDI-9639288)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway., [UniProtKB]; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005643 nuclear pore;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0032008 positive regulation of TOR signaling;GO:0051028 mRNA transport;GO:0090114 COPII-coated vesicle budding;GO:0032527 protein exit from endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DT1-1", "uniprot_id": [ { "id": "ABCA9_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DT1", "type": "external" } ], "mass": 96318.0, "length": 845, "protein_name": "ABC transporter A family member 9", "gene_name": "abcA9", "organism": "Cellular slime mold", "refseq_name": "ABC transporter A family protein", "refseq_ac": [ { "id": "XP_629791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629791", "type": "external" } ], "gene_names_uniprotkb": "abcA9; DDB_G0291980; abcA12", "gene_names_refseq": "abcA9", "protein_names_uniprotkb": "ABC transporter A family member 9; ABC transporter ABCA.9", "protein_names_refseq": "ABC transporter A family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291980); (R-DDI-1369062); (R-DDI-2453902); (R-DDI-382556); (R-DDI-5683826); (R-DDI-6798695); (R-DDI-8963896)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "12456012;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T5Z8;Q8T6I8", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006869 lipid transport;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54DT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DT8-1", "uniprot_id": [ { "id": "PPOX_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DT8", "type": "external" } ], "mass": 59681.0, "length": 532, "protein_name": "Protoporphyrinogen oxidase", "gene_name": "ppox", "organism": "Cellular slime mold", "refseq_name": "protoporphyrinogen oxidase", "refseq_ac": [ { "id": "XP_629784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629784", "type": "external" } ], "gene_names_uniprotkb": "ppox; DDB_G0292040; hemG", "gene_names_refseq": "hemG", "protein_names_uniprotkb": "Protoporphyrinogen oxidase; 1.3.3.4; PPO", "protein_names_refseq": "protoporphyrinogen oxidase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292040); (R-DDI-189451)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.4", "type": "external" } ], "go_molecular_function": "GO:0004729 oxygen-dependent protoporphyrinogen oxidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0048870 cell motility;GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DW4-1", "uniprot_id": [ { "id": "Q54DW4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DW4", "type": "external" } ], "mass": 149937.0, "length": 1350, "protein_name": "Pleckstrin domain-containing protein", "gene_name": "xacA", "organism": "Cellular slime mold", "refseq_name": "RhoGAP domain-containing protein", "refseq_ac": [ { "id": "XP_629758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629758", "type": "external" } ], "gene_names_uniprotkb": "xacA; DDB_G0291978", "gene_names_refseq": "xacA", "protein_names_uniprotkb": "Pleckstrin domain-containing protein", "protein_names_refseq": "RhoGAP domain-containing protein; RhoGEF domain-containing protein; SH3 domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291978); (R-DDI-193648); (R-DDI-9013149)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0032483 regulation of Rab protein signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0035556 intracellular signal transduction;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DW4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DX7-1", "uniprot_id": [ { "id": "TAZ_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DX7", "type": "external" } ], "mass": 32784.0, "length": 285, "protein_name": "Taffazin", "gene_name": "taz", "organism": "Cellular slime mold", "refseq_name": "phospholipid/glycerol acyltransferase domain-containing protein", "refseq_ac": [ { "id": "XP_629919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629919", "type": "external" } ], "gene_names_uniprotkb": "taz; DDB_G0291922", "gene_names_refseq": "taz", "protein_names_uniprotkb": "Taffazin; 1-acylglycerophosphocholine O-acyltransferase; 2.3.1.-; Taz", "protein_names_refseq": "phospholipid/glycerol acyltransferase domain-containing protein; tafazzin family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291922); (R-DDI-1268020); (R-DDI-1482798)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acyltransferase required to remodel newly synthesized phospholipid cardiolipin (1',3'-bis-[1,2-diacyl-sn-glycero-3-phospho]-glycerol or CL), a key component of the mitochondrial inner membrane, with tissue specific acyl chains necessary for adequate mitochondrial function (By similarity). Its role in cellular physiology is to improve mitochondrial performance (By similarity). CL is critical for the coassembly of lipids and proteins in mitochondrial membranes, for instance, remodeling of the acyl groups of CL in the mitochondrial inner membrane affects the assembly and stability of respiratory chain complex IV and its supercomplex forms (By similarity). Catalyzes the transacylation between phospholipids and lysophospholipids, with the highest rate being between phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) and CL. Catalyzes both 1-acyl-sn-glycero-3-phosphocholine (lysophosphatidylcholine or LPC) reacylation and PC-CL transacylation, that means, it exchanges acyl groups between CL and PC by a combination of forward and reverse transacylations. Also catalyzes transacylations between other phospholipids such as phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) and CL, between PC and PE, and between PC and phosphatidate (1,2-diacyl-sn-glycero-3-phosphate or PA), although at lower rate. Not regiospecific, it transfers acyl groups into any of the sn-1 and sn-2 positions of the monolysocardiolipin (MLCL), which is an important prerequisite for uniformity and symmetry in CL acyl distribution. Cannot transacylate dilysocardiolipin (DLCL), thus, the role of MLCL is limited to that of an acyl acceptor. CoA-independent, it can reshuffle molecular species within a single phospholipid class. Redistributes fatty acids between MLCL, CL, and other lipids, which prolongs the half-life of CL. Its action is completely reversible, which allows for cyclic changes, such as fission and fusion or bending and flattening of the membrane. Hence, by contributing to the flexibility of the lipid composition, it plays an important role in the dynamics of mitochondria membranes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0035965 cardiolipin acyl-chain remodeling;GO:0007007 inner mitochondrial membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54DY1-1", "uniprot_id": [ { "id": "ARGJ_DICDI", "url": "https://www.uniprot.org/uniprot/Q54DY1", "type": "external" } ], "mass": 47724.0, "length": 442, "protein_name": "Arginine biosynthesis bifunctional protein ArgJ, mitochondrial", "gene_name": "argJ", "organism": "Cellular slime mold", "refseq_name": "N-acetylglutamate synthetase", "refseq_ac": [ { "id": "XP_629915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629915", "type": "external" } ], "gene_names_uniprotkb": "argJ; DDB_G0291916; arg7", "gene_names_refseq": "argJ", "protein_names_uniprotkb": "Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; AGS; N-acetylglutamate synthase; OATase; Ornithine acetyltransferase; Ornithine transacetylase", "protein_names_refseq": "N-acetylglutamate synthetase; amino-acid N-acetyltransferase; ornithine transacetylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291916)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.1", "type": "external" }, { "id": "2.3.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.35", "type": "external" } ], "go_molecular_function": "GO:0004042 L-glutamate N-acetyltransferase activity;GO:0004358 L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006526 L-arginine biosynthetic process;GO:0006592 ornithine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54DY1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54E04-1", "uniprot_id": [ { "id": "VATM_DICDI", "url": "https://www.uniprot.org/uniprot/Q54E04", "type": "external" } ], "mass": 93288.0, "length": 815, "protein_name": "Vacuolar proton translocating ATPase 100 kDa subunit", "gene_name": "vatM", "organism": "Cellular slime mold", "refseq_name": "vacuolar ATPase transmembrane subunit", "refseq_ac": [ { "id": "XP_629892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629892", "type": "external" } ], "gene_names_uniprotkb": "vatM; DDB_G0291858", "gene_names_refseq": "vatM", "protein_names_uniprotkb": "Vacuolar proton translocating ATPase 100 kDa subunit; Clathrin-coated vesicle/synaptic vesicle proton pump 100 kDa subunit; Vacuolar ATPase transmembrane subunit", "protein_names_refseq": "vacuolar ATPase transmembrane subunit; vacuolar proton ATPase 100-kDa subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291858); (R-DDI-1222556); (R-DDI-6798695); (R-DDI-77387); (R-DDI-917977); (R-DDI-9639288); (R-DDI-983712)", "pathway_count": 7, "publication_count": 5, "publication_id_list": "11956322;12082150;15875012;16926386;8743951", "class_list": "", "function": "Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. Required in both the contractile vacuole system and the endosomal/lysosomal system. Also required for cytosolic pH regulation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q23860", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0030670 phagocytic vesicle membrane;GO:0010008 endosome membrane;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0051453 regulation of intracellular pH;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54E04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54E29-1", "uniprot_id": [ { "id": "THG1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54E29", "type": "external" } ], "mass": 30110.0, "length": 256, "protein_name": "Probable tRNA(His) guanylyltransferase", "gene_name": "thg1", "organism": "Cellular slime mold", "refseq_name": "tRNA-histidine guanylyltransferase 1", "refseq_ac": [ { "id": "XP_629958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629958", "type": "external" } ], "gene_names_uniprotkb": "thg1; DDB_G0291830", "gene_names_refseq": "thg1", "protein_names_uniprotkb": "Probable tRNA(His) guanylyltransferase; 2.7.7.79; tRNA-histidine guanylyltransferase", "protein_names_refseq": "tRNA-histidine guanylyltransferase 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291830)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.79", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.79", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005525 GTP binding;GO:0008193 tRNA guanylyltransferase activity;GO:0097748 3'-5' RNA polymerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0008033 tRNA processing;GO:0006400 tRNA modification;GO:0099116 tRNA 5'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54E29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54E49-1", "uniprot_id": [ { "id": "DDX6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54E49", "type": "external" } ], "mass": 48171.0, "length": 423, "protein_name": "Probable ATP-dependent RNA helicase ddx6", "gene_name": "ddx6", "organism": "Cellular slime mold", "refseq_name": "DEAD/DEAH box helicase", "refseq_ac": [ { "id": "XP_629938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629938", "type": "external" } ], "gene_names_uniprotkb": "ddx6; DDB_G0291804", "gene_names_refseq": "ddx6", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase ddx6; 3.6.4.13; DEAD box protein 6", "protein_names_refseq": "DEAD/DEAH box helicase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291804); (R-DDI-430039)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "ATP-dependent RNA helicase which may be involved in mRNA turnover., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006397 mRNA processing;GO:0017148 negative regulation of translation;GO:0033962 P-body assembly;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54E49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ED3-1", "uniprot_id": [ { "id": "DNJA1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ED3", "type": "external" } ], "mass": 50096.0, "length": 459, "protein_name": "DnaJ homolog subfamily A member 1 homolog", "gene_name": "dnaja1", "organism": "Cellular slime mold", "refseq_name": "heat shock protein DnaJ family protein", "refseq_ac": [ { "id": "XP_635307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635307", "type": "external" } ], "gene_names_uniprotkb": "dnaja1; DDB_G0291568", "gene_names_refseq": "", "protein_names_uniprotkb": "DnaJ homolog subfamily A member 1 homolog", "protein_names_refseq": "heat shock protein DnaJ family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291568); (R-DDI-3371497)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Co-chaperone for Hsp70 family members. Plays a role in protein transport into mitochondria and in the regulation of apoptosis via its role as co-chaperone (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0051082 unfolded protein binding;GO:0001671 ATPase activator activity;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0034605 cellular response to heat;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54ED3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EF2-1", "uniprot_id": [ { "id": "ANM1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EF2", "type": "external" } ], "mass": 39121.0, "length": 341, "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "prmt1", "organism": "Cellular slime mold", "refseq_name": "protein arginine methyltransferase", "refseq_ac": [ { "id": "XP_635288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635288", "type": "external" } ], "gene_names_uniprotkb": "prmt1; DDB_G0291556", "gene_names_refseq": "prmt1", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 1; 2.1.1.319; Histone-arginine N-methyltransferase PRMT1", "protein_names_refseq": "protein arginine methyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291556); (R-DDI-3214858); (R-DDI-8876725); (R-DDI-9018519)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues present in proteins such as ribonucleoproteins and histones., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0008170 N-methyltransferase activity;GO:0016274 protein-arginine N-methyltransferase activity;GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054 histone methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006406 mRNA export from nucleus;GO:0006355 regulation of DNA-templated transcription;GO:0006479 protein methylation;GO:0045653 negative regulation of megakaryocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54EF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EG9-1", "uniprot_id": [ { "id": "Y1516_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EG9", "type": "external" } ], "mass": 112249.0, "length": 965, "protein_name": "Probable serine/threonine-protein kinase DDB_G0291516", "gene_name": "DDB_G0291516", "organism": "Cellular slime mold", "refseq_name": "ankyrin repeat-containing protein", "refseq_ac": [ { "id": "XP_635271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635271", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0291516", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0291516; 2.7.11.1", "protein_names_refseq": "ankyrin repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291516); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54EG9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EH1-1", "uniprot_id": [ { "id": "EPN_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EH1", "type": "external" } ], "mass": 75837.0, "length": 686, "protein_name": "Epsin", "gene_name": "epnA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635269", "type": "external" } ], "gene_names_uniprotkb": "epnA; DDB_G0291512", "gene_names_refseq": "epnA", "protein_names_uniprotkb": "Epsin", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291512); (R-DDI-8856825)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;18827012", "class_list": "", "function": "Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0030276 clathrin binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0072659 protein localization to plasma membrane;GO:0000281 mitotic cytokinesis;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54EH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EN4-1", "uniprot_id": [ { "id": "PDI2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EN4", "type": "external" } ], "mass": 57753.0, "length": 513, "protein_name": "Protein disulfide-isomerase 2", "gene_name": "pdi2", "organism": "Cellular slime mold", "refseq_name": "protein disulfide isomerase", "refseq_ac": [ { "id": "XP_635206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635206", "type": "external" } ], "gene_names_uniprotkb": "pdi2; DDB_G0291434", "gene_names_refseq": "pdi2", "protein_names_uniprotkb": "Protein disulfide-isomerase 2; 5.3.4.1; PDI2", "protein_names_refseq": "protein disulfide isomerase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291434); (R-DDI-901042)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" } ], "go_molecular_function": "GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0009617 response to bacterium;GO:0006457 protein folding;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54EN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ER6-1", "uniprot_id": [ { "id": "MTND_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ER6", "type": "external" } ], "mass": 17815.0, "length": 147, "protein_name": "Acireductone dioxygenase", "gene_name": "adi1", "organism": "Cellular slime mold", "refseq_name": "ARD/ARD' family protein", "refseq_ac": [ { "id": "XP_635174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635174", "type": "external" } ], "gene_names_uniprotkb": "adi1; DDB_G0291376", "gene_names_refseq": "adi1", "protein_names_uniprotkb": "Acireductone dioxygenase; 1.13.11.53; 1.13.11.54; ARD'; ARD; Acireductone dioxygenase (Fe(2+)-requiring); Acireductone dioxygenase (Ni(2+)-requiring); Fe-ARD; Ni-ARD", "protein_names_refseq": "ARD/ARD' family protein; acireductone dioxygenase 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291376); (R-DDI-1237112)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.13.11.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.54", "type": "external" }, { "id": "1.13.11.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.53", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0016491 oxidoreductase activity;GO:0016151 nickel cation binding;GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity;GO:0010308 acireductone dioxygenase (Ni2+-requiring) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine;GO:0006555 methionine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54ER6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ER9-1", "uniprot_id": [ { "id": "DIMB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ER9", "type": "external" } ], "mass": 68452.0, "length": 602, "protein_name": "Basic-leucine zipper transcription factor B", "gene_name": "dimB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635171", "type": "external" } ], "gene_names_uniprotkb": "dimB; DDB_G0291372", "gene_names_refseq": "dimB", "protein_names_uniprotkb": "Basic-leucine zipper transcription factor B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291372)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15875012;16396914;16410410;16819464", "class_list": "", "function": "Transcriptional regulator involved in DIF-1 signaling. DIF-1 (Differentiation Inducing Factor-1) is a signal molecule involved in the differentiation of pstO (prestalk-O) cells (By similarity). May be a direct activator of ecmA., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0042802 identical protein binding;GO:0000976 transcription cis-regulatory region binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0045184 establishment of protein localization;GO:0043069 negative regulation of programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54ER9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ES8-1", "uniprot_id": [ { "id": "YKT6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ES8", "type": "external" } ], "mass": 22771.0, "length": 202, "protein_name": "Putative synaptobrevin homolog YKT6", "gene_name": "ykt6", "organism": "Cellular slime mold", "refseq_name": "longin domain-containing protein", "refseq_ac": [ { "id": "XP_635162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635162", "type": "external" } ], "gene_names_uniprotkb": "ykt6; DDB_G0291656", "gene_names_refseq": "ykt6", "protein_names_uniprotkb": "Putative synaptobrevin homolog YKT6; 2.3.1.-; Putative prenylated SNARE protein ykt6", "protein_names_refseq": "longin domain-containing protein; v-SNARE family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291656)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport and in early/recycling endosome to TGN transport as part of a SNARE complex. Has a S-palmitoyl transferase activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016740 transferase activity;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0030670 phagocytic vesicle membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54ES8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ET0-1", "uniprot_id": [ { "id": "GRLE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ET0", "type": "external" } ], "mass": 89935.0, "length": 816, "protein_name": "Metabotropic glutamate receptor-like protein E", "gene_name": "grlE", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family 3 protein 5", "refseq_ac": [ { "id": "XP_635160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635160", "type": "external" } ], "gene_names_uniprotkb": "grlE; DDB_G0291356; GluPR", "gene_names_refseq": "grlE", "protein_names_uniprotkb": "Metabotropic glutamate receptor-like protein E; DdmGluPR; GABA-B receptor-like protein grlE", "protein_names_refseq": "G-protein-coupled receptor family 3 protein 5; GABA-B receptor protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291356); (R-DDI-418594); (R-DDI-420499); (R-DDI-977444)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "15875012;16527814;16672332;16735079;17501984;18559084", "class_list": "", "function": "May be involved in early development in cAMP sensing and subsequent chemotactic response. Probable receptor of GABA and glutamate, leading respectively to the induction or inhibition of SDF-2 formation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q1PDD1", "ec_number_list": [], "go_molecular_function": "GO:0004965 G protein-coupled GABA receptor activity;GO:0016595 glutamate binding;GO:0008066 glutamate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0038039 G protein-coupled receptor heterodimeric complex", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:0031152 aggregation involved in sorocarp development;GO:0043327 chemotaxis to cAMP;GO:1901261 regulation of sorocarp spore cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54ET0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ET2-1", "uniprot_id": [ { "id": "PSNA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ET2", "type": "external" } ], "mass": 69503.0, "length": 622, "protein_name": "Presenilin-A", "gene_name": "psenA", "organism": "Cellular slime mold", "refseq_name": "peptidase A22 family protein", "refseq_ac": [ { "id": "XP_635158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635158", "type": "external" } ], "gene_names_uniprotkb": "psenA; DDB_G0291352", "gene_names_refseq": "psenA", "protein_names_uniprotkb": "Presenilin-A; 3.4.23.-; PS-A", "protein_names_refseq": "peptidase A22 family protein; presenilin family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291352); (R-DDI-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Requires the other members of the gamma-secretase complex to have a protease activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.2.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.25", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0045121 membrane raft;GO:0005789 endoplasmic reticulum membrane;GO:0070765 gamma-secretase complex", "go_biological_process": "GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0016485 protein processing;GO:0006909 phagocytosis;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54ET2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EW0-1", "uniprot_id": [ { "id": "FRMA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EW0", "type": "external" } ], "mass": 129489.0, "length": 1154, "protein_name": "FERM domain-containing protein A", "gene_name": "frmA", "organism": "Cellular slime mold", "refseq_name": "FERM domain-containing protein", "refseq_ac": [ { "id": "XP_635130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635130", "type": "external" } ], "gene_names_uniprotkb": "frmA; DDB_G0291303", "gene_names_refseq": "frmA", "protein_names_uniprotkb": "FERM domain-containing protein A", "protein_names_refseq": "FERM domain-containing protein; talin family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291303)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;18349074;19002378", "class_list": "", "function": "Key regulator of adhesion dynamics, it acts as an anti-adhesive. Plays a critical role in the regulation of cell-cell adhesion, multi-cellular development and, in particular, the formation of the organising center known as the tip. Required for turnover of paxillin-adhesion sites during cell migration. Plays a major role in normal cell shape, cell-substrate adhesion and actin cytoskeleton organization., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0098609 cell-cell adhesion;GO:0046686 response to cadmium ion;GO:0022408 negative regulation of cell-cell adhesion;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54EW0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EW1-1", "uniprot_id": [ { "id": "GLYC2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EW1", "type": "external" } ], "mass": 53584.0, "length": 481, "protein_name": "Serine hydroxymethyltransferase 2", "gene_name": "shmt2", "organism": "Cellular slime mold", "refseq_name": "serine hydroxymethyltransferase", "refseq_ac": [ { "id": "XP_635129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635129", "type": "external" } ], "gene_names_uniprotkb": "shmt2; DDB_G0291652", "gene_names_refseq": "shmt2", "protein_names_uniprotkb": "Serine hydroxymethyltransferase 2; 2.1.2.1; Glycine hydroxymethyltransferase 2; SHMT 2; Serine methylase 2", "protein_names_refseq": "serine hydroxymethyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291652)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Interconversion of serine and glycine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004372 glycine hydroxymethyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0035999 tetrahydrofolate interconversion;GO:0046653 tetrahydrofolate metabolic process;GO:0019264 glycine biosynthetic process from serine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54EW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EW2-1", "uniprot_id": [ { "id": "Y9130_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EW2", "type": "external" } ], "mass": 120674.0, "length": 1080, "protein_name": "Putative bifunctional amine oxidase DDB_G0291301", "gene_name": "DDB_G0291301", "organism": "Cellular slime mold", "refseq_name": "amine oxidase", "refseq_ac": [ { "id": "XP_635128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635128", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0291301", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative bifunctional amine oxidase DDB_G0291301", "protein_names_refseq": "amine oxidase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291301); (R-DDI-8964208)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids. Metabolizes sarcosine, L-pipecolic acid and L-proline (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.3.1", "type": "external" }, { "id": "1.5.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.3.7", "type": "external" }, { "id": "1.4.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.2", "type": "external" } ], "go_molecular_function": "GO:0008115 sarcosine oxidase activity;GO:0050031 L-pipecolate oxidase activity;GO:0001716 L-amino-acid oxidase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0009063 amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54EW2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EW8-1", "uniprot_id": [ { "id": "DLDH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EW8", "type": "external" } ], "mass": 51794.0, "length": 488, "protein_name": "Dihydrolipoyl dehydrogenase, mitochondrial", "gene_name": "lpd", "organism": "Cellular slime mold", "refseq_name": "dihydrolipoamide dehydrogenase", "refseq_ac": [ { "id": "XP_635122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635122", "type": "external" } ], "gene_names_uniprotkb": "lpd; DDB_G0291648; bkdD; dld; odhC; pdhD", "gene_names_refseq": "lpd", "protein_names_uniprotkb": "Dihydrolipoyl dehydrogenase, mitochondrial; 1.8.1.4; Dihydrolipoamide dehydrogenase; Glycine cleavage system L protein", "protein_names_refseq": "dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD oxidoreductase; dihydrolipoyl dehydrogenase; glycine cleavage system L-protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291648); (R-DDI-6783984); (R-DDI-9853506); (R-DDI-9858328); (R-DDI-9859138); (R-DDI-9861559)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "15003488;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6S4V6", "ec_number_list": [ { "id": "2.3.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.12", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "1.8.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.4", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.2.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.4", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "1.2.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.-", "type": "external" }, { "id": "2.3.1.61", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.61", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0004148 dihydrolipoyl dehydrogenase (NADH) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle;GO:0045252 oxoglutarate dehydrogenase complex", "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006574 L-valine catabolic process;GO:0006552 L-leucine catabolic process;GO:0006546 glycine catabolic process;GO:0006550 L-isoleucine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54EW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EY0-1", "uniprot_id": [ { "id": "Q54EY0_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EY0", "type": "external" } ], "mass": 94242.0, "length": 823, "protein_name": "Polycystin cation channel PKD1/PKD2 domain-containing protein", "gene_name": "DDB_G0291275", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635110", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0291275", "gene_names_refseq": "", "protein_names_uniprotkb": "Polycystin cation channel PKD1/PKD2 domain-containing protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291275); (R-DDI-3295583); (R-DDI-917977)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0072345 NAADP-sensitive calcium-release channel activity;GO:0005261 monoatomic cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0032010 phagolysosome", "go_biological_process": "GO:0019722 calcium-mediated signaling;GO:0006874 intracellular calcium ion homeostasis;GO:0006909 phagocytosis;GO:0034405 response to fluid shear stress;GO:0044351 macropinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54EY0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54EY4-1", "uniprot_id": [ { "id": "DST3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54EY4", "type": "external" } ], "mass": 61799.0, "length": 562, "protein_name": "Serine/threonine-protein kinase dst3", "gene_name": "dst3", "organism": "Cellular slime mold", "refseq_name": "STE20 family protein kinase", "refseq_ac": [ { "id": "XP_635106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635106", "type": "external" } ], "gene_names_uniprotkb": "dst3; DDB_G0291267; dstC", "gene_names_refseq": "dst3", "protein_names_uniprotkb": "Serine/threonine-protein kinase dst3; 2.7.11.1", "protein_names_refseq": "STE20 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291267)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16842885", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007165 signal transduction;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54EY4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54F25-1", "uniprot_id": [ { "id": "CLN3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54F25", "type": "external" } ], "mass": 46557.0, "length": 421, "protein_name": "Battenin", "gene_name": "cln3", "organism": "Cellular slime mold", "refseq_name": "Batten's disease protein Cln3 family protein", "refseq_ac": [ { "id": "XP_635365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635365", "type": "external" } ], "gene_names_uniprotkb": "cln3; DDB_G0291157", "gene_names_refseq": "cln3", "protein_names_uniprotkb": "Battenin; Protein CLN3 homolog", "protein_names_refseq": "Batten's disease protein Cln3 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291157)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005765 lysosomal membrane;GO:0030139 endocytic vesicle;GO:0000331 contractile vacuole", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0008285 negative regulation of cell population proliferation;GO:0050714 positive regulation of protein secretion;GO:0098609 cell-cell adhesion;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54F25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54F44-1", "uniprot_id": [ { "id": "NOXC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54F44", "type": "external" } ], "mass": 132499.0, "length": 1142, "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit C", "gene_name": "noxC", "organism": "Cellular slime mold", "refseq_name": "flavocytochrome b large subunit", "refseq_ac": [ { "id": "XP_635387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635387", "type": "external" } ], "gene_names_uniprotkb": "noxC; DDB_G0291117", "gene_names_refseq": "noxC", "protein_names_uniprotkb": "Superoxide-generating NADPH oxidase heavy chain subunit C; 1.-.-.-; NADPH oxidase C; Superoxide-generating NADPH oxidase flavocytochrome C", "protein_names_refseq": "flavocytochrome b large subunit; superoxide-generating NADPH oxidase flavocytochrome", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291117); (R-DDI-3299685); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;15950752", "class_list": "", "function": "Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86MX0", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0005509 calcium ion binding;GO:0020037 heme binding;GO:0016175 superoxide-generating NAD(P)H oxidase activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0006952 defense response;GO:0042742 defense response to bacterium;GO:0042554 superoxide anion generation;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54F44-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54F46-1", "uniprot_id": [ { "id": "WARA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54F46", "type": "external" } ], "mass": 88800.0, "length": 803, "protein_name": "Homeobox protein Wariai", "gene_name": "warA", "organism": "Cellular slime mold", "refseq_name": "homeodomain containing protein", "refseq_ac": [ { "id": "XP_635408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635408", "type": "external" } ], "gene_names_uniprotkb": "warA; DDB_G0291075; hbx1; wri", "gene_names_refseq": "warA", "protein_names_uniprotkb": "Homeobox protein Wariai; DdHbx-1; Homeobox protein 1", "protein_names_refseq": "homeodomain containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291075)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;9486804", "class_list": "", "function": "Putative transcription factor, that seems to be involved in anterior-posterior patterning of the slug, probably by controlling the proportions of prestalk and prespore cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O43988", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0009653 anatomical structure morphogenesis;GO:0031286 negative regulation of sorocarp stalk cell differentiation;GO:1902351 response to imidacloprid", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54F46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54FB9-1", "uniprot_id": [ { "id": "Y0971_DICDI", "url": "https://www.uniprot.org/uniprot/Q54FB9", "type": "external" } ], "mass": 51600.0, "length": 445, "protein_name": "TNF receptor-associated factor family protein DDB_G0290971", "gene_name": "DDB_G0290971", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635418", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0290971", "gene_names_refseq": "", "protein_names_uniprotkb": "TNF receptor-associated factor family protein DDB_G0290971", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290971); (R-DDI-450302); (R-DDI-450321); (R-DDI-5689880); (R-DDI-9020702); (R-DDI-937042); (R-DDI-937072); (R-DDI-975163)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0036019 endolysosome;GO:0140220 pathogen-containing vacuole", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0050830 defense response to Gram-positive bacterium;GO:0036010 protein localization to endosome;GO:0010468 regulation of gene expression;GO:0097212 lysosomal membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54FB9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54FI3-1", "uniprot_id": [ { "id": "STLB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54FI3", "type": "external" } ], "mass": 329909.0, "length": 2968, "protein_name": "Polyketide synthase 37", "gene_name": "StlB", "organism": "Cellular slime mold", "refseq_name": "beta-ketoacyl synthase family protein", "refseq_ac": [ { "id": "XP_635518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635518", "type": "external" } ], "gene_names_uniprotkb": "StlB; DDB_G0290853; pks37", "gene_names_refseq": "stlB", "protein_names_uniprotkb": "Polyketide synthase 37; Steely2; dipks37", "protein_names_refseq": "beta-ketoacyl synthase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290853)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15875012;16906151;17660200;20231486;9446571", "class_list": "", "function": "Polyketide synthase; part of the gene cluster that mediates the biosynthesis of DIF-1 (Differentiation Inducing Factor-1), a signal molecule involved in the differentiation of pstO (prestalk-O) cells (PubMed:16906151). The three-step process begins with the formation of (2,4,6-trihydroxyphenyl)-1-hexan-1-one (THPH) by the polyketide synthase StlB (PubMed:16906151). THPH is then dichlorinated by the flavin-dependent halogenase ChlA (PubMed:20231486). The last step of DIF-1 biosynthesis is the O-methylation of dichloro-THPH (or des-methyl-DIF-1) by the methyltransferase DmtA to yield DIF-1 (PubMed:9446571)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.74", "type": "external" } ], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0031177 phosphopantetheine binding;GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0016210 naringenin-chalcone synthase activity;GO:0106265 THPH synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0006633 fatty acid biosynthetic process;GO:0048102 autophagic cell death;GO:0009813 flavonoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54FI3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54FX2-1", "uniprot_id": [ { "id": "RBLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54FX2", "type": "external" } ], "mass": 149427.0, "length": 1312, "protein_name": "Retinoblastoma-like protein A", "gene_name": "rblA", "organism": "Cellular slime mold", "refseq_name": "Rb-like protein", "refseq_ac": [ { "id": "XP_635645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635645", "type": "external" } ], "gene_names_uniprotkb": "rblA; DDB0188949; Rb", "gene_names_refseq": "rblA", "protein_names_uniprotkb": "Retinoblastoma-like protein A", "protein_names_refseq": "Rb-like protein; Retinoblastoma-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290551); (R-DDI-113501); (R-DDI-1538133); (R-DDI-174178); (R-DDI-2299718); (R-DDI-69200); (R-DDI-69202); (R-DDI-69231); (R-DDI-69656)", "pathway_count": 9, "publication_count": 5, "publication_id_list": "15875012;16495312;20300194;22768168;24390142", "class_list": "", "function": "Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters (By similarity). Plays a dual role, regulating cell-cycle progression and transcriptional events leading to terminal differentiation. In the absence of a G1 phase, functions in late G2 controlling the expression of both S-phase and mitotic genes. Controls stalk/spore preference by suppressing the DIF response in cells destined for the spore pathway. DIF is a chlorinated hydroxyphenone made by cells of spore pathway that promotes stalk differentiation., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q53U28", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0010389 regulation of G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54FX2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54G18-1", "uniprot_id": [ { "id": "GACW_DICDI", "url": "https://www.uniprot.org/uniprot/Q54G18", "type": "external" } ], "mass": 121786.0, "length": 1115, "protein_name": "Rho GTPase-activating protein gacW", "gene_name": "gacW", "organism": "Cellular slime mold", "refseq_name": "RhoGAP domain-containing protein", "refseq_ac": [ { "id": "XP_635754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635754", "type": "external" } ], "gene_names_uniprotkb": "gacW; DDB_G0290439", "gene_names_refseq": "gacW", "protein_names_uniprotkb": "Rho GTPase-activating protein gacW; GTPase activating factor for raC protein W", "protein_names_refseq": "RhoGAP domain-containing protein; leucine-rich repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290439)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Rho GTPase-activating protein involved in the signal transduction pathway., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0031252 cell leading edge", "go_biological_process": "GO:0007165 signal transduction;GO:0016477 cell migration;GO:0032956 regulation of actin cytoskeleton organization;GO:0030334 regulation of cell migration;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54G18-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GC1-1", "uniprot_id": [ { "id": "DGAT2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GC1", "type": "external" } ], "mass": 37330.0, "length": 330, "protein_name": "Diacylglycerol O-acyltransferase 2", "gene_name": "dgat2", "organism": "Cellular slime mold", "refseq_name": "diacylglycerol O-acyltransferase 2", "refseq_ac": [ { "id": "XP_635762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635762", "type": "external" } ], "gene_names_uniprotkb": "dgat2; DDB_G0290279", "gene_names_refseq": "dgat2", "protein_names_uniprotkb": "Diacylglycerol O-acyltransferase 2; 2.3.1.20; 2.3.1.76; ARAT; Acyl-CoA retinol O-fatty-acyltransferase; Diglyceride acyltransferase 2; Retinol O-fatty-acyltransferase", "protein_names_refseq": "diacylglycerol O-acyltransferase 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290279); (R-DDI-1482883); (R-DDI-2142753); (R-DDI-2187335); (R-DDI-75109); (R-DDI-9640463)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" } ], "go_molecular_function": "GO:0004144 diacylglycerol O-acyltransferase activity;GO:0050252 retinol O-fatty-acyltransferase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane;GO:1990578 perinuclear endoplasmic reticulum membrane", "go_biological_process": "GO:0006651 diacylglycerol biosynthetic process;GO:0019432 triglyceride biosynthetic process;GO:0006071 glycerol metabolic process;GO:0006640 monoacylglycerol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54GC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GD0-1", "uniprot_id": [ { "id": "MGP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GD0", "type": "external" } ], "mass": 102301.0, "length": 920, "protein_name": "GTPase activating protein homolog 1", "gene_name": "mgp1", "organism": "Cellular slime mold", "refseq_name": "Cdc15/Fes/CIP4 domain-containing protein", "refseq_ac": [ { "id": "XP_635848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635848", "type": "external" } ], "gene_names_uniprotkb": "mgp1; DDB_G0290233; gacBB", "gene_names_refseq": "mgp1", "protein_names_uniprotkb": "GTPase activating protein homolog 1; GTPase activating factor for raC protein BB; Rho GTPase-activating protein gacBB", "protein_names_refseq": "Cdc15/Fes/CIP4 domain-containing protein; PCH family protein; RhoGAP domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290233); (R-DDI-8856828)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;18334553", "class_list": "", "function": "Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031982 vesicle;GO:0000331 contractile vacuole", "go_biological_process": "GO:0007165 signal transduction;GO:0030041 actin filament polymerization;GO:0016050 vesicle organization;GO:0006887 exocytosis;GO:0051490 negative regulation of filopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54GD0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GH3-1", "uniprot_id": [ { "id": "TOM1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GH3", "type": "external" } ], "mass": 75375.0, "length": 663, "protein_name": "Target of Myb protein 1", "gene_name": "tom1", "organism": "Cellular slime mold", "refseq_name": "GAT domain-containing protein", "refseq_ac": [ { "id": "XP_635855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635855", "type": "external" } ], "gene_names_uniprotkb": "tom1; DDB_G0290163", "gene_names_refseq": "tom1", "protein_names_uniprotkb": "Target of Myb protein 1; DdTom1", "protein_names_refseq": "GAT domain-containing protein; VHS domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290163)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;19054384", "class_list": "", "function": "May contribute to the sorting of ubiquitinated proteins and transfer them for further sorting/trafficking processes to the endosomal multivesicular bodies (MVBs) pathway. Binds to phospholipids, such as phosphatidylinositol PtdIns(3)P and PtdIns(3,5)P2. These phospholipids are involved in the recruitment of the ESCRT machinery to endosomal membranes (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54GH3-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GJ2-1", "uniprot_id": [ { "id": "PUR2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GJ2", "type": "external" } ], "mass": 87706.0, "length": 815, "protein_name": "Bifunctional purine biosynthetic protein purD", "gene_name": "purD", "organism": "Cellular slime mold", "refseq_name": "phosphoribosylamine-glycine ligase", "refseq_ac": [ { "id": "XP_635881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635881", "type": "external" } ], "gene_names_uniprotkb": "purD; DDB_G0290121", "gene_names_refseq": "purD", "protein_names_uniprotkb": "Bifunctional purine biosynthetic protein purD; AIR synthase; AIR synthetase; AIRS; GAR synthetase; GARS; Glycinamide ribonucleotide synthetase; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylglycinamide synthetase", "protein_names_refseq": "phosphoribosylamine-glycine ligase; phosphoribosylformylglycinamide cyclo-ligase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290121); (R-DDI-73817)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.3.1", "type": "external" }, { "id": "6.3.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.13", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004637 phosphoribosylamine-glycine ligase activity;GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006164 purine nucleotide biosynthetic process;GO:0006189 'de novo' IMP biosynthetic process;GO:0046084 adenine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54GJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GN2-1", "uniprot_id": [ { "id": "KTHY_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GN2", "type": "external" } ], "mass": 25582.0, "length": 222, "protein_name": "Thymidylate kinase", "gene_name": "dtymk", "organism": "Cellular slime mold", "refseq_name": "dTMP kinase", "refseq_ac": [ { "id": "XP_635930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635930", "type": "external" } ], "gene_names_uniprotkb": "dtymk; DDB_G0290033; tmkA", "gene_names_refseq": "dtymk", "protein_names_uniprotkb": "Thymidylate kinase; 2.7.4.9; dTMP kinase", "protein_names_refseq": "dTMP kinase; thymidylate kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290033)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP), the immediate precursor for the DNA building block dTTP, with ATP as the preferred phosphoryl donor in the presence of Mg(2+)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.4.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.9", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004798 dTMP kinase activity;GO:0004550 nucleoside diphosphate kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006233 dTDP biosynthetic process;GO:0006227 dUDP biosynthetic process;GO:0006235 dTTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54GN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GP3-1", "uniprot_id": [ { "id": "SPRE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GP3", "type": "external" } ], "mass": 30187.0, "length": 267, "protein_name": "Sepiapterin reductase", "gene_name": "sprA", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "sprA; DDB_G0290009", "gene_names_refseq": "", "protein_names_uniprotkb": "Sepiapterin reductase; 1.1.1.153; SPR; SR", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290009); (R-DDI-1474151); (R-DDI-203615)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10987137;15875012;15896778;16527408;17976377", "class_list": "", "function": "Catalyzes the production of D-threo-tetrahydrobiopterin (tetrahydrodictyopterin or DH4), also known as dictyopterin, and in a much smaller amount that of its stereoisomer L-erythro-tetrahydrobiopterin ((6R)-L-erythro-5,6,7,8-tetrahydrobiopterin or BH4) (PubMed:16527408). Prefers 1-oxo-2-D-hydroxypropyl-tetrahydropterin to 6-pyruvoyltetrahydropterin (6-pyruvoyl-5,6,7,8-tetrahydropterin) as a substrate, thereby maintaining dominant production of DH4 over BH4 in sufficient supply of an aldose reductase-like enzyme (PubMed:16527408). DH4 represents more than 95% of the total tetrahydrobiopterin production. It has a direct antioxidant function to protect mitochondria against oxidative stress (PubMed:17976377). Essential for the last step of BH4 synthesis (PubMed:10987137, PubMed:15896778). Also catalyzes the conversion of sepiapterin to L-erythro-7,8-dihydrobiopterin, which is then reduced to BH4 by dihydrofolate reductase, constituting the salvage pathway of BH4 (PubMed:10987137)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9NGC5", "ec_number_list": [ { "id": "1.1.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.153", "type": "external" } ], "go_molecular_function": "GO:0004757 sepiapterin reductase (NADP+) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0006729 tetrahydrobiopterin biosynthetic process;GO:0042559 pteridine-containing compound biosynthetic process;GO:0140460 response to Gram-negative bacterium", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54GP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GP8-1", "uniprot_id": [ { "id": "GLRX_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GP8", "type": "external" } ], "mass": 10934.0, "length": 100, "protein_name": "Glutaredoxin", "gene_name": "grxA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635914", "type": "external" } ], "gene_names_uniprotkb": "grxA; DDB_G0290015; grx1", "gene_names_refseq": "grxA", "protein_names_uniprotkb": "Glutaredoxin", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290015)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16678813", "class_list": "", "function": "Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Affects the culmination and cell fate decision by modulating the levels of reduced glutathione., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0015038 glutathione disulfide oxidoreductase activity;GO:0043295 glutathione binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0034599 cellular response to oxidative stress;GO:0045454 cell redox homeostasis;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54GP8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GQ6-1", "uniprot_id": [ { "id": "ACOX1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GQ6", "type": "external" } ], "mass": 79762.0, "length": 700, "protein_name": "Peroxisomal acyl-coenzyme A oxidase 1", "gene_name": "acox1", "organism": "Cellular slime mold", "refseq_name": "acyl-CoA oxidase", "refseq_ac": [ { "id": "XP_635946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635946", "type": "external" } ], "gene_names_uniprotkb": "acox1; DDB_G0289993", "gene_names_refseq": "", "protein_names_uniprotkb": "Peroxisomal acyl-coenzyme A oxidase 1; 1.3.3.6", "protein_names_refseq": "acyl-CoA oxidase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289993); (R-DDI-193368); (R-DDI-2046106); (R-DDI-389887); (R-DDI-390247); (R-DDI-9033241)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "4.2.1.119", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.119", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "1.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.4", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" } ], "go_molecular_function": "GO:0005504 fatty acid binding;GO:0042803 protein homodimerization activity;GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0003997 acyl-CoA oxidase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006091 generation of precursor metabolites and energy;GO:0006629 lipid metabolic process;GO:0009062 fatty acid catabolic process;GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase;GO:0019395 fatty acid oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54GQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GT9-1", "uniprot_id": [ { "id": "ATG5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GT9", "type": "external" } ], "mass": 46061.0, "length": 398, "protein_name": "Autophagy protein 5", "gene_name": "atg5", "organism": "Cellular slime mold", "refseq_name": "autophagy protein 5", "refseq_ac": [ { "id": "XP_635980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635980", "type": "external" } ], "gene_names_uniprotkb": "atg5; DDB_G0289881; apg5", "gene_names_refseq": "atg5", "protein_names_uniprotkb": "Autophagy protein 5", "protein_names_refseq": "autophagy protein 5", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289881); (R-DDI-1632852)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12626495;15875012", "class_list": "", "function": "Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86CS1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane;GO:0034274 Atg12-Atg5-Atg16 complex;GO:0061908 phagophore", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0006909 phagocytosis;GO:0016236 macroautophagy;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54GT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GV7-1", "uniprot_id": [ { "id": "SIR2D_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GV7", "type": "external" } ], "mass": 62142.0, "length": 542, "protein_name": "NAD-dependent deacetylase sir2D", "gene_name": "sir2D", "organism": "Cellular slime mold", "refseq_name": "NAD(+)-dependent deacetylase, silent information regulator protein family protein", "refseq_ac": [ { "id": "XP_635962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635962", "type": "external" } ], "gene_names_uniprotkb": "sir2D; DDB_G0289967", "gene_names_refseq": "sir2D", "protein_names_uniprotkb": "NAD-dependent deacetylase sir2D; 2.3.1.286; Silent information regulator sir2D", "protein_names_refseq": "NAD(+)-dependent deacetylase, silent information regulator protein family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289967); (R-DDI-9856649)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "NAD-dependent deacetylase, which plays an important role in the regulation of transcriptional repression., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0046970 histone H4K16 deacetylase activity, NAD-dependent;GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0070403 NAD+ binding;GO:0032041 histone H3K14 deacetylase activity, NAD-dependent", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0006974 DNA damage response;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54GV7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GX7-1", "uniprot_id": [ { "id": "ACT10_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GX7", "type": "external" } ], "mass": 41747.0, "length": 376, "protein_name": "Actin-10", "gene_name": "act10", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636030", "type": "external" } ], "gene_names_uniprotkb": "act10; DDB_G0289811", "gene_names_refseq": "act10", "protein_names_uniprotkb": "Actin-10; 3.6.4.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289811); (R-DDI-114608); (R-DDI-2029482); (R-DDI-5626467); (R-DDI-5663213); (R-DDI-9013418); (R-DDI-9953170)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0017022 myosin binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005884 actin filament;GO:0005911 cell-cell junction;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0006897 endocytosis;GO:0006935 chemotaxis;GO:0006909 phagocytosis;GO:0000902 cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54GX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54GY6-1", "uniprot_id": [ { "id": "KXCA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54GY6", "type": "external" } ], "mass": 149141.0, "length": 1311, "protein_name": "Kinase and exchange factor for Rac A", "gene_name": "kxcA", "organism": "Cellular slime mold", "refseq_name": "IQ calmodulin-binding domain-containing protein", "refseq_ac": [ { "id": "XP_636021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636021", "type": "external" } ], "gene_names_uniprotkb": "kxcA; DDB_G0289859; RacGEF", "gene_names_refseq": "kxcA", "protein_names_uniprotkb": "Kinase and exchange factor for Rac A; 2.7.11.1; Serine/threonine-protein kinase kxcA", "protein_names_refseq": "IQ calmodulin-binding domain-containing protein; LISK family protein kinase; RhoGEF domain-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289859)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16762450", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54GY6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54H45-1", "uniprot_id": [ { "id": "DRKB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54H45", "type": "external" } ], "mass": 76041.0, "length": 690, "protein_name": "Probable serine/threonine-protein kinase drkB", "gene_name": "drkB", "organism": "Cellular slime mold", "refseq_name": "DRK subfamily protein kinase", "refseq_ac": [ { "id": "XP_636073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636073", "type": "external" } ], "gene_names_uniprotkb": "drkB; DDB_G0289709; rk2", "gene_names_refseq": "drkB", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase drkB; 2.7.11.1; Receptor-like kinase 2; Receptor-like kinase B; Vesicle-associated receptor tyrosine kinase-like protein 2", "protein_names_refseq": "DRK subfamily protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289709)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 10, "predicted_n_glycosites": 4, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54H45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54H46-1", "uniprot_id": [ { "id": "DRKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54H46", "type": "external" } ], "mass": 72324.0, "length": 642, "protein_name": "Probable serine/threonine-protein kinase drkA", "gene_name": "drkA", "organism": "Cellular slime mold", "refseq_name": "DRK subfamily protein kinase", "refseq_ac": [ { "id": "XP_636072", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636072", "type": "external" } ], "gene_names_uniprotkb": "drkA; DDB_G0289791; rk1; vsk1", "gene_names_refseq": "drkA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase drkA; 2.7.11.1; Receptor-like kinase 1; Receptor-like kinase A; Vesicle-associated receptor tyrosine kinase-like protein 1", "protein_names_refseq": "DRK subfamily protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289791)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 9, "predicted_n_glycosites": 5, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0097677 STAT family protein binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0097696 cell surface receptor signaling pathway via STAT", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54H46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54H80-1", "uniprot_id": [ { "id": "PEMT2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54H80", "type": "external" } ], "mass": 22416.0, "length": 200, "protein_name": "Phosphatidylethanolamine N-methyltransferase B", "gene_name": "pemtB", "organism": "Cellular slime mold", "refseq_name": "phosphatidylethanolamine N-methyltransferase", "refseq_ac": [ { "id": "XP_636144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636144", "type": "external" } ], "gene_names_uniprotkb": "pemtB; DDB_G0289645", "gene_names_refseq": "pemtB", "protein_names_uniprotkb": "Phosphatidylethanolamine N-methyltransferase B; 2.1.1.17; 2.1.1.71; PEAMT; PEMT; PLMT; Phospholipid methyltransferase B", "protein_names_refseq": "phosphatidylethanolamine N-methyltransferase; phospholipid methyltransferase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289645)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.17", "type": "external" }, { "id": "2.1.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.71", "type": "external" } ], "go_molecular_function": "GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity;GO:0004608 phosphatidylethanolamine N-methyltransferase activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006656 phosphatidylcholine biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54H80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HC6-1", "uniprot_id": [ { "id": "ARKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HC6", "type": "external" } ], "mass": 161727.0, "length": 1460, "protein_name": "Ankyrin repeat-containing protein kinase A", "gene_name": "arkA", "organism": "Cellular slime mold", "refseq_name": "ARK family protein kinase", "refseq_ac": [ { "id": "XP_636166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636166", "type": "external" } ], "gene_names_uniprotkb": "arkA; DDB_G0289555; arck-1", "gene_names_refseq": "arkA", "protein_names_uniprotkb": "Ankyrin repeat-containing protein kinase A; 2.7.11.1; Ankyrin repeat-containing protein kinase 1", "protein_names_refseq": "ARK family protein kinase; GRAM domain-containing protein; PKC domain-containing protein, PE/DAG binding; ankyrin repeat-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289555); (R-DDI-168638); (R-DDI-170968); (R-DDI-3295583); (R-DDI-392517); (R-DDI-5213460); (R-DDI-5621575); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5674499); (R-DDI-5675221); (R-DDI-5675482); (R-DDI-5689880)", "pathway_count": 13, "publication_count": 2, "publication_id_list": "14597204;15875012", "class_list": "", "function": "Involved in the development of the fruiting body. Overexpression phenocopies the spnA null phenotype., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0007165 signal transduction;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54HC6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HG2-1", "uniprot_id": [ { "id": "CTXA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HG2", "type": "external" } ], "mass": 50505.0, "length": 444, "protein_name": "Cortexillin-1", "gene_name": "ctxA", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_636175", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636175", "type": "external" } ], "gene_names_uniprotkb": "ctxA; DDB_G0289483", "gene_names_refseq": "ctxA", "protein_names_uniprotkb": "Cortexillin-1; Cortexillin I", "protein_names_refseq": "actin binding protein; actin bundling protein; cortexillin I", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289483)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10745004;15875012;18039932;8752217", "class_list": "", "function": "Actin-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15813", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0019887 protein kinase regulator activity;GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0045180 basal cortex;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0051495 positive regulation of cytoskeleton organization;GO:0010628 positive regulation of gene expression;GO:0000902 cell morphogenesis;GO:0009617 response to bacterium;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54HG2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HH2-1", "uniprot_id": [ { "id": "SRR_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HH2", "type": "external" } ], "mass": 35092.0, "length": 324, "protein_name": "Serine racemase", "gene_name": "srr", "organism": "Cellular slime mold", "refseq_name": "serine racemase", "refseq_ac": [ { "id": "XP_636213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636213", "type": "external" } ], "gene_names_uniprotkb": "srr; DDB_G0289463", "gene_names_refseq": "srr", "protein_names_uniprotkb": "Serine racemase; 4.3.1.17; 4.3.1.18; 5.1.1.18; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase", "protein_names_refseq": "serine racemase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289463); (R-DDI-977347)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "15875012;22311068;32474107", "class_list": "", "function": "Pyridoxal-5'-phosphate (PLP)-dependent enzyme that catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. In addition to racemization, has dehydratase activity towards both L-serine and D-serine, a two-step reaction in which the hydroxyl group of serine is eliminated to produce aminoacrylate (2-aminoprop-2-enoate), and then the aminoacrylate (an unstable intermediate) is deaminated by nonenzymatic hydrolysis to produce pyruvate., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.3.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.1.18", "type": "external" }, { "id": "5.1.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.1.18", "type": "external" }, { "id": "4.3.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.1.17", "type": "external" } ], "go_molecular_function": "GO:0008721 D-serine ammonia-lyase activity;GO:0030378 serine racemase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042866 pyruvate biosynthetic process;GO:0070179 D-serine biosynthetic process;GO:0036088 D-serine catabolic process;GO:0006563 L-serine metabolic process;GO:0006565 L-serine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54HH2-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HI0-1", "uniprot_id": [ { "id": "ANM2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HI0", "type": "external" } ], "mass": 58871.0, "length": 512, "protein_name": "Protein arginine N-methyltransferase 2", "gene_name": "prmt2", "organism": "Cellular slime mold", "refseq_name": "protein arginine methyltransferase", "refseq_ac": [ { "id": "XP_636224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636224", "type": "external" } ], "gene_names_uniprotkb": "prmt2; DDB_G0289445", "gene_names_refseq": "prmt2", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 2; 2.1.1.319; Histone-arginine N-methyltransferase PRMT2", "protein_names_refseq": "protein arginine methyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289445); (R-DDI-3214858)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in some proteins such as histones., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" } ], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0016274 protein-arginine N-methyltransferase activity;GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054 histone methyltransferase activity;GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0060765 regulation of androgen receptor signaling pathway;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54HI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HI5-1", "uniprot_id": [ { "id": "LMNB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HI5", "type": "external" } ], "mass": 81350.0, "length": 716, "protein_name": "Lamin-like protein", "gene_name": "lmnB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636248", "type": "external" } ], "gene_names_uniprotkb": "lmnB; DDB_G0289429", "gene_names_refseq": "", "protein_names_uniprotkb": "Lamin-like protein; Protein NE81", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289429)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;19466752;22090348", "class_list": "", "function": "Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed:22090348). Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics (By similarity). The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively (By similarity). Helps to maintain integrity of nuclear structures in response to mechanical stress (PubMed:22090348)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005637 nuclear inner membrane;GO:0005652 nuclear lamina;GO:0005638 lamin filament", "go_biological_process": "GO:0006325 chromatin organization;GO:0007098 centrosome cycle;GO:0051642 centrosome localization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54HI5-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HS3-1", "uniprot_id": [ { "id": "SET1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HS3", "type": "external" } ], "mass": 170527.0, "length": 1486, "protein_name": "Histone-lysine N-methyltransferase set1", "gene_name": "set1", "organism": "Cellular slime mold", "refseq_name": "SET domain-containing protein", "refseq_ac": [ { "id": "XP_636258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636258", "type": "external" } ], "gene_names_uniprotkb": "set1; DDB_G0289257; H3K4", "gene_names_refseq": "set1", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase set1; 2.1.1.354; Histone H3 lysine 4 methyltransferase; SET domain-containing protein 1", "protein_names_refseq": "SET domain-containing protein; histone H3 lysine 4 methyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289257); (R-DDI-9772755)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;16469305", "class_list": "", "function": "Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3 (PubMed:16469305). Binds RNAs which might negatively affect its histone methyltransferase activity (By similarity). COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face (By similarity). May act to regulate chromatin-mediated events (PubMed:16469305)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0140999 histone H3K4 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0048188 Set1C/COMPASS complex", "go_biological_process": "GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0032259 methylation;GO:0040029 epigenetic regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54HS3-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HS9-1", "uniprot_id": [ { "id": "AP1M_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HS9", "type": "external" } ], "mass": 48565.0, "length": 428, "protein_name": "AP-1 complex subunit mu", "gene_name": "apm1", "organism": "Cellular slime mold", "refseq_name": "clathrin-adaptor medium chain AP-1", "refseq_ac": [ { "id": "XP_636252", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636252", "type": "external" } ], "gene_names_uniprotkb": "apm1; DDB_G0289247", "gene_names_refseq": "apm1", "protein_names_uniprotkb": "AP-1 complex subunit mu; AP-1 adaptor complex mu1 subunit; Adaptor protein complex AP-1 subunit mu; Adaptor-related protein complex 1 subunit mu; Clathrin-adaptor medium chain Apm1; Mu1-adaptin", "protein_names_refseq": "clathrin-adaptor medium chain AP-1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289247); (R-DDI-432720); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "11179674;12802059;14617812;15875012;16782229", "class_list": "", "function": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GPF2", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005802 trans-Golgi network;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007032 endosome organization;GO:0007041 lysosomal transport;GO:0006896 Golgi to vacuole transport;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54HS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HT1-1", "uniprot_id": [ { "id": "TIRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HT1", "type": "external" } ], "mass": 155247.0, "length": 1336, "protein_name": "Protein tirA", "gene_name": "tirA", "organism": "Cellular slime mold", "refseq_name": "Toll-Interleukin receptor domain-containing protein", "refseq_ac": [ { "id": "XP_636358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636358", "type": "external" } ], "gene_names_uniprotkb": "tirA; DDB_G0289237", "gene_names_refseq": "tirA", "protein_names_uniprotkb": "Protein tirA; 3.2.2.6; TIR domain-containing protein A", "protein_names_refseq": "Toll-Interleukin receptor domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289237); (R-DDI-1169408); (R-DDI-936440); (R-DDI-983168); (R-DDI-9833482); (R-DDI-9909505)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "15875012;17673666;18590548", "class_list": "", "function": "May regulate responses to pathogens. Required by to respond appropriately to bacteria during vegetative foraging., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006952 defense response;GO:0007165 signal transduction;GO:0032496 response to lipopolysaccharide;GO:0006909 phagocytosis;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54HT1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54HY0-1", "uniprot_id": [ { "id": "PDE7_DICDI", "url": "https://www.uniprot.org/uniprot/Q54HY0", "type": "external" } ], "mass": 48505.0, "length": 425, "protein_name": "cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase 7", "gene_name": "pde7", "organism": "Cellular slime mold", "refseq_name": "cAMP phosphodiesterase", "refseq_ac": [ { "id": "XP_636383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636383", "type": "external" } ], "gene_names_uniprotkb": "pde7; DDB_G0289145", "gene_names_refseq": "pde7", "protein_names_uniprotkb": "cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase 7; 3.1.4.35; 3.1.4.53; Phosphodiesterase 7; ddPDE7", "protein_names_refseq": "cAMP phosphodiesterase; cGMP phosphodiesterase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289145)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;17040207;18559084", "class_list": "", "function": "Phosphodiesterase with dual cAMP/cGMP specificity. However, displays a preference for cAMP over cGMP. Seems to regulate cAMP/cGMP concentration especially during cell aggregation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" } ], "go_molecular_function": "GO:0030552 cAMP binding;GO:0030553 cGMP binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0006198 cAMP catabolic process;GO:1902660 negative regulation of glucose mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54HY0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54I18-1", "uniprot_id": [ { "id": "SMEK_DICDI", "url": "https://www.uniprot.org/uniprot/Q54I18", "type": "external" } ], "mass": 119988.0, "length": 1046, "protein_name": "Suppressor of Mek1", "gene_name": "smkA", "organism": "Cellular slime mold", "refseq_name": "EVH1 domain-containing protein", "refseq_ac": [ { "id": "XP_636416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636416", "type": "external" } ], "gene_names_uniprotkb": "smkA; DDB_G0289067", "gene_names_refseq": "smkA", "protein_names_uniprotkb": "Suppressor of Mek1; SMEK", "protein_names_refseq": "EVH1 domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289067)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;16107728;17353263", "class_list": "", "function": "Suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects. Required for proper cytokinesis during vegetative growth, timely exit from the mound stage during development, and myosin II assembly. May be a regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) and may control localization of PP4 to the nucleus. Involved in the regulation of some ppp4c functions, such as developmental progression, chemotaxis, expression of stress response genes and cell movement., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005938 cell cortex;GO:0030289 protein phosphatase 4 complex", "go_biological_process": "GO:0007165 signal transduction;GO:0006974 DNA damage response;GO:2000779 regulation of double-strand break repair;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54I18-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54I36-1", "uniprot_id": [ { "id": "PYK3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54I36", "type": "external" } ], "mass": 149944.0, "length": 1338, "protein_name": "Dual specificity protein kinase pyk3", "gene_name": "pyk3", "organism": "Cellular slime mold", "refseq_name": "DPYK family protein kinase", "refseq_ac": [ { "id": "XP_636435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636435", "type": "external" } ], "gene_names_uniprotkb": "pyk3; DDB_G0289001; DpyK3; pkyA", "gene_names_refseq": "pyk3", "protein_names_uniprotkb": "Dual specificity protein kinase pyk3; 2.7.12.1; Tyrosine-protein kinase 3", "protein_names_refseq": "DPYK family protein kinase; protein kinase, TKL group; protein tyrosine kinase; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289001)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;18657170;8898113", "class_list": "", "function": "Involved in the development. Negatively regulates tyrosine phosphorylation and activation state of dstC/STATc, probably by activating a dstC/STATc phosphatase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q23846;Q23927", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0007165 signal transduction;GO:0010628 positive regulation of gene expression;GO:0045595 regulation of cell differentiation;GO:0006972 hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54I36-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54I64-1", "uniprot_id": [ { "id": "Q54I64_DICDI", "url": "https://www.uniprot.org/uniprot/Q54I64", "type": "external" } ], "mass": 91846.0, "length": 817, "protein_name": "RasGTPase-activating protein", "gene_name": "DDB_G0288977", "organism": "Cellular slime mold", "refseq_name": "IQGAP-related protein", "refseq_ac": [ { "id": "XP_636446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636446", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0288977", "gene_names_refseq": "", "protein_names_uniprotkb": "RasGTPase-activating protein", "protein_names_refseq": "IQGAP-related protein; RasGTPase-activating protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288977)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0031267 small GTPase binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0005938 cell cortex;GO:0044354 macropinosome", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0010811 positive regulation of cell-substrate adhesion;GO:0050765 negative regulation of phagocytosis;GO:0048870 cell motility;GO:1905302 negative regulation of macropinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54I64-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54I71-1", "uniprot_id": [ { "id": "AARA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54I71", "type": "external" } ], "mass": 85924.0, "length": 757, "protein_name": "Protein aardvark", "gene_name": "aarA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636508", "type": "external" } ], "gene_names_uniprotkb": "aarA; DDB_G0288877; aar; sab6", "gene_names_refseq": "aarA", "protein_names_uniprotkb": "Protein aardvark; Suppressor of amiB protein 16", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288877)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11130075;11792801;12128211;15875012;18164290", "class_list": "", "function": "Required to regulate pattern formation during multi-cellular stages of development and for the formation of adherens junctions. Plays a structural role during the regulation of stalk formation. Involved in cell signaling. Required for spore-cell differentiation. Overexpression increases number and size of cell junctions and reduces spore-cell formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GSG6", "ec_number_list": [], "go_molecular_function": "GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0045180 basal cortex;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005911 cell-cell junction;GO:0005912 adherens junction", "go_biological_process": "GO:0051495 positive regulation of cytoskeleton organization;GO:0007155 cell adhesion;GO:0031032 actomyosin structure organization;GO:0008104 intracellular protein localization;GO:0009306 protein secretion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54I71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54I89-1", "uniprot_id": [ { "id": "RENT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54I89", "type": "external" } ], "mass": 151558.0, "length": 1331, "protein_name": "Regulator of nonsense transcripts 1", "gene_name": "upf1", "organism": "Cellular slime mold", "refseq_name": "regulator of nonsense transcripts 1", "refseq_ac": [ { "id": "XP_636490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636490", "type": "external" } ], "gene_names_uniprotkb": "upf1; DDB_G0288923", "gene_names_refseq": "upf1", "protein_names_uniprotkb": "Regulator of nonsense transcripts 1; 5.6.2.3; 5.6.2.5; Double-stranded nucleic acid 5'-3' helicase Upf1; Up-frameshift suppressor 1 homolog", "protein_names_refseq": "regulator of nonsense transcripts 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288923); (R-DDI-975956); (R-DDI-975957)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. The formation of a surveillance complex is believed to activate NMD., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0043024 ribosomal small subunit binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54I89-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54I90-1", "uniprot_id": [ { "id": "NDUV1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54I90", "type": "external" } ], "mass": 52691.0, "length": 479, "protein_name": "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial", "gene_name": "ndufv1", "organism": "Cellular slime mold", "refseq_name": "NADH dehydrogenase ubiquinone flavoprotein 1", "refseq_ac": [ { "id": "XP_636489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636489", "type": "external" } ], "gene_names_uniprotkb": "ndufv1; DDB_G0288875; qinA; rcdG; veg107", "gene_names_refseq": "ndufv1", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; 7.1.1.2; CI-51kD; Complex I-51kD; NADH-ubiquinone oxidoreductase 51 kDa subunit", "protein_names_refseq": "NADH dehydrogenase ubiquinone flavoprotein 1; NADH-ubiquinone oxidoreductase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288875); (R-DDI-6799198); (R-DDI-9837999)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;8643615", "class_list": "", "function": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q23923", "ec_number_list": [ { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051287 NAD binding;GO:0016491 oxidoreductase activity;GO:0008137 NADH dehydrogenase (ubiquinone) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0006120 mitochondrial electron transport, NADH to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54I90-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54IE8-1", "uniprot_id": [ { "id": "IRLE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54IE8", "type": "external" } ], "mass": 156241.0, "length": 1350, "protein_name": "Probable serine/threonine-protein kinase irlE", "gene_name": "irlE", "organism": "Cellular slime mold", "refseq_name": "IRE family protein kinase", "refseq_ac": [ { "id": "XP_636529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636529", "type": "external" } ], "gene_names_uniprotkb": "irlE; DDB_G0288803", "gene_names_refseq": "irlE", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase irlE; 2.7.11.1; Inositol-requiring protein-like protein kinase E", "protein_names_refseq": "IRE family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288803); (R-DDI-381070)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0004521 RNA endonuclease activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006397 mRNA processing;GO:0036498 IRE1-mediated unfolded protein response;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54IE8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54IF7-1", "uniprot_id": [ { "id": "VPS29_DICDI", "url": "https://www.uniprot.org/uniprot/Q54IF7", "type": "external" } ], "mass": 20414.0, "length": 183, "protein_name": "Vacuolar protein sorting-associated protein 29", "gene_name": "vps29", "organism": "Cellular slime mold", "refseq_name": "metallophosphoesterase domain-containing protein", "refseq_ac": [ { "id": "XP_636520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636520", "type": "external" } ], "gene_names_uniprotkb": "vps29; DDB_G0288787", "gene_names_refseq": "vps29", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 29; 3.1.3.3", "protein_names_refseq": "metallophosphoesterase domain-containing protein; vacuolar sorting protein 29", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288787); (R-DDI-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.3", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0036424 L-phosphoserine phosphatase activity", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0032010 phagolysosome;GO:0010008 endosome membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54IF7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54IL5-1", "uniprot_id": [ { "id": "UGT52_DICDI", "url": "https://www.uniprot.org/uniprot/Q54IL5", "type": "external" } ], "mass": 190915.0, "length": 1697, "protein_name": "UDP-sugar-dependent glycosyltransferase 52", "gene_name": "ugt52", "organism": "Cellular slime mold", "refseq_name": "FYVE-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_636616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636616", "type": "external" } ], "gene_names_uniprotkb": "ugt52; DDB_G0288655", "gene_names_refseq": "ugt52", "protein_names_uniprotkb": "UDP-sugar-dependent glycosyltransferase 52; 2.4.1.173; Sterol 3-beta-glucosyltransferase; UDP-glycosyltransferase 52", "protein_names_refseq": "FYVE-type zinc finger-containing protein; GRAM domain-containing protein; sterol glucosyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288655)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10224056;15875012", "class_list": "glycogene;glycosyltransferase", "function": "Involved in the biosynthesis of sterol glucoside. Can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9XYD4", "ec_number_list": [ { "id": "2.4.1.173", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.173", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016906 sterol 3-beta-glucosyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0016126 sterol biosynthetic process;GO:0016125 sterol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54IL5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54IR8-1", "uniprot_id": [ { "id": "WASC5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54IR8", "type": "external" } ], "mass": 134897.0, "length": 1164, "protein_name": "WASH complex subunit 5", "gene_name": "washc5", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636646", "type": "external" } ], "gene_names_uniprotkb": "washc5; DDB_G0288569", "gene_names_refseq": "", "protein_names_uniprotkb": "WASH complex subunit 5; WASH complex subunit strumpellin homolog", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288569)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0071203 WASH complex;GO:0061474 phagolysosome membrane", "go_biological_process": "GO:0051125 regulation of actin nucleation;GO:0006909 phagocytosis;GO:0007032 endosome organization;GO:0007040 lysosome organization;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54IR8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54IZ9-1", "uniprot_id": [ { "id": "RPC2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54IZ9", "type": "external" } ], "mass": 183030.0, "length": 1608, "protein_name": "DNA-directed RNA polymerase III subunit rpc2", "gene_name": "polr3b", "organism": "Cellular slime mold", "refseq_name": "RNA polymerase III, second largest subunit", "refseq_ac": [ { "id": "XP_636731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636731", "type": "external" } ], "gene_names_uniprotkb": "polr3b; DDB_G0288449; rpc2", "gene_names_refseq": "rpc2", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit rpc2; 2.7.7.6; DNA-directed RNA polymerase III subunit B; RNA polymerase III subunit C2", "protein_names_refseq": "RNA polymerase III, second largest subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288449); (R-DDI-76061); (R-DDI-76066)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;17069655", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and rpc2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.7.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.48", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0032549 ribonucleoside binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005736 RNA polymerase I complex;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0006360 transcription by RNA polymerase I;GO:0006354 DNA-templated transcription elongation;GO:0042796 snRNA transcription by RNA polymerase III;GO:0016539 intein-mediated protein splicing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54IZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54J08-1", "uniprot_id": [ { "id": "ACAC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54J08", "type": "external" } ], "mass": 256735.0, "length": 2282, "protein_name": "Acetyl-CoA carboxylase", "gene_name": "accA", "organism": "Cellular slime mold", "refseq_name": "acetyl-CoA carboxylase", "refseq_ac": [ { "id": "XP_636722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636722", "type": "external" } ], "gene_names_uniprotkb": "accA; DDB_G0288387", "gene_names_refseq": "accA", "protein_names_uniprotkb": "Acetyl-CoA carboxylase; 6.4.1.2; ACC-alpha", "protein_names_refseq": "acetyl-CoA carboxylase; biotin carboxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288387); (R-DDI-196780); (R-DDI-200425); (R-DDI-75105)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.14", "type": "external" }, { "id": "6.4.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0046872 metal ion binding;GO:0003989 acetyl-CoA carboxylase activity;GO:0004075 biotin carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:2001295 malonyl-CoA biosynthetic process;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54J08-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54J33-1", "uniprot_id": [ { "id": "P2XD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54J33", "type": "external" } ], "mass": 46362.0, "length": 407, "protein_name": "P2X receptor D", "gene_name": "p2xD", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636768", "type": "external" } ], "gene_names_uniprotkb": "p2xD; DDB_G0288335", "gene_names_refseq": "p2xD", "protein_names_uniprotkb": "P2X receptor D; P2XD", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288335); (R-DDI-139853); (R-DDI-418346); (R-DDI-6798695); (R-DDI-844456)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15875012;19833731", "class_list": "", "function": "P2X receptors are ligand-gated ion channels that play a role in intracellular calcium signaling. ATP does not evoke inward currents in p2xD. Not essential for osmoregulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035381 ATP-gated ion channel activity;GO:0140417 intracellularly ATP-gated calcium channel activity", "go_cellular_component": "GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0070588 calcium ion transmembrane transport;GO:0050848 regulation of calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54J33-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54J97-1", "uniprot_id": [ { "id": "CH60_DICDI", "url": "https://www.uniprot.org/uniprot/Q54J97", "type": "external" } ], "mass": 59846.0, "length": 556, "protein_name": "60 kDa heat shock protein, mitochondrial", "gene_name": "hspA", "organism": "Cellular slime mold", "refseq_name": "chaperonin 60", "refseq_ac": [ { "id": "XP_636839", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636839", "type": "external" } ], "gene_names_uniprotkb": "hspA; DDB_G0288181", "gene_names_refseq": "hspA", "protein_names_uniprotkb": "60 kDa heat shock protein, mitochondrial; 60 kDa chaperonin; CPN60; Chaperonin 60; HSP-60; Heat shock protein 60; Hsp60", "protein_names_refseq": "chaperonin 60; heat shock 60", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288181); (R-DDI-9837999)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12952082;15875012", "class_list": "", "function": "Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95025", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051087 protein-folding chaperone binding;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006457 protein folding;GO:0042742 defense response to bacterium;GO:0007005 mitochondrion organization;GO:0009408 response to heat;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54J97-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JC7-1", "uniprot_id": [ { "id": "Y1197_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JC7", "type": "external" } ], "mass": 152496.0, "length": 1347, "protein_name": "Probable serine/threonine-protein kinase DDB_G0288147", "gene_name": "DDB_G0288147", "organism": "Cellular slime mold", "refseq_name": "PKC domain-containing protein, PE/DAG binding", "refseq_ac": [ { "id": "XP_636866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636866", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0288147", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0288147; 2.7.11.1", "protein_names_refseq": "PKC domain-containing protein, PE/DAG binding; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288147); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005764 lysosome", "go_biological_process": "GO:0051984 positive regulation of chromosome segregation;GO:0007165 signal transduction;GO:0010628 positive regulation of gene expression;GO:0022407 regulation of cell-cell adhesion;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54JC7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JG7-1", "uniprot_id": [ { "id": "DST4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JG7", "type": "external" } ], "mass": 53775.0, "length": 485, "protein_name": "Serine/threonine-protein kinase dst4", "gene_name": "dst4", "organism": "Cellular slime mold", "refseq_name": "STE20 family protein kinase", "refseq_ac": [ { "id": "XP_636883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636883", "type": "external" } ], "gene_names_uniprotkb": "dst4; DDB_G0288071; dstD", "gene_names_refseq": "dst4", "protein_names_uniprotkb": "Serine/threonine-protein kinase dst4; 2.7.11.1", "protein_names_refseq": "STE20 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288071)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16842885", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007165 signal transduction;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54JG7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JH4-1", "uniprot_id": [ { "id": "P2XE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JH4", "type": "external" } ], "mass": 43829.0, "length": 388, "protein_name": "P2X receptor E", "gene_name": "p2xE", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636957", "type": "external" } ], "gene_names_uniprotkb": "p2xE; DDB_G0288061", "gene_names_refseq": "p2xE", "protein_names_uniprotkb": "P2X receptor E; P2XE", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288061); (R-DDI-139853); (R-DDI-418346); (R-DDI-6798695); (R-DDI-844456)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "15875012;18486207;19833731", "class_list": "", "function": "P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Not essential for osmoregulation. Inward currents evoked by intracellular ATP. ATP analog beta, gamma-imido-ATP is a weak partial agonist of p2xE. Exclusively selective for ATP over other nucleotides. Insensitive to copper and P2 receptor antagonists PPADS and suramin but strongly inhibited by sodium ions. More permeable to ammonium than either sodium or potassium ions and less permeable to choline. Permeable to calcium ions, but not chloride., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0035381 ATP-gated ion channel activity;GO:0140417 intracellularly ATP-gated calcium channel activity", "go_cellular_component": "GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0006811 monoatomic ion transport;GO:0070588 calcium ion transmembrane transport;GO:0050848 regulation of calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54JH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JH6-1", "uniprot_id": [ { "id": "CMT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JH6", "type": "external" } ], "mass": 44115.0, "length": 379, "protein_name": "DNA (cytosine-5)-methyltransferase", "gene_name": "dnmA", "organism": "Cellular slime mold", "refseq_name": "DNA -methyltransferase", "refseq_ac": [ { "id": "XP_636955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636955", "type": "external" } ], "gene_names_uniprotkb": "dnmA; DDB_G0288047", "gene_names_refseq": "dnmA", "protein_names_uniprotkb": "DNA (cytosine-5)-methyltransferase; 2.1.1.37", "protein_names_refseq": "DNA -methyltransferase; DNA methyltransferase 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288047)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15689527;15875012;16282589;16400165", "class_list": "", "function": "Involved in epigenetic gene silencing. Methylates specific cytosine residues in the retrotransposons DIRS-1 and Skipper., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.37", "type": "external" } ], "go_molecular_function": "GO:0003886 DNA (cytosine-5-)-methyltransferase activity;GO:0016428 tRNA (cytidine-5-)-methyltransferase activity;GO:0003677 DNA binding;GO:0016427 tRNA (cytidine) methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008033 tRNA processing;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54JH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JL0-1", "uniprot_id": [ { "id": "NDOR1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JL0", "type": "external" } ], "mass": 73508.0, "length": 633, "protein_name": "NADPH-dependent diflavin oxidoreductase 1", "gene_name": "redC", "organism": "Cellular slime mold", "refseq_name": "NADPH-dependent diflavin oxidoreductase 1", "refseq_ac": [ { "id": "XP_636921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636921", "type": "external" } ], "gene_names_uniprotkb": "redC; DDB_G0287983; ndor1", "gene_names_refseq": "redC", "protein_names_uniprotkb": "NADPH-dependent diflavin oxidoreductase 1; 1.18.1.-; NADPH oxidoreductase C; NADPH-dependent FMN and FAD-containing oxidoreductase", "protein_names_refseq": "NADPH-dependent diflavin oxidoreductase 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287983)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18218133", "class_list": "", "function": "NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.18.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.18.1.-", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016491 oxidoreductase activity;GO:0016651 oxidoreductase activity, acting on NAD(P)H;GO:0010181 FMN binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54JL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JL3-1", "uniprot_id": [ { "id": "FTCD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JL3", "type": "external" } ], "mass": 59257.0, "length": 537, "protein_name": "Formimidoyltransferase-cyclodeaminase", "gene_name": "ftcd", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636918", "type": "external" } ], "gene_names_uniprotkb": "ftcd; DDB_G0287977", "gene_names_refseq": "ftcd", "protein_names_uniprotkb": "Formimidoyltransferase-cyclodeaminase; FTCD; Formiminotetrahydrofolate cyclodeaminase; Formiminotransferase-cyclodeaminase; Glutamate formiminotransferase; Glutamate formyltransferase; p60", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287977); (R-DDI-70921)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.5", "type": "external" }, { "id": "4.3.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.1.4", "type": "external" } ], "go_molecular_function": "GO:0005542 folic acid binding;GO:0030409 glutamate formimidoyltransferase activity;GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005814 centriole", "go_biological_process": "GO:0019556 L-histidine catabolic process to glutamate and formamide;GO:0019557 L-histidine catabolic process to glutamate and formate", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54JL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JL7-1", "uniprot_id": [ { "id": "CNRN_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JL7", "type": "external" } ], "mass": 71714.0, "length": 639, "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN", "gene_name": "cnrN", "organism": "Cellular slime mold", "refseq_name": "C2 tensin-type domain-containing protein", "refseq_ac": [ { "id": "XP_636914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636914", "type": "external" } ], "gene_names_uniprotkb": "cnrN; DDB_G0287969", "gene_names_refseq": "cnrN", "protein_names_uniprotkb": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; 3.1.3.67", "protein_names_refseq": "C2 tensin-type domain-containing protein; phosphatase tensin type domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287969)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18676953", "class_list": "", "function": "Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0016791 phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0042995 cell projection", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0046580 negative regulation of Ras protein signal transduction;GO:0030835 negative regulation of actin filament depolymerization;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54JL7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JT7-1", "uniprot_id": [ { "id": "NICA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JT7", "type": "external" } ], "mass": 74480.0, "length": 659, "protein_name": "Nicastrin", "gene_name": "ncstn", "organism": "Cellular slime mold", "refseq_name": "gamma-secretase subunit", "refseq_ac": [ { "id": "XP_637065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637065", "type": "external" } ], "gene_names_uniprotkb": "ncstn; DDB_G0287801", "gene_names_refseq": "ncstn", "protein_names_uniprotkb": "Nicastrin", "protein_names_refseq": "gamma-secretase subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287801); (R-DDI-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex (By similarity)., [UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0070765 gamma-secretase complex", "go_biological_process": "GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0016485 protein processing;GO:0006909 phagocytosis;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54JT7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JW0-1", "uniprot_id": [ { "id": "NDUF5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JW0", "type": "external" } ], "mass": 50194.0, "length": 436, "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "gene_name": "ndufaf5", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637042", "type": "external" } ], "gene_names_uniprotkb": "ndufaf5; DDB_G0287769", "gene_names_refseq": "", "protein_names_uniprotkb": "Arginine-hydroxylase NDUFAF5, mitochondrial; 1.-.-.-; 2.1.1.-; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5; Putative methyltransferase NDUFAF5", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287769)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;23536703", "class_list": "", "function": "Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages (PubMed:23536703). Probably acts as an arginine hydroxylase (By similarity). May also have methyltransferase activity., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0010507 negative regulation of autophagy;GO:0032259 methylation;GO:0042331 phototaxis;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54JW0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54JY7-1", "uniprot_id": [ { "id": "STX7A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54JY7", "type": "external" } ], "mass": 40219.0, "length": 356, "protein_name": "Syntaxin-7A", "gene_name": "syn7A", "organism": "Cellular slime mold", "refseq_name": "syntaxin 7", "refseq_ac": [ { "id": "XP_637015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637015", "type": "external" } ], "gene_names_uniprotkb": "syn7A; DDB_G0287733; syn7", "gene_names_refseq": "syn7A", "protein_names_uniprotkb": "Syntaxin-7A", "protein_names_refseq": "syntaxin 7; t-SNARE family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287733)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10978342;12175335;15875012", "class_list": "", "function": "Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for fusion of late endosomes with lysosomes and homotypic lysosomal fusion. May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005768 endosome;GO:0012505 endomembrane system;GO:0030666 endocytic vesicle membrane;GO:0010008 endosome membrane;GO:0031201 SNARE complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0008333 endosome to lysosome transport;GO:0016192 vesicle-mediated transport;GO:0006906 vesicle fusion;GO:0048278 vesicle docking", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54JY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54K32-1", "uniprot_id": [ { "id": "RGAA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54K32", "type": "external" } ], "mass": 94925.0, "length": 822, "protein_name": "Ras GTPase-activating-like protein rgaA", "gene_name": "rgaA", "organism": "Cellular slime mold", "refseq_name": "IQGAP-related protein", "refseq_ac": [ { "id": "XP_637132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637132", "type": "external" } ], "gene_names_uniprotkb": "rgaA; DDB_G0287585; DG1029; rasGAP1", "gene_names_refseq": "rgaA", "protein_names_uniprotkb": "Ras GTPase-activating-like protein rgaA; DGAP1; Developmental gene 1029 protein", "protein_names_refseq": "IQGAP-related protein; RasGTPase-activating protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287585); (R-DDI-5626467); (R-DDI-5674135); (R-DDI-6798695); (R-DDI-9013149); (R-DDI-9013404)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "10825297;11447112;15875012;8830653;9056774;9739079", "class_list": "", "function": "Part of signaling pathway that is required for completion of cytokinesis. gapA and rgaA control cortexillin localization to the cleavage furrow and hence may be involved in cleavage of the midbody in the final stage of cytokinesis by regulating the actin cytoskeleton. Forms a complex by linking activated rac1A to ctxA. Assembly of this complex is necessary for the recruitment of cortexillin to the midzone of a dividing cell. Overexpression leads to the suppression of the formation of cellular projections containing F-actin and to a defect in cytokinesis., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15815;P90531", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005516 calmodulin binding;GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0045180 basal cortex;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0032154 cleavage furrow;GO:0031254 cell trailing edge", "go_biological_process": "GO:0051495 positive regulation of cytoskeleton organization;GO:0000165 MAPK cascade;GO:0030036 actin cytoskeleton organization;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54K32-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54K81-1", "uniprot_id": [ { "id": "TALB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54K81", "type": "external" } ], "mass": 277729.0, "length": 2614, "protein_name": "Talin-B", "gene_name": "talB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637174", "type": "external" } ], "gene_names_uniprotkb": "talB; DDB_G0287505", "gene_names_refseq": "talB", "protein_names_uniprotkb": "Talin-B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287505); (R-DDI-114608)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10209124;15875012", "class_list": "", "function": "Actin-binding protein required for multicellular morphogenesis. Substrate of pkgB and/or pkbA., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O97054", "ec_number_list": [], "go_molecular_function": "GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0005938 cell cortex", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051017 actin filament bundle assembly;GO:0098609 cell-cell adhesion;GO:0048870 cell motility;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54K81-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KA7-1", "uniprot_id": [ { "id": "SECG_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KA7", "type": "external" } ], "mass": 107523.0, "length": 986, "protein_name": "Ankyrin repeat, PH and SEC7 domain containing protein secG", "gene_name": "secG", "organism": "Cellular slime mold", "refseq_name": "Arf guanyl-nucleotide exchange factor", "refseq_ac": [ { "id": "XP_637214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637214", "type": "external" } ], "gene_names_uniprotkb": "secG; DDB_G0287459", "gene_names_refseq": "secG", "protein_names_uniprotkb": "Ankyrin repeat, PH and SEC7 domain containing protein secG", "protein_names_refseq": "Arf guanyl-nucleotide exchange factor; SEC7-like domain-containing protein; ankyrin repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287459); (R-DDI-9907900)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P90525", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005764 lysosome", "go_biological_process": "GO:0006935 chemotaxis;GO:0030036 actin cytoskeleton organization;GO:0031589 cell-substrate adhesion;GO:0032012 regulation of ARF protein signal transduction;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54KA7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KB7-1", "uniprot_id": [ { "id": "DHE3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KB7", "type": "external" } ], "mass": 55042.0, "length": 502, "protein_name": "Glutamate dehydrogenase, mitochondrial", "gene_name": "gluD", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "gluD; DDB_G0287469", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutamate dehydrogenase, mitochondrial; 1.4.1.3; GDH", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287469); (R-DDI-8964539); (R-DDI-9837999)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "1402793;15875012;1952936", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "1.3.8.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.-", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "1.4.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.2", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.3.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.16", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004352 glutamate dehydrogenase (NAD+) activity;GO:0004353 glutamate dehydrogenase [NAD(P)+] activity;GO:0004354 glutamate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006538 L-glutamate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54KB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KE6-1", "uniprot_id": [ { "id": "MCCA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KE6", "type": "external" } ], "mass": 77089.0, "length": 699, "protein_name": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "gene_name": "mccA", "organism": "Cellular slime mold", "refseq_name": "3-methylcrotonyl-CoA:carbon dioxide ligase alpha subunit", "refseq_ac": [ { "id": "XP_637277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637277", "type": "external" } ], "gene_names_uniprotkb": "mccA; DDB_G0287377; mccc1", "gene_names_refseq": "mccA", "protein_names_uniprotkb": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; 6.4.1.4; MCCase subunit alpha", "protein_names_refseq": "3-methylcrotonyl-CoA:carbon dioxide ligase alpha subunit; methylcrotonyl-CoA carboxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287377); (R-DDI-196780); (R-DDI-70895)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.4.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.4", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004485 methylcrotonoyl-CoA carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006552 L-leucine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54KE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KF1-1", "uniprot_id": [ { "id": "FORC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KF1", "type": "external" } ], "mass": 131001.0, "length": 1158, "protein_name": "Formin-C", "gene_name": "forC", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_637272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637272", "type": "external" } ], "gene_names_uniprotkb": "forC; DDB_G0287295", "gene_names_refseq": "forC", "protein_names_uniprotkb": "Formin-C", "protein_names_refseq": "actin binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287295)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12538772;15726806;15740615;15875012;16762450", "class_list": "", "function": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q8IU40", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005911 cell-cell junction;GO:0044354 macropinosome", "go_biological_process": "GO:0007015 actin filament organization;GO:0051017 actin filament bundle assembly;GO:0010467 gene expression;GO:0031154 culmination involved in sorocarp development;GO:0044671 sorocarp spore cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54KF1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KF3-1", "uniprot_id": [ { "id": "ADA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KF3", "type": "external" } ], "mass": 87516.0, "length": 772, "protein_name": "Probable adenosine deaminase", "gene_name": "ada", "organism": "Cellular slime mold", "refseq_name": "adenosine deaminase", "refseq_ac": [ { "id": "XP_637270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637270", "type": "external" } ], "gene_names_uniprotkb": "ada; DDB_G0287371; add", "gene_names_refseq": "ada", "protein_names_uniprotkb": "Probable adenosine deaminase; 3.5.4.4; Adenosine aminohydrolase", "protein_names_refseq": "adenosine deaminase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287371); (R-DDI-74217); (R-DDI-9755088)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the hydrolytic deamination of adenosine. Plays an important role in purine metabolism and in adenosine homeostasis, and may thereby contribute to cellular signaling events (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" } ], "go_molecular_function": "GO:0004000 adenosine deaminase activity;GO:0046872 metal ion binding;GO:0000034 adenine deaminase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006154 adenosine catabolic process;GO:0009117 nucleotide metabolic process;GO:0046103 inosine biosynthetic process;GO:0043103 hypoxanthine salvage;GO:0060169 negative regulation of adenosine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54KF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KF7-1", "uniprot_id": [ { "id": "SIBA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KF7", "type": "external" } ], "mass": 208361.0, "length": 1927, "protein_name": "Integrin beta-like protein A", "gene_name": "sibA", "organism": "Cellular slime mold", "refseq_name": "integrin beta A-like protein", "refseq_ac": [ { "id": "XP_637266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637266", "type": "external" } ], "gene_names_uniprotkb": "sibA; DDB_G0287363", "gene_names_refseq": "sibA", "protein_names_uniprotkb": "Integrin beta-like protein A; 109 gene 1 protein", "protein_names_refseq": "integrin beta A-like protein; substrate adhesion molecule; type A von Willebrand factor domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287363)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15875012;16512674;16699495;2926809", "class_list": "", "function": "Implicated in cellular adhesion to substrate or phagocytic particles., [UniProtKB, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 6, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "Q0PL85;Q23848", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0055037 recycling endosome", "go_biological_process": "GO:0006909 phagocytosis;GO:0043652 engulfment of apoptotic cell;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54KF7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KI4-1", "uniprot_id": [ { "id": "EPS15_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KI4", "type": "external" } ], "mass": 131394.0, "length": 1196, "protein_name": "Epidermal growth factor receptor substrate 15 homolog", "gene_name": "eps15", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637239", "type": "external" } ], "gene_names_uniprotkb": "eps15; DDB_G0287325", "gene_names_refseq": "", "protein_names_uniprotkb": "Epidermal growth factor receptor substrate 15 homolog", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287325); (R-DDI-8856825); (R-DDI-8856828)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;19054384", "class_list": "", "function": "May be involved in clathrin-mediated endocytosis., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030122 AP-2 adaptor complex;GO:0030132 clathrin coat of coated pit", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0016197 endosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54KI4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KM0-1", "uniprot_id": [ { "id": "GEPH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KM0", "type": "external" } ], "mass": 78840.0, "length": 718, "protein_name": "Gephyrin", "gene_name": "gphn", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637337", "type": "external" } ], "gene_names_uniprotkb": "gphn; DDB_G0287261; gph", "gene_names_refseq": "gphn", "protein_names_uniprotkb": "Gephyrin; Domain E; Domain G; Putative glycine receptor-tubulin linker protein homolog", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287261); (R-DDI-947581)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released., [UniProtKB, UniProtKB]; Microtubule-associated protein involved in membrane protein-cytoskeleton interactions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.10.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.10.1.1", "type": "external" }, { "id": "2.7.7.75", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.75", "type": "external" } ], "go_molecular_function": "GO:0061598 molybdopterin adenylyltransferase activity;GO:0061599 molybdopterin molybdotransferase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54KM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KM6-1", "uniprot_id": [ { "id": "KAT_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KM6", "type": "external" } ], "mass": 48553.0, "length": 435, "protein_name": "Kynurenine--oxoglutarate transaminase", "gene_name": "ccbl", "organism": "Cellular slime mold", "refseq_name": "cysteine-S-conjugate beta-lyase", "refseq_ac": [ { "id": "XP_637331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637331", "type": "external" } ], "gene_names_uniprotkb": "ccbl; DDB_G0287269; kat", "gene_names_refseq": "ccbl", "protein_names_uniprotkb": "Kynurenine--oxoglutarate transaminase; 2.6.1.64; 2.6.1.7; 4.4.1.13; Glutamine transaminase K; Glutamine--phenylpyruvate transaminase; Kynurenine aminotransferase", "protein_names_refseq": "cysteine-S-conjugate beta-lyase; kynurenine aminotransferase; kynurenine-oxoglutarate transaminase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287269); (R-DDI-71240); (R-DDI-8964208); (R-DDI-8964539)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.64", "type": "external" }, { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0047316 glutamine-phenylpyruvate transaminase activity;GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0008483 transaminase activity;GO:0047804 cysteine-S-conjugate beta-lyase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0097053 L-kynurenine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54KM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KQ7-1", "uniprot_id": [ { "id": "SPAST_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KQ7", "type": "external" } ], "mass": 73762.0, "length": 655, "protein_name": "Spastin", "gene_name": "DDB_G0287165", "organism": "Cellular slime mold", "refseq_name": "AAA ATPase domain-containing protein", "refseq_ac": [ { "id": "XP_637373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637373", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0287165", "gene_names_refseq": "", "protein_names_uniprotkb": "Spastin; 5.6.1.1", "protein_names_refseq": "AAA ATPase domain-containing protein; MIT domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287165); (R-DDI-9668328)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.1", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" } ], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0015631 tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0051233 spindle midzone", "go_biological_process": "GO:0051013 microtubule severing;GO:0031117 positive regulation of microtubule depolymerization;GO:0006998 nuclear envelope organization;GO:0034214 protein hexamerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54KQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54KV6-1", "uniprot_id": [ { "id": "GPA3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54KV6", "type": "external" } ], "mass": 64973.0, "length": 570, "protein_name": "Guanine nucleotide-binding protein alpha-3 subunit", "gene_name": "gpaC", "organism": "Cellular slime mold", "refseq_name": "G-protein subunit alpha 3", "refseq_ac": [ { "id": "XP_637414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637414", "type": "external" } ], "gene_names_uniprotkb": "gpaC; DDB_G0287031; Ga3", "gene_names_refseq": "gpaC", "protein_names_uniprotkb": "Guanine nucleotide-binding protein alpha-3 subunit; G alpha-3", "protein_names_refseq": "G-protein subunit alpha 3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287031); (R-DDI-112043); (R-DDI-170670); (R-DDI-202040); (R-DDI-2485179); (R-DDI-2514859); (R-DDI-399997); (R-DDI-4086398); (R-DDI-416476); (R-DDI-416482); (R-DDI-418592); (R-DDI-418594); (R-DDI-434316); (R-DDI-9013149); (R-DDI-9856530)", "pathway_count": 15, "publication_count": 2, "publication_id_list": "15875012;9373143", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-3 plays a role in development. G alpha-3 mutants fail to aggregate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q94470", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0008603 cAMP-dependent protein kinase regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0010468 regulation of gene expression;GO:0060176 regulation of aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54KV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54L53-1", "uniprot_id": [ { "id": "GRLD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54L53", "type": "external" } ], "mass": 87715.0, "length": 791, "protein_name": "Metabotropic glutamate receptor-like protein D", "gene_name": "grlD", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family 3 protein 4", "refseq_ac": [ { "id": "XP_637510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637510", "type": "external" } ], "gene_names_uniprotkb": "grlD; DDB_G0286895", "gene_names_refseq": "grlD", "protein_names_uniprotkb": "Metabotropic glutamate receptor-like protein D", "protein_names_refseq": "G-protein-coupled receptor family 3 protein 4", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286895)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;16735079;17501984", "class_list": "", "function": "", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0097648 G protein-coupled receptor complex", "go_biological_process": "GO:0051702 biological process involved in interaction with symbiont;GO:0007186 G protein-coupled receptor signaling pathway;GO:0009617 response to bacterium;GO:0060245 detection of cell density;GO:0110094 polyphosphate-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54L53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54L85-1", "uniprot_id": [ { "id": "NSDHL_DICDI", "url": "https://www.uniprot.org/uniprot/Q54L85", "type": "external" } ], "mass": 36765.0, "length": 328, "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "nsdhl", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637518", "type": "external" } ], "gene_names_uniprotkb": "nsdhl; DDB_G0286833", "gene_names_refseq": "", "protein_names_uniprotkb": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; 1.1.1.170", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286833)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.170", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.170", "type": "external" } ], "go_molecular_function": "GO:0008460 dTDP-glucose 4,6-dehydratase activity;GO:0102175 3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54L85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54LJ3-1", "uniprot_id": [ { "id": "TS101_DICDI", "url": "https://www.uniprot.org/uniprot/Q54LJ3", "type": "external" } ], "mass": 54919.0, "length": 478, "protein_name": "ESCRT-I complex subunit tsg101", "gene_name": "tsg101", "organism": "Cellular slime mold", "refseq_name": "tumor susceptibility gene 101 protein", "refseq_ac": [ { "id": "XP_637568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637568", "type": "external" } ], "gene_names_uniprotkb": "tsg101; DDB_G0286797", "gene_names_refseq": "tsg101", "protein_names_uniprotkb": "ESCRT-I complex subunit tsg101", "protein_names_refseq": "tumor susceptibility gene 101 protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286797); (R-DDI-917729)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. Acts as a negative growth regulator (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0031902 late endosome membrane;GO:0000813 ESCRT I complex;GO:0140220 pathogen-containing vacuole", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0015031 protein transport;GO:0050830 defense response to Gram-positive bacterium;GO:0009611 response to wounding;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54LJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54LP3-1", "uniprot_id": [ { "id": "DPM1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54LP3", "type": "external" } ], "mass": 28698.0, "length": 254, "protein_name": "Dolichol-phosphate mannosyltransferase subunit 1", "gene_name": "dpm1", "organism": "Cellular slime mold", "refseq_name": "dolichol-phosphate-mannose synthase", "refseq_ac": [ { "id": "XP_637689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637689", "type": "external" } ], "gene_names_uniprotkb": "dpm1; DDB_G0286519; dgtB", "gene_names_refseq": "dgtB", "protein_names_uniprotkb": "Dolichol-phosphate mannosyltransferase subunit 1; 2.4.1.83; DPM synthase subunit 1; Dolichol-phosphate mannose synthase subunit 1; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; MPD synthase subunit 1; Mannose-P-dolichol synthase subunit 1", "protein_names_refseq": "dolichol-phosphate-mannose synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286519); (R-DDI-162699)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "glycogene;glycosyltransferase", "function": "Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.83", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.83", "type": "external" } ], "go_molecular_function": "GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0035269 protein O-linked glycosylation via mannose;GO:0006506 GPI anchor biosynthetic process;GO:0180047 dolichol phosphate mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54LP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54LQ6-1", "uniprot_id": [ { "id": "ITPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54LQ6", "type": "external" } ], "mass": 21730.0, "length": 194, "protein_name": "Inosine triphosphate pyrophosphatase", "gene_name": "itpa", "organism": "Cellular slime mold", "refseq_name": "inosine triphosphatase", "refseq_ac": [ { "id": "XP_637700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637700", "type": "external" } ], "gene_names_uniprotkb": "itpa; DDB_G0286495", "gene_names_refseq": "itpa", "protein_names_uniprotkb": "Inosine triphosphate pyrophosphatase; 3.6.1.66; ITPase; Inosine triphosphatase; NTPase; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; XTP/dITP diphosphatase", "protein_names_refseq": "inosine triphosphatase; inosine triphosphate pyrophosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286495); (R-DDI-74259); (R-DDI-9755088)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.66", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.66", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0047429 nucleoside triphosphate diphosphatase activity;GO:0035870 dITP diphosphatase activity;GO:0036220 ITP diphosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009117 nucleotide metabolic process;GO:0009143 nucleoside triphosphate catabolic process;GO:0009204 deoxyribonucleoside triphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54LQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54LR6-1", "uniprot_id": [ { "id": "Y6481_DICDI", "url": "https://www.uniprot.org/uniprot/Q54LR6", "type": "external" } ], "mass": 70465.0, "length": 605, "protein_name": "Probable serine/threonine-protein kinase DDB_G0286481", "gene_name": "DDB_G0286481", "organism": "Cellular slime mold", "refseq_name": "CK2 family protein kinase", "refseq_ac": [ { "id": "XP_637764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637764", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0286481", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0286481; 2.7.11.1", "protein_names_refseq": "CK2 family protein kinase; protein kinase, CMGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286481); (R-DDI-2514853); (R-DDI-6804756); (R-DDI-8948751)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane;GO:0005956 protein kinase CK2 complex", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0006974 DNA damage response;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54LR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54LT0-1", "uniprot_id": [ { "id": "MCU_DICDI", "url": "https://www.uniprot.org/uniprot/Q54LT0", "type": "external" } ], "mass": 31756.0, "length": 275, "protein_name": "Calcium uniporter protein, mitochondrial", "gene_name": "mcu", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637750", "type": "external" } ], "gene_names_uniprotkb": "mcu; DDB0186972", "gene_names_refseq": "", "protein_names_uniprotkb": "Calcium uniporter protein, mitochondrial; DdMCU", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286429); (R-DDI-8949215)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15875012;24889638;32258880;33296646", "class_list": "", "function": "Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria (PubMed:24889638, PubMed:33296646). Constitutes a pore-forming and calcium-conducting subunit (PubMed:24889638, PubMed:33296646). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (PubMed:24889638). Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit (PubMed:33296646)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005509 calcium ion binding;GO:0015292 uniporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:1990246 uniplex complex", "go_biological_process": "GO:0036444 calcium import into the mitochondrion;GO:0051560 mitochondrial calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54LT0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54LY5-1", "uniprot_id": [ { "id": "XRCC5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54LY5", "type": "external" } ], "mass": 90938.0, "length": 796, "protein_name": "X-ray repair cross-complementing protein 5", "gene_name": "ku80", "organism": "Cellular slime mold", "refseq_name": "ATP-dependent DNA helicase", "refseq_ac": [ { "id": "XP_637846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637846", "type": "external" } ], "gene_names_uniprotkb": "ku80; DDB_G0286303", "gene_names_refseq": "ku80", "protein_names_uniprotkb": "X-ray repair cross-complementing protein 5; 3.6.4.-; ATP-dependent DNA helicase 2 subunit ku80", "protein_names_refseq": "ATP-dependent DNA helicase; DNA-dependent protein kinase subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286303); (R-DDI-5693571); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0042162 telomeric DNA binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0006974 DNA damage response;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54LY5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54M18-1", "uniprot_id": [ { "id": "ARG56_DICDI", "url": "https://www.uniprot.org/uniprot/Q54M18", "type": "external" } ], "mass": 92818.0, "length": 847, "protein_name": "Bifunctional protein argC, mitochondrial", "gene_name": "argC", "organism": "Cellular slime mold", "refseq_name": "N-acetyl-gamma-glutamyl-phosphate reductase", "refseq_ac": [ { "id": "XP_637813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637813", "type": "external" } ], "gene_names_uniprotkb": "argC; DDB_G0286257", "gene_names_refseq": "argC", "protein_names_uniprotkb": "Bifunctional protein argC, mitochondrial; AGK; N-acetyl-L-glutamate 5-phosphotransferase; N-acetyl-glutamate semialdehyde dehydrogenase; NAG kinase; NAGSA dehydrogenase", "protein_names_refseq": "N-acetyl-gamma-glutamyl-phosphate reductase; acetylglutamate kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286257); (R-DDI-70635)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.38", "type": "external" }, { "id": "2.7.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0051287 NAD binding;GO:0070401 NADP+ binding;GO:0003942 N-acetyl-gamma-glutamyl-phosphate reductase activity;GO:0003991 acetylglutamate kinase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006526 L-arginine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54M18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54M25-1", "uniprot_id": [ { "id": "PONB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54M25", "type": "external" } ], "mass": 15188.0, "length": 145, "protein_name": "Ponticulin-like protein B", "gene_name": "ponB", "organism": "Cellular 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"2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal 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(ddi:DDB_G0286075); (R-DDI-156827); (R-DDI-1799339); (R-DDI-6791226); (R-DDI-72689); (R-DDI-72695); (R-DDI-72702); (R-DDI-72706); (R-DDI-975956); (R-DDI-975957); (R-DDI-9954714); (R-DDI-9954716)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. 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"https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity;GO:0042162 telomeric DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0045893 positive regulation of DNA-templated transcription;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54MA9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ME1-1", "uniprot_id": [ { "id": "GMSA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ME1", "type": "external" } ], "mass": 48674.0, "length": 448, "protein_name": "Gamete and mating-type specific protein A", "gene_name": "gmsA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637893", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637893", "type": "external" } ], "gene_names_uniprotkb": "gmsA; DDB_G0286015", "gene_names_refseq": "gmsA", "protein_names_uniprotkb": "Gamete and mating-type specific protein A; 3.4.22.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286015); (R-DDI-2132295); (R-DDI-5683826); (R-DDI-6798695)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "12963116;15875012", "class_list": "", "function": "Thiol protease that seems to be involved in the sexual development., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.5.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.-.-", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity;GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:2001235 positive regulation of apoptotic signaling pathway;GO:0051603 proteolysis involved in protein catabolic process;GO:0007618 mating;GO:0000747 conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54ME1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54MH2-1", "uniprot_id": [ { "id": "VINC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54MH2", "type": "external" } ], "mass": 92839.0, "length": 842, "protein_name": "Probable vinculin", "gene_name": "ctnnA", "organism": "Cellular slime mold", "refseq_name": "vinculin A", "refseq_ac": [ { "id": "XP_638018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638018", "type": "external" } ], "gene_names_uniprotkb": "ctnnA; DDB_G0285939; vcl; vinA", "gene_names_refseq": "vinA", "protein_names_uniprotkb": "Probable vinculin; Ddalpha-catenin", "protein_names_refseq": "vinculin A", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285939)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15875012;19065153;21393547;22902739", "class_list": "", "function": "Involved in cell adhesion. Thought to play an important role in cytokinesis B, probably by providing substrate adhesion and traction forces. Required to organize and polarize the tip epithelium during cytokinesis. Required for the normal distribution of myosin in the tip epithelium. Involved in the localization of ctxA, ctxB, dcsA, exoc6 and rgaA. Thought to form a complex with ctxA, ctxB, and rgaA which regulates myosin accumulation to the apical plasma membrane., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0008013 beta-catenin binding;GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0045180 basal cortex;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0051495 positive regulation of cytoskeleton organization;GO:0007155 cell adhesion;GO:0051017 actin filament bundle assembly;GO:0031032 actomyosin structure organization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54MH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54MH3-1", "uniprot_id": [ { "id": "DHX16_DICDI", "url": "https://www.uniprot.org/uniprot/Q54MH3", "type": "external" } ], "mass": 126564.0, "length": 1106, "protein_name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "gene_name": "dhx16", "organism": "Cellular slime mold", "refseq_name": "DEAD/DEAH box helicase", "refseq_ac": [ { "id": "XP_638017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638017", "type": "external" } ], "gene_names_uniprotkb": "dhx16; DDB_G0285937", "gene_names_refseq": "dhx16", "protein_names_uniprotkb": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; 3.6.4.13; DEAH-box protein 16", "protein_names_refseq": "DEAD/DEAH box helicase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285937)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54MH3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54MH8-1", "uniprot_id": [ { "id": "DLPB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54MH8", "type": "external" } ], "mass": 92714.0, "length": 808, "protein_name": "Dynamin-like protein B", "gene_name": "dlpB", "organism": "Cellular slime mold", "refseq_name": "dynamin like protein", "refseq_ac": [ { "id": "XP_638012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638012", "type": "external" } ], "gene_names_uniprotkb": "dlpB; DDB_G0285931", "gene_names_refseq": "dlpB", "protein_names_uniprotkb": "Dynamin-like protein B; 3.6.5.5", "protein_names_refseq": "dynamin like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285931)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18809930", "class_list": "", "function": "Involved in cytokinesis. May hydrolyze GTP., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016020 membrane;GO:0032154 cleavage furrow", "go_biological_process": "GO:0007015 actin filament organization;GO:0000281 mitotic cytokinesis;GO:0061952 midbody abscission;GO:1905345 protein localization to cleavage furrow", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54MH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54MI3-1", "uniprot_id": [ { "id": "SUN2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54MI3", "type": "external" } ], "mass": 146049.0, "length": 1278, "protein_name": "SUN domain-containing protein 2", "gene_name": "sun2", "organism": "Cellular slime mold", "refseq_name": "SUN domain-containing protein 2", "refseq_ac": [ { "id": "XP_638007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638007", "type": "external" } ], "gene_names_uniprotkb": "sun2; DDB_G0285925", "gene_names_refseq": "sun2", "protein_names_uniprotkb": "SUN domain-containing protein 2", "protein_names_refseq": "SUN domain-containing protein 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285925)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 30, "predicted_n_glycosites": 29, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 30, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0031965 nuclear membrane;GO:0005773 vacuole", "go_biological_process": "GO:0000281 mitotic cytokinesis;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54MI3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54MY9-1", "uniprot_id": [ { "id": "MKCA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54MY9", "type": "external" } ], "mass": 97846.0, "length": 860, "protein_name": "Probable serine/threonine-protein kinase mkcA", "gene_name": "mkcA", "organism": "Cellular slime mold", "refseq_name": "MKC subfamily protein kinase", "refseq_ac": [ { "id": "XP_638154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638154", "type": "external" } ], "gene_names_uniprotkb": "mkcA; DDB_G0285427; DG1023", "gene_names_refseq": "mkcA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase mkcA; 2.7.11.1; MAP kinase cascade A", "protein_names_refseq": "MKC subfamily protein kinase; STE20 family protein kinase; protein kinase, STE group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285427)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;8986798", "class_list": "", "function": "Coordinates organism morphology with cellular differentiation during development. Negative regulator of sporulation, synchronizing encapsulation with culmination. May have an additional function in prestalk cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q23916", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0045595 regulation of cell differentiation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54MY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54N00-1", "uniprot_id": [ { "id": "FORH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54N00", "type": "external" } ], "mass": 121580.0, "length": 1087, "protein_name": "Formin-H", "gene_name": "forH", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_638143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638143", "type": "external" } ], "gene_names_uniprotkb": "forH; DDB_G0285589; dia2; drf2", "gene_names_refseq": "forH", "protein_names_uniprotkb": "Formin-H; Diaphanous-related formin dia2; dDia2", "protein_names_refseq": "actin binding protein; diaphanous-related formin", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285589)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15740615;15875012;15908944;16675552;16762450", "class_list": "", "function": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments. Important for cell migration and formation, elongation and maintenance of filopodia. Specifically controls filopodial dynamics by regulating actin turnover at the barbed ends of actin filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5TJB8", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0030175 filopodium;GO:0032433 filopodium tip;GO:0031254 cell trailing edge", "go_biological_process": "GO:0070060 'de novo' actin filament nucleation;GO:0031268 pseudopodium organization;GO:0046847 filopodium assembly;GO:0000902 cell morphogenesis;GO:0030866 cortical actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54N00-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54N49-1", "uniprot_id": [ { "id": "INO1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54N49", "type": "external" } ], "mass": 56847.0, "length": 511, "protein_name": "Inositol-3-phosphate synthase", "gene_name": "ino1", "organism": "Cellular slime mold", "refseq_name": "inositol-3-phosphate synthase", "refseq_ac": [ { "id": "XP_638094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638094", "type": "external" } ], "gene_names_uniprotkb": "ino1; DDB_G0285505", "gene_names_refseq": "ino1", "protein_names_uniprotkb": "Inositol-3-phosphate synthase; 5.5.1.4; IPS; MI-1-P synthase; MIP synthase; Myo-inositol 1-phosphate synthase", "protein_names_refseq": "inositol-3-phosphate synthase; myo-inositol-1-phosphate synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285505); (R-DDI-1855183)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.5.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.5.1.4", "type": "external" } ], "go_molecular_function": "GO:0004512 inositol-3-phosphate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006914 autophagy;GO:0000281 mitotic cytokinesis;GO:0031589 cell-substrate adhesion;GO:1903725 regulation of phospholipid metabolic process;GO:0006021 inositol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54N49-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54N97-1", "uniprot_id": [ { "id": "DPOD1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54N97", "type": "external" } ], "mass": 125346.0, "length": 1104, "protein_name": "DNA polymerase delta catalytic subunit", "gene_name": "pold1", "organism": "Cellular slime mold", "refseq_name": "DNA polymerase delta catalytic subunit", "refseq_ac": [ { "id": "XP_638283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638283", "type": "external" } ], "gene_names_uniprotkb": "pold1; DDB_G0285381", "gene_names_refseq": "polD1", "protein_names_uniprotkb": "DNA polymerase delta catalytic subunit; 2.7.7.7; DNA polymerase III", "protein_names_refseq": "DNA polymerase delta catalytic subunit; DNA polymerase delta subunit 1; DNA polymerase subunit delta p125", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285381); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-69091); (R-DDI-69166); (R-DDI-69183)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008296 3'-5'-DNA exonuclease activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0043625 delta DNA polymerase complex", "go_biological_process": "GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006287 base-excision repair, gap-filling;GO:0045004 DNA replication proofreading;GO:0006281 DNA repair;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54N97-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NA3-1", "uniprot_id": [ { "id": "ATG9_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NA3", "type": "external" } ], "mass": 81314.0, "length": 699, "protein_name": "Autophagy-related protein 9", "gene_name": "atg9", "organism": "Cellular slime mold", "refseq_name": "autophagy protein 9", "refseq_ac": [ { "id": "XP_638277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638277", "type": "external" } ], "gene_names_uniprotkb": "atg9; DDB_G0285323; apg9", "gene_names_refseq": "atg9", "protein_names_uniprotkb": "Autophagy-related protein 9", "protein_names_refseq": "autophagy protein 9", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285323); (R-DDI-1632852)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "12626495;15875012;20070309;22575510", "class_list": "", "function": "Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway (PubMed:12626495, PubMed:22575510)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q86CR7", "ec_number_list": [], "go_molecular_function": "GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005874 microtubule;GO:0030659 cytoplasmic vesicle membrane;GO:0005815 microtubule organizing center;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0090382 phagosome maturation;GO:0006909 phagocytosis;GO:0009617 response to bacterium;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034497 protein localization to phagophore assembly site", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54NA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ND5-1", "uniprot_id": [ { "id": "MINP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ND5", "type": "external" } ], "mass": 70382.0, "length": 635, "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "organism": "Cellular slime mold", "refseq_name": "multiple inositol polyphosphate phosphatase", "refseq_ac": [ { "id": "XP_638245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638245", "type": "external" } ], "gene_names_uniprotkb": "mipp1; DDB_G0285339", "gene_names_refseq": "mipp1", "protein_names_uniprotkb": "Multiple inositol polyphosphate phosphatase 1; 2,3-BPG phosphatase; 2,3-bisphosphoglycerate 3-phosphatase; 3.1.3.62; 3.1.3.80; Ddmipp1", "protein_names_refseq": "multiple inositol polyphosphate phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285339); (R-DDI-1855231)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;18413611", "class_list": "", "function": "Probable multiple inositol polyphosphate phosphatase that hydrolyzes 1D-myo-inositol 1,3,4,5,6-pentakisphosphate (InsP5[2OH]) and 1D-myo-inositol hexakisphosphate (InsP6) to a range of less phosphorylated inositol phosphates. This regulates the availability of these various small molecule second messengers and metal chelators which control many aspects of cell physiology (By similarity). May have a dual substrate specificity, and function as a 2,3-bisphosphoglycerate 3-phosphatase hydrolyzing 2,3-bisphosphoglycerate to 2-phosphoglycerate. 2,3-bisphosphoglycerate (BPG) is formed as part of the Rapoport-Luebering glycolytic bypass (PubMed:18413611)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.62", "type": "external" }, { "id": "3.1.3.80", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.80", "type": "external" } ], "go_molecular_function": "GO:0003993 acid phosphatase activity;GO:0034417 bisphosphoglycerate 3-phosphatase activity;GO:0052745 inositol phosphate phosphatase activity;GO:0016158 inositol hexakisphosphate 3-phosphatase activity;GO:0004446 inositol hexakisphosphate phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0010226 response to lithium ion;GO:0006007 glucose catabolic process;GO:0032957 inositol trisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54ND5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NE6-1", "uniprot_id": [ { "id": "PGAM_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NE6", "type": "external" } ], "mass": 28480.0, "length": 249, "protein_name": "Probable phosphoglycerate mutase", "gene_name": "gpmA", "organism": "Cellular slime mold", "refseq_name": "phosphoglycerate mutase", "refseq_ac": [ { "id": "XP_638289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638289", "type": "external" } ], "gene_names_uniprotkb": "gpmA; DDB_G0285311; pgam", "gene_names_refseq": "gpmA", "protein_names_uniprotkb": "Probable phosphoglycerate mutase; 5.4.2.11; 5.4.2.4; BPG-dependent PGAM; dPGM", "protein_names_refseq": "phosphoglycerate mutase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285311); (R-DDI-6798695); (R-DDI-70171); (R-DDI-70263)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004082 bisphosphoglycerate mutase activity;GO:0004619 phosphoglycerate mutase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54NE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NF8-1", "uniprot_id": [ { "id": "SCAR_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NF8", "type": "external" } ], "mass": 48403.0, "length": 443, "protein_name": "Protein SCAR", "gene_name": "scrA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_638311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638311", "type": "external" } ], "gene_names_uniprotkb": "scrA; DDB_G0285253", "gene_names_refseq": "scrA", "protein_names_uniprotkb": "Protein SCAR; Suppressor of cAMP receptor", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285253); (R-DDI-2029482); (R-DDI-5663213); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "11683394;12956949;15875012;16822579;17314411;9732292", "class_list": "", "function": "Involved in regulation of actin and microtubule organization. Regulates phagocytosis and macropinocytosis., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XYA8", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003779 actin binding;GO:0034237 protein kinase A regulatory subunit binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005911 cell-cell junction;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0031252 cell leading edge", "go_biological_process": "GO:0008064 regulation of actin polymerization or depolymerization;GO:0007015 actin filament organization;GO:0006909 phagocytosis;GO:0030036 actin cytoskeleton organization;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54NF8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NJ8-1", "uniprot_id": [ { "id": "HPRT_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NJ8", "type": "external" } ], "mass": 20536.0, "length": 180, "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "hprT", "organism": "Cellular slime mold", "refseq_name": "hypoxanthine phosphoribosyltransferase", "refseq_ac": [ { "id": "XP_638364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638364", "type": "external" } ], "gene_names_uniprotkb": "hprT; DDB_G0285193", "gene_names_refseq": "hprT", "protein_names_uniprotkb": "Hypoxanthine-guanine phosphoribosyltransferase; 2.4.2.8; HGPRTase; HGPRT", "protein_names_refseq": "hypoxanthine phosphoribosyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285193); (R-DDI-74217); (R-DDI-9748787)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;6428268", "class_list": "", "function": "Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.8", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0000166 nucleotide binding;GO:0004422 hypoxanthine phosphoribosyltransferase activity;GO:0052657 guanine phosphoribosyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032264 IMP salvage;GO:0006166 purine ribonucleoside salvage;GO:0006178 guanine salvage;GO:0046100 hypoxanthine metabolic process;GO:0032263 GMP salvage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54NJ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NL4-1", "uniprot_id": [ { "id": "VMP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NL4", "type": "external" } ], "mass": 45612.0, "length": 403, "protein_name": "Vacuole membrane protein 1 homolog", "gene_name": "vmp1", "organism": "Cellular slime mold", "refseq_name": "TMEM49 family protein", "refseq_ac": [ { "id": "XP_638348", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638348", "type": "external" } ], "gene_names_uniprotkb": "vmp1; DDB_G0285175; tmem49", "gene_names_refseq": "vmp1", "protein_names_uniprotkb": "Vacuole membrane protein 1 homolog; Transmembrane protein 49 homolog", "protein_names_refseq": "TMEM49 family protein; transmembrane protein; vacuole membrane protein 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285175)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18550798", "class_list": "", "function": "Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes (By similarity). Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted (By similarity). In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required (PubMed:18550798)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006869 lipid transport;GO:0006914 autophagy;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54NL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NM6-1", "uniprot_id": [ { "id": "MOCS1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NM6", "type": "external" } ], "mass": 71582.0, "length": 630, "protein_name": "Molybdenum cofactor biosynthesis protein 1", "gene_name": "mocs1", "organism": "Cellular slime mold", "refseq_name": "molybdenum cofactor synthesis 1", "refseq_ac": [ { "id": "XP_639890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639890", "type": "external" } ], "gene_names_uniprotkb": "mocs1; DDB_G0285137", "gene_names_refseq": "mocs1", "protein_names_uniprotkb": "Molybdenum cofactor biosynthesis protein 1; MOCS1A; MOCS1B; Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor biosynthesis protein C", "protein_names_refseq": "molybdenum cofactor synthesis 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285137); (R-DDI-947581)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Isoform mocs1a and isoform mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). mocs1a catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.99.22", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.99.22", "type": "external" }, { "id": "4.6.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.17", "type": "external" } ], "go_molecular_function": "GO:0061798 GTP 3',8'-cyclase activity;GO:0061799 cyclic pyranopterin monophosphate synthase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54NM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NP6-1", "uniprot_id": [ { "id": "SNAA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NP6", "type": "external" } ], "mass": 32407.0, "length": 291, "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "snpA", "organism": "Cellular slime mold", "refseq_name": "soluble NSF attachment protein alpha isoform", "refseq_ac": [ { "id": "XP_639870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639870", "type": "external" } ], "gene_names_uniprotkb": "snpA; DDB_G0285111", "gene_names_refseq": "snpA", "protein_names_uniprotkb": "Alpha-soluble NSF attachment protein; N-ethylmaleimide-sensitive factor attachment protein alpha; SNAP-alpha", "protein_names_refseq": "soluble NSF attachment protein alpha isoform", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285111); (R-DDI-204005); (R-DDI-6807878); (R-DDI-6811434); (R-DDI-6811438); (R-DDI-6811440)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "10727946;12175335;15875012;16926386", "class_list": "", "function": "May be required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity). Involved in vesicle fusion with nsfA and probably SNARE proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0005483 soluble NSF attachment protein activity", "go_cellular_component": "GO:0030659 cytoplasmic vesicle membrane;GO:0045335 phagocytic vesicle;GO:0031201 SNARE complex", "go_biological_process": "GO:0035494 SNARE complex disassembly;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54NP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NP8-1", "uniprot_id": [ { "id": "KIF4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NP8", "type": "external" } ], "mass": 222483.0, "length": 1922, "protein_name": "Kinesin-related protein 4", "gene_name": "kif4", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 4", "refseq_ac": [ { "id": "XP_639868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639868", "type": "external" } ], "gene_names_uniprotkb": "kif4; DDB_G0285101; K4; ksnD", "gene_names_refseq": "kif4", "protein_names_uniprotkb": "Kinesin-related protein 4; Kinesin family member 4; Kinesin-7", "protein_names_refseq": "kinesin family member 4", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285101); (R-DDI-983189)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14641909;15875012;18430243;9693369", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with dynein in organizing spindle assembly during cell division., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15719;Q869B8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0043515 kinetochore binding", "go_cellular_component": "GO:0005874 microtubule;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54NP8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NU0-1", "uniprot_id": [ { "id": "FEN1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NU0", "type": "external" } ], "mass": 43124.0, "length": 384, "protein_name": "Flap endonuclease 1", "gene_name": "repG", "organism": "Cellular slime mold", "refseq_name": "flap structure specific endonuclease 1", "refseq_ac": [ { "id": "XP_639977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639977", "type": "external" } ], "gene_names_uniprotkb": "repG; DDB_G0284987", "gene_names_refseq": "repG", "protein_names_uniprotkb": "Flap endonuclease 1; 3.1.-.-; FEN-1; Flap structure-specific endonuclease 1", "protein_names_refseq": "flap structure specific endonuclease 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284987); (R-DDI-110362); (R-DDI-69166)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.2.1.143", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.143", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003677 DNA binding;GO:0030145 manganese ion binding;GO:0004527 exonuclease activity;GO:0008409 5'-3' exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006281 DNA repair;GO:0006284 base-excision repair;GO:0006260 DNA replication;GO:0043137 DNA replication, removal of RNA primer", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54NU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NW4-1", "uniprot_id": [ { "id": "LIMB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NW4", "type": "external" } ], "mass": 60341.0, "length": 553, "protein_name": "LIM domain-containing protein B", "gene_name": "limB", "organism": "Cellular slime mold", "refseq_name": "LIM-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_639953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639953", "type": "external" } ], "gene_names_uniprotkb": "limB; DDB_G0284863; lim2; paxA", "gene_names_refseq": "limB", "protein_names_uniprotkb": "LIM domain-containing protein B; Paxillin-A", "protein_names_refseq": "LIM-type zinc finger-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284863); (R-DDI-8849471)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10749929;15875012;16155255", "class_list": "", "function": "Regulates and controls rearrangements of the actin cytoskeleton. Required for tip formation, morphogenesis, cell adhesion and motility, chemotaxis and aggregates formation. May function downstream of paxB., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9U628", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005938 cell cortex", "go_biological_process": "GO:0006935 chemotaxis;GO:0007155 cell adhesion;GO:0016477 cell migration;GO:0032060 bleb assembly;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54NW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54NW7-1", "uniprot_id": [ { "id": "VAM7A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54NW7", "type": "external" } ], "mass": 24772.0, "length": 216, "protein_name": "Vesicle-associated membrane protein 7A", "gene_name": "vamp7A", "organism": "Cellular slime mold", "refseq_name": "longin domain-containing protein", "refseq_ac": [ { "id": "XP_639950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639950", "type": "external" } ], "gene_names_uniprotkb": "vamp7A; DDB_G0284951; vamp7", "gene_names_refseq": "vamp7A", "protein_names_uniprotkb": "Vesicle-associated membrane protein 7A", "protein_names_refseq": "longin domain-containing protein; synaptobrevin domain-containing protein; v-SNARE family protein; vesicle-associated membrane protein 7", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284951); (R-DDI-199992)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12175335;15875012", "class_list": "", "function": "Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030658 transport vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0008333 endosome to lysosome transport;GO:0016192 vesicle-mediated transport;GO:0006906 vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54NW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54P47-1", "uniprot_id": [ { "id": "NDRC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54P47", "type": "external" } ], "mass": 149360.0, "length": 1335, "protein_name": "Probable serine/threonine-protein kinase ndrC", "gene_name": "ndrC", "organism": "Cellular slime mold", "refseq_name": "NDR family protein kinase", "refseq_ac": [ { "id": "XP_638411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638411", "type": "external" } ], "gene_names_uniprotkb": "ndrC; DDB_G0284839", "gene_names_refseq": "ndrC", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase ndrC; 2.7.11.1; Nuclear DBF2-related kinase C", "protein_names_refseq": "NDR family protein kinase; protein kinase, AGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284839)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005095 GTPase inhibitor activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0034973 Sid2-Mob1 complex", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000281 mitotic cytokinesis;GO:0007096 regulation of exit from mitosis;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54P47-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PC2-1", "uniprot_id": [ { "id": "GSH1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PC2", "type": "external" } ], "mass": 71956.0, "length": 626, "protein_name": "Glutamate--cysteine ligase", "gene_name": "gcsA", "organism": "Cellular slime mold", "refseq_name": "gamma glutamylcysteine synthetase", "refseq_ac": [ { "id": "XP_638453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638453", "type": "external" } ], "gene_names_uniprotkb": "gcsA; DDB_G0284651; gshA", "gene_names_refseq": "gcsA", "protein_names_uniprotkb": "Glutamate--cysteine ligase; 6.3.2.2; GCS; Gamma-ECS; Gamma-glutamylcysteine synthetase", "protein_names_refseq": "gamma glutamylcysteine synthetase; glutamate-cysteine ligase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284651)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;15993406", "class_list": "", "function": "An essential enzyme in glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) biosynthesis, GSH is essential for growth and differentiation to prespore stage (PubMed:15993406). Catalyzes the condensation of glutamate to cysteine (PubMed:15993406)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.3.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004357 glutamate-cysteine ligase activity", "go_cellular_component": "", "go_biological_process": "GO:0006750 glutathione biosynthetic process;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0007346 regulation of mitotic cell cycle;GO:0046686 response to cadmium ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54PC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PF3-1", "uniprot_id": [ { "id": "CSN5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PF3", "type": "external" } ], "mass": 37889.0, "length": 332, "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "csn5", "organism": "Cellular slime mold", "refseq_name": "COP9 signalosome complex subunit 5", "refseq_ac": [ { "id": "XP_638491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638491", "type": "external" } ], "gene_names_uniprotkb": "csn5; DDB_G0284597", "gene_names_refseq": "CSN5", "protein_names_uniprotkb": "COP9 signalosome complex subunit 5; 3.4.-.-; Signalosome subunit 5", "protein_names_refseq": "COP9 signalosome complex subunit 5; Mov34/MPN/PAD-1 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284597); (R-DDI-5696394); (R-DDI-6781823); (R-DDI-8856825); (R-DDI-8951664)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15875012;16781008", "class_list": "", "function": "Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligasew complexes, leading to modify the Ubl ligase activity. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. Csn5 is essential for growth or survival., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2PQ74", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0019784 deNEDDylase activity;GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0006508 proteolysis;GO:0051726 regulation of cell cycle;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54PF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PK9-1", "uniprot_id": [ { "id": "PDPKB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PK9", "type": "external" } ], "mass": 102361.0, "length": 908, "protein_name": "3-phosphoinositide-dependent protein kinase B", "gene_name": "pdkB", "organism": "Cellular slime mold", "refseq_name": "PDK1 family protein kinase", "refseq_ac": [ { "id": "XP_638523", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638523", "type": "external" } ], "gene_names_uniprotkb": "pdkB; DDB_G0284489", "gene_names_refseq": "pdkB", "protein_names_uniprotkb": "3-phosphoinositide-dependent protein kinase B; 2.7.11.1; Pdk-class protein kinase b", "protein_names_refseq": "PDK1 family protein kinase; protein kinase, AGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284489)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16596165", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030295 protein kinase activator activity;GO:0004676 3-phosphoinositide-dependent protein kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0030587 sorocarp development;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54PK9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PN5-1", "uniprot_id": [ { "id": "XPF_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PN5", "type": "external" } ], "mass": 110646.0, "length": 964, "protein_name": "DNA repair endonuclease XPF", "gene_name": "ercc4", "organism": "Cellular slime mold", "refseq_name": "DNA excision repair protein 4", "refseq_ac": [ { "id": "XP_638619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638619", "type": "external" } ], "gene_names_uniprotkb": "ercc4; DDB_G0284419", "gene_names_refseq": "ercc4", "protein_names_uniprotkb": "DNA repair endonuclease XPF; 3.1.-.-; DNA excision repair protein ERCC-4", "protein_names_refseq": "DNA excision repair protein 4", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284419); (R-DDI-5685938); (R-DDI-5696395); (R-DDI-6782135)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0004519 endonuclease activity;GO:0003697 single-stranded DNA binding;GO:0000014 single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "GO:0000110 nucleotide-excision repair factor 1 complex", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination;GO:0006289 nucleotide-excision repair;GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54PN5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PQ4-1", "uniprot_id": [ { "id": "GEFA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PQ4", "type": "external" } ], "mass": 70793.0, "length": 605, "protein_name": "Ras guanine nucleotide exchange factor A", "gene_name": "gefA", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor", "refseq_ac": [ { "id": "XP_638600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638600", "type": "external" } ], "gene_names_uniprotkb": "gefA; DDB_G0284329; aleA; rasGEFA", "gene_names_refseq": "gefA", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor A; Aimless; RasGEF domain-containing protein A", "protein_names_refseq": "Ras guanine nucleotide exchange factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284329); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 8, "publication_id_list": "10473630;11422293;15875012;16086850;16234315;17380187;20493808;8793298", "class_list": "", "function": "Ras-bound GDP/GTP exchange factor required for normal activation of adenylyl cyclase (PubMed:17380187). Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:16234315, PubMed:20493808, PubMed:8793298). The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q23867;Q8IS22", "ec_number_list": [], "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0004860 protein kinase inhibitor activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0030250 guanylate cyclase activator activity;GO:0010856 adenylate cyclase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:1905742 Ras guanyl-nucleotide exchange factor complex", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0010628 positive regulation of gene expression;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0000165 MAPK cascade;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q54PQ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PR9-1", "uniprot_id": [ { "id": "CF60_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PR9", "type": "external" } ], "mass": 46755.0, "length": 416, "protein_name": "Counting factor 60", "gene_name": "cf60", "organism": "Cellular slime mold", "refseq_name": "component of the counting factor complex", "refseq_ac": [ { "id": "XP_638585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638585", "type": "external" } ], "gene_names_uniprotkb": "cf60; DDB_G0284363", "gene_names_refseq": "cf60", "protein_names_uniprotkb": "Counting factor 60", "protein_names_refseq": "component of the counting factor complex; histidine acid phosphatase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284363); (R-DDI-1483166); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;16963635", "class_list": "", "function": "Cell-counting factor that limits the maximum size of the multicellular structure. Does not possess acid phosphatase activity. Cells with decreased levels of this protein form large groups while cells overexpressing this protein form small groups., [UniProtKB, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q3YBY3", "ec_number_list": [], "go_molecular_function": "GO:0016791 phosphatase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0031158 negative regulation of aggregate size involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54PR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PT2-1", "uniprot_id": [ { "id": "VPS4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PT2", "type": "external" } ], "mass": 49605.0, "length": 444, "protein_name": "Vacuolar protein sorting-associated protein 4", "gene_name": "vps4", "organism": "Cellular slime mold", "refseq_name": "AAA ATPase domain-containing protein", "refseq_ac": [ { "id": "XP_638572", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638572", "type": "external" } ], "gene_names_uniprotkb": "vps4; DDB_G0284347", "gene_names_refseq": "vps4", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 4; 3.6.4.6", "protein_names_refseq": "AAA ATPase domain-containing protein; MIT domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284347); (R-DDI-917729); (R-DDI-9668328)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment. May be involved in the release of components of the bilayered coat from the endosomal membrane. The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "5.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0036019 endolysosome", "go_biological_process": "GO:0015031 protein transport;GO:0009617 response to bacterium;GO:0009611 response to wounding;GO:0016197 endosomal transport;GO:0007033 vacuole organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54PT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PT9-1", "uniprot_id": [ { "id": "MRFA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PT9", "type": "external" } ], "mass": 104316.0, "length": 932, "protein_name": "Myelin gene regulatory factor-like A", "gene_name": "mrfA", "organism": "Cellular slime mold", "refseq_name": "NDT80/PhoG-like protein", "refseq_ac": [ { "id": "XP_638706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638706", "type": "external" } ], "gene_names_uniprotkb": "mrfA; DDB_G0284183; rcdK", "gene_names_refseq": "rcdK", "protein_names_uniprotkb": "Myelin gene regulatory factor-like A", "protein_names_refseq": "NDT80/PhoG-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284183)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12796308;15875012;22811266", "class_list": "", "function": "Transcription factor which acts as a key regulator of pstA (prestalk-A) cells differentiation. Essential for ecmA-specific gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q94474", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0016540 protein autoprocessing;GO:0031285 regulation of sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54PT9-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54PY7-1", "uniprot_id": [ { "id": "M2OM_DICDI", "url": "https://www.uniprot.org/uniprot/Q54PY7", "type": "external" } ], "mass": 35203.0, "length": 318, "protein_name": "Probable mitochondrial 2-oxoglutarate/malate carrier protein", "gene_name": "ucpC", "organism": "Cellular slime mold", "refseq_name": "mitochondrial 2-oxoglutarate/malate carrier protein", "refseq_ac": [ { "id": "XP_638658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638658", "type": "external" } ], "gene_names_uniprotkb": "ucpC; DDB_G0284225; slc25a11", "gene_names_refseq": "ucpC", "protein_names_uniprotkb": "Probable mitochondrial 2-oxoglutarate/malate carrier protein; Mitochondrial substrate carrier family protein ucpC; OGCP; Solute carrier family 25 member 11 homolog", "protein_names_refseq": "mitochondrial 2-oxoglutarate/malate carrier protein; mitochondrial brown fat uncoupling family protein; mitochondrial substrate carrier family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284225); (R-DDI-1614517); (R-DDI-428643)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;17442478", "class_list": "", "function": "Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. Does not transport glutathione. Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, gluconeogenesis from lactate, and nitrogen metabolism., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005310 dicarboxylic acid transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:0015117 thiosulfate transmembrane transporter activity;GO:0015131 oxaloacetate transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1902358 sulfate transmembrane transport;GO:0006835 dicarboxylic acid transport;GO:0015709 thiosulfate transport;GO:0015729 oxaloacetate transport;GO:0035435 phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54PY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Q04-1", "uniprot_id": [ { "id": "KYNU_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Q04", "type": "external" } ], "mass": 50799.0, "length": 451, "protein_name": "Kynureninase", "gene_name": "kynu", "organism": "Cellular slime mold", "refseq_name": "L-kynurenine hydrolase", "refseq_ac": [ { "id": "XP_638641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638641", "type": "external" } ], "gene_names_uniprotkb": "kynu; DDB_G0284203", "gene_names_refseq": "kynu", "protein_names_uniprotkb": "Kynureninase; 3.7.1.3; L-kynurenine hydrolase", "protein_names_refseq": "L-kynurenine hydrolase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284203); (R-DDI-71240)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.7.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.7.1.3", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0030429 kynureninase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0097053 L-kynurenine catabolic process;GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0019805 quinolinate biosynthetic process;GO:0043420 anthranilate metabolic process;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Q04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Q69-1", "uniprot_id": [ { "id": "DHKG_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Q69", "type": "external" } ], "mass": 383457.0, "length": 3432, "protein_name": "Hybrid signal transduction histidine kinase G", "gene_name": "dhkG", "organism": "Cellular slime mold", "refseq_name": "HisK family protein kinase", "refseq_ac": [ { "id": "XP_638728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638728", "type": "external" } ], "gene_names_uniprotkb": "dhkG; DDB_G0284045", "gene_names_refseq": "dhkG", "protein_names_uniprotkb": "Hybrid signal transduction histidine kinase G", "protein_names_refseq": "HisK family protein kinase; histidine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284045)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q95PH9", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0000155 phosphorelay sensor kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Q69-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Q71-1", "uniprot_id": [ { "id": "RIR1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Q71", "type": "external" } ], "mass": 98019.0, "length": 870, "protein_name": "Ribonucleoside-diphosphate reductase large subunit", "gene_name": "rnrA", "organism": "Cellular slime mold", "refseq_name": "ribonucleoside-diphosphate reductase", "refseq_ac": [ { "id": "XP_638726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638726", "type": "external" } ], "gene_names_uniprotkb": "rnrA; DDB_G0284071", "gene_names_refseq": "rnrA", "protein_names_uniprotkb": "Ribonucleoside-diphosphate reductase large subunit; 1.17.4.1; Ribonucleotide reductase large subunit", "protein_names_refseq": "ribonucleoside-diphosphate reductase; ribonucleotide reductase large subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284071)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.17.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.4.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor", "go_cellular_component": "GO:0005971 ribonucleoside-diphosphate reductase complex", "go_biological_process": "GO:0009263 deoxyribonucleotide biosynthetic process;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Q71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Q99-1", "uniprot_id": [ { "id": "PH2AB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Q99", "type": "external" } ], "mass": 55205.0, "length": 483, "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit phr2AB", "gene_name": "phr2aB", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase 2A B55 regulatory subunit", "refseq_ac": [ { "id": "XP_638845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638845", "type": "external" } ], "gene_names_uniprotkb": "phr2aB; DDB_G0283905; pppD", "gene_names_refseq": "phr2AB", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A regulatory subunit phr2AB; Protein phosphatase 2A 55 kDa regulatory subunit; Protein phosphatase 2A B55 regulatory subunit; Protein phosphatase 2A PR55 regulatory subunit; Protein phosphatase 2A regulatory B subunit", "protein_names_refseq": "protein phosphatase 2A B55 regulatory subunit; protein phosphatase 2A regulatory subunit; serine/threonine-protein phosphatase 2A regulatory subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283905); (R-DDI-69231); (R-DDI-69273)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;18673380", "class_list": "", "function": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017020 myosin phosphatase regulator activity;GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:0031034 myosin filament assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54Q99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QB1-1", "uniprot_id": [ { "id": "ERK2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QB1", "type": "external" } ], "mass": 41978.0, "length": 369, "protein_name": "Extracellular signal-regulated kinase 2", "gene_name": "erkB", "organism": "Cellular slime mold", "refseq_name": "ERK subfamily protein kinase", "refseq_ac": [ { "id": "XP_638833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638833", "type": "external" } ], "gene_names_uniprotkb": "erkB; DDB_G0283903; dagC; erk2", "gene_names_refseq": "erkB", "protein_names_uniprotkb": "Extracellular signal-regulated kinase 2; 2.7.11.24; Defective in aggregation protein C; ERK2; MAP kinase 2", "protein_names_refseq": "ERK subfamily protein kinase; MAP kinase; MAPK family protein kinase; extracellular response kinase; mitogen-activated protein kinase; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283903)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15875012;18408056;7844154;9427685", "class_list": "", "function": "Implicated in the relay of the cAMP chemotactic signal and cell differentiation. Important for receptor-mediated activation of adenylyl cyclase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7M445", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0031267 small GTPase binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0010628 positive regulation of gene expression;GO:0032496 response to lipopolysaccharide;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54QB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QC8-1", "uniprot_id": [ { "id": "SEC1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QC8", "type": "external" } ], "mass": 67773.0, "length": 598, "protein_name": "Protein transport protein sec1", "gene_name": "sec1", "organism": "Cellular slime mold", "refseq_name": "Sec1-like family protein", "refseq_ac": [ { "id": "XP_638816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638816", "type": "external" } ], "gene_names_uniprotkb": "sec1; DDB_G0283937; sec1A", "gene_names_refseq": "sec1", "protein_names_uniprotkb": "Protein transport protein sec1", "protein_names_refseq": "Sec1-like family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283937); (R-DDI-114516); (R-DDI-114608); (R-DDI-449836)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "15875012;17684569", "class_list": "", "function": "Involved in docking and fusion of exocytic vesicles., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030141 secretory granule", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007009 plasma membrane organization;GO:0016192 vesicle-mediated transport;GO:0048870 cell motility;GO:0071470 cellular response to osmotic stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54QC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QE4-1", "uniprot_id": [ { "id": "PURCE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QE4", "type": "external" } ], "mass": 108939.0, "length": 997, "protein_name": "Bifunctional purine synthesis protein purC/E", "gene_name": "E", "organism": "Cellular slime mold", "refseq_name": "phosphoribosylaminoimidazole carboxylase", "refseq_ac": [ { "id": "XP_638800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638800", "type": "external" } ], "gene_names_uniprotkb": "E; DDB_G0283987; purC; purE", "gene_names_refseq": "purC/E", "protein_names_uniprotkb": "Bifunctional purine synthesis protein purC/E; AIR carboxylase; AIRC; SAICAR synthetase", "protein_names_refseq": "phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283987)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Bifunctional enzyme involved in de novo IMP synthesis, an essential step for de nove purine synthesis., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.21", "type": "external" }, { "id": "6.3.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.6", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity;GO:0004638 phosphoribosylaminoimidazole carboxylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006144 purine nucleobase metabolic process;GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QE4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QE6-1", "uniprot_id": [ { "id": "SIR2A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QE6", "type": "external" } ], "mass": 57413.0, "length": 512, "protein_name": "NAD-dependent deacetylase sir2A", "gene_name": "sir2A", "organism": "Cellular slime mold", "refseq_name": "NAD(+)-dependent deacetylase, silent information regulator protein family protein", "refseq_ac": [ { "id": "XP_638798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638798", "type": "external" } ], "gene_names_uniprotkb": "sir2A; DDB_G0283917", "gene_names_refseq": "sir2A", "protein_names_uniprotkb": "NAD-dependent deacetylase sir2A; 2.3.1.286; Silent information regulator sir2A", "protein_names_refseq": "NAD(+)-dependent deacetylase, silent information regulator protein family protein; UBP-type zinc finger-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283917)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "NAD-dependent deacetylase, which plays an important role in the regulation of transcriptional repression., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070403 NAD+ binding;GO:0017136 histone deacetylase activity, NAD-dependent", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0000183 rDNA heterochromatin formation;GO:0061909 autophagosome-lysosome fusion;GO:0031149 sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QG0-1", "uniprot_id": [ { "id": "PGFB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QG0", "type": "external" } ], "mass": 89838.0, "length": 769, "protein_name": "Bifunctional glycosyltransferase pgtA", "gene_name": "pgtA", "organism": "Cellular slime mold", "refseq_name": "GlcNAc transferase", "refseq_ac": [ { "id": "XP_638911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638911", "type": "external" } ], "gene_names_uniprotkb": "pgtA; DDB_G0283761; fucB", "gene_names_refseq": "pgtA", "protein_names_uniprotkb": "Bifunctional glycosyltransferase pgtA; FT85", "protein_names_refseq": "GlcNAc transferase; N-acetylgalactosamine 3-beta-galactosyltransferase; bifunctional glycosyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283761)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11423539;12244067;15875012", "class_list": "glycogene;glycosyltransferase", "function": "Bifunctional protein composed of 2 glycosyltransferase domains involved in glycosylating skp1. The N-terminal part catalyzes the transfer of a galactose residue to GlcNAc-skp1 in a beta 1-3 linkage. The C-terminal part catalyzes the transfer of a fucose residue to Gal-GlcNAc-skp1 in an alpha 1-2 linkage., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9NAX6", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.69", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.69", "type": "external" } ], "go_molecular_function": "GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity;GO:0008417 fucosyltransferase activity;GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity;GO:0031127 alpha-(1,2)-fucosyltransferase activity;GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0010265 SCF complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54QG0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QG9-1", "uniprot_id": [ { "id": "UBA3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QG9", "type": "external" } ], "mass": 49301.0, "length": 442, "protein_name": "NEDD8-activating enzyme E1 catalytic subunit", "gene_name": "uba3", "organism": "Cellular slime mold", "refseq_name": "NEDD8-activating enzyme E1 catalytic subunit", "refseq_ac": [ { "id": "XP_638902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638902", "type": "external" } ], "gene_names_uniprotkb": "uba3; DDB_G0283891; ube1c", "gene_names_refseq": "ube1c", "protein_names_uniprotkb": "NEDD8-activating enzyme E1 catalytic subunit; 6.2.1.64; NEDD8-activating enzyme E1C; Ubiquitin-activating enzyme 3; Ubiquitin-activating enzyme E1C; Ubiquitin-like modifier-activating enzyme 3", "protein_names_refseq": "NEDD8-activating enzyme E1 catalytic subunit; ubiquitin-activating enzyme 3; ubiquitin-activating enzyme E1C", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283891); (R-DDI-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Regulatory subunit of the dimeric uba3-nae1 E1 enzyme. E1 activates nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a nedd8-uba3 thioester and free AMP. E1 finally transfers nedd8 to the catalytic cysteine of ube2m (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "6.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019781 NEDD8 activating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QI2-1", "uniprot_id": [ { "id": "Y9877_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QI2", "type": "external" } ], "mass": 103673.0, "length": 941, "protein_name": "Serine/threonine-protein kinase DDB_G0283821", "gene_name": "DDB_G0283821", "organism": "Cellular slime mold", "refseq_name": "protein kinase, STE group", "refseq_ac": [ { "id": "XP_638889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638889", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0283821", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase DDB_G0283821; 2.7.11.1", "protein_names_refseq": "protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283821)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17659086", "class_list": "", "function": "May play a role in responding to changes in cAMP levels., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54QI2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QJ9-1", "uniprot_id": [ { "id": "KAD2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QJ9", "type": "external" } ], "mass": 30985.0, "length": 276, "protein_name": "Adenylate kinase", "gene_name": "adkA", "organism": "Cellular slime mold", "refseq_name": "adenylate kinase", "refseq_ac": [ { "id": "XP_638872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638872", "type": "external" } ], "gene_names_uniprotkb": "adkA; DDB_G0283805", "gene_names_refseq": "adkA", "protein_names_uniprotkb": "Adenylate kinase; 2.7.4.3; ATP-AMP transphosphorylase; ATP:AMP phosphotransferase; Adenylate kinase A; Adenylate kinase cytosolic and mitochondrial; Adenylate monophosphate kinase", "protein_names_refseq": "adenylate kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283805); (R-DDI-499943)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" } ], "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005829 cytosol", "go_biological_process": "GO:0006172 ADP biosynthetic process;GO:0046033 AMP metabolic process;GO:0006166 purine ribonucleoside salvage;GO:0046034 ATP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QM4-1", "uniprot_id": [ { "id": "DNLI3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QM4", "type": "external" } ], "mass": 132048.0, "length": 1175, "protein_name": "DNA ligase 3", "gene_name": "lig3", "organism": "Cellular slime mold", "refseq_name": "BRCT domain-containing protein", "refseq_ac": [ { "id": "XP_638847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638847", "type": "external" } ], "gene_names_uniprotkb": "lig3; DDB_G0283857", "gene_names_refseq": "lig3", "protein_names_uniprotkb": "DNA ligase 3; 6.5.1.1; DNA ligase III; Polydeoxyribonucleotide synthase [ATP] 3", "protein_names_refseq": "BRCT domain-containing protein; DNA ligase III", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283857); (R-DDI-110381); (R-DDI-5649702)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "The alpha isoform interacts with DNA-repair protein XRCC1 and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. The beta isoform does not interact with XRCC1 and may be specifically involved in the completion of homologous recombination events that occur during meiotic prophase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006273 lagging strand elongation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QM4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QM5-1", "uniprot_id": [ { "id": "GPHR_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QM5", "type": "external" } ], "mass": 64245.0, "length": 547, "protein_name": "Golgi pH regulator homolog", "gene_name": "gpr89", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_638846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638846", "type": "external" } ], "gene_names_uniprotkb": "gpr89; DDB_G0283855; gphr", "gene_names_refseq": "", "protein_names_uniprotkb": "Golgi pH regulator homolog; Protein GPR89", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283855)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009306 protein secretion;GO:0010468 regulation of gene expression;GO:0048870 cell motility;GO:0048388 endosomal lumen acidification;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QM6-1", "uniprot_id": [ { "id": "MPIP_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QM6", "type": "external" } ], "mass": 117119.0, "length": 1053, "protein_name": "M-phase inducer phosphatase", "gene_name": "cdc25", "organism": "Cellular slime mold", "refseq_name": "rhodanese-like domain-containing protein", "refseq_ac": [ { "id": "XP_638997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638997", "type": "external" } ], "gene_names_uniprotkb": "cdc25; DDB_G0283617", "gene_names_refseq": "cdc25", "protein_names_uniprotkb": "M-phase inducer phosphatase; 3.1.3.48; Dual specificity phosphatase cdc25", "protein_names_refseq": "rhodanese-like domain-containing protein; tyrosine phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283617); (R-DDI-156711); (R-DDI-176187); (R-DDI-5625740); (R-DDI-5689880); (R-DDI-6804115); (R-DDI-69200); (R-DDI-69202); (R-DDI-69273); (R-DDI-69601); (R-DDI-69656); (R-DDI-75035)", "pathway_count": 12, "publication_count": 2, "publication_id_list": "15351882;15875012", "class_list": "", "function": "Tyrosine protein phosphatase which may function as a dosage-dependent inducer in mitotic control., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q86M49", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0110032 positive regulation of G2/MI transition of meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54QM6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QQ0-1", "uniprot_id": [ { "id": "IMDH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QQ0", "type": "external" } ], "mass": 56311.0, "length": 515, "protein_name": "Inosine-5'-monophosphate dehydrogenase", "gene_name": "impdh", "organism": "Cellular slime mold", "refseq_name": "IMP dehydrogenase", "refseq_ac": [ { "id": "XP_638973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638973", "type": "external" } ], "gene_names_uniprotkb": "impdh; DDB_G0283701; guaB", "gene_names_refseq": "guaB", "protein_names_uniprotkb": "Inosine-5'-monophosphate dehydrogenase; 1.1.1.205; IMP dehydrogenase; IMPDH; IMPD", "protein_names_refseq": "IMP dehydrogenase; inosine-5'-monophosphate dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283701); (R-DDI-6798695); (R-DDI-73817); (R-DDI-9748787)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "15875012;16469056", "class_list": "", "function": "Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and 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dehydrogenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006177 GMP biosynthetic process;GO:0006183 GTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54QQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QQ1-1", "uniprot_id": [ { "id": "PHG2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QQ1", "type": "external" } ], "mass": 154449.0, "length": 1387, "protein_name": "Serine/threonine-protein kinase phg2", "gene_name": "phg2", "organism": "Cellular slime mold", "refseq_name": "ARK family protein kinase", "refseq_ac": [ { "id": "XP_638972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638972", "type": "external" } ], "gene_names_uniprotkb": "phg2; DDB_G0283699", "gene_names_refseq": "phg2", "protein_names_uniprotkb": "Serine/threonine-protein kinase phg2; 2.7.11.1", "protein_names_refseq": "ARK family protein kinase; protein kinase, TKL group; protein serine/threonine kinase; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283699); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 6, "publication_id_list": "15194808;15875012;16325504;16769729;16987957;17371831", "class_list": "", "function": "Serine/threonine kinase regulating cell substrate adhesion, phagocytosis, motility, chemotaxis, and actin cytoskeleton organization. It is a downstream component of Rap1-regulated adhesion, and it is a regulator of myosin II phosphorylation. 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The proteasome has an ATP-dependent proteolytic activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54QR2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QR9-1", "uniprot_id": [ { "id": "2AAA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QR9", "type": "external" } ], "mass": 65076.0, "length": 584, "protein_name": "Protein phosphatase 2A scaffold subunit", "gene_name": "pppA", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase 2A scaffold subunit", "refseq_ac": [ { "id": "XP_638954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638954", "type": "external" } ], "gene_names_uniprotkb": "pppA; DDB_G0283601; rcdB; veg124", "gene_names_refseq": "pppA", "protein_names_uniprotkb": "Protein phosphatase 2A scaffold subunit; Protein phosphatase 2A 65 kDa regulatory subunit; Protein phosphatase 2A A subunit; Serine/threonine-protein phosphatase 2A regulatory subunit pppA", "protein_names_refseq": "protein phosphatase 2A scaffold subunit; protein phosphatase 2A subunit A", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283601); (R-DDI-113501); (R-DDI-198753); (R-DDI-202670); (R-DDI-389513); (R-DDI-5675221); (R-DDI-6811558); (R-DDI-69231); (R-DDI-69273); (R-DDI-9833482)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "15875012;18673380;20493808", "class_list": "", "function": "Scaffolding molecule which may coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (PubMed:20493808). Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808). The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q23922", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0019888 protein phosphatase regulator activity;GO:0017018 myosin phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0000159 protein phosphatase type 2A complex;GO:1905742 Ras guanyl-nucleotide exchange factor complex", "go_biological_process": "GO:0031034 myosin filament assembly;GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0051225 spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54QR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QT7-1", "uniprot_id": [ { "id": "CBPC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QT7", "type": "external" } ], "mass": 19086.0, "length": 166, "protein_name": "Calcium-binding protein C", "gene_name": "cbpC", "organism": "Cellular slime mold", "refseq_name": "calcium-binding protein", "refseq_ac": [ { "id": "XP_638936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638936", "type": "external" } ], "gene_names_uniprotkb": "cbpC; DDB_G0283613; cbp3", "gene_names_refseq": "cbpC", "protein_names_uniprotkb": "Calcium-binding protein C; Calcium-binding protein 3", "protein_names_refseq": "calcium-binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283613)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15843041;15875012;9883904", "class_list": "", "function": "Plays a role during cell aggregation and slug migration., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O97112", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005938 cell cortex", "go_biological_process": "GO:0040011 locomotion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54QT7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54QV3-1", "uniprot_id": [ { "id": "YAKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54QV3", "type": "external" } ], "mass": 166973.0, "length": 1458, "protein_name": "Probable serine/threonine-protein kinase yakA", "gene_name": "yakA", "organism": "Cellular slime mold", "refseq_name": "DYRK family protein kinase", "refseq_ac": [ { "id": "XP_638920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638920", "type": "external" } ], "gene_names_uniprotkb": "yakA; DDB_G0283605; dagB", "gene_names_refseq": "yakA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase yakA; 2.7.12.1", "protein_names_refseq": "DYRK family protein kinase; protein kinase, CMGC group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283605); (R-DDI-3899300)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10375515;11410593;12134067;15875012;9584128", "class_list": "", "function": "General sensor of environmental conditions, such as heat stress, effecting changes through pkaC. Essential for survival to nitrosoative and oxidative stresses. Required for cell cycle control, not only at the onset but also during development (aggregation process and postaggregative development)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:1904643 response to curcumin;GO:0006935 chemotaxis;GO:0006979 response to oxidative stress;GO:0007165 signal transduction;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54QV3-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54R41-1", "uniprot_id": [ { "id": "GPA9_DICDI", "url": "https://www.uniprot.org/uniprot/Q54R41", "type": "external" } ], "mass": 39660.0, "length": 342, "protein_name": "Guanine nucleotide-binding protein alpha-9 subunit", "gene_name": "gpaI", "organism": "Cellular slime mold", "refseq_name": "G-protein subunit alpha 9", "refseq_ac": [ { "id": "XP_639050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639050", "type": "external" } ], "gene_names_uniprotkb": "gpaI; DDB_G0283419; gpa9", "gene_names_refseq": "gpaI", "protein_names_uniprotkb": "Guanine nucleotide-binding protein alpha-9 subunit; G alpha-9", "protein_names_refseq": "G-protein subunit alpha 9", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283419); (R-DDI-170660); (R-DDI-170670); (R-DDI-418594); (R-DDI-418597)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "12176329;15059962;15875012", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-9 antagonizes broad chemotactic response. It functions rapidly following receptor stimulation to negatively regulate PI3K/PTEN, adenylyl cyclase, and guanylyl cyclase pathways., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0030308 negative regulation of cell growth;GO:1903077 negative regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54R41-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54R74-1", "uniprot_id": [ { "id": "WASC4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54R74", "type": "external" } ], "mass": 131571.0, "length": 1135, "protein_name": "WASH complex subunit 4", "gene_name": "washc4", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_639109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639109", "type": "external" } ], "gene_names_uniprotkb": "washc4; DDB_G0283355", "gene_names_refseq": "", "protein_names_uniprotkb": "WASH complex subunit 4; WASH complex subunit SWIP homolog", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283355)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0071203 WASH complex;GO:0061474 phagolysosome membrane", "go_biological_process": "GO:0007032 endosome organization;GO:0016197 endosomal transport;GO:0030041 actin filament polymerization;GO:0006887 exocytosis;GO:0061462 protein localization to lysosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54R74-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54R82-1", "uniprot_id": [ { "id": "MKKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54R82", "type": "external" } ], "mass": 105796.0, "length": 942, "protein_name": "Mitogen-activated protein kinase kinase kinase A", "gene_name": "mkkA", "organism": "Cellular slime mold", "refseq_name": "F-box-containing protein", "refseq_ac": [ { "id": "XP_639165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639165", "type": "external" } ], "gene_names_uniprotkb": "mkkA; DDB_G0283265", "gene_names_refseq": "mkkA", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase A; 2.7.11.25; MAPK/ERK kinase 1; MAPK/ERK kinase A; MEK kinase 1; MEK kinase A; MEKK 1; MEKK A; MEKKalpha", "protein_names_refseq": "F-box-containing protein; MEK kinase; STE11 family protein kinase; WD40 repeat-containing protein; octicosapeptide/Phox/Bem1p domain-containing protein; protein kinase, STE group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283265)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;9832508", "class_list": "", "function": "Regulates cell-type differentiation and spatial patterning, required for the proper induction and maintenance of prespore cell differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O96611", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004709 MAP kinase kinase kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0016020 membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0009653 anatomical structure morphogenesis;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54R82-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RB7-1", "uniprot_id": [ { "id": "SHKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RB7", "type": "external" } ], "mass": 59447.0, "length": 527, "protein_name": "Dual specificity protein kinase shkA", "gene_name": "shkA", "organism": "Cellular slime mold", "refseq_name": "SH2 domain-containing protein", "refseq_ac": [ { "id": "XP_639130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639130", "type": "external" } ], "gene_names_uniprotkb": "shkA; DDB_G0283267; shk1", "gene_names_refseq": "shkA", "protein_names_uniprotkb": "Dual specificity protein kinase shkA; 2.7.11.1; SH2 domain-containing protein 1; SH2 domain-containing protein A", "protein_names_refseq": "SH2 domain-containing protein; SHK subfamily protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283267)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11274054;15875012", "class_list": "", "function": "Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells. Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway. Predominantly phosphorylates serines and threonines and tyrosines at a lower level., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9BI25", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0016020 membrane", "go_biological_process": "GO:0006935 chemotaxis;GO:0007165 signal transduction;GO:0006909 phagocytosis;GO:0030036 actin cytoskeleton organization;GO:0009968 negative regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54RB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RD4-1", "uniprot_id": [ { "id": "DPOE1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RD4", "type": "external" } ], "mass": 275442.0, "length": 2380, "protein_name": "DNA polymerase epsilon catalytic subunit A", "gene_name": "pole", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_639211", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639211", "type": "external" } ], "gene_names_uniprotkb": "pole; DDB_G0283189; pol2", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA polymerase epsilon catalytic subunit A; 2.7.7.7; DNA polymerase II subunit A", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283189); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-68952); (R-DDI-68962)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "DNA polymerase II participates in chromosomal DNA replication., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0008622 epsilon DNA polymerase complex;GO:0005657 replication fork", "go_biological_process": "GO:0006272 leading strand elongation;GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006287 base-excision repair, gap-filling;GO:0045004 DNA replication proofreading;GO:0000278 mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54RD4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RD6-1", "uniprot_id": [ { "id": "PP2AB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RD6", "type": "external" } ], "mass": 35694.0, "length": 312, "protein_name": "Protein phosphatase 2A catalytic subunit B", "gene_name": "pho2B", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase", "refseq_ac": [ { "id": "XP_639209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639209", "type": "external" } ], "gene_names_uniprotkb": "pho2B; DDB_G0283187", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein phosphatase 2A catalytic subunit B; 3.1.3.16; PP2A-C2", "protein_names_refseq": "protein phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283187)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;20493808", "class_list": "", "function": "Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808). The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0090443 FAR/SIN/STRIPAK complex;GO:1905742 Ras guanyl-nucleotide exchange factor complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54RD6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RF4-1", "uniprot_id": [ { "id": "CBP4A_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RF4", "type": "external" } ], "mass": 18704.0, "length": 162, "protein_name": "Calcium-binding protein 4a", "gene_name": "cbpD1", "organism": "Cellular slime mold", "refseq_name": "calcium-binding protein", "refseq_ac": [ { "id": "XP_639191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639191", "type": "external" } ], "gene_names_uniprotkb": "cbpD1; DDB_G0283153", "gene_names_refseq": "cbpD1", "protein_names_uniprotkb": "Calcium-binding protein 4a", "protein_names_refseq": "calcium-binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283153)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10771103;11923193;12912885;15325281;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GYE0", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54RF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RP0-1", "uniprot_id": [ { "id": "AGTA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RP0", "type": "external" } ], "mass": 75244.0, "length": 648, "protein_name": "UDP-galactose:fucoside alpha-3-galactosyltransferase", "gene_name": "agtA", "organism": "Cellular slime mold", "refseq_name": "UDP-Gal:fucoside alpha3-galactosyltransferase", "refseq_ac": [ { "id": "XP_639311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639311", "type": "external" } ], "gene_names_uniprotkb": "agtA; DDB_G0283005; GT78", "gene_names_refseq": "agtA", "protein_names_uniprotkb": "UDP-galactose:fucoside alpha-3-galactosyltransferase; 2.4.1.37; Alpha-GalT1; Fucosylgalactoside 3-alpha-galactosyltransferase; Skp1 alpha-3-galactosyltransferase", "protein_names_refseq": "UDP-Gal:fucoside alpha3-galactosyltransferase; WD40 repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283005); (R-DDI-69601); (R-DDI-8951664); (R-DDI-983168)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "15123660;15875012;16495217", "class_list": "glycogene;glycosyltransferase", "function": "Specifically catalyzes the transfer of a galactosyl residue to the hydroxyproline-linked saccharide on Skp1 protein (fpaA/fpaB). Catalyzes the formation of a Gal-alpha-1,3-Fuc linkage, leading to Gal-Fuc-Gal-GlcNAc-HyPro143-Skp1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2LAG6", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0004381 fucosylgalactoside 3-alpha-galactosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0043687 post-translational protein modification;GO:0010265 SCF complex assembly;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54RP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RQ1-1", "uniprot_id": [ { "id": "SODC3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RQ1", "type": "external" } ], "mass": 43572.0, "length": 407, "protein_name": "Extracellular superoxide dismutase [Cu-Zn] 3", "gene_name": "sodC", "organism": "Cellular slime mold", "refseq_name": "superoxide dismutase", "refseq_ac": [ { "id": "XP_639300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639300", "type": "external" } ], "gene_names_uniprotkb": "sodC; DDB_G0282993", "gene_names_refseq": "sodC", "protein_names_uniprotkb": "Extracellular superoxide dismutase [Cu-Zn] 3; 1.15.1.1; EC-SOD 3", "protein_names_refseq": "superoxide dismutase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282993); (R-DDI-3299685)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12913271;15875012", "class_list": "", "function": "Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxyde radicals into hydrogen peroxyde and oxygen., [UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q52KB2", "ec_number_list": [ { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004784 superoxide dismutase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0006979 response to oxidative stress;GO:0032956 regulation of actin cytoskeleton organization;GO:0032880 regulation of protein localization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54RQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RR8-1", "uniprot_id": [ { "id": "RDEA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RR8", "type": "external" } ], "mass": 27893.0, "length": 254, "protein_name": "Phosphorelay intermediate protein rdeA", "gene_name": "rdeA", "organism": "Cellular slime mold", "refseq_name": "Hpt domain-containing protein", "refseq_ac": [ { "id": "XP_639283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639283", "type": "external" } ], "gene_names_uniprotkb": "rdeA; DDB_G0282923", "gene_names_refseq": "rdeA", "protein_names_uniprotkb": "Phosphorelay intermediate protein rdeA; Hpt domain-containing protein rdeA; Rapid development protein A", "protein_names_refseq": "Hpt domain-containing protein; histidine-containing phosphotransfer domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282923)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10488068;11060029;15875012;16765443;17659086;6298035;9582274;9812977", "class_list": "", "function": "Phosphorelay protein that supplies phosphate to regA or accepts phosphate from regA; depending on the relative concentration of the phosphodonor proteins. In vitro, acts as a substrate for cheA (bacterial kinase). Plays a role in the development. ypd1 (yeast) can complement rdeA defect., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O77083", "ec_number_list": [], "go_molecular_function": "GO:0043424 protein histidine kinase binding;GO:0009927 histidine phosphotransfer kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000160 phosphorelay signal transduction system;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0030587 sorocarp development;GO:0031288 sorocarp morphogenesis;GO:0061128 positive regulation of chemotaxis to cAMP by DIF-2", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q54RR8-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RT9-1", "uniprot_id": [ { "id": "FNTA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RT9", "type": "external" } ], "mass": 38207.0, "length": 322, "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "fntA", "organism": "Cellular slime mold", "refseq_name": "protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit", "refseq_ac": [ { "id": "XP_639262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639262", "type": "external" } ], "gene_names_uniprotkb": "fntA; DDB_G0283053", "gene_names_refseq": "fntA", "protein_names_uniprotkb": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; 2.5.1.58; 2.5.1.59; CAAX farnesyltransferase subunit alpha; FTase-alpha; GGTase-I-alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha", "protein_names_refseq": "protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit; protein prenyltransferase alpha subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283053); (R-DDI-9648002); (R-DDI-9953170)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.60", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.5.1.58", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.58", "type": "external" }, { "id": "2.5.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.59", "type": "external" } ], "go_molecular_function": "GO:0004660 protein farnesyltransferase activity;GO:0004661 protein geranylgeranyltransferase activity;GO:0004662 CAAX-protein geranylgeranyltransferase activity", "go_cellular_component": "GO:0005953 CAAX-protein geranylgeranyltransferase complex;GO:0005965 protein farnesyltransferase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0018343 protein farnesylation;GO:0018344 protein geranylgeranylation;GO:0007323 peptide pheromone maturation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54RT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RV9-1", "uniprot_id": [ { "id": "SGPL_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RV9", "type": "external" } ], "mass": 58239.0, "length": 528, "protein_name": "Sphingosine-1-phosphate lyase", "gene_name": "sglA", "organism": "Cellular slime mold", "refseq_name": "S1P lyase", "refseq_ac": [ { "id": "XP_639378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639378", "type": "external" } ], "gene_names_uniprotkb": "sglA; DDB_G0282819", "gene_names_refseq": "sglA", "protein_names_uniprotkb": "Sphingosine-1-phosphate lyase; 4.1.2.27; S1P lyase; S1PL; SP-lyase; SPL; Sphingosine-1-phosphate aldolase", "protein_names_refseq": "S1P lyase; sphingosine-1-phosphate lyase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282819); (R-DDI-9845614)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10974109;11566853;15190000;15476260;15875012", "class_list": "", "function": "Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine (By similarity). Sphingosine-1-phosphate (S1P) probably acts intracellularly as a second messenger perhaps by promoting cell proliferation; the absence of S1P lyase increases its concentration. This leads to increased lateral pseudopod formation as well as defects in the efficiency of chemotaxis (PubMed:15476260). Overexpression of S1P lyase causes decreased growth rates, entry into stationary phase at lower cell density and increased sensitivity to the antitumor agents cisplatin and carboplatin; these effects are more pronounced in cells that express more enzyme (PubMed:15190000)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7Z271;Q9NC67", "ec_number_list": [ { "id": "4.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.27", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0008117 sphinganine-1-phosphate aldolase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030149 sphingolipid catabolic process;GO:0006935 chemotaxis;GO:0030036 actin cytoskeleton organization;GO:0048870 cell motility;GO:0001667 ameboidal-type cell migration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54RV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S20-1", "uniprot_id": [ { "id": "MED13_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S20", "type": "external" } ], "mass": 298838.0, "length": 2678, "protein_name": "Mediator of RNA polymerase II transcription subunit 13", "gene_name": "amiB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640219", "type": "external" } ], "gene_names_uniprotkb": "amiB; DDB_G0282375; med13", "gene_names_refseq": "amiB", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 13; Aggregation minus B protein; Mediator complex subunit 13", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282375)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10651904;15259052;15875012;18515835", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for the starvation-induced activation of the ACA (adenylyl cyclase) expression pathway at the growth/differentiation transition., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9NDS4", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006935 chemotaxis;GO:0010468 regulation of gene expression;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54S20-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S31-1", "uniprot_id": [ { "id": "PEX10_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S31", "type": "external" } ], "mass": 44081.0, "length": 374, "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "pex10", "organism": "Cellular slime mold", "refseq_name": "RING zinc finger-containing protein", "refseq_ac": [ { "id": "XP_640208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640208", "type": "external" } ], "gene_names_uniprotkb": "pex10; DDB_G0282693", "gene_names_refseq": "pex10", "protein_names_uniprotkb": "Peroxisome biogenesis factor 10; 2.3.2.27; Peroxin-10; Peroxisomal biogenesis factor 10; Peroxisome assembly protein 10", "protein_names_refseq": "RING zinc finger-containing protein; peroxin 10; peroxisome biogenesis factor 10; transmembrane protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282693); (R-DDI-8866654); (R-DDI-9033241)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity). The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity). PEX10 also regulates PEX5 recycling by acting as a E3 ubiquitin-protein ligase (By similarity). When PEX5 recycling is compromised, PEX10 catalyzes polyubiquitination of PEX5 during its passage through the retrotranslocation channel, leading to its degradation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "4.2.1.119", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.119", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "1.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.4", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0007031 peroxisome organization;GO:0016567 protein ubiquitination;GO:0016558 protein import into peroxisome matrix", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54S31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S40-1", "uniprot_id": [ { "id": "GBPD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S40", "type": "external" } ], "mass": 143659.0, "length": 1312, "protein_name": "Cyclic GMP-binding protein D", "gene_name": "gbpD", "organism": "Cellular slime mold", "refseq_name": "RasGEF domain-containing protein", "refseq_ac": [ { "id": "XP_640199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640199", "type": "external" } ], "gene_names_uniprotkb": "gbpD; DDB_G0282373; gefU; rapgef", "gene_names_refseq": "gbpD", "protein_names_uniprotkb": "Cyclic GMP-binding protein D; Guanine nucleotide exchange factor for rap1; Ras guanine nucleotide exchange factor U; RasGEF domain-containing protein U", "protein_names_refseq": "RasGEF domain-containing protein; cyclic GMP-binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282373)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12011437;12198158;15827084;15875012;16086850", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP (By similarity). Induces the formation of substrate-attached pseudopodia, that leads to increased adhesion and thereby negatively influencing cell speed and polarity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MVR0", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0030553 cGMP binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:2000145 regulation of cell motility;GO:0007265 Ras protein signal transduction;GO:0050920 regulation of chemotaxis;GO:0032060 bleb assembly;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54S40-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S77-1", "uniprot_id": [ { "id": "VPS15_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S77", "type": "external" } ], "mass": 216970.0, "length": 1966, "protein_name": "Probable serine/threonine-protein kinase vps15", "gene_name": "vps15", "organism": "Cellular slime mold", "refseq_name": "VPS15 family protein kinase", "refseq_ac": [ { "id": "XP_640162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640162", "type": "external" } ], "gene_names_uniprotkb": "vps15; DDB_G0282627; pik3r4", "gene_names_refseq": "vps15", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase vps15; 2.7.11.1; Phosphoinositide 3-kinase regulatory subunit 4; Vacuolar protein sorting protein 15", "protein_names_refseq": "VPS15 family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282627); (R-DDI-1632852); (R-DDI-1660514); (R-DDI-1660516); (R-DDI-1660517); (R-DDI-5668599)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005770 late endosome;GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II", "go_biological_process": "GO:0007034 vacuolar transport;GO:0045053 protein retention in Golgi apparatus;GO:0006468 protein phosphorylation;GO:0045324 late endosome to vacuole transport;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54S77-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S83-1", "uniprot_id": [ { "id": "NDUF7_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S83", "type": "external" } ], "mass": 55025.0, "length": 484, "protein_name": "Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial", "gene_name": "midA", "organism": "Cellular slime mold", "refseq_name": "DUF185 family protein", "refseq_ac": [ { "id": "XP_640156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640156", "type": "external" } ], "gene_names_uniprotkb": "midA; DDB_G0282615", "gene_names_refseq": "midA", "protein_names_uniprotkb": "Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial; 2.1.1.320; Mitochondrial dysfunction gene A; NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 homolog", "protein_names_refseq": "DUF185 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282615); (R-DDI-6799198)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "15875012;16507593;20406883", "class_list": "", "function": "Involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:16507593, PubMed:20406883). Acts as an arginine methyltransferase and probably acts by mediating arginine methylation of ndufs2 (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "2.1.1.320", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.320", "type": "external" } ], "go_molecular_function": "GO:0035243 protein-arginine omega-N symmetric methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006536 glutamate metabolic process;GO:0005977 glycogen metabolic process;GO:0006909 phagocytosis;GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0010507 negative regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54S83-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SD0-1", "uniprot_id": [ { "id": "RABS_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SD0", "type": "external" } ], "mass": 25288.0, "length": 221, "protein_name": "Ras-related protein RabS", "gene_name": "rabS", "organism": "Cellular slime mold", "refseq_name": "Rab GTPase", "refseq_ac": [ { "id": "XP_640109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640109", "type": "external" } ], "gene_names_uniprotkb": "rabS; DDB_G0282537", "gene_names_refseq": "rabS", "protein_names_uniprotkb": "Ras-related protein RabS", "protein_names_refseq": "Rab GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282537); (R-DDI-162658); (R-DDI-204005); (R-DDI-6807878); (R-DDI-6811434); (R-DDI-6811440); (R-DDI-8873719); (R-DDI-8876198)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006970 response to osmotic stress;GO:2001135 regulation of endocytic recycling;GO:0006971 hypotonic response;GO:0090182 regulation of secretion of lysosomal enzymes", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54SD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SD5-1", "uniprot_id": [ { "id": "PEMT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SD5", "type": "external" } ], "mass": 24515.0, "length": 213, "protein_name": "Phosphatidylethanolamine N-methyltransferase A", "gene_name": "pemtA", "organism": "Cellular slime mold", "refseq_name": "phosphatidylethanolamine N-methyltransferase", "refseq_ac": [ { "id": "XP_640104", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640104", "type": "external" } ], "gene_names_uniprotkb": "pemtA; DDB_G0282527", "gene_names_refseq": "pemtA", "protein_names_uniprotkb": "Phosphatidylethanolamine N-methyltransferase A; 2.1.1.17; 2.1.1.71; PEAMT; PEMT; PLMT; Phospholipid methyltransferase A", "protein_names_refseq": "phosphatidylethanolamine N-methyltransferase; phospholipid methyltransferase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282527); (R-DDI-1483191)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.17", "type": "external" }, { "id": "2.1.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.71", "type": "external" } ], "go_molecular_function": "GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity;GO:0004608 phosphatidylethanolamine N-methyltransferase activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006656 phosphatidylcholine biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54SD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SF9-1", "uniprot_id": [ { "id": "MHCKD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SF9", "type": "external" } ], "mass": 105417.0, "length": 941, "protein_name": "Myosin heavy chain kinase D", "gene_name": "mhkD", "organism": "Cellular slime mold", "refseq_name": "Alpha kinase family protein", "refseq_ac": [ { "id": "XP_640080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640080", "type": "external" } ], "gene_names_uniprotkb": "mhkD; DDB_G0282489; mhckD", "gene_names_refseq": "mhkD", "protein_names_uniprotkb": "Myosin heavy chain kinase D; 2.7.11.7; MHCK-D", "protein_names_refseq": "Alpha kinase family protein; MHCK subfamily protein kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282489); (R-DDI-166208)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12952069;15875012;15987738", "class_list": "", "function": "Phosphorylates threonine (By similarity). Not critical for regulating the assembly and disassembly of myosin II filament., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.7", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016905 myosin heavy chain kinase activity", "go_cellular_component": "GO:0005826 actomyosin contractile ring", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0000281 mitotic cytokinesis;GO:0031037 myosin II filament disassembly;GO:1903013 response to differentiation-inducing factor 1", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54SF9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SH8-1", "uniprot_id": [ { "id": "GRLH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SH8", "type": "external" } ], "mass": 84896.0, "length": 764, "protein_name": "Metabotropic glutamate receptor-like protein H", "gene_name": "grlH", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family 3 protein 8", "refseq_ac": [ { "id": "XP_640061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640061", "type": "external" } ], "gene_names_uniprotkb": "grlH; DDB_G0282459", "gene_names_refseq": "grlH", "protein_names_uniprotkb": "Metabotropic glutamate receptor-like protein H", "protein_names_refseq": "G-protein-coupled receptor family 3 protein 8", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282459)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15875012;16735079;17501984;18559084", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0140985 G protein-coupled chemorepellent receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0009617 response to bacterium;GO:0140986 G protein-coupled chemorepellent receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54SH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SJ5-1", "uniprot_id": [ { "id": "MYLKC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SJ5", "type": "external" } ], "mass": 35219.0, "length": 312, "protein_name": "Probable myosin light chain kinase DDB_G0282429", "gene_name": "DDB_G0282429", "organism": "Cellular slime mold", "refseq_name": "CAMK1 family protein kinase", "refseq_ac": [ { "id": "XP_640044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640044", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282429", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable myosin light chain kinase DDB_G0282429; 2.7.11.18", "protein_names_refseq": "CAMK1 family protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282429)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May phosphorylate a specific serine in the N-terminus of a myosin light chain., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.18", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004687 myosin light chain kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54SJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SM3-1", "uniprot_id": [ { "id": "PPIA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SM3", "type": "external" } ], "mass": 19008.0, "length": 179, "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "ppiA", "organism": "Cellular slime mold", "refseq_name": "cyclophilin-type peptidylprolyl cis-trans isomerase", "refseq_ac": [ { "id": "XP_640016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640016", "type": "external" } ], "gene_names_uniprotkb": "ppiA; DDB_G0282359; cyp1", "gene_names_refseq": "ppiA", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase A; 5.2.1.8; Cyclophilin A; PPIase A; Rotamase A", "protein_names_refseq": "cyclophilin-type peptidylprolyl cis-trans isomerase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282359); (R-DDI-72163)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10575348;15470253;15875012;2049879;8643519", "class_list": "", "function": "PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006457 protein folding;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54SM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SP2-1", "uniprot_id": [ { "id": "FORB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SP2", "type": "external" } ], "mass": 123608.0, "length": 1126, "protein_name": "Formin-B", "gene_name": "forB", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_640259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640259", "type": "external" } ], "gene_names_uniprotkb": "forB; DDB_G0282297", "gene_names_refseq": "forB", "protein_names_uniprotkb": "Formin-B", "protein_names_refseq": "actin binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282297)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12538772;15726806;15740615;15875012;16762450", "class_list": "", "function": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8IU41", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0070685 macropinocytic cup;GO:0097204 phagocytic cup base", "go_biological_process": "GO:0070060 'de novo' actin filament nucleation;GO:0006911 phagocytosis, engulfment;GO:0030866 cortical actin cytoskeleton organization;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54SP2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SS8-1", "uniprot_id": [ { "id": "RGAPB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SS8", "type": "external" } ], "mass": 46889.0, "length": 418, "protein_name": "RapA guanosine triphosphatase-activating protein B", "gene_name": "rapgapB", "organism": "Cellular slime mold", "refseq_name": "RapGAP/RanGAP domain-containing protein", "refseq_ac": [ { "id": "XP_640307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640307", "type": "external" } ], "gene_names_uniprotkb": "rapgapB; DDB_G0282247", "gene_names_refseq": "rapgapB", "protein_names_uniprotkb": "RapA guanosine triphosphatase-activating protein B", "protein_names_refseq": "RapGAP/RanGAP domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282247); (R-DDI-392517)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;19126673", "class_list": "", "function": "Mediates the deactivation of rap1 during multicellular development and is required for normal morphogenesis. Also required for the correct patterning of specific subtypes of prestalk cells., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005938 cell cortex;GO:0031252 cell leading edge", "go_biological_process": "GO:0007015 actin filament organization;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0022407 regulation of cell-cell adhesion;GO:0007264 small GTPase-mediated signal transduction;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54SS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SV8-1", "uniprot_id": [ { "id": "DPOLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SV8", "type": "external" } ], "mass": 172818.0, "length": 1509, "protein_name": "DNA polymerase alpha catalytic subunit", "gene_name": "pola1", "organism": "Cellular slime mold", "refseq_name": "DNA polymerase alpha catalytic subunit", "refseq_ac": [ { "id": "XP_640277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640277", "type": "external" } ], "gene_names_uniprotkb": "pola1; DDB_G0282191", "gene_names_refseq": "polA1", "protein_names_uniprotkb": "DNA polymerase alpha catalytic subunit; 2.7.7.7", "protein_names_refseq": "DNA polymerase alpha catalytic subunit; DNA polymerase alpha-primase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282191); (R-DDI-113501); (R-DDI-68952); (R-DDI-68962); (R-DDI-69091); (R-DDI-69166); (R-DDI-69183)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Polymerase alpha in a complex with DNA primase is a replicative polymerase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" } ], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003887 DNA-directed DNA polymerase activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex", "go_biological_process": "GO:0006272 leading strand elongation;GO:0006273 lagging strand elongation;GO:0006270 DNA replication initiation;GO:1902975 mitotic DNA replication initiation;GO:0000731 DNA synthesis involved in DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54SV8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54T05-1", "uniprot_id": [ { "id": "RIO2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54T05", "type": "external" } ], "mass": 61089.0, "length": 522, "protein_name": "Serine/threonine-protein kinase rio2", "gene_name": "rio2", "organism": "Cellular slime mold", "refseq_name": "RIO family protein kinase", "refseq_ac": [ { "id": "XP_640350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640350", "type": "external" } ], "gene_names_uniprotkb": "rio2; DDB_G0282099", "gene_names_refseq": "rio2", "protein_names_uniprotkb": "Serine/threonine-protein kinase rio2; 2.7.11.1", "protein_names_refseq": "RIO family protein kinase; RIO2 subfamily protein kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282099); (R-DDI-6791226)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Required for the final endonucleolytic cleavage of 20S pre-rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.1.26.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.5", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54T05-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54T06-1", "uniprot_id": [ { "id": "Y8206_DICDI", "url": "https://www.uniprot.org/uniprot/Q54T06", "type": "external" } ], "mass": 63242.0, "length": 573, "protein_name": "Probable zinc transporter protein DDB_G0282067", "gene_name": "DDB_G0282067", "organism": "Cellular slime mold", "refseq_name": "cation diffusion facilitator family protein", "refseq_ac": [ { "id": "XP_640445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640445", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282067", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable zinc transporter protein DDB_G0282067", "protein_names_refseq": "cation diffusion facilitator family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282067); (R-DDI-425410); (R-DDI-435368)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;18590548", "class_list": "", "function": "May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0055037 recycling endosome;GO:0032010 phagolysosome;GO:0140221 pathogen-containing vacuole membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0006829 zinc ion transport;GO:0042742 defense response to bacterium;GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54T06-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54T13-1", "uniprot_id": [ { "id": "Q54T13_DICDI", "url": "https://www.uniprot.org/uniprot/Q54T13", "type": "external" } ], "mass": 53056.0, "length": 464, "protein_name": "C2 domain-containing protein", "gene_name": "DDB_G0282055", "organism": "Cellular slime mold", "refseq_name": "C2 domain-containing protein", "refseq_ac": [ { "id": "XP_640438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640438", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282055", "gene_names_refseq": "", "protein_names_uniprotkb": "C2 domain-containing protein", "protein_names_refseq": "C2 domain-containing protein; Ras GTPase activation domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282055); (R-DDI-5218921); (R-DDI-5658442); (R-DDI-8849471)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0045335 phagocytic vesicle;GO:0009898 cytoplasmic side of plasma membrane;GO:0044354 macropinosome;GO:0031256 leading edge membrane", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:2000145 regulation of cell motility;GO:1902531 regulation of intracellular signal transduction;GO:0046488 phosphatidylinositol metabolic process;GO:0050764 regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54T13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54T81-1", "uniprot_id": [ { "id": "DKC1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54T81", "type": "external" } ], "mass": 60804.0, "length": 540, "protein_name": "Probable H/ACA ribonucleoprotein complex subunit 4", "gene_name": "nola4", "organism": "Cellular slime mold", "refseq_name": "DKCLD domain-containing protein", "refseq_ac": [ { "id": "XP_640508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640508", "type": "external" } ], "gene_names_uniprotkb": "nola4; DDB_G0281933; dkc1", "gene_names_refseq": "nola4", "protein_names_uniprotkb": "Probable H/ACA ribonucleoprotein complex subunit 4; 5.4.99.-", "protein_names_refseq": "DKCLD domain-containing protein; H/ACA RNP complex subunit 4; PUA domain-containing protein; pseudouridine synthase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281933); (R-DDI-171319)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;16512674", "class_list": "", "function": "Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.4.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0003720 telomerase activity;GO:0009982 pseudouridine synthase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005697 telomerase holoenzyme complex;GO:0031429 box H/ACA snoRNP complex", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0006974 DNA damage response;GO:0046689 response to mercury ion;GO:0000495 box H/ACA sno(s)RNA 3'-end processing;GO:0031118 rRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54T81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54T86-1", "uniprot_id": [ { "id": "DWWA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54T86", "type": "external" } ], "mass": 64751.0, "length": 568, "protein_name": "WW domain-containing protein A", "gene_name": "dwwA", "organism": "Cellular slime mold", "refseq_name": "WW domain-containing protein", "refseq_ac": [ { "id": "XP_640503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640503", "type": "external" } ], "gene_names_uniprotkb": "dwwA; DDB_G0281827", "gene_names_refseq": "dwwA", "protein_names_uniprotkb": "WW domain-containing protein A", "protein_names_refseq": "WW domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281827); (R-DDI-2028269)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "14595117;15875012", "class_list": "", "function": "Involved in regulation of actin cytoskeleton organization and cytokinesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86SB0", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005516 calmodulin binding;GO:0019900 kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005938 cell cortex", "go_biological_process": "GO:0046621 negative regulation of organ growth;GO:0035330 regulation of hippo signaling;GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54T86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TA1-1", "uniprot_id": [ { "id": "DRKC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TA1", "type": "external" } ], "mass": 83465.0, "length": 749, "protein_name": "Probable serine/threonine-protein kinase drkC", "gene_name": "drkC", "organism": "Cellular slime mold", "refseq_name": "DRK subfamily protein kinase", "refseq_ac": [ { "id": "XP_640488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640488", "type": "external" } ], "gene_names_uniprotkb": "drkC; DDB_G0281899; rk3", "gene_names_refseq": "drkC", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase drkC; 2.7.11.1; Receptor-like kinase 3; Receptor-like kinase C; Vesicle-associated receptor tyrosine kinase-like protein 3", "protein_names_refseq": "DRK subfamily protein kinase; E set domain-containing protein; protein kinase, TKL group; protein tyrosine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281899); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030670 phagocytic vesicle membrane;GO:0032010 phagolysosome", "go_biological_process": "GO:0007165 signal transduction;GO:0006909 phagocytosis;GO:0001845 phagolysosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TC2-1", "uniprot_id": [ { "id": "ADHX_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TC2", "type": "external" } ], "mass": 40553.0, "length": 379, "protein_name": "Alcohol dehydrogenase class-3", "gene_name": "adh5", "organism": "Cellular slime mold", "refseq_name": "alcohol dehydrogenase, class 3", "refseq_ac": [ { "id": "XP_640467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640467", "type": "external" } ], "gene_names_uniprotkb": "adh5; DDB_G0281865", "gene_names_refseq": "adh5", "protein_names_uniprotkb": "Alcohol dehydrogenase class-3; 1.1.1.-; 1.1.1.1; 1.1.1.284; Alcohol dehydrogenase class-III; FALDH; FDH; GSH-FDH; Glutathione-dependent formaldehyde dehydrogenase; S-(hydroxymethyl)glutathione dehydrogenase", "protein_names_refseq": "alcohol dehydrogenase, class 3; formaldehyde dehydrogenase; zinc-containing alcohol dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281865); (R-DDI-211935); (R-DDI-2161541); (R-DDI-5365859); (R-DDI-71384)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.-", "type": "external" }, { "id": "1.1.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.1", "type": "external" }, { "id": "1.1.1.284", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.284", "type": "external" } ], "go_molecular_function": "GO:0004022 alcohol dehydrogenase (NAD+) activity;GO:0008270 zinc ion binding;GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity;GO:0106321 S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity;GO:0106322 S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046294 formaldehyde catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TF8-1", "uniprot_id": [ { "id": "DDX19_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TF8", "type": "external" } ], "mass": 51720.0, "length": 465, "protein_name": "ATP-dependent RNA helicase ddx19", "gene_name": "helC", "organism": "Cellular slime mold", "refseq_name": "DEAD-box RNA helicase", "refseq_ac": [ { "id": "XP_640633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640633", "type": "external" } ], "gene_names_uniprotkb": "helC; DDB_G0281553; ddx19", "gene_names_refseq": "helC", "protein_names_uniprotkb": "ATP-dependent RNA helicase ddx19; 3.6.4.13; ATP-dependent RNA helicase helC; DEAD box protein 19", "protein_names_refseq": "DEAD-box RNA helicase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281553)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;9601648", "class_list": "", "function": "ATP-binding RNA helicase required for normal differentiation and development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O00898", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0010628 positive regulation of gene expression;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54TF8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TL0-1", "uniprot_id": [ { "id": "KIF7_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TL0", "type": "external" } ], "mass": 141959.0, "length": 1255, "protein_name": "Kinesin-related protein 7", "gene_name": "kif7", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 7", "refseq_ac": [ { "id": "XP_640581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640581", "type": "external" } ], "gene_names_uniprotkb": "kif7; DDB_G0281555; K7; ksnG", "gene_names_refseq": "kif7", "protein_names_uniprotkb": "Kinesin-related protein 7; Kinesin family member 7; Kinesin-1", "protein_names_refseq": "kinesin family member 7", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281555)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14641909;15875012;9693369", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. May be involved in cell motility or cell differentiation during prestalk formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q94463", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0031965 nuclear membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005871 kinesin complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0030705 cytoskeleton-dependent intracellular transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54TL0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TM2-1", "uniprot_id": [ { "id": "LMD2B_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TM2", "type": "external" } ], "mass": 88926.0, "length": 790, "protein_name": "LMBR1 domain-containing protein 2 homolog B", "gene_name": "DDB_G0281669", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640569", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0281669", "gene_names_refseq": "", "protein_names_uniprotkb": "LMBR1 domain-containing protein 2 homolog B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281669)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery;GO:0001726 ruffle;GO:0031941 filamentous actin", "go_biological_process": "GO:0031268 pseudopodium organization;GO:0006897 endocytosis;GO:0006935 chemotaxis;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TM2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TM7-1", "uniprot_id": [ { "id": "DRKD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TM7", "type": "external" } ], "mass": 147339.0, "length": 1288, "protein_name": "Probable serine/threonine-protein kinase drkD", "gene_name": "drkD", "organism": "Cellular slime mold", "refseq_name": "DRK subfamily protein kinase", "refseq_ac": [ { "id": "XP_640564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640564", "type": "external" } ], "gene_names_uniprotkb": "drkD; DDB_G0281557; rsc21", "gene_names_refseq": "drkD", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase drkD; 2.7.11.1; Receptor-like kinase D", "protein_names_refseq": "DRK subfamily protein kinase; leucine-rich repeat-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281557); (R-DDI-168638); (R-DDI-170968); (R-DDI-3295583); (R-DDI-392517); (R-DDI-5213460); (R-DDI-5621575); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5674499); (R-DDI-5675221); (R-DDI-5675482); (R-DDI-5689880)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15912", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0050829 defense response to Gram-negative bacterium;GO:0050765 negative regulation of phagocytosis;GO:2000146 negative regulation of cell motility;GO:0051593 response to folic acid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TM7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TN2-1", "uniprot_id": [ { "id": "MYBC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TN2", "type": "external" } ], "mass": 65993.0, "length": 580, "protein_name": "Myb-like protein C", "gene_name": "mybC", "organism": "Cellular slime mold", "refseq_name": "myb transcription factor", "refseq_ac": [ { "id": "XP_640559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640559", "type": "external" } ], "gene_names_uniprotkb": "mybC; DDB_G0281563", "gene_names_refseq": "mybC", "protein_names_uniprotkb": "Myb-like protein C", "protein_names_refseq": "myb transcription factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281563)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10331990;15875012", "class_list": "", "function": "Transcription activator required for the culmination, at the time of the fruiting body formation. Regulates genes involved in the cell differentiation within the fruiting body., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2V061;Q9GUB3", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0006355 regulation of DNA-templated transcription;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54TN2-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TR1-1", "uniprot_id": [ { "id": "CFAD_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TR1", "type": "external" } ], "mass": 58638.0, "length": 531, "protein_name": "Counting factor associated protein D", "gene_name": "cfaD", "organism": "Cellular slime mold", "refseq_name": "cathepsin L-like proteinase", "refseq_ac": [ { "id": "XP_640530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640530", "type": "external" } ], "gene_names_uniprotkb": "cfaD; DDB_G0281605", "gene_names_refseq": "cfaD", "protein_names_uniprotkb": "Counting factor associated protein D", "protein_names_refseq": "cathepsin L-like proteinase; counting factor associated protein; peptidase C1A family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281605); (R-DDI-2132295); (R-DDI-5683826); (R-DDI-6798695)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "15875012;18611962;19187549", "class_list": "", "function": "Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005764 lysosome;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006508 proteolysis;GO:0006955 immune response;GO:0072659 protein localization to plasma membrane;GO:2001235 positive regulation of apoptotic signaling pathway;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54TR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TW2-1", "uniprot_id": [ { "id": "PDPKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TW2", "type": "external" } ], "mass": 75562.0, "length": 686, "protein_name": "Probable serine/threonine-protein kinase pdkA", "gene_name": "pdkA", "organism": "Cellular slime mold", "refseq_name": "PDK1 family protein kinase", "refseq_ac": [ { "id": "XP_640699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640699", "type": "external" } ], "gene_names_uniprotkb": "pdkA; DDB_G0281471", "gene_names_refseq": "pdkA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase pdkA; 2.7.11.1; 3-phosphoinositide-dependent protein kinase A; Pdk-class protein kinase A", "protein_names_refseq": "PDK1 family protein kinase; protein kinase, AGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281471); (R-DDI-114604); (R-DDI-1257604); (R-DDI-165158); (R-DDI-202424); (R-DDI-2730905); (R-DDI-389357); (R-DDI-392451); (R-DDI-5218920); (R-DDI-5218921); (R-DDI-6804757); (R-DDI-9634635); (R-DDI-9856530)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030295 protein kinase activator activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:1905303 positive regulation of macropinocytosis;GO:0098630 aggregation of unicellular organisms;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TY7-1", "uniprot_id": [ { "id": "SRFA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TY7", "type": "external" } ], "mass": 47546.0, "length": 418, "protein_name": "Serum response factor homolog A", "gene_name": "srfA", "organism": "Cellular slime mold", "refseq_name": "MADS-box transcription factor", "refseq_ac": [ { "id": "XP_640674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640674", "type": "external" } ], "gene_names_uniprotkb": "srfA; DDB_G0281387", "gene_names_refseq": "srfA", "protein_names_uniprotkb": "Serum response factor homolog A; DsSRF", "protein_names_refseq": "MADS-box transcription factor; SRF-related protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281387); (R-DDI-9031628)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "11437439;12204259;14706699;15875012;9729488", "class_list": "", "function": "Required for proper slug migration, spore differentiation and stalk differentiation (under nonbuffered conditions). Could be involved in late events of spore maturation necessary for spore stability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76853", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0031247 actin rod assembly;GO:0042331 phototaxis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54TY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54U71-1", "uniprot_id": [ { "id": "COQ2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54U71", "type": "external" } ], "mass": 51925.0, "length": 463, "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "gene_name": "coq2", "organism": "Cellular slime mold", "refseq_name": "4-hydroxybenzoate nonaprenyltransferase", "refseq_ac": [ { "id": "XP_640905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640905", "type": "external" } ], "gene_names_uniprotkb": "coq2; DDB_G0281241", "gene_names_refseq": "coq2", "protein_names_uniprotkb": "4-hydroxybenzoate polyprenyltransferase, mitochondrial; 2.5.1.39; 4-HB polyprenyltransferase; PHB:PPT; PHB:polyprenyltransferase; Para-hydroxybenzoate--polyprenyltransferase", "protein_names_refseq": "4-hydroxybenzoate nonaprenyltransferase; para-hydroxybenzoate nonaprenyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281241); (R-DDI-1268020); (R-DDI-2142789)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.39", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" } ], "go_molecular_function": "GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0008412 4-hydroxybenzoate polyprenyltransferase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0008299 isoprenoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54U71-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54U72-1", "uniprot_id": [ { "id": "IMPA1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54U72", "type": "external" } ], "mass": 29899.0, "length": 272, "protein_name": "Inositol monophosphatase", "gene_name": "impa1", "organism": "Cellular slime mold", "refseq_name": "inositol monophosphatase", "refseq_ac": [ { "id": "XP_640904", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640904", "type": "external" } ], "gene_names_uniprotkb": "impa1; DDB_G0281239", "gene_names_refseq": "impa1", "protein_names_uniprotkb": "Inositol monophosphatase; 3.1.3.25; 3.1.3.94; D-galactose 1-phosphate phosphatase; IMPase; IMP; Inositol-1(or 4)-monophosphatase", "protein_names_refseq": "inositol monophosphatase; inositol-phosphate phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281239); (R-DDI-1855183)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.94", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.94", "type": "external" }, { "id": "3.1.3.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.25", "type": "external" } ], "go_molecular_function": "GO:0031403 lithium ion binding;GO:0052834 inositol monophosphate phosphatase activity;GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0008934 inositol monophosphate 1-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006020 inositol metabolic process;GO:0007165 signal transduction;GO:0010226 response to lithium ion;GO:0006661 phosphatidylinositol biosynthetic process;GO:0006021 inositol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54U72-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54U75-1", "uniprot_id": [ { "id": "CRLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54U75", "type": "external" } ], "mass": 42976.0, "length": 369, "protein_name": "Cyclic AMP receptor-like protein A", "gene_name": "crlA", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family protein", "refseq_ac": [ { "id": "XP_640901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640901", "type": "external" } ], "gene_names_uniprotkb": "crlA; DDB_G0280983", "gene_names_refseq": "crlA", "protein_names_uniprotkb": "Cyclic AMP receptor-like protein A", "protein_names_refseq": "G-protein-coupled receptor family protein; cAMP receptor-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280983)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14732403;15875012;16735079", "class_list": "", "function": "Receptor for cAMP which may play a role in prestalk cell differentiation. May act as a negative regulator of cell growth., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86GL6", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0001646 cAMP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0030308 negative regulation of cell growth;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54U75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54U87-1", "uniprot_id": [ { "id": "DHKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54U87", "type": "external" } ], "mass": 239636.0, "length": 2150, "protein_name": "Hybrid signal transduction histidine kinase A", "gene_name": "dhkA", "organism": "Cellular slime mold", "refseq_name": "HisK family protein kinase", "refseq_ac": [ { "id": "XP_640889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640889", "type": "external" } ], "gene_names_uniprotkb": "dhkA; DDB_G0280961", "gene_names_refseq": "dhkA", "protein_names_uniprotkb": "Hybrid signal transduction histidine kinase A; 2.7.13.3", "protein_names_refseq": "HisK family protein kinase; histidine kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280961)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10373524;15875012;15897458;8670894", "class_list": "", "function": "Acts as a receptor histidine kinase for the cytokinin SDF-2 in a signal transduction pathway that regulates prestalk gene expression and controls terminal differentiation of prespore cells. Binding of SDF-2 to this protein inhibits phosphorelay and induces rapid sporulation. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q23863", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000155 phosphorelay sensor kinase activity;GO:0009784 transmembrane receptor histidine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0009736 cytokinin-activated signaling pathway;GO:0030587 sorocarp development;GO:0031150 sorocarp stalk development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54U87-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54U89-1", "uniprot_id": [ { "id": "GRLL_DICDI", "url": "https://www.uniprot.org/uniprot/Q54U89", "type": "external" } ], "mass": 78003.0, "length": 708, "protein_name": "Metabotropic glutamate receptor-like protein L", "gene_name": "far1", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family 3 protein 11", "refseq_ac": [ { "id": "XP_640887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640887", "type": "external" } ], "gene_names_uniprotkb": "far1; DDB_G0281211; grlL", "gene_names_refseq": "grlL", "protein_names_uniprotkb": "Metabotropic glutamate receptor-like protein L", "protein_names_refseq": "G-protein-coupled receptor family 3 protein 11", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281211)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15875012;16735079;17501984;18590548", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0019887 protein kinase regulator activity;GO:0001530 lipopolysaccharide binding;GO:0005542 folic acid binding;GO:0106063 G protein-coupled folate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0006911 phagocytosis, engulfment;GO:0007186 G protein-coupled receptor signaling pathway;GO:0050829 defense response to Gram-negative bacterium;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54U89-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UC0-1", "uniprot_id": [ { "id": "PRKDC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UC0", "type": "external" } ], "mass": 494476.0, "length": 4299, "protein_name": "DNA-dependent protein kinase catalytic subunit", "gene_name": "dnapkcs", "organism": "Cellular slime mold", "refseq_name": "DNA-dependent protein kinase subunit", "refseq_ac": [ { "id": "XP_640856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640856", "type": "external" } ], "gene_names_uniprotkb": "dnapkcs; DDB_G0281167", "gene_names_refseq": "dnapkcs", "protein_names_uniprotkb": "DNA-dependent protein kinase catalytic subunit; 2.7.11.1; DNA-PK catalytic subunit; DNA-PKcs", "protein_names_refseq": "DNA-dependent protein kinase subunit; DNAPK subfamily protein kinase; PIKK family protein kinase; phosphatidylinositol 3-kinase-related protein kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281167); (R-DDI-5693571)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "15875012;16243037;16596165", "class_list": "", "function": "Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004677 DNA-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0000723 telomere maintenance;GO:0006974 DNA damage response;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0042770 signal transduction in response to DNA damage", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54UC0-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UC9-1", "uniprot_id": [ { "id": "KIF3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UC9", "type": "external" } ], "mass": 130532.0, "length": 1193, "protein_name": "Kinesin-related protein 3", "gene_name": "kif3", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 3", "refseq_ac": [ { "id": "XP_640847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640847", "type": "external" } ], "gene_names_uniprotkb": "kif3; DDB_G0280967; K3; ksnC", "gene_names_refseq": "kif3", "protein_names_uniprotkb": "Kinesin-related protein 3; Kinesin family member 3; Kinesin-1", "protein_names_refseq": "kinesin family member 3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280967)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10545495;12952062;14641909;15875012;18160177;9693369", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. The maximal velocity in an inverted motility assay (moving microtubules on fixed motors) was 1.96 um/s., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O15720;Q6S005;Q8I825", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0030705 cytoskeleton-dependent intracellular transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54UC9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UF3-1", "uniprot_id": [ { "id": "DCOR_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UF3", "type": "external" } ], "mass": 51695.0, "length": 461, "protein_name": "Probable ornithine decarboxylase", "gene_name": "odc", "organism": "Cellular slime mold", "refseq_name": "Orn/DAP/Arg decarboxylase 2 domain-containing protein", "refseq_ac": [ { "id": "XP_640823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640823", "type": "external" } ], "gene_names_uniprotkb": "odc; DDB_G0281109", "gene_names_refseq": "odc", "protein_names_uniprotkb": "Probable ornithine decarboxylase; 4.1.1.17; ODC", "protein_names_refseq": "Orn/DAP/Arg decarboxylase 2 domain-containing protein; group IV decarboxylase; ornithine decarboxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281109); (R-DDI-351143); (R-DDI-351202)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.17", "type": "external" } ], "go_molecular_function": "GO:0004586 ornithine decarboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0009446 putrescine biosynthetic process;GO:0033387 putrescine biosynthetic process from arginine, via ornithine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54UF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UI6-1", "uniprot_id": [ { "id": "Q54UI6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UI6", "type": "external" } ], "mass": 263277.0, "length": 2285, "protein_name": "RNA-directed RNA polymerase", "gene_name": "rrpC", "organism": "Cellular slime mold", "refseq_name": "RNA-directed RNA polymerase", "refseq_ac": [ { "id": "XP_640790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640790", "type": "external" } ], "gene_names_uniprotkb": "rrpC; DDB_G0280963", "gene_names_refseq": "rrpC", "protein_names_uniprotkb": "RNA-directed RNA polymerase", "protein_names_refseq": "RNA-directed RNA polymerase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280963)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003968 RNA-directed RNA polymerase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0031380 nuclear RNA-directed RNA polymerase complex", "go_biological_process": "GO:0010586 miRNA metabolic process;GO:0030422 siRNA processing;GO:0016441 post-transcriptional gene silencing;GO:0010587 miRNA catabolic process;GO:1990514 5' transitive RNA interference", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54UI6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UK0-1", "uniprot_id": [ { "id": "PLDA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UK0", "type": "external" } ], "mass": 142142.0, "length": 1269, "protein_name": "Phospholipase D A", "gene_name": "pldA", "organism": "Cellular slime mold", "refseq_name": "phospholipase D1", "refseq_ac": [ { "id": "XP_640776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640776", "type": "external" } ], "gene_names_uniprotkb": "pldA; DDB_G0281031; pld1", "gene_names_refseq": "pldA", "protein_names_uniprotkb": "Phospholipase D A; 3.1.4.4; PLD 1; Phosphatase D1", "protein_names_refseq": "phospholipase D1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281031); (R-DDI-1483166); (R-DDI-2029485); (R-DDI-6798695); (R-DDI-9013149); (R-DDI-9013404)", "pathway_count": 6, "publication_count": 7, "publication_id_list": "15225639;15769249;15821129;15875012;16762450;6498208;8394342", "class_list": "", "function": "Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0004630 phospholipase D activity", "go_cellular_component": "", "go_biological_process": "GO:0009395 phospholipid catabolic process;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q54UK0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UL8-1", "uniprot_id": [ { "id": "MPS1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UL8", "type": "external" } ], "mass": 113573.0, "length": 983, "protein_name": "Probable serine/threonine-protein kinase mps1", "gene_name": "mps1", "organism": "Cellular slime mold", "refseq_name": "TTK family protein kinase", "refseq_ac": [ { "id": "XP_640758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640758", "type": "external" } ], "gene_names_uniprotkb": "mps1; DDB_G0280995; ttkA", "gene_names_refseq": "mps1", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase mps1; 2.7.11.1; Monopolar spindle protein 1", "protein_names_refseq": "TTK family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280995)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15548420;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0000776 kinetochore", "go_biological_process": "GO:0033316 meiotic spindle assembly checkpoint signaling;GO:0007059 chromosome segregation;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0034501 protein localization to kinetochore", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54UL8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UT2-1", "uniprot_id": [ { "id": "DGK_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UT2", "type": "external" } ], "mass": 33193.0, "length": 285, "protein_name": "Deoxyguanosine kinase", "gene_name": "dgk", "organism": "Cellular slime mold", "refseq_name": "deoxyguanosine kinase", "refseq_ac": [ { "id": "XP_641009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641009", "type": "external" } ], "gene_names_uniprotkb": "dgk; DDB_G0280843", "gene_names_refseq": "dgk", "protein_names_uniprotkb": "Deoxyguanosine kinase; 2.7.1.113; DddGK; dGK", "protein_names_refseq": "deoxyguanosine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280843)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17448496", "class_list": "", "function": "Purine-specific deoxyribonucleoside kinase that phosphorylates preferentially deoxyguanosine, as part of the deoxyribonucleotide salvage pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q14EL5", "ec_number_list": [ { "id": "2.7.1.113", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.113", "type": "external" } ], "go_molecular_function": "GO:0004138 deoxyguanosine kinase activity;GO:0005524 ATP binding;GO:0008137 NADH dehydrogenase (ubiquinone) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0006120 mitochondrial electron transport, NADH to ubiquinone;GO:0006180 deoxyguanosine salvage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54UT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UU3-1", "uniprot_id": [ { "id": "RS6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UU3", "type": "external" } ], "mass": 26166.0, "length": 236, "protein_name": "Small ribosomal subunit protein eS6", "gene_name": "rps6", "organism": "Cellular slime mold", "refseq_name": "40S ribosomal protein S6", "refseq_ac": [ { "id": "XP_640998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640998", "type": "external" } ], "gene_names_uniprotkb": "rps6; DDB_G0280823", "gene_names_refseq": "rps6", "protein_names_uniprotkb": "Small ribosomal subunit protein eS6; 40S ribosomal protein S6", "protein_names_refseq": "40S ribosomal protein S6", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280823); (R-DDI-156827); (R-DDI-166208); (R-DDI-1799339); (R-DDI-6791226); (R-DDI-72689); (R-DDI-72695); (R-DDI-72702); (R-DDI-72706); (R-DDI-9629569); (R-DDI-975956); (R-DDI-975957); (R-DDI-9954714); (R-DDI-9954716)", "pathway_count": 14, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005938 cell cortex;GO:0031012 extracellular matrix;GO:0005840 ribosome;GO:0070938 contractile ring;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006412 translation;GO:0000281 mitotic cytokinesis;GO:0042274 ribosomal small subunit biogenesis;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54UU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54UW5-1", "uniprot_id": [ { "id": "RUVB2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54UW5", "type": "external" } ], "mass": 51971.0, "length": 469, "protein_name": "RuvB-like helicase 2", "gene_name": "rvb2", "organism": "Cellular slime mold", "refseq_name": "AAA ATPase domain-containing protein", "refseq_ac": [ { "id": "XP_641022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641022", "type": "external" } ], "gene_names_uniprotkb": "rvb2; DDB_G0280775", "gene_names_refseq": "rvb2", "protein_names_uniprotkb": "RuvB-like helicase 2; 3.6.4.12", "protein_names_refseq": "AAA ATPase domain-containing protein; RuvB-like protein 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280775)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Has double-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity suggesting a role in nuclear processes such as recombination and transcription., [UniProtKB]; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0097255 R2TP complex;GO:0031011 Ino80 complex;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54UW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V07-1", "uniprot_id": [ { "id": "TGRB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V07", "type": "external" } ], "mass": 100319.0, "length": 902, "protein_name": "Tiger protein B1", "gene_name": "tgrB1", "organism": "Cellular slime mold", "refseq_name": "IPT/TIG domain-containing protein", "refseq_ac": [ { "id": "XP_641124", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641124", "type": "external" } ], "gene_names_uniprotkb": "tgrB1; DDB_G0280689; lagB1; lagB", "gene_names_refseq": "tgrB1", "protein_names_uniprotkb": "Tiger protein B1; Loose aggregate B1 protein; Transmembrane, IPT, Ig, E-set, Repeat protein B1", "protein_names_refseq": "IPT/TIG domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280689)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15875012;19285397;23477311;24490801;26395484;29038229", "class_list": "", "function": "tgrB1 and tgrC1 are involved in kin discrimination; function as a ligand-receptor pair, where tgrB1 serves as a receptor. They play an essential role in cell-cell adhesion, aggregation and subsequent development into multicellular forms., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 19, "predicted_n_glycosites": 19, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 19, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0098635 protein complex involved in cell-cell adhesion", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0048870 cell motility;GO:0009988 cell-cell recognition;GO:0097656 cell-cell self recognition", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54V07-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54VA2-1", "uniprot_id": [ { "id": "FUMH_DICDI", "url": "https://www.uniprot.org/uniprot/Q54VA2", "type": "external" } ], "mass": 52963.0, "length": 485, "protein_name": "Fumarate hydratase, mitochondrial", "gene_name": "fumH", "organism": "Cellular slime mold", "refseq_name": "fumarate hydratase", "refseq_ac": [ { "id": "XP_001134561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001134561", "type": "external" } ], "gene_names_uniprotkb": "fumH; DDB_G0280495", "gene_names_refseq": "fumH", "protein_names_uniprotkb": "Fumarate hydratase, mitochondrial; 4.2.1.2; Fumarase", "protein_names_refseq": "fumarate hydratase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280495); (R-DDI-71403); (R-DDI-9837999)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH., [UniProtKB, UniProtKB]; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54VA1", "ec_number_list": [ { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "1.3.8.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.-", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.3.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.16", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0004333 fumarate hydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006106 fumarate metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0009617 response to bacterium;GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54VA2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54VB6-1", "uniprot_id": [ { "id": "PSRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54VB6", "type": "external" } ], "mass": 73394.0, "length": 628, "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit psrA", "gene_name": "psrA", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase 2A regulatory subunit", "refseq_ac": [ { "id": "XP_641193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641193", "type": "external" } ], "gene_names_uniprotkb": "psrA; B56; DB56; DDB_G0280469", "gene_names_refseq": "psrA", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A regulatory subunit psrA; Protein PPP2R5A/B56 homolog; Protein phosphatase 2A regulatory B subunit; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; protein phosphatase 2A B56 regulatory subunit homolog", "protein_names_refseq": "protein phosphatase 2A regulatory subunit; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280469); (R-DDI-198753); (R-DDI-202670); (R-DDI-389513); (R-DDI-5675221); (R-DDI-6811558); (R-DDI-9833482)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "15875012;18673380", "class_list": "", "function": "Involved in developmental cell fate decision., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008603 cAMP-dependent protein kinase regulator activity;GO:0019888 protein phosphatase regulator activity;GO:0031267 small GTPase binding;GO:0030695 GTPase regulator activity;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:1904643 response to curcumin;GO:0007165 signal transduction;GO:0030154 cell differentiation;GO:0048870 cell motility;GO:0051177 meiotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54VB6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54VD8-1", "uniprot_id": [ { "id": "RIO1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54VD8", "type": "external" } ], "mass": 67270.0, "length": 574, "protein_name": "Serine/threonine-protein kinase rio1", "gene_name": "rio1", "organism": "Cellular slime mold", "refseq_name": "RIO family protein kinase", "refseq_ac": [ { "id": "XP_641171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641171", "type": "external" } ], "gene_names_uniprotkb": "rio1; DDB_G0280431", "gene_names_refseq": "rio1", "protein_names_uniprotkb": "Serine/threonine-protein kinase rio1; 2.7.11.1; 3.6.1.-", "protein_names_refseq": "RIO family protein kinase; RIO1 subfamily protein kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280431); (R-DDI-6791226)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Required for the final endonucleolytic cleavage at site D converting 20S pre-rRNA into the mature 18S rRNA. Required for the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.1.26.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.5", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54VD8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54VI1-1", "uniprot_id": [ { "id": "FHKE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54VI1", "type": "external" } ], "mass": 79684.0, "length": 712, "protein_name": "Probable serine/threonine-protein kinase fhkE", "gene_name": "fhkE", "organism": "Cellular slime mold", "refseq_name": "FHA domain-containing protein", "refseq_ac": [ { "id": "XP_641374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641374", "type": "external" } ], "gene_names_uniprotkb": "fhkE; DDB_G0280321; fhake", "gene_names_refseq": "fhkE", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase fhkE; 2.7.11.1; Forkhead-associated kinase protein E", "protein_names_refseq": "FHA domain-containing protein; RAD53 family protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280321)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0044773 mitotic DNA damage checkpoint signaling;GO:0006974 DNA damage response;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54VI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54VI3-1", "uniprot_id": [ { "id": "GLUD2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54VI3", "type": "external" } ], "mass": 117144.0, "length": 1042, "protein_name": "Glutamate dehydrogenase 2", "gene_name": "glud2", "organism": "Cellular slime mold", "refseq_name": "NAD+ dependent glutamate dehydrogenase", "refseq_ac": [ { "id": "XP_641372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641372", "type": "external" } ], "gene_names_uniprotkb": "glud2; DDB_G0280319", "gene_names_refseq": "glud2", "protein_names_uniprotkb": "Glutamate dehydrogenase 2; 1.4.1.2; NAD-GDH; NAD-specific glutamate dehydrogenase", "protein_names_refseq": "NAD+ dependent glutamate dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280319)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1402793;15875012;1952936;33476647;8728102", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "1.4.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.2", "type": "external" } ], "go_molecular_function": "GO:0004352 glutamate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006538 L-glutamate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54VI3-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54VQ5-1", "uniprot_id": [ { "id": "GADA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54VQ5", "type": "external" } ], "mass": 52621.0, "length": 462, "protein_name": "Glutamate decarboxylase A", "gene_name": "gadA", "organism": "Cellular slime mold", "refseq_name": "glutamate decarboxylase", "refseq_ac": [ { "id": "XP_641300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641300", "type": "external" } ], "gene_names_uniprotkb": "gadA; DDB_G0280199", "gene_names_refseq": "gadA", "protein_names_uniprotkb": "Glutamate decarboxylase A; 4.1.1.15", "protein_names_refseq": "glutamate decarboxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280199)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11553701;15875012;16672332;18559084", "class_list": "", "function": "Generates GABA from glutamate. GABA induces the release of acbA from prespore cells and induces the exposure of tagC on the surface of prestalk cells where it can convert acbA to SDF-2. Glutamate acts as a competitive inhibitor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.15", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004351 glutamate decarboxylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006538 L-glutamate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54VQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54W07-1", "uniprot_id": [ { "id": "BUD32_DICDI", "url": "https://www.uniprot.org/uniprot/Q54W07", "type": "external" } ], "mass": 28577.0, "length": 252, "protein_name": "EKC/KEOPS complex subunit bud32", "gene_name": "bud32", "organism": "Cellular slime mold", "refseq_name": "BUD32 family protein kinase", "refseq_ac": [ { "id": "XP_641443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641443", "type": "external" } ], "gene_names_uniprotkb": "bud32; DDB_G0279977", "gene_names_refseq": "bud32", "protein_names_uniprotkb": "EKC/KEOPS complex subunit bud32; 2.7.11.1; 3.6.-.-; Atypical serine/threonine protein kinase bud32", "protein_names_refseq": "BUD32 family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279977)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Bud32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit osgep (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000408 EKC/KEOPS complex", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0008033 tRNA processing;GO:0070525 tRNA threonylcarbamoyladenosine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54W07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54W19-1", "uniprot_id": [ { "id": "ABCD1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54W19", "type": "external" } ], "mass": 84377.0, "length": 734, "protein_name": "ABC transporter D family member 1", "gene_name": "abcD1", "organism": "Cellular slime mold", "refseq_name": "ABC transporter D family protein", "refseq_ac": [ { "id": "XP_641431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641431", "type": "external" } ], "gene_names_uniprotkb": "abcD1; DDB_G0279917", "gene_names_refseq": "abcD1", "protein_names_uniprotkb": "ABC transporter D family member 1; ABC transporter ABCD.1", "protein_names_refseq": "ABC transporter D family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279917)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0043190 ATP-binding cassette (ABC) transporter complex", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0042760 very long-chain fatty acid catabolic process;GO:0007031 peroxisome organization;GO:0015910 long-chain fatty acid import into peroxisome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54W19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54W86-1", "uniprot_id": [ { "id": "MYLKF_DICDI", "url": "https://www.uniprot.org/uniprot/Q54W86", "type": "external" } ], "mass": 102891.0, "length": 928, "protein_name": "Probable myosin light chain kinase DDB_G0279831", "gene_name": "DDB_G0279831", "organism": "Cellular slime mold", "refseq_name": "CAMK1 family protein kinase", "refseq_ac": [ { "id": "XP_641506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641506", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0279831", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable myosin light chain kinase DDB_G0279831; 2.7.11.18", "protein_names_refseq": "CAMK1 family protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279831)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May phosphorylate a specific serine in the N-terminus of a myosin light chain., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.18", "type": "external" } ], "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0004687 myosin light chain kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54W86-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54W90-1", "uniprot_id": [ { "id": "SEY1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54W90", "type": "external" } ], "mass": 104017.0, "length": 894, "protein_name": "Protein SEY1 homolog", "gene_name": "DDB_0206311", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641502", "type": "external" } ], "gene_names_uniprotkb": "DDB_0206311", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein SEY1 homolog; 3.6.5.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279823)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable GTP-binding protein that may be involved in cell development., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0020003 symbiont-containing vacuole;GO:0140221 pathogen-containing vacuole membrane", "go_biological_process": "GO:0007033 vacuole organization;GO:0007029 endoplasmic reticulum organization;GO:0016320 endoplasmic reticulum membrane fusion;GO:1903371 regulation of endoplasmic reticulum tubular network organization;GO:1900101 regulation of endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54W90-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WG6-1", "uniprot_id": [ { "id": "H2AX_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WG6", "type": "external" } ], "mass": 16824.0, "length": 154, "protein_name": "Histone H2AX", "gene_name": "H2AX", "organism": "Cellular slime mold", "refseq_name": "histone H2A", "refseq_ac": [ { "id": "XP_641587", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641587", "type": "external" } ], "gene_names_uniprotkb": "H2AX; DDB_G0279667", "gene_names_refseq": "H2AX", "protein_names_uniprotkb": "Histone H2AX; H2a/x; Histone H2A.X", "protein_names_refseq": "histone H2A", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279667); (R-DDI-2299718); (R-DDI-2559580); (R-DDI-3214815); (R-DDI-3214858); (R-DDI-5689880); (R-DDI-5689901); (R-DDI-5693565); (R-DDI-68616); (R-DDI-73772); (R-DDI-9909649); (R-DDI-9943411); (R-DDI-9943962)", "pathway_count": 13, "publication_count": 2, "publication_id_list": "15875012;16243037", "class_list": "", "function": "Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Phosphorylation of H2AX seems to be performed by atr1 and/or possibly dnapkcs, as ATM ortholog is absent in the genome of this organism., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54WG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WH2-1", "uniprot_id": [ { "id": "FORA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WH2", "type": "external" } ], "mass": 135329.0, "length": 1218, "protein_name": "Formin-A", "gene_name": "forA", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_641581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641581", "type": "external" } ], "gene_names_uniprotkb": "forA; DDB_G0279607", "gene_names_refseq": "forA", "protein_names_uniprotkb": "Formin-A", "protein_names_refseq": "actin binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279607)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12538772;15726806;15740615;15875012;16762450", "class_list": "", "function": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IU42", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0035091 phosphatidylinositol binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0032154 cleavage furrow;GO:0031254 cell trailing edge", "go_biological_process": "GO:0070060 'de novo' actin filament nucleation;GO:0016477 cell migration;GO:0030866 cortical actin cytoskeleton organization;GO:0000281 mitotic cytokinesis;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54WH2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WH5-1", "uniprot_id": [ { "id": "ELMOE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WH5", "type": "external" } ], "mass": 186261.0, "length": 1677, "protein_name": "ELMO domain-containing protein E", "gene_name": "elmoE", "organism": "Cellular slime mold", "refseq_name": "engulfment and cell motility ELM family protein", "refseq_ac": [ { "id": "XP_641578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641578", "type": "external" } ], "gene_names_uniprotkb": "elmoE; DDB_G0279657", "gene_names_refseq": "elmoE", "protein_names_uniprotkb": "ELMO domain-containing protein E", "protein_names_refseq": "engulfment and cell motility ELM family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279657); (R-DDI-8849471)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031681 G-protein beta-subunit binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031252 cell leading edge;GO:0044354 macropinosome", "go_biological_process": "GO:0007015 actin filament organization;GO:0030041 actin filament polymerization;GO:0048870 cell motility;GO:0043327 chemotaxis to cAMP;GO:1903013 response to differentiation-inducing factor 1", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54WH5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WI0-1", "uniprot_id": [ { "id": "Q54WI0_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WI0", "type": "external" } ], "mass": 146118.0, "length": 1333, "protein_name": "Ankyrin repeat-containing protein", "gene_name": "DDB_G0279649", "organism": "Cellular slime mold", "refseq_name": "Arf GTPase activating protein", "refseq_ac": [ { "id": "XP_641573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641573", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0279649", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat-containing protein", "protein_names_refseq": "Arf GTPase activating protein; BAR domain-containing protein; ankyrin repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279649)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0031941 filamentous actin;GO:0000242 pericentriolar material", "go_biological_process": "GO:0006897 endocytosis;GO:0009617 response to bacterium;GO:0030036 actin cytoskeleton organization;GO:0007040 lysosome organization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54WI0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WJ0-1", "uniprot_id": [ { "id": "STK11_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WJ0", "type": "external" } ], "mass": 66252.0, "length": 586, "protein_name": "Serine/threonine-protein kinase stk11 homolog", "gene_name": "lkb1", "organism": "Cellular slime mold", "refseq_name": "CAMKL family protein kinase", "refseq_ac": [ { "id": "XP_641563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641563", "type": "external" } ], "gene_names_uniprotkb": "lkb1; DDB_G0279629", "gene_names_refseq": "lkb1", "protein_names_uniprotkb": "Serine/threonine-protein kinase stk11 homolog; 2.7.11.1; Liver kinase B1 homolog; lkb1", "protein_names_refseq": "CAMKL family protein kinase; LKB subfamily protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279629)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, leading to promote their activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0031098 stress-activated protein kinase signaling cascade;GO:1901263 positive regulation of sorocarp spore cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54WJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WN7-1", "uniprot_id": [ { "id": "BZPF_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WN7", "type": "external" } ], "mass": 70777.0, "length": 631, "protein_name": "Probable basic-leucine zipper transcription factor F", "gene_name": "bzpF", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641680", "type": "external" } ], "gene_names_uniprotkb": "bzpF; DDB_G0279529", "gene_names_refseq": "bzpF", "protein_names_uniprotkb": "Probable basic-leucine zipper transcription factor F", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279529)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16410410", "class_list": "", "function": "Probable transcriptional regulator., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0035497 cAMP response element binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0031154 culmination involved in sorocarp development;GO:0031156 regulation of sorocarp development;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54WN7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WR4-1", "uniprot_id": [ { "id": "PLDB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WR4", "type": "external" } ], "mass": 140700.0, "length": 1216, "protein_name": "Phospholipase D B", "gene_name": "pldB", "organism": "Cellular slime mold", "refseq_name": "phospholipase D1", "refseq_ac": [ { "id": "XP_641653", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641653", "type": "external" } ], "gene_names_uniprotkb": "pldB; DDB_G0279483; pld1", "gene_names_refseq": "pldB", "protein_names_uniprotkb": "Phospholipase D B; 3.1.4.4; PLD 1; Phosphatase D1", "protein_names_refseq": "phospholipase D1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279483); (R-DDI-1483166); (R-DDI-2029485); (R-DDI-6798695); (R-DDI-9013149); (R-DDI-9013404)", "pathway_count": 6, "publication_count": 8, "publication_id_list": "15225639;15769249;15821129;15875012;16762450;18164290;6498208;8394342", "class_list": "", "function": "Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. Plays an important role in cell migration by localizing along the anterior cell membrane. Overexpression leads to the inability to aggregate even at higher cell density. Also known as a negative regulator of quorum sensing., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0004630 phospholipase D activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005938 cell cortex;GO:0016020 membrane;GO:0031410 cytoplasmic vesicle;GO:0031982 vesicle;GO:0031143 pseudopodium", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0009395 phospholipid catabolic process;GO:0048870 cell motility;GO:0006644 phospholipid metabolic process;GO:0010467 gene expression", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q54WR4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WS5-1", "uniprot_id": [ { "id": "ROCO6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WS5", "type": "external" } ], "mass": 239183.0, "length": 2147, "protein_name": "Probable serine/threonine-protein kinase roco6", "gene_name": "roco6", "organism": "Cellular slime mold", "refseq_name": "ROCO family protein kinase", "refseq_ac": [ { "id": "XP_641642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641642", "type": "external" } ], "gene_names_uniprotkb": "roco6; DDB_G0279417", "gene_names_refseq": "roco6", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase roco6; 2.7.11.1; Ras of complex proteins and C-terminal of roc 6", "protein_names_refseq": "ROCO family protein kinase; leucine-rich repeat-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279417); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "14654223;15875012", "class_list": "", "function": "May act as a serine/threonine-protein kinase and guanine-nucleotide releasing factor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6XHB0", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54WS5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WT8-1", "uniprot_id": [ { "id": "AQPB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WT8", "type": "external" } ], "mass": 31243.0, "length": 294, "protein_name": "Aquaporin-B", "gene_name": "aqpB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641629", "type": "external" } ], "gene_names_uniprotkb": "aqpB; DDB_G0279443", "gene_names_refseq": "", "protein_names_uniprotkb": "Aquaporin-B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279443); (R-DDI-432047)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;22262860", "class_list": "", "function": "Putatively gated water-specific channel, requiring a cysteine residue within the channel. Impermeable to water, glycerol and urea when expressed in Xenopus oocytes. Not regulated by pH; channels remain impermeable to water at pH 7.4 and 5.2., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0048870 cell motility;GO:0006833 water transport;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54WT8-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0100000000000.100.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WU6-1", "uniprot_id": [ { "id": "SESN_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WU6", "type": "external" } ], "mass": 68407.0, "length": 601, "protein_name": "Sestrin homolog", "gene_name": "DDB_G0279427", "organism": "Cellular slime mold", "refseq_name": "sestrin-like protein", "refseq_ac": [ { "id": "XP_641621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641621", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0279427", "gene_names_refseq": "", "protein_names_uniprotkb": "Sestrin homolog", "protein_names_refseq": "sestrin-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279427); (R-DDI-5628897); (R-DDI-9639288); (R-DDI-9755511)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May function as a negative feedback regulator of TOR function., [UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016684 oxidoreductase activity, acting on peroxide as acceptor;GO:0070728 L-leucine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:1904630 cellular response to diterpene;GO:0010629 negative regulation of gene expression;GO:0032007 negative regulation of TOR signaling;GO:0016239 positive regulation of macroautophagy;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54WU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WX4-1", "uniprot_id": [ { "id": "AURK_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WX4", "type": "external" } ], "mass": 42918.0, "length": 384, "protein_name": "Aurora kinase", "gene_name": "aurK", "organism": "Cellular slime mold", "refseq_name": "Aurora family protein kinase", "refseq_ac": [ { "id": "XP_641803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641803", "type": "external" } ], "gene_names_uniprotkb": "aurK; AurB; Aurora; DDB_G0279343", "gene_names_refseq": "aurK", "protein_names_uniprotkb": "Aurora kinase; 2.7.11.1", "protein_names_refseq": "Aurora family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279343); (R-DDI-174178); (R-DDI-8854050)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15875012;16339076;18326585", "class_list": "", "function": "Part of a chromosomal passenger complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007052 mitotic spindle organization;GO:0032465 regulation of cytokinesis;GO:0051642 centrosome localization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54WX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54WZ2-1", "uniprot_id": [ { "id": "VACB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54WZ2", "type": "external" } ], "mass": 66211.0, "length": 592, "protein_name": "Vacuolin-B", "gene_name": "vacB", "organism": "Cellular slime mold", "refseq_name": "prohibitin domain-containing protein", "refseq_ac": [ { "id": "XP_641785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641785", "type": "external" } ], "gene_names_uniprotkb": "vacB; 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DDB_G0279151", "gene_names_refseq": "cenB", "protein_names_uniprotkb": "Centrin-B; DdCen", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279151); (R-DDI-5696394); (R-DDI-5696395); (R-DDI-9646399)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Plays a fundamental role in microtubule-organizing center structure and function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0000281 mitotic cytokinesis;GO:0007020 microtubule nucleation;GO:0000226 microtubule cytoskeleton organization;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54X77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54X82-1", "uniprot_id": [ { "id": "AP1B_DICDI", "url": "https://www.uniprot.org/uniprot/Q54X82", "type": "external" } ], "mass": 106609.0, "length": 942, "protein_name": "AP-1 complex subunit beta", "gene_name": "ap1b1", "organism": "Cellular slime mold", "refseq_name": "adaptor-related protein complex 1, beta 1 subunit", "refseq_ac": [ { "id": "XP_641846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641846", "type": "external" } ], "gene_names_uniprotkb": "ap1b1; DDB_G0279141", "gene_names_refseq": "ap1b1", "protein_names_uniprotkb": "AP-1 complex subunit beta; Adaptor protein complex AP-1 subunit beta; Adaptor-related protein complex 1 subunit beta; Beta-1-adaptin; Beta-adaptin 1; Clathrin assembly protein complex 1 beta large chain", "protein_names_refseq": "adaptor-related protein complex 1, beta 1 subunit; beta adaptin", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279141); (R-DDI-432720); (R-DDI-437239); (R-DDI-8856825); (R-DDI-8856828); (R-DDI-8866427); (R-DDI-8964038)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030276 clathrin binding", "go_cellular_component": "GO:0030122 AP-2 adaptor complex;GO:0030121 AP-1 adaptor complex;GO:0030132 clathrin coat of coated pit", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0000281 mitotic cytokinesis;GO:0006971 hypotonic response;GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54X82-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XC1-1", "uniprot_id": [ { "id": "5NTC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XC1", "type": "external" } ], "mass": 68352.0, "length": 592, "protein_name": "Cytosolic purine 5'-nucleotidase", "gene_name": "nt5c2", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641940", "type": "external" } ], "gene_names_uniprotkb": "nt5c2; DDB_G0279053", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytosolic purine 5'-nucleotidase; 2.7.1.77; 3.1.3.5; Cytosolic nucleoside phosphotransferase 5'N", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279053); (R-DDI-2161541); (R-DDI-74259); (R-DDI-9755088)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside. Through these activities regulates the purine nucleoside/nucleotide pools within the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "2.7.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.77", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008253 5'-nucleotidase activity;GO:0050146 nucleoside phosphotransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0046054 dGMP metabolic process;GO:0046037 GMP metabolic process;GO:0046040 IMP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54XC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XG7-1", "uniprot_id": [ { "id": "DIMA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XG7", "type": "external" } ], "mass": 140627.0, "length": 1230, "protein_name": "Basic-leucine zipper transcription factor A", "gene_name": "dimA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641883", "type": "external" } ], "gene_names_uniprotkb": "dimA; DDB_G0278971; bzpA", "gene_names_refseq": "dimA", "protein_names_uniprotkb": "Basic-leucine zipper transcription factor A; DIF insensitive mutant A", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278971)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14729573;15875012;16410410", "class_list": "", "function": "Transcriptional regulator involved in DIF-1 signaling. DIF-1 (Differentiation Inducing Factor-1) is a signal molecule involved in the differentiation of pstO (prestalk-O) cells. Functions both as an activator of prestalk gene expression and a repressor of prespore gene expression., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q6T872", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0042802 identical protein binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006935 chemotaxis;GO:0030154 cell differentiation;GO:0045595 regulation of cell differentiation;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54XG7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XI2-1", "uniprot_id": [ { "id": "Q54XI2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XI2", "type": "external" } ], "mass": 107223.0, "length": 938, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "adprt1A", "organism": "Cellular slime mold", "refseq_name": "NAD+ ADP-ribosyltransferase", "refseq_ac": [ { "id": "XP_647821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647821", "type": "external" } ], "gene_names_uniprotkb": "adprt1A; DDB_G0278741", "gene_names_refseq": "adprt1A", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "NAD+ ADP-ribosyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278741); (R-DDI-110362); (R-DDI-3108214); (R-DDI-5696394); (R-DDI-5696395)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "3.2.1.143", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.143", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0010628 positive regulation of gene expression;GO:0007346 regulation of mitotic cell cycle;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54XI2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XL6-1", "uniprot_id": [ { "id": "FRAY1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XL6", "type": "external" } ], "mass": 64223.0, "length": 574, "protein_name": "Serine/threonine-protein kinase fray1", "gene_name": "fray1", "organism": "Cellular slime mold", "refseq_name": "FRAY subfamily protein kinase", "refseq_ac": [ { "id": "XP_647787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647787", "type": "external" } ], "gene_names_uniprotkb": "fray1; DDB_G0278863", "gene_names_refseq": "fray1", "protein_names_uniprotkb": "Serine/threonine-protein kinase fray1; 2.7.11.1; STE20-like kinase fray1", "protein_names_refseq": "FRAY subfamily protein kinase; STE20 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278863); (R-DDI-380972)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;16842885", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:1902554 serine/threonine protein kinase complex", "go_biological_process": "GO:0006611 protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54XL6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XP1-1", "uniprot_id": [ { "id": "Y8823_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XP1", "type": "external" } ], "mass": 41418.0, "length": 356, "protein_name": "Probable farnesyl diphosphate synthase DDB_G0278823", "gene_name": "DDB_G0278823", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641989", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0278823", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable farnesyl diphosphate synthase DDB_G0278823; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.10; 2.5.1.1; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Geranyltranstransferase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278823)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a sterol precursor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.1", "type": "external" }, { "id": "2.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.10", "type": "external" }, { "id": "2.5.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.29", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0004161 dimethylallyltranstransferase activity;GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0033384 geranyl diphosphate biosynthetic process;GO:0045337 farnesyl diphosphate biosynthetic process;GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54XP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XQ2-1", "uniprot_id": [ { "id": "RCKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XQ2", "type": "external" } ], "mass": 125492.0, "length": 1125, "protein_name": "RGS domain-containing serine/threonine-protein kinase A", "gene_name": "rckA", "organism": "Cellular slime mold", "refseq_name": "RGS domain-containing protein", "refseq_ac": [ { "id": "XP_641978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641978", "type": "external" } ], "gene_names_uniprotkb": "rckA; DDB_G0278737; rck1", "gene_names_refseq": "rckA", "protein_names_uniprotkb": "RGS domain-containing serine/threonine-protein kinase A; 2.7.11.1; RGS domain-containing serine/threonine-protein kinase 1", "protein_names_refseq": "RGS domain-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278737)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12686622;15875012;16596165", "class_list": "", "function": "Serine/threonine kinase involved in negative regulation of chemotaxis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8I811", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0007165 signal transduction;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0050921 positive regulation of chemotaxis;GO:0061123 negative regulation of positive chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54XQ2-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XS1-1", "uniprot_id": [ { "id": "PH4H_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XS1", "type": "external" } ], "mass": 50415.0, "length": 441, "protein_name": "Phenylalanine-4-hydroxylase", "gene_name": "pah", "organism": "Cellular slime mold", "refseq_name": "phenylalanine 4-monooxygenase", "refseq_ac": [ { "id": "XP_641959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641959", "type": "external" } ], "gene_names_uniprotkb": "pah; DDB_G0278781", "gene_names_refseq": "pah", "protein_names_uniprotkb": "Phenylalanine-4-hydroxylase; 1.14.16.1; 1.14.16.4; PAH; Phe-4-monooxygenase; TRH; Tryptophan 5-hydroxylase; Tryptophan 5-monooxygenase", "protein_names_refseq": "phenylalanine 4-monooxygenase; phenylalanine hydroxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278781); (R-DDI-209905); (R-DDI-209931); (R-DDI-8964208)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "15875012;18835579", "class_list": "", "function": "Catalyzes the hydroxylation of L-phenylalanine (PubMed:18835579). Hydroxylates L-tryptophan to 5-hydroxy-L-tryptophan but does not hydroxylate L-tyrosine to L-DOPA (PubMed:18835579). It uses D-threo-tetrahydrodictyopterin (DH4), also known as dictyoperin, as a cofactor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.16.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.1", "type": "external" }, { "id": "1.14.16.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.4", "type": "external" } ], "go_molecular_function": "GO:0034617 tetrahydrobiopterin binding;GO:0004510 tryptophan 5-monooxygenase activity;GO:0005506 iron ion binding;GO:0042802 identical protein binding;GO:0004497 monooxygenase activity", "go_cellular_component": "", "go_biological_process": "GO:0006571 tyrosine biosynthetic process;GO:0006559 L-phenylalanine catabolic process;GO:0009094 L-phenylalanine biosynthetic process;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54XS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XS3-1", "uniprot_id": [ { "id": "GDT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XS3", "type": "external" } ], "mass": 186642.0, "length": 1661, "protein_name": "Probable inactive serine/threonine-protein kinase gdt1", "gene_name": "gdt1", "organism": "Cellular slime mold", "refseq_name": "GDT family protein kinase", "refseq_ac": [ { "id": "XP_641957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641957", "type": "external" } ], "gene_names_uniprotkb": "gdt1; DDB_G0278723", "gene_names_refseq": "gdt1", "protein_names_uniprotkb": "Probable inactive serine/threonine-protein kinase gdt1; Growth-differentiation transition protein 1", "protein_names_refseq": "GDT family protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278723)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10793140;15236669;15875012", "class_list": "", "function": "Regulates the transition between growth and differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9GRX5;Q9U987", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0051093 negative regulation of developmental process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54XS3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XV3-1", "uniprot_id": [ { "id": "NEDD8_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XV3", "type": "external" } ], "mass": 8515.0, "length": 77, "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "nedd8", "organism": "Cellular slime mold", "refseq_name": "ubiquitin-like protein Nedd8", "refseq_ac": [ { "id": "XP_642449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642449", "type": "external" } ], "gene_names_uniprotkb": "nedd8; DDB_G0278711", "gene_names_refseq": "nedd8", "protein_names_uniprotkb": "Ubiquitin-like protein NEDD8; Neddylin", "protein_names_refseq": "ubiquitin-like protein Nedd8", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278711); (R-DDI-5689603); (R-DDI-8856825); (R-DDI-8951664); (R-DDI-917937)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Ubiquitin-like protein which plays an important role in cell cycle control. Attachment of nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0097602 cullin family protein binding;GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0008283 cell population proliferation;GO:0030162 regulation of proteolysis;GO:0031647 regulation of protein stability;GO:0019941 modification-dependent protein catabolic process;GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54XV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XY1-1", "uniprot_id": [ { "id": "Q54XY1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XY1", "type": "external" } ], "mass": 43535.0, "length": 386, "protein_name": "Patatin family protein", "gene_name": "plaA", "organism": "Cellular slime mold", "refseq_name": "calcium-independent PLA2", "refseq_ac": [ { "id": "XP_642421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642421", "type": "external" } ], "gene_names_uniprotkb": "plaA; DDB_G0278525", "gene_names_refseq": "plaA", "protein_names_uniprotkb": "Patatin family protein", "protein_names_refseq": "calcium-independent PLA2; patatin family protein; phospholipase A2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278525)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0031252 cell leading edge", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0031000 response to caffeine;GO:0050920 regulation of chemotaxis;GO:0050918 positive chemotaxis;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54XY1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54XY4-1", "uniprot_id": [ { "id": "SCAA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54XY4", "type": "external" } ], "mass": 174927.0, "length": 1582, "protein_name": "Sca1 complex scaffold protein scaA", "gene_name": "scaA", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "scaA; D1105; DDB0220018; DDB_G0277843; sca1", "gene_names_refseq": "", "protein_names_uniprotkb": "Sca1 complex scaffold protein scaA", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277843)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;20493808", "class_list": "", "function": "Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808). The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808). ScaA acts as a molecular scaffold, bringing together gefA, gefH and phr with PP2A (PubMed:20493808)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031252 cell leading edge;GO:1905742 Ras guanyl-nucleotide exchange factor complex", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:1904515 positive regulation of TORC2 signaling;GO:0030587 sorocarp development;GO:0031152 aggregation involved in sorocarp development;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54XY4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Y08-1", "uniprot_id": [ { "id": "NGAP_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Y08", "type": "external" } ], "mass": 98378.0, "length": 877, "protein_name": "Probable Ras GTPase-activating-like protein ngap", "gene_name": "ngap", "organism": "Cellular slime mold", "refseq_name": "C2 domain-containing protein", "refseq_ac": [ { "id": "XP_642394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642394", "type": "external" } ], "gene_names_uniprotkb": "ngap; DDB_G0278483", "gene_names_refseq": "ngap", "protein_names_uniprotkb": "Probable Ras GTPase-activating-like protein ngap; DdNGAP", "protein_names_refseq": "C2 domain-containing protein; NGAP-like protein; Ras p21 protein activator; RasGTPase-activating protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278483); (R-DDI-5218921); (R-DDI-5658442); (R-DDI-8849471)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "15875012;18590548", "class_list": "", "function": "May function as a Ras GTPase-activating protein., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0031256 leading edge membrane", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0051592 response to calcium ion;GO:0030334 regulation of cell migration;GO:0008360 regulation of cell shape;GO:1902531 regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54Y08-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Y26-1", "uniprot_id": [ { "id": "NDRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Y26", "type": "external" } ], "mass": 61021.0, "length": 530, "protein_name": "Probable serine/threonine-protein kinase ndrA", "gene_name": "ndrA", "organism": "Cellular slime mold", "refseq_name": "NDR family protein kinase", "refseq_ac": [ { "id": "XP_642376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642376", "type": "external" } ], "gene_names_uniprotkb": "ndrA; DDB_G0278457", "gene_names_refseq": "ndrA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase ndrA; 2.7.11.1; Nuclear DBF2-related kinase A", "protein_names_refseq": "NDR family protein kinase; protein kinase, AGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278457); (R-DDI-2028269)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0072686 mitotic spindle", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0060100 positive regulation of phagocytosis, engulfment", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Y26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Y32-1", "uniprot_id": [ { "id": "MPL3_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Y32", "type": "external" } ], "mass": 95418.0, "length": 856, "protein_name": "MAP kinase phosphatase with leucine-rich repeats protein 3", "gene_name": "mpl3", "organism": "Cellular slime mold", "refseq_name": "leucine-rich repeat-containing protein", "refseq_ac": [ { "id": "XP_642370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642370", "type": "external" } ], "gene_names_uniprotkb": "mpl3; DDB_G0278445", "gene_names_refseq": "mpl3", "protein_names_uniprotkb": "MAP kinase phosphatase with leucine-rich repeats protein 3; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "leucine-rich repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278445)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Y32-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Y50-1", "uniprot_id": [ { "id": "Q54Y50_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Y50", "type": "external" } ], "mass": 79769.0, "length": 695, "protein_name": "ANTH domain-containing protein", "gene_name": "clmA", "organism": "Cellular slime mold", "refseq_name": "ANTH domain-containing protein", "refseq_ac": [ { "id": "XP_642352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642352", "type": "external" } ], "gene_names_uniprotkb": "clmA; DDB_G0278685", "gene_names_refseq": "clmA", "protein_names_uniprotkb": "ANTH domain-containing protein", "protein_names_refseq": "ANTH domain-containing protein; clathrin assembly protein AP180", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278685); (R-DDI-8856825)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005545 1-phosphatidylinositol binding;GO:0000149 SNARE binding;GO:0032050 clathrin heavy chain binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle;GO:0030131 clathrin adaptor complex;GO:0071439 clathrin complex", "go_biological_process": "GO:0006900 vesicle budding from membrane;GO:0009992 intracellular water homeostasis;GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Y50-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YD9-1", "uniprot_id": [ { "id": "FOL1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YD9", "type": "external" } ], "mass": 73720.0, "length": 657, "protein_name": "Folic acid synthesis protein FOL1", "gene_name": "fol1", "organism": "Cellular slime mold", "refseq_name": "dihydro-6-hydroxymethylpterin pyrophosphokinase", "refseq_ac": [ { "id": "XP_642263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642263", "type": "external" } ], "gene_names_uniprotkb": "fol1; DDB_G0278283", "gene_names_refseq": "fol1", "protein_names_uniprotkb": "Folic acid synthesis protein FOL1; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; 2.7.6.3; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; 7,8-dihydroneopterin aldolase; Dihydropteroate pyrophosphorylase; PPPK", "protein_names_refseq": "dihydro-6-hydroxymethylpterin pyrophosphokinase; dihydroneopterin aldolase domain-containing protein; dihydropteroate synthetase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278283)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes three sequential steps of tetrahydrofolate biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.15", "type": "external" }, { "id": "2.7.6.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.6.3", "type": "external" }, { "id": "4.1.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.25", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016301 kinase activity;GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity;GO:0004150 dihydroneopterin aldolase activity", "go_cellular_component": "GO:0005740 mitochondrial envelope", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0046656 folic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54YD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YF2-1", "uniprot_id": [ { "id": "AMPKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YF2", "type": "external" } ], "mass": 81639.0, "length": 727, "protein_name": "5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha", "gene_name": "snfA", "organism": "Cellular slime mold", "refseq_name": "AMP-activated protein kinase alpha subunit", "refseq_ac": [ { "id": "XP_642250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642250", "type": "external" } ], "gene_names_uniprotkb": "snfA; DDB_G0277905; ampka; prkaa", "gene_names_refseq": "snfA", "protein_names_uniprotkb": "5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha; 2.7.11.1; AMPKA; Protein kinase, AMP-activated, alpha subunit; SNF1/AMP-activated kinase catalytic subunit; Sucrose non-fermenting protein snfA", "protein_names_refseq": "AMP-activated protein kinase alpha subunit; AMPK complex alpha subunit; CAMKL family protein kinase; SNF/AMP-activated kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277905); (R-DDI-1632852); (R-DDI-163680); (R-DDI-200425); (R-DDI-380972); (R-DDI-5628897)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "15875012;17332500", "class_list": "", "function": "Activated enzyme phosphorylates target proteins and initiates downstream signaling pathways that shift metabolism from anabolic to catabolic pathways. Acts as a highly sensitive cellular energy sensor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XYP6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "6.3.4.14", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.14", "type": "external" }, { "id": "6.4.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.2", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004679 AMP-activated protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0030139 endocytic vesicle", "go_biological_process": "GO:1904630 cellular response to diterpene;GO:0006468 protein phosphorylation;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0006754 ATP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54YF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YH4-1", "uniprot_id": [ { "id": "DHKB_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YH4", "type": "external" } ], "mass": 218999.0, "length": 1969, "protein_name": "Hybrid signal transduction histidine kinase B", "gene_name": "dhkB", "organism": "Cellular slime mold", "refseq_name": "HisK family protein kinase", "refseq_ac": [ { "id": "XP_642228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642228", "type": "external" } ], "gene_names_uniprotkb": "dhkB; DDB_G0277845", "gene_names_refseq": "dhkB", "protein_names_uniprotkb": "Hybrid signal transduction histidine kinase B; 2.7.13.3", "protein_names_refseq": "HisK family protein kinase; histidine kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277845)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;18216168;9576830", "class_list": "", "function": "Acts in the cytokinin signal transduction pathway that regulates spore germination. Required for the maintenance of spore dormancy. Does not appear to act as a cytokinin receptor. Probably undergoes ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, which is followed by transfer of the phosphoryl group to a conserved aspartate residue in the receiver domain., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15763", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000155 phosphorelay sensor kinase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:1904359 regulation of spore germination;GO:0009736 cytokinin-activated signaling pathway;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q54YH4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YL2-1", "uniprot_id": [ { "id": "DAK_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YL2", "type": "external" } ], "mass": 28416.0, "length": 245, "protein_name": "Deoxyadenosine kinase", "gene_name": "dak", "organism": "Cellular slime mold", "refseq_name": "deoxyadenosine kinase", "refseq_ac": [ { "id": "XP_642190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642190", "type": "external" } ], "gene_names_uniprotkb": "dak; DDB_G0278191", "gene_names_refseq": "dak", "protein_names_uniprotkb": "Deoxyadenosine kinase; 2.7.1.76; DAK; DddDAK", "protein_names_refseq": "deoxyadenosine kinase; deoxyribonucleoside kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278191); (R-DDI-73614); (R-DDI-74217)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;17448496", "class_list": "", "function": "Specific kinase that phosphorylates deoxyadenosine but not any other deoxyribonucleoside, as part of the deoxyribonucleotide salvage pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q49UB1", "ec_number_list": [ { "id": "2.7.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.76", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019136 deoxynucleoside kinase activity;GO:0004136 deoxyadenosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006139 nucleobase-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54YL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YU6-1", "uniprot_id": [ { "id": "CRTF_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YU6", "type": "external" } ], "mass": 98085.0, "length": 876, "protein_name": "CAR1 transcription factor", "gene_name": "CRTF", "organism": "Cellular slime mold", "refseq_name": "transcription factor", "refseq_ac": [ { "id": "XP_642106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642106", "type": "external" } ], "gene_names_uniprotkb": "CRTF; DDB_G0278077", "gene_names_refseq": "CRTF", "protein_names_uniprotkb": "CAR1 transcription factor; CAR1-binding factor; CRTF", "protein_names_refseq": "transcription factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278077)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11493573;15875012;18590548;9716534", "class_list": "", "function": "Nuclear transcription factor with zinc-dependent sequence binding specificity. Required for carA-1 and carA-2 expression in early development. Also required throughout later developmental stages - where it has a cell-autonomous role that is distinct from its capacity to control carA-1 and carA-2 expression. Required for terminal spore differentiation but not essential for cell differentiation and cell sorting. May function to help insulate distinct pathways from simultaneous and universal activation by cAMP., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010043 response to zinc ion;GO:0043938 positive regulation of sporulation;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q54YU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YV4-1", "uniprot_id": [ { "id": "LONM1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YV4", "type": "external" } ], "mass": 108047.0, "length": 956, "protein_name": "Lon protease homolog, mitochondrial 1", "gene_name": "DDB_G0278063", "organism": "Cellular slime mold", "refseq_name": "peptidase S16, Lon protease family protein", "refseq_ac": [ { "id": "XP_642098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642098", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0278063", "gene_names_refseq": "", "protein_names_uniprotkb": "Lon protease homolog, mitochondrial 1; 3.4.21.53", "protein_names_refseq": "peptidase S16, Lon protease family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278063)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043565 sequence-specific DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0007005 mitochondrion organization;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0051131 chaperone-mediated protein complex assembly;GO:0070407 oxidation-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54YV4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YW1-1", "uniprot_id": [ { "id": "ELMOA_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YW1", "type": "external" } ], "mass": 109938.0, "length": 977, "protein_name": "ELMO domain-containing protein A", "gene_name": "elmoA", "organism": "Cellular slime mold", "refseq_name": "engulfment and cell motility ELM family protein", "refseq_ac": [ { "id": "XP_642091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642091", "type": "external" } ], "gene_names_uniprotkb": "elmoA; DDB_G0278051", "gene_names_refseq": "elmoA", "protein_names_uniprotkb": "ELMO domain-containing protein A", "protein_names_refseq": "engulfment and cell motility ELM family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278051); (R-DDI-8849471)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;18854143", "class_list": "", "function": "Functions as a negative regulator of actin polymerization. Modulates actin/myosin II at cortex actinomyosins to prevent excessive F-actin polymerization around the cell periphery, thereby maintaining proper cell shape during phagocytosis and chemotaxis., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045159 myosin II binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0048870 cell motility;GO:0030837 negative regulation of actin filament polymerization;GO:0050764 regulation of phagocytosis;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54YW1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54YZ0-1", "uniprot_id": [ { "id": "UGPA2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54YZ0", "type": "external" } ], "mass": 56268.0, "length": 502, "protein_name": "UTP--glucose-1-phosphate uridylyltransferase 2", "gene_name": "ugpB", "organism": "Cellular slime mold", "refseq_name": "UDP-glucose pyrophosphorylase 2", "refseq_ac": [ { "id": "XP_642062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642062", "type": "external" } ], "gene_names_uniprotkb": "ugpB; DDB_G0277879", "gene_names_refseq": "ugpB", "protein_names_uniprotkb": "UTP--glucose-1-phosphate uridylyltransferase 2; 2.7.7.9; UDP-glucose pyrophosphorylase 2; UDPGP 2; UGPase 2", "protein_names_refseq": "UDP-glucose pyrophosphorylase 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277879); (R-DDI-173599); (R-DDI-3322077)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12060658;15875012", "class_list": "", "function": "Plays a central role as a glucosyl donor in cellular metabolic pathways., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q27566;Q9XZN2", "ec_number_list": [ { "id": "2.7.7.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.9", "type": "external" } ], "go_molecular_function": "GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031012 extracellular matrix", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0005977 glycogen metabolic process;GO:0006011 UDP-alpha-D-glucose metabolic process;GO:0030244 cellulose biosynthetic process;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54YZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Z25-1", "uniprot_id": [ { "id": "PLDC_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Z25", "type": "external" } ], "mass": 188250.0, "length": 1640, "protein_name": "Phospholipase D C", "gene_name": "pldC", "organism": "Cellular slime mold", "refseq_name": "phospholipase D1", "refseq_ac": [ { "id": "XP_642027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642027", "type": "external" } ], "gene_names_uniprotkb": "pldC; DDB_G0277949; pld1", "gene_names_refseq": "pldC", "protein_names_uniprotkb": "Phospholipase D C; 3.1.4.4; PLD 1; Phosphatase D1", "protein_names_refseq": "phospholipase D1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277949); (R-DDI-1483166); (R-DDI-2029485); (R-DDI-9013149); (R-DDI-9013404)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "15225639;15769249;15875012;16762450;6498208;8394342", "class_list": "", "function": "Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" } ], "go_molecular_function": "GO:0004630 phospholipase D activity", "go_cellular_component": "", "go_biological_process": "GO:0009395 phospholipid catabolic process;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q54Z25-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Z26-1", "uniprot_id": [ { "id": "GLYC1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Z26", "type": "external" } ], "mass": 50688.0, "length": 457, "protein_name": "Serine hydroxymethyltransferase 1", "gene_name": "shmt1", "organism": "Cellular slime mold", "refseq_name": "serine hydroxymethyltransferase", "refseq_ac": [ { "id": "XP_642026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642026", "type": "external" } ], "gene_names_uniprotkb": "shmt1; DDB_G0277947", "gene_names_refseq": "shmt1", "protein_names_uniprotkb": "Serine hydroxymethyltransferase 1; 2.1.2.1; Glycine hydroxymethyltransferase 1; SHMT 1; Serine methylase 1", "protein_names_refseq": "serine hydroxymethyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277947)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16926386", "class_list": "", "function": "Interconversion of serine and glycine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004372 glycine hydroxymethyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0035999 tetrahydrofolate interconversion;GO:0046653 tetrahydrofolate metabolic process;GO:0019264 glycine biosynthetic process from serine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54Z26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Z42-1", "uniprot_id": [ { "id": "Q54Z42_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Z42", "type": "external" } ], "mass": 74905.0, "length": 669, "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "organism": "Cellular slime mold", "refseq_name": "DNA helicase", "refseq_ac": [ { "id": "XP_642006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642006", "type": "external" } ], "gene_names_uniprotkb": "PIF1; DDB_G0277925; pif1", "gene_names_refseq": "pif1", "protein_names_uniprotkb": "ATP-dependent DNA helicase PIF1; 5.6.2.3; DNA 5'-3' helicase PIF1; DNA repair and recombination helicase PIF1", "protein_names_refseq": "DNA helicase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277925)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54Z42-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54Z85-1", "uniprot_id": [ { "id": "RACO_DICDI", "url": "https://www.uniprot.org/uniprot/Q54Z85", "type": "external" } ], "mass": 31731.0, "length": 276, "protein_name": "Rho-related protein racO", "gene_name": "racO", "organism": "Cellular slime mold", "refseq_name": "Rho GTPase", "refseq_ac": [ { "id": "XP_642468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642468", "type": "external" } ], "gene_names_uniprotkb": "racO; DDB_G0277791", "gene_names_refseq": "racO", "protein_names_uniprotkb": "Rho-related protein racO; 3.6.5.2", "protein_names_refseq": "Rho GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277791); (R-DDI-9013423)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0042995 cell projection", "go_biological_process": "GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0009617 response to bacterium;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54Z85-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54ZW0-1", "uniprot_id": [ { "id": "PHG1B_DICDI", "url": "https://www.uniprot.org/uniprot/Q54ZW0", "type": "external" } ], "mass": 68547.0, "length": 587, "protein_name": "Putative phagocytic receptor 1b", "gene_name": "phg1b", "organism": "Cellular slime mold", "refseq_name": "TM9 protein B", "refseq_ac": [ { "id": "XP_642756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642756", "type": "external" } ], "gene_names_uniprotkb": "phg1b; DDB_G0277273; sigC", "gene_names_refseq": "phg1b", "protein_names_uniprotkb": "Putative phagocytic receptor 1b; SrfA-induced gene C protein", "protein_names_refseq": "TM9 protein B", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277273)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12097910;12857872;14665466;15075287;15875012", "class_list": "", "function": "Involved in adhesion and phagocytosis of hydrophilic particles., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54ZV9;Q6TU46;Q7YTA7", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006909 phagocytosis;GO:0072657 protein localization to membrane;GO:0031589 cell-substrate adhesion;GO:0033299 secretion of lysosomal enzymes;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q54ZW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550C8-1", "uniprot_id": [ { "id": "LONM2_DICDI", "url": "https://www.uniprot.org/uniprot/Q550C8", "type": "external" } ], "mass": 93649.0, "length": 836, "protein_name": "Lon protease homolog, mitochondrial 2", "gene_name": "DDB_0217928; DDB_G0277307", "organism": "Cellular slime mold", "refseq_name": "peptidase S16, Lon protease family protein", "refseq_ac": [ { "id": "XP_642688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642688", "type": "external" } ], "gene_names_uniprotkb": "DDB_0217928; DDB_G0277307", "gene_names_refseq": "", "protein_names_uniprotkb": "Lon protease homolog, mitochondrial 2; 3.4.21.53", "protein_names_refseq": "peptidase S16, Lon protease family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277307); (R-DDI-9837999)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "1.3.8.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.-", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.3.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.16", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043565 sequence-specific DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0007005 mitochondrion organization;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0051131 chaperone-mediated protein complex assembly;GO:0070407 oxidation-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q550C8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550D5-1", "uniprot_id": [ { "id": "GTAA_DICDI", "url": "https://www.uniprot.org/uniprot/Q550D5", "type": "external" } ], "mass": 99004.0, "length": 872, "protein_name": "Transcription factor stalky", "gene_name": "stkA", "organism": "Cellular slime mold", "refseq_name": "GATA zinc finger domain-containing protein 1", "refseq_ac": [ { "id": "XP_642681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642681", "type": "external" } ], "gene_names_uniprotkb": "stkA; DDB_G0277147; gatA", "gene_names_refseq": "stkA", "protein_names_uniprotkb": "Transcription factor stalky; GATA zinc finger domain-containing protein 1", "protein_names_refseq": "GATA zinc finger domain-containing protein 1; GATA-binding transcription factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277147)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11100898;12097910;15875012;8898200", "class_list": "", "function": "Probable transcription factor. Seems to act on the expression of the genes culC, culD, rnpA and sigB., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "P90523;Q86AP1", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q550D5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550F6-1", "uniprot_id": [ { "id": "DCX_DICDI", "url": "https://www.uniprot.org/uniprot/Q550F6", "type": "external" } ], "mass": 34321.0, "length": 308, "protein_name": "Protein doublecortin", "gene_name": "dcx", "organism": "Cellular slime mold", "refseq_name": "doublecortin domain-containing protein", "refseq_ac": [ { "id": "XP_642976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642976", "type": "external" } ], "gene_names_uniprotkb": "dcx; DDB_0217917; DDB_G0277115", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein doublecortin; DdDCX", "protein_names_refseq": "doublecortin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277115)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;21034843", "class_list": "", "function": "Has a cytoskeleton-independent function in chemotactic signaling during development., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005874 microtubule;GO:0005815 microtubule organizing center;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0140582 adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q550F6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550K8-1", "uniprot_id": [ { "id": "Y7071_DICDI", "url": "https://www.uniprot.org/uniprot/Q550K8", "type": "external" } ], "mass": 274128.0, "length": 2454, "protein_name": "Probable serine/threonine-protein kinase DDB_G0277071", "gene_name": "DDB_G0277071", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_642924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642924", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0277071", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0277071; 2.7.11.1", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277071)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q86B02", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0033549 MAP kinase phosphatase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0010468 regulation of gene expression;GO:1900424 regulation of defense response to bacterium;GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q550K8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550L8-1", "uniprot_id": [ { "id": "IFKB_DICDI", "url": "https://www.uniprot.org/uniprot/Q550L8", "type": "external" } ], "mass": 151092.0, "length": 1358, "protein_name": "Probable serine/threonine-protein kinase ifkB", "gene_name": "ifkB", "organism": "Cellular slime mold", "refseq_name": "GCN2 subfamily protein kinase", "refseq_ac": [ { "id": "XP_642914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642914", "type": "external" } ], "gene_names_uniprotkb": "ifkB; DDB_G0276829", "gene_names_refseq": "ifkB", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase ifkB; 2.7.11.1; Initiation factor kinase B", "protein_names_refseq": "GCN2 subfamily protein kinase; PEK family protein kinase; anticodon-binding domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276829)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;12697064;15875012;17177855", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7KWM3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0098609 cell-cell adhesion;GO:0031589 cell-substrate adhesion;GO:0034198 cellular response to amino acid starvation;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q550L8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550Q4-1", "uniprot_id": [ { "id": "RHEB_DICDI", "url": "https://www.uniprot.org/uniprot/Q550Q4", "type": "external" } ], "mass": 20715.0, "length": 185, "protein_name": "GTP-binding protein Rheb homolog", "gene_name": "rheb", "organism": "Cellular slime mold", "refseq_name": "Ras GTPase", "refseq_ac": [ { "id": "XP_642878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642878", "type": "external" } ], "gene_names_uniprotkb": "rheb; DDB_G0277041", "gene_names_refseq": "rheb", "protein_names_uniprotkb": "GTP-binding protein Rheb homolog; 3.6.5.-", "protein_names_refseq": "Ras GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277041); (R-DDI-1632852); (R-DDI-165159); (R-DDI-166208); (R-DDI-380972); (R-DDI-5628897); (R-DDI-8943724); (R-DDI-9639288)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Binds GTP and exhibits intrinsic GTPase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7KWW6", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0005776 autophagosome", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0032008 positive regulation of TOR signaling;GO:0050765 negative regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q550Q4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q550R2-1", "uniprot_id": [ { "id": "CTXB_DICDI", "url": "https://www.uniprot.org/uniprot/Q550R2", "type": "external" } ], "mass": 50460.0, "length": 441, "protein_name": "Cortexillin-2", "gene_name": "ctxB", "organism": "Cellular slime mold", "refseq_name": "cortexillin II", "refseq_ac": [ { "id": "XP_642870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642870", "type": "external" } ], "gene_names_uniprotkb": "ctxB; DDB_G0276893", "gene_names_refseq": "ctxB", "protein_names_uniprotkb": "Cortexillin-2; Cortexillin II", "protein_names_refseq": "cortexillin II", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276893)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;8752217", "class_list": "", "function": "Actin-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15814;Q8MNG7", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0019887 protein kinase regulator activity;GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0031252 cell leading edge;GO:0032154 cleavage furrow;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0000902 cell morphogenesis;GO:0030036 actin cytoskeleton organization;GO:0030866 cortical actin cytoskeleton organization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q550R2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q551H4-1", "uniprot_id": [ { "id": "FRAY2_DICDI", "url": "https://www.uniprot.org/uniprot/Q551H4", "type": "external" } ], "mass": 115488.0, "length": 1028, "protein_name": "Serine/threonine-protein kinase fray2", "gene_name": "fray2", "organism": "Cellular slime mold", "refseq_name": "FRAY subfamily protein kinase", "refseq_ac": [ { "id": "XP_643160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643160", "type": "external" } ], "gene_names_uniprotkb": "fray2; DDB_G0229911", "gene_names_refseq": "fray2", "protein_names_uniprotkb": "Serine/threonine-protein kinase fray2; 2.7.11.1; STE20-like kinase fray2", "protein_names_refseq": "FRAY subfamily protein kinase; STE20 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276577); (R-DDI-380972)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;16842885", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q869U1", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:1902554 serine/threonine protein kinase complex", "go_biological_process": "GO:0006611 protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q551H4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q551M2-1", "uniprot_id": [ { "id": "IF6_DICDI", "url": "https://www.uniprot.org/uniprot/Q551M2", "type": "external" } ], "mass": 26254.0, "length": 244, "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "eif6", "organism": "Cellular slime mold", "refseq_name": "eukaryotic translation initiation factor 6", "refseq_ac": [ { "id": "XP_643108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643108", "type": "external" } ], "gene_names_uniprotkb": "eif6; DDB_G0276493", "gene_names_refseq": "eIF6", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 6; eIF-6", "protein_names_refseq": "eukaryotic translation initiation factor 6", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276493)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000054 ribosomal subunit export from nucleus;GO:0000460 maturation of 5.8S rRNA;GO:0042256 cytosolic ribosome assembly;GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q551M2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q551V8-1", "uniprot_id": [ { "id": "Q551V8_DICDI", "url": "https://www.uniprot.org/uniprot/Q551V8", "type": "external" } ], "mass": 315318.0, "length": 2843, "protein_name": "Guanylyl cyclase", "gene_name": "sgcA", "organism": "Cellular slime mold", "refseq_name": "guanylyl cyclase", "refseq_ac": [ { "id": "XP_643219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643219", "type": "external" } ], "gene_names_uniprotkb": "sgcA; DDB_G0276269", "gene_names_refseq": "sgcA", "protein_names_uniprotkb": "Guanylyl cyclase", "protein_names_refseq": "guanylyl cyclase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276269)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004383 guanylate cyclase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0031252 cell leading edge;GO:1904269 cell leading edge cell cortex", "go_biological_process": "GO:0006935 chemotaxis;GO:0035556 intracellular signal transduction;GO:0051602 response to electrical stimulus;GO:0050920 regulation of chemotaxis;GO:0031033 myosin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q551V8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q552C6-1", "uniprot_id": [ { "id": "ZAK2_DICDI", "url": "https://www.uniprot.org/uniprot/Q552C6", "type": "external" } ], "mass": 72979.0, "length": 635, "protein_name": "Dual specificity protein kinase zak2", "gene_name": "zak2", "organism": "Cellular slime mold", "refseq_name": "CZAK family protein kinase", "refseq_ac": [ { "id": "XP_643302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643302", "type": "external" } ], "gene_names_uniprotkb": "zak2; DDB_G0276187; DpyK4; pyk4", "gene_names_refseq": "pyk4", "protein_names_uniprotkb": "Dual specificity protein kinase zak2; 2.7.12.1; Tyrosine-protein kinase 4; Zaphod K Kinase 2; Zaphod kinase 2", "protein_names_refseq": "CZAK family protein kinase; NZAK subfamily protein kinase; protein kinase, STE group; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276187); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 4, "publication_id_list": "12097910;15875012;21205787;8898113", "class_list": "", "function": "Positive regulator of gsk3/gskA activity required for cell pattern formation and a downstream effector of carC. The kinases, gsk3/gskA, zakA and zak2, form part of a signaling pathway that responds to extracellular cyclic AMP. The pathway has a role in transcriptional regulation; required to direct prespore/spore fates during development. Zak2 negatively regulates prestalk differentiation by regulating expression of ecmA. Phosphorylates Y-214 of gsk3/gskA, in vitro., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q75JK1", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0010468 regulation of gene expression;GO:0042659 regulation of cell fate specification;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q552C6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q552D9-1", "uniprot_id": [ { "id": "SMC3_DICDI", "url": "https://www.uniprot.org/uniprot/Q552D9", "type": "external" } ], "mass": 164847.0, "length": 1437, "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "smc3", "organism": "Cellular slime mold", "refseq_name": "structural maintenance of chromosome protein", "refseq_ac": [ { "id": "XP_643274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643274", "type": "external" } ], "gene_names_uniprotkb": "smc3; DDB_G0276101", "gene_names_refseq": "smc3", "protein_names_uniprotkb": "Structural maintenance of chromosomes protein 3; SMC protein 3; SMC-3", "protein_names_refseq": "structural maintenance of chromosome protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276101); (R-DDI-2468052); (R-DDI-2470946); (R-DDI-2500257); (R-DDI-3108214)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Central component of cohesin, a complex which is required for the cohesion of sister chromatids after DNA replication. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. Involved in chromosome cohesion during the cell cycle and in DNA repair it also regulates DNA replication. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosomes movement (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q75JI4", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046982 protein heterodimerization activity;GO:0016887 ATP hydrolysis activity;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0030892 mitotic cohesin complex;GO:0005634 nucleus;GO:0000785 chromatin;GO:0008278 cohesin complex", "go_biological_process": "GO:0051301 cell division;GO:0006275 regulation of DNA replication;GO:0007064 mitotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q552D9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q552E2-1", "uniprot_id": [ { "id": "WASC2_DICDI", "url": "https://www.uniprot.org/uniprot/Q552E2", "type": "external" } ], "mass": 160367.0, "length": 1479, "protein_name": "WASH complex subunit 2", "gene_name": "washc2", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643271", "type": "external" } ], "gene_names_uniprotkb": "washc2; DDB_G0276221; fam21", "gene_names_refseq": "", "protein_names_uniprotkb": "WASH complex subunit 2", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276221)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q75JI1", "ec_number_list": [], "go_molecular_function": "GO:1901981 phosphatidylinositol phosphate binding;GO:1905394 retromer complex binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0071203 WASH complex;GO:0061474 phagolysosome membrane", "go_biological_process": "GO:0036010 protein localization to endosome;GO:0042147 retrograde transport, endosome to Golgi;GO:0030837 negative regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q552E2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q552S0-1", "uniprot_id": [ { "id": "NHE1_DICDI", "url": "https://www.uniprot.org/uniprot/Q552S0", "type": "external" } ], "mass": 75521.0, "length": 674, "protein_name": "Sodium/hydrogen exchanger 1", "gene_name": "nhe1", "organism": "Cellular slime mold", "refseq_name": "Na-H exchanger", "refseq_ac": [ { "id": "XP_643611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643611", "type": "external" } ], "gene_names_uniprotkb": "nhe1; DDB_G0275711", "gene_names_refseq": "nhe1", "protein_names_uniprotkb": "Sodium/hydrogen exchanger 1; DdNHE1; NHE1; Na-H exchanger 1", "protein_names_refseq": "Na-H exchanger; sodium/hydrogen exchanger", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275711); (R-DDI-425986)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "12097910;15851518;15875012;18590548", "class_list": "", "function": "Regulation of intracellular pH homeostasis in response to cAMP, which is essential for chemotaxis. Necessary for F-actin localization and the kinetics of actin polymerization during chemotaxis and cell polarity but not for directional sensing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86IB9", "ec_number_list": [], "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031252 cell leading edge;GO:0031256 leading edge membrane", "go_biological_process": "GO:0006935 chemotaxis;GO:0019722 calcium-mediated signaling;GO:0051592 response to calcium ion;GO:0006909 phagocytosis;GO:0003365 establishment of cell polarity involved in ameboidal cell migration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q552S0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553K4-1", "uniprot_id": [ { "id": "NRAM2_DICDI", "url": "https://www.uniprot.org/uniprot/Q553K4", "type": "external" } ], "mass": 70404.0, "length": 629, "protein_name": "Natural resistance-associated macrophage protein 2 homolog", "gene_name": "nramp2", "organism": "Cellular slime mold", "refseq_name": "natural resistance-associated macrophage protein", "refseq_ac": [ { "id": "XP_643409", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643409", "type": "external" } ], "gene_names_uniprotkb": "nramp2; DDB_G0275815; mntH; nrampB", "gene_names_refseq": "", "protein_names_uniprotkb": "Natural resistance-associated macrophage protein 2 homolog", "protein_names_refseq": "natural resistance-associated macrophage protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275815)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12097910;15875012;22992462;26208637;27528008;28680861", "class_list": "", "function": "Transports Fe(2+) in a non-electrogenic and proton-independent manner (PubMed:26208637). Required for resistance to pathogenic bacteria, such as Legionella pneumophila and Francisella noatunensis subsp. noatunensis (PubMed:22992462, PubMed:28680861)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q86H95", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005384 manganese ion transmembrane transporter activity;GO:0015093 ferrous iron transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0034755 iron ion transmembrane transport;GO:1903988 iron ion export across plasma membrane;GO:0006879 intracellular iron ion homeostasis;GO:0009617 response to bacterium;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q553K4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553P5-1", "uniprot_id": [ { "id": "STX8A_DICDI", "url": "https://www.uniprot.org/uniprot/Q553P5", "type": "external" } ], "mass": 17204.0, "length": 152, "protein_name": "Syntaxin-8A", "gene_name": "syn8A", "organism": "Cellular slime mold", "refseq_name": "syntaxin 8", "refseq_ac": [ { "id": "XP_643701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643701", "type": "external" } ], "gene_names_uniprotkb": "syn8A; DDB_G0275429; syn8", "gene_names_refseq": "syn8A", "protein_names_uniprotkb": "Syntaxin-8A", "protein_names_refseq": "syntaxin 8; t-SNARE family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275429)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;12175335;15875012", "class_list": "", "function": "Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for fusion of late endosomes with lysosomes and homotypic lysosomal fusion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0010008 endosome membrane;GO:0031201 SNARE complex", "go_biological_process": "GO:0008333 endosome to lysosome transport;GO:0006906 vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q553P5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553U6-1", "uniprot_id": [ { "id": "ACT22_DICDI", "url": "https://www.uniprot.org/uniprot/Q553U6", "type": "external" } ], "mass": 41735.0, "length": 376, "protein_name": "Putative actin-22", "gene_name": "act22", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643865", "type": "external" } ], "gene_names_uniprotkb": "act22; DDB_G0275023", "gene_names_refseq": "act22", "protein_names_uniprotkb": "Putative actin-22; 3.6.4.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275023); (R-DDI-114608); (R-DDI-2029482); (R-DDI-5626467); (R-DDI-5663213); (R-DDI-9013418); (R-DDI-9953170)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q869Z2", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0017022 myosin binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005911 cell-cell junction;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0006909 phagocytosis;GO:0000902 cell morphogenesis;GO:0051591 response to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q553U6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553W9-1", "uniprot_id": [ { "id": "CLN5_DICDI", "url": "https://www.uniprot.org/uniprot/Q553W9", "type": "external" } ], "mass": 37282.0, "length": 322, "protein_name": "Ceroid-lipofuscinosis neuronal protein 5 homolog", "gene_name": "cln5", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643842", "type": "external" } ], "gene_names_uniprotkb": "cln5; DDB_G0275299", "gene_names_refseq": "cln5", "protein_names_uniprotkb": "Ceroid-lipofuscinosis neuronal protein 5 homolog; Protein CLN5", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275299)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q86I57;Q86I58", "ec_number_list": [], "go_molecular_function": "GO:0016798 hydrolase activity, acting on glycosyl bonds", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005938 cell cortex;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0006914 autophagy;GO:0007040 lysosome organization;GO:0009306 protein secretion;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q553W9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553X7-1", "uniprot_id": [ { "id": "GALE_DICDI", "url": "https://www.uniprot.org/uniprot/Q553X7", "type": "external" } ], "mass": 37850.0, "length": 344, "protein_name": "UDP-glucose 4-epimerase", "gene_name": "galE", "organism": "Cellular slime mold", "refseq_name": "UDP-glucose 4-epimerase", "refseq_ac": [ { "id": "XP_643834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643834", "type": "external" } ], "gene_names_uniprotkb": "galE; DDB_G0275295", "gene_names_refseq": "galE", "protein_names_uniprotkb": "UDP-glucose 4-epimerase; 5.1.3.2; 5.1.3.7; Galactowaldenase; UDP-GalNAc 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-galactosamine 4-epimerase; UDP-galactose 4-epimerase", "protein_names_refseq": "UDP-glucose 4-epimerase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275295); (R-DDI-70370)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;4252223", "class_list": "", "function": "Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86I53", "ec_number_list": [ { "id": "5.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.2", "type": "external" }, { "id": "5.1.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.7", "type": "external" } ], "go_molecular_function": "GO:0003978 UDP-glucose 4-epimerase activity;GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0005996 monosaccharide metabolic process;GO:0006012 galactose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q553X7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553Y0-1", "uniprot_id": [ { "id": "P2XC_DICDI", "url": "https://www.uniprot.org/uniprot/Q553Y0", "type": "external" } ], "mass": 41756.0, "length": 368, "protein_name": "P2X receptor C", "gene_name": "p2xC", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643831", "type": "external" } ], "gene_names_uniprotkb": "p2xC; DDB_G0275191", "gene_names_refseq": "p2xC", "protein_names_uniprotkb": "P2X receptor C; P2XC", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275191); (R-DDI-139853); (R-DDI-418346); (R-DDI-6798695); (R-DDI-844456)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "12097910;15875012;19833731", "class_list": "", "function": "P2X receptors are ligand-gated ion channels that play a role in intracellular calcium signaling. ATP does not evoke inward currents in p2xC. Not essential for osmoregulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035381 ATP-gated ion channel activity;GO:0140417 intracellularly ATP-gated calcium channel activity", "go_cellular_component": "GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0070588 calcium ion transmembrane transport;GO:0050848 regulation of calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q553Y0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553Y1-1", "uniprot_id": [ { "id": "P2XB_DICDI", "url": "https://www.uniprot.org/uniprot/Q553Y1", "type": "external" } ], "mass": 41871.0, "length": 369, "protein_name": "P2X receptor B", "gene_name": "p2xB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643830", "type": "external" } ], "gene_names_uniprotkb": "p2xB; DDB_G0275293", "gene_names_refseq": "p2xB", "protein_names_uniprotkb": "P2X receptor B; P2XB", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275293); (R-DDI-139853); (R-DDI-418346); (R-DDI-6798695); (R-DDI-844456)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "12097910;15875012;19833731", "class_list": "", "function": "P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Not essential for osmoregulation. Inward currents are evoked by intracellular ATP and ATP analogs. Insensitive to the P2 receptor antagonists PPADS and suramin, and also copper ions. Inhibited by sodium ions. Permeable to chloride ions., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0035381 ATP-gated ion channel activity;GO:0140417 intracellularly ATP-gated calcium channel activity", "go_cellular_component": "GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0006811 monoatomic ion transport;GO:0070588 calcium ion transmembrane transport;GO:0050848 regulation of calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q553Y1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q553Y7-1", "uniprot_id": [ { "id": "GCA_DICDI", "url": "https://www.uniprot.org/uniprot/Q553Y7", "type": "external" } ], "mass": 167362.0, "length": 1483, "protein_name": "Guanylyl cyclase, membrane", "gene_name": "gca", "organism": "Cellular slime mold", "refseq_name": "guanylyl cyclase", "refseq_ac": [ { "id": "XP_643824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643824", "type": "external" } ], "gene_names_uniprotkb": "gca; DDB_G0275009", "gene_names_refseq": "gcA", "protein_names_uniprotkb": "Guanylyl cyclase, membrane; 4.6.1.2; DdGCA; GCA; Guanylate cyclase", "protein_names_refseq": "guanylyl cyclase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275009); (R-DDI-2514859)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11237875;11522784;11777934;12097910;15875012;2564393", "class_list": "", "function": "Synthesizes cyclic GMP (cGMP) from GTP, after activation by heterotrimeric or monomeric G proteins (PubMed:11237875, PubMed:11522784, PubMed:11777934). Involved in chemotaxis (PubMed:11777934)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q869Y1;Q9XZS0", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" }, { "id": "4.6.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.2", "type": "external" } ], "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001653 peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031252 cell leading edge", "go_biological_process": "GO:0006182 cGMP biosynthetic process;GO:0006935 chemotaxis;GO:0035556 intracellular signal transduction;GO:0007168 receptor guanylyl cyclase signaling pathway;GO:0051602 response to electrical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q553Y7-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q555I8-1", "uniprot_id": [ { "id": "KIF9_DICDI", "url": "https://www.uniprot.org/uniprot/Q555I8", "type": "external" } ], "mass": 136066.0, "length": 1222, "protein_name": "Kinesin-related protein 9", "gene_name": "kif9", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 9", "refseq_ac": [ { "id": "XP_644079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644079", "type": "external" } ], "gene_names_uniprotkb": "kif9; DDB_G0274603; kin2", "gene_names_refseq": "kif9", "protein_names_uniprotkb": "Kinesin-related protein 9; Kinesin family member 9", "protein_names_refseq": "kinesin family member 9", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274603)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;14641909;15875012", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q86HL6;Q86SA4", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016020 membrane;GO:0005871 kinesin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007018 microtubule-based movement;GO:0051661 maintenance of centrosome location;GO:0007098 centrosome cycle;GO:0030705 cytoskeleton-dependent intracellular transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q555I8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q555L5-1", "uniprot_id": [ { "id": "PRDX4_DICDI", "url": "https://www.uniprot.org/uniprot/Q555L5", "type": "external" } ], "mass": 29040.0, "length": 259, "protein_name": "Peroxiredoxin-4", "gene_name": "prdx4", "organism": "Cellular slime mold", "refseq_name": "thioredoxin peroxidase", "refseq_ac": [ { "id": "XP_644051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644051", "type": "external" } ], "gene_names_uniprotkb": "prdx4; DDB_G0274859", "gene_names_refseq": "prdx4", "protein_names_uniprotkb": "Peroxiredoxin-4; 1.11.1.24; Thioredoxin-dependent peroxiredoxin 4", "protein_names_refseq": "thioredoxin peroxidase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274859); (R-DDI-5628897); (R-DDI-6798695); (R-DDI-9818027)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "12097910;15470253;15875012;16926386;18990192;19482547", "class_list": "", "function": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q555L4;Q8MP16", "ec_number_list": [ { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0008379 thioredoxin peroxidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0045454 cell redox homeostasis;GO:0042744 hydrogen peroxide catabolic process;GO:0046689 response to mercury ion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q555L5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q555X4-1", "uniprot_id": [ { "id": "GNT15_DICDI", "url": "https://www.uniprot.org/uniprot/Q555X4", "type": "external" } ], "mass": 59898.0, "length": 516, "protein_name": "Glycosyltransferase-like protein gnt15", "gene_name": "gnt15", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643936", "type": "external" } ], "gene_names_uniprotkb": "gnt15; DDB_G0274741", "gene_names_refseq": "gnt15", "protein_names_uniprotkb": "Glycosyltransferase-like protein gnt15", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274741)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;17588537", "class_list": "", "function": "May have a role in modulating cell adhesion and glycosylation. Essential for development., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042285 xylosyltransferase activity;GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0035269 protein O-linked glycosylation via mannose;GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q555X4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556G3-1", "uniprot_id": [ { "id": "GSTA2_DICDI", "url": "https://www.uniprot.org/uniprot/Q556G3", "type": "external" } ], "mass": 22538.0, "length": 198, "protein_name": "Putative glutathione S-transferase alpha-2", "gene_name": "gsta2-1; gsta2-2", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644399", "type": "external" } ], "gene_names_uniprotkb": "gsta2-1; gsta2-2; DDB_G0272632; DDB_G0274081", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative glutathione S-transferase alpha-2; 2.5.1.18; GST class-alpha 2", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272632); (ddi:DDB_G0274081); (R-DDI-156590); (R-DDI-2162123)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12097910;15875012;16926386", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86AN9", "ec_number_list": [ { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "5.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.2", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0045335 phagocytic vesicle", "go_biological_process": "GO:1904643 response to curcumin;GO:0006749 glutathione metabolic process;GO:0031153 slug development involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q556G3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556J0-1", "uniprot_id": [ { "id": "TKT_DICDI", "url": "https://www.uniprot.org/uniprot/Q556J0", "type": "external" } ], "mass": 71957.0, "length": 661, "protein_name": "Transketolase", "gene_name": "tkt-1; tkt-2", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644368", "type": "external" } ], "gene_names_uniprotkb": "tkt-1; tkt-2; DDB_G0272618; DDB_G0274019", "gene_names_refseq": "tkt-2", "protein_names_uniprotkb": "Transketolase; 2.2.1.1; TK", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272618); (ddi:DDB_G0274019)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;16926386", "class_list": "", "function": "Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity). Thus, catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86K10", "ec_number_list": [ { "id": "2.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.2.1.1", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004802 transketolase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q556J0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556N5-1", "uniprot_id": [ { "id": "ADRM1_DICDI", "url": "https://www.uniprot.org/uniprot/Q556N5", "type": "external" } ], "mass": 32349.0, "length": 287, "protein_name": "Proteasomal ubiquitin receptor ADRM1 homolog", "gene_name": "adrm1-1; adrm1-2", "organism": "Cellular slime mold", "refseq_name": "adhesion regulating molecule family protein", "refseq_ac": [ { "id": "XP_644405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644405", "type": "external" } ], "gene_names_uniprotkb": "adrm1-1; adrm1-2; DDB_G0272624; DDB_G0274093", "gene_names_refseq": "adrm1-2", "protein_names_uniprotkb": "Proteasomal ubiquitin receptor ADRM1 homolog", "protein_names_refseq": "adhesion regulating molecule family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272624); (ddi:DDB_G0274093); (R-DDI-1236978); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-187577); (R-DDI-2467813); (R-DDI-349425); (R-DDI-382556); (R-DDI-450408); (R-DDI-4641258); (R-DDI-5632684); (R-DDI-5658442); (R-DDI-5687128); (R-DDI-5689603); (R-DDI-5689880); (R-DDI-68949); (R-DDI-69017); (R-DDI-69601); (R-DDI-75815); (R-DDI-8854050); (R-DDI-8948751); (R-DDI-8951664); (R-DDI-9755511); (R-DDI-983168); (R-DDI-9907900); (R-DDI-9929491); (R-DDI-9954709)", "pathway_count": 29, "publication_count": 3, "publication_id_list": "12097910;15875012;16987957", "class_list": "", "function": "Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation (PubMed:16987957)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MYI8", "ec_number_list": [], "go_molecular_function": "GO:0061133 endopeptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000502 proteasome complex;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0031670 cellular response to nutrient;GO:0030154 cell differentiation;GO:0006368 transcription elongation by RNA polymerase II;GO:0043248 proteasome assembly;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q556N5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556Q3-1", "uniprot_id": [ { "id": "IRLF_DICDI", "url": "https://www.uniprot.org/uniprot/Q556Q3", "type": "external" } ], "mass": 164197.0, "length": 1400, "protein_name": "Probable serine/threonine-protein kinase irlF", "gene_name": "irlF-1; irlF-2", "organism": "Cellular slime mold", "refseq_name": "IRE family protein kinase", "refseq_ac": [ { "id": "XP_644568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644568", "type": "external" } ], "gene_names_uniprotkb": "irlF-1; irlF-2; DDB_G0273171; DDB_G0273903", "gene_names_refseq": "irlF-2", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase irlF; 2.7.11.1; Inositol-requiring protein-like protein kinase F", "protein_names_refseq": "IRE family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273171); (ddi:DDB_G0273903); (R-DDI-381070)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86AL1", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0004521 RNA endonuclease activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006397 mRNA processing;GO:0036498 IRE1-mediated unfolded protein response;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q556Q3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556R7-1", "uniprot_id": [ { "id": "CF50_DICDI", "url": "https://www.uniprot.org/uniprot/Q556R7", "type": "external" } ], "mass": 30854.0, "length": 303, "protein_name": "Counting factor 50", "gene_name": "cf50-1; cf50-2", "organism": "Cellular slime mold", "refseq_name": "component of the counting factor complex", "refseq_ac": [ { "id": "XP_644554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644554", "type": "external" } ], "gene_names_uniprotkb": "cf50-1; cf50-2; DDB_G0273175; DDB_G0273875", "gene_names_refseq": "cf50-2", "protein_names_uniprotkb": "Counting factor 50; 1,4-beta-N-acetylmuramidase 1; 3.2.1.17; GH family 25 lysozyme 1", "protein_names_refseq": "component of the counting factor complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273175); (ddi:DDB_G0273875)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10444594;12097910;12117815;12912898;15875012;16963635", "class_list": "glycogene;glycosylhydrolase", "function": "Cell-counting factor that limits the maximum size of the multicellular structure during aggregation. Has a very low lysozyme activity., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q86JX6;Q95VT3", "ec_number_list": [], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007165 signal transduction;GO:0030154 cell differentiation;GO:0098609 cell-cell adhesion;GO:0042593 glucose homeostasis;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q556R7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556S2-1", "uniprot_id": [ { "id": "PAKH_DICDI", "url": "https://www.uniprot.org/uniprot/Q556S2", "type": "external" } ], "mass": 57705.0, "length": 513, "protein_name": "Serine/threonine-protein kinase pakH", "gene_name": "pakH-1; pakH-2", "organism": "Cellular slime mold", "refseq_name": "PAKL subfamily protein kinase", "refseq_ac": [ { "id": "XP_644549", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644549", "type": "external" } ], "gene_names_uniprotkb": "pakH-1; pakH-2; DDB_G0273121; DDB_G0273865", "gene_names_refseq": "pakH-2", "protein_names_uniprotkb": "Serine/threonine-protein kinase pakH; 2.7.11.1", "protein_names_refseq": "PAKL subfamily protein kinase; STE20 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273121); (ddi:DDB_G0273865); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86JX3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0035556 intracellular signal transduction;GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q556S2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556Y4-1", "uniprot_id": [ { "id": "KC1_DICDI", "url": "https://www.uniprot.org/uniprot/Q556Y4", "type": "external" } ], "mass": 49215.0, "length": 426, "protein_name": "Casein kinase I", "gene_name": "cak1-1; cak1-2", "organism": "Cellular slime mold", "refseq_name": "casein kinase I", "refseq_ac": [ { "id": "XP_644485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644485", "type": "external" } ], "gene_names_uniprotkb": "cak1-1; cak1-2; DDB_G0273059; DDB_G0273737", "gene_names_refseq": "cak1-2", "protein_names_uniprotkb": "Casein kinase I; 2.7.11.1; CK1; DdCK1", "protein_names_refseq": "casein kinase I; protein kinase, CK1 group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273059); (ddi:DDB_G0273737); (R-DDI-6791226); (R-DDI-69601)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10880352;12097910;15548420;15875012", "class_list": "", "function": "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. May have a role in DNA repair mechanism and support vegetative growth of the cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O96300;Q86AI9", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.1.26.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.5", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006897 endocytosis;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q556Y4-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q556Y8-1", "uniprot_id": [ { "id": "DUSPR_DICDI", "url": "https://www.uniprot.org/uniprot/Q556Y8", "type": "external" } ], "mass": 53798.0, "length": 476, "protein_name": "Probable rhodanese domain-containing dual specificity protein phosphatase", "gene_name": "DDB_G0273199; DDB_G0273729", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644481", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0273199; DDB_G0273729", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable rhodanese domain-containing dual specificity protein phosphatase; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273199); (ddi:DDB_G0273729); (R-DDI-112409); (R-DDI-202670); (R-DDI-5675221)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Has a dual specificity toward Ser/Thr and Tyr-containing proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86JT3", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0072718 response to cisplatin;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q556Y8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q557E4-1", "uniprot_id": [ { "id": "SKP1B_DICDI", "url": "https://www.uniprot.org/uniprot/Q557E4", "type": "external" } ], "mass": 18702.0, "length": 162, "protein_name": "SCF ubiquitin ligase complex protein SKP1b", "gene_name": "fpaB-1; fpaB-2", "organism": "Cellular slime mold", "refseq_name": "cytosolic glycoprotein FP21", "refseq_ac": [ { "id": "XP_644424", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644424", "type": "external" } ], "gene_names_uniprotkb": "fpaB-1; fpaB-2; DDB_G0273251; DDB_G0273615; fp21B; fpa1B; fpa2; skp1B", "gene_names_refseq": "fpaB-2", "protein_names_uniprotkb": "SCF ubiquitin ligase complex protein SKP1b; Glycoprotein FP21 isoform B", "protein_names_refseq": "cytosolic glycoprotein FP21; ubiquitin ligase subunit SKP1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273251); (ddi:DDB_G0273615); (R-DDI-187577); (R-DDI-68949); (R-DDI-69231); (R-DDI-69601); (R-DDI-8854050); (R-DDI-8951664); (R-DDI-917937); (R-DDI-983168)", "pathway_count": 10, "publication_count": 9, "publication_id_list": "11358877;11886837;12097910;12244067;15123660;1577798;15875012;9373134;9660787", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0097602 cullin family protein binding;GO:1990444 F-box domain binding;GO:0071987 WD40-repeat domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0043223 cytoplasmic SCF ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q557E4-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q557E6-1", "uniprot_id": [ { "id": "Q557E6_DICDI", "url": "https://www.uniprot.org/uniprot/Q557E6", "type": "external" } ], "mass": 38881.0, "length": 351, "protein_name": "DNA repair protein RAD51 homolog", "gene_name": "DDB_G0273139; DDB_G0273611", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644422", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0273139; DDB_G0273611", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA repair protein RAD51 homolog", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273139); (ddi:DDB_G0273611); (R-DDI-5685938); (R-DDI-5693616)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86HZ4", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0008094 ATP-dependent activity, acting on DNA;GO:0000150 DNA strand exchange activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006312 mitotic recombination;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0007155 cell adhesion;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q557E6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q557E7-1", "uniprot_id": [ { "id": "CBLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q557E7", "type": "external" } ], "mass": 74962.0, "length": 665, "protein_name": "E3 ubiquitin-protein ligase cblA", "gene_name": "cblA-1; cblA-2", "organism": "Cellular slime mold", "refseq_name": "EF-hand-like domain-containing protein", "refseq_ac": [ { "id": "XP_644421", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644421", "type": "external" } ], "gene_names_uniprotkb": "cblA-1; cblA-2; DDB_G0273141; DDB_G0273609", "gene_names_refseq": "cblA-2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase cblA; 2.3.2.27; Cbl-like protein A; RING finger protein cblA; RING-type E3 ubiquitin transferase cblA", "protein_names_refseq": "EF-hand-like domain-containing protein; RING zinc finger-containing protein; SH2 domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273141); (ddi:DDB_G0273609); (R-DDI-983168)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12097910;15875012;18840649", "class_list": "", "function": "Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Up-regulates STATc tyrosine phosphorylation via an inhibitory effect on ptpC accumulation. Recognizes activated receptor tyrosine kinases, RTKs and terminates signaling., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86HZ3", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016567 protein ubiquitination;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q557E7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q557G1-1", "uniprot_id": [ { "id": "IRLB_DICDI", "url": "https://www.uniprot.org/uniprot/Q557G1", "type": "external" } ], "mass": 169401.0, "length": 1448, "protein_name": "Probable serine/threonine-protein kinase irlB", "gene_name": "irlB-1; irlB-2", "organism": "Cellular slime mold", "refseq_name": "IRE family protein kinase", "refseq_ac": [ { "id": "XP_644545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644545", "type": "external" } ], "gene_names_uniprotkb": "irlB-1; irlB-2; DDB_G0273333; DDB_G0273857", "gene_names_refseq": "irlB-2", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase irlB; 2.7.11.1; Inositol-requiring protein-like protein kinase B", "protein_names_refseq": "IRE family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273333); (ddi:DDB_G0273857); (R-DDI-381070)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0004521 RNA endonuclease activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006397 mRNA processing;GO:0036498 IRE1-mediated unfolded protein response;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q557G1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q557I6-1", "uniprot_id": [ { "id": "Q557I6_DICDI", "url": "https://www.uniprot.org/uniprot/Q557I6", "type": "external" } ], "mass": 63029.0, "length": 552, "protein_name": "MEK1 interacting protein 1", "gene_name": "mip1-2", "organism": "Cellular slime mold", "refseq_name": "MEK1 interacting protein 1", "refseq_ac": [ { "id": "XP_644602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644602", "type": "external" } ], "gene_names_uniprotkb": "mip1-2; DDB_G0273399; DDB_G0273535; mip1-1", "gene_names_refseq": "mip1-1", "protein_names_uniprotkb": "MEK1 interacting protein 1", "protein_names_refseq": "MEK1 interacting protein 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273399); (ddi:DDB_G0273535); (R-DDI-983168)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SSQ6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031434 mitogen-activated protein kinase kinase binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0030010 establishment of cell polarity;GO:0051457 maintenance of protein location in nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q557I6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q557J6-1", "uniprot_id": [ { "id": "DBNL_DICDI", "url": "https://www.uniprot.org/uniprot/Q557J6", "type": "external" } ], "mass": 55338.0, "length": 481, "protein_name": "Drebrin-like protein", "gene_name": "abpE-1; abpE-2", "organism": "Cellular slime mold", "refseq_name": "actin binding protein E", "refseq_ac": [ { "id": "XP_644611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644611", "type": "external" } ], "gene_names_uniprotkb": "abpE-1; abpE-2; DDB_G0273447; DDB_G0273517; abp1-1; abp1-2", "gene_names_refseq": "abpE-1", "protein_names_uniprotkb": "Drebrin-like protein; Actin-binding protein 1; Actin-binding protein E; Dabp1", "protein_names_refseq": "actin binding protein E", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273447); (ddi:DDB_G0273517); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12097910;15875012;16449327", "class_list": "", "function": "Actin-binding adapter protein. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin. Controls pseudopodium number and motility in early stages of chemotactic aggregation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6T3S4", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0019901 protein kinase binding;GO:0051015 actin filament binding;GO:0005522 profilin binding;GO:0032037 myosin I heavy chain binding", "go_cellular_component": "GO:0031252 cell leading edge;GO:0045335 phagocytic vesicle;GO:0031143 pseudopodium;GO:0030864 cortical actin cytoskeleton;GO:0030427 site of polarized growth", "go_biological_process": "GO:0090382 phagosome maturation;GO:0051017 actin filament bundle assembly;GO:0050765 negative regulation of phagocytosis;GO:0048870 cell motility;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q557J6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q558K8-1", "uniprot_id": [ { "id": "ICMT_DICDI", "url": "https://www.uniprot.org/uniprot/Q558K8", "type": "external" } ], "mass": 27379.0, "length": 237, "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase", "gene_name": "icmt-1; icmt-2", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "icmt-1; icmt-2; DDB_G0272799; DDB_G0273995; icmA", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein-S-isoprenylcysteine O-methyltransferase; 2.1.1.100; Isoprenylcysteine carboxylmethyltransferase; PPMT; Prenylated protein carboxyl methyltransferase; Prenylcysteine carboxyl methyltransferase; pcCMT", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272799); (ddi:DDB_G0273995); (R-DDI-163841); (R-DDI-9648002)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12097910;15875012;17699599", "class_list": "", "function": "Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86AM7;Q8T623", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.1.1.100", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.100", "type": "external" } ], "go_molecular_function": "GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0034504 protein localization to nucleus;GO:0006998 nuclear envelope organization;GO:0030010 establishment of cell polarity;GO:0032259 methylation;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q558K8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q558U1-1", "uniprot_id": [ { "id": "IFKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q558U1", "type": "external" } ], "mass": 252390.0, "length": 2258, "protein_name": "Probable serine/threonine-protein kinase ifkA", "gene_name": "ifkA", "organism": "Cellular slime mold", "refseq_name": "GCN2 subfamily protein kinase", "refseq_ac": [ { "id": "XP_644975", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644975", "type": "external" } ], "gene_names_uniprotkb": "ifkA; DDB_G0272837", "gene_names_refseq": "ifkA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase ifkA; 2.7.11.1; Initiation factor kinase A", "protein_names_refseq": "GCN2 subfamily protein kinase; PEK family protein kinase; anticodon-binding domain-containing protein; eukaryotic translation initiation factor 2 alpha kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272837)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;12697064;15875012;17177855", "class_list": "", "function": "Phosphorylates eIF2-alpha, from 1 to 7 hours after the onset of development or during the preaggregation state, resulting in a shift from polysomes to free ribosomes for bulk mRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86B04", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006417 regulation of translation;GO:0048255 mRNA stabilization;GO:0098609 cell-cell adhesion;GO:0006446 regulation of translational initiation;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q558U1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q558Z2-1", "uniprot_id": [ { "id": "SUN1_DICDI", "url": "https://www.uniprot.org/uniprot/Q558Z2", "type": "external" } ], "mass": 104743.0, "length": 905, "protein_name": "Sun domain-containing protein 1", "gene_name": "sun1", "organism": "Cellular slime mold", "refseq_name": "SUN domain-containing protein 1", "refseq_ac": [ { "id": "XP_644924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644924", "type": "external" } ], "gene_names_uniprotkb": "sun1; DDB_G0272869", "gene_names_refseq": "sun1", "protein_names_uniprotkb": "Sun domain-containing protein 1", "protein_names_refseq": "SUN domain-containing protein 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272869)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;15875012;18266910;19632001", "class_list": "", "function": "May have an important role in defining the spacing of the nuclear envelope lumen. Essential for centrosome attachment to the nucleus, maintenance of correct ploidy, proper mitosis, association of the centromere cluster with the centrosome and the maintenance of genome stability. Requires direct chromatin binding for inner nuclear membrane targeting., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005637 nuclear inner membrane;GO:0005640 nuclear outer membrane", "go_biological_process": "GO:0051301 cell division;GO:0007098 centrosome cycle;GO:0051642 centrosome localization;GO:0000070 mitotic sister chromatid segregation;GO:0006997 nucleus organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q558Z2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AI5-1", "uniprot_id": [ { "id": "SUCB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AI5", "type": "external" } ], "mass": 48350.0, "length": 445, "protein_name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "gene_name": "scsC", "organism": "Cellular slime mold", "refseq_name": "ATP-specific succinyl-CoA synthetase beta subunit", "refseq_ac": [ { "id": "XP_645537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645537", "type": "external" } ], "gene_names_uniprotkb": "scsC; DDB_G0271842; sucla2", "gene_names_refseq": "scsC", "protein_names_uniprotkb": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; 6.2.1.5; A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; SCS-betaA; Succinyl-CoA synthetase beta-A chain", "protein_names_refseq": "ATP-specific succinyl-CoA synthetase beta subunit; succinate-CoA ligase; succinyl-CoA synthetase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271842); (R-DDI-71403)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86AG1", "ec_number_list": [ { "id": "6.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.4", "type": "external" }, { "id": "6.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.5", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042709 succinate-CoA ligase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55AI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AN8-1", "uniprot_id": [ { "id": "Y1806_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AN8", "type": "external" } ], "mass": 130198.0, "length": 1167, "protein_name": "PH and Rap-GAP domain-containing protein DDB_G0271806", "gene_name": "DDB_G0271806", "organism": "Cellular slime mold", "refseq_name": "RapGAP/RanGAP domain-containing protein", "refseq_ac": [ { "id": "XP_645484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645484", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0271806", "gene_names_refseq": "", "protein_names_uniprotkb": "PH and Rap-GAP domain-containing protein DDB_G0271806", "protein_names_refseq": "RapGAP/RanGAP domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271806)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", 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0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q86HH0", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0031252 cell leading edge;GO:0031143 pseudopodium;GO:0044354 macropinosome", "go_biological_process": "GO:0032487 regulation of Rap protein signal transduction;GO:0032486 Rap protein signal transduction;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0098609 cell-cell adhesion;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55AN8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AP1-1", "uniprot_id": [ { "id": "GRLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AP1", "type": "external" } ], "mass": 89613.0, "length": 798, "protein_name": "Metabotropic glutamate receptor-like protein A", "gene_name": "grlA", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family 3 protein 1", "refseq_ac": [ { "id": "XP_645481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645481", "type": "external" } ], "gene_names_uniprotkb": "grlA; DDB_G0271684", "gene_names_refseq": "grlA", "protein_names_uniprotkb": "Metabotropic glutamate receptor-like protein A", "protein_names_refseq": "G-protein-coupled receptor family 3 protein 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271684)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12097910;15875012;16735079;17501984;17950724", "class_list": "", "function": "May play an important role in the terminal differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, 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"binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0048471 perinuclear region of cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q55AP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AR3-1", "uniprot_id": [ { "id": "TBG_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AR3", "type": "external" } ], "mass": 52235.0, "length": 462, "protein_name": "Tubulin gamma chain", "gene_name": "tubC", "organism": "Cellular slime mold", "refseq_name": "gamma tubulin", "refseq_ac": [ { "id": "XP_645459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645459", "type": "external" } ], "gene_names_uniprotkb": "tubC; DDB_G0271738", "gene_names_refseq": "tubC", "protein_names_uniprotkb": "Tubulin gamma chain; Gamma-tubulin", "protein_names_refseq": "gamma tubulin; tubulin gamma-2 chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271738)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;15875012;16512674;9275182", "class_list": "", "function": "Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15812;Q75JB6", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding;GO:0140490 microtubule nucleator activity", "go_cellular_component": "GO:0031592 centrosomal corona;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007020 microtubule nucleation;GO:0007052 mitotic spindle organization;GO:0000070 mitotic sister chromatid segregation;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q55AR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AR6-1", "uniprot_id": [ { "id": "NFAA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AR6", "type": "external" } ], "mass": 103972.0, "length": 920, "protein_name": "Neurofibromin-A", "gene_name": "nfaA", "organism": "Cellular slime mold", "refseq_name": "Ras GTPase activation domain-containing protein", "refseq_ac": [ { "id": "XP_645456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645456", "type": "external" } ], "gene_names_uniprotkb": "nfaA; DDB_G0271750", "gene_names_refseq": "nfaA", "protein_names_uniprotkb": "Neurofibromin-A; DdNF1", "protein_names_refseq": "Ras GTPase activation domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271750); (R-DDI-5218921); (R-DDI-5658442); (R-DDI-8849471)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12097910;15875012;18948008", "class_list": "", "function": "Regulator of the GTPase activity of Ras, mainly RasG and RasB., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:1902531 regulation of intracellular signal transduction;GO:0050920 regulation of chemotaxis;GO:0033058 directional locomotion;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55AR6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AX0-1", "uniprot_id": [ { "id": "DLPC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AX0", "type": "external" } ], "mass": 104370.0, "length": 904, "protein_name": "Dynamin-like protein C", "gene_name": "dlpC", "organism": "Cellular slime mold", "refseq_name": "dynamin like protein", "refseq_ac": [ { "id": "XP_645576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645576", "type": "external" } ], "gene_names_uniprotkb": "dlpC; DDB_G0271628", "gene_names_refseq": "dlpC", "protein_names_uniprotkb": "Dynamin-like protein C; 3.6.5.5", "protein_names_refseq": "dynamin like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271628)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;18809930", "class_list": "", "function": "Involved in cytokinesis. May hydrolyze GTP., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86JH7", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016020 membrane", "go_biological_process": "GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55AX0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55AX2-1", "uniprot_id": [ { "id": "DOT1L_DICDI", "url": "https://www.uniprot.org/uniprot/Q55AX2", "type": "external" } ], "mass": 212281.0, "length": 1845, "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "dotA", "organism": "Cellular slime mold", "refseq_name": "DOT1 domain-containing protein", "refseq_ac": [ { "id": "XP_645574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645574", "type": "external" } ], "gene_names_uniprotkb": "dotA; DDB_G0271626; KMT4; dot1", "gene_names_refseq": "dotA", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase, H3 lysine-79 specific; 2.1.1.360; Disruptor of telomeric silencing A; H3-K79-HMTase; Histone H3-K79 methyltransferase; SAM domain-containing protein", "protein_names_refseq": "DOT1 domain-containing protein; SAM domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271626)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;21187070", "class_list": "", "function": "Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing, correct growth and development, and for resistance to DNA damage induced by UV LIGHT., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.360", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.360", "type": "external" } ], "go_molecular_function": "GO:0031151 histone H3K79 methyltransferase activity;GO:0140956 histone H3K79 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0032259 methylation;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55AX2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BH9-1", "uniprot_id": [ { "id": "DGAT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BH9", "type": "external" } ], "mass": 71946.0, "length": 617, "protein_name": "Diacylglycerol O-acyltransferase 1", "gene_name": "dgat1", "organism": "Cellular slime mold", "refseq_name": "diacylglycerol O-acyltransferase 1", "refseq_ac": [ { "id": "XP_645633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645633", "type": "external" } ], "gene_names_uniprotkb": "dgat1; DDB_G0271342", "gene_names_refseq": "dgat1", "protein_names_uniprotkb": "Diacylglycerol O-acyltransferase 1; 2.3.1.20; 2.3.1.76; ARAT; Acyl-CoA retinol O-fatty-acyltransferase; Retinol O-fatty-acyltransferase", "protein_names_refseq": "diacylglycerol O-acyltransferase 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271342); (R-DDI-1482883); (R-DDI-6798695); (R-DDI-75109)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0004144 diacylglycerol O-acyltransferase activity;GO:0050252 retinol O-fatty-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008611 ether lipid biosynthetic process;GO:0019432 triglyceride biosynthetic process;GO:0006071 glycerol metabolic process;GO:0140042 lipid droplet formation;GO:0006640 monoacylglycerol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55BH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BN8-1", "uniprot_id": [ { "id": "NEK2_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BN8", "type": "external" } ], "mass": 48933.0, "length": 418, "protein_name": "Probable serine/threonine-protein kinase nek2", "gene_name": "nek2", "organism": "Cellular slime mold", "refseq_name": "NEK family protein kinase", "refseq_ac": [ { "id": "XP_646793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646793", "type": "external" } ], "gene_names_uniprotkb": "nek2; DDB_G0270814", "gene_names_refseq": "nek2", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase nek2; 2.7.11.1; Never in mitosis protein A-related protein kinase 2; NimA-related protein kinase 2", "protein_names_refseq": "NEK family protein kinase; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270814); (R-DDI-179409)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15548420;15875012;16890490;16926386", "class_list": "", "function": "Involved in centrosome biogenesis. Seems to be required for recruitment of centrosomal material and might be involved in de novo centrosome formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0000086 G2/M transition of mitotic cell cycle;GO:0007098 centrosome cycle;GO:0031023 microtubule organizing center organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q55BN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BN9-1", "uniprot_id": [ { "id": "H33B_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BN9", "type": "external" } ], "mass": 15560.0, "length": 136, "protein_name": "Histone H3.3 type b", "gene_name": "H3b", "organism": "Cellular slime mold", "refseq_name": "histone H3", "refseq_ac": [ { "id": "XP_646792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646792", "type": "external" } ], "gene_names_uniprotkb": "H3b; DDB_G0270838", "gene_names_refseq": "H3b", "protein_names_uniprotkb": "Histone H3.3 type b; Histone 3, variant 3 type b", "protein_names_refseq": "histone H3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270838)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15875012;16469305;16524908;17878305;21187070;497154", "class_list": "", "function": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0000786 nucleosome;GO:0030874 nucleolar chromatin", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0006338 chromatin remodeling;GO:0007346 regulation of mitotic cell cycle;GO:0007080 mitotic metaphase chromosome alignment;GO:0046689 response to mercury ion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q55BN9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BP0-1", "uniprot_id": [ { "id": "H33C_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BP0", "type": "external" } ], "mass": 15601.0, "length": 136, "protein_name": "Histone H3.3 type c", "gene_name": "H3c", "organism": "Cellular slime mold", "refseq_name": "histone H3", "refseq_ac": [ { "id": "XP_646791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646791", "type": "external" } ], "gene_names_uniprotkb": "H3c; DDB_G0271092", "gene_names_refseq": "H3c", "protein_names_uniprotkb": "Histone H3.3 type c; Histone 3, variant 3 type c", "protein_names_refseq": "histone H3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271092)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15875012;16469305;16524908;21187070;497154", "class_list": "", "function": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0000786 nucleosome", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0007080 mitotic metaphase chromosome alignment;GO:0034644 cellular response to UV;GO:0040029 epigenetic regulation of gene expression;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q55BP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BP5-1", "uniprot_id": [ { "id": "TOP2_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BP5", "type": "external" } ], "mass": 171162.0, "length": 1521, "protein_name": "Probable DNA topoisomerase 2", "gene_name": "top2", "organism": "Cellular slime mold", "refseq_name": "DNA topoisomerase II", "refseq_ac": [ { "id": "XP_646786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646786", "type": "external" } ], "gene_names_uniprotkb": "top2; DDB_G0270418; topB", "gene_names_refseq": "top2", "protein_names_uniprotkb": "Probable DNA topoisomerase 2; 5.6.2.2; DNA topoisomerase II", "protein_names_refseq": "DNA topoisomerase II", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270418); (R-DDI-4615885)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.2", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0006265 DNA topological change;GO:0000819 sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55BP5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BW0-1", "uniprot_id": [ { "id": "RAPC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BW0", "type": "external" } ], "mass": 30710.0, "length": 278, "protein_name": "Ras-related protein rapC", "gene_name": "rapC", "organism": "Cellular slime mold", "refseq_name": "Ras GTPase", "refseq_ac": [ { "id": "XP_646721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646721", "type": "external" } ], "gene_names_uniprotkb": "rapC; DDB_G0270340", "gene_names_refseq": "rapC", "protein_names_uniprotkb": "Ras-related protein rapC; 3.6.5.2", "protein_names_refseq": "Ras GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270340); (R-DDI-354192); (R-DDI-392517); (R-DDI-6798695)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.4.23.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.-", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "3.2.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.25", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0007264 small GTPase-mediated signal transduction;GO:0000281 mitotic cytokinesis;GO:1900025 negative regulation of substrate adhesion-dependent cell spreading;GO:0010812 negative regulation of cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55BW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55BW2-1", "uniprot_id": [ { "id": "HDA12_DICDI", "url": "https://www.uniprot.org/uniprot/Q55BW2", "type": "external" } ], "mass": 48641.0, "length": 422, "protein_name": "Histone deacetylase B", "gene_name": "hdaB", "organism": "Cellular slime mold", "refseq_name": "histone deacetylase family protein", "refseq_ac": [ { "id": "XP_646719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646719", "type": "external" } ], "gene_names_uniprotkb": "hdaB; DDB_G0270338", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone deacetylase B; 3.5.1.98; DdHdaB; Type-1 histone deacetylase 2", "protein_names_refseq": "histone deacetylase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270338); (R-DDI-9701898)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;19576222", "class_list": "", "function": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May play a role in the regulation of the timing of gene expression during the development and in the definition aspects of the phenotype that mediate social behavior in genetically heterogeneous groups., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004407 histone deacetylase activity;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0040029 epigenetic regulation of gene expression;GO:0043934 sporulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55BW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55C16-1", "uniprot_id": [ { "id": "UBA1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55C16", "type": "external" } ], "mass": 113745.0, "length": 1017, "protein_name": "Ubiquitin-like modifier-activating enzyme 1", "gene_name": "uba1", "organism": "Cellular slime mold", "refseq_name": "ubiquitin activating enzyme E1", "refseq_ac": [ { "id": "XP_646665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646665", "type": "external" } ], "gene_names_uniprotkb": "uba1; DDB_G0270272; uae1", "gene_names_refseq": "uae1", "protein_names_uniprotkb": "Ubiquitin-like modifier-activating enzyme 1; 6.2.1.45; Ubiquitin-activating enzyme E1", "protein_names_refseq": "ubiquitin activating enzyme E1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270272); (R-DDI-1169408); (R-DDI-8866652); (R-DDI-936440); (R-DDI-983168); (R-DDI-9909505)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. 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for transferring electrons from succinate to ubiquinone (coenzyme Q)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.5.1", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0022904 respiratory electron transport chain;GO:0009060 aerobic respiration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55CC2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CC5-1", "uniprot_id": [ { "id": "BECNA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CC5", "type": "external" } ], "mass": 155666.0, "length": 1368, "protein_name": "Beclin-1-like protein A", "gene_name": "atg6A", "organism": "Cellular slime mold", "refseq_name": "autophagy protein 6", "refseq_ac": [ { "id": "XP_646556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646556", "type": "external" } ], "gene_names_uniprotkb": "atg6A; DDB_G0269244; apg6A; apg6; atg6", "gene_names_refseq": "atg6A", "protein_names_uniprotkb": "Beclin-1-like protein A; Autophagy-related protein 6A", "protein_names_refseq": "autophagy protein 6; autophagy protein Apg6 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269244)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12626495;14736886;15875012;19667176", "class_list": "", "function": "Involved in autophagy (PubMed:12626495, PubMed:14736886). May be required to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium (PubMed:19667176)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q86CS0", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0010008 endosome membrane;GO:0000407 phagophore assembly site;GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0001878 response to yeast;GO:0015031 protein transport;GO:0016236 macroautophagy;GO:0000423 mitophagy", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q55CC5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CH0-1", "uniprot_id": [ { "id": "ADCC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CH0", "type": "external" } ], "mass": 74207.0, "length": 654, "protein_name": "Arrestin domain-containing protein C", "gene_name": "adcC", "organism": "Cellular slime mold", "refseq_name": "C2 calcium-dependent membrane targeting domain-containing protein", "refseq_ac": [ { "id": "XP_646511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646511", "type": "external" } ], "gene_names_uniprotkb": "adcC; DDB_G0271022", "gene_names_refseq": "adcC", "protein_names_uniprotkb": "Arrestin domain-containing protein C", "protein_names_refseq": "C2 calcium-dependent membrane targeting domain-containing protein; SAM domain-containing protein; arrestin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271022)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17659086", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042802 identical protein binding;GO:0008603 cAMP-dependent protein kinase regulator activity;GO:0031210 phosphatidylcholine binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0002031 G protein-coupled receptor internalization;GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55CH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CK2-1", "uniprot_id": [ { "id": "MGP2_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CK2", "type": "external" } ], "mass": 97411.0, "length": 877, "protein_name": "GTPase activating protein homolog 2", "gene_name": "mgp2", "organism": "Cellular slime mold", "refseq_name": "Cdc15/Fes/CIP4 domain-containing protein", "refseq_ac": [ { "id": "XP_646479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646479", "type": "external" } ], "gene_names_uniprotkb": "mgp2; DDB_G0270024; gacCC", "gene_names_refseq": "mgp2", "protein_names_uniprotkb": "GTPase activating protein homolog 2; GTPase activating factor for raC protein CC; Rho GTPase-activating protein gacCC", "protein_names_refseq": "Cdc15/Fes/CIP4 domain-containing protein; PCH family protein; RhoGAP domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270024)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18334553", "class_list": "", "function": "Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000331 contractile vacuole", "go_biological_process": "GO:0007165 signal transduction;GO:0006887 exocytosis;GO:0051490 negative regulation of filopodium assembly;GO:0042331 phototaxis;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55CK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CL6-1", "uniprot_id": [ { "id": "MP2K1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CL6", "type": "external" } ], "mass": 74138.0, "length": 660, "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "mekA", "organism": "Cellular slime mold", "refseq_name": "MAP kinase kinase", "refseq_ac": [ { "id": "XP_646465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646465", "type": "external" } ], "gene_names_uniprotkb": "mekA; DDB_G0269152; MEK1", "gene_names_refseq": "mekA", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase 1; 2.7.12.2; DdMEK1; ERK activator kinase 1; MAP kinase kinase 1; MAPK/ERK kinase 1; MAPK/ERK kinase A; MAPKK 1; MEK1; MEKA", "protein_names_refseq": "MAP kinase kinase; STE7 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269152)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12062087;15875012;9250676", "class_list": "", "function": "Required for cAMP-mediated activation of guanylyl cyclase activity and plays an essential role in aggregation, morphogenesis, and chemotaxis. Appears to act upstream of erk1 but not erk2., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O00885", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0016020 membrane;GO:0031252 cell leading edge", "go_biological_process": "GO:0072697 protein localization to cell cortex;GO:0007165 signal transduction;GO:0000165 MAPK cascade;GO:0030587 sorocarp development;GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55CL6-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CP6-1", "uniprot_id": [ { "id": "DDX1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CP6", "type": "external" } ], "mass": 84828.0, "length": 765, "protein_name": "ATP-dependent RNA helicase ddx1", "gene_name": "ddx1", "organism": "Cellular slime mold", "refseq_name": "DEAD/DEAH box helicase", "refseq_ac": [ { "id": "XP_646435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646435", "type": "external" } ], "gene_names_uniprotkb": "ddx1; DDB_G0269966", "gene_names_refseq": "ddx1", "protein_names_uniprotkb": "ATP-dependent RNA helicase ddx1; 3.6.4.13; DEAD box protein 1", "protein_names_refseq": "DEAD/DEAH box helicase; SPla/RYanodine receptor SPRY domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269966)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. It is also an accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0033677 DNA/RNA helicase activity;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004527 exonuclease activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55CP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CS7-1", "uniprot_id": [ { "id": "MPL1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CS7", "type": "external" } ], "mass": 94023.0, "length": 834, "protein_name": "MAP kinase phosphatase with leucine-rich repeats protein 1", "gene_name": "mpl1", "organism": "Cellular slime mold", "refseq_name": "leucine-rich repeat-containing protein", "refseq_ac": [ { "id": "XP_646404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646404", "type": "external" } ], "gene_names_uniprotkb": "mpl1; DDB_G0269918", "gene_names_refseq": "mpl1", "protein_names_uniprotkb": "MAP kinase phosphatase with leucine-rich repeats protein 1; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "leucine-rich repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269918)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;18408056", "class_list": "", "function": "Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins (By similarity). Dephosphorylates pNPP, in vitro. Essential for proper regulation of erkB (erk2) and optimal motility during development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0048870 cell motility;GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0031152 aggregation involved in sorocarp development;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55CS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CS9-1", "uniprot_id": [ { "id": "ATPB_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CS9", "type": "external" } ], "mass": 70845.0, "length": 651, "protein_name": "ATP synthase F(1) complex catalytic subunit beta, mitochondrial", "gene_name": "atp5f1b", "organism": "Cellular slime mold", "refseq_name": "ATP synthase beta chain, mitochondrial", "refseq_ac": [ { "id": "XP_646402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646402", "type": "external" } ], "gene_names_uniprotkb": "atp5f1b; DDB_G0269916; atp5b", "gene_names_refseq": "atp5b", "protein_names_uniprotkb": "ATP synthase F(1) complex catalytic subunit beta, mitochondrial; 7.1.2.2; ATP synthase F1 subunit beta", "protein_names_refseq": "ATP synthase beta chain, mitochondrial", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269916); (R-DDI-1268020); (R-DDI-9837999)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15875012;16512674;16926386", "class_list": "", "function": "Catalytic subunit beta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the subunit alpha (ATP5F1A), forms the catalytic core in the F(1) domain (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "1.3.8.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.-", "type": "external" }, { "id": "2.8.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.3.5", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.3", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.5.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.39", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.3.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.16", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "6.4.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045335 phagocytic vesicle;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0046689 response to mercury ion;GO:0015986 proton motive force-driven ATP synthesis;GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55CS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CT0-1", "uniprot_id": [ { "id": "TPP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CT0", "type": "external" } ], "mass": 67296.0, "length": 600, "protein_name": "Tripeptidyl-peptidase 1", "gene_name": "tpp1", "organism": "Cellular slime mold", "refseq_name": "peptidase S8 and S53 domain-containing protein", "refseq_ac": [ { "id": "XP_646401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646401", "type": "external" } ], "gene_names_uniprotkb": "tpp1; DDB_G0269914", "gene_names_refseq": "tpp1", "protein_names_uniprotkb": "Tripeptidyl-peptidase 1; 3.4.14.9; TPP-1; TPP-I; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase I", "protein_names_refseq": "peptidase S8 and S53 domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269914)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Serine protease with tripeptidyl-peptidase I activity., [UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding;GO:0008240 tripeptidyl-peptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "GO:0006508 proteolysis;GO:0006909 phagocytosis;GO:0044351 macropinocytosis;GO:1902349 response to chloroquine;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55CT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CT1-1", "uniprot_id": [ { "id": "NCPR_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CT1", "type": "external" } ], "mass": 76193.0, "length": 667, "protein_name": "NADPH--cytochrome P450 reductase", "gene_name": "redB", "organism": "Cellular slime mold", "refseq_name": "NADPH-cytochrome-P450 oxidoreductase", "refseq_ac": [ { "id": "XP_646400", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646400", "type": "external" } ], "gene_names_uniprotkb": "redB; DDB_G0269912", "gene_names_refseq": "redB", "protein_names_uniprotkb": "NADPH--cytochrome P450 reductase; 1.6.2.4; CPR; NADPH oxidoreductase B; P450R", "protein_names_refseq": "NADPH-cytochrome-P450 oxidoreductase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269912); (R-DDI-1222556); (R-DDI-1474151); (R-DDI-203615); (R-DDI-203754); (R-DDI-392154); (R-DDI-5218920); (R-DDI-5578775); (R-DDI-9009391); (R-DDI-9033241); (R-DDI-9856530)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "15875012;18218133", "class_list": "", "function": "This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.10", "type": "external" }, { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.-", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" }, { "id": "4.2.1.119", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.119", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "1.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.4", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016491 oxidoreductase activity;GO:0010181 FMN binding;GO:0050661 NADP binding;GO:0003958 NADPH-hemoprotein reductase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55CT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CT4-1", "uniprot_id": [ { "id": "Q55CT4_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CT4", "type": "external" } ], "mass": 98574.0, "length": 861, "protein_name": "Aminopeptidase", "gene_name": "psaA", "organism": "Cellular slime mold", "refseq_name": "puromycin-sensitive aminopeptidase-like protein", "refseq_ac": [ { "id": "XP_646397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646397", "type": "external" } ], "gene_names_uniprotkb": "psaA; DDB_G0270994", "gene_names_refseq": "psaA", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "puromycin-sensitive aminopeptidase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270994); (R-DDI-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0004177 aminopeptidase activity;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0043171 peptide catabolic process;GO:0098609 cell-cell adhesion;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55CT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CY9-1", "uniprot_id": [ { "id": "GDT8_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CY9", "type": "external" } ], "mass": 150109.0, "length": 1326, "protein_name": "Probable serine/threonine-protein kinase gdt8", "gene_name": "gdt8", "organism": "Cellular slime mold", "refseq_name": "GDT family protein kinase", "refseq_ac": [ { "id": "XP_646342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646342", "type": "external" } ], "gene_names_uniprotkb": "gdt8; DDB_G0270668", "gene_names_refseq": "gdt8", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase gdt8; 2.7.11.1; Growth-differentiation transition protein 8", "protein_names_refseq": "GDT family protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270668)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15236669;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050793 regulation of developmental process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55CY9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55CZ1-1", "uniprot_id": [ { "id": "GDT2_DICDI", "url": "https://www.uniprot.org/uniprot/Q55CZ1", "type": "external" } ], "mass": 184901.0, "length": 1637, "protein_name": "Probable serine/threonine-protein kinase gdt2", "gene_name": "gdt2", "organism": "Cellular slime mold", "refseq_name": "GDT family protein kinase", "refseq_ac": [ { "id": "XP_646340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646340", "type": "external" } ], "gene_names_uniprotkb": "gdt2; DDB_G0270666", "gene_names_refseq": "gdt2", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase gdt2; 2.7.11.1; Growth-differentiation transition protein 2", "protein_names_refseq": "GDT family protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270666)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15236669;15875012", "class_list": "", "function": "Regulates the transition between growth and differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0051093 negative regulation of developmental process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55CZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55D99-1", "uniprot_id": [ { "id": "PAKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55D99", "type": "external" } ], "mass": 134650.0, "length": 1197, "protein_name": "Serine/threonine-protein kinase pakA", "gene_name": "pakA", "organism": "Cellular slime mold", "refseq_name": "PAKA subfamily protein kinase", "refseq_ac": [ { "id": "XP_646232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646232", "type": "external" } ], "gene_names_uniprotkb": "pakA; DDB_G0269166", "gene_names_refseq": "pakA", "protein_names_uniprotkb": "Serine/threonine-protein kinase pakA; 2.7.11.1; dPAKa; dpak1", "protein_names_refseq": "PAKA subfamily protein kinase; STE20 family protein kinase; p21-activated protein kinase; protein kinase, STE group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269166); (R-DDI-2029482); (R-DDI-389359); (R-DDI-3928662); (R-DDI-445144); (R-DDI-5621575); (R-DDI-5627123); (R-DDI-5687128); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 11, "publication_count": 3, "publication_id_list": "10545500;11389841;15875012", "class_list": "", "function": "Regulator of the myosin II component of the cytoskeleton: required for regulation of cytokinesis. Functions during chemotaxis, required for maintaining the direction of cell movement, suppressing lateral pseudopod extension, and proper retraction of the posterior of chemotaxing cells., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q23866;Q9XYY3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0045159 myosin II binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005938 cell cortex;GO:0032154 cleavage furrow", "go_biological_process": "GO:0006935 chemotaxis;GO:0035556 intracellular signal transduction;GO:0006909 phagocytosis;GO:0000281 mitotic cytokinesis;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55D99-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DA0-1", "uniprot_id": [ { "id": "ABCGM_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DA0", "type": "external" } ], "mass": 68269.0, "length": 615, "protein_name": "ABC transporter G family member 22", "gene_name": "abcG22", "organism": "Cellular slime mold", "refseq_name": "ABC transporter G family protein", "refseq_ac": [ { "id": "XP_646231", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646231", "type": "external" } ], "gene_names_uniprotkb": "abcG22; DDB_G0270826", "gene_names_refseq": "abcG22", "protein_names_uniprotkb": "ABC transporter G family member 22; ABC transporter ABCG.22", "protein_names_refseq": "ABC transporter G family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270826); (R-DDI-1369062); (R-DDI-1660661); (R-DDI-189451); (R-DDI-189483); (R-DDI-8964058); (R-DDI-917937); (R-DDI-9753281); (R-DDI-9793528)", "pathway_count": 9, "publication_count": 3, "publication_id_list": "15875012;17517120;18164290", "class_list": "", "function": "May be involved in cell migration., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0048870 cell motility;GO:0031152 aggregation involved in sorocarp development;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55DA0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DB0-1", "uniprot_id": [ { "id": "SIR2E_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DB0", "type": "external" } ], "mass": 39579.0, "length": 343, "protein_name": "NAD-dependent deacetylase sir2E", "gene_name": "sir2E", "organism": "Cellular slime mold", "refseq_name": "NAD(+)-dependent deacetylase, silent information regulator protein family protein", "refseq_ac": [ { "id": "XP_646221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646221", "type": "external" } ], "gene_names_uniprotkb": "sir2E; DDB_G0270928", "gene_names_refseq": "sir2E", "protein_names_uniprotkb": "NAD-dependent deacetylase sir2E; 2.3.1.286; Silent information regulator 2E", "protein_names_refseq": "NAD(+)-dependent deacetylase, silent information regulator protein family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270928); (R-DDI-2151201)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;18707607", "class_list": "", "function": "NAD-dependent deacetylase, which plays an important role in the regulation of transcriptional repression (By similarity). May play a role in cell cycle. When overexpressed, the cell cycle is accelerated., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0036054 protein-malonyllysine demalonylase activity;GO:0036055 protein-succinyllysine desuccinylase activity;GO:0061697 protein-glutaryllysine deglutarylase activity;GO:0046872 metal ion binding;GO:0070403 NAD+ binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55DB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DD4-1", "uniprot_id": [ { "id": "PAKD_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DD4", "type": "external" } ], "mass": 190772.0, "length": 1678, "protein_name": "Serine/threonine-protein kinase pakD", "gene_name": "pakD", "organism": "Cellular slime mold", "refseq_name": "PAKA subfamily protein kinase", "refseq_ac": [ { "id": "XP_646197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646197", "type": "external" } ], "gene_names_uniprotkb": "pakD; DDB_G0269696", "gene_names_refseq": "pakD", "protein_names_uniprotkb": "Serine/threonine-protein kinase pakD; 2.7.11.1", "protein_names_refseq": "PAKA subfamily protein kinase; PKC domain-containing protein, PE/DAG binding; STE20 family protein kinase; p21-activated protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269696); (R-DDI-2029482); (R-DDI-389359); (R-DDI-3928662); (R-DDI-445144); (R-DDI-5621575); (R-DDI-5627123); (R-DDI-5687128); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0045499 chemorepellent activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031143 pseudopodium;GO:0001931 uropod;GO:0031254 cell trailing edge", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0030041 actin filament polymerization;GO:0009267 cellular response to starvation;GO:0051490 negative regulation of filopodium assembly;GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55DD4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DD5-1", "uniprot_id": [ { "id": "Q55DD5_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DD5", "type": "external" } ], "mass": 173131.0, "length": 1536, "protein_name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "gene_name": "pan2", "organism": "Cellular slime mold", "refseq_name": "WD40-like domain-containing protein", "refseq_ac": [ { "id": "XP_646196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646196", "type": "external" } ], "gene_names_uniprotkb": "pan2; DDB_G0269694; PAN2", "gene_names_refseq": "pan2", "protein_names_uniprotkb": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2; 3.1.13.4; PAB1P-dependent poly(A)-specific ribonuclease; PAN deadenylation complex subunit 2; Poly(A)-nuclease deadenylation complex subunit 2", "protein_names_refseq": "WD40-like domain-containing protein; peptidase C19 family protein; polyA specific ribonuclease subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269694)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0000932 P-body;GO:0031251 PAN complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006301 DNA damage tolerance;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55DD5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DH8-1", "uniprot_id": [ { "id": "CATB_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DH8", "type": "external" } ], "mass": 78033.0, "length": 692, "protein_name": "Catalase-B", "gene_name": "catB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_646153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646153", "type": "external" } ], "gene_names_uniprotkb": "catB; DDB_G0269108", "gene_names_refseq": "catB", "protein_names_uniprotkb": "Catalase-B; 1.11.1.6", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269108)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11004503;11553701;12788229;15075287;15875012", "class_list": "", "function": "Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Its accumulation in prespore cells affords the spores protection from oxidation during prolonged dormancy. Required for normal developmental timing, possibly through a regulatory role in differentiation and morphogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6TWC1;Q9U6L8", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004096 catalase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0000302 response to reactive oxygen species;GO:0042744 hydrogen peroxide catabolic process;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q55DH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DJ8-1", "uniprot_id": [ { "id": "IRLC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DJ8", "type": "external" } ], "mass": 167425.0, "length": 1444, "protein_name": "Probable serine/threonine-protein kinase irlC", "gene_name": "irlC", "organism": "Cellular slime mold", "refseq_name": "IRE family protein kinase", "refseq_ac": [ { "id": "XP_646133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646133", "type": "external" } ], "gene_names_uniprotkb": "irlC; DDB_G0270894", "gene_names_refseq": "irlC", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase irlC; 2.7.11.1; Inositol-requiring protein-like protein kinase C", "protein_names_refseq": "IRE family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270894); (R-DDI-381070)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0051082 unfolded protein binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006397 mRNA processing;GO:0036498 IRE1-mediated unfolded protein response;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55DJ8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DM1-1", "uniprot_id": [ { "id": "LVSA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DM1", "type": "external" } ], "mass": 408030.0, "length": 3619, "protein_name": "BEACH domain-containing protein lvsA", "gene_name": "lvsA", "organism": "Cellular slime mold", "refseq_name": "BEACH domain-containing protein", "refseq_ac": [ { "id": "XP_646110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646110", "type": "external" } ], "gene_names_uniprotkb": "lvsA; DDB_G0269150", "gene_names_refseq": "lvsA", "protein_names_uniprotkb": "BEACH domain-containing protein lvsA; Large volume sphere mutant protein A", "protein_names_refseq": "BEACH domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269150)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10588668;11865029;11872142;15086784;15875012", "class_list": "", "function": "Involved in myosin-independent cytokinesis and early steps of phagocytosis. Also involved in contractile vacuole-mediated osmoregulation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9U573", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000331 contractile vacuole;GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0006874 intracellular calcium ion homeostasis;GO:0006909 phagocytosis;GO:0007032 endosome organization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q55DM1-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DR6-1", "uniprot_id": [ { "id": "FCSA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DR6", "type": "external" } ], "mass": 74609.0, "length": 667, "protein_name": "Fatty acyl-CoA synthetase A", "gene_name": "fcsA", "organism": "Cellular slime mold", "refseq_name": "fatty acyl-CoA synthetase", "refseq_ac": [ { "id": "XP_646065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646065", "type": "external" } ], "gene_names_uniprotkb": "fcsA; DDB_G0269242", "gene_names_refseq": "fcsA", "protein_names_uniprotkb": "Fatty acyl-CoA synthetase A; 6.2.1.3; LC-FACS 1; Long chain fatty acyl coenzyme A-synthetase 1; Long-chain-fatty-acid--CoA synthetase 1", "protein_names_refseq": "fatty acyl-CoA synthetase; long-chain-fatty-acid-CoA ligase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269242); (R-DDI-2046105); (R-DDI-2046106); (R-DDI-75876)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "14629118;15875012;16926386", "class_list": "", "function": "Long chain fatty acid acyl-CoA synthetases catalyze the formation of a thioester bond between a free fatty acid and coenzyme A during fatty acid metabolic process. May mediate fatty acid retrieval from the lumen of endosomes into the cytoplasm., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86PL9", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004467 long-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0016020 membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55DR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55DV9-1", "uniprot_id": [ { "id": "CGL_DICDI", "url": "https://www.uniprot.org/uniprot/Q55DV9", "type": "external" } ], "mass": 42497.0, "length": 387, "protein_name": "Cystathionine gamma-lyase", "gene_name": "cysA", "organism": "Cellular slime mold", "refseq_name": "cystathionine gamma-lyase", "refseq_ac": [ { "id": "XP_646022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646022", "type": "external" } ], "gene_names_uniprotkb": "cysA; DDB_G0269122", "gene_names_refseq": "cysA", "protein_names_uniprotkb": "Cystathionine gamma-lyase; 4.4.1.1; 4.4.1.2; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase", "protein_names_refseq": "cystathionine gamma-lyase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269122); (R-DDI-1614558); (R-DDI-1614603)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;17259634", "class_list": "", "function": "Catalyzes the last step in the trans-sulfuration pathway from L-methionine to L-cysteine in a pyridoxal-5'-phosphate (PLP)-dependent manner, which consists on cleaving the L,L-cystathionine molecule into L-cysteine, ammonia and 2-oxobutanoate. Part of the L-cysteine derived from the trans-sulfuration pathway is utilized for biosynthesis of the ubiquitous antioxidant glutathione. Besides its role in the conversion of L-cystathionine into L-cysteine, it utilizes L-cysteine and L-homocysteine as substrates (at much lower rates than L,L-cystathionine) to produce the endogenous gaseous signaling molecule hydrogen sulfide (H2S)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.1", "type": "external" }, { "id": "4.4.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.2", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004123 cystathionine gamma-lyase activity;GO:0047982 homocysteine desulfhydrase activity;GO:0080146 L-cysteine desulfhydrase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006534 cysteine metabolic process;GO:0019346 transsulfuration;GO:0019343 cysteine biosynthetic process via cystathionine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55DV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55E26-1", "uniprot_id": [ { "id": "GXCB_DICDI", "url": "https://www.uniprot.org/uniprot/Q55E26", "type": "external" } ], "mass": 134479.0, "length": 1198, "protein_name": "Rac guanine nucleotide exchange factor B", "gene_name": "gxcB", "organism": "Cellular slime mold", "refseq_name": "RhoGEF domain-containing protein", "refseq_ac": [ { "id": "XP_645955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645955", "type": "external" } ], "gene_names_uniprotkb": "gxcB; DDB_G0269424; Trix", "gene_names_refseq": "gxcB", "protein_names_uniprotkb": "Rac guanine nucleotide exchange factor B", "protein_names_refseq": "RhoGEF domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269424)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16781009", "class_list": "", "function": "Involved in the regulation of the late steps of the endocytic pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2MCX4", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005938 cell cortex;GO:0005770 late endosome", "go_biological_process": "GO:0006897 endocytosis;GO:0035556 intracellular signal transduction;GO:0051017 actin filament bundle assembly;GO:0051764 actin crosslink formation;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55E26-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55E54-1", "uniprot_id": [ { "id": "COROB_DICDI", "url": "https://www.uniprot.org/uniprot/Q55E54", "type": "external" } ], "mass": 105955.0, "length": 962, "protein_name": "Coronin-B", "gene_name": "corB", "organism": "Cellular slime mold", "refseq_name": "WD-40 repeat-containing protein", "refseq_ac": [ { "id": "XP_645927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645927", "type": "external" } ], "gene_names_uniprotkb": "corB; DDB_G0269388; cor7", "gene_names_refseq": "corB", "protein_names_uniprotkb": "Coronin-B; Coronin-7; DdCRN7; Doublecoronin", "protein_names_refseq": "WD-40 repeat-containing protein; coronin B; double coronin", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269388)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;20071332", "class_list": "", "function": "Involved in phagocytosis and cell motility. Binds to actin filaments and protects them against depolymerization., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005829 cytosol;GO:0005884 actin filament;GO:0005886 plasma membrane;GO:0031252 cell leading edge", "go_biological_process": "GO:0030835 negative regulation of actin filament depolymerization;GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0006909 phagocytosis;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55E54-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55E58-1", "uniprot_id": [ { "id": "PATS1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55E58", "type": "external" } ], "mass": 356654.0, "length": 3184, "protein_name": "Probable serine/threonine-protein kinase pats1", "gene_name": "pats1", "organism": "Cellular slime mold", "refseq_name": "ROCO family protein kinase", "refseq_ac": [ { "id": "XP_645923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645923", "type": "external" } ], "gene_names_uniprotkb": "pats1; DDB_G0269250", "gene_names_refseq": "pats1", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase pats1; 2.7.11.1; Protein associated with the transduction of signal 1", "protein_names_refseq": "ROCO family protein kinase; WD40 repeat-containing protein; leucine-rich repeat-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269250); (R-DDI-1483248); (R-DDI-1632852); (R-DDI-1660499); (R-DDI-1660516); (R-DDI-1660517); (R-DDI-8876198)", "pathway_count": 7, "publication_count": 3, "publication_id_list": "12529423;15875012;18523161", "class_list": "", "function": "May act as a serine/threonine-protein kinase and guanine-nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8I7W7", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004721 phosphoprotein phosphatase activity;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0042641 actomyosin", "go_biological_process": "GO:0000281 mitotic cytokinesis;GO:0046856 phosphatidylinositol dephosphorylation;GO:0099139 cheating during chimeric sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55E58-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55E68-1", "uniprot_id": [ { "id": "CPSF5_DICDI", "url": "https://www.uniprot.org/uniprot/Q55E68", "type": "external" } ], "mass": 22786.0, "length": 200, "protein_name": "Cleavage and polyadenylation specificity factor subunit 5", "gene_name": "nudt21", "organism": "Cellular slime mold", "refseq_name": "NUDIX hydrolase family protein", "refseq_ac": [ { "id": "XP_645913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645913", "type": "external" } ], "gene_names_uniprotkb": "nudt21; DDB_G0269370; cpsf5", "gene_names_refseq": "", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 5", "protein_names_refseq": "NUDIX hydrolase family protein; cleavage and polyadenylation specificity factor 5-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269370); (R-DDI-9770562)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs. Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function. Binds to chromatin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005849 mRNA cleavage factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0030154 cell differentiation;GO:0051290 protein heterotetramerization;GO:0031124 mRNA 3'-end processing;GO:0110104 mRNA alternative polyadenylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55E68-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55E72-1", "uniprot_id": [ { "id": "PKS1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55E72", "type": "external" } ], "mass": 352195.0, "length": 3147, "protein_name": "Probable polyketide synthase 1", "gene_name": "stlA", "organism": "Cellular slime mold", "refseq_name": "beta-ketoacyl synthase family protein", "refseq_ac": [ { "id": "XP_645909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645909", "type": "external" } ], "gene_names_uniprotkb": "stlA; DDB_G0269364; pks1", "gene_names_refseq": "stlA", "protein_names_uniprotkb": "Probable polyketide synthase 1; Steely1; dipks1", "protein_names_refseq": "beta-ketoacyl synthase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269364); (R-DDI-199220); (R-DDI-75105)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15875012;16906151;17660200", "class_list": "", "function": "Probable polyketide synthase (By similarity). Produces only acylpyrones; in vitro., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.74", "type": "external" } ], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0004312 fatty acid synthase activity;GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0016210 naringenin-chalcone synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0006633 fatty acid biosynthetic process;GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55E72-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55EC7-1", "uniprot_id": [ { "id": "GEFX_DICDI", "url": "https://www.uniprot.org/uniprot/Q55EC7", "type": "external" } ], "mass": 107769.0, "length": 960, "protein_name": "RasGEF domain-containing serine/threonine-protein kinase X", "gene_name": "gefX", "organism": "Cellular slime mold", "refseq_name": "LISK family protein kinase", "refseq_ac": [ { "id": "XP_645854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645854", "type": "external" } ], "gene_names_uniprotkb": "gefX; DDB_G0269298", "gene_names_refseq": "gefX", "protein_names_uniprotkb": "RasGEF domain-containing serine/threonine-protein kinase X; 2.7.11.1; Ras guanine nucleotide exchange factor X; RasGEF domain-containing protein X", "protein_names_refseq": "LISK family protein kinase; RasGEF domain-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269298); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "15875012;16086850", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031143 pseudopodium", "go_biological_process": "GO:0007165 signal transduction;GO:2000145 regulation of cell motility;GO:0007264 small GTPase-mediated signal transduction;GO:1905303 positive regulation of macropinocytosis;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55EC7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55EI0-1", "uniprot_id": [ { "id": "ATE1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55EI0", "type": "external" } ], "mass": 73820.0, "length": 629, "protein_name": "Arginyl-tRNA--protein transferase 1", "gene_name": "ate1", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_647040", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647040", "type": "external" } ], "gene_names_uniprotkb": "ate1; DDB_G0269024", "gene_names_refseq": "ate1", "protein_names_uniprotkb": "Arginyl-tRNA--protein transferase 1; 2.3.2.8; Arginine-tRNA--protein transferase 1; Arginyltransferase 1; R-transferase 1", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269024)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.8", "type": "external" } ], "go_molecular_function": "GO:0004057 arginyl-tRNA--protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031143 pseudopodium", "go_biological_process": "GO:0016477 cell migration;GO:0010498 proteasomal protein catabolic process;GO:0031589 cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55EI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55EK9-1", "uniprot_id": [ { "id": "PDXK_DICDI", "url": "https://www.uniprot.org/uniprot/Q55EK9", "type": "external" } ], "mass": 34319.0, "length": 302, "protein_name": "Pyridoxal kinase", "gene_name": "pykA", "organism": "Cellular slime mold", "refseq_name": "pyridoxal kinase", "refseq_ac": [ { "id": "XP_647011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647011", "type": "external" } ], "gene_names_uniprotkb": "pykA; DDB_G0268628", "gene_names_refseq": "pykA", "protein_names_uniprotkb": "Pyridoxal kinase; 2.7.1.35; Pyridoxine kinase", "protein_names_refseq": "pyridoxal kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268628); (R-DDI-6798695); (R-DDI-964975)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "10930737;15875012", "class_list": "", "function": "Required for synthesis of pyridoxal-5-phosphate from vitamin B6., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GV94", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.5.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.-.-", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008478 pyridoxal kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042816 vitamin B6 metabolic process;GO:0009443 pyridoxal 5'-phosphate salvage;GO:0019954 asexual reproduction;GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55EK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55EL3-1", "uniprot_id": [ { "id": "UCKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55EL3", "type": "external" } ], "mass": 55797.0, "length": 499, "protein_name": "Uridine-cytidine kinase A", "gene_name": "udkA", "organism": "Cellular slime mold", "refseq_name": "uridine kinase", "refseq_ac": [ { "id": "XP_647007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647007", "type": "external" } ], "gene_names_uniprotkb": "udkA; DDB_G0269034; ukuprt", "gene_names_refseq": "udkA", "protein_names_uniprotkb": "Uridine-cytidine kinase A; 2.7.1.48; Cytidine monophosphokinase A; UK-UPRT; Uridine kinase/uracil phosphoribosyltransferase; Uridine monophosphokinase A", "protein_names_refseq": "uridine kinase; uridine phosphokinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269034); (R-DDI-196807); (R-DDI-73614)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "14973196;15875012", "class_list": "", "function": "Catalyzes the conversion of uridine into uridine monophosphate and cytidine into cytidine monophosphate in the pyrimidine salvage pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6S4W3", "ec_number_list": [ { "id": "2.7.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.48", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004849 uridine kinase activity;GO:0043771 cytidine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008655 pyrimidine-containing compound salvage;GO:0044206 UMP salvage;GO:0044211 CTP salvage", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55EL3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55EU7-1", "uniprot_id": [ { "id": "Y8742_DICDI", "url": "https://www.uniprot.org/uniprot/Q55EU7", "type": "external" } ], "mass": 45935.0, "length": 393, "protein_name": "Probable farnesyl diphosphate synthase DDB_G0268742", "gene_name": "DDB_G0268742", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_646923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646923", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0268742", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable farnesyl diphosphate synthase DDB_G0268742; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.10; 2.5.1.1; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Geranyltranstransferase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268742)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a sterol precursor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.1", "type": "external" }, { "id": "2.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.10", "type": "external" }, { "id": "2.5.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.29", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0004161 dimethylallyltranstransferase activity;GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0033384 geranyl diphosphate biosynthetic process;GO:0045337 farnesyl diphosphate biosynthetic process;GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55EU7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55F21-1", "uniprot_id": [ { "id": "AATM_DICDI", "url": "https://www.uniprot.org/uniprot/Q55F21", "type": "external" } ], "mass": 47285.0, "length": 426, "protein_name": "Aspartate aminotransferase, mitochondrial", "gene_name": "aatA", "organism": "Cellular slime mold", "refseq_name": "aspartate aminotransferase", "refseq_ac": [ { "id": "XP_646849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646849", "type": "external" } ], "gene_names_uniprotkb": "aatA; DDB_G0268664", "gene_names_refseq": "aatA", "protein_names_uniprotkb": "Aspartate aminotransferase, mitochondrial; 2.6.1.1; 2.6.1.7; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Transaminase A", "protein_names_refseq": "aspartate aminotransferase; aspartate transaminase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268664); (R-DDI-389661); (R-DDI-8963693); (R-DDI-8964539); (R-DDI-9856872)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.64", "type": "external" }, { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0016212 kynurenine-oxoglutarate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005886 plasma membrane", "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006533 L-aspartate catabolic process;GO:0006536 glutamate metabolic process;GO:0006531 aspartate metabolic process;GO:0006532 aspartate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55F21-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55F37-1", "uniprot_id": [ { "id": "SRFC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55F37", "type": "external" } ], "mass": 117228.0, "length": 1048, "protein_name": "Transcription factor mef2A", "gene_name": "mef2A", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mef2A; DDB_G0268920; sfrC", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor mef2A; Myocyte enhancer factor 2A; Serum factor response C", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268920); (R-DDI-525793)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;23577638", "class_list": "", "function": "Transcription factor that regulates cell differentiation during development. Seems to negatively regulate prestalk gene expression and positively regulate prespore gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010468 regulation of gene expression;GO:0031285 regulation of sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55F37-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55F68-1", "uniprot_id": [ { "id": "CYAD_DICDI", "url": "https://www.uniprot.org/uniprot/Q55F68", "type": "external" } ], "mass": 243012.0, "length": 2123, "protein_name": "Adenylate cyclase, terminal-differentiation specific", "gene_name": "acrA", "organism": "Cellular slime mold", "refseq_name": "adenylate cyclase", "refseq_ac": [ { "id": "XP_647665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647665", "type": "external" } ], "gene_names_uniprotkb": "acrA; DDB_G0267376; acb", "gene_names_refseq": "acrA", "protein_names_uniprotkb": "Adenylate cyclase, terminal-differentiation specific; 4.6.1.1; ACB; ACR; ATP pyrophosphate-lyase; Adenylyl cyclase", "protein_names_refseq": "adenylate cyclase; adenylyl cyclase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267376)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10419694;10556070;11566867;15875012;16952277;9812977", "class_list": "", "function": "Through the production of cAMP, activates cAMP-dependent protein kinases (PKAs), triggering terminal differential and the production of spores., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9U9S7", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016772 transferase activity, transferring phosphorus-containing groups", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0031000 response to caffeine;GO:0010468 regulation of gene expression;GO:0009642 response to light intensity;GO:0000160 phosphorelay signal transduction system", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q55F68-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55F94-1", "uniprot_id": [ { "id": "DLPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55F94", "type": "external" } ], "mass": 100009.0, "length": 880, "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "organism": "Cellular slime mold", "refseq_name": "dynamin like protein", "refseq_ac": [ { "id": "XP_001732949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001732949", "type": "external" } ], "gene_names_uniprotkb": "dlpA; DDB_G0268592; slb233", "gene_names_refseq": "dlpA", "protein_names_uniprotkb": "Dynamin-like protein A; 3.6.5.5", "protein_names_refseq": "dynamin like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268592)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12796308;15470642;15875012;18809930", "class_list": "", "function": "Involved in cytokinesis. May hydrolyze GTP., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B0G0Y6;C7FZW1", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016020 membrane;GO:0032154 cleavage furrow", "go_biological_process": "GO:0030835 negative regulation of actin filament depolymerization;GO:0007015 actin filament organization;GO:0000281 mitotic cytokinesis;GO:0061952 midbody abscission;GO:1905345 protein localization to cleavage furrow", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q55F94-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FG3-1", "uniprot_id": [ { "id": "VP13C_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FG3", "type": "external" } ], "mass": 440005.0, "length": 3848, "protein_name": "Intermembrane lipid transfer protein tipC", "gene_name": "tipC", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_647570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647570", "type": "external" } ], "gene_names_uniprotkb": "tipC; DDB_G0267422; DG1038; vps13C; vps13", "gene_names_refseq": "tipC", "protein_names_uniprotkb": "Intermembrane lipid transfer protein tipC; Developmental gene 1038 protein; Putative vacuolar protein sorting-associated protein 13C", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267422)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10402673;15875012;17659086", "class_list": "", "function": "Mediates the transfer of lipids between membranes at organelle contact sites., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O76737", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0045053 protein retention in Golgi apparatus;GO:0000045 autophagosome assembly;GO:0006869 lipid transport;GO:0016236 macroautophagy;GO:0045324 late endosome to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55FG3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FP0-1", "uniprot_id": [ { "id": "PHG1A_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FP0", "type": "external" } ], "mass": 73365.0, "length": 641, "protein_name": "Putative phagocytic receptor 1a", "gene_name": "phg1a", "organism": "Cellular slime mold", "refseq_name": "TM9 protein A", "refseq_ac": [ { "id": "XP_647493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647493", "type": "external" } ], "gene_names_uniprotkb": "phg1a; DDB_G0267444; phg1", "gene_names_refseq": "phg1a", "protein_names_uniprotkb": "Putative phagocytic receptor 1a", "protein_names_refseq": "TM9 protein A", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267444)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10944536;12857872;15875012;16367873;25999474", "class_list": "", "function": "Involved in adhesion, phagocytosis of hydrophilic particles and intracellular killing of bacteria (PubMed:10944536, PubMed:12857872, PubMed:16367873). Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface (PubMed:25999474)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95ZG2", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0032009 early phagosome", "go_biological_process": "GO:2000010 positive regulation of protein localization to cell surface;GO:0006909 phagocytosis;GO:0050821 protein stabilization;GO:0042742 defense response to bacterium;GO:0072657 protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q55FP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FQ9-1", "uniprot_id": [ { "id": "LMPC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FQ9", "type": "external" } ], "mass": 87876.0, "length": 782, "protein_name": "Lysosome membrane protein 2-C", "gene_name": "lmpC", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_647474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647474", "type": "external" } ], "gene_names_uniprotkb": "lmpC; DDB_G0267440", "gene_names_refseq": "lmpC", "protein_names_uniprotkb": "Lysosome membrane protein 2-C; LIMP II-3; Lysosome membrane protein II-3", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267440); (R-DDI-114608); (R-DDI-434313); (R-DDI-6798695); (R-DDI-8856825)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "11489884;15875012", "class_list": "", "function": "May act as a lysosomal receptor (By similarity). May be involved role in macropinocytosis and fluid phase exocytosis., [UniProtKB]", "predicted_glycosites": 22, "predicted_n_glycosites": 22, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 22, "binding_glycan_count": 0, "secondary_ac_list": "Q9BKJ8", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity", "go_cellular_component": "GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0032010 phagolysosome;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006911 phagocytosis, engulfment", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55FQ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FS0-1", "uniprot_id": [ { "id": "UBA4_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FS0", "type": "external" } ], "mass": 47055.0, "length": 425, "protein_name": "Adenylyltransferase and sulfurtransferase MOCS3", "gene_name": "mocs3", "organism": "Cellular slime mold", "refseq_name": "molybdenum cofactor synthesis 3", "refseq_ac": [ { "id": "XP_647463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647463", "type": "external" } ], "gene_names_uniprotkb": "mocs3; DDB_G0267980; uba4", "gene_names_refseq": "mocs3", "protein_names_uniprotkb": "Adenylyltransferase and sulfurtransferase MOCS3; Adenylyltransferase MOCS3; Molybdenum cofactor synthesis protein 3; Sulfur carrier protein MOCS2A adenylyltransferase; Sulfur carrier protein MOCS2A sulfurtransferase; Sulfurtransferase MOCS3; Ubiquitin-like protein activator 4 homolog", "protein_names_refseq": "molybdenum cofactor synthesis 3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267980); (R-DDI-947581)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as a nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.80", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.80", "type": "external" }, { "id": "2.8.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.11", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016779 nucleotidyltransferase activity;GO:0004792 thiosulfate-cyanide sulfurtransferase activity;GO:0042292 URM1 activating enzyme activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation;GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55FS0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FS2-1", "uniprot_id": [ { "id": "STK4L_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FS2", "type": "external" } ], "mass": 123745.0, "length": 1105, "protein_name": "Serine/threonine-protein kinase 4 homolog B", "gene_name": "krsB", "organism": "Cellular slime mold", "refseq_name": "MST subfamily kinase", "refseq_ac": [ { "id": "XP_647461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647461", "type": "external" } ], "gene_names_uniprotkb": "krsB; DDB_G0267978; krs2", "gene_names_refseq": "krsB", "protein_names_uniprotkb": "Serine/threonine-protein kinase 4 homolog B; 2.7.11.1; Kinase responsive to stress B; STE20-like kinase krsB", "protein_names_refseq": "MST subfamily kinase; STE20 family protein kinase; calpain-like cysteine protease; peptidase C2 family protein; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267978)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Probable serine/threonine-protein kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:1903077 negative regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55FS2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FS3-1", "uniprot_id": [ { "id": "APH1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FS3", "type": "external" } ], "mass": 37605.0, "length": 328, "protein_name": "Gamma-secretase subunit Aph-1", "gene_name": "aph1", "organism": "Cellular slime mold", "refseq_name": "gamma-secretase subunit Aph-1", "refseq_ac": [ { "id": "XP_647460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647460", "type": "external" } ], "gene_names_uniprotkb": "aph1; DDB_G0267976", "gene_names_refseq": "aph1", "protein_names_uniprotkb": "Gamma-secretase subunit Aph-1", "protein_names_refseq": "gamma-secretase subunit Aph-1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267976)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors precursor protein. It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0070765 gamma-secretase complex", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0016485 protein processing;GO:0006909 phagocytosis;GO:0006914 autophagy;GO:0044351 macropinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55FS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FT1-1", "uniprot_id": [ { "id": "DPYD_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FT1", "type": "external" } ], "mass": 110444.0, "length": 1009, "protein_name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "gene_name": "pyd1", "organism": "Cellular slime mold", "refseq_name": "dihydropyrimidine dehydrogenase", "refseq_ac": [ { "id": "XP_647452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647452", "type": "external" } ], "gene_names_uniprotkb": "pyd1; DDB_G0267966", "gene_names_refseq": "pyd1", "protein_names_uniprotkb": "Dihydropyrimidine dehydrogenase [NADP(+)]; 1.3.1.2; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase", "protein_names_refseq": "dihydropyrimidine dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267966); (R-DDI-73621)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5ZQQ8", "ec_number_list": [ { "id": "1.3.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.2", "type": "external" } ], "go_molecular_function": "GO:0002058 uracil binding;GO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006210 thymine catabolic process;GO:0006212 uracil catabolic process;GO:0006214 thymidine catabolic process;GO:0019483 beta-alanine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55FT1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FT4-1", "uniprot_id": [ { "id": "TSUA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FT4", "type": "external" } ], "mass": 252890.0, "length": 2247, "protein_name": "Probable serine/threonine-protein kinase tsuA", "gene_name": "tsuA", "organism": "Cellular slime mold", "refseq_name": "ULK family protein kinase", "refseq_ac": [ { "id": "XP_647449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647449", "type": "external" } ], "gene_names_uniprotkb": "tsuA; DDB_G0267962", "gene_names_refseq": "tsuA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase tsuA; 2.7.11.1; Tsunami", "protein_names_refseq": "ULK family protein kinase; fused-like protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267962)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15473840;15875012;18708585", "class_list": "", "function": "Plays a role in chemotaxis and seems to be involved in polarization., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0007224 smoothened signaling pathway;GO:0030010 establishment of cell polarity;GO:0030837 negative regulation of actin filament polymerization;GO:0031272 regulation of pseudopodium assembly;GO:0043326 chemotaxis to folate", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55FT4-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FT9-1", "uniprot_id": [ { "id": "ABIA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FT9", "type": "external" } ], "mass": 35313.0, "length": 332, "protein_name": "Abl interactor homolog", "gene_name": "abiA", "organism": "Cellular slime mold", "refseq_name": "component of SCAR regulatory complex", "refseq_ac": [ { "id": "XP_647444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647444", "type": "external" } ], "gene_names_uniprotkb": "abiA; DDB_G0267956", "gene_names_refseq": "abiA", "protein_names_uniprotkb": "Abl interactor homolog", "protein_names_refseq": "component of SCAR regulatory complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267956); (R-DDI-2029482); (R-DDI-5663213); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "15875012;17314411;18261908", "class_list": "", "function": "Involved in regulation of actin and microtubule organization. Required for proper cytokinesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0030027 lamellipodium;GO:0031252 cell leading edge;GO:0031209 SCAR complex;GO:0031143 pseudopodium", "go_biological_process": "GO:0046847 filopodium assembly;GO:0045184 establishment of protein localization;GO:0000281 mitotic cytokinesis;GO:0048870 cell motility;GO:0031269 pseudopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55FT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55FX5-1", "uniprot_id": [ { "id": "Q55FX5_DICDI", "url": "https://www.uniprot.org/uniprot/Q55FX5", "type": "external" } ], "mass": 155978.0, "length": 1382, "protein_name": "Phosphatidylinositol 3-kinase", "gene_name": "pikF", "organism": "Cellular slime mold", "refseq_name": "phosphatidylinositol 3-kinase", "refseq_ac": [ { "id": "XP_647408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647408", "type": "external" } ], "gene_names_uniprotkb": "pikF; DDB_G0268548", "gene_names_refseq": "pikF", "protein_names_uniprotkb": "Phosphatidylinositol 3-kinase", "protein_names_refseq": "phosphatidylinositol 3-kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268548); (R-DDI-114604); (R-DDI-1660499); (R-DDI-1660514); (R-DDI-1660516); (R-DDI-1660517); (R-DDI-392451)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0031267 small GTPase binding;GO:0016303 1-phosphatidylinositol-3-kinase activity;GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031252 cell leading edge", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0016477 cell migration;GO:0009617 response to bacterium;GO:0048015 phosphatidylinositol-mediated signaling;GO:0050920 regulation of chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55FX5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55G45-1", "uniprot_id": [ { "id": "GEMA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55G45", "type": "external" } ], "mass": 75140.0, "length": 658, "protein_name": "Probable mitochondrial Rho GTPase gemA", "gene_name": "gemA", "organism": "Cellular slime mold", "refseq_name": "Ras-related GTPase", "refseq_ac": [ { "id": "XP_647338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647338", "type": "external" } ], "gene_names_uniprotkb": "gemA; DDB_G0267830", "gene_names_refseq": "gemA", "protein_names_uniprotkb": "Probable mitochondrial Rho GTPase gemA; 3.6.5.-; Miro", "protein_names_refseq": "Ras-related GTPase; mitochondrial GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267830); (R-DDI-9013418); (R-DDI-9013422)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;16762450", "class_list": "", "function": "Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55G45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55G81-1", "uniprot_id": [ { "id": "ERCC2_DICDI", "url": "https://www.uniprot.org/uniprot/Q55G81", "type": "external" } ], "mass": 88278.0, "length": 776, "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "repD", "organism": "Cellular slime mold", "refseq_name": "transcription factor IIH component", "refseq_ac": [ { "id": "XP_647302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647302", "type": "external" } ], "gene_names_uniprotkb": "repD; DDB_G0267414; ercc2", "gene_names_refseq": "repD", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH helicase subunit XPD; 5.6.2.3; DNA 5'-3' helicase XPD; DNA excision repair cross-complementing protein-2 homolog; DNA repair protein D; TFIIH basal transcription factor complex helicase repD subunit; TFIIH subunit XPD", "protein_names_refseq": "transcription factor IIH component", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267414); (R-DDI-113418); (R-DDI-5696395); (R-DDI-674695); (R-DDI-6781823); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-6796648); (R-DDI-72086); (R-DDI-73772); (R-DDI-73776); (R-DDI-73779); (R-DDI-75953); (R-DDI-76042); (R-DDI-77075)", "pathway_count": 15, "publication_count": 5, "publication_id_list": "11004503;15875012;9171087;9649625;9765592", "class_list": "", "function": "ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CDK-activating kinase (CAK), in transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATP-dependent helicase activity of XPD/repD is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. XPD/repD acts by forming a bridge between CAK and the core-TFIIH complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O00836", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.1.1.56", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.56", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005675 transcription factor TFIIH holo complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0006366 transcription by RNA polymerase II;GO:0006289 nucleotide-excision repair;GO:0045951 positive regulation of mitotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q55G81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55G87-1", "uniprot_id": [ { "id": "CANB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55G87", "type": "external" } ], "mass": 20757.0, "length": 180, "protein_name": "Calcineurin subunit B type 1", "gene_name": "cnbA", "organism": "Cellular slime mold", "refseq_name": "CaM-dependent protein phosphatase, regulatory subunit", "refseq_ac": [ { "id": "XP_001134484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001134484", "type": "external" } ], "gene_names_uniprotkb": "cnbA; DDB_G0267446", "gene_names_refseq": "cnbA", "protein_names_uniprotkb": "Calcineurin subunit B type 1; Calcineurin regulatory subunit 1; Protein phosphatase 2B regulatory subunit 1", "protein_names_refseq": "CaM-dependent protein phosphatase, regulatory subunit; calcineurin B; protein phosphatase 2B; protein serine/threonine phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267446)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11352578;15875012;16512895", "class_list": "", "function": "Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase (PubMed:11352578). Confers calcium sensitivity (PubMed:11352578). Important for stalk formation (PubMed:16512895)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55G86;Q9GP83", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0019903 protein phosphatase binding;GO:0019902 phosphatase binding;GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity", "go_cellular_component": "GO:0005955 calcineurin complex", "go_biological_process": "GO:0097720 calcineurin-mediated signaling;GO:0043157 response to cation stress;GO:0031287 positive regulation of sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55G87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GE2-1", "uniprot_id": [ { "id": "ODC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GE2", "type": "external" } ], "mass": 32388.0, "length": 300, "protein_name": "Probable mitochondrial 2-oxodicarboxylate carrier", "gene_name": "mcfT", "organism": "Cellular slime mold", "refseq_name": "mitochondrial 2-oxodicarboxylate carrier protein", "refseq_ac": [ { "id": "XP_647242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647242", "type": "external" } ], "gene_names_uniprotkb": "mcfT; DDB_G0267704; slc25a21", "gene_names_refseq": "mcfT", "protein_names_uniprotkb": "Probable mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21", "protein_names_refseq": "mitochondrial 2-oxodicarboxylate carrier protein; mitochondrial substrate carrier family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267704); (R-DDI-71064)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;17442478", "class_list": "", "function": "Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism. Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate. Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005310 dicarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GF9-1", "uniprot_id": [ { "id": "ICPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GF9", "type": "external" } ], "mass": 152366.0, "length": 1320, "protein_name": "Inner centromere protein A", "gene_name": "icpA", "organism": "Cellular slime mold", "refseq_name": "inner centromere protein, ARK binding region family protein", "refseq_ac": [ { "id": "XP_647225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647225", "type": "external" } ], "gene_names_uniprotkb": "icpA; DDB_G0267690; Incenp", "gene_names_refseq": "icpA", "protein_names_uniprotkb": "Inner centromere protein A; DdINCENP", "protein_names_refseq": "inner centromere protein, ARK binding region family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267690)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;16339076;16512674", "class_list": "", "function": "Chromosomal passenger protein that seems to be required for chromosome segregation and the onset of cytokinesis during mitosis. Plays a key role in the abscission of daughter cells at the end of cytokinesis and in the establishment or maintenance of a bipolar spindle., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005819 spindle;GO:0000775 chromosome, centromeric region;GO:0032154 cleavage furrow", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0009612 response to mechanical stimulus;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55GF9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GH4-1", "uniprot_id": [ { "id": "GYS_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GH4", "type": "external" } ], "mass": 97515.0, "length": 878, "protein_name": "Glycogen [starch] synthase", "gene_name": "glcS", "organism": "Cellular slime mold", "refseq_name": "glycogen synthase", "refseq_ac": [ { "id": "XP_647210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647210", "type": "external" } ], "gene_names_uniprotkb": "glcS; DDB_G0267674", "gene_names_refseq": "glcS", "protein_names_uniprotkb": "Glycogen [starch] synthase; 2.4.1.11", "protein_names_refseq": "glycogen synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267674)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;9023987", "class_list": "glycogene;glycosyltransferase", "function": "Catalyzes the formation of apha-1,4 glycosidic bonds adding glucose residue from UDPG to the growing chain of glycogen., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.11", "type": "external" } ], "go_molecular_function": "GO:0004373 alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0005978 glycogen biosynthetic process;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GH4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GJ2-1", "uniprot_id": [ { "id": "IREA_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GJ2", "type": "external" } ], "mass": 112801.0, "length": 984, "protein_name": "Probable serine/threonine-protein kinase ireA", "gene_name": "ireA", "organism": "Cellular slime mold", "refseq_name": "IRE family protein kinase", "refseq_ac": [ { "id": "XP_647192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647192", "type": "external" } ], "gene_names_uniprotkb": "ireA; DDB_G0267650", "gene_names_refseq": "ireA", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase ireA; 2.7.11.1; Inositol-requiring protein A", "protein_names_refseq": "IRE family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267650); (R-DDI-381070)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0004521 RNA endonuclease activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006020 inositol metabolic process;GO:1903894 regulation of IRE1-mediated unfolded protein response;GO:0006397 mRNA processing;GO:0006468 protein phosphorylation;GO:0036498 IRE1-mediated unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q55GJ2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GJ6-1", "uniprot_id": [ { "id": "PSB6_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GJ6", "type": "external" } ], "mass": 23446.0, "length": 214, "protein_name": "Proteasome subunit beta type-6", "gene_name": "psmB6", "organism": "Cellular slime mold", "refseq_name": "20S proteasome subunit beta-6", "refseq_ac": [ { "id": "XP_647188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647188", "type": "external" } ], "gene_names_uniprotkb": "psmB6; DDB_G0267390; dapA", "gene_names_refseq": "psmB6", "protein_names_uniprotkb": "Proteasome subunit beta type-6; 3.4.25.1; DAPS-1; Differentiation-associated proteasome subunit 1", "protein_names_refseq": "20S proteasome subunit beta-6; proteasome subunit beta type 6", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267390); (R-DDI-1236974); (R-DDI-1236978); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-187577); (R-DDI-2467813); (R-DDI-349425); (R-DDI-382556); (R-DDI-450408); (R-DDI-4641258); (R-DDI-5632684); (R-DDI-5658442); (R-DDI-5687128); (R-DDI-5689603); (R-DDI-5689880); (R-DDI-68949); (R-DDI-69017); (R-DDI-69601); (R-DDI-75815); (R-DDI-8854050); (R-DDI-8948751); (R-DDI-8951664); (R-DDI-9755511); (R-DDI-983168); (R-DDI-9907900); (R-DDI-9912633); (R-DDI-9929491); (R-DDI-9954709)", "pathway_count": 30, "publication_count": 3, "publication_id_list": "15875012;8130037;9535814", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O60953", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55GJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GK8-1", "uniprot_id": [ { "id": "KIL1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GK8", "type": "external" } ], "mass": 55568.0, "length": 471, "protein_name": "Membrane-associated sulfotransferase kil1", "gene_name": "kil1", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_647176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647176", "type": "external" } ], "gene_names_uniprotkb": "kil1; DDB_G0267630", "gene_names_refseq": "kil1", "protein_names_uniprotkb": "Membrane-associated sulfotransferase kil1; 2.8.2.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267630)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;16367873", "class_list": "", "function": "Sulfotransferase involved in intracellular killing of bacteria., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008146 sulfotransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0001878 response to yeast;GO:0050829 defense response to Gram-negative bacterium;GO:0042742 defense response to bacterium;GO:0140460 response to Gram-negative bacterium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GK8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GN6-1", "uniprot_id": [ { "id": "Y7588_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GN6", "type": "external" } ], "mass": 80506.0, "length": 719, "protein_name": "Probable phosphatidylinositol phosphate kinase DDB_G0267588", "gene_name": "DDB_G0267588", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_647148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647148", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0267588", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable phosphatidylinositol phosphate kinase DDB_G0267588; 2.7.1.-", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267588); (R-DDI-1660499); (R-DDI-6811555); (R-DDI-6811558); (R-DDI-8847453); (R-DDI-8856828)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "15875012;18635356", "class_list": "", "function": "May be involved in signaling events that underlie chemotaxis via the chemoattractant-mediated pkgB phosphorylation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" }, { "id": "2.7.1.149", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.149", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0019887 protein kinase regulator activity;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0052742 phosphatidylinositol kinase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0046578 regulation of Ras protein signal transduction;GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GN6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GQ5-1", "uniprot_id": [ { "id": "SODC1_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GQ5", "type": "external" } ], "mass": 15856.0, "length": 153, "protein_name": "Superoxide dismutase [Cu-Zn] 1", "gene_name": "sodA", "organism": "Cellular slime mold", "refseq_name": "superoxide dismutase", "refseq_ac": [ { "id": "XP_647129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647129", "type": "external" } ], "gene_names_uniprotkb": "sodA; DDB_G0267420", "gene_names_refseq": "sodA", "protein_names_uniprotkb": "Superoxide dismutase [Cu-Zn] 1; 1.15.1.1", "protein_names_refseq": "superoxide dismutase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267420); (R-DDI-114608); (R-DDI-3299685)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "11004503;12186757;15875012", "class_list": "", "function": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O77243", "ec_number_list": [ { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "1.15.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.15.1.1", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004784 superoxide dismutase activity", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:1904643 response to curcumin;GO:0006979 response to oxidative stress;GO:0009617 response to bacterium;GO:0042542 response to hydrogen peroxide;GO:0046686 response to cadmium ion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q55GQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GS3-1", "uniprot_id": [ { "id": "DICB_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GS3", "type": "external" } ], "mass": 65169.0, "length": 607, "protein_name": "Discoidin-inducing complex subunit B", "gene_name": "dicB", "organism": "Cellular slime mold", "refseq_name": "discoidin-inducing complex protein", "refseq_ac": [ { "id": "XP_647111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647111", "type": "external" } ], "gene_names_uniprotkb": "dicB; DDB_G0267470", "gene_names_refseq": "dicB", "protein_names_uniprotkb": "Discoidin-inducing complex subunit B", "protein_names_refseq": "discoidin-inducing complex protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267470)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;15947191", "class_list": "", "function": "Component of a complex that acts as a quorum sensing protein regulating discoidin gene expression during growth and development. Its function in the complex is unclear as it has no ability to induce discoidin during growth and development by itself., [UniProtKB]", "predicted_glycosites": 10, "predicted_n_glycosites": 10, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "Q7YZT1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GV3-1", "uniprot_id": [ { "id": "PAKC_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GV3", "type": "external" } ], "mass": 54177.0, "length": 477, "protein_name": "Serine/threonine-protein kinase pakC", "gene_name": "pakC", "organism": "Cellular slime mold", "refseq_name": "PAKA subfamily protein kinase", "refseq_ac": [ { "id": "XP_647081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647081", "type": "external" } ], "gene_names_uniprotkb": "pakC; DDB_G0267450", "gene_names_refseq": "pakC", "protein_names_uniprotkb": "Serine/threonine-protein kinase pakC; 2.7.11.1; dPAKc", "protein_names_refseq": "PAKA subfamily protein kinase; PH domain-containing protein; STE20 family protein kinase; p21-activated protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267450); (R-DDI-2029482); (R-DDI-389359); (R-DDI-3928662); (R-DDI-445144); (R-DDI-5621575); (R-DDI-5627123); (R-DDI-5687128); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "15483055;15875012", "class_list": "", "function": "Has role in the regulation of chemotaxis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9NAY0", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0046872 metal ion binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000281 mitotic cytokinesis;GO:0009267 cellular response to starvation;GO:0007163 establishment or maintenance of cell polarity;GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GV3-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q55GV9-1", "uniprot_id": [ { "id": "LIMCH_DICDI", "url": "https://www.uniprot.org/uniprot/Q55GV9", "type": "external" } ], "mass": 76480.0, "length": 686, "protein_name": "Calponin homology and LIM domain-containing protein", "gene_name": "ChLim", "organism": "Cellular slime mold", "refseq_name": "LIM-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_647075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647075", "type": "external" } ], "gene_names_uniprotkb": "ChLim; DDB_G0267490", "gene_names_refseq": "ChLim", "protein_names_uniprotkb": "Calponin homology and LIM domain-containing protein; CH-LIM", "protein_names_refseq": "LIM-type zinc finger-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267490); (R-DDI-446353)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15875012;15962002", "class_list": "", "function": "Involved in the regulation of phagocytosis. May repress rab21., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0045335 phagocytic vesicle;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0046847 filopodium assembly;GO:0006909 phagocytosis;GO:0050765 negative regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q55GV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5FXM5-1", "uniprot_id": [ { "id": "ACBP_DICDI", "url": "https://www.uniprot.org/uniprot/Q5FXM5", "type": "external" } ], "mass": 9431.0, "length": 84, "protein_name": "Acyl-CoA-binding protein", "gene_name": "acbA", "organism": "Cellular slime mold", "refseq_name": "acyl-CoA binding protein", "refseq_ac": [ { "id": "XP_646321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646321", "type": "external" } ], "gene_names_uniprotkb": "acbA; DDB_G0270658", "gene_names_refseq": "acbA", "protein_names_uniprotkb": "Acyl-CoA-binding protein; ACBP", "protein_names_refseq": "acyl-CoA binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0270658); (R-DDI-77289)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10373524;15875012;15897458;16672332;9473320", "class_list": "", "function": "Binds to acyl-CoA. Processed into the SDF-2 (spore differentiation factor 2) a peptide which triggers sporulation. SDF-2 appears to stimulate prestalk cells to release additional SDF-2 by acting through a signal transduction pathway that also involves dhkA, regA and PKA. Induces encapsulation of prespore cells in a dhkA-dependent manner. GABA induces the release of acbA from prespore cells and induces the exposure of tagC on the surface of prestalk cells where it can convert acbA to SDF-2. Glutamate acts as a competitive inhibitor and is also able to inhibit induction of sporulation by SDF-2., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55D10", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0000062 fatty-acyl-CoA binding;GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005938 cell cortex;GO:0031982 vesicle", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0016485 protein processing;GO:0030154 cell differentiation;GO:0006974 DNA damage response;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q5FXM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5TJ56-1", "uniprot_id": [ { "id": "FORF_DICDI", "url": "https://www.uniprot.org/uniprot/Q5TJ56", "type": "external" } ], "mass": 135806.0, "length": 1220, "protein_name": "Formin-F", "gene_name": "forF", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_636106", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636106", "type": "external" } ], "gene_names_uniprotkb": "forF; DDB_G0289763; drf1", "gene_names_refseq": "forF", "protein_names_uniprotkb": "Formin-F; Diaphanous-related formin dia1", "protein_names_refseq": "actin binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289763)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15507682;15726806;15740615;15875012;16762450", "class_list": "", "function": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54H12", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0031143 pseudopodium", "go_biological_process": "GO:0070060 'de novo' actin filament nucleation;GO:0030041 actin filament polymerization;GO:0009642 response to light intensity;GO:0046956 positive phototaxis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q5TJ56-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5TJ57-1", "uniprot_id": [ { "id": "FORE_DICDI", "url": "https://www.uniprot.org/uniprot/Q5TJ57", "type": "external" } ], "mass": 174238.0, "length": 1561, "protein_name": "Formin-E", "gene_name": "forE", "organism": "Cellular slime mold", "refseq_name": "actin binding protein", "refseq_ac": [ { "id": "XP_646127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646127", "type": "external" } ], "gene_names_uniprotkb": "forE; DDB_G0269626; dia3; drf3", "gene_names_refseq": "forE", "protein_names_uniprotkb": "Formin-E; Diaphanous-related formin dia3", "protein_names_refseq": "actin binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269626)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15726806;15740615;15875012;16762450", "class_list": "", "function": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55DK4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0005522 profilin binding", "go_cellular_component": "GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0032433 filopodium tip;GO:0031254 cell trailing edge", "go_biological_process": "GO:0070060 'de novo' actin filament nucleation;GO:0030866 cortical actin cytoskeleton organization;GO:0000281 mitotic cytokinesis;GO:0030041 actin filament polymerization;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q5TJ57-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5TJ65-1", "uniprot_id": [ { "id": "VASP_DICDI", "url": "https://www.uniprot.org/uniprot/Q5TJ65", "type": "external" } ], "mass": 39107.0, "length": 380, "protein_name": "Protein VASP homolog", "gene_name": "vasp", "organism": "Cellular slime mold", "refseq_name": "vasodilator-stimulated phosphoprotein", "refseq_ac": [ { "id": "XP_636196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636196", "type": "external" } ], "gene_names_uniprotkb": "vasp; DDB_G0289541", "gene_names_refseq": "vasP", "protein_names_uniprotkb": "Protein VASP homolog; DdVASP", "protein_names_refseq": "vasodilator-stimulated phosphoprotein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289541); (R-DDI-446353); (R-DDI-5658442)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12388544;15875012;16675552", "class_list": "", "function": "Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as lamellipodial and filopodial dynamics in migrating cells. Plays a crucial role in filopodia formation, cell-substratum adhesion, and proper chemotaxis. Nucleates and bundles actin filaments. When complexed with fotH in filopodial tips, may support formin-mediated filament elongation by bundling nascent actin filaments., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q54HE2", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0031252 cell leading edge", "go_biological_process": "GO:0050922 negative regulation of chemotaxis;GO:0072697 protein localization to cell cortex;GO:0006911 phagocytosis, engulfment;GO:0007015 actin filament organization;GO:0046847 filopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5TJ65-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5VJL3-1", "uniprot_id": [ { "id": "GDT9_DICDI", "url": "https://www.uniprot.org/uniprot/Q5VJL3", "type": "external" } ], "mass": 175900.0, "length": 1577, "protein_name": "Probable serine/threonine-protein kinase gdt9", "gene_name": "gdt9", "organism": "Cellular slime mold", "refseq_name": "GDT family protein kinase", "refseq_ac": [ { "id": "XP_001134573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001134573", "type": "external" } ], "gene_names_uniprotkb": "gdt9; DDB_G0278879", "gene_names_refseq": "gdt9", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase gdt9; 2.7.11.1; Growth-differentiation transition protein 9; Protein kinase Dusty", "protein_names_refseq": "GDT family protein kinase; dusty protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278879)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1ZXI4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0050793 regulation of developmental process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5VJL3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5XM24-1", "uniprot_id": [ { "id": "APRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q5XM24", "type": "external" } ], "mass": 55402.0, "length": 494, "protein_name": "Autocrine proliferation repressor protein A", "gene_name": "aprA", "organism": "Cellular slime mold", "refseq_name": "PhoPQ-activated pathogenicity-related protein", "refseq_ac": [ { "id": "XP_640566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640566", "type": "external" } ], "gene_names_uniprotkb": "aprA; DDB_G0281663", "gene_names_refseq": "aprA", "protein_names_uniprotkb": "Autocrine proliferation repressor protein A; PhoPQ-activated pathogenicity-related protein", "protein_names_refseq": "PhoPQ-activated pathogenicity-related protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281663)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15875012;16176950;18550798;18559084;18611962;19187549", "class_list": "", "function": "Inhibitor that slows proliferation of secreting cells (also known as chalone). May function by binding to cell surface receptors. Requires cfaD for activity. Overexpression slows proliferation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q54TM5", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0008233 peptidase activity;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0032991 protein-containing complex", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0072659 protein localization to plasma membrane;GO:0050919 negative chemotaxis;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0031158 negative regulation of aggregate size involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q5XM24-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6B516-1", "uniprot_id": [ { "id": "SPHKB_DICDI", "url": "https://www.uniprot.org/uniprot/Q6B516", "type": "external" } ], "mass": 83966.0, "length": 760, "protein_name": "Sphingosine kinase B", "gene_name": "sgkB", "organism": "Cellular slime mold", "refseq_name": "sphingosine kinase", "refseq_ac": [ { "id": "XP_638540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638540", "type": "external" } ], "gene_names_uniprotkb": "sgkB; DDB_G0284545; SK; SPHK", "gene_names_refseq": "sgkB", "protein_names_uniprotkb": "Sphingosine kinase B; 2.7.1.91; SK B; SPK B", "protein_names_refseq": "sphingosine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284545); (R-DDI-1660661); (R-DDI-390471); (R-DDI-5218921); (R-DDI-9009391); (R-DDI-9833482)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "15643073;15875012", "class_list": "", "function": "Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), which probably acts intracellularly as a second messenger perhaps by promoting cell proliferation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54PJ2", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.91", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.91", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008481 sphingosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0046512 sphingosine biosynthetic process;GO:0006648 dihydrosphingosine-1-P pathway;GO:1903666 positive regulation of asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6B516-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6B9X6-1", "uniprot_id": [ { "id": "VWKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q6B9X6", "type": "external" } ], "mass": 70158.0, "length": 625, "protein_name": "Alpha-protein kinase vwkA", "gene_name": "vwkA", "organism": "Cellular slime mold", "refseq_name": "Alpha kinase family protein", "refseq_ac": [ { "id": "XP_647583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647583", "type": "external" } ], "gene_names_uniprotkb": "vwkA; DDB_G0268144", "gene_names_refseq": "vwkA", "protein_names_uniprotkb": "Alpha-protein kinase vwkA; 2.7.11.1; vWF kinase; von Willebrand factor A alpha-kinase", "protein_names_refseq": "Alpha kinase family protein; protein kinase, Atypical group; protein serine/threonine kinase; type A von Willebrand factor domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268144)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15728726;15875012;17897809;18381083", "class_list": "", "function": "Displays a modest preference for threonine over serine residues. Does not phosphorylate myosin II, however can phosphorylate MBP, in vitro. May be involved in the regulation of myosin II function during cytokinesis. Overexpression leads to impaired cell proliferation in suspension culture and fails to develop beyond the mound stage. Both overexpression and absence of the gene can result in defects in cytokinesis and alterations in myosin II abundance and assembly., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55FF0", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0000331 contractile vacuole;GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0000281 mitotic cytokinesis;GO:0006971 hypotonic response;GO:0031038 myosin II filament organization;GO:0031156 regulation of sorocarp development;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6B9X6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6IMN8-1", "uniprot_id": [ { "id": "ALRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q6IMN8", "type": "external" } ], "mass": 33649.0, "length": 297, "protein_name": "Aldose reductase A", "gene_name": "alrA", "organism": "Cellular slime mold", "refseq_name": "aldehyde reductase", "refseq_ac": [ { "id": "XP_628918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628918", "type": "external" } ], "gene_names_uniprotkb": "alrA; DDB_G0293850", "gene_names_refseq": "alrA", "protein_names_uniprotkb": "Aldose reductase A; 1.1.1.21; ARA; Aldehyde reductase A; AlrA", "protein_names_refseq": "aldehyde reductase; aldo-keto reductase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293850); (R-DDI-156590); (R-DDI-193144); (R-DDI-193368); (R-DDI-193775); (R-DDI-193807); (R-DDI-196108); (R-DDI-2162123); (R-DDI-5365859); (R-DDI-5652227); (R-DDI-5661270); (R-DDI-70221); (R-DDI-9757110)", "pathway_count": 13, "publication_count": 2, "publication_id_list": "14551196;15875012", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies (PubMed:14551196). Probably affects several metabolic pathways in addition to converting glucose to sorbitol (PubMed:14551196). Affects group size (PubMed:14551196)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54B70", "ec_number_list": [ { "id": "1.1.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.21", "type": "external" } ], "go_molecular_function": "GO:0004032 aldose reductase (NADPH) activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0009617 response to bacterium;GO:0042593 glucose homeostasis;GO:0009306 protein secretion;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6IMN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6RZZ9-1", "uniprot_id": [ { "id": "KIF13_DICDI", "url": "https://www.uniprot.org/uniprot/Q6RZZ9", "type": "external" } ], "mass": 142748.0, "length": 1265, "protein_name": "Kinesin-related protein 13", "gene_name": "kif13", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 13", "refseq_ac": [ { "id": "XP_636780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636780", "type": "external" } ], "gene_names_uniprotkb": "kif13; DDB_G0288361", "gene_names_refseq": "kif13", "protein_names_uniprotkb": "Kinesin-related protein 13; Kinesin family member 13; Kinesin-5", "protein_names_refseq": "kinesin family member 13", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288361); (R-DDI-983189)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14641909;15875012;16512674;18712789", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with dynein to control the spindle elongation rate, but is dispensable for mitosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54J21", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005876 spindle microtubule;GO:0072686 mitotic spindle", "go_biological_process": "GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007018 microtubule-based movement;GO:0007051 spindle organization;GO:0051231 spindle elongation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6RZZ9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6S000-1", "uniprot_id": [ { "id": "KIF12_DICDI", "url": "https://www.uniprot.org/uniprot/Q6S000", "type": "external" } ], "mass": 168307.0, "length": 1499, "protein_name": "Kinesin-related protein 12", "gene_name": "kif12", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 12", "refseq_ac": [ { "id": "XP_647633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647633", "type": "external" } ], "gene_names_uniprotkb": "kif12; DDB_G0268258", "gene_names_refseq": "kif12", "protein_names_uniprotkb": "Kinesin-related protein 12; Kinesin family member 12; Kinesin-6", "protein_names_refseq": "kinesin family member 12", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0268258); (R-DDI-68884)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14641909;15546981;15875012;18326585", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Required for cytokinesis. May be involved in a vesicle-mediated transport of myosin II, the Aurora kinase (aurK) and other proteins along mitotic extracellular microtubules toward the center of the cell and the cleavage furrow in order to ensure cell division coupled to mitosis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q55FA0", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0015031 protein transport;GO:0009612 response to mechanical stimulus;GO:0000281 mitotic cytokinesis;GO:0007018 microtubule-based movement;GO:0000912 assembly of actomyosin apparatus involved in cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6S000-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6S001-1", "uniprot_id": [ { "id": "KIF11_DICDI", "url": "https://www.uniprot.org/uniprot/Q6S001", "type": "external" } ], "mass": 75439.0, "length": 685, "protein_name": "Kinesin-related protein 11", "gene_name": "kif11", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 11", "refseq_ac": [ { "id": "XP_635435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635435", "type": "external" } ], "gene_names_uniprotkb": "kif11; DDB_G0291039", "gene_names_refseq": "kif11", "protein_names_uniprotkb": "Kinesin-related protein 11; Kinesin family member 11; Kinesin-7", "protein_names_refseq": "kinesin family member 11", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291039)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14641909;15875012", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54FA2", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0005876 spindle microtubule;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6S001-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6S002-1", "uniprot_id": [ { "id": "KIF10_DICDI", "url": "https://www.uniprot.org/uniprot/Q6S002", "type": "external" } ], "mass": 139012.0, "length": 1238, "protein_name": "Kinesin-related protein 10", "gene_name": "kif10", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 10", "refseq_ac": [ { "id": "XP_629230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629230", "type": "external" } ], "gene_names_uniprotkb": "kif10; DDB_G0293198", "gene_names_refseq": "kif10", "protein_names_uniprotkb": "Kinesin-related protein 10; Kinesin family member 10; Kinesin-8", "protein_names_refseq": "kinesin family member 10", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293198)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14641909;15875012;18430243", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with kif8 and dynein to organize interphase microtubules., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54C36", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005871 kinesin complex;GO:0005876 spindle microtubule;GO:0061673 mitotic spindle astral microtubule", "go_biological_process": "GO:0051301 cell division;GO:0007018 microtubule-based movement;GO:0007019 microtubule depolymerization;GO:0000070 mitotic sister chromatid segregation;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6S002-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6S003-1", "uniprot_id": [ { "id": "KIF8_DICDI", "url": "https://www.uniprot.org/uniprot/Q6S003", "type": "external" } ], "mass": 208948.0, "length": 1873, "protein_name": "Kinesin-related protein 8", "gene_name": "kif8", "organism": "Cellular slime mold", "refseq_name": "WD40 repeat-containing protein", "refseq_ac": [ { "id": "XP_638546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638546", "type": "external" } ], "gene_names_uniprotkb": "kif8; DDB_G0284471; K8; ksnH", "gene_names_refseq": "kif8", "protein_names_uniprotkb": "Kinesin-related protein 8; Kinesin family member 8; Kinesin-4", "protein_names_refseq": "WD40 repeat-containing protein; kinesin family member 8", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284471); (R-DDI-5610787)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14641909;15875012;18430243;9693369", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with kif10 and dynein to organize interphase microtubules., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q54PI6;Q94500", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0051301 cell division;GO:0007018 microtubule-based movement;GO:0000226 microtubule cytoskeleton organization;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6S003-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6S004-1", "uniprot_id": [ { "id": "KIF6_DICDI", "url": "https://www.uniprot.org/uniprot/Q6S004", "type": "external" } ], "mass": 118658.0, "length": 1030, "protein_name": "Kinesin-related protein 6", "gene_name": "kif6", "organism": "Cellular slime mold", "refseq_name": "SAM domain-containing protein", "refseq_ac": [ { "id": "XP_647667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647667", "type": "external" } ], "gene_names_uniprotkb": "kif6; DDB_G0267404; K6; ksnF", "gene_names_refseq": "kif6", "protein_names_uniprotkb": "Kinesin-related protein 6; Kinesin family member 6; Kinesin-13", "protein_names_refseq": "SAM domain-containing protein; kinesin family member 6", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267404)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14641909;15875012;9693369", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55F66;Q94499", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005874 microtubule", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0007019 microtubule depolymerization;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6S004-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6T486-1", "uniprot_id": [ { "id": "RBRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q6T486", "type": "external" } ], "mass": 60553.0, "length": 520, "protein_name": "Probable E3 ubiquitin-protein ligase rbrA", "gene_name": "rbrA", "organism": "Cellular slime mold", "refseq_name": "C3HC4-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_637482", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637482", "type": "external" } ], "gene_names_uniprotkb": "rbrA; DDB_G0286961", "gene_names_refseq": "rbrA", "protein_names_uniprotkb": "Probable E3 ubiquitin-protein ligase rbrA; 2.3.2.31; Ariadne-like ubiquitin ligase", "protein_names_refseq": "C3HC4-type zinc finger-containing protein; IBR zinc finger-containing protein; ariadne-like ubiquitin ligase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286961); (R-DDI-1169408); (R-DDI-983168); (R-DDI-9833482); (R-DDI-9909505)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15875012;17031003", "class_list": "", "function": "Might act as an E3 ubiquitin-protein ligase. Appears to be required for normal cell-type proportioning and cell sorting during multicellular development. In addition to being necessary for a normal percentage of prestalk cells and the organization of the slug, rbrA is also necessary for spore cell viability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54L21", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0031149 sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6T486-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6TMK4-1", "uniprot_id": [ { "id": "POXA_DICDI", "url": "https://www.uniprot.org/uniprot/Q6TMK4", "type": "external" } ], "mass": 60797.0, "length": 531, "protein_name": "Peroxinectin A", "gene_name": "poxA", "organism": "Cellular slime mold", "refseq_name": "animal heme peroxidase family protein", "refseq_ac": [ { "id": "XP_642775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642775", "type": "external" } ], "gene_names_uniprotkb": "poxA; DDB_G0277275", "gene_names_refseq": "poxA", "protein_names_uniprotkb": "Peroxinectin A; 1.11.2.-; DdPoxA; Heme peroxidase", "protein_names_refseq": "animal heme peroxidase family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277275); (R-DDI-6798695); (R-DDI-8941413)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "12097910;15075287;15875012;17950724;29242189", "class_list": "", "function": "Secreted heme peroxidase, able to efficiently oxidize iodide and thiocyanate (PubMed:29242189). Restricts bacterial contamination of fruiting bodies (PubMed:29242189)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q54ZU1", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.51", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.24", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.22", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.2.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.52", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.5.2.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.17", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "6.3.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0020037 heme binding;GO:0036393 thiocyanate peroxidase activity;GO:0004601 peroxidase activity;GO:0004447 iodide peroxidase activity;GO:0140825 lactoperoxidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006955 immune response;GO:0006979 response to oxidative stress;GO:0042742 defense response to bacterium;GO:0042744 hydrogen peroxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q6TMK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.1000000000000.100.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6TU48-1", "uniprot_id": [ { "id": "MAOX_DICDI", "url": "https://www.uniprot.org/uniprot/Q6TU48", "type": "external" } ], "mass": 60652.0, "length": 544, "protein_name": "NADP-dependent malic enzyme", "gene_name": "malA", "organism": "Cellular slime mold", "refseq_name": "NADP malic enzyme", "refseq_ac": [ { "id": "XP_645111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645111", "type": "external" } ], "gene_names_uniprotkb": "malA; DDB_G0272524; sigA", "gene_names_refseq": "malA", "protein_names_uniprotkb": "NADP-dependent malic enzyme; 1.1.1.40; NADP-ME; SrfA-induced gene A protein", "protein_names_refseq": "NADP malic enzyme; NADP-dependent malate dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272524)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;14665466;15075287;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q559J5;Q7KWU9", "ec_number_list": [ { "id": "1.1.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.40", "type": "external" }, { "id": "3.7.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.7.1.5", "type": "external" }, { "id": "4.1.1.112", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.112", "type": "external" } ], "go_molecular_function": "GO:0008948 oxaloacetate decarboxylase activity;GO:0046872 metal ion binding;GO:0051287 NAD binding;GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0004470 malic enzyme activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6TU48-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6UK63-1", "uniprot_id": [ { "id": "PIRA_DICDI", "url": "https://www.uniprot.org/uniprot/Q6UK63", "type": "external" } ], "mass": 153205.0, "length": 1336, "protein_name": "Protein pirA", "gene_name": "pirA", "organism": "Cellular slime mold", "refseq_name": "component of SCAR regulatory complex", "refseq_ac": [ { "id": "XP_637067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637067", "type": "external" } ], "gene_names_uniprotkb": "pirA; DDB_G0287855; pir121", "gene_names_refseq": "pirA", "protein_names_uniprotkb": "Protein pirA", "protein_names_refseq": "component of SCAR regulatory complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287855); (R-DDI-2029482); (R-DDI-5663213); (R-DDI-6798695); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 7, "publication_count": 3, "publication_id_list": "12956949;15875012;16581519", "class_list": "", "function": "Involved in regulation of actin and microtubule organization., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0000340 RNA 7-methylguanosine cap binding", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0031252 cell leading edge;GO:0031209 SCAR complex;GO:0031143 pseudopodium;GO:0032433 filopodium tip", "go_biological_process": "GO:0030835 negative regulation of actin filament depolymerization;GO:0006417 regulation of translation;GO:0046847 filopodium assembly;GO:0000902 cell morphogenesis;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6UK63-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6XHA5-1", "uniprot_id": [ { "id": "ROC11_DICDI", "url": "https://www.uniprot.org/uniprot/Q6XHA5", "type": "external" } ], "mass": 168497.0, "length": 1487, "protein_name": "Probable serine/threonine-protein kinase roco11", "gene_name": "roco11", 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"2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding", 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Required for optimal cell growth., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q55F36", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006952 defense response;GO:0042127 regulation of cell population proliferation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q70GP4-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q71A39-1", "uniprot_id": [ { "id": "PHLP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q71A39", "type": "external" } ], "mass": 36853.0, "length": 316, "protein_name": "Phosducin-like protein 1", "gene_name": "phlp1", "organism": "Cellular slime mold", "refseq_name": "phosducin-like protein", "refseq_ac": [ { "id": "XP_629439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629439", "type": "external" } ], "gene_names_uniprotkb": "phlp1; DDB_G0292850", "gene_names_refseq": "phlp1", "protein_names_uniprotkb": "Phosducin-like protein 1", "protein_names_refseq": "phosducin-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292850)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14517243;15875012;16135826", "class_list": "", "function": "Required for normal chemotaxis in response to cAMP and folate. Required for the heterodimerization of the G protein beta and gamma subunits gpbA and gpgA, which is itself thought to be necessary for prenylation of the gamma subunit gpgA and its association with plasma membranes., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54CH7", "ec_number_list": [], "go_molecular_function": "GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0006457 protein folding;GO:1902605 heterotrimeric G-protein complex assembly;GO:0008277 regulation of G protein-coupled receptor signaling pathway;GO:0043326 chemotaxis to folate", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q71A39-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75J96-1", "uniprot_id": [ { "id": "RGAP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q75J96", "type": "external" } ], "mass": 118502.0, "length": 1055, "protein_name": "RapA guanosine triphosphatase-activating protein 1", "gene_name": "rapgap1", "organism": "Cellular slime mold", "refseq_name": "RapGAP/RanGAP domain-containing protein", "refseq_ac": [ { "id": "XP_645524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645524", "type": "external" } ], "gene_names_uniprotkb": "rapgap1; DDB_G0271734", "gene_names_refseq": "rapgap1", "protein_names_uniprotkb": "RapA guanosine triphosphatase-activating protein 1", "protein_names_refseq": "RapGAP/RanGAP domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271734); (R-DDI-392517)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;18039932", "class_list": "", "function": "Mediates the deactivation of rap1 and plays an important role in spatially and temporally regulating cell adhesion and chemotaxis by controlling attachment disassembly in the leading edge through the regulation of myosin II assembly and disassembly. Overexpression leads to defective chemotaxis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55AJ8", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0031252 cell leading edge", "go_biological_process": "GO:0051056 regulation of small GTPase mediated signal transduction;GO:0051591 response to cAMP;GO:0031589 cell-substrate adhesion;GO:0007163 establishment or maintenance of cell polarity;GO:0030837 negative regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q75J96-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75JI3-1", "uniprot_id": [ { "id": "NSF_DICDI", "url": "https://www.uniprot.org/uniprot/Q75JI3", "type": "external" } ], "mass": 82233.0, "length": 738, "protein_name": "Vesicle-fusing ATPase", "gene_name": "nsfA", "organism": "Cellular slime mold", "refseq_name": "N-ethylmaleimide-sensitive fusion protein", "refseq_ac": [ { "id": "XP_643273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643273", "type": "external" } ], "gene_names_uniprotkb": "nsfA; DDB_G0276153", "gene_names_refseq": "nsfA", "protein_names_uniprotkb": "Vesicle-fusing ATPase; 3.6.4.6; N-ethylmaleimide-sensitive factor A; NEM-sensitive fusion protein A; Vesicular-fusion protein nfsA", "protein_names_refseq": "N-ethylmaleimide-sensitive fusion protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276153); (R-DDI-204005); (R-DDI-6807878); (R-DDI-6811434); (R-DDI-6811438); (R-DDI-6811440)", "pathway_count": 6, "publication_count": 10, "publication_id_list": "10727946;10978342;12097910;12175335;12183371;15875012;1730725;17606987;9422733;9511743", "class_list": "", "function": "Required for vesicle-mediated transport. Involved in endocytosis and endosome-endosome fusion. May be required for transport from the endoplasmic reticulum to the Golgi stack, and for the fusion of transport vesicles within the Golgi cisternae. Required for cell polarity, locomotion and chemotaxis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15646;Q552E0", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0016020 membrane;GO:0010008 endosome membrane;GO:0005795 Golgi stack", "go_biological_process": "GO:0035494 SNARE complex disassembly;GO:0006897 endocytosis;GO:0006935 chemotaxis;GO:0006909 phagocytosis;GO:0043001 Golgi to plasma membrane protein transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q75JI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75JK0-1", "uniprot_id": [ { "id": "ZAK1_DICDI", "url": "https://www.uniprot.org/uniprot/Q75JK0", "type": "external" } ], "mass": 89690.0, "length": 781, "protein_name": "Dual specificity protein kinase zakA", "gene_name": "zakA", "organism": "Cellular slime mold", "refseq_name": "CZAK family protein kinase", "refseq_ac": [ { "id": "XP_643301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643301", "type": "external" } ], "gene_names_uniprotkb": "zakA; DDB_G0276025; zak1", "gene_names_refseq": "zakA", "protein_names_uniprotkb": "Dual specificity protein kinase zakA; 2.7.12.1; Zaphod K Kinase 1; Zaphod kinase 1; Zaphod kinase A", "protein_names_refseq": "CZAK family protein kinase; NZAK subfamily protein kinase; protein kinase, STE group; protein kinase, TKL group; protein tyrosine kinase; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276025); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 7, "publication_count": 5, "publication_id_list": "10571182;12097910;15875012;17085634;21205787", "class_list": "", "function": "Positive regulator of gsk3/gskA activity required for cell pattern formation and a downstream effector of carC. The kinases, gsk3/gskA, zakA and zak2, form part of a signaling pathway that responds to extracellular cyclic AMP. The pathway has a role in transcriptional regulation; required to direct prespore/spore fates during development. ZakA negatively regulates prestalk differentiation by regulating expression of ecmB. Phosphorylates Y-214 of gsk3/gskA, in vitro., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q552C7;Q9U478", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0097515 asexual spore wall", "go_biological_process": "GO:0001708 cell fate specification;GO:0007165 signal transduction;GO:0033674 positive regulation of kinase activity;GO:0042659 regulation of cell fate specification;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q75JK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75JQ3-1", "uniprot_id": [ { "id": "PEX2_DICDI", "url": "https://www.uniprot.org/uniprot/Q75JQ3", "type": "external" } ], "mass": 48982.0, "length": 423, "protein_name": "Peroxisome biogenesis factor 2", "gene_name": "pex2", "organism": "Cellular slime mold", "refseq_name": "RING zinc finger-containing protein", "refseq_ac": [ { "id": "XP_645304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645304", "type": "external" } ], "gene_names_uniprotkb": "pex2; DDB_G0272234", "gene_names_refseq": "pex2", "protein_names_uniprotkb": "Peroxisome biogenesis factor 2; 2.3.2.36; Peroxin-2", "protein_names_refseq": "RING zinc finger-containing protein; peroxin 2; peroxisomal biogenesis factor 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272234)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling. The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase. PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-11', a modification that acts as a signal for PEX5 extraction into the cytosol., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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DDB_G0277401; dvacB", "gene_names_refseq": "vatB", "protein_names_uniprotkb": "V-type proton ATPase subunit B; V-ATPase subunit B; Vacuolar proton pump subunit B", "protein_names_refseq": "vacuolar H+ ATPase B subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277401); (R-DDI-1222556); (R-DDI-77387); (R-DDI-917977); (R-DDI-9639288); (R-DDI-983712)", "pathway_count": 6, "publication_count": 8, "publication_id_list": "12097910;15875012;16445684;16926386;7593293;8509452;8899714;9426215", "class_list": "", "function": "Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The B subunit is non-catalytic but combines with other subunits to form the catalytic complex. V-ATPase is responsible for energizing electrophoretic K(+)/2H(+) antiport by generating a transmembrane voltage of more than 200 mV (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q23926;Q54ZN4", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0030139 endocytic vesicle;GO:0045335 phagocytic vesicle;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain", "go_biological_process": "GO:0009617 response to bacterium;GO:0046034 ATP metabolic process;GO:0007035 vacuolar acidification;GO:1902600 proton transmembrane transport;GO:0036176 response to neutral pH", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q76NU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q76NV1-1", "uniprot_id": [ { "id": "DYRK1_DICDI", "url": "https://www.uniprot.org/uniprot/Q76NV1", "type": "external" } ], "mass": 97098.0, "length": 836, "protein_name": "Probable serine/threonine-protein kinase dyrk1", "gene_name": "dyrk1", "organism": "Cellular slime mold", "refseq_name": "DYRK family protein kinase", "refseq_ac": [ { "id": "XP_642598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642598", "type": "external" } ], "gene_names_uniprotkb": "dyrk1; DDB_G0277485", "gene_names_refseq": "dyrk1", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase dyrk1; 2.7.12.1; Dual specificity tyrosine-phosphorylation regulated kinase 1", "protein_names_refseq": "DYRK family protein kinase; protein kinase, CMGC group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277485)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54ZP4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q76NV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q76NW2-1", "uniprot_id": [ { "id": "H4_DICDI", "url": "https://www.uniprot.org/uniprot/Q76NW2", "type": "external" } ], "mass": 12017.0, "length": 108, "protein_name": "Histone H4", "gene_name": "H4a; H4b", "organism": "Cellular slime mold", "refseq_name": "histone H4", "refseq_ac": [ { "id": "XP_642712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642712", "type": "external" } ], "gene_names_uniprotkb": "H4a; H4b; DDB_G0276863; DDB_G0277183", "gene_names_refseq": "H4a", "protein_names_uniprotkb": "Histone H4", "protein_names_refseq": "histone H4", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276863); (ddi:DDB_G0277183); (R-DDI-2299718); (R-DDI-2559580); (R-DDI-3214815); (R-DDI-3214847); (R-DDI-3214858); (R-DDI-4551638); (R-DDI-5693565); (R-DDI-68616); (R-DDI-73772); (R-DDI-9909649); (R-DDI-9943411); (R-DDI-9943962)", "pathway_count": 14, "publication_count": 3, "publication_id_list": "12097910;15875012;497154", "class_list": "", "function": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q550A4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0031012 extracellular matrix;GO:0000786 nucleosome", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006334 nucleosome assembly;GO:0046689 response to mercury ion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q76NW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q76P24-1", "uniprot_id": [ { "id": "HD_DICDI", "url": "https://www.uniprot.org/uniprot/Q76P24", "type": "external" } ], "mass": 346847.0, "length": 3095, "protein_name": "HD protein homolog", "gene_name": "htt", "organism": "Cellular slime mold", "refseq_name": "Huntingtin family protein", "refseq_ac": [ { "id": "XP_645159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645159", "type": "external" } ], "gene_names_uniprotkb": "htt; DDB_G0272344; hd", "gene_names_refseq": "hd", "protein_names_uniprotkb": "HD protein homolog", "protein_names_refseq": "Huntingtin family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272344)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "May play a role in microtubule-mediated transport or vesicle function., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q55A25", "ec_number_list": [], "go_molecular_function": "GO:0017020 myosin phosphatase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006935 chemotaxis;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0051592 response to calcium ion;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q76P24-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KWK5-1", "uniprot_id": [ { "id": "PRP19_DICDI", "url": "https://www.uniprot.org/uniprot/Q7KWK5", "type": "external" } ], "mass": 56811.0, "length": 514, "protein_name": "Pre-mRNA-processing factor 19", "gene_name": "prp19", "organism": "Cellular slime mold", "refseq_name": "WD40 repeat-containing protein", "refseq_ac": [ { "id": "XP_642890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642890", "type": "external" } ], "gene_names_uniprotkb": "prp19; DDB_G0276803", "gene_names_refseq": "prp19", "protein_names_uniprotkb": "Pre-mRNA-processing factor 19; 2.3.2.27; PRP19/PSO4 homolog; RING-type E3 ubiquitin transferase PRP19", "protein_names_refseq": "WD40 repeat-containing protein; pre-mRNA processing factor 19", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276803); (R-DDI-6781823); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-72163)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Probable ubiquitin-protein ligase mainly involved in pre-mRNA splicing and DNA repair. Core component of the Prp19 complex/PRP19C/Nineteen complex/NTC which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q550P2", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "GO:0000375 RNA splicing, via transesterification reactions;GO:0006281 DNA repair;GO:0000398 mRNA splicing, via spliceosome;GO:0070534 protein K63-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7KWK5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KWM5-1", "uniprot_id": [ { "id": "ALG2_DICDI", "url": "https://www.uniprot.org/uniprot/Q7KWM5", "type": "external" } ], "mass": 47614.0, "length": 420, "protein_name": "Alpha-1,3/1,6-mannosyltransferase ALG2", "gene_name": "alg2", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644980", "type": "external" } ], "gene_names_uniprotkb": "alg2; DDB_G0272730", "gene_names_refseq": "alg2", "protein_names_uniprotkb": "Alpha-1,3/1,6-mannosyltransferase ALG2; 2.4.1.132; 2.4.1.257; Asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272730); (R-DDI-446193)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "glycogene;glycosyltransferase", "function": "Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q558T6", "ec_number_list": [ { "id": "2.4.1.132", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.132", "type": "external" }, { "id": "2.4.1.257", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.257", "type": "external" } ], "go_molecular_function": "GO:0000033 alpha-1,3-mannosyltransferase activity;GO:0004378 GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity;GO:0102704 GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7KWM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7KWS2-1", "uniprot_id": [ { "id": "EXPL3_DICDI", "url": "https://www.uniprot.org/uniprot/Q7KWS2", "type": "external" } ], "mass": 37104.0, "length": 335, "protein_name": "Expansin-like protein 3", "gene_name": "expl3", "organism": "Cellular slime mold", "refseq_name": "expansin-like protein", "refseq_ac": [ { "id": "XP_643217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643217", "type": "external" } ], "gene_names_uniprotkb": "expl3; DDB_G0276287", "gene_names_refseq": "expl3", "protein_names_uniprotkb": "Expansin-like protein 3; Ddexpl3", "protein_names_refseq": "expansin-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276287)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11891242;12097910;12832080;15470253;15875012;17481898;17878305", "class_list": "", "function": "May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q551W0", "ec_number_list": [], "go_molecular_function": "GO:0030248 cellulose binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0031153 slug development involved in sorocarp development;GO:0036360 sorocarp stalk morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q7KWS2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7M438-1", "uniprot_id": [ { "id": "RNDI_DICDI", "url": "https://www.uniprot.org/uniprot/Q7M438", "type": "external" } ], "mass": 24584.0, "length": 223, "protein_name": "Ribonuclease DdI", "gene_name": "ddiA", "organism": "Cellular slime mold", "refseq_name": "ribonuclease T2", "refseq_ac": [ { "id": "XP_640939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640939", "type": "external" } ], "gene_names_uniprotkb": "ddiA; DDB_G0281293; ddi", "gene_names_refseq": "ddiA", "protein_names_uniprotkb": "Ribonuclease DdI; 4.6.1.19; RNase DdI", "protein_names_refseq": "ribonuclease T2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281293)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10052134;15875012;9756633", "class_list": "", "function": "Releases mononucleotides from RNA in the order of 3'-GMP > 3'-UMP > 3'-AMP > 3'-CMP., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54U37", "ec_number_list": [ { "id": "4.6.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.19", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0004521 RNA endonuclease activity;GO:0033897 ribonuclease T2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7M438-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YSJ4-1", "uniprot_id": [ { "id": "PSIF_DICDI", "url": "https://www.uniprot.org/uniprot/Q7YSJ4", "type": "external" } ], "mass": 76482.0, "length": 708, "protein_name": "Protein psiF", "gene_name": "psiF", "organism": "Cellular slime mold", "refseq_name": "PA14 domain-containing protein", "refseq_ac": [ { "id": "XP_642054", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642054", "type": "external" } ], "gene_names_uniprotkb": "psiF; DDB_G0278581; dicA1; dicA", "gene_names_refseq": "psiF", "protein_names_uniprotkb": "Protein psiF; Discoidin-inducing complex subunit A", "protein_names_refseq": "PA14 domain-containing protein; discoidin-inducing complex protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278581)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;15947191", "class_list": "", "function": "Acts as a quorum sensing protein regulating discoidin gene expression during growth and development. D.discoideum is a single-celled amoebae and switches to multicellular development when food becomes limited. As the growing cells reach a high density, they begin expressing discoidin genes. The ability of psiF/dicA to induce discoidin gene expression when present in conditioned medium, suggests that it allows cells to sense their local density., [UniProtKB, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q54YZ8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0009372 quorum sensing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7YSJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YSW8-1", "uniprot_id": [ { "id": "PP2BA_DICDI", "url": "https://www.uniprot.org/uniprot/Q7YSW8", "type": "external" } ], "mass": 71393.0, "length": 623, "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit", "gene_name": "canA", "organism": "Cellular slime mold", "refseq_name": "CaM-dependent protein phosphatase, catalytic subunit", "refseq_ac": [ { "id": "XP_642811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642811", "type": "external" } ], "gene_names_uniprotkb": "canA; DDB_G0276883", "gene_names_refseq": "canA", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2B catalytic subunit; 3.1.3.16; Calcineurin subunit A", "protein_names_refseq": "CaM-dependent protein phosphatase, catalytic subunit; calcineurin A; protein phosphatase-2B; protein serine/threonine phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276883)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10608845;11352578;12097910;15875012;8681950;9765812", "class_list": "", "function": "Catalytic subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q27558;Q27560;Q550X1", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0033192 calmodulin-dependent protein phosphatase activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005955 calcineurin complex", "go_biological_process": "GO:0097720 calcineurin-mediated signaling;GO:0043157 response to cation stress;GO:0031149 sorocarp stalk cell differentiation;GO:0031156 regulation of sorocarp development;GO:0044671 sorocarp spore cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q7YSW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YXD4-1", "uniprot_id": [ { "id": "P80_DICDI", "url": "https://www.uniprot.org/uniprot/Q7YXD4", "type": "external" } ], "mass": 57633.0, "length": 530, "protein_name": "Protein P80", "gene_name": "p80", "organism": "Cellular slime mold", "refseq_name": "endosomal membrane protein", "refseq_ac": [ { "id": "XP_637238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637238", "type": "external" } ], "gene_names_uniprotkb": "p80; DDB_G0287297", "gene_names_refseq": "p80", "protein_names_uniprotkb": "Protein P80; Endosomal membrane protein", "protein_names_refseq": "endosomal membrane protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287297)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11831389;15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54KI5", "ec_number_list": [], "go_molecular_function": "GO:0044325 transmembrane transporter binding;GO:0005375 copper ion transmembrane transporter activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030666 endocytic vesicle membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0035434 copper ion transmembrane transport;GO:0006909 phagocytosis;GO:0009617 response to bacterium;GO:0015677 copper ion import", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7YXD4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YXU4-1", "uniprot_id": [ { "id": "CPNA_DICDI", "url": "https://www.uniprot.org/uniprot/Q7YXU4", "type": "external" } ], "mass": 65878.0, "length": 600, "protein_name": "Copine-A", "gene_name": "cpnA", "organism": "Cellular slime mold", "refseq_name": "copine A", "refseq_ac": [ { "id": "XP_629291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629291", "type": "external" } ], "gene_names_uniprotkb": "cpnA; DDB_G0293008", "gene_names_refseq": "cpnA", "protein_names_uniprotkb": "Copine-A", "protein_names_refseq": "copine A; phospholipid-binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293008); (R-DDI-1483206); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15875012;16343335;17259548", "class_list": "", "function": "Required for cytokinesis, contractile vacuole function and development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54CC8", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0051592 response to calcium ion;GO:0071277 cellular response to calcium ion;GO:0000281 mitotic cytokinesis;GO:0055074 calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7YXU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7Z203-1", "uniprot_id": [ { "id": "CUPB_DICDI", "url": "https://www.uniprot.org/uniprot/Q7Z203", "type": "external" } ], "mass": 85657.0, "length": 769, "protein_name": "Calcium up-regulated protein B", "gene_name": "cupB", "organism": "Cellular slime mold", "refseq_name": "calcium up-regulated protein", "refseq_ac": [ { "id": "XP_636022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636022", "type": "external" } ], "gene_names_uniprotkb": "cupB; DDB_G0289815", "gene_names_refseq": "cupB", "protein_names_uniprotkb": "Calcium up-regulated protein B", "protein_names_refseq": "calcium up-regulated protein; ricin B lectin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289815)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14871937;15875012", "class_list": "", "function": "May play an important role in stabilizing and/or regulating the cell membrane during Ca(2+) stress or certain stages of development., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54GY5", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0043157 response to cation stress;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7Z203-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7Z2B8-1", "uniprot_id": [ { "id": "MLCD_DICDI", "url": "https://www.uniprot.org/uniprot/Q7Z2B8", "type": "external" } ], "mass": 16519.0, "length": 147, "protein_name": "Myosin-ID light chain", "gene_name": "mlcD", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_642258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642258", "type": "external" } ], "gene_names_uniprotkb": "mlcD; DDB_G0277917", "gene_names_refseq": "mlcD", "protein_names_uniprotkb": "Myosin-ID light chain; Calmodulin-like protein mlcD; MlcD; Myosin light chain mlcD", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277917); (R-DDI-6798695)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12826013;15875012;16415352", "class_list": "", "function": "Functions as the light chain for myosin-D. Has low affinity for calcium., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54YE4", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0032036 myosin heavy chain binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016459 myosin complex;GO:0062201 actin wave;GO:0070687 macropinocytic cup cytoskeleton", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7Z2B8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869E1-1", "uniprot_id": [ { "id": "DNLI1_DICDI", "url": "https://www.uniprot.org/uniprot/Q869E1", "type": "external" } ], "mass": 137514.0, "length": 1192, "protein_name": "DNA ligase 1", "gene_name": "lig1", "organism": "Cellular slime mold", "refseq_name": "DNA ligase I", "refseq_ac": [ { "id": "XP_644124", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644124", "type": "external" } ], "gene_names_uniprotkb": "lig1; DDB_G0274493", "gene_names_refseq": "lig1", "protein_names_uniprotkb": "DNA ligase 1; 6.5.1.1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1", "protein_names_refseq": "DNA ligase I", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274493); (R-DDI-110362); (R-DDI-5358565); (R-DDI-5358606); (R-DDI-5685938); (R-DDI-69183)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q556E8", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006273 lagging strand elongation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q869E1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869N2-1", "uniprot_id": [ { "id": "PAKB_DICDI", "url": "https://www.uniprot.org/uniprot/Q869N2", "type": "external" } ], "mass": 93123.0, "length": 852, "protein_name": "Serine/threonine-protein kinase pakB", "gene_name": "pakB", "organism": "Cellular slime mold", "refseq_name": "PAKA subfamily protein kinase", "refseq_ac": [ { "id": "XP_643105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643105", "type": "external" } ], "gene_names_uniprotkb": "pakB; DDB_G0276459; Ddpak; mihck", "gene_names_refseq": "pakB", "protein_names_uniprotkb": "Serine/threonine-protein kinase pakB; 2.7.11.1; Myosin I heavy chain kinase; dPAKb", "protein_names_refseq": "PAKA subfamily protein kinase; STE20 family protein kinase; myosin I heavy chain kinase; myosin heavy chain kinase; p21-activated protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276459); (R-DDI-2029482); (R-DDI-389359); (R-DDI-3928662); (R-DDI-445144); (R-DDI-5621575); (R-DDI-5627123); (R-DDI-5687128); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 11, "publication_count": 5, "publication_id_list": "12097910;15509655;15875012;8900194;9774403", "class_list": "", "function": "Regulator of the myosin I component of the cytoskeleton: required for regulation of cytokinesis, phagocytosis and pinocytosis., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "O00911;Q551M5;Q94488", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0005543 phospholipid binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006909 phagocytosis;GO:0050766 positive regulation of phagocytosis;GO:0000281 mitotic cytokinesis;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q869N2-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869Q3-1", "uniprot_id": [ { "id": "NAPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q869Q3", "type": "external" } ], "mass": 133540.0, "length": 1160, "protein_name": "Nck-associated protein 1 homolog", "gene_name": "napA", "organism": "Cellular slime mold", "refseq_name": "component of SCAR regulatory complex", "refseq_ac": [ { "id": "XP_644083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644083", "type": "external" } ], "gene_names_uniprotkb": "napA; DDB_G0274519; nap1", "gene_names_refseq": "napA", "protein_names_uniprotkb": "Nck-associated protein 1 homolog", "protein_names_refseq": "component of SCAR regulatory complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274519); (R-DDI-2029482); (R-DDI-5663213); (R-DDI-6798695); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 7, "publication_count": 3, "publication_id_list": "12097910;15875012;16581519", "class_list": "", "function": "Involved in regulation of actin and microtubule organization. Involved in cell adhesion., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q555I6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0031252 cell leading edge;GO:0031209 SCAR complex;GO:0031143 pseudopodium;GO:0032433 filopodium tip", "go_biological_process": "GO:0008064 regulation of actin polymerization or depolymerization;GO:0016477 cell migration;GO:0046847 filopodium assembly;GO:0000902 cell morphogenesis;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q869Q3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869S5-1", "uniprot_id": [ { "id": "DOKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q869S5", "type": "external" } ], "mass": 186136.0, "length": 1671, "protein_name": "Hybrid signal transduction protein dokA", "gene_name": "dokA", "organism": "Cellular slime mold", "refseq_name": "histidine kinase", "refseq_ac": [ { "id": "XP_644179", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644179", "type": "external" } ], "gene_names_uniprotkb": "dokA; DDB_G0274101", "gene_names_refseq": "dokA", "protein_names_uniprotkb": "Hybrid signal transduction protein dokA", "protein_names_refseq": "histidine kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274101)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11060029;11299049;12097910;15875012;8670893", "class_list": "", "function": "Part of the osmoregulatory pathway which leads to the increase of intracellular cAMP concentration in response to hyperosmotic stress. Thought to negatively regulate the rdeA-regA pathway by acting as a phosphatase towards the HPt protein rdeA. Has probably no histidine kinase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q23901;Q554Z4", "ec_number_list": [], "go_molecular_function": "GO:0000155 phosphorelay sensor kinase activity;GO:0000156 phosphorelay response regulator activity;GO:0009927 histidine phosphotransfer kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0048870 cell motility;GO:0000160 phosphorelay signal transduction system;GO:0007234 osmosensory signaling via phosphorelay pathway;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q869S5-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869S7-1", "uniprot_id": [ { "id": "SUCB2_DICDI", "url": "https://www.uniprot.org/uniprot/Q869S7", "type": "external" } ], "mass": 45664.0, "length": 420, "protein_name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "gene_name": "scsB", "organism": "Cellular slime mold", "refseq_name": "GTP-specific succinyl-CoA synthetase beta subunit", "refseq_ac": [ { "id": "XP_644183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644183", "type": "external" } ], "gene_names_uniprotkb": "scsB; DDB_G0274449; suclg2", "gene_names_refseq": "scsB", "protein_names_uniprotkb": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; 6.2.1.4; G-SCS; GTP-specific succinyl-CoA synthetase subunit beta; GTPSCS; SCS-betaG; Succinyl-CoA synthetase beta-G chain", "protein_names_refseq": "GTP-specific succinyl-CoA synthetase beta subunit; succinate-CoA ligase; succinyl-CoA synthetase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274449); (R-DDI-71403)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554Z0", "ec_number_list": [ { "id": "6.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.4", "type": "external" }, { "id": "6.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.5", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004776 succinate-CoA ligase (GDP-forming) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042709 succinate-CoA ligase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q869S7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869V1-1", "uniprot_id": [ { "id": "NRAM1_DICDI", "url": "https://www.uniprot.org/uniprot/Q869V1", "type": "external" } ], "mass": 60034.0, "length": 533, "protein_name": "Metal transporter nramp1 homolog", "gene_name": "nramp1", "organism": "Cellular slime mold", "refseq_name": "natural resistance-associated macrophage protein", "refseq_ac": [ { "id": "XP_642974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642974", "type": "external" } ], "gene_names_uniprotkb": "nramp1; DDB_G0276973; nramp; slc11a1", "gene_names_refseq": "nramp1", "protein_names_uniprotkb": "Metal transporter nramp1 homolog; Natural resistance-associated membrane protein 1", "protein_names_refseq": "natural resistance-associated macrophage protein; solute carrier family 11 member 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276973); (R-DDI-1222556); (R-DDI-425410); (R-DDI-6798695); (R-DDI-6803544); (R-DDI-917937)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "12097910;15875012;16445684;22992462;26208637;28680861", "class_list": "", "function": "Depletes iron from the phagolysosome in an ATP-dependent process (PubMed:16445684). Required for iron efflux from macropinosomes (PubMed:26208637). May rather act as a symporter of protons and metal cations in an ATP-dependent process (PubMed:16445684). Can transport Fe(2+) and Mn(2+), but not Fe(3+) or Cu(2+); transport is electrogenic and proton dependent (PubMed:26208637). Required for resistance to pathogenic bacteria, such as Legionella pneumophila and Francisella noatunensis subsp. noatunensis (PubMed:16445684, PubMed:22992462, PubMed:28680861)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q550F8", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005384 manganese ion transmembrane transporter activity;GO:0015093 ferrous iron transmembrane transporter activity;GO:0005381 iron ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030670 phagocytic vesicle membrane;GO:0032010 phagolysosome;GO:0010008 endosome membrane", "go_biological_process": "GO:0034755 iron ion transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0006909 phagocytosis;GO:0009617 response to bacterium;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q869V1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869W6-1", "uniprot_id": [ { "id": "MYLKG_DICDI", "url": "https://www.uniprot.org/uniprot/Q869W6", "type": "external" } ], "mass": 38967.0, "length": 349, "protein_name": "Probable myosin light chain kinase DDB_G0275057", "gene_name": "DDB_G0275057", "organism": "Cellular slime mold", "refseq_name": "CAMK1 family protein kinase", "refseq_ac": [ { "id": "XP_643776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643776", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0275057", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable myosin light chain kinase DDB_G0275057; 2.7.11.18", "protein_names_refseq": "CAMK1 family protein kinase; protein kinase, CAMK group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275057)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "May phosphorylate a specific serine in the N-terminus of a myosin light chain., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554D5", "ec_number_list": [ { "id": "2.7.11.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.18", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004687 myosin light chain kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q869W6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869Y7-1", "uniprot_id": [ { "id": "ODO2_DICDI", "url": "https://www.uniprot.org/uniprot/Q869Y7", "type": "external" } ], "mass": 47633.0, "length": 439, "protein_name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "gene_name": "odhB", "organism": "Cellular slime mold", "refseq_name": "2-oxoglutarate dehydrogenase E2 component", "refseq_ac": [ { "id": "XP_643853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643853", "type": "external" } ], "gene_names_uniprotkb": "odhB; DDB_G0275029; dlst", "gene_names_refseq": "odhB", "protein_names_uniprotkb": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; 2-oxoglutarate dehydrogenase complex component E2; 2.3.1.61; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; OGDC-E2", "protein_names_refseq": "2-oxoglutarate dehydrogenase E2 component; dihydrolipoamide S-succinyltransferase; dihydrolipoyllysine-residue succinyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275029); (R-DDI-6783984); (R-DDI-9853506); (R-DDI-9857492); (R-DDI-9858328)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "12097910;15875012;16512674", "class_list": "", "function": "The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q553V8", "ec_number_list": [ { "id": "1.8.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.4", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "6.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.1.20", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "1.2.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.-", "type": "external" }, { "id": "2.3.1.61", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.61", "type": "external" } ], "go_molecular_function": "GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0045252 oxoglutarate dehydrogenase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q869Y7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q869Z4-1", "uniprot_id": [ { "id": "PCKGM_DICDI", "url": "https://www.uniprot.org/uniprot/Q869Z4", "type": "external" } ], "mass": 72462.0, "length": 653, "protein_name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "gene_name": "pck2", "organism": "Cellular slime mold", "refseq_name": "phosphoenolpyruvate carboxykinase", "refseq_ac": [ { "id": "XP_645396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645396", "type": "external" } ], "gene_names_uniprotkb": "pck2; DDB_G0271904", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; 4.1.1.32; PEPCK-M", "protein_names_refseq": "phosphoenolpyruvate carboxykinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271904); (R-DDI-70263)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55AF8", "ec_number_list": [ { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0030145 manganese ion binding;GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0046327 glycerol biosynthetic process from pyruvate;GO:0042594 response to starvation;GO:0071333 cellular response to glucose stimulus;GO:0006094 gluconeogenesis;GO:0006107 oxaloacetate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q869Z4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86A17-1", "uniprot_id": [ { "id": "DHPR_DICDI", "url": "https://www.uniprot.org/uniprot/Q86A17", "type": "external" } ], "mass": 24651.0, "length": 231, "protein_name": "Dihydropteridine reductase", "gene_name": "qdpr", "organism": "Cellular slime mold", "refseq_name": "dihydropteridine reductase", "refseq_ac": [ { "id": "XP_644903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644903", "type": "external" } ], "gene_names_uniprotkb": "qdpr; DDB_G0272684", "gene_names_refseq": "qdpr", "protein_names_uniprotkb": "Dihydropteridine reductase; 1.5.1.34; Quinoid dihydropteridine reductase", "protein_names_refseq": "dihydropteridine reductase; quinoid dihydropteridine reductase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272684); (R-DDI-8964208)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;18997329", "class_list": "", "function": "The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q559B3", "ec_number_list": [ { "id": "1.5.1.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.34", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0051287 NAD binding;GO:0070402 NADPH binding;GO:0004155 6,7-dihydropteridine reductase activity;GO:0070404 NADH binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0006559 L-phenylalanine catabolic process;GO:0006729 tetrahydrobiopterin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86A17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86A84-1", "uniprot_id": [ { "id": "MPPA1_DICDI", "url": "https://www.uniprot.org/uniprot/Q86A84", "type": "external" } ], "mass": 73262.0, "length": 654, "protein_name": "Mitochondrial-processing peptidase subunit alpha-1", "gene_name": "mppA1", "organism": "Cellular slime mold", "refseq_name": "mitochondrial processing peptidase alpha subunit", "refseq_ac": [ { "id": "XP_001134603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001134603", "type": "external" } ], "gene_names_uniprotkb": "mppA1; DDB_G0274809; mppA", "gene_names_refseq": "mppA", "protein_names_uniprotkb": "Mitochondrial-processing peptidase subunit alpha-1; Alpha-MPP; Ddalpha-MPP; Inactive zinc metalloprotease alpha-1", "protein_names_refseq": "mitochondrial processing peptidase alpha subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274809); (R-DDI-611105); (R-DDI-9837999)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12097910;15875012;18603769", "class_list": "", "function": "Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1ZXL4;Q3LG19", "ec_number_list": [], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0017087 mitochondrial processing peptidase complex", "go_biological_process": "GO:0006627 protein processing involved in protein targeting to mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86A84-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86AC8-1", "uniprot_id": [ { "id": "MYOG_DICDI", "url": "https://www.uniprot.org/uniprot/Q86AC8", "type": "external" } ], "mass": 386918.0, "length": 3446, "protein_name": "Myosin-G heavy chain", "gene_name": "myoG", "organism": "Cellular slime mold", "refseq_name": "unconventional myosin heavy chain", "refseq_ac": [ { "id": "XP_643200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643200", "type": "external" } ], "gene_names_uniprotkb": "myoG; DDB_G0276363", "gene_names_refseq": "myoG", "protein_names_uniprotkb": "Myosin-G heavy chain", "protein_names_refseq": "unconventional myosin heavy chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276363)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;16857047", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q551R1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0005902 microvillus;GO:0016459 myosin complex", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030041 actin filament polymerization;GO:0072657 protein localization to membrane;GO:0030010 establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86AC8-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86AE1-1", "uniprot_id": [ { "id": "Y9853_DICDI", "url": "https://www.uniprot.org/uniprot/Q86AE1", "type": "external" } ], "mass": 58906.0, "length": 527, "protein_name": "Probable serine/threonine-protein kinase DDB_G0271538", "gene_name": "DDB_G0271538", "organism": "Cellular slime mold", "refseq_name": "LISK family protein kinase", "refseq_ac": [ { "id": "XP_645575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645575", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0271538", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase DDB_G0271538; 2.7.11.1", "protein_names_refseq": "LISK family protein kinase; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271538)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;12796308;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55AX1", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0010506 regulation of autophagy;GO:0042594 response to starvation;GO:0000423 mitophagy;GO:0034727 piecemeal microautophagy of the nucleus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86AE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86AQ7-1", "uniprot_id": [ { "id": "VAM7B_DICDI", "url": "https://www.uniprot.org/uniprot/Q86AQ7", "type": "external" } ], "mass": 29561.0, "length": 260, "protein_name": "Vesicle-associated membrane protein 7B", "gene_name": "vamp7B", "organism": "Cellular slime mold", "refseq_name": "longin domain-containing protein", "refseq_ac": [ { "id": "XP_642704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642704", "type": "external" } ], "gene_names_uniprotkb": "vamp7B; DDB_G0277173", "gene_names_refseq": "vamp7B", "protein_names_uniprotkb": "Vesicle-associated membrane protein 7B", "protein_names_refseq": "longin domain-containing protein; synaptobrevin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277173); (R-DDI-199992)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q550B2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030658 transport vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0008333 endosome to lysosome transport;GO:0006906 vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86AQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86AS5-1", "uniprot_id": [ { "id": "PPCE_DICDI", "url": "https://www.uniprot.org/uniprot/Q86AS5", "type": "external" } ], "mass": 87555.0, "length": 760, "protein_name": "Prolyl endopeptidase", "gene_name": "prep", "organism": "Cellular slime mold", "refseq_name": "prolyl oligopeptidase", "refseq_ac": [ { "id": "XP_644295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644295", "type": "external" } ], "gene_names_uniprotkb": "prep; DDB_G0274387; dpoA", "gene_names_refseq": "dpoA", "protein_names_uniprotkb": "Prolyl endopeptidase; 3.4.21.26; PE; POase; Post-proline cleaving enzyme", "protein_names_refseq": "prolyl oligopeptidase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274387)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10329620;12097910;15875012", "class_list": "", "function": "Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554M8;Q9XZR9", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0070012 oligopeptidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0010226 response to lithium ion;GO:0009966 regulation of signal transduction;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86AS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86AT8-1", "uniprot_id": [ { "id": "SPKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q86AT8", "type": "external" } ], "mass": 72983.0, "length": 638, "protein_name": "Stress-activated protein kinase alpha", "gene_name": "spkA-1; spkA-2", "organism": "Cellular slime mold", "refseq_name": "ARK family protein kinase", "refseq_ac": [ { "id": "XP_644604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644604", "type": "external" } ], "gene_names_uniprotkb": "spkA-1; spkA-2; DDB_G0273445; DDB_G0273531", "gene_names_refseq": "spkA-1", "protein_names_uniprotkb": "Stress-activated protein kinase alpha; 2.7.11.1; SAPK-alpha", "protein_names_refseq": "ARK family protein kinase; SAM domain-containing protein; ankyrin repeat-containing protein; protein kinase, TKL group; stress-activated MEK-like kinase; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273445); (ddi:DDB_G0273531); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "12097910;14593072;15875012;17878305", "class_list": "", "function": "May be involved in cortical F-actin organization and resistance to osmotic stress. Activated upon cell detachment, in vitro., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q23859;Q557I8", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0003779 actin binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0006935 chemotaxis;GO:0006970 response to osmotic stress;GO:0007165 signal transduction;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q86AT8-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86B14-1", "uniprot_id": [ { "id": "MCM6_DICDI", "url": "https://www.uniprot.org/uniprot/Q86B14", "type": "external" } ], "mass": 97772.0, "length": 867, "protein_name": "DNA replication licensing factor mcm6", "gene_name": "mcm6", "organism": "Cellular slime mold", "refseq_name": "MCM family protein", "refseq_ac": [ { "id": "XP_001134626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001134626", "type": "external" } ], "gene_names_uniprotkb": "mcm6; DDB_G0272760", "gene_names_refseq": "mcm6", "protein_names_uniprotkb": "DNA replication licensing factor mcm6; 3.6.4.12", "protein_names_refseq": "MCM family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272760); (R-DDI-68867); (R-DDI-68949); (R-DDI-68962); (R-DDI-69052)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1ZXM5", "ec_number_list": [ { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042555 MCM complex", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication;GO:1902969 mitotic DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86B14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86C65-1", "uniprot_id": [ { "id": "TOR_DICDI", "url": "https://www.uniprot.org/uniprot/Q86C65", "type": "external" } ], "mass": 268750.0, "length": 2380, "protein_name": "Serine/threonine-protein kinase tor", "gene_name": "tor", "organism": "Cellular slime mold", "refseq_name": "FRAP subfamily protein kinase", "refseq_ac": [ { "id": "XP_640629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640629", "type": "external" } ], "gene_names_uniprotkb": "tor; DDB_G0281569", "gene_names_refseq": "tor", "protein_names_uniprotkb": "Serine/threonine-protein kinase tor; 2.7.11.1; Target of rapamycin", "protein_names_refseq": "FRAP subfamily protein kinase; PIKK family protein kinase; phosphatidylinositol 3-kinase-related protein kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281569); (R-DDI-1257604); (R-DDI-1632852); (R-DDI-165159); (R-DDI-166208); (R-DDI-3371571); (R-DDI-380972); (R-DDI-389357); (R-DDI-5218920); (R-DDI-5628897); (R-DDI-6804757); (R-DDI-8943724); (R-DDI-9639288); (R-DDI-9856530)", "pathway_count": 14, "publication_count": 6, "publication_id_list": "12626495;15875012;16079174;18635356;18657484;18812082", "class_list": "", "function": "Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein kinase activity, as it appears to phosphorylate pkgB., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54TG2", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0044877 protein-containing complex binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031932 TORC2 complex", "go_biological_process": "GO:0006935 chemotaxis;GO:0031000 response to caffeine;GO:0038202 TORC1 signaling;GO:0016242 negative regulation of macroautophagy;GO:1903664 regulation of asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q86C65-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86CR6-1", "uniprot_id": [ { "id": "ATG12_DICDI", "url": "https://www.uniprot.org/uniprot/Q86CR6", "type": "external" } ], "mass": 14194.0, "length": 124, "protein_name": "Ubiquitin-like protein atg12", "gene_name": "atg12", "organism": "Cellular slime mold", "refseq_name": "autophagy protein 12", "refseq_ac": [ { "id": "XP_639316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639316", "type": "external" } ], "gene_names_uniprotkb": "atg12; DDB_G0282929; apg12", "gene_names_refseq": "atg12", "protein_names_uniprotkb": "Ubiquitin-like protein atg12; APG12-like; Autophagy-related protein 12", "protein_names_refseq": "autophagy protein 12", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282929); (R-DDI-1632852)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12626495;15875012", "class_list": "", "function": "Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54RN5", "ec_number_list": [], "go_molecular_function": "GO:0031386 protein tag activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0034045 phagophore assembly site membrane;GO:0034274 Atg12-Atg5-Atg16 complex", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0006909 phagocytosis;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86CR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86CR8-1", "uniprot_id": [ { "id": "ATG8_DICDI", "url": "https://www.uniprot.org/uniprot/Q86CR8", "type": "external" } ], "mass": 14097.0, "length": 122, "protein_name": "Autophagy-related protein 8", "gene_name": "atg8", "organism": "Cellular slime mold", "refseq_name": "autophagy protein 8", "refseq_ac": [ { "id": "XP_637841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637841", "type": "external" } ], "gene_names_uniprotkb": "atg8; DDB_G0286191; apg8", "gene_names_refseq": "atg8", "protein_names_uniprotkb": "Autophagy-related protein 8; Autophagy-related ubiquitin-like modifier atg8", "protein_names_refseq": "autophagy protein 8", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286191); (R-DDI-1632852); (R-DDI-8854214); (R-DDI-9664873); (R-DDI-9755511)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "12626495;14736886;15875012;16469056", "class_list": "", "function": "Ubiquitin-like modifier involved in autophagosome formation. Participates in membrane fusion events that take place in the secretory pathway (By similarity)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54LZ0", "ec_number_list": [], "go_molecular_function": "GO:0008429 phosphatidylethanolamine binding", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005737 cytoplasm;GO:0031410 cytoplasmic vesicle;GO:0005776 autophagosome;GO:0140220 pathogen-containing vacuole", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0050830 defense response to Gram-positive bacterium;GO:0016236 macroautophagy", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q86CR8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86CR9-1", "uniprot_id": [ { "id": "ATG7_DICDI", "url": "https://www.uniprot.org/uniprot/Q86CR9", "type": "external" } ], "mass": 79859.0, "length": 707, "protein_name": "Ubiquitin-like modifier-activating enzyme atg7", "gene_name": "atg7", "organism": "Cellular slime mold", "refseq_name": "E1-like enzyme family protein", "refseq_ac": [ { "id": "XP_645809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645809", "type": "external" } ], "gene_names_uniprotkb": "atg7; DDB_G0271096; apg7", "gene_names_refseq": "atg7", "protein_names_uniprotkb": "Ubiquitin-like modifier-activating enzyme atg7; ATG12-activating enzyme E1 atg7; Autophagy-related protein 7", "protein_names_refseq": "E1-like enzyme family protein; autophagy protein 7", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271096); (R-DDI-1632852); (R-DDI-6798695); (R-DDI-983168)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "12097910;12626495;15875012;19667176", "class_list": "", "function": "E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy (PubMed:12626495). Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium (PubMed:19667176)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55BK5", "ec_number_list": [], "go_molecular_function": "GO:0019787 ubiquitin-like protein transferase activity;GO:0019778 Atg12 activating enzyme activity;GO:0019779 Atg8 activating enzyme activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000407 phagophore assembly site", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0016236 macroautophagy;GO:0042742 defense response to bacterium;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q86CR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86CS2-1", "uniprot_id": [ { "id": "ATG1_DICDI", "url": "https://www.uniprot.org/uniprot/Q86CS2", "type": "external" } ], "mass": 77175.0, "length": 668, "protein_name": "Serine/threonine-protein kinase atg1", "gene_name": "atg1", "organism": "Cellular slime mold", "refseq_name": "ULK family protein kinase", "refseq_ac": [ { "id": "XP_629641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629641", "type": "external" } ], "gene_names_uniprotkb": "atg1; DDB_G0292390; apg1", "gene_names_refseq": "atg1", "protein_names_uniprotkb": "Serine/threonine-protein kinase atg1; 2.7.11.1; Autophagy-related protein 1", "protein_names_refseq": "ULK family protein kinase; autophagy protein 1; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292390); (R-DDI-1632852); (R-DDI-8854214); (R-DDI-8876198); (R-DDI-8934903)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "12626495;15358773;15875012;16810325;17557329;19667176", "class_list": "", "function": "Serine/threonine protein kinase involved in autophagy (PubMed:12626495, PubMed:17557329). Involved in the control of autophagic vacuolar cell death (PubMed:15358773, PubMed:16810325). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium (PubMed:19667176)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54D55", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008047 enzyme activator activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site", "go_biological_process": "GO:0043457 regulation of cellular respiration;GO:0000045 autophagosome assembly;GO:0001878 response to yeast;GO:0010506 regulation of autophagy;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q86CS2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86CZ2-1", "uniprot_id": [ { "id": "DHKK_DICDI", "url": "https://www.uniprot.org/uniprot/Q86CZ2", "type": "external" } ], "mass": 137716.0, "length": 1213, "protein_name": "Hybrid signal transduction histidine kinase K", "gene_name": "dhkK", "organism": "Cellular slime mold", "refseq_name": "HisK family protein kinase", "refseq_ac": [ { "id": "XP_642392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642392", "type": "external" } ], "gene_names_uniprotkb": "dhkK; DDB_G0277887; smbA", "gene_names_refseq": "dhkK", "protein_names_uniprotkb": "Hybrid signal transduction histidine kinase K; 2.7.13.3; Protein sombrero", "protein_names_refseq": "HisK family protein kinase; histidine kinase; protein kinase, Atypical group; response regulator receiver domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277887)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15875012;16473345;16765443", "class_list": "", "function": "Involved in a signal transduction pathway that regulates morphogenesis and controls entry into the culmination stage. May act via the regA pathway, being activated by a morphogenesis-stimulated ligand, reducing phosphodiesterase regA levels and allowing cAMP level to rise to promote the culmination stage. This protein probably undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54Y10;Q95PH2", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000155 phosphorelay sensor kinase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0031965 nuclear membrane", "go_biological_process": "GO:0031154 culmination involved in sorocarp development;GO:0140582 adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86CZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86D86-1", "uniprot_id": [ { "id": "Q86D86_DICDI", "url": "https://www.uniprot.org/uniprot/Q86D86", "type": "external" } ], "mass": 92861.0, "length": 828, "protein_name": "G-protein-coupled receptor family protein", "gene_name": "rpkA", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor family protein", "refseq_ac": [ { "id": "XP_638982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638982", "type": "external" } ], "gene_names_uniprotkb": "rpkA; DDB_G0283615", "gene_names_refseq": "rpkA", "protein_names_uniprotkb": "G-protein-coupled receptor family protein", "protein_names_refseq": "G-protein-coupled receptor family protein; phosphatidylinositol-4-phosphate 5-kinase; serpentine receptor PIP5K family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283615); (R-DDI-1660499); (R-DDI-6811555); (R-DDI-6811558); (R-DDI-8847453); (R-DDI-8856828)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54QP1", "ec_number_list": [], "go_molecular_function": "GO:0010314 phosphatidylinositol-5-phosphate binding;GO:0004930 G protein-coupled receptor activity;GO:0005524 ATP binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0050766 positive regulation of phagocytosis;GO:0046488 phosphatidylinositol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q86D86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86G47-1", "uniprot_id": [ { "id": "GEFQ_DICDI", "url": "https://www.uniprot.org/uniprot/Q86G47", "type": "external" } ], "mass": 143833.0, "length": 1298, "protein_name": "Ras guanine nucleotide exchange factor Q", "gene_name": "gefQ", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor Q", "refseq_ac": [ { "id": "XP_636051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636051", "type": "external" } ], "gene_names_uniprotkb": "gefQ; DDB_G0289665; rasGEFQ", "gene_names_refseq": "gefQ", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor Q; RasGEF domain-containing protein Q", "protein_names_refseq": "Ras guanine nucleotide exchange factor Q", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289665); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "15875012;16086850;16234315", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP (By similarity). Seems to play a role in chemotaxis., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54H67", "ec_number_list": [], "go_molecular_function": "GO:0045159 myosin II binding;GO:0051015 actin filament binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0032486 Rap protein signal transduction;GO:0007265 Ras protein signal transduction;GO:0046686 response to cadmium ion;GO:0043520 regulation of myosin II filament assembly;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86G47-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86GL4-1", "uniprot_id": [ { "id": "NOXB_DICDI", "url": "https://www.uniprot.org/uniprot/Q86GL4", "type": "external" } ], "mass": 81239.0, "length": 698, "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit B", "gene_name": "noxB", "organism": "Cellular slime mold", "refseq_name": "flavocytochrome b large subunit", "refseq_ac": [ { "id": "XP_637386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637386", "type": "external" } ], "gene_names_uniprotkb": "noxB; DDB_G0287101", "gene_names_refseq": "noxB", "protein_names_uniprotkb": "Superoxide-generating NADPH oxidase heavy chain subunit B; 1.-.-.-; NADPH oxidase B; Superoxide-generating NADPH oxidase flavocytochrome B", "protein_names_refseq": "flavocytochrome b large subunit; superoxide-generating NADPH oxidase flavocytochrome", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287101); (R-DDI-3299685); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;15950752", "class_list": "", "function": "Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54KY4", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0020037 heme binding;GO:0016175 superoxide-generating NAD(P)H oxidase activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0006952 defense response;GO:0042742 defense response to bacterium;GO:0042554 superoxide anion generation;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86GL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86H13-1", "uniprot_id": [ { "id": "PDE4_DICDI", "url": "https://www.uniprot.org/uniprot/Q86H13", "type": "external" } ], "mass": 119447.0, "length": 1039, "protein_name": "3',5'-cyclic-AMP phosphodiesterase 4", "gene_name": "Pde4", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636379", "type": "external" } ], "gene_names_uniprotkb": "Pde4; DDB_G0289121", "gene_names_refseq": "", "protein_names_uniprotkb": "3',5'-cyclic-AMP phosphodiesterase 4; 3.1.4.53; DdPDE4; Phosphodiesterase 4; cAMP-specific phosphodiesterase 4", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289121); (ddi:DDB_G0289153); (R-DDI-165160); (R-DDI-2485179); (R-DDI-4086398); (R-DDI-418457); (R-DDI-418555); (R-DDI-445355); (R-DDI-9013422)", "pathway_count": 9, "publication_count": 4, "publication_id_list": "12429832;15875012;16644729;17040207", "class_list": "", "function": "Phosphodiesterase specific for extracellular cAMP. Involved in the degradation of extracellular cAMP specifically during multicellular development., [UniProtKB, PubMed]", "predicted_glycosites": 23, "predicted_n_glycosites": 23, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 23, "binding_glycan_count": 0, "secondary_ac_list": "Q54HY3;Q54HY4", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030552 cAMP binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0031000 response to caffeine;GO:0030587 sorocarp development;GO:0141162 negative regulation of cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q86H13-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86H98-1", "uniprot_id": [ { "id": "CHMP4_DICDI", "url": "https://www.uniprot.org/uniprot/Q86H98", "type": "external" } ], "mass": 25045.0, "length": 215, "protein_name": "Charged multivesicular body protein 4", "gene_name": "chmp4", "organism": "Cellular slime mold", "refseq_name": "SNF7 family protein", "refseq_ac": [ { "id": "XP_643404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643404", "type": "external" } ], "gene_names_uniprotkb": "chmp4; DDB_G0275573; snf7; vps32", "gene_names_refseq": "vps32", "protein_names_uniprotkb": "Charged multivesicular body protein 4; Dd-Vps32; Vacuolar protein-sorting-associated protein 32", "protein_names_refseq": "SNF7 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275573); (R-DDI-1632852); (R-DDI-917729); (R-DDI-9668328)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12097910;15708561;15875012", "class_list": "", "function": "Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q553K9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005768 endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0031468 nuclear membrane reassembly;GO:0015031 protein transport;GO:0001919 regulation of receptor recycling;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86H98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86HE5-1", "uniprot_id": [ { "id": "CF451_DICDI", "url": "https://www.uniprot.org/uniprot/Q86HE5", "type": "external" } ], "mass": 29304.0, "length": 297, "protein_name": "Counting factor 45-1", "gene_name": "cf45-1", "organism": "Cellular slime mold", "refseq_name": "component of the counting factor complex", "refseq_ac": [ { "id": "XP_646164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646164", "type": "external" } ], "gene_names_uniprotkb": "cf45-1; DDB_G0269248; ctnC", "gene_names_refseq": "cf45-1", "protein_names_uniprotkb": "Counting factor 45-1", "protein_names_refseq": "component of the counting factor complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269248)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10444594;12117815;12912898;15875012;16963635", "class_list": "", "function": "Cell-counting factor that limits the maximum size of the multicellular structure during aggregation., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q55DG7", "ec_number_list": [], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007165 signal transduction;GO:0098609 cell-cell adhesion;GO:0042593 glucose homeostasis;GO:0042742 defense response to bacterium;GO:0031640 killing of cells of another organism", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q86HE5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86HN7-1", "uniprot_id": [ { "id": "PLK_DICDI", "url": "https://www.uniprot.org/uniprot/Q86HN7", "type": "external" } ], "mass": 113599.0, "length": 978, "protein_name": "Probable serine/threonine-protein kinase PLK", "gene_name": "PLK", "organism": "Cellular slime mold", "refseq_name": "polo family protein kinase", "refseq_ac": [ { "id": "XP_644113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644113", "type": "external" } ], "gene_names_uniprotkb": "PLK; DDB_G0274503", "gene_names_refseq": "plk", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase PLK; 2.7.11.1; Polo-like kinase", "protein_names_refseq": "polo family protein kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274503); (R-DDI-156711); (R-DDI-162658); (R-DDI-174178); (R-DDI-176412); (R-DDI-2299718); (R-DDI-2500257); (R-DDI-2565942); (R-DDI-6804115); (R-DDI-68884); (R-DDI-69601); (R-DDI-9648025)", "pathway_count": 12, "publication_count": 3, "publication_id_list": "12097910;15548420;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q555F6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0000776 kinetochore", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86HN7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86I44-1", "uniprot_id": [ { "id": "LIMF_DICDI", "url": "https://www.uniprot.org/uniprot/Q86I44", "type": "external" } ], "mass": 22734.0, "length": 197, "protein_name": "LIM domain-containing protein F", "gene_name": "limF", "organism": "Cellular slime mold", "refseq_name": "LIM-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_643821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643821", "type": "external" } ], "gene_names_uniprotkb": "limF; DDB_G0275157", "gene_names_refseq": "limF", "protein_names_uniprotkb": "LIM domain-containing protein F", "protein_names_refseq": "LIM-type zinc finger-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275157)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;15962002", "class_list": "", "function": "Involved in the regulation of phagocytosis. May repress ChLim and activate rab21., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q553Z0", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0001891 phagocytic cup", "go_biological_process": "GO:0046847 filopodium assembly;GO:0006909 phagocytosis;GO:0050766 positive regulation of phagocytosis;GO:0030866 cortical actin cytoskeleton organization;GO:1902351 response to imidacloprid", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86I44-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86I79-1", "uniprot_id": [ { "id": "PSCA_DICDI", "url": "https://www.uniprot.org/uniprot/Q86I79", "type": "external" } ], "mass": 56873.0, "length": 522, "protein_name": "Penicillin-sensitive carboxypeptidase A", "gene_name": "pscA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_645397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645397", "type": "external" } ], "gene_names_uniprotkb": "pscA; DDB_G0271902", "gene_names_refseq": "pscA", "protein_names_uniprotkb": "Penicillin-sensitive carboxypeptidase A; 3.4.16.4", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271902)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;12843630;15875012", "class_list": "", "function": "Carboxypeptidase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55AF7", "ec_number_list": [], "go_molecular_function": "GO:0004185 serine-type carboxypeptidase activity;GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0030163 protein catabolic process;GO:0000270 peptidoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86I79-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86IA3-1", "uniprot_id": [ { "id": "PDI1_DICDI", "url": "https://www.uniprot.org/uniprot/Q86IA3", "type": "external" } ], "mass": 39905.0, "length": 363, "protein_name": "Protein disulfide-isomerase 1", "gene_name": "pdi1", "organism": "Cellular slime mold", "refseq_name": "protein disulfide isomerase", "refseq_ac": [ { "id": "XP_643357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643357", "type": "external" } ], "gene_names_uniprotkb": "pdi1; DDB_G0276141", "gene_names_refseq": "pdi1", "protein_names_uniprotkb": "Protein disulfide-isomerase 1; 5.3.4.1; PDI1", "protein_names_refseq": "protein disulfide isomerase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276141)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;15875012;16926386;9428745", "class_list": "", "function": "Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15735;Q552H4", "ec_number_list": [], "go_molecular_function": "GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0005811 lipid droplet;GO:0045335 phagocytic vesicle;GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q86IA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86IH1-1", "uniprot_id": [ { "id": "HBX4_DICDI", "url": "https://www.uniprot.org/uniprot/Q86IH1", "type": "external" } ], "mass": 84487.0, "length": 740, "protein_name": "Homeobox protein 4", "gene_name": "hbx4", "organism": "Cellular slime mold", "refseq_name": "homeodomain containing protein", "refseq_ac": [ { "id": "XP_644890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644890", "type": "external" } ], "gene_names_uniprotkb": "hbx4; DDB_G0272967", "gene_names_refseq": "hbx4", "protein_names_uniprotkb": "Homeobox protein 4; DdHbx-4", "protein_names_refseq": "homeodomain containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272967)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Putative transcription factor., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q559C6", "ec_number_list": [], "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0000281 mitotic cytokinesis;GO:1901262 negative regulation of sorocarp spore cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86IH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86IV5-1", "uniprot_id": [ { "id": "CTNA_DICDI", "url": "https://www.uniprot.org/uniprot/Q86IV5", "type": "external" } ], "mass": 26659.0, "length": 258, "protein_name": "Countin-1", "gene_name": "ctnA", "organism": "Cellular slime mold", "refseq_name": "component of the counting factor complex", "refseq_ac": [ { "id": "XP_643887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643887", "type": "external" } ], "gene_names_uniprotkb": "ctnA; DDB_G0274597", "gene_names_refseq": "ctnA", "protein_names_uniprotkb": "Countin-1", "protein_names_refseq": "component of the counting factor complex", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274597)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10444594;11090633;11737154;12097910;12117815;12912898;15875012;16963635", "class_list": "", "function": "Cell-counting factor that limits the maximum size of the multicellular structure. May down-regulate the expression of gp24, which mediates cell adhesion., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q556C3;Q9U7C4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0098727 maintenance of cell number;GO:0007162 negative regulation of cell adhesion;GO:0042593 glucose homeostasis;GO:0001678 intracellular glucose homeostasis;GO:0040015 negative regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q86IV5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86IX1-1", "uniprot_id": [ { "id": "DST1_DICDI", "url": "https://www.uniprot.org/uniprot/Q86IX1", "type": "external" } ], "mass": 81572.0, "length": 737, "protein_name": "Serine/threonine-protein kinase dst1", "gene_name": "dst1", "organism": "Cellular slime mold", "refseq_name": "STE20 family protein kinase", "refseq_ac": [ { "id": "XP_643908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643908", "type": "external" } ], "gene_names_uniprotkb": "dst1; DDB_G0274593; dstA", "gene_names_refseq": "dst1", "protein_names_uniprotkb": "Serine/threonine-protein kinase dst1; 2.7.11.1", "protein_names_refseq": "STE20 family protein kinase; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274593); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12097910;15875012;16842885", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q556A2", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007165 signal transduction;GO:0035556 intracellular signal transduction;GO:0043408 regulation of MAPK cascade;GO:0012501 programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86IX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86IZ4-1", "uniprot_id": [ { "id": "IPP2_DICDI", "url": "https://www.uniprot.org/uniprot/Q86IZ4", "type": "external" } ], "mass": 31091.0, "length": 261, "protein_name": "Protein phosphatase inhibitor 2", "gene_name": "dpiA", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase inhibitor 2", "refseq_ac": [ { "id": "XP_643942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643942", "type": "external" } ], "gene_names_uniprotkb": "dpiA; DDB_G0274315", "gene_names_refseq": "dpiA", "protein_names_uniprotkb": "Protein phosphatase inhibitor 2; DdI-2; IPP-2", "protein_names_refseq": "protein phosphatase inhibitor 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274315)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;17336445", "class_list": "", "function": "Inhibitor of protein-phosphatase 1 (PP1)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q555W8", "ec_number_list": [], "go_molecular_function": "GO:0019903 protein phosphatase binding;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86IZ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86JF2-1", "uniprot_id": [ { "id": "LVSB_DICDI", "url": "https://www.uniprot.org/uniprot/Q86JF2", "type": "external" } ], "mass": 463997.0, "length": 4118, "protein_name": "BEACH domain-containing protein lvsB", "gene_name": "lvsB", "organism": "Cellular slime mold", "refseq_name": "BEACH domain-containing protein", "refseq_ac": [ { "id": "XP_645615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645615", "type": "external" } ], "gene_names_uniprotkb": "lvsB; DDB_G0271504", "gene_names_refseq": "lvsB", "protein_names_uniprotkb": "BEACH domain-containing protein lvsB", "protein_names_refseq": "BEACH domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271504)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11854420;12097910;12210762;15875012;17488289;17606989", "class_list": "", "function": "Involved in negative regulation of lysosome biogenesis, by limiting the heterotypic fusion of early endosomes and postlysosomal compartments., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q55AT1;Q8IHL0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0016020 membrane;GO:0005764 lysosome;GO:0032010 phagolysosome;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006970 response to osmotic stress;GO:0007040 lysosome organization;GO:0009306 protein secretion;GO:0097494 regulation of vesicle size;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q86JF2-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86JJ0-1", "uniprot_id": [ { "id": "TRM61_DICDI", "url": "https://www.uniprot.org/uniprot/Q86JJ0", "type": "external" } ], "mass": 35264.0, "length": 312, "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trmt61a", "gene_name": "trmt61a", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "trmt61a; DDB_G0271512; trm61", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trmt61a; 2.1.1.220; tRNA(m1A58)-methyltransferase subunit trmt61A; tRNA(m1A58)MTase subunit trmt61A", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271512)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097910;15875012;3769915", "class_list": "", "function": "Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55AZ7", "ec_number_list": [ { "id": "2.1.1.220", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.220", "type": "external" } ], "go_molecular_function": "GO:0140098 catalytic activity, acting on RNA;GO:0160107 tRNA (adenine(58)-N1)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031515 tRNA (m1A) methyltransferase complex", "go_biological_process": "GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86JJ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86JM7-1", "uniprot_id": [ { "id": "P2XA_DICDI", "url": "https://www.uniprot.org/uniprot/Q86JM7", "type": "external" } ], "mass": 42186.0, "length": 378, "protein_name": "P2X receptor A", "gene_name": "p2xA", "organism": "Cellular slime mold", "refseq_name": "P2X receptor", "refseq_ac": [ { "id": "XP_645378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645378", "type": "external" } ], "gene_names_uniprotkb": "p2xA; DDB_G0272004", "gene_names_refseq": "p2xA", "protein_names_uniprotkb": "P2X receptor A; DdP2X; P2XA", "protein_names_refseq": "P2X receptor ATP-gated ion channel; P2X receptor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272004); (R-DDI-139853); (R-DDI-418346); (R-DDI-6798695); (R-DDI-844456)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "12097910;15875012;17625565;18486207;19833731", "class_list": "", "function": "P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Inward currents evoked by intracellular ATP and ATP analogs. Exclusively selective for ATP over other nucleotides. Insensitive to P2 receptor antagonists PPADS, suramin and 2',3'-O-(2,4,6-trinitrophenyl)-ATP but inhibited by nanomolar concentrations of copper and sodium ion. More permeable to ammonium than either sodium or potassium ions and less permeable to choline. It has been reported that p2xA is not essential for osmoregulation (PubMed:19833731), however this information is in contradiction with another source (PubMed:17625565) which indicates that p2xA is required for osmoregulation. Found to be permeable to chloride ions. Inhibited by copper and sodium ions., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55A88", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0015276 ligand-gated monoatomic ion channel activity;GO:0005095 GTPase inhibitor activity;GO:0031267 small GTPase binding;GO:0035381 ATP-gated ion channel activity", "go_cellular_component": "GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0006811 monoatomic ion transport;GO:0009992 intracellular water homeostasis;GO:0031340 positive regulation of vesicle fusion;GO:0035590 purinergic nucleotide receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q86JM7-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86JP3-1", "uniprot_id": [ { "id": "RAB5A_DICDI", "url": "https://www.uniprot.org/uniprot/Q86JP3", "type": "external" } ], "mass": 22319.0, "length": 201, "protein_name": "Ras-related protein Rab-5A", "gene_name": "rab5A", "organism": "Cellular slime mold", "refseq_name": "Rab GTPase", "refseq_ac": [ { "id": "XP_645357", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645357", "type": "external" } ], "gene_names_uniprotkb": "rab5A; DDB_G0271984", "gene_names_refseq": "rab5A", "protein_names_uniprotkb": "Ras-related protein Rab-5A", "protein_names_refseq": "Rab GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271984); (R-DDI-6798695); (R-DDI-8873719); (R-DDI-8876198)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Required for the fusion of plasma membranes and early endosomes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55AA9", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0010008 endosome membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:1905162 regulation of phagosome maturation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86JP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86K43-1", "uniprot_id": [ { "id": "Q86K43_DICDI", "url": "https://www.uniprot.org/uniprot/Q86K43", "type": "external" } ], "mass": 40236.0, "length": 349, "protein_name": "Endonuclease III homolog", "gene_name": "NTH1", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_642760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642760", "type": "external" } ], "gene_names_uniprotkb": "NTH1; DDB_G0277247; apnB", "gene_names_refseq": "apnB", "protein_names_uniprotkb": "Endonuclease III homolog; 3.2.2.-; 4.2.99.18; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277247); (R-DDI-110329); (R-DDI-110357)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54ZV6", "ec_number_list": [ { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "3.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006289 nucleotide-excision repair;GO:0006285 base-excision repair, AP site formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q86K43-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86KB1-1", "uniprot_id": [ { "id": "ADCB_DICDI", "url": "https://www.uniprot.org/uniprot/Q86KB1", "type": "external" } ], "mass": 70145.0, "length": 617, "protein_name": "Arrestin domain-containing protein B", "gene_name": "adcB", "organism": "Cellular slime mold", "refseq_name": "C2 calcium-dependent membrane targeting domain-containing protein", "refseq_ac": [ { "id": "XP_644234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644234", "type": "external" } ], "gene_names_uniprotkb": "adcB; DDB_G0274395", "gene_names_refseq": "adcB", "protein_names_uniprotkb": "Arrestin domain-containing protein B", "protein_names_refseq": "C2 calcium-dependent membrane targeting domain-containing protein; SAM domain-containing protein; arrestin domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274395)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554T9", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0008603 cAMP-dependent protein kinase regulator activity;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0051702 biological process involved in interaction with symbiont;GO:0002031 G protein-coupled receptor internalization;GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0031152 aggregation involved in sorocarp development;GO:0110094 polyphosphate-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86KB1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86KF9-1", "uniprot_id": [ { "id": "SPHKA_DICDI", "url": "https://www.uniprot.org/uniprot/Q86KF9", "type": "external" } ], "mass": 70024.0, "length": 624, "protein_name": "Sphingosine kinase A", "gene_name": "sgkA", "organism": "Cellular slime mold", "refseq_name": "sphingosine kinase", "refseq_ac": [ { "id": "XP_645126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645126", "type": "external" } ], "gene_names_uniprotkb": "sgkA; DDB_G0272522; SK; SPHK", "gene_names_refseq": "sgkA", "protein_names_uniprotkb": "Sphingosine kinase A; 2.7.1.91; SK A; SPK A", "protein_names_refseq": "sphingosine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272522); (R-DDI-1483206); (R-DDI-1660661); (R-DDI-390471); (R-DDI-5218921); (R-DDI-9009391); (R-DDI-9833482)", "pathway_count": 7, "publication_count": 3, "publication_id_list": "12097910;15643073;15875012", "class_list": "", "function": "Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), which probably acts intracellularly as a second messenger perhaps by promoting cell proliferation. Overexpression of sgkA leads to increased growth rates on solid media and an increased resistance to the antitumor agents cisplatin and carboplatin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q559I0", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.91", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.91", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008481 sphingosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031143 pseudopodium", "go_biological_process": "GO:1904643 response to curcumin;GO:0046512 sphingosine biosynthetic process;GO:0006648 dihydrosphingosine-1-P pathway;GO:1903666 positive regulation of asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86KF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86KI1-1", "uniprot_id": [ { "id": "AP2A2_DICDI", "url": "https://www.uniprot.org/uniprot/Q86KI1", "type": "external" } ], "mass": 110700.0, "length": 989, "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "ap2a1-1; ap2a1-2", "organism": "Cellular slime mold", "refseq_name": "adaptor-related protein complex 2, alpha subunit", "refseq_ac": [ { "id": "XP_644619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644619", "type": "external" } ], "gene_names_uniprotkb": "ap2a1-1; ap2a1-2; DDB_G0273439; DDB_G0273501", "gene_names_refseq": "ap2a1-1", "protein_names_uniprotkb": "AP-2 complex subunit alpha-2; 100 kDa coated vesicle protein C; Adaptor protein complex AP-2 subunit alpha-2; Adaptor-related protein complex 2 subunit alpha-2; Alpha-adaptin C; Alpha2-adaptin; Clathrin assembly protein complex 2 alpha-C large chain; Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit", "protein_names_refseq": "adaptor-related protein complex 2, alpha subunit; alpha adaptin", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273439); (ddi:DDB_G0273501); (R-DDI-437239); (R-DDI-6798695); (R-DDI-8856825); (R-DDI-8856828); (R-DDI-8866427); (R-DDI-8964038)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q557K4;Q557L6", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030136 clathrin-coated vesicle;GO:0030122 AP-2 adaptor complex;GO:0030132 clathrin coat of coated pit;GO:0000331 contractile vacuole", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0009992 intracellular water homeostasis;GO:0072583 clathrin-dependent endocytosis;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q86KI1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86KR9-1", "uniprot_id": [ { "id": "P4HA_DICDI", "url": "https://www.uniprot.org/uniprot/Q86KR9", "type": "external" } ], "mass": 33348.0, "length": 284, "protein_name": "Prolyl 4-hydroxylase subunit alpha", "gene_name": "phyA", "organism": "Cellular slime mold", "refseq_name": "prolyl 4-hydroxylase", "refseq_ac": [ { "id": "XP_642496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642496", "type": "external" } ], "gene_names_uniprotkb": "phyA; DDB_G0277759; p4h1", "gene_names_refseq": "phyA", "protein_names_uniprotkb": "Prolyl 4-hydroxylase subunit alpha; 1.14.11.-; Prolyl 4-hydrolase", "protein_names_refseq": "prolyl 4-hydroxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277759)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11358877;12097910;15238247;15705570;15875012", "class_list": "", "function": "Catalyzes the post-translational formation of 4-hydroxyproline. Probably hydroxylates skp1 on Pro-143., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54Z57", "ec_number_list": [ { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" } ], "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0031418 L-ascorbic acid binding;GO:0031543 peptidyl-proline dioxygenase activity;GO:0031545 peptidyl-proline 4-dioxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0071456 cellular response to hypoxia;GO:0072592 oxygen metabolic process;GO:0010265 SCF complex assembly;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q86KR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86L04-1", "uniprot_id": [ { "id": "TRAP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q86L04", "type": "external" } ], "mass": 80179.0, "length": 711, "protein_name": "TNF receptor-associated protein 1 homolog, mitochondrial", "gene_name": "trap1", "organism": "Cellular slime mold", "refseq_name": "heat shock protein Hsp90 family protein", "refseq_ac": [ { "id": "XP_642968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642968", "type": "external" } ], "gene_names_uniprotkb": "trap1; DDB_G0276947", "gene_names_refseq": "trap1", "protein_names_uniprotkb": "TNF receptor-associated protein 1 homolog, mitochondrial; TNFR-associated protein 1 homolog; Trap1 homolog", "protein_names_refseq": "heat shock protein Hsp90 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276947); (R-DDI-71403)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "12097910;12372338;15507488;15652353;15652354;15875012", "class_list": "", "function": "Chaperone that expresses an ATPase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q550G4;Q8MYB0", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005730 nucleolus;GO:0005743 mitochondrial inner membrane;GO:0005856 cytoskeleton;GO:0005938 cell cortex;GO:0031160 spore wall", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0006457 protein folding;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q86L04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q86L14-1", "uniprot_id": [ { "id": "PUR9_DICDI", "url": "https://www.uniprot.org/uniprot/Q86L14", "type": "external" } ], "mass": 59087.0, "length": 542, "protein_name": "Bifunctional purine biosynthesis protein purH", "gene_name": "purH", "organism": "Cellular slime mold", "refseq_name": "AICAR transformylase / IMP cyclohydrolase", "refseq_ac": [ { "id": "XP_642943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642943", "type": "external" } ], "gene_names_uniprotkb": "purH; DDB_G0277087", "gene_names_refseq": "purH", "protein_names_uniprotkb": "Bifunctional purine biosynthesis protein purH; AICAR transformylase; ATIC; IMP synthase; Inosinicase", "protein_names_refseq": "AICAR transformylase / IMP cyclohydrolase; inosine monophosphate cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277087); (R-DDI-73817)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;16926386", "class_list": "", "function": "Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Also catalyzes the cyclization of FAICAR to IMP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q550I9", "ec_number_list": [ { "id": "2.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.3", "type": "external" }, { "id": "3.5.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.10", "type": "external" } ], "go_molecular_function": "GO:0003937 IMP cyclohydrolase activity;GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006164 purine nucleotide biosynthetic process;GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q86L14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8I0F4-1", "uniprot_id": [ { "id": "LIS1_DICDI", "url": "https://www.uniprot.org/uniprot/Q8I0F4", "type": "external" } ], "mass": 46576.0, "length": 419, "protein_name": "Lissencephaly-1 homolog", "gene_name": "lis1", "organism": "Cellular slime mold", "refseq_name": "WD40 repeat-containing protein", "refseq_ac": [ { "id": "XP_636715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636715", "type": "external" } ], "gene_names_uniprotkb": "lis1; DDB_G0288375", "gene_names_refseq": "lis1", "protein_names_uniprotkb": "Lissencephaly-1 homolog; DdLIS1", "protein_names_refseq": "WD40 repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288375)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15800059;15875012", "class_list": "", "function": "Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the coupling of the nucleus and centrosome and dynein/dynactin-mediated interactions of microtubule tips with the cell cortex., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54J15", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0031267 small GTPase binding;GO:0070840 dynein complex binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0031592 centrosomal corona;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule", "go_biological_process": "GO:0030154 cell differentiation;GO:0051301 cell division;GO:0006909 phagocytosis;GO:0000132 establishment of mitotic spindle orientation;GO:0051642 centrosome localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8I0F4-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8I7P3-1", "uniprot_id": [ { "id": "Q8I7P3_DICDI", "url": "https://www.uniprot.org/uniprot/Q8I7P3", "type": "external" } ], "mass": 89414.0, "length": 787, "protein_name": "inositol-polyphosphate 5-phosphatase", "gene_name": "Dd5P4", "organism": "Cellular slime mold", "refseq_name": "RhoGAP domain-containing protein", "refseq_ac": [ { "id": "XP_647668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647668", "type": "external" } ], "gene_names_uniprotkb": "Dd5P4; DDB_G0267462", "gene_names_refseq": "Dd5P4", "protein_names_uniprotkb": "inositol-polyphosphate 5-phosphatase; 3.1.3.56", "protein_names_refseq": "RhoGAP domain-containing protein; inositol 5-phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267462); (R-DDI-1660499); (R-DDI-1660514); (R-DDI-1855183); (R-DDI-1855204); (R-DDI-9013423)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55F65", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "2.7.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.134", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" } ], "go_molecular_function": "GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445 inositol-polyphosphate 5-phosphatase activity;GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0030670 phagocytic vesicle membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0006911 phagocytosis, engulfment;GO:0007165 signal transduction;GO:0050829 defense response to Gram-negative bacterium;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8I7P3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8I7T3-1", "uniprot_id": [ { "id": "SADA_DICDI", "url": "https://www.uniprot.org/uniprot/Q8I7T3", "type": "external" } ], "mass": 104675.0, "length": 952, "protein_name": "Substrate-adhesion molecule", "gene_name": "sadA", "organism": "Cellular slime mold", "refseq_name": "substrate adhesion molecule", "refseq_ac": [ { "id": "XP_636687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636687", "type": "external" } ], "gene_names_uniprotkb": "sadA; DDB_G0288511", "gene_names_refseq": "sadA", "protein_names_uniprotkb": "Substrate-adhesion molecule", "protein_names_refseq": "substrate adhesion molecule", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288511); (R-DDI-114608); (R-DDI-1474228); (R-DDI-1566977); (R-DDI-2129379); (R-DDI-3000178)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "12499361;15875012", "class_list": "", "function": "Involved in substrate adhesion, myosin-independent cytokinesis, organization of actin cytoskeleton, and phagocytosis., [UniProtKB, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q54IT9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0006909 phagocytosis;GO:0000902 cell morphogenesis;GO:0050821 protein stabilization;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8I7T3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8I8U2-1", "uniprot_id": [ { "id": "AP1G_DICDI", "url": "https://www.uniprot.org/uniprot/Q8I8U2", "type": "external" } ], "mass": 99625.0, "length": 895, "protein_name": "AP-1 complex subunit gamma", "gene_name": "ap1g1", "organism": "Cellular slime mold", "refseq_name": "AP-1 complex gamma 1 subunit", "refseq_ac": [ { "id": "XP_640382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640382", "type": "external" } ], "gene_names_uniprotkb": "ap1g1; DDB_G0281957; aptC", "gene_names_refseq": "ap1g1", "protein_names_uniprotkb": "AP-1 complex subunit gamma; Adaptor protein complex AP-1 subunit gamma; Adaptor-related protein complex 1 subunit gamma; Clathrin assembly protein complex 1 gamma large chain; Gamma1-adaptin", "protein_names_refseq": "AP-1 complex gamma 1 subunit; clathrin-adaptor gamma chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281957); (R-DDI-432720)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12802059;15875012;16478785", "class_list": "", "function": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q54T69", "ec_number_list": [], "go_molecular_function": "GO:0030276 clathrin binding;GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030121 AP-1 adaptor complex;GO:0030130 clathrin coat of trans-Golgi network vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006895 Golgi to endosome transport;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8I8U2-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8IS16-1", "uniprot_id": [ { "id": "GEFH_DICDI", "url": "https://www.uniprot.org/uniprot/Q8IS16", "type": "external" } ], "mass": 69714.0, "length": 604, "protein_name": "Ras guanine nucleotide exchange factor H", "gene_name": "gefH", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor", "refseq_ac": [ { "id": "XP_642834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642834", "type": "external" } ], "gene_names_uniprotkb": "gefH; DDB_G0276963; rasGEFH", "gene_names_refseq": "gefH", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor H; RasGEF domain-containing protein H", "protein_names_refseq": "Ras guanine nucleotide exchange factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276963); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "12097910;15875012;16086850;20493808", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP (PubMed:20493808). Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808). The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q550U8", "ec_number_list": [], "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:1905742 Ras guanyl-nucleotide exchange factor complex", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0007265 Ras protein signal transduction;GO:0031152 aggregation involved in sorocarp development;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8IS16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8IS18-1", "uniprot_id": [ { "id": "GEFE_DICDI", "url": "https://www.uniprot.org/uniprot/Q8IS18", "type": "external" } ], "mass": 114738.0, "length": 1037, "protein_name": "Ras guanine nucleotide exchange factor E", "gene_name": "gefE", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor", "refseq_ac": [ { "id": "XP_646480", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646480", "type": "external" } ], "gene_names_uniprotkb": "gefE; DDB_G0269252; rasGEFE", "gene_names_refseq": "gefE", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor E; RasGEF domain-containing protein E", "protein_names_refseq": "Ras guanine nucleotide exchange factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269252); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "15875012;16086850;16234315", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP (By similarity). Seems to play a role in chemotaxis., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q55CK1", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:0034504 protein localization to nucleus;GO:0046956 positive phototaxis;GO:0043052 thermotaxis;GO:1903014 cellular response to differentiation-inducing factor 1", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8IS18-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8IS21-1", "uniprot_id": [ { "id": "GEFB_DICDI", "url": "https://www.uniprot.org/uniprot/Q8IS21", "type": "external" } ], "mass": 174053.0, "length": 1529, "protein_name": "Ras guanine nucleotide exchange factor B", "gene_name": "gefB", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor", "refseq_ac": [ { "id": "XP_646271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646271", "type": "external" } ], "gene_names_uniprotkb": "gefB; DDB_G0269222; rasGEFB", "gene_names_refseq": "gefB", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor B; RasGEF domain-containing protein B", "protein_names_refseq": "Ras guanine nucleotide exchange factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269222); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 5, "publication_id_list": "11102804;12854977;15740584;15875012;16086850", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP (By similarity). Involved in phagocytosis, fluid-phase endocytosis, regulation of macropinocytosis and control of cell movement., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55D60;Q9GQC2", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031143 pseudopodium", "go_biological_process": "GO:0007015 actin filament organization;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:2000145 regulation of cell motility;GO:0006909 phagocytosis;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8IS21-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MLZ3-1", "uniprot_id": [ { "id": "PDE5_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MLZ3", "type": "external" } ], "mass": 97992.0, "length": 867, "protein_name": "cGMP-dependent 3',5'-cGMP phosphodiesterase A", "gene_name": "pdeD", "organism": "Cellular slime mold", "refseq_name": "beta-lactamase domain-containing protein", "refseq_ac": [ { "id": "XP_644314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644314", "type": "external" } ], "gene_names_uniprotkb": "pdeD; DDB_G0274383; gbpA; pde5", "gene_names_refseq": "pdeD", "protein_names_uniprotkb": "cGMP-dependent 3',5'-cGMP phosphodiesterase A; 3.1.4.35; Cyclic GMP-binding protein A; DdPDE5; Phosphodiesterase 5; Phosphodiesterase D", "protein_names_refseq": "beta-lactamase domain-containing protein; cGMP-specific phosphodiesterase; cGMP-stimulated cGMP phosphodiesterase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274383)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12011437;12097910;12198158;12429831;12429832;12574165;15875012;17040207", "class_list": "", "function": "Phosphodiesterase specific for cGMP, which is activated by cGMP but not by cAMP (Probable) (PubMed:12429831, PubMed:12429832). Involved in the degradation of intracellular cGMP, contributes to the control of cGMP signals (PubMed:12198158, PubMed:12429832)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554K9", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" } ], "go_molecular_function": "GO:0034236 protein kinase A catalytic subunit binding;GO:0046872 metal ion binding;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0030552 cAMP binding;GO:0030553 cGMP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0072697 protein localization to cell cortex;GO:0007165 signal transduction;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q8MLZ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MM62-1", "uniprot_id": [ { "id": "PDE6_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MM62", "type": "external" } ], "mass": 124924.0, "length": 1096, "protein_name": "cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B", "gene_name": "pdeE", "organism": "Cellular slime mold", "refseq_name": "beta-lactamase domain-containing protein", "refseq_ac": [ { "id": "XP_643272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643272", "type": "external" } ], "gene_names_uniprotkb": "pdeE; DDB_G0276027; gbpB; pde6", "gene_names_refseq": "pdeE", "protein_names_uniprotkb": "cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B; 3.1.4.35; 3.1.4.53; Cyclic GMP-binding protein B; DdPDE6; PdeE; Phosphodiesterase 6; Phosphodiesterase E", "protein_names_refseq": "beta-lactamase domain-containing protein; cAMP/cGMP-stimulated cAMP/cGMP phosphodiesterase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276027)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12011437;12097910;12198158;12429832;12574165;15875012;17040207", "class_list": "", "function": "Dual specificity cAMP and cGMP phosphodiesterase with marked preference for cyclic AMP, which is activated by cAMP and cGMP. Likely functions as a cAMP-stimulated cAMP-phosphodiesterase which may play a role in regulating the cAMP relay response., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q552E1", "ec_number_list": [ { "id": "3.1.4.35", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35", "type": "external" }, { "id": "3.1.4.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53", "type": "external" } ], "go_molecular_function": "GO:0034236 protein kinase A catalytic subunit binding;GO:0046872 metal ion binding;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0030552 cAMP binding;GO:0030553 cGMP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "GO:0072697 protein localization to cell cortex;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0061120 regulation of positive chemotaxis to cAMP by DIF-1;GO:0140582 adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q8MM62-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MML5-1", "uniprot_id": [ { "id": "PAXB_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MML5", "type": "external" } ], "mass": 62330.0, "length": 569, "protein_name": "Paxillin-B", "gene_name": "paxB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644036", "type": "external" } ], "gene_names_uniprotkb": "paxB; DDB_G0274109", "gene_names_refseq": "paxB", "protein_names_uniprotkb": "Paxillin-B", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274109); (R-DDI-8849471)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12097910;15875012;16155255", "class_list": "", "function": "Required for cell-substrate adhesion, cell sorting, slug migration, and cell differentiation. May function upstream of limB., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15817;Q555N0;Q8T166", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0005938 cell cortex;GO:0030175 filopodium;GO:0031941 filamentous actin;GO:0032433 filopodium tip", "go_biological_process": "GO:0006897 endocytosis;GO:0016477 cell migration;GO:0032956 regulation of actin cytoskeleton organization;GO:0000281 mitotic cytokinesis;GO:0050765 negative regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8MML5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MN58-1", "uniprot_id": [ { "id": "CLC_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MN58", "type": "external" } ], "mass": 22137.0, "length": 194, "protein_name": "Clathrin light chain", "gene_name": "clc", "organism": "Cellular slime mold", "refseq_name": "clathrin light chain", "refseq_ac": [ { "id": "XP_642650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642650", "type": "external" } ], "gene_names_uniprotkb": "clc; DDB_G0277403; clcA", "gene_names_refseq": "clc", "protein_names_uniprotkb": "Clathrin light chain", "protein_names_refseq": "clathrin light chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277403); (R-DDI-432720); (R-DDI-437239); (R-DDI-8856828); (R-DDI-8866427); (R-DDI-8964038)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "12097910;14617352;15875012;16734666;9425628", "class_list": "", "function": "Clathrin is the major protein of the polyhedral coat of coated pits and vesicles., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54ZJ2", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0032050 clathrin heavy chain binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030130 clathrin coat of trans-Golgi network vesicle;GO:0030132 clathrin coat of coated pit", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006898 receptor-mediated endocytosis;GO:0000281 mitotic cytokinesis;GO:0009992 intracellular water homeostasis;GO:0048268 clathrin coat assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8MN58-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MPQ7-1", "uniprot_id": [ { "id": "OSB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MPQ7", "type": "external" } ], "mass": 44110.0, "length": 389, "protein_name": "Oxysterol-binding protein 1", "gene_name": "osbA", "organism": "Cellular slime mold", "refseq_name": "oxysterol binding family protein, member 1", "refseq_ac": [ { "id": "XP_641237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641237", "type": "external" } ], "gene_names_uniprotkb": "osbA; DDB_G0280053", "gene_names_refseq": "osbA", "protein_names_uniprotkb": "Oxysterol-binding protein 1; OSBPa", "protein_names_refseq": "oxysterol binding family protein, member 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280053); (R-DDI-1482801); (R-DDI-192105)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12220630;15875012", "class_list": "", "function": "May play a role in the regulation of the slug-fruiting body switch., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54VW8", "ec_number_list": [], "go_molecular_function": "GO:0032934 sterol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm;GO:0071944 cell periphery", "go_biological_process": "GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MPQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MQU6-1", "uniprot_id": [ { "id": "CISYP_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MQU6", "type": "external" } ], "mass": 55749.0, "length": 492, "protein_name": "Citrate synthase, peroxisomal", "gene_name": "cshA", "organism": "Cellular slime mold", "refseq_name": "citrate synthase", "refseq_ac": [ { "id": "XP_647596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647596", "type": "external" } ], "gene_names_uniprotkb": "cshA; DDB_G0267426", "gene_names_refseq": "cshA", "protein_names_uniprotkb": "Citrate synthase, peroxisomal; 2.3.3.16", "protein_names_refseq": "citrate synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267426)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15225305;15875012", "class_list": "", "function": "Peroxisomal protein involved in the cellular biosynthesis of citrate, and required primarily for cell growth and modulation of multicellular development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55FD7", "ec_number_list": [ { "id": "2.3.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.16", "type": "external" } ], "go_molecular_function": "GO:0036440 citrate synthase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005777 peroxisome", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006897 endocytosis;GO:0005975 carbohydrate metabolic process;GO:0006909 phagocytosis;GO:0050766 positive regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MQU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MUF9-1", "uniprot_id": [ { "id": "CPLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MUF9", "type": "external" } ], "mass": 72623.0, "length": 649, "protein_name": "Putative calpain-like cysteine protease A", "gene_name": "cplA", "organism": "Cellular slime mold", "refseq_name": "calpain-like cysteine protease", "refseq_ac": [ { "id": "XP_646763", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646763", "type": "external" } ], "gene_names_uniprotkb": "cplA; DDB_G0269200; cpl", "gene_names_refseq": "cplA", "protein_names_uniprotkb": "Putative calpain-like cysteine protease A; 3.4.22.-", "protein_names_refseq": "calpain-like cysteine protease", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269200); (R-DDI-6798695)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12578394;15875012", "class_list": "", "function": "Has a weak caseinolytic activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55BR8", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MUF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MVR1-1", "uniprot_id": [ { "id": "GBPC_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MVR1", "type": "external" } ], "mass": 294127.0, "length": 2631, "protein_name": "Cyclic GMP-binding protein C", "gene_name": "gbpC", "organism": "Cellular slime mold", "refseq_name": "DEP domain-containing protein", "refseq_ac": [ { "id": "XP_635392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635392", "type": "external" } ], "gene_names_uniprotkb": "gbpC; DDB_G0291079; gefT; rasGEFT", "gene_names_refseq": "gbpC", "protein_names_uniprotkb": "Cyclic GMP-binding protein C; 2.7.11.1; Ras guanine nucleotide exchange factor T; RasGEF domain-containing protein T", "protein_names_refseq": "DEP domain-containing protein; GRAM domain-containing protein; ROCO family protein kinase; RasGEF domain-containing protein; cyclic GMP-binding protein; leucine-rich repeat-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291079)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12011437;12198158;15827084;15875012;16086850;16546177;18299345;18703517", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP (By similarity). Required for cyclic GMP-mediated chemotaxis, polarity. Plays a key role in cyclic AMP-induced myosin II translocation to the cortex. Also involved in the phosphorylation of mlkA and mlcR, either directly or via an intermediate kinase., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54F62", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0031252 cell leading edge", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0007165 signal transduction;GO:0007264 small GTPase-mediated signal transduction;GO:0051602 response to electrical stimulus;GO:0050920 regulation of chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q8MVR1-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MXY0-1", "uniprot_id": [ { "id": "AMT3_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MXY0", "type": "external" } ], "mass": 46992.0, "length": 431, "protein_name": "Ammonium transporter 3", "gene_name": "amtC", "organism": "Cellular slime mold", "refseq_name": "ammonium transporter", "refseq_ac": [ { "id": "XP_647385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647385", "type": "external" } ], "gene_names_uniprotkb": "amtC; DDB_G0267424", "gene_names_refseq": "amtC", "protein_names_uniprotkb": "Ammonium transporter 3", "protein_names_refseq": "ammonium transporter", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267424)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14686953;15875012;16188250;17951519;19108721", "class_list": "", "function": "Ammonium transporter that mediates the import of ammonium in prespore cells. Controls ammonium homeostasis during growth and development. Ammonium has been shown to function as a morphogen at multiple steps during the development. May function as an ammonia sensor that relays information concerning ammonia concentrations to the signaling pathway involved in the slug versus culmination choice and regulates prestalk gene expression., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55FZ8;Q7Z1M2", "ec_number_list": [], "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0030670 phagocytic vesicle membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0097272 ammonium homeostasis;GO:0072488 ammonium transmembrane transport;GO:0046903 secretion;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8MXY0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MY12-1", "uniprot_id": [ { "id": "MHCKC_DICDI", "url": "https://www.uniprot.org/uniprot/Q8MY12", "type": "external" } ], "mass": 86180.0, "length": 780, "protein_name": "Myosin heavy chain kinase C", "gene_name": "mhkC", "organism": "Cellular slime mold", "refseq_name": "Alpha kinase family protein", "refseq_ac": [ { "id": "XP_635600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635600", "type": "external" } ], "gene_names_uniprotkb": "mhkC; DDB_G0290687; mhckC", "gene_names_refseq": "mhkC", "protein_names_uniprotkb": "Myosin heavy chain kinase C; 2.7.11.7; MHCK-C", "protein_names_refseq": "Alpha kinase family protein; MHCK subfamily protein kinase; myosin heavy chain kinase; protein kinase, Atypical group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290687)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11278493;12139770;12475956;15875012;15987738;17371831;18559084", "class_list": "", "function": "Phosphorylates threonine at 'Thr-1823', 'Thr-1833' and 'Thr-2029' in the C-terminal tail region of myosin II heavy chain (mhcA) (By similarity). This phosphorylation is critical in actin-activated ATPase activity of the myosin and regulating the assembly and disassembly of myosin II filament. In vitro, catalytic domain phosphorylates mhcA, myelin basic protein, myosin regulatory light chain, casein and caldesmon. Drives the disassembly of myosin II filaments for efficient cytokinesis and recycling of myosin II that occurs during late cytokinesis. Can be activated in vitro by autophosphorylation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76739;Q54FQ7", "ec_number_list": [ { "id": "2.7.11.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.7", "type": "external" } ], "go_molecular_function": "GO:0045159 myosin II binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016905 myosin heavy chain kinase activity", "go_cellular_component": "GO:0005938 cell cortex;GO:0032154 cleavage furrow;GO:0005826 actomyosin contractile ring", "go_biological_process": "GO:0006935 chemotaxis;GO:0000281 mitotic cytokinesis;GO:0031037 myosin II filament disassembly;GO:1903013 response to differentiation-inducing factor 1", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q8MY12-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SSQ0-1", "uniprot_id": [ { "id": "GEFR_DICDI", "url": "https://www.uniprot.org/uniprot/Q8SSQ0", "type": "external" } ], "mass": 193133.0, "length": 1721, "protein_name": "Ras guanine nucleotide exchange factor R", "gene_name": "gefR", "organism": "Cellular slime mold", "refseq_name": "Ras guanine nucleotide exchange factor", "refseq_ac": [ { "id": "XP_643999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643999", "type": "external" } ], "gene_names_uniprotkb": "gefR; DDB_G0274605; rasGEFR", "gene_names_refseq": "gefR", "protein_names_uniprotkb": "Ras guanine nucleotide exchange factor R; RasGEF domain-containing protein R", "protein_names_refseq": "Ras guanine nucleotide exchange factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274605); (R-DDI-1169092); (R-DDI-171007); (R-DDI-193648); (R-DDI-354192); (R-DDI-381676); (R-DDI-392517); (R-DDI-5673001); (R-DDI-9013149); (R-DDI-9013423)", "pathway_count": 10, "publication_count": 6, "publication_id_list": "12097910;15352238;15875012;16086850;17380187;8793298", "class_list": "", "function": "Promotes the exchange of Ras-bound GDP by GTP. May also play a role in the activation of rasG., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q555R4", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:1903013 response to differentiation-inducing factor 1", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8SSQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SSS9-1", "uniprot_id": [ { "id": "QKGA_DICDI", "url": "https://www.uniprot.org/uniprot/Q8SSS9", "type": "external" } ], "mass": 174817.0, "length": 1553, "protein_name": "Probable serine/threonine-protein kinase qkgA", "gene_name": "qkgA-1; qkgA-2", "organism": "Cellular slime mold", "refseq_name": "ROCO family protein kinase", "refseq_ac": [ { "id": "XP_644434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644434", "type": "external" } ], "gene_names_uniprotkb": "qkgA-1; qkgA-2; DDB_G0273259; DDB_G0273635; roco2-1; roco2-2", "gene_names_refseq": "qkgA-2", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase qkgA; 2.7.11.1; Quick growth protein qkgA; Ras of complex proteins and C-terminal of roc 2", "protein_names_refseq": "ROCO family protein kinase; leucine-rich repeat-containing protein; protein kinase, TKL group; tyrosine kinase-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0273259); (ddi:DDB_G0273635); (R-DDI-3295583); (R-DDI-5213460); (R-DDI-5673000); (R-DDI-5674135); (R-DDI-5675221); (R-DDI-5675482)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "12097910;12954783;14654223;15875012", "class_list": "", "function": "Involved in growth, and during development, in aggregation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q557D4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030027 lamellipodium;GO:0032154 cleavage furrow;GO:0031143 pseudopodium;GO:1904269 cell leading edge cell cortex", "go_biological_process": "GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction;GO:0032465 regulation of cytokinesis;GO:0006997 nucleus organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8SSS9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SSY6-1", "uniprot_id": [ { "id": "SPKUL_DICDI", "url": "https://www.uniprot.org/uniprot/Q8SSY6", "type": "external" } ], "mass": 213011.0, "length": 1887, "protein_name": "Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligase", "gene_name": "DDB_G0276527", "organism": "Cellular slime mold", "refseq_name": "CAMKL family protein kinase", "refseq_ac": [ { "id": "XP_643080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643080", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0276527", "gene_names_refseq": "", "protein_names_uniprotkb": "Bifunctional serine/threonine-protein kinase/NEDD4-like E3 ubiquitin-protein ligase; HECT-type E3 ubiquitin transferase DDB_G0276527", "protein_names_refseq": "CAMKL family protein kinase; protein kinase, CAMK group; regulator of chromosome condensation domain-containing protein; ubiquitin-protein ligase domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276527)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q551N9", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0061630 ubiquitin protein ligase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8SSY6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8ST66-1", "uniprot_id": [ { "id": "ABCGI_DICDI", "url": "https://www.uniprot.org/uniprot/Q8ST66", "type": "external" } ], "mass": 166508.0, "length": 1476, "protein_name": "ABC transporter G family member 18", "gene_name": "abcG18", "organism": "Cellular slime mold", "refseq_name": "ABC transporter G family protein", "refseq_ac": [ { "id": "XP_643502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643502", "type": "external" } ], "gene_names_uniprotkb": "abcG18; DDB_G0275687; mdra2", "gene_names_refseq": "abcG18", "protein_names_uniprotkb": "ABC transporter G family member 18; ABC transporter ABCG.18; ABC transporter mdrA2", "protein_names_refseq": "ABC transporter G family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275687)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11719559;12097910;12456012;15875012", "class_list": "", "function": "Required for endocytosis and endosomal pH regulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q553B8;Q8MXM5;Q965D3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0030154 cell differentiation;GO:0048388 endosomal lumen acidification;GO:0031152 aggregation involved in sorocarp development;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8ST66-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T135-1", "uniprot_id": [ { "id": "KIF5_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T135", "type": "external" } ], "mass": 110435.0, "length": 990, "protein_name": "Kinesin-related protein 5", "gene_name": "kif5", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 5", "refseq_ac": [ { "id": "XP_643173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643173", "type": "external" } ], "gene_names_uniprotkb": "kif5; DDB_G0276369; kin5", "gene_names_refseq": "kif5", "protein_names_uniprotkb": "Kinesin-related protein 5; Kinesin family member 5; Kinesin-1", "protein_names_refseq": "kinesin family member 5", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276369)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;14623897;14641909;15875012", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). May connect microtubules to actin filaments. Associates with actin-based structures in cells and is likely involved in the organization of actin cytoskeletons in such structures., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q551S3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0051015 actin filament binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0031252 cell leading edge;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8T135-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T137-1", "uniprot_id": [ { "id": "GSHR_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T137", "type": "external" } ], "mass": 50483.0, "length": 465, "protein_name": "Glutathione reductase", "gene_name": "gsr", "organism": "Cellular slime mold", "refseq_name": "glutathione reductase", "refseq_ac": [ { "id": "XP_644939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644939", "type": "external" } ], "gene_names_uniprotkb": "gsr; DDB_G0272754", "gene_names_refseq": "gsr", "protein_names_uniprotkb": "Glutathione reductase; 1.8.1.7; GRase; GR; GSR", "protein_names_refseq": "glutathione reductase; glutathione-disulfide reductase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272754); (R-DDI-3299685); (R-DDI-499943); (R-DDI-5628897)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12097910;15875012;16678813", "class_list": "", "function": "Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol (PubMed:16678813). The amount of GSH may affect the determination of cell fate (PubMed:16678813)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q558X7", "ec_number_list": [ { "id": "1.8.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.7", "type": "external" } ], "go_molecular_function": "GO:0043295 glutathione binding;GO:0050660 flavin adenine dinucleotide binding;GO:0050661 NADP binding;GO:0004362 glutathione-disulfide reductase (NADPH) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0045454 cell redox homeostasis;GO:0006749 glutathione metabolic process;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8T137-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T1C6-1", "uniprot_id": [ { "id": "GNT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T1C6", "type": "external" } ], "mass": 49069.0, "length": 423, "protein_name": "[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase", "gene_name": "gnt1", "organism": "Cellular slime mold", "refseq_name": "GlcNAc transferase", "refseq_ac": [ { "id": "XP_643451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643451", "type": "external" } ], "gene_names_uniprotkb": "gnt1; DDB_G0275699; gnt51; gntA", "gene_names_refseq": "gnt1", "protein_names_uniprotkb": "[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase; 2.4.1.229; Glycosyltransferase GnT51; Skp1 GlcNAc-Tase; Skp1-HyPro GlcNAc-transferase; UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase; UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase", "protein_names_refseq": "GlcNAc transferase; UDP-GlcNAc:hydroxyproline polypeptide alpha-N-acetylglucosaminetransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275699)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10593934;12097910;12244115;15875012", "class_list": "glycogene;glycosyltransferase", "function": "Catalyzes the attachment of N-acetylglucosamine (GlcNAc) in alpha-linkage onto the 'hydroxyPro-143' residue of Skp1 (fpaA/fpaB). Is the first glycosyltransferase in the Skp1 HyPro modification pathway, which results in a pentasaccharide-linked 'HyPro-143'., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q553G2;Q967M5", "ec_number_list": [ { "id": "2.4.1.229", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.229", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008375 acetylglucosaminyltransferase activity;GO:0033830 Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0010265 SCF complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8T1C6-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T1E3-1", "uniprot_id": [ { "id": "DCAM_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T1E3", "type": "external" } ], "mass": 42569.0, "length": 379, "protein_name": "S-adenosylmethionine decarboxylase proenzyme", "gene_name": "amd1", "organism": "Cellular slime mold", "refseq_name": "S-adenosylmethionine decarboxylase", "refseq_ac": [ { "id": "XP_643401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643401", "type": "external" } ], "gene_names_uniprotkb": "amd1; DDB_G0275567", "gene_names_refseq": "amd1", "protein_names_uniprotkb": "S-adenosylmethionine decarboxylase proenzyme; 4.1.1.50; AdoMetDC; SAMDC", "protein_names_refseq": "S-adenosylmethionine decarboxylase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275567); (R-DDI-351202)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "S-adenosylmethionine decarboxylase is essential for the biosynthesis of spermine and spermidine. The alpha subunit contains the active site (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0M0Q1;Q553L2", "ec_number_list": [ { "id": "4.1.1.50", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.50", "type": "external" } ], "go_molecular_function": "GO:0004014 adenosylmethionine decarboxylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006597 spermine biosynthetic process;GO:0008295 spermidine biosynthetic process;GO:0009446 putrescine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8T1E3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T1G4-1", "uniprot_id": [ { "id": "LYSA_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T1G4", "type": "external" } ], "mass": 19526.0, "length": 181, "protein_name": "Lysozyme A", "gene_name": "alyA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_643739", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643739", "type": "external" } ], "gene_names_uniprotkb": "alyA; DDB_G0275123", "gene_names_refseq": "alyA", "protein_names_uniprotkb": "Lysozyme A; 1,4-beta-N-acetylmuramidase A; 3.2.1.n3", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275123)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12097910;15010511;15640146;15875012", "class_list": "glycogene;glycosylhydrolase", "function": "Has antibacterial activity against the Gram-positive bacteria B.subtilis, B.megaterium and M.luteus. No antibacterial activity detected against the Gram-positive bacterium S.aureus or against the Gram-negative bacterium E.coli. Lacks chitinase activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554H2", "ec_number_list": [], "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0060205 cytoplasmic vesicle lumen;GO:0031983 vesicle lumen", "go_biological_process": "GO:0050830 defense response to Gram-positive bacterium;GO:0006909 phagocytosis;GO:0046686 response to cadmium ion;GO:0031640 killing of cells of another organism;GO:0009253 peptidoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8T1G4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T2I8-1", "uniprot_id": [ { "id": "SEPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T2I8", "type": "external" } ], "mass": 129682.0, "length": 1167, "protein_name": "Serine/threonine-protein kinase sepA", "gene_name": "sepA", "organism": "Cellular slime mold", "refseq_name": "armadillo repeat-containing protein", "refseq_ac": [ { "id": "XP_643141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643141", "type": "external" } ], "gene_names_uniprotkb": "sepA; DDB_G0276465", "gene_names_refseq": "sepA", "protein_names_uniprotkb": "Serine/threonine-protein kinase sepA; 2.7.11.1; Septase A", "protein_names_refseq": "armadillo repeat-containing protein; protein kinase, STE group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276465); (R-DDI-2871796)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "12097910;15875012;16596165;17557329;18590548;19479821", "class_list": "", "function": "Serine/threonine-protein kinase involved in the spatial and temporal control system organizing cortical activities in mitotic and postmitotic cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q551J3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0000165 MAPK cascade;GO:0000281 mitotic cytokinesis;GO:0036089 cleavage furrow formation;GO:0030587 sorocarp development;GO:0031272 regulation of pseudopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8T2I8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T638-1", "uniprot_id": [ { "id": "DMTA_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T638", "type": "external" } ], "mass": 41619.0, "length": 363, "protein_name": "Des-methyl DIF-1 methyltransferase A", "gene_name": "dmtA", "organism": "Cellular slime mold", "refseq_name": "O-methyltransferase family 2 protein", "refseq_ac": [ { "id": "XP_636282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636282", "type": "external" } ], "gene_names_uniprotkb": "dmtA; DDB_G0289329; omt8", "gene_names_refseq": "dmtA", "protein_names_uniprotkb": "Des-methyl DIF-1 methyltransferase A; 2.1.1.-; O-methyltransferase 8", "protein_names_refseq": "O-methyltransferase family 2 protein; des-methyl-DIF-1 methyltransferase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289329); (R-DDI-209931)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11163223;11748133;15875012;16906151;20231486;9446571", "class_list": "", "function": "O-methyltransferase; part of the gene cluster that mediates the biosynthesis of DIF-1 (Differentiation Inducing Factor-1), a signal molecule involved in the differentiation of pstO (prestalk-O) cells (PubMed:9446571). The three-step process begins with the formation of (2,4,6-trihydroxyphenyl)-1-hexan-1-one (THPH) by the polyketide synthase StlB (PubMed:16906151). THPH is then dichlorinated by the flavin-dependent halogenase ChlA (PubMed:20231486). The last step of DIF-1 biosynthesis is the O-methylation of dichloro-THPH (or des-methyl-DIF-1) by the methyltransferase DmtA to yield DIF-1 (PubMed:9446571)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54HL9", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0008171 O-methyltransferase activity;GO:0106268 3,5-dichloro-THPH methyl transferase activity", "go_cellular_component": "", "go_biological_process": "GO:0045595 regulation of cell differentiation;GO:0032259 methylation;GO:0010623 programmed cell death involved in cell development;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0031148 DIF-1 biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8T638-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T7K0-1", "uniprot_id": [ { "id": "ALIX_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T7K0", "type": "external" } ], "mass": 90526.0, "length": 794, "protein_name": "ALG-2 interacting protein X", "gene_name": "alxA", "organism": "Cellular slime mold", "refseq_name": "ALG-2 interacting protein X", "refseq_ac": [ { "id": "XP_643566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643566", "type": "external" } ], "gene_names_uniprotkb": "alxA; DDB_G0275451; alx", "gene_names_refseq": "alxA", "protein_names_uniprotkb": "ALG-2 interacting protein X; Alix; Dd-Alix; DdAlix", "protein_names_refseq": "ALG-2 interacting protein X", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275451); (R-DDI-5213460)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "12097910;15276209;15708561;15757670;15875012;16766083", "class_list": "", "function": "Unknown. Required for development but not for cell death., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q552W2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0019722 calcium-mediated signaling;GO:0009653 anatomical structure morphogenesis;GO:0045881 positive regulation of sporulation resulting in formation of a cellular spore;GO:0031286 negative regulation of sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8T7K0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T869-1", "uniprot_id": [ { "id": "BIP2_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T869", "type": "external" } ], "mass": 72538.0, "length": 658, "protein_name": "Luminal-binding protein 2", "gene_name": "bip2", "organism": "Cellular slime mold", "refseq_name": "heat shock protein Hsp70 family protein", "refseq_ac": [ { "id": "XP_643155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643155", "type": "external" } ], "gene_names_uniprotkb": "bip2; DDB_G0276445", "gene_names_refseq": "", "protein_names_uniprotkb": "Luminal-binding protein 2; BiP 2", "protein_names_refseq": "heat shock protein Hsp70 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276445); (R-DDI-3371453); (R-DDI-9909505)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12097910;15875012;16926386", "class_list": "", "function": "Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q551H9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0034663 endoplasmic reticulum chaperone complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005788 endoplasmic reticulum lumen;GO:0005811 lipid droplet", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway;GO:0046689 response to mercury ion;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8T869-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T8M2-1", "uniprot_id": [ { "id": "PROF3_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T8M2", "type": "external" } ], "mass": 13315.0, "length": 126, "protein_name": "Profilin-3", "gene_name": "proC", "organism": "Cellular slime mold", "refseq_name": "profilin III", "refseq_ac": [ { "id": "XP_645626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645626", "type": "external" } ], "gene_names_uniprotkb": "proC; DDB_G0271142", "gene_names_refseq": "proC", "protein_names_uniprotkb": "Profilin-3; Profilin III", "protein_names_refseq": "profilin III", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0271142)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12097910;15875012", "class_list": "", "function": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55BI6", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0003785 actin monomer binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding", "go_cellular_component": "GO:0005938 cell cortex;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0045010 actin nucleation;GO:0030838 positive regulation of actin filament polymerization;GO:0030837 negative regulation of actin filament polymerization;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8T8M2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T9S7-1", "uniprot_id": [ { "id": "PTEN_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T9S7", "type": "external" } ], "mass": 59831.0, "length": 533, "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "gene_name": "pteN", "organism": "Cellular slime mold", "refseq_name": "3-phosphatidylinositol 3-phosphatase", "refseq_ac": [ { "id": "XP_637576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637576", "type": "external" } ], "gene_names_uniprotkb": "pteN; DDB_G0286557; ptenA", "gene_names_refseq": "pten", "protein_names_uniprotkb": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; 3.1.3.-; 3.1.3.16; 3.1.3.48; 3.1.3.67; Inositol polyphosphate 3-phosphatase; Pten 3-phosphoinositide phosphatase alpha", "protein_names_refseq": "3-phosphatidylinositol 3-phosphatase; protein tyrosine phosphatase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286557); (R-DDI-1660499); (R-DDI-1855204); (R-DDI-199418); (R-DDI-202424); (R-DDI-5689880); (R-DDI-5689896); (R-DDI-8948747); (R-DDI-8948751)", "pathway_count": 9, "publication_count": 8, "publication_id_list": "12062103;12062104;15875012;17419997;17623773;18657484;18676656;19011688", "class_list": "", "function": "Dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also functions as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring of PtdIns(3,4,5)P3/phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4)P2/phosphatidylinositol 3,4-diphosphate and PtdIns3P/phosphatidylinositol 3-phosphate with a preference for PtdIns(3,4,5)P3. Furthermore, this enzyme can also act as a cytosolic inositol 3-phosphatase acting on Ins(1,3,4,5,6)P5/inositol 1,3,4,5,6 pentakisphosphate and possibly Ins(1,3,4,5)P4/1D-myo-inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotaxis defects consistent with a reduction in PI3K activity., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54LI5;Q8T658", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032154 cleavage furrow;GO:0042995 cell projection", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0046580 negative regulation of Ras protein signal transduction;GO:0006935 chemotaxis;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q8T9S7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8T9W1-1", "uniprot_id": [ { "id": "TAGD_DICDI", "url": "https://www.uniprot.org/uniprot/Q8T9W1", "type": "external" } ], "mass": 202642.0, "length": 1825, "protein_name": "Serine protease/ABC transporter B family protein tagD", "gene_name": "tagD", "organism": "Cellular slime mold", "refseq_name": "ABC transporter B family protein", "refseq_ac": [ { "id": "XP_637863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637863", "type": "external" } ], "gene_names_uniprotkb": "tagD; DDB_G0286123", "gene_names_refseq": "tagD", "protein_names_uniprotkb": "Serine protease/ABC transporter B family protein tagD; 3.4.21.-; Serine protease/ABC transporter tagD", "protein_names_refseq": "ABC transporter B family protein; serine protease", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286123); (R-DDI-159418); (R-DDI-193368); (R-DDI-382556); (R-DDI-9754706); (R-DDI-9757110); (R-DDI-983170)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "12456012;15875012", "class_list": "", "function": "", "predicted_glycosites": 12, "predicted_n_glycosites": 11, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "Q54M85", "ec_number_list": [ { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0030154 cell differentiation;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8T9W1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8WQ85-1", "uniprot_id": [ { "id": "VILD_DICDI", "url": "https://www.uniprot.org/uniprot/Q8WQ85", "type": "external" } ], "mass": 191191.0, "length": 1704, "protein_name": "Villidin", "gene_name": "vilA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_636652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636652", "type": "external" } ], "gene_names_uniprotkb": "vilA; DDB_G0288557", "gene_names_refseq": "vilA", "protein_names_uniprotkb": "Villidin", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288557); (R-DDI-6798695)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12857859;15875012", "class_list": "", "function": "May function as a linker between membranes and the actin cytoskeleton., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "P90524;Q54IR2", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0015629 actin cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0051707 response to other organism;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:0046956 positive phototaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8WQ85-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8WQ86-1", "uniprot_id": [ { "id": "EB1_DICDI", "url": "https://www.uniprot.org/uniprot/Q8WQ86", "type": "external" } ], "mass": 56983.0, "length": 506, "protein_name": "Microtubule-associated protein RP/EB family member 1", "gene_name": "eb1", "organism": "Cellular slime mold", "refseq_name": "microtubule-associated protein EB1", "refseq_ac": [ { "id": "XP_638940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638940", "type": "external" } ], "gene_names_uniprotkb": "eb1; DDB_G0283607", "gene_names_refseq": "eb1", "protein_names_uniprotkb": "Microtubule-associated protein RP/EB family member 1; DdEB1", "protein_names_refseq": "microtubule-associated protein EB1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283607)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12134070;15875012;16782229", "class_list": "", "function": "Involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q54QT3", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0051010 microtubule plus-end binding;GO:0070840 dynein complex binding", "go_cellular_component": "GO:0031592 centrosomal corona;GO:0000235 astral microtubule;GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization;GO:0051225 spindle assembly;GO:0035372 protein localization to microtubule", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8WQ86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8WSR7-1", "uniprot_id": [ { "id": "CTNB_DICDI", "url": "https://www.uniprot.org/uniprot/Q8WSR7", "type": "external" } ], "mass": 26347.0, "length": 254, "protein_name": "Countin-2", "gene_name": "ctnB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641512", "type": "external" } ], "gene_names_uniprotkb": "ctnB; DDB_G0279797", "gene_names_refseq": "ctnB", "protein_names_uniprotkb": "Countin-2", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279797)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11737154;15875012", "class_list": "", "function": "Cell-counting factor that limits the minimum size of the multicellular structure. May up-regulate the expression of both gp24 and gp80, which mediate cell adhesion., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q54W80", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8WSR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q94464-1", "uniprot_id": [ { "id": "DYNA_DICDI", "url": "https://www.uniprot.org/uniprot/Q94464", "type": "external" } ], "mass": 96106.0, "length": 853, "protein_name": "Dynamin-A", "gene_name": "dymA", "organism": "Cellular slime mold", "refseq_name": "dynamin like protein", "refseq_ac": [ { "id": "XP_642112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642112", "type": "external" } ], "gene_names_uniprotkb": "dymA; DDB_G0277849", "gene_names_refseq": "dymA", "protein_names_uniprotkb": "Dynamin-A", "protein_names_refseq": "dynamin like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277849); (R-DDI-169911); (R-DDI-75153)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "11689422;15875012;16782229;16926386;9880338", "class_list": "", "function": "Function in membrane trafficking processes along the endo-lysosomal pathway., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54YU0", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005543 phospholipid binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016020 membrane;GO:0045171 intercellular bridge;GO:0032154 cleavage furrow", "go_biological_process": "GO:0090383 phagosome acidification;GO:0007015 actin filament organization;GO:0016559 peroxisome fission;GO:0006909 phagocytosis;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q94464-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q94465-1", "uniprot_id": [ { "id": "GCH1_DICDI", "url": "https://www.uniprot.org/uniprot/Q94465", "type": "external" } ], "mass": 26277.0, "length": 232, "protein_name": "GTP cyclohydrolase 1", "gene_name": "gchA", "organism": "Cellular slime mold", "refseq_name": "GTP cyclohydrolase I", "refseq_ac": [ { "id": "XP_636697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636697", "type": "external" } ], "gene_names_uniprotkb": "gchA; DDB_G0288481; folE; gtoC", "gene_names_refseq": "gchA", "protein_names_uniprotkb": "GTP cyclohydrolase 1; 3.5.4.16; GTP cyclohydrolase I; GTP-CH-I; GTP-CH", "protein_names_refseq": "GTP cyclohydrolase I", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288481); (R-DDI-1474151)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "15875012;16926386;8870645", "class_list": "", "function": "First enzyme in the biosynthesis of tetrahydrobiopterin (BH4) (PubMed:8870645). Catalyzes the conversion of GTP into dihydroneopterin triphosphate (7,8-dihydroneopterin 3'-triphosphate), which is subsequently catalyzed by 6-pyruvoyltetrahydropterin synthase (ptsA) and sepiapterin reductase (sprA) (PubMed:8870645)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54IV6", "ec_number_list": [ { "id": "3.5.4.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.16", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0008270 zinc ion binding;GO:0003934 GTP cyclohydrolase I activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0006979 response to oxidative stress;GO:0006729 tetrahydrobiopterin biosynthetic process;GO:0008277 regulation of G protein-coupled receptor signaling pathway;GO:0140460 response to Gram-negative bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q94465-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q94469-1", "uniprot_id": [ { "id": "G3P_DICDI", "url": "https://www.uniprot.org/uniprot/Q94469", "type": "external" } ], "mass": 36552.0, "length": 335, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "gpdA", "organism": "Cellular slime mold", "refseq_name": "NAD+-dependent glyceraldehyde phosphate dehydrogenase", "refseq_ac": [ { "id": "XP_643857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643857", "type": "external" } ], "gene_names_uniprotkb": "gpdA; DDB_G0275153", "gene_names_refseq": "gpdA", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12; GAPDH", "protein_names_refseq": "NAD+-dependent glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275153); (R-DDI-70171); (R-DDI-70263)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "12097910;15875012;16926386;8976605", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q553V4;Q869Y9", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031012 extracellular matrix;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q94469-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q94490-1", "uniprot_id": [ { "id": "UBCB_DICDI", "url": "https://www.uniprot.org/uniprot/Q94490", "type": "external" } ], "mass": 16809.0, "length": 148, "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "organism": "Cellular slime mold", "refseq_name": "ubiquitin-conjugating enzyme E2", "refseq_ac": [ { "id": "XP_639901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639901", "type": "external" } ], "gene_names_uniprotkb": "ubcB; DDB_G0284865", "gene_names_refseq": "ubcB", "protein_names_uniprotkb": "Ubiquitin conjugating enzyme E2 B; 2.3.2.23; E2 ubiquitin-conjugating enzyme B; UBC1", "protein_names_refseq": "ubiquitin-conjugating enzyme E2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0284865); (R-DDI-1169408); (R-DDI-141430); (R-DDI-174048); (R-DDI-174084); (R-DDI-174154); (R-DDI-174178); (R-DDI-174184); (R-DDI-176407); (R-DDI-176408); (R-DDI-176409); (R-DDI-176412); (R-DDI-179409); (R-DDI-2467813); (R-DDI-2559582); (R-DDI-69017); (R-DDI-8866652); (R-DDI-8866654); (R-DDI-9033241); (R-DDI-936440); (R-DDI-983168); (R-DDI-9833482); (R-DDI-9909505); (R-DDI-9954709); (R-DDI-9954716)", "pathway_count": 25, "publication_count": 3, "publication_id_list": "15875012;9348538;9832508", "class_list": "", "function": "Involved in protein ubiquitination and degradation during development. Mediates protein ubiquitination at the mound and finger stage required for subsequent development and may be an essential component of the developmental transition between the induction of postaggregative gene expression and subsequent cell-type differentiation and morphogenesis. ubcB and ubpB differentially control ubiquitination/deubiquitination and degradation of mkkA protein in a cell-type-specific and temporally regulated manner., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54P16", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "3.1.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.2.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.6", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "6.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.64", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.4.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.37", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" } ], "go_molecular_function": "GO:0004842 ubiquitin-protein transferase activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q94490-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q94502-1", "uniprot_id": [ { "id": "GANAB_DICDI", "url": "https://www.uniprot.org/uniprot/Q94502", "type": "external" } ], "mass": 108772.0, "length": 943, "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "modA", "organism": "Cellular slime mold", "refseq_name": "alpha-glucosidase II", "refseq_ac": [ { "id": "XP_646169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646169", "type": "external" } ], "gene_names_uniprotkb": "modA; DDB_G0269154; ganab", "gene_names_refseq": "modA", "protein_names_uniprotkb": "Neutral alpha-glucosidase AB; 3.2.1.207; Alpha-glucosidase 2; Glucosidase II subunit alpha; Protein post-translational modification mutant A", "protein_names_refseq": "alpha-glucosidase II", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269154)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;9397534", "class_list": "glycogene;glycosylhydrolase", "function": "Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from N-linked oligosaccharides on newly synthesized glycoproteins., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q55DG2", "ec_number_list": [ { "id": "3.2.1.207", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.207", "type": "external" } ], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0033919 glucan 1,3-alpha-glucosidase activity;GO:0090599 alpha-glucosidase activity;GO:0106407 Glc2Man9GlcNAc2 oligosaccharide glucosidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "GO:0043687 post-translational protein modification;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0005975 carbohydrate metabolic process;GO:0006491 N-glycan processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q94502-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000011000.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q94504-1", "uniprot_id": [ { "id": "CYSP7_DICDI", "url": "https://www.uniprot.org/uniprot/Q94504", "type": "external" } ], "mass": 47166.0, "length": 460, "protein_name": "Cysteine proteinase 7", "gene_name": "cprG", "organism": "Cellular slime mold", "refseq_name": "cysteine proteinase", "refseq_ac": [ { "id": "XP_641720", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641720", "type": "external" } ], "gene_names_uniprotkb": "cprG; CP7; DDB_G0279187", "gene_names_refseq": "cprG", "protein_names_uniprotkb": "Cysteine proteinase 7; 3.4.22.-; Proteinase 1", "protein_names_refseq": "cysteine proteinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279187); (R-DDI-2132295); (R-DDI-5683826); (R-DDI-6798695)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "15875012;9056234", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q54X57", "ec_number_list": [ { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.4.19.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.5.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.-.-", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity;GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0006955 immune response;GO:2001235 positive regulation of apoptotic signaling pathway;GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q94504-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95PI2-1", "uniprot_id": [ { "id": "DHKC_DICDI", "url": "https://www.uniprot.org/uniprot/Q95PI2", "type": "external" } ], "mass": 137347.0, "length": 1225, "protein_name": "Hybrid signal transduction histidine kinase C", "gene_name": "dhkC", "organism": "Cellular slime mold", "refseq_name": "HisK family protein kinase", "refseq_ac": [ { "id": "XP_644273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644273", "type": "external" } ], "gene_names_uniprotkb": "dhkC; DDB_G0274191", "gene_names_refseq": "dhkC", "protein_names_uniprotkb": "Hybrid signal transduction histidine kinase C; 2.7.13.3", "protein_names_refseq": "HisK family protein kinase; histidine kinase; protein kinase, Atypical group", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274191)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12097910;15875012;16188250;16835443;9808785", "class_list": "", "function": "Acts in a signal transduction pathway that regulates the slug versus culmination choice. Believed to be the first component of a phosphorelay that couples the sensing of ammonia to the modulation of PKA activity and hence activates culmination and spore germination. Ammonium transporters amtA and amtC are thought to respectively activate and inhibit dhkC phosphorelay. This protein probably undergoes an ATP-dependent autophosphorylation at conserved His residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15784;Q554Q0", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000155 phosphorelay sensor kinase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0060359 response to ammonium ion;GO:0009847 spore germination;GO:0030587 sorocarp development;GO:0061128 positive regulation of chemotaxis to cAMP by DIF-2;GO:1903831 signal transduction involved in cellular response to ammonium ion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q95PI2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95UQ1-1", "uniprot_id": [ { "id": "GDIR1_DICDI", "url": "https://www.uniprot.org/uniprot/Q95UQ1", "type": "external" } ], "mass": 22340.0, "length": 197, "protein_name": "Putative rho GDP-dissociation inhibitor 1", "gene_name": "rdiA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635396", "type": "external" } ], "gene_names_uniprotkb": "rdiA; DDB_G0291077; RhoGDI1", "gene_names_refseq": "rdiA", "protein_names_uniprotkb": "Putative rho GDP-dissociation inhibitor 1", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291077); (R-DDI-9013149); (R-DDI-9013404); (R-DDI-9013423)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "12163018;12198156;15875012;19010323", "class_list": "", "function": "Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (By similarity). Regulates the Rac-dependent signaling pathways controlling cytokinesis, actin reorganization and the contractile vacuole. Required for efficient accumulation of cap at the cell cortex., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54F58", "ec_number_list": [], "go_molecular_function": "GO:0005094 Rho GDP-dissociation inhibitor activity;GO:0005096 GTPase activator activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0140220 pathogen-containing vacuole", "go_biological_process": "GO:0000902 cell morphogenesis;GO:0009617 response to bacterium;GO:0030036 actin cytoskeleton organization;GO:0007266 Rho protein signal transduction;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q95UQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95YH0-1", "uniprot_id": [ { "id": "CDK8_DICDI", "url": "https://www.uniprot.org/uniprot/Q95YH0", "type": "external" } ], "mass": 42771.0, "length": 380, "protein_name": "Probable cyclin-dependent kinase 8", "gene_name": "cdk8", "organism": "Cellular slime mold", "refseq_name": "CDK family protein kinase", "refseq_ac": [ { "id": "XP_647600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647600", "type": "external" } ], "gene_names_uniprotkb": "cdk8; DDB_G0267442", "gene_names_refseq": "cdk8", "protein_names_uniprotkb": "Probable cyclin-dependent kinase 8; 2.7.11.22; 2.7.11.23; Ddcdk8", "protein_names_refseq": "CDK family protein kinase; CTD kinase; cyclin-dependent kinase; protein kinase, CMGC group; protein serine/threonine kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267442)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12060071;15875012", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity). Involved in cell aggregation, but not growth. Required for starvation-induced expression of genes essential for early development of acaA and/or other genes., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55FD3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006468 protein phosphorylation;GO:0010628 positive regulation of gene expression;GO:0050821 protein stabilization;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95YH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95YL4-1", "uniprot_id": [ { "id": "PEFB_DICDI", "url": "https://www.uniprot.org/uniprot/Q95YL4", "type": "external" } ], "mass": 23307.0, "length": 205, "protein_name": "Penta-EF hand domain-containing protein 2", "gene_name": "pefB", "organism": "Cellular slime mold", "refseq_name": "penta EF hand calcium binding protein", "refseq_ac": [ { "id": "XP_628986", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628986", "type": "external" } ], "gene_names_uniprotkb": "pefB; DDB_G0293530; alg2B", "gene_names_refseq": "pefB", "protein_names_uniprotkb": "Penta-EF hand domain-containing protein 2; Apoptosis-linked gene 2 protein homolog B; Dd-ALG-2b; DdPEF-2", "protein_names_refseq": "penta EF hand calcium binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293530)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11481037;11927596;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54BP3", "ec_number_list": [], "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0030587 sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95YL4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95YL5-1", "uniprot_id": [ { "id": "PEFA_DICDI", "url": "https://www.uniprot.org/uniprot/Q95YL5", "type": "external" } ], "mass": 22355.0, "length": 197, "protein_name": "Penta-EF hand domain-containing protein 1", "gene_name": "pefA", "organism": "Cellular slime mold", "refseq_name": "penta EF hand calcium binding protein", "refseq_ac": [ { "id": "XP_635397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635397", "type": "external" } ], "gene_names_uniprotkb": "pefA; DDB_G0291081; alg2A", "gene_names_refseq": "pefA", "protein_names_uniprotkb": "Penta-EF hand domain-containing protein 1; Apoptosis-linked gene 2 protein homolog A; Dd-ALG-2a; DdPEF-1", "protein_names_refseq": "penta EF hand calcium binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291081)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11481037;11927596;12198156;15875012;16926386", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54F57;Q95UQ0", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0009617 response to bacterium;GO:0009611 response to wounding", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q95YL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95ZG3-1", "uniprot_id": [ { "id": "SPC97_DICDI", "url": "https://www.uniprot.org/uniprot/Q95ZG3", "type": "external" } ], "mass": 154571.0, "length": 1335, "protein_name": "Spindle pole body component 97", "gene_name": "spc97", "organism": "Cellular slime mold", "refseq_name": "spindle pole body component 97", "refseq_ac": [ { "id": "XP_637962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637962", "type": "external" } ], "gene_names_uniprotkb": "spc97; DDB_G0285849", "gene_names_refseq": "spc97", "protein_names_uniprotkb": "Spindle pole body component 97; DdSpc97; Spc97", "protein_names_refseq": "spindle pole body component 97", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285849)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12018385;15875012", "class_list": "", "function": "May be involved in microtubule nucleation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54MM8", "ec_number_list": [], "go_molecular_function": "GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007020 microtubule nucleation;GO:0051225 spindle assembly;GO:0051321 meiotic cell cycle;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95ZG3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95ZG4-1", "uniprot_id": [ { "id": "SPC98_DICDI", "url": "https://www.uniprot.org/uniprot/Q95ZG4", "type": "external" } ], "mass": 94434.0, "length": 813, "protein_name": "Spindle pole body component 98", "gene_name": "spc98", "organism": "Cellular slime mold", "refseq_name": "spindle pole body component 98", "refseq_ac": [ { "id": "XP_638829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638829", "type": "external" } ], "gene_names_uniprotkb": "spc98; DDB_G0283909", "gene_names_refseq": "spc98", "protein_names_uniprotkb": "Spindle pole body component 98; DdSpc98; Spc98", "protein_names_refseq": "spindle pole body component 98", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283909)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12018385;15875012;16512674", "class_list": "", "function": "May be involved in microtubule nucleation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54QB5", "ec_number_list": [], "go_molecular_function": "GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007020 microtubule nucleation;GO:0051225 spindle assembly;GO:0051321 meiotic cell cycle;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95ZG4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95ZG8-1", "uniprot_id": [ { "id": "GBG_DICDI", "url": "https://www.uniprot.org/uniprot/Q95ZG8", "type": "external" } ], "mass": 7679.0, "length": 69, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "gpgA", "organism": "Cellular slime mold", "refseq_name": "G-protein subunit gamma", "refseq_ac": [ { "id": "XP_644080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644080", "type": "external" } ], "gene_names_uniprotkb": "gpgA; DDB_G0274125; gg", "gene_names_refseq": "gpgA", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "G-protein subunit gamma", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274125)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11598203;12097910;14517243;15875012;16135826", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. This major G protein of the squid photoreceptor is involved in visual transduction. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). Required for normal chemotaxis in response to cAMP., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q556F4", "ec_number_list": [], "go_molecular_function": "GO:0031681 G-protein beta-subunit binding;GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0031152 aggregation involved in sorocarp development;GO:0043327 chemotaxis to cAMP", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q95ZG8-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q964D8-1", "uniprot_id": [ { "id": "BUP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q964D8", "type": "external" } ], "mass": 44089.0, "length": 391, "protein_name": "Beta-ureidopropionase", "gene_name": "pyd3", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_644181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644181", "type": "external" } ], "gene_names_uniprotkb": "pyd3; DDB_G0274123; bup1; upb1", "gene_names_refseq": "pyd3", "protein_names_uniprotkb": "Beta-ureidopropionase; 3.5.1.6; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolase", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274123); (R-DDI-73621)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "11454750;12097910;15875012", "class_list": "", "function": "Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide (PubMed:11454750). Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q554Z2", "ec_number_list": [ { "id": "3.5.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.6", "type": "external" } ], "go_molecular_function": "GO:0003837 beta-ureidopropionase activity", "go_cellular_component": "GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0033396 beta-alanine biosynthetic process via 3-ureidopropionate", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q964D8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q966U0-1", "uniprot_id": [ { "id": "END4_DICDI", "url": "https://www.uniprot.org/uniprot/Q966U0", "type": "external" } ], "mass": 61952.0, "length": 542, "protein_name": "Endonuclease 4 homolog", "gene_name": "apnA", "organism": "Cellular slime mold", "refseq_name": "apurinic/apyrimidinic endonuclease", "refseq_ac": [ { "id": "XP_641436", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641436", "type": "external" } ], "gene_names_uniprotkb": "apnA; DDB_G0279923", "gene_names_refseq": "apnA", "protein_names_uniprotkb": "Endonuclease 4 homolog; 3.1.21.2; AP endonuclease; Apurinic/apyrimidinic endonuclease; DdAPN; Endodeoxyribonuclease IV homolog; Endonuclease IV homolog", "protein_names_refseq": "apurinic/apyrimidinic endonuclease; endonuclease IV", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0279923)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11356336;15875012", "class_list": "", "function": "Plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54W14", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008081 phosphoric diester hydrolase activity;GO:0008833 deoxyribonuclease IV (phage-T4-induced) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q966U0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q967U1-1", "uniprot_id": [ { "id": "PSME_DICDI", "url": "https://www.uniprot.org/uniprot/Q967U1", "type": "external" } ], "mass": 26226.0, "length": 225, "protein_name": "Proteasome activator 28", "gene_name": "psmE3", "organism": "Cellular slime mold", "refseq_name": "proteasome activator 28 subunit", "refseq_ac": [ { "id": "XP_639877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639877", "type": "external" } ], "gene_names_uniprotkb": "psmE3; DDB_G0285099; dpr1", "gene_names_refseq": "psmE3", "protein_names_uniprotkb": "Proteasome activator 28; PA28 homolog", "protein_names_refseq": "proteasome activator 28 subunit; proteasome activator complex subunit 3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285099); (R-DDI-1236974); (R-DDI-1236978); (R-DDI-9907900); (R-DDI-9912633)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15875012;19411624", "class_list": "", "function": "Subunit of the 11S REG (also called PA28) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates preferentially the trypsin-like catalytic subunit of the proteasome. May also be involved in cell cycle regulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54NN9", "ec_number_list": [], "go_molecular_function": "GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0032991 protein-containing complex;GO:0008537 proteasome activator complex", "go_biological_process": "GO:0030163 protein catabolic process;GO:2000045 regulation of G1/S transition of mitotic cell cycle;GO:0061136 regulation of proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q967U1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q968Z6-1", "uniprot_id": [ { "id": "PSIA_DICDI", "url": "https://www.uniprot.org/uniprot/Q968Z6", "type": "external" } ], "mass": 62300.0, "length": 557, "protein_name": "Protein psiA", "gene_name": "psiA", "organism": "Cellular slime mold", "refseq_name": "PA14 domain-containing protein", "refseq_ac": [ { "id": "XP_629768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629768", "type": "external" } ], "gene_names_uniprotkb": "psiA; DDB_G0291982", "gene_names_refseq": "psiA", "protein_names_uniprotkb": "Protein psiA; Prespore-cell-inducing factor A", "protein_names_refseq": "PA14 domain-containing protein; prespore-cell-inducing factor; psi factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291982)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10493938;15367206;15875012", "class_list": "", "function": "Growth factor that can induce isolated amoebae to differentiate into prespore cells., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 11, "predicted_n_glycosites": 6, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "Q54DV4", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0030154 cell differentiation;GO:1901263 positive regulation of sorocarp spore cell differentiation;GO:0031286 negative regulation of sorocarp stalk cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q968Z6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BIW4-1", "uniprot_id": [ { "id": "LIMD_DICDI", "url": "https://www.uniprot.org/uniprot/Q9BIW4", "type": "external" } ], "mass": 21501.0, "length": 198, "protein_name": "LIM domain-containing protein D", "gene_name": "limD", "organism": "Cellular slime mold", "refseq_name": "LIM-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_637163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637163", "type": "external" } ], "gene_names_uniprotkb": "limD; DDB_G0287507; limD1", "gene_names_refseq": "limD1", "protein_names_uniprotkb": "LIM domain-containing protein D", "protein_names_refseq": "LIM-type zinc finger-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287507); (R-DDI-983231)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12374734;15875012", "class_list": "", "function": "Binds to F-actin and may modulate the chemotactic response during early development and contribute to the maintenance of the strength of the actin cytoskeleton., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54K92", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0031143 pseudopodium", "go_biological_process": "GO:0006970 response to osmotic stress;GO:0007015 actin filament organization;GO:0051017 actin filament bundle assembly;GO:0030866 cortical actin cytoskeleton organization;GO:0030010 establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BIW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BIW5-1", "uniprot_id": [ { "id": "LIMC_DICDI", "url": "https://www.uniprot.org/uniprot/Q9BIW5", "type": "external" } ], "mass": 20555.0, "length": 182, "protein_name": "LIM domain-containing protein C", "gene_name": "limC", "organism": "Cellular slime mold", "refseq_name": "LIM-type zinc finger-containing protein", "refseq_ac": [ { "id": "XP_642140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642140", "type": "external" } ], "gene_names_uniprotkb": "limC; DDB_G0277881", "gene_names_refseq": "limC", "protein_names_uniprotkb": "LIM domain-containing protein C", "protein_names_refseq": "LIM-type zinc finger-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277881)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12374734;15875012", "class_list": "", "function": "Binds to F-actin and may modulate the chemotactic response during early development and contribute to the maintenance of the strength of the actin cytoskeleton., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54YR2", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005938 cell cortex;GO:0031143 pseudopodium;GO:0044354 macropinosome;GO:0031941 filamentous actin", "go_biological_process": "GO:0006935 chemotaxis;GO:0006970 response to osmotic stress;GO:0030866 cortical actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BIW5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BKJ9-1", "uniprot_id": [ { "id": "LMPB_DICDI", "url": "https://www.uniprot.org/uniprot/Q9BKJ9", "type": "external" } ], "mass": 82572.0, "length": 755, "protein_name": "Lysosome membrane protein 2-B", "gene_name": "lmpB", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_637399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637399", "type": "external" } ], "gene_names_uniprotkb": "lmpB; DDB_G0287035", "gene_names_refseq": "lmpB", "protein_names_uniprotkb": "Lysosome membrane protein 2-B; LIMP II-2; Lysosome membrane protein II-2", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287035); (R-DDI-114608); (R-DDI-434313); (R-DDI-6798695)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "11489884;15875012", "class_list": "", "function": "May act as a lysosomal receptor (By similarity). May be involved in macropinocytosis and fluid phase exocytosis., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q54KX1", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0031982 vesicle;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006911 phagocytosis, engulfment", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BKJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BLG3-1", "uniprot_id": [ { "id": "AMT2_DICDI", "url": "https://www.uniprot.org/uniprot/Q9BLG3", "type": "external" } ], "mass": 46368.0, "length": 431, "protein_name": "Ammonium transporter 2", "gene_name": "amtB", "organism": "Cellular slime mold", "refseq_name": "ammonium transporter", "refseq_ac": [ { "id": "XP_642123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642123", "type": "external" } ], "gene_names_uniprotkb": "amtB; DDB_G0277889", "gene_names_refseq": "amtB", "protein_names_uniprotkb": "Ammonium transporter 2", "protein_names_refseq": "ammonium transporter", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277889)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14686953;15875012;17951519;19108721", "class_list": "", "function": "Ammonium transporter that mediates the excretion of ammonium from the prestalk cells from the slug. Controls ammonium homeostasis during growth and development. Ammonium has been shown to function as a morphogen at multiple steps during the development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54YS9", "ec_number_list": [], "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0036020 endolysosome membrane;GO:0031164 contractile vacuolar membrane", "go_biological_process": "GO:0097272 ammonium homeostasis;GO:0072488 ammonium transmembrane transport;GO:0046903 secretion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9BLG3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BLG4-1", "uniprot_id": [ { "id": "AMT1_DICDI", "url": "https://www.uniprot.org/uniprot/Q9BLG4", "type": "external" } ], "mass": 49051.0, "length": 463, "protein_name": "Ammonium transporter 1", "gene_name": "amtA", "organism": "Cellular slime mold", "refseq_name": "ammonium transporter", "refseq_ac": [ { "id": "XP_642645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642645", "type": "external" } ], "gene_names_uniprotkb": "amtA; DDB_G0277503", "gene_names_refseq": "amtA", "protein_names_uniprotkb": "Ammonium transporter 1", "protein_names_refseq": "ammonium transporter", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277503)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12097910;14686953;15875012;16835443;17951519;19108721", "class_list": "", "function": "Ammonium transporter that mediates the excretion of ammonium. Controls ammonium homeostasis during growth and development. Ammonium has been shown to function as a morphogen at multiple steps during the development., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54ZJ7", "ec_number_list": [], "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005886 plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0005774 vacuolar membrane;GO:0036020 endolysosome membrane", "go_biological_process": "GO:0097275 intracellular ammonium homeostasis;GO:0072488 ammonium transmembrane transport;GO:0046903 secretion;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0019954 asexual reproduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9BLG4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BPU3-1", "uniprot_id": [ { "id": "KIF2_DICDI", "url": "https://www.uniprot.org/uniprot/Q9BPU3", "type": "external" } ], "mass": 89360.0, "length": 792, "protein_name": "Kinesin-related protein 2", "gene_name": "kif2", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 2", "refseq_ac": [ { "id": "XP_647135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647135", "type": "external" } ], "gene_names_uniprotkb": "kif2; DDB_G0267396; GPK2; K2; ksnB", "gene_names_refseq": "kif2", "protein_names_uniprotkb": "Kinesin-related protein 2; Kinesin family member 2; Kinesin-14", "protein_names_refseq": "kinesin family member 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267396)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10854856;14641909;15875012;9693369", "class_list": "", "function": "Microtubule-dependent motor that is probably involved in microtubule organization in the mitotic spindle., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O15718;Q55GP9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0090307 mitotic spindle assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9BPU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GPF1-1", "uniprot_id": [ { "id": "AP3M_DICDI", "url": "https://www.uniprot.org/uniprot/Q9GPF1", "type": "external" } ], "mass": 47144.0, "length": 421, "protein_name": "AP-3 complex subunit mu", "gene_name": "apm3", "organism": "Cellular slime mold", "refseq_name": "clathrin-adaptor medium chain AP-3", "refseq_ac": [ { "id": "XP_642328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642328", "type": "external" } ], "gene_names_uniprotkb": "apm3; DDB_G0277901", "gene_names_refseq": "apm3", "protein_names_uniprotkb": "AP-3 complex subunit mu; AP-3 adaptor complex mu3 subunit; Adaptor-related protein complex 3 subunit mu; Clathrin-adaptor medium chain Apm3; Mu3-adaptin", "protein_names_refseq": "clathrin-adaptor medium chain AP-3", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277901)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11179674;15875012;17010123", "class_list": "", "function": "Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q54Y74", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0010008 endosome membrane;GO:0005802 trans-Golgi network;GO:0030123 AP-3 adaptor complex;GO:0030121 AP-1 adaptor complex;GO:0031201 SNARE complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0007032 endosome organization;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GPF1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GPM4-1", "uniprot_id": [ { "id": "PGK_DICDI", "url": "https://www.uniprot.org/uniprot/Q9GPM4", "type": "external" } ], "mass": 45709.0, "length": 420, "protein_name": "Phosphoglycerate kinase", "gene_name": "pgkA", "organism": "Cellular slime mold", "refseq_name": "calmodulin-binding protein", "refseq_ac": [ { "id": "XP_637130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637130", "type": "external" } ], "gene_names_uniprotkb": "pgkA; DDB_G0287595", "gene_names_refseq": "pgkA", "protein_names_uniprotkb": "Phosphoglycerate kinase; 2.7.2.3", "protein_names_refseq": "calmodulin-binding protein; phosphoglycerate kinase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0287595); (R-DDI-70171); (R-DDI-70263)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "11923193;12912885;15363631;15875012;16926386", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54K34", "ec_number_list": [ { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" } ], "go_molecular_function": "GO:0004618 phosphoglycerate kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043531 ADP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0045121 membrane raft;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9GPM4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GPQ8-1", "uniprot_id": [ { "id": "RACL_DICDI", "url": "https://www.uniprot.org/uniprot/Q9GPQ8", "type": "external" } ], "mass": 22368.0, "length": 196, "protein_name": "Rho-related protein racL", "gene_name": "racL", "organism": "Cellular slime mold", "refseq_name": "Rho GTPase", "refseq_ac": [ { "id": "XP_629400", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629400", "type": "external" } ], "gene_names_uniprotkb": "racL; DDB_G0292816", "gene_names_refseq": "racL", "protein_names_uniprotkb": "Rho-related protein racL; 3.6.5.2", "protein_names_refseq": "Rho GTPase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292816); (R-DDI-9013423)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "11222756;15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54CL6", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0042995 cell projection", "go_biological_process": "GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9GPQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GPR7-1", "uniprot_id": [ { "id": "RACH_DICDI", "url": "https://www.uniprot.org/uniprot/Q9GPR7", "type": "external" } ], "mass": 22189.0, "length": 200, "protein_name": "Rho-related protein racH", "gene_name": "racH", "organism": "Cellular slime mold", "refseq_name": "Rho GTPase", "refseq_ac": [ { "id": "XP_646202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646202", "type": "external" } ], "gene_names_uniprotkb": "racH; 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DDB_G0288247", "gene_names_refseq": "aif", "protein_names_uniprotkb": "Apoptosis-inducing factor 1, mitochondrial; 1.6.99.-; Ddaif", "protein_names_refseq": "apoptosis inducing factor", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0288247)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11598188;15875012", "class_list": "", "function": "Probable NADH oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54J72", "ec_number_list": [ { "id": "1.6.99.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.99.1", "type": "external" }, { "id": "1.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0003954 NADH dehydrogenase activity;GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0071949 FAD binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0045335 phagocytic vesicle;GO:0140220 pathogen-containing vacuole", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0033108 mitochondrial respiratory chain complex assembly;GO:0051881 regulation of mitochondrial membrane potential;GO:0072593 reactive oxygen species metabolic process;GO:0030261 chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9GRX6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GSG9-1", "uniprot_id": [ { "id": "Q9GSG9_DICDI", "url": "https://www.uniprot.org/uniprot/Q9GSG9", "type": "external" } ], "mass": 42446.0, "length": 399, "protein_name": "Wiscott-Aldrich syndrome protein", "gene_name": "wasA", "organism": "Cellular slime mold", "refseq_name": "Wiscott-Aldrich syndrome protein", "refseq_ac": [ { "id": "XP_628937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628937", "type": "external" } ], "gene_names_uniprotkb": "wasA; DDB_G0293834", "gene_names_refseq": "wasA", "protein_names_uniprotkb": "Wiscott-Aldrich syndrome protein", "protein_names_refseq": "Wiscott-Aldrich syndrome protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293834)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54B83", "ec_number_list": [], "go_molecular_function": "GO:0003785 actin monomer binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005905 clathrin-coated pit;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0032060 bleb assembly;GO:0030838 positive regulation of actin filament polymerization;GO:0030950 establishment or maintenance of actin cytoskeleton polarity;GO:0031269 pseudopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9GSG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GTN7-1", "uniprot_id": [ { "id": "TAGA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9GTN7", "type": "external" } ], "mass": 192812.0, "length": 1752, "protein_name": "Serine protease/ABC transporter B family protein tagA", "gene_name": "tagA", "organism": "Cellular slime mold", "refseq_name": "ABC transporter B family protein", "refseq_ac": [ { "id": "XP_629328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629328", "type": "external" } ], "gene_names_uniprotkb": "tagA; DDB_G0293002", "gene_names_refseq": "tagA", "protein_names_uniprotkb": "Serine protease/ABC transporter B family protein tagA; 3.4.21.-", "protein_names_refseq": "ABC transporter B family protein; serine protease", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0293002); (R-DDI-159418); (R-DDI-193368); (R-DDI-382556); (R-DDI-9754706); (R-DDI-9757110); (R-DDI-983170)", "pathway_count": 7, "publication_count": 4, "publication_id_list": "12756178;15875012;17056744;18559084", "class_list": "", "function": "Required for a general cell fate determination at the onset of development. Required for the specification of an initial population of prespore cells in which tagA is expressed. Required for normal SDF-2 signaling during spore encapsulation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 11, "predicted_n_glycosites": 10, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "Q54C91", "ec_number_list": [ { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0030154 cell differentiation;GO:0055085 transmembrane transport;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9GTN7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NA13-1", "uniprot_id": [ { "id": "IPLA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NA13", "type": "external" } ], "mass": 360531.0, "length": 3177, "protein_name": "Inositol 1,4,5-trisphosphate receptor-like protein A", "gene_name": "iplA", "organism": "Cellular slime mold", "refseq_name": "Ca2+ channel", "refseq_ac": [ { "id": "XP_629509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629509", "type": "external" } ], "gene_names_uniprotkb": "iplA; DDB_G0292564", "gene_names_refseq": "iplA", "protein_names_uniprotkb": "Inositol 1,4,5-trisphosphate receptor-like protein A", "protein_names_refseq": "Ca2+ channel; inositol 1,4,5-trisphosphate receptor-like protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292564); (R-DDI-114508); (R-DDI-139853); (R-DDI-381676); (R-DDI-5578775); (R-DDI-9717207)", "pathway_count": 6, "publication_count": 12, "publication_id_list": "10970875;12211100;15760480;15875012;17077123;17854889;18077554;18196962;18359017;18486207;19133302;35859163", "class_list": "", "function": "May be a receptor for inositol 1,4,5-trisphosphate which governs calcium fluxes from the endoplasmic reticulum stores into the cytosol. May be involved in autophagic cell death. Partially responsible for intracellular Ca(2+) bursts from internal stores in response to mechanical stimuli in slugs (PubMed:18359017, PubMed:35859163)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 28, "predicted_n_glycosites": 28, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 28, "binding_glycan_count": 0, "secondary_ac_list": "Q54D11", "ec_number_list": [], "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0005220 inositol 1,4,5-trisphosphate-gated calcium channel activity;GO:0005509 calcium ion binding;GO:0015085 calcium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0097231 cell motility in response to calcium ion;GO:0006935 chemotaxis;GO:0006816 calcium ion transport;GO:0051209 release of sequestered calcium ion into cytosol;GO:0071260 cellular response to mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9NA13-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NAX4-1", "uniprot_id": [ { "id": "SP65_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NAX4", "type": "external" } ], "mass": 47250.0, "length": 464, "protein_name": "Spore coat protein SP65", "gene_name": "cotE", "organism": "Cellular slime mold", "refseq_name": "spore coat protein", "refseq_ac": [ { "id": "XP_642186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642186", "type": "external" } ], "gene_names_uniprotkb": "cotE; DDB_G0277903; SP65", "gene_names_refseq": "cotE", "protein_names_uniprotkb": "Spore coat protein SP65; Spore coat protein E", "protein_names_refseq": "spore coat protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277903)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10564654;15875012;17416892", "class_list": "", "function": "Forms a triad with cellulose and pspB that is essential for spore outer layer formation., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q54YL6", "ec_number_list": [], "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0031160 spore wall", "go_biological_process": "GO:0030435 sporulation resulting in formation of a cellular spore;GO:0042244 spore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9NAX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NCL8-1", "uniprot_id": [ { "id": "PITP1_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NCL8", "type": "external" } ], "mass": 31157.0, "length": 264, "protein_name": "Phosphatidylinositol transfer protein 1", "gene_name": "pitA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635910", "type": "external" } ], "gene_names_uniprotkb": "pitA; DDB_G0290069", "gene_names_refseq": "pitA", "protein_names_uniprotkb": "Phosphatidylinositol transfer protein 1; DdPITP1; PtdIns transfer protein 1", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290069); (R-DDI-1483196)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10769190;15352238;15875012", "class_list": "", "function": "Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54GK7", "ec_number_list": [], "go_molecular_function": "GO:0031210 phosphatidylcholine binding;GO:0035091 phosphatidylinositol binding;GO:0008526 phosphatidylinositol transfer activity;GO:0008525 phosphatidylcholine transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0071944 cell periphery", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9NCL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NGP5-1", "uniprot_id": [ { "id": "ABCG2_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NGP5", "type": "external" } ], "mass": 149123.0, "length": 1328, "protein_name": "ABC transporter G family member 2", "gene_name": "abcG2", "organism": "Cellular slime mold", "refseq_name": "ABC transporter G family protein", "refseq_ac": [ { "id": "XP_643503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643503", "type": "external" } ], "gene_names_uniprotkb": "abcG2; DDB_G0275689; mdra1", "gene_names_refseq": "abcG2", "protein_names_uniprotkb": "ABC transporter G family member 2; ABC transporter ABCG.2", "protein_names_refseq": "ABC transporter G family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0275689)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11719559;12097910;12456012;15875012", "class_list": "", "function": "Required for endocytosis and endosomal pH regulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q553B7;Q8MXM4", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0016020 membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0030154 cell differentiation;GO:0048388 endosomal lumen acidification;GO:0031152 aggregation involved in sorocarp development;GO:0031288 sorocarp morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9NGP5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NGQ2-1", "uniprot_id": [ { "id": "KIF1_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NGQ2", "type": "external" } ], "mass": 248003.0, "length": 2205, "protein_name": "Kinesin-related protein 1", "gene_name": "kif1", "organism": "Cellular slime mold", "refseq_name": "kinesin family member 1", "refseq_ac": [ { "id": "XP_635456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635456", "type": "external" } ], "gene_names_uniprotkb": "kif1; DDB_G0290963; kif1A; unc104", "gene_names_refseq": "kif1", "protein_names_uniprotkb": "Kinesin-related protein 1; Kinesin family member 1; Kinesin-3", "protein_names_refseq": "kinesin family member 1", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290963)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10545495;12015984;14641909;15875012", "class_list": "", "function": "Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. Transports cytoplasmic vesicles and particularly phosphatidylinositol 4,5-bisphosphate-containing liposomes along microtubules., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54F81", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0047496 vesicle transport along microtubule;GO:0072383 plus-end-directed vesicle transport along microtubule;GO:0072386 plus-end-directed organelle transport along microtubule", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9NGQ2-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NH03-1", "uniprot_id": [ { "id": "FPS_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NH03", "type": "external" } ], "mass": 43590.0, "length": 382, "protein_name": "Farnesyl diphosphate synthase", "gene_name": "fps", "organism": "Cellular slime mold", "refseq_name": "FDP synthase", "refseq_ac": [ { "id": "XP_641990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641990", "type": "external" } ], "gene_names_uniprotkb": "fps; DDB_G0278735", "gene_names_refseq": "fps", "protein_names_uniprotkb": "Farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.10; 2.5.1.1; Dfps; Dimethylallyltranstransferase; Geranyltranstransferase", "protein_names_refseq": "FDP synthase; farnesyl diphosphate synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0278735); (R-DDI-9969896)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10804029;12086477;15875012", "class_list": "", "function": "Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a sterol precursor. Involved in the inhibition of cell growth., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54XP0", "ec_number_list": [ { "id": "2.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.1", "type": "external" }, { "id": "2.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.10", "type": "external" }, { "id": "2.5.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.29", "type": "external" }, { "id": "2.5.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.-", "type": "external" } ], "go_molecular_function": "GO:0004161 dimethylallyltranstransferase activity;GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome", "go_biological_process": "GO:0033384 geranyl diphosphate biosynthetic process;GO:0045337 farnesyl diphosphate biosynthetic process;GO:0006695 cholesterol biosynthetic process;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9NH03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NI62-1", "uniprot_id": [ { "id": "CYPE_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NI62", "type": "external" } ], "mass": 17415.0, "length": 156, "protein_name": "Peptidyl-prolyl cis-trans isomerase cypE", "gene_name": "cypE", "organism": "Cellular slime mold", "refseq_name": "cyclophilin-type peptidylprolyl cis-trans isomerase", "refseq_ac": [ { "id": "XP_646239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646239", "type": "external" } ], "gene_names_uniprotkb": "cypE; DDB_G0269216", "gene_names_refseq": "cypE", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase cypE; 5.2.1.8; Cyclophilin cypE; PPIase cypE; Rotamase cypE", "protein_names_refseq": "cyclophilin-type peptidylprolyl cis-trans isomerase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269216); (R-DDI-72163)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "11690648;15875012", "class_list": "", "function": "Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:11690648). Plays a role in protein folding, transport and assembly (PubMed:11690648)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q55D92", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" } ], "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0006457 protein folding;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9NI62-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NIV0-1", "uniprot_id": [ { "id": "RHGA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NIV0", "type": "external" } ], "mass": 58360.0, "length": 527, "protein_name": "Rhesus-like glycoprotein A", "gene_name": "rhgA", "organism": "Cellular slime mold", "refseq_name": "Rh-like protein/ammonium transporter", "refseq_ac": [ { "id": "XP_639042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639042", "type": "external" } ], "gene_names_uniprotkb": "rhgA; DDB_G0283389", "gene_names_refseq": "rhgA", "protein_names_uniprotkb": "Rhesus-like glycoprotein A; Rh50-like protein rhgA", "protein_names_refseq": "Rh-like protein/ammonium transporter; Rhesus-like glycoprotein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0283389); (R-DDI-1237044); (R-DDI-1247673); (R-DDI-444411)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10852913;11220631;15875012;16478785;17659086", "class_list": "", "function": "May be a carbon dioxide/bicarbonate transporter., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54R49", "ec_number_list": [], "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0000331 contractile vacuole", "go_biological_process": "GO:0097272 ammonium homeostasis;GO:0072488 ammonium transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9NIV0-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NKW1-1", "uniprot_id": [ { "id": "MFEA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NKW1", "type": "external" } ], "mass": 46387.0, "length": 441, "protein_name": "Peroxisomal multifunctional enzyme A", "gene_name": "mfeA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_635235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635235", "type": "external" } ], "gene_names_uniprotkb": "mfeA; DDB_G0291247; mfe1", "gene_names_refseq": "mfeA", "protein_names_uniprotkb": "Peroxisomal multifunctional enzyme A; MFE-1; MFE-A", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0291247)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12796309;15875012", "class_list": "", "function": "Enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Protects the cells from the increase of the harmful xenobiotic fatty acids incorporated from their diets and optimizes cellular lipid composition for proper development., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54EK5", "ec_number_list": [ { "id": "1.1.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.35", "type": "external" } ], "go_molecular_function": "GO:0004300 enoyl-CoA hydratase activity;GO:0003857 (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0030587 sorocarp development;GO:0140582 adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9NKW1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9NKX1-1", "uniprot_id": [ { "id": "ENPL_DICDI", "url": "https://www.uniprot.org/uniprot/Q9NKX1", "type": "external" } ], "mass": 87269.0, "length": 768, "protein_name": "Endoplasmin homolog", "gene_name": "grp94", "organism": "Cellular slime mold", "refseq_name": "heat shock protein Hsp90 family protein", "refseq_ac": [ { "id": "XP_641313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641313", "type": "external" } ], "gene_names_uniprotkb": "grp94; DDB_G0280057", "gene_names_refseq": "grp94", "protein_names_uniprotkb": "Endoplasmin homolog; 92 kDa phosphoprotein; GRP-94 homolog; Glucose-regulated protein 94 homolog", "protein_names_refseq": "heat shock protein Hsp90 family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280057); (R-DDI-6785807)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10913338;15652353;15875012", "class_list": "", "function": "May play a role in late differentiation as well as in starvation response. When overexpressed, suppresses the ability to form normal fruiting bodies and impairs prespore differentiation as well as maturation into spores., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q54VP2", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005798 Golgi-associated vesicle;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006457 protein folding;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9NKX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TW28-1", "uniprot_id": [ { "id": "MYOM_DICDI", "url": "https://www.uniprot.org/uniprot/Q9TW28", "type": "external" } ], "mass": 195862.0, "length": 1737, "protein_name": "Myosin-M heavy chain", "gene_name": "myoM", "organism": "Cellular slime mold", "refseq_name": "Rac guanyl-nucleotide exchange factor", "refseq_ac": [ { "id": "XP_629701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629701", "type": "external" } ], "gene_names_uniprotkb": "myoM; DDB_G0292262; racGEF", "gene_names_refseq": "myoM", "protein_names_uniprotkb": "Myosin-M heavy chain; RhoGEF domain-containing protein myoM", "protein_names_refseq": "Rac guanyl-nucleotide exchange factor; RhoGEF domain-containing protein; calmodulin-binding protein; unconventional myosin heavy chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292262); (R-DDI-9013418); (R-DDI-9013422)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10403059;10828443;11208126;15875012;16857047", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity. Involved in macropinocytosis and remodeling of actin cytoskeleton., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q54DE0", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0016020 membrane;GO:0042995 cell projection;GO:0016459 myosin complex", "go_biological_process": "GO:0031268 pseudopodium organization;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0035020 regulation of Rac protein signal transduction;GO:0006972 hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9TW28-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TW32-1", "uniprot_id": [ { "id": "PPIB_DICDI", "url": "https://www.uniprot.org/uniprot/Q9TW32", "type": "external" } ], "mass": 21399.0, "length": 197, "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "cypB", "organism": "Cellular slime mold", "refseq_name": "cyclophilin B", "refseq_ac": [ { "id": "XP_646208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646208", "type": "external" } ], "gene_names_uniprotkb": "cypB; DDB_G0269120; cyp2", "gene_names_refseq": "cypB", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase B; 5.2.1.8; Cyclophilin B; PPIase B; Rotamase B", "protein_names_refseq": "cyclophilin B", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269120); (R-DDI-6781823); (R-DDI-6782135); (R-DDI-6782210); (R-DDI-6798695); (R-DDI-72163)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "10575348;15875012", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q55DC3", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.4.23.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.3.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "2.4.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.25", "type": "external" }, { "id": "3.2.1.33", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.33", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.4.18.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.18.1", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.8", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.4.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.1", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "1.11.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.2.-", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "3.4.19.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.-", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043231 intracellular membrane-bounded organelle", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TW32-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TX43-1", "uniprot_id": [ { "id": "CAR4_DICDI", "url": "https://www.uniprot.org/uniprot/Q9TX43", "type": "external" } ], "mass": 51467.0, "length": 443, "protein_name": "Cyclic AMP receptor 4", "gene_name": "carD", "organism": "Cellular slime mold", "refseq_name": "G-protein-coupled receptor", "refseq_ac": [ { "id": "XP_642216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642216", "type": "external" } ], "gene_names_uniprotkb": "carD; DDB_G0277831; car4", "gene_names_refseq": "carD", "protein_names_uniprotkb": "Cyclic AMP receptor 4; cAMP receptor 4", "protein_names_refseq": "G-protein-coupled receptor; cAMP receptor 4", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277831)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;7958880", "class_list": "", "function": "Receptor for cAMP. Regulates axial patterning and cellular differentiation during late development. The activity of this receptor is mediated by G proteins., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q54YI6", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008160 protein tyrosine phosphatase activator activity;GO:0030552 cAMP binding;GO:0001646 cAMP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TX43-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U1M8-1", "uniprot_id": [ { "id": "MYOI_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U1M8", "type": "external" } ], "mass": 268284.0, "length": 2357, "protein_name": "Myosin-I heavy chain", "gene_name": "myoI", "organism": "Cellular slime mold", "refseq_name": "class VII unconventional myosin", "refseq_ac": [ { "id": "XP_644171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_644171", "type": "external" } ], "gene_names_uniprotkb": "myoI; DDB_G0274455", "gene_names_refseq": "myoI", "protein_names_uniprotkb": "Myosin-I heavy chain; Class VII unconventional myosin; DdM7; DdMVII", "protein_names_refseq": "class VII unconventional myosin; myosin VII", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274455); (R-DDI-9013418); (R-DDI-9013422)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "10574761;11267868;12097910;15826949;15875012;16857047;17189480;17671169", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity. Involved in the early steps of phagocytosis and adhesion., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "P90536;Q555A2;Q869S1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0046847 filopodium assembly;GO:0051592 response to calcium ion;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9U1M8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U1M9-1", "uniprot_id": [ { "id": "DYNB_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U1M9", "type": "external" } ], "mass": 105254.0, "length": 920, "protein_name": "Dynamin-B", "gene_name": "dymB", "organism": "Cellular slime mold", "refseq_name": "dynamin B", "refseq_ac": [ { "id": "XP_642447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642447", "type": "external" } ], "gene_names_uniprotkb": "dymB; DDB_G0277851", "gene_names_refseq": "dymB", "protein_names_uniprotkb": "Dynamin-B", "protein_names_refseq": "dynamin B", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0277851); (R-DDI-169911)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Enzyme hydrolyzing GTP., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54XV5", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0016559 peroxisome fission;GO:0006909 phagocytosis;GO:0009617 response to bacterium;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9U1M9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U3X4-1", "uniprot_id": [ { "id": "SDHA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U3X4", "type": "external" } ], "mass": 68516.0, "length": 626, "protein_name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "gene_name": "sdhA", "organism": "Cellular slime mold", "refseq_name": "complex II, flavoprotein subunit", "refseq_ac": [ { "id": "XP_641069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641069", "type": "external" } ], "gene_names_uniprotkb": "sdhA; DDB_G0280535", "gene_names_refseq": "sdhA", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; 1.3.5.1; FP; Flavoprotein subunit of complex II", "protein_names_refseq": "complex II, flavoprotein subunit; succinate dehydrogenase; succinic dehydrogenase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280535); (R-DDI-71403); (R-DDI-9854311)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54V62", "ec_number_list": [ { "id": "1.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.5.1", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008177 succinate dehydrogenase (quinone) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045335 phagocytic vesicle;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0050829 defense response to Gram-negative bacterium;GO:0006909 phagocytosis;GO:0007005 mitochondrion organization;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9U3X4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U720-1", "uniprot_id": [ { "id": "DCSA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U720", "type": "external" } ], "mass": 121412.0, "length": 1059, "protein_name": "Cellulose synthase catalytic subunit A [UDP-forming]", "gene_name": "dcsA", "organism": "Cellular slime mold", "refseq_name": "UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase", "refseq_ac": [ { "id": "XP_646256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646256", "type": "external" } ], "gene_names_uniprotkb": "dcsA; DDB_G0269124", "gene_names_refseq": "dcsA", "protein_names_uniprotkb": "Cellulose synthase catalytic subunit A [UDP-forming]; 2.4.1.12; DcsA", "protein_names_refseq": "UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase; cellulose synthase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269124)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10681463;15875012", "class_list": "glycogene;glycosyltransferase", "function": "Catalytic subunit of cellulose synthase. It incorporates glucose from uridine 5'-diphosphate glucose (UDP-alpha-D-glucose) to cellulose (a (1->4)-beta-D-glucan), which is produced as an extracellular component for mechanical and chemical protection at the onset of the stalk formation, when the cells exhibit multicellular behavior during culmination., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55D75", "ec_number_list": [ { "id": "2.4.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.12", "type": "external" } ], "go_molecular_function": "GO:0016758 hexosyltransferase activity;GO:0016760 cellulose synthase (UDP-forming) activity", "go_cellular_component": "GO:0045179 apical cortex;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0030244 cellulose biosynthetic process;GO:0031150 sorocarp stalk development;GO:0042244 spore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9U720-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U7C9-1", "uniprot_id": [ { "id": "NUCMR_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U7C9", "type": "external" } ], "mass": 85404.0, "length": 756, "protein_name": "Nucleomorphin", "gene_name": "numA", "organism": "Cellular slime mold", "refseq_name": "calmodulin-binding protein", "refseq_ac": [ { "id": "XP_001134480", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001134480", "type": "external" } ], "gene_names_uniprotkb": "numA; DDB_G0269114; cmbA; numB", "gene_names_refseq": "numA", "protein_names_uniprotkb": "Nucleomorphin; Calmodulin-binding protein A; Calmodulin-binding protein CaM-BP38", "protein_names_refseq": "calmodulin-binding protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269114)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11919178;11923193;12912885;15325281;15535983;15875012;15896312", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C7FZX6;Q55BM2;Q55BM3;Q6GW01", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005813 centrosome", "go_biological_process": "GO:0007088 regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9U7C9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U8P7-1", "uniprot_id": [ { "id": "AQPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U8P7", "type": "external" } ], "mass": 29906.0, "length": 279, "protein_name": "Aquaporin A", "gene_name": "aqpA", "organism": "Cellular slime mold", "refseq_name": "major intrinsic protein family protein", "refseq_ac": [ { "id": "XP_647526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647526", "type": "external" } ], "gene_names_uniprotkb": "aqpA; DDB_G0267378", "gene_names_refseq": "aqpA", "protein_names_uniprotkb": "Aquaporin A", "protein_names_refseq": "major intrinsic protein family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267378); (R-DDI-1237044); (R-DDI-1247673); (R-DDI-432040); (R-DDI-432047)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "10876090;15875012", "class_list": "", "function": "May form a water-specific channel (By similarity). Required for prolonged spore survival on fruiting bodies., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55FK7", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006833 water transport;GO:0006971 hypotonic response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9U8P7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U8Q1-1", "uniprot_id": [ { "id": "TGRD1_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U8Q1", "type": "external" } ], "mass": 97644.0, "length": 895, "protein_name": "Tiger protein D1", "gene_name": "tgrD1", "organism": "Cellular slime mold", "refseq_name": "IPT/TIG domain-containing protein", "refseq_ac": [ { "id": "XP_637529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_637529", "type": "external" } ], "gene_names_uniprotkb": "tgrD1; DDB_G0286825; lagC2; lagD1; lagD", "gene_names_refseq": "tgrD1", "protein_names_uniprotkb": "Tiger protein D1; Loose aggregate C2 protein; Loose aggregate D1 protein; Transmembrane, IPT, Ig, E-set, Repeat protein D1", "protein_names_refseq": "IPT/TIG domain-containing protein; immunoglobulin E-set domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0286825)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14651934;15875012;19285397", "class_list": "", "function": "May be involved in the regulation of aggregation. Activates tgrC1., [UniProtKB]", "predicted_glycosites": 28, "predicted_n_glycosites": 27, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 28, "binding_glycan_count": 0, "secondary_ac_list": "C0JMQ2;C0JMQ3;C0JMQ4;C0JMQ5;C0JMQ6;C0JMQ7;C0JMQ8;C0JMQ9;C0JMR1;C0JMR2;C0JMR3;C0JMR4;C0JMR5;C0JMR6;Q54L74", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0031152 aggregation involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9U8Q1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9U9R7-1", "uniprot_id": [ { "id": "SNAG_DICDI", "url": "https://www.uniprot.org/uniprot/Q9U9R7", "type": "external" } ], "mass": 36734.0, "length": 324, "protein_name": "Gamma-soluble NSF attachment protein", "gene_name": "snpC", "organism": "Cellular slime mold", "refseq_name": "soluble NSF attachment protein gamma isoform", "refseq_ac": [ { "id": "XP_646797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_646797", "type": "external" } ], "gene_names_uniprotkb": "snpC; DDB_G0269186", "gene_names_refseq": "snpC", "protein_names_uniprotkb": "Gamma-soluble NSF attachment protein; N-ethylmaleimide-sensitive factor attachment protein gamma; SNAP-gamma", "protein_names_refseq": "soluble NSF attachment protein gamma isoform", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0269186); (R-DDI-204005); (R-DDI-6807878); (R-DDI-6811434); (R-DDI-6811438); (R-DDI-6811440)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "10727946;12175335;15875012;16926386", "class_list": "", "function": "May be required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity). Involved in vesicle fusion with nsfA and probably SNARE proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q55BN4", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0005483 soluble NSF attachment protein activity", "go_cellular_component": "GO:0030659 cytoplasmic vesicle membrane;GO:0045335 phagocytic vesicle;GO:0031201 SNARE complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9U9R7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9UA41-1", "uniprot_id": [ { "id": "PPID_DICDI", "url": "https://www.uniprot.org/uniprot/Q9UA41", "type": "external" } ], "mass": 19016.0, "length": 174, "protein_name": "Peptidyl-prolyl cis-trans isomerase D, mitochondrial", "gene_name": "cypD", "organism": "Cellular slime mold", "refseq_name": "cyclophilin D", "refseq_ac": [ { "id": "XP_641160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641160", "type": "external" } ], "gene_names_uniprotkb": "cypD; DDB_G0280401; cyp3", "gene_names_refseq": "cypD", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase D, mitochondrial; 5.2.1.8; Cyclophilin D; PPIase D; Rotamase D", "protein_names_refseq": "cyclophilin D", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280401); (R-DDI-72163)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10575348;15875012", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54VE9", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9UA41-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9UAG7-1", "uniprot_id": [ { "id": "FHBA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9UAG7", "type": "external" } ], "mass": 43925.0, "length": 397, "protein_name": "Flavohemoprotein A", "gene_name": "fhbA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_629622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_629622", "type": "external" } ], "gene_names_uniprotkb": "fhbA; DDB_G0292378", "gene_names_refseq": "fhbA", "protein_names_uniprotkb": "Flavohemoprotein A; 1.14.12.17; DdFHa; Flavohemoglobin A; Hemoglobin-like protein A; NO oxygenase A; NOD A; Nitric oxide dioxygenase A", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0292378)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10791894;15875012", "class_list": "", "function": "In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities. However, all these reactions are much lower than NOD activity (By similarity)., [UniProtKB]; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the cell from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54D74", "ec_number_list": [ { "id": "1.14.12.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.12.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0071949 FAD binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0071333 cellular response to glucose stimulus;GO:0009636 response to toxic substance;GO:0071500 cellular response to nitrosative stress;GO:0046210 nitric oxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9UAG7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XXV8-1", "uniprot_id": [ { "id": "MYOK_DICDI", "url": "https://www.uniprot.org/uniprot/Q9XXV8", "type": "external" } ], "mass": 94364.0, "length": 858, "protein_name": "Myosin-K heavy chain", "gene_name": "myoK", "organism": "Cellular slime mold", "refseq_name": "class I myosin", "refseq_ac": [ { "id": "XP_643950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_643950", "type": "external" } ], "gene_names_uniprotkb": "myoK; DDB_G0274575; myoIG", "gene_names_refseq": "myoK", "protein_names_uniprotkb": "Myosin-K heavy chain", "protein_names_refseq": "class I myosin; myosin IK; unconventional myosin heavy chain", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0274575)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10049776;10403059;10652255;12097910;15875012;16857047", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity. Involved in phagocytosis and motility, and in the maintenance and dynamics of cell cortex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q555W0;Q86J00;Q9UA70", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0005522 profilin binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0031252 cell leading edge", "go_biological_process": "GO:0006897 endocytosis;GO:0006911 phagocytosis, engulfment;GO:0007015 actin filament organization;GO:0050766 positive regulation of phagocytosis;GO:0030866 cortical actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9XXV8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYL0-1", "uniprot_id": [ { "id": "CTDS_DICDI", "url": "https://www.uniprot.org/uniprot/Q9XYL0", "type": "external" } ], "mass": 35116.0, "length": 306, "protein_name": "Probable C-terminal domain small phosphatase", "gene_name": "fcpA", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_628708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_628708", "type": "external" } ], "gene_names_uniprotkb": "fcpA; DDB_G0294376; DG1148; ctdsp", "gene_names_refseq": "fcpA", "protein_names_uniprotkb": "Probable C-terminal domain small phosphatase; 3.1.3.16; Developmental gene 1148 protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0294376)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May function as a phosphatase involved in the regulation of cell growth and differentiation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54AK8", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006972 hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9XYL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYS3-1", "uniprot_id": [ { "id": "NOXA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9XYS3", "type": "external" } ], "mass": 59752.0, "length": 517, "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit A", "gene_name": "noxA", "organism": "Cellular slime mold", "refseq_name": "flavocytochrome b large subunit", "refseq_ac": [ { "id": "XP_636064", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_636064", "type": "external" } ], "gene_names_uniprotkb": "noxA; DDB_G0289653", "gene_names_refseq": "noxA", "protein_names_uniprotkb": "Superoxide-generating NADPH oxidase heavy chain subunit A; 1.-.-.-; NADPH oxidase A; Superoxide-generating NADPH oxidase flavocytochrome A", "protein_names_refseq": "flavocytochrome b large subunit; superoxide-generating NADPH oxidase flavocytochrome", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0289653); (R-DDI-3299685); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15875012;15950752", "class_list": "", "function": "Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54H54", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" }, { "id": "1.14.19.17", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.17", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0020037 heme binding;GO:0016175 superoxide-generating NAD(P)H oxidase activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0006952 defense response;GO:0050829 defense response to Gram-negative bacterium;GO:0042742 defense response to bacterium;GO:0031640 killing of cells of another organism;GO:0042554 superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9XYS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XYS8-1", "uniprot_id": [ { "id": "LMPA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9XYS8", "type": "external" } ], "mass": 87829.0, "length": 779, "protein_name": "Lysosome membrane protein 2-A", "gene_name": "lmpA", "organism": "Cellular slime mold", "refseq_name": "lysosomal integral membrane glycoprotein", "refseq_ac": [ { "id": "XP_647472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_647472", "type": "external" } ], "gene_names_uniprotkb": "lmpA; DDB_G0267406", "gene_names_refseq": "lmpA", "protein_names_uniprotkb": "Lysosome membrane protein 2-A; LIMP II-1; Lysosome membrane protein II-1", "protein_names_refseq": "lysosomal integral membrane glycoprotein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0267406); (R-DDI-114608); (R-DDI-434313); (R-DDI-6798695)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10189376;11489884;15875012", "class_list": "", "function": "May act as a lysosomal receptor (By similarity). May be involved in macropinocytosis and fluid phase exocytosis. Binds to the anionic phospholipid phosphoinositol 4,5-bisphosphate, but not to phosphatidylcholine and only weakly to phosphatidylserine., [UniProtKB]", "predicted_glycosites": 20, "predicted_n_glycosites": 19, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 20, "binding_glycan_count": 0, "secondary_ac_list": "Q55FR1", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding", "go_cellular_component": "GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0032010 phagolysosome;GO:0045335 phagocytic vesicle;GO:0044354 macropinosome", "go_biological_process": "GO:0090383 phagosome acidification;GO:0006911 phagocytosis, engulfment;GO:0050830 defense response to Gram-positive bacterium;GO:0000281 mitotic cytokinesis;GO:0001845 phagolysosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9XYS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XZE5-1", "uniprot_id": [ { "id": "PP2AA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9XZE5", "type": "external" } ], "mass": 35186.0, "length": 306, "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit A", "gene_name": "pho2a", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase 2A catalytic subunit", "refseq_ac": [ { "id": "XP_635791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_635791", "type": "external" } ], "gene_names_uniprotkb": "pho2a; DDB_G0290263; PP2Ac; PP2A", "gene_names_refseq": "pho2A", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A catalytic subunit A; 3.1.3.16; Protein phosphatase 2A 37 kDa catalytic subunit", "protein_names_refseq": "protein phosphatase 2A catalytic subunit; protein phosphatase 2A subunit C", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0290263); (R-DDI-113501); (R-DDI-198753); (R-DDI-202670); (R-DDI-389513); (R-DDI-5675221); (R-DDI-6811558); (R-DDI-69231); (R-DDI-69273); (R-DDI-9833482)", "pathway_count": 10, "publication_count": 4, "publication_id_list": "10452519;10491107;15875012;18673380", "class_list": "", "function": "Plays a role in activating the myosin contractile function. Dephosphorylates threonine at 'Thr-1823', 'Thr-1833' and 'Thr-2029' in the C-terminal tail region of myosin II heavy chain (mhcA). Drives the assembly of dephosphorylated myosin II filaments to allow myosin recruitment into the cytoskeleton., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54G92", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.1.1.233", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.233", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.1.89", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.89", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0017018 myosin phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:0031034 myosin filament assembly;GO:0000278 mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9XZE5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Y0B7-1", "uniprot_id": [ { "id": "PP4C_DICDI", "url": "https://www.uniprot.org/uniprot/Q9Y0B7", "type": "external" } ], "mass": 34862.0, "length": 305, "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "ppp4c", "organism": "Cellular slime mold", "refseq_name": "protein phosphatase 4 catalytic subunit", "refseq_ac": [ { "id": "XP_645186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_645186", "type": "external" } ], "gene_names_uniprotkb": "ppp4c; DDB_G0272116; pppC", "gene_names_refseq": "ppp4C", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 4 catalytic subunit; 3.1.3.16; PP4C", "protein_names_refseq": "protein phosphatase 4 catalytic subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0272116)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10454741;12097910;15875012;17353263", "class_list": "", "function": "Required for development, chemotaxis and the expression of numerous genes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q559Z8", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030289 protein phosphatase 4 complex", "go_biological_process": "GO:0050920 regulation of chemotaxis;GO:0000724 double-strand break repair via homologous recombination;GO:0031156 regulation of sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9Y0B7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Y0T2-1", "uniprot_id": [ { "id": "FBXA_DICDI", "url": "https://www.uniprot.org/uniprot/Q9Y0T2", "type": "external" } ], "mass": 142388.0, "length": 1247, "protein_name": "F-box/WD repeat-containing protein A", "gene_name": "fbxA", "organism": "Cellular slime mold", "refseq_name": "F-box-containing protein", "refseq_ac": [ { "id": "XP_642882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_642882", "type": "external" } ], "gene_names_uniprotkb": "fbxA; DDB_G0276887; chtA", "gene_names_refseq": "fbxA", "protein_names_uniprotkb": "F-box/WD repeat-containing protein A; F-box protein A; Protein cheater A", "protein_names_refseq": "F-box-containing protein; START domain-containing protein; WD40 repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0276887)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10725352;10898960;11390363;12097910;12796307;15875012;17496139", "class_list": "", "function": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May target the cAMP phosphodiesterase regA for degradation leading to an increase in cAMP and PKA activity. Promotes development of prestalk cells as opposed to prespores within the developing fruiting body. Required for culmination and fruiting body development., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q550Q0;Q9U9T1;Q9U9U5", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0030154 cell differentiation;GO:0045595 regulation of cell differentiation;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030435 sporulation resulting in formation of a cellular spore;GO:0031154 culmination involved in sorocarp development", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9Y0T2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9Y1W0-1", "uniprot_id": [ { "id": "FAD5A_DICDI", "url": "https://www.uniprot.org/uniprot/Q9Y1W0", "type": "external" } ], "mass": 54005.0, "length": 464, "protein_name": "Delta(5) fatty acid desaturase A", "gene_name": "fadA", "organism": "Cellular slime mold", "refseq_name": "delta 5 fatty acid desaturase", "refseq_ac": [ { "id": "XP_638329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_638329", "type": "external" } ], "gene_names_uniprotkb": "fadA; DDB_G0285211; des5-1", "gene_names_refseq": "fadA", "protein_names_uniprotkb": "Delta(5) fatty acid desaturase A; 1.14.19.-; Delta-5 fatty acid desaturase A", "protein_names_refseq": "delta 5 fatty acid desaturase", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0285211)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10504413;15632431;15875012", "class_list": "", "function": "Specific for desaturation of the 5 position in C16 and C18 fatty acids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q54NI8", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016491 oxidoreductase activity;GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;GO:0062076 acyl-CoA (8-3)-desaturase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006631 fatty acid metabolic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9Y1W0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RU1-1", "uniprot_id": [ { "id": "ABCB6_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RU1", "type": "external" } ], "mass": 76921.0, "length": 678, "protein_name": "ABC transporter B family member 6", "gene_name": "abcB6", "organism": "Cellular slime mold", "refseq_name": "ABC transporter B family protein", "refseq_ac": [ { "id": "XP_639260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639260", "type": "external" } ], "gene_names_uniprotkb": "abcB6; DDB_G0282931", "gene_names_refseq": "abcB6", "protein_names_uniprotkb": "ABC transporter B family member 6; ABC transporter ABCB.6", "protein_names_refseq": "ABC transporter B family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282931); (R-DDI-159418); (R-DDI-193368); (R-DDI-382556); (R-DDI-9754706); (R-DDI-9757110); (R-DDI-983170)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54RU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RV6-1", "uniprot_id": [ { "id": "TPPC2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RV6", "type": "external" } ], "mass": 15686.0, "length": 133, "protein_name": "Trafficking protein particle complex subunit 2", "gene_name": "trappc2", "organism": "Cellular slime mold", "refseq_name": "trafficking protein particle complex subunit 2", "refseq_ac": [ { "id": "XP_639381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639381", "type": "external" } ], "gene_names_uniprotkb": "trappc2; DDB_G0282887", "gene_names_refseq": "trappc2", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 2", "protein_names_refseq": "trafficking protein particle complex subunit 2", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282887); (R-DDI-204005); (R-DDI-8876198)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "May play a role in vesicular transport from endoplasmic reticulum to Golgi., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54RV6-1", 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"https://www.ncbi.nlm.nih.gov/protein/XP_639372", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282873", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding region RNP-1 domain-containing protein", "protein_names_refseq": "RNA recognition motif-containing protein RRM; RNA-binding region RNP-1 domain-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282873)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi;GO:0099041 vesicle tethering to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54RW5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RX1-1", "uniprot_id": [ { "id": "TCTP2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RX1", "type": "external" } ], "mass": 22069.0, "length": 194, "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "DDB_G0282861", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_639366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639366", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282861", "gene_names_refseq": "", "protein_names_uniprotkb": "Translationally-controlled tumor protein homolog 2; TCTP 2", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282861)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Involved in calcium binding 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10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0010507 negative regulation of autophagy;GO:0006887 exocytosis;GO:0006907 pinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54RX1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54RX2-1", "uniprot_id": [ { "id": "Q54RX2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54RX2", "type": "external" } ], "mass": 72374.0, "length": 629, "protein_name": "Calponin-homology (CH) domain-containing protein", "gene_name": "DDB_G0282859", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_639365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_639365", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282859", "gene_names_refseq": "", "protein_names_uniprotkb": "Calponin-homology (CH) domain-containing protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282859); (R-DDI-114608); (R-DDI-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. 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DDB_G0282623", "gene_names_refseq": "wdr3", "protein_names_uniprotkb": "WD repeat-containing protein 3 homolog", "protein_names_refseq": "U3 small nucleolar ribonucleoprotein; U3 snoRNP protein; WD40 repeat-containing protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282623); (R-DDI-6791226)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030515 snoRNA binding", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54S79-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S82-1", "uniprot_id": [ { "id": "Q54S82_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S82", "type": "external" } ], "mass": 36411.0, "length": 326, "protein_name": "Proteasome inhibitor PI31 subunit", "gene_name": "psmF1", "organism": "Cellular slime mold", "refseq_name": "proteasome inhibitor PI31 subunit", "refseq_ac": [ { "id": "XP_640157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640157", "type": "external" } ], "gene_names_uniprotkb": "psmF1; DDB_G0282617", "gene_names_refseq": "psmF1", "protein_names_uniprotkb": "Proteasome inhibitor PI31 subunit", "protein_names_refseq": "proteasome inhibitor PI31 subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282617)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"go_biological_process": "GO:0046513 ceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54S87-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54S90-1", "uniprot_id": [ { "id": "RS11_DICDI", "url": "https://www.uniprot.org/uniprot/Q54S90", "type": "external" } ], "mass": 17817.0, "length": 155, "protein_name": "Small ribosomal subunit protein uS17", "gene_name": "rps11", "organism": "Cellular slime mold", "refseq_name": "40S ribosomal protein S11", "refseq_ac": [ { "id": "XP_640149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640149", "type": "external" } ], "gene_names_uniprotkb": "rps11; DDB_G0282601", "gene_names_refseq": "rps11", "protein_names_uniprotkb": "Small ribosomal subunit protein uS17; 40S ribosomal protein S11", "protein_names_refseq": "40S ribosomal protein S11", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282601); (R-DDI-156827); (R-DDI-1799339); (R-DDI-6791226); (R-DDI-72689); (R-DDI-72695); (R-DDI-72702); (R-DDI-72706); (R-DDI-975956); (R-DDI-975957); (R-DDI-9954714); (R-DDI-9954716)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, 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} ], "mass": 42479.0, "length": 362, "protein_name": "Protein FAM50 homolog", "gene_name": "fam50", "organism": "Cellular slime mold", "refseq_name": "XAP-5 protein", "refseq_ac": [ { "id": "XP_640145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640145", "type": "external" } ], "gene_names_uniprotkb": "fam50; DDB_G0282593", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein FAM50 homolog", "protein_names_refseq": "XAP-5 protein; XAP5 protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282593); (R-DDI-72163)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, 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0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54SG7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SG9-1", "uniprot_id": [ { "id": "Q54SG9_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SG9", "type": "external" } ], "mass": 104712.0, "length": 932, "protein_name": "DH domain-containing protein", "gene_name": "gxcF", "organism": "Cellular slime mold", "refseq_name": "RhoGEF 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"kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SH0-1", "uniprot_id": [ { "id": "INT9_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SH0", "type": "external" } ], "mass": 81490.0, "length": 712, "protein_name": "Integrator complex subunit 9 homolog", "gene_name": "ints9", "organism": "Cellular slime mold", "refseq_name": "integrator complex subunit 9", "refseq_ac": [ { "id": "XP_640069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640069", "type": "external" } ], "gene_names_uniprotkb": "ints9; DDB_G0282473", "gene_names_refseq": "ints9", "protein_names_uniprotkb": "Integrator complex subunit 9 homolog", "protein_names_refseq": "integrator complex subunit 9", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282473); (R-DDI-6807505)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in 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The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit polr2a, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54SH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SH2-1", "uniprot_id": [ { "id": "GNT13_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SH2", "type": "external" } ], "mass": 73802.0, "length": 635, "protein_name": "Glycosyltransferase-like protein gnt13", "gene_name": "gnt13", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640067", "type": "external" } ], "gene_names_uniprotkb": "gnt13; DDB_G0282469", "gene_names_refseq": "gnt13", "protein_names_uniprotkb": "Glycosyltransferase-like protein gnt13", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282469)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15875012;17588537", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042285 xylosyltransferase activity;GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0035269 protein O-linked glycosylation via mannose", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54SH2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SI1-1", "uniprot_id": [ { "id": "MED1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SI1", "type": "external" } ], "mass": 83687.0, "length": 724, "protein_name": "Putative mediator of RNA polymerase II transcription subunit 1", "gene_name": "med1", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640058", "type": "external" } ], "gene_names_uniprotkb": "med1; 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Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54SI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54SI2-1", "uniprot_id": [ { "id": "Q54SI2_DICDI", "url": "https://www.uniprot.org/uniprot/Q54SI2", "type": "external" } ], "mass": 55844.0, "length": 488, "protein_name": "6-phosphofructo-2-kinase domain-containing protein", "gene_name": "DDB_G0282759", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640057", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0282759", "gene_names_refseq": "", "protein_names_uniprotkb": "6-phosphofructo-2-kinase domain-containing protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0282759); 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May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0047429 nucleoside triphosphate diphosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009117 nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TC5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TC6-1", "uniprot_id": [ { "id": "BL1S5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TC6", "type": "external" } ], "mass": 18729.0, "length": 158, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 5", "gene_name": "bloc1s5", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640463", "type": "external" } ], "gene_names_uniprotkb": "bloc1s5; DDB_G0281859; muted", "gene_names_refseq": "", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit 5; BLOC-1 subunit 5; Protein Muted homolog", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281859)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). May play a role in intracellular vesicle trafficking (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030133 transport vesicle;GO:0031083 BLOC-1 complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TC6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TD1-1", "uniprot_id": [ { "id": "Q54TD1_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TD1", "type": "external" } ], "mass": 177869.0, "length": 1630, "protein_name": "IPT/TIG domain-containing protein", "gene_name": "DDB_G0281853", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_640458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640458", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0281853", "gene_names_refseq": "", "protein_names_uniprotkb": "IPT/TIG domain-containing protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281853)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0009617 response to bacterium;GO:0006907 pinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54TD1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54TD3-1", "uniprot_id": [ { "id": "TCPE_DICDI", "url": "https://www.uniprot.org/uniprot/Q54TD3", "type": "external" } ], "mass": 59130.0, "length": 538, "protein_name": "T-complex protein 1 subunit epsilon", "gene_name": "cct5", "organism": "Cellular slime mold", "refseq_name": "chaperonin containing TCP1 epsilon subunit", "refseq_ac": [ { "id": "XP_640456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_640456", "type": "external" } ], "gene_names_uniprotkb": "cct5; DDB_G0281849", "gene_names_refseq": "cct5", "protein_names_uniprotkb": "T-complex protein 1 subunit epsilon; CCT-epsilon; TCP-1-epsilon", "protein_names_refseq": "chaperonin containing TCP1 epsilon subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0281849); (R-DDI-390471); (R-DDI-6814122)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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DDB_G0280537", "gene_names_refseq": "wacA", "protein_names_uniprotkb": "Aquaporin C; Aquaporin-like protein wacA; Water channel protein A", "protein_names_refseq": "aquaporin-like protein; major intrinsic protein family protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280537); (R-DDI-1237044); (R-DDI-1247673); (R-DDI-432040); (R-DDI-432047)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15875012;9305756", "class_list": "", "function": "May form a water-specific channel., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q94495", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006833 water transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q54V53-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V54-1", "uniprot_id": [ { "id": "OST4_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V54", "type": "external" } ], "mass": 4447.0, "length": 40, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "ost4", "organism": "Cellular slime mold", "refseq_name": "dolichyl-diphosphooligosaccharide-protein glycotransferase", "refseq_ac": [ { "id": "XP_641077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641077", "type": "external" } ], "gene_names_uniprotkb": "ost4; DDB_G0280609", "gene_names_refseq": "ost4", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "protein_names_refseq": "dolichyl-diphosphooligosaccharide-protein glycotransferase; oligosaccharyltransferase 3.6 kDa subunit", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280609)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54V54-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V55-1", "uniprot_id": [ { "id": "PFD5_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V55", "type": "external" } ], "mass": 18008.0, "length": 160, "protein_name": "Probable prefoldin subunit 5", "gene_name": "pfdn5", "organism": "Cellular slime mold", "refseq_name": "prefoldin alpha-like domain containing protein", "refseq_ac": [ { "id": "XP_641076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641076", "type": "external" } ], "gene_names_uniprotkb": "pfdn5; DDB_G0280607", "gene_names_refseq": "pfdn5", "protein_names_uniprotkb": "Probable prefoldin subunit 5", "protein_names_refseq": "prefoldin alpha-like domain containing protein; prefoldin subunit 5", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280607)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016272 prefoldin complex", "go_biological_process": "GO:0006457 protein folding;GO:1990114 RNA polymerase II core complex assembly;GO:1990113 RNA polymerase I assembly;GO:1990115 RNA polymerase III assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54V55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V57-1", "uniprot_id": [ { "id": "Q54V57_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V57", "type": "external" } ], "mass": 120133.0, "length": 1015, "protein_name": "SP-RING-type domain-containing protein", "gene_name": "DDB_G0280603", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641074", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0280603", "gene_names_refseq": "", "protein_names_uniprotkb": "SP-RING-type domain-containing protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280603); (R-DDI-3108214); (R-DDI-3232118); (R-DDI-3899300); (R-DDI-4085377); (R-DDI-4615885); (R-DDI-5696395); (R-DDI-877312)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061665 SUMO ligase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0000785 chromatin", "go_biological_process": "GO:0016925 protein sumoylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54V57-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V61-1", "uniprot_id": [ { "id": "NDUB7_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V61", "type": "external" } ], "mass": 13271.0, "length": 112, "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "gene_name": "ndufb7", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641070", "type": "external" } ], "gene_names_uniprotkb": "ndufb7; DDB_G0280595", "gene_names_refseq": "", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280595)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54V61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V63-1", "uniprot_id": [ { "id": "Q54V63_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V63", "type": "external" } ], "mass": 106669.0, "length": 946, "protein_name": "Atos-like conserved domain-containing protein", "gene_name": "DDB_G0280593", "organism": "Cellular slime mold", "refseq_name": "hypothetical protein", "refseq_ac": [ { "id": "XP_641068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_641068", "type": "external" } ], "gene_names_uniprotkb": "DDB_G0280593", "gene_names_refseq": "", "protein_names_uniprotkb": "Atos-like conserved domain-containing protein", "protein_names_refseq": "hypothetical protein", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280593)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q54V63-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.001000000000000000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q54V76-1", "uniprot_id": [ { "id": "QCR8_DICDI", "url": "https://www.uniprot.org/uniprot/Q54V76", "type": "external" } ], "mass": 8687.0, "length": 73, "protein_name": "Probable cytochrome b-c1 complex subunit 8", "gene_name": "DDB_G0280569", "organism": "Cellular slime mold", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DDB_G0280569", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable cytochrome b-c1 complex subunit 8; Ubiquinol-cytochrome c reductase complex subunit 8", "protein_names_refseq": "", "tax_id": 44689, "disease": "", "pathway": " (ddi:DDB_G0280569); (R-DDI-611105); (R-DDI-9837999)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15875012", "class_list": "", "function": "Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. 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