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            {
                "id": "A0AB32T1K2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T1K2",
                "type": "external"
            }
        ],
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        "length": 270,
        "protein_name": "Protein FAM13A isoform X1",
        "gene_name": "LOC101886572",
        "organism": "Zebrafish",
        "refseq_name": "protein FAM13A isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068069727",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069727",
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            }
        ],
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        "gene_names_refseq": "LOC101886572",
        "protein_names_uniprotkb": "Protein FAM13A isoform X1",
        "protein_names_refseq": "protein FAM13A isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101886572)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [],
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        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction",
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        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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        "uniprot_id": [
            {
                "id": "A0AB32T1L0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T1L0",
                "type": "external"
            }
        ],
        "mass": 36739.0,
        "length": 316,
        "protein_name": "Formyl peptide receptor 2-like",
        "gene_name": "LOC100331422",
        "organism": "Zebrafish",
        "refseq_name": "formyl peptide receptor 2-like",
        "refseq_ac": [
            {
                "id": "XP_068069741",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069741",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100331422",
        "gene_names_refseq": "LOC100331422",
        "protein_names_uniprotkb": "Formyl peptide receptor 2-like",
        "protein_names_refseq": "formyl peptide receptor 2-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100331422)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 10% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "",
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        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
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    {
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        "uniprot_id": [
            {
                "id": "A0AB32T1L1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T1L1",
                "type": "external"
            }
        ],
        "mass": 116610.0,
        "length": 1030,
        "protein_name": "Ig-like domain-containing protein",
        "gene_name": "LOC101883854",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_068069742",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069742",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101883854",
        "gene_names_refseq": "LOC101883854",
        "protein_names_uniprotkb": "Ig-like domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101883854)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069742.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32T1L1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0AB32T1M8-1",
        "uniprot_id": [
            {
                "id": "A0AB32T1M8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T1M8",
                "type": "external"
            }
        ],
        "mass": 33187.0,
        "length": 287,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137487709",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068069757",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069757",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137487709",
        "gene_names_refseq": "LOC137487709",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487709)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069757.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AB32T1M8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AB32T1M9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T1M9",
                "type": "external"
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        ],
        "mass": 35362.0,
        "length": 301,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC137487708",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_068069756",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069756",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137487708",
        "gene_names_refseq": "LOC137487708",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487708)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069756.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding",
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        "go_biological_process": "GO:0006351 DNA-templated transcription",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0AB32T1T2",
                "type": "external"
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        ],
        "mass": 88943.0,
        "length": 804,
        "protein_name": "Protocadherin alpha-C2 isoform X1",
        "gene_name": "si:ch73-233f7.7",
        "organism": "Zebrafish",
        "refseq_name": "protocadherin alpha-C2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068069383",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069383",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-233f7.7",
        "gene_names_refseq": "si:ch73-233f7.7",
        "protein_names_uniprotkb": "Protocadherin alpha-C2 isoform X1",
        "protein_names_refseq": "protocadherin alpha-C2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110440215)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069383.1. COMPLETENESS: full length., [RefSeq]; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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            {
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Putative monooxygenase p33MONOX",
        "gene_name": "si:dkeyp-44a8.2",
        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069397",
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        "protein_names_uniprotkb": "Putative monooxygenase p33MONOX",
        "protein_names_refseq": "putative monooxygenase p33MONOX",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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                "id": "XP_068069847",
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        "gene_names_refseq": "LOC137487757",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069847.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "palmitoyl-CoA hydrolase",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069877",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the cleavage of thioester bonds from S-palmitoyl-CoA or S-palmitoyl-N-acetylcysteamine (unbranched structures) but does not have activity against palmitoylcysteine or palmitoylated proteins, branched structures or bulky head groups. Conversely, hydrolyzes both long and short chain fatty acyl-CoA substrate., [UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "Trace amine-associated receptor 13c-like",
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        "length": 154,
        "protein_name": "Cystatin-like protein",
        "gene_name": "si:dkeyp-73d8.8",
        "organism": "Zebrafish",
        "refseq_name": "cystatin-like protein",
        "refseq_ac": [
            {
                "id": "XP_068070313",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070313",
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        "gene_names_uniprotkb": "si:dkeyp-73d8.8",
        "gene_names_refseq": "si:dkeyp-73d8.8",
        "protein_names_uniprotkb": "Cystatin-like protein",
        "protein_names_refseq": "cystatin-like protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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            {
                "id": "A0AB32T399_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T399",
                "type": "external"
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        ],
        "mass": 20253.0,
        "length": 185,
        "protein_name": "Cysteine-rich venom protein natrin-1",
        "gene_name": "LOC100536500",
        "organism": "Zebrafish",
        "refseq_name": "cysteine-rich venom protein natrin-1",
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            {
                "id": "XP_073782870",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073782870",
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        ],
        "gene_names_uniprotkb": "LOC100536500",
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        "protein_names_uniprotkb": "Cysteine-rich venom protein natrin-1",
        "protein_names_refseq": "cysteine-rich venom protein natrin-1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58HLK8",
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    {
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            {
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        ],
        "mass": 89100.0,
        "length": 801,
        "protein_name": "Protocadherin alpha-C2",
        "gene_name": "LOC103908739",
        "organism": "Zebrafish",
        "refseq_name": "protocadherin alpha-C2",
        "refseq_ac": [
            {
                "id": "XP_068069522",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069522",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC103908739",
        "gene_names_refseq": "LOC103908739",
        "protein_names_uniprotkb": "Protocadherin alpha-C2",
        "protein_names_refseq": "protocadherin alpha-C2",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069522.1. COMPLETENESS: full length., [RefSeq]; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005509 calcium ion binding",
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    {
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137487516",
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        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068069366",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069366",
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        ],
        "gene_names_uniprotkb": "LOC137487516",
        "gene_names_refseq": "LOC137487516",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "mass": 126955.0,
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        "protein_name": "Potassium channel subfamily T member 2 isoform X1",
        "gene_name": "kcnt2a",
        "organism": "Zebrafish",
        "refseq_name": "potassium channel subfamily T member 2 isoform X1",
        "refseq_ac": [
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        "gene_names_uniprotkb": "kcnt2a",
        "gene_names_refseq": "kcnt2a",
        "protein_names_uniprotkb": "Potassium channel subfamily T member 2 isoform X1",
        "protein_names_refseq": "potassium channel subfamily T member 2 isoform X1",
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        "disease": "developmental and epileptic encephalopathy 57 (Disease Ontology:DOID:0080284); epilepsy (Disease Ontology:DOID:1826)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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                "id": "A0AB32T576_DANRE",
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        ],
        "mass": 82986.0,
        "length": 741,
        "protein_name": "Neurogranin (Protein kinase C substrate, RC3) b isoform X1",
        "gene_name": "spa17",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069704",
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        "gene_names_uniprotkb": "spa17; nrgnb; zgc:158686",
        "gene_names_refseq": "nrgnb; zgc:158686",
        "protein_names_uniprotkb": "Neurogranin (Protein kinase C substrate, RC3) b isoform X1",
        "protein_names_refseq": "neurogranin (protein kinase C substrate, RC3) b isoform X1",
        "tax_id": 7955,
        "disease": "Merkel cell carcinoma (Disease Ontology:DOID:3965)",
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        ],
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        "gene_name": "eml5",
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        "protein_names_refseq": "echinoderm microtubule-associated protein-like 5 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "gene_names_uniprotkb": "si:dkey-112g5.14; si:busm1-sl7.7",
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        "protein_names_refseq": "serine protease HTRA2, mitochondrial isoform X1",
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        "predicted_glycosites": 0,
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069751",
                "type": "external"
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        ],
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        "gene_names_refseq": "LOC137487706",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        ],
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        "protein_name": "Extracellular calcium-sensing receptor-like",
        "gene_name": "LOC103909158",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.19039671.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Sep 16, 2025 this sequence version replaced XP_068070948.1., [RefSeq]",
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        "gene_names_refseq": "ryr2b; ryrbb",
        "protein_names_uniprotkb": "Ryanodine receptor 2",
        "protein_names_refseq": "ryanodine receptor 2b protein; ryanodine receptor 2; ryr2",
        "tax_id": 7955,
        "disease": "arrhythmogenic right ventricular cardiomyopathy (Disease Ontology:DOID:0050431); catecholaminergic polymorphic ventricular tachycardia 1 (Disease Ontology:DOID:0060675); pre-eclampsia (Disease Ontology:DOID:10591); heart disease (Disease Ontology:DOID:114); gestational diabetes (Disease Ontology:DOID:11714); alcohol use disorder (Disease Ontology:DOID:1574); congenital myopathy 1A (Disease Ontology:DOID:3529); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); malignant hyperthermia (Disease Ontology:DOID:8545)",
        "pathway": " (dre:568463)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Aug 20, 2025 this sequence version replaced XP_068070675.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 10,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "1.5.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005219 ryanodine-sensitive calcium-release channel activity",
        "go_cellular_component": "GO:0033017 sarcoplasmic reticulum membrane",
        "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32T6W5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.000100.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32T6Y5-1",
        "uniprot_id": [
            {
                "id": "A0AB32T6Y5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T6Y5",
                "type": "external"
            }
        ],
        "mass": 41451.0,
        "length": 357,
        "protein_name": "GTPase IMAP family member 7-like",
        "gene_name": "LOC137487402",
        "organism": "Zebrafish",
        "refseq_name": "GTPase IMAP family member 7-like",
        "refseq_ac": [
            {
                "id": "XP_068069151",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069151",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137487402",
        "gene_names_refseq": "LOC137487402",
        "protein_names_uniprotkb": "GTPase IMAP family member 7-like",
        "protein_names_refseq": "GTPase IMAP family member 7-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487402)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069151.1. COMPLETENESS: incomplete on the amino end., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005525 GTP binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32T6Y5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32T6Z7-1",
        "uniprot_id": [
            {
                "id": "A0AB32T6Z7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T6Z7",
                "type": "external"
            }
        ],
        "mass": 100144.0,
        "length": 909,
        "protein_name": "E-selectin",
        "gene_name": "selp",
        "organism": "Zebrafish",
        "refseq_name": "P-selectin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068071669",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071669",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "selp; si:ch211-260g14.4",
        "gene_names_refseq": "selp; si:ch211-260g14.4",
        "protein_names_uniprotkb": "E-selectin; CD62 antigen-like family member E; Endothelial leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 2",
        "protein_names_refseq": "P-selectin isoform X1",
        "tax_id": 7955,
        "disease": "colitis (Disease Ontology:DOID:0060180); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); brain small vessel disease (Disease Ontology:DOID:0112313); aortic atherosclerosis (Disease Ontology:DOID:10230); Alzheimer's disease (Disease Ontology:DOID:10652); Sjogren's syndrome (Disease Ontology:DOID:12894); Kawasaki disease (Disease Ontology:DOID:13378); atherosclerosis (Disease Ontology:DOID:1936); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); atopic dermatitis (Disease Ontology:DOID:3310); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); ulcerative colitis (Disease Ontology:DOID:8577); intermediate coronary syndrome (Disease Ontology:DOID:8805); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
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        "mined_glycosites": 0,
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        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 19,
        "glyco_site_count": 1,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0097241 hematopoietic stem cell migration to bone marrow;GO:0007155 cell adhesion;GO:0030097 hemopoiesis;GO:0035701 hematopoietic stem cell migration",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32T6Z7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32T720-1",
        "uniprot_id": [
            {
                "id": "A0AB32T720_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T720",
                "type": "external"
            }
        ],
        "mass": 103882.0,
        "length": 931,
        "protein_name": "MutS protein homolog 4 isoform X1",
        "gene_name": "msh4",
        "organism": "Zebrafish",
        "refseq_name": "mutS protein homolog 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068070735",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070735",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "msh4",
        "gene_names_refseq": "msh4",
        "protein_names_uniprotkb": "MutS protein homolog 4 isoform X1",
        "protein_names_refseq": "mutS protein homolog 4 isoform X1",
        "tax_id": 7955,
        "disease": "spermatogenic failure 2 (Disease Ontology:DOID:0070164); primary ovarian insufficiency (Disease Ontology:DOID:5426)",
        "pathway": " (dre:559917)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the post-replicative DNA mismatch repair system (MMR)., [UniProtKB, UniProtKB, UniProtKB]",
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0AC58HPE0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0003690 double-stranded DNA binding",
        "go_cellular_component": "GO:0032301 MutSalpha complex;GO:0005634 nucleus",
        "go_biological_process": "GO:0006298 mismatch repair;GO:0051321 meiotic cell cycle;GO:0007131 reciprocal meiotic recombination",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32T720-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32T733-1",
        "uniprot_id": [
            {
                "id": "A0AB32T733_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T733",
                "type": "external"
            }
        ],
        "mass": 12480.0,
        "length": 115,
        "protein_name": "Protein LBH",
        "gene_name": "si:ch73-49p17.1",
        "organism": "Zebrafish",
        "refseq_name": "protein LBH",
        "refseq_ac": [
            {
                "id": "XP_068069100",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069100",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-49p17.1",
        "gene_names_refseq": "si:ch73-49p17.1",
        "protein_names_uniprotkb": "Protein LBH",
        "protein_names_refseq": "protein LBH",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100321135)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "missing_score": 10000,
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        "record_id": "A0AB32T733-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AB32T775_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T775",
                "type": "external"
            }
        ],
        "mass": 16247.0,
        "length": 142,
        "protein_name": "Uncharacterized protein si:ch211-195o19.4",
        "gene_name": "si:ch211-195o19.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-195o19.4",
        "refseq_ac": [
            {
                "id": "XP_068071728",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071728",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-195o19.4",
        "gene_names_refseq": "si:ch211-195o19.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-195o19.4",
        "protein_names_refseq": "uncharacterized protein si:ch211-195o19.4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:108180310)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
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    {
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            {
                "id": "A0AB32T780_DANRE",
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        ],
        "mass": 46833.0,
        "length": 421,
        "protein_name": "Ig-like domain-containing protein",
        "gene_name": "LOC137487702",
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            {
                "id": "XP_068069744",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069744",
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        "gene_names_refseq": "LOC137487702",
        "protein_names_uniprotkb": "Ig-like domain-containing protein",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069744.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Protein cornichon homolog 3 isoform X1",
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            {
                "id": "XP_068071774",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071774",
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        "protein_names_uniprotkb": "Protein cornichon homolog 3 isoform X1",
        "protein_names_refseq": "protein cornichon homolog 3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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        "protein_name": "Insulin",
        "gene_name": "insb",
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        "refseq_ac": [
            {
                "id": "XP_068069331",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069331",
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        "gene_names_refseq": "insb",
        "protein_names_uniprotkb": "Insulin",
        "protein_names_refseq": "preproinsulin b isoform X1",
        "tax_id": 7955,
        "disease": "disease of metabolism (Disease Ontology:DOID:0014667); maturity-onset diabetes of the young (Disease Ontology:DOID:0050524); permanent neonatal diabetes mellitus (Disease Ontology:DOID:0060639); type 1 diabetes mellitus 2 (Disease Ontology:DOID:0110741); maturity-onset diabetes of the young type 10 (Disease Ontology:DOID:0111108); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); gestational diabetes (Disease Ontology:DOID:11714); neonatal diabetes mellitus (Disease Ontology:DOID:11717); pancreatic cancer (Disease Ontology:DOID:1793); hyperuricemia (Disease Ontology:DOID:1920); hyperinsulinism (Disease Ontology:DOID:2018); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); insulinoma (Disease Ontology:DOID:3892); cholangiocarcinoma (Disease Ontology:DOID:4947); sleep disorder (Disease Ontology:DOID:535); osteoarthritis (Disease Ontology:DOID:8398); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); type 1 diabetes mellitus (Disease Ontology:DOID:9744)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005576 extracellular region",
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    {
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        ],
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        "protein_name": "Ferric reductase 1",
        "gene_name": "frrs1a",
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        "refseq_ac": [
            {
                "id": "XP_068069925",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069925",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "frrs1a",
        "gene_names_refseq": "frrs1a",
        "protein_names_uniprotkb": "Ferric reductase 1",
        "protein_names_refseq": "putative ferric-chelate reductase 1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069925.1. COMPLETENESS: full length., [RefSeq]; Ferric reductase that reduces Fe(3+) to Fe(2+) and could play a role in iron import into cells. The electron donor and therefore the reaction mechanism are not known., [UniProtKB, UniProtKB]",
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        "mass": 79712.0,
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        "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1 isoform X1",
        "gene_name": "ankef1b",
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        "refseq_name": "ankyrin repeat and EF-hand domain-containing protein 1 isoform X1",
        "refseq_ac": [
            {
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        "protein_names_uniprotkb": "Ankyrin repeat and EF-hand domain-containing protein 1 isoform X1",
        "protein_names_refseq": "ankyrin repeat and EF-hand domain-containing protein 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 386,
        "protein_name": "Immunity-related GTPase family, e4 isoform X1",
        "gene_name": "irge4",
        "organism": "Zebrafish",
        "refseq_name": "immunity-related GTPase family, e4 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069940",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "irge4; zgc:158767",
        "gene_names_refseq": "irge4; zgc:158767",
        "protein_names_uniprotkb": "Immunity-related GTPase family, e4 isoform X1",
        "protein_names_refseq": "immunity-related GTPase family, e4 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Mitochondrial pyruvate carrier",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_names_refseq": "coiled-coil domain-containing protein 150 isoform X1",
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        "gene_name": "znf970",
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        "gene_names_refseq": "znf970",
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        "protein_names_refseq": "uncharacterized protein znf970 isoform X1",
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        ],
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        "protein_name": "Paired box protein Pax-1a isoform X1",
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        "length": 459,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069899.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "protein_names_uniprotkb": "LOW QUALITY PROTEIN: uncharacterized protein",
        "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein",
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        "refseq_ac": [
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
        "mass": 16727.0,
        "length": 149,
        "protein_name": "NK-lysin tandem duplicate 3 isoform X1",
        "gene_name": "nkl.3",
        "organism": "Zebrafish",
        "refseq_name": "NK-lysin tandem duplicate 3 isoform X1",
        "refseq_ac": [
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                "id": "XP_068070415",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070415",
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        ],
        "gene_names_uniprotkb": "nkl.3; Nk-lysin; nklc; si:rp71-40n14.6",
        "gene_names_refseq": "Nk-lysin; nkl.3; nklc; si:rp71-40n14.6",
        "protein_names_uniprotkb": "NK-lysin tandem duplicate 3 isoform X1",
        "protein_names_refseq": "NK-lysin tandem duplicate 3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068070415.1. COMPLETENESS: full length., [RefSeq]",
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        "mass": 94599.0,
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        "protein_name": "Liprin-beta-2 isoform X1",
        "gene_name": "ppfibp2a",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071013",
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        "gene_names_uniprotkb": "ppfibp2a",
        "gene_names_refseq": "ppfibp2a",
        "protein_names_uniprotkb": "Liprin-beta-2 isoform X1",
        "protein_names_refseq": "liprin-beta-2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Golgi resident protein GCP60",
        "gene_name": "acbd3",
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        "refseq_name": "Golgi resident protein GCP60 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068071508",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071508",
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        ],
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        "gene_names_refseq": "acbd3; fa20g08; si:dkey-267p15.1; wu:fa20g08; zgc:66303",
        "protein_names_uniprotkb": "Golgi resident protein GCP60; Acyl-CoA-binding domain-containing protein 3; Golgi complex-associated protein 1; Golgi phosphoprotein 1",
        "protein_names_refseq": "Golgi resident protein GCP60 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:406270)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase., [UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.uniprot.org/uniprot/A0AB32TAG3",
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        "protein_name": "TBC1 domain family member 16 isoform X1",
        "gene_name": "tbc1d16",
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        "gene_names_refseq": "fi28h02; tbc1d16; wu:fi28h02; zgc:101681",
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        "gene_name": "si:ch73-160p18.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-160p18.3",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072915",
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        "gene_names_refseq": "si:ch73-160p18.3",
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        "protein_names_refseq": "uncharacterized protein si:ch73-160p18.3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072915.1. COMPLETENESS: full length., [RefSeq]",
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    },
    {
        "uniprot_canonical_ac": "A0AB32TAN1-1",
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            {
                "id": "A0AB32TAN1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TAN1",
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        ],
        "mass": 269366.0,
        "length": 2396,
        "protein_name": "Probable helicase senataxin isoform X1",
        "gene_name": "setx",
        "organism": "Zebrafish",
        "refseq_name": "probable helicase senataxin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068072062",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072062",
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        ],
        "gene_names_uniprotkb": "setx",
        "gene_names_refseq": "setx",
        "protein_names_uniprotkb": "Probable helicase senataxin isoform X1",
        "protein_names_refseq": "probable helicase senataxin isoform X1",
        "tax_id": 7955,
        "disease": "spinocerebellar ataxia with axonal neuropathy 2 (Disease Ontology:DOID:0050755); amyotrophic lateral sclerosis type 4 (Disease Ontology:DOID:0060196)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0004386 helicase activity;GO:0003723 RNA binding;GO:0001147 transcription termination site sequence-specific DNA binding",
        "go_cellular_component": "GO:0016604 nuclear body",
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    {
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        ],
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        "protein_name": "Extracellular calcium-sensing receptor-like",
        "gene_name": "olfce2",
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        ],
        "gene_names_uniprotkb": "olfce2",
        "gene_names_refseq": "olfce2",
        "protein_names_uniprotkb": "Extracellular calcium-sensing receptor-like",
        "protein_names_refseq": "extracellular calcium-sensing receptor-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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                "url": "https://www.uniprot.org/uniprot/A0AB32TAT4",
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        ],
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        "length": 385,
        "protein_name": "Mitochondrial basic amino acids transporter",
        "gene_name": "slc25a29",
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        "refseq_name": "mitochondrial basic amino acids transporter isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068071647",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071647",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc25a29; zgc:114094",
        "gene_names_refseq": "slc25a29; zgc:114094",
        "protein_names_uniprotkb": "Mitochondrial basic amino acids transporter; Carnitine/acylcarnitine translocase-like; Mitochondrial carnitine/acylcarnitine carrier protein CACL; Mitochondrial ornithine transporter 3; Solute carrier family 25 member 29",
        "protein_names_refseq": "mitochondrial basic amino acids transporter isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0015174 basic amino acid transmembrane transporter activity",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:1990575 mitochondrial L-ornithine transmembrane transport",
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        "kg_view_protein": true
    },
    {
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                "id": "A0AB32TAT6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TAT6",
                "type": "external"
            }
        ],
        "mass": 57970.0,
        "length": 510,
        "protein_name": "S-phase kinase-associated protein 2",
        "gene_name": "skp2",
        "organism": "Zebrafish",
        "refseq_name": "S-phase kinase-associated protein 2 isoform X2",
        "refseq_ac": [
            {
                "id": "XP_068072015",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072015",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "skp2; id:ibd5121; sb:cb933; wu:fa10b08; wu:fj97b11; zgc:162950",
        "gene_names_refseq": "id:ibd5121; sb:cb933; skp2; wu:fa10b08; wu:fj97b11; zgc:162950",
        "protein_names_uniprotkb": "S-phase kinase-associated protein 2; Cyclin-A/CDK2-associated protein p45; F-box protein Skp2",
        "protein_names_refseq": "S-phase kinase-associated protein 2 isoform X2",
        "tax_id": 7955,
        "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); endometrial hyperplasia (Disease Ontology:DOID:0080365); prostate cancer (Disease Ontology:DOID:10283); prostate carcinoma (Disease Ontology:DOID:10286); breast cancer (Disease Ontology:DOID:1612); transitional cell carcinoma (Disease Ontology:DOID:2671); renal cell carcinoma (Disease Ontology:DOID:4450); lung small cell carcinoma (Disease Ontology:DOID:5409); hepatocellular carcinoma (Disease Ontology:DOID:684); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072015.1. COMPLETENESS: full length., [RefSeq]; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, NBN, FOXO1, UBP43, YTHDF2, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-dependent manner, thereby regulating cell migration. Following phosphorylation in response to DNA damage, mediates 'Lys-63'-linked ubiquitination of NBN, promoting ATM recruitment to DNA damage sites and DNA repair via homologous recombination., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0016301 kinase activity;GO:0140767 enzyme-substrate adaptor activity;GO:1990756 ubiquitin-like ligase-substrate adaptor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0019005 SCF ubiquitin ligase complex",
        "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070534 protein K63-linked ubiquitination;GO:1905168 positive regulation of double-strand break repair via homologous recombination;GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0AB32TAX7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TAX7",
                "type": "external"
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        ],
        "mass": 27565.0,
        "length": 238,
        "protein_name": "Gastrula zinc finger protein XlCGF49.1-like",
        "gene_name": "LOC101882465",
        "organism": "Zebrafish",
        "refseq_name": "gastrula zinc finger protein XlCGF49.1-like",
        "refseq_ac": [
            {
                "id": "NP_001373451",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373451",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101882465",
        "gene_names_refseq": "LOC101882465",
        "protein_names_uniprotkb": "Gastrula zinc finger protein XlCGF49.1-like",
        "protein_names_refseq": "gastrula zinc finger protein XlCGF49.1-like",
        "tax_id": 7955,
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        "pathway": " (dre:101882465)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.478932.1, SRR32588724.476753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Aug 29, 2020 this sequence version replaced XP_005164333.1., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
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            {
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        "gene_name": "LOC137488974",
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        "refseq_ac": [
            {
                "id": "XP_068072588",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072588",
                "type": "external"
            }
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        "gene_names_refseq": "LOC137488974",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Proteinase-activated receptor 1",
        "gene_name": "LOC794215",
        "organism": "Zebrafish",
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            {
                "id": "XP_068072090",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072090",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC794215",
        "gene_names_refseq": "LOC794215",
        "protein_names_uniprotkb": "Proteinase-activated receptor 1; Thrombin receptor",
        "protein_names_refseq": "proteinase-activated receptor 1-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072090.1. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
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        ],
        "mass": 41927.0,
        "length": 371,
        "protein_name": "Uncharacterized protein si:dkey-15j16.6 isoform X1",
        "gene_name": "si:dkey-15j16.6",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-15j16.6 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068071737",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071737",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-15j16.6",
        "gene_names_refseq": "si:dkey-15j16.6",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-15j16.6 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:dkey-15j16.6 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane",
        "go_biological_process": "GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway;GO:0031295 T cell costimulation;GO:0042130 negative regulation of T cell proliferation;GO:0071222 cellular response to lipopolysaccharide",
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        "kg_view_protein": true
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        "mass": 127523.0,
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        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC101883008",
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                "id": "XP_068072618",
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                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC101883008",
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        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072618.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        ],
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        "length": 1902,
        "protein_name": "Tubby-related protein 4",
        "gene_name": "tulp4b",
        "organism": "Zebrafish",
        "refseq_name": "tubby-related protein 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068070623",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070623",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "tulp4b",
        "gene_names_refseq": "tulp4b",
        "protein_names_uniprotkb": "Tubby-related protein 4; Tubby superfamily protein; Tubby-like protein 4",
        "protein_names_refseq": "tubby-related protein 4 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "length": 52,
        "protein_name": "Phospholamban",
        "gene_name": "pln2",
        "organism": "Zebrafish",
        "refseq_name": "phospholamban",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070639",
                "type": "external"
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        "gene_names_uniprotkb": "pln2",
        "gene_names_refseq": "pln2",
        "protein_names_uniprotkb": "Phospholamban",
        "protein_names_refseq": "phospholamban",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            },
            {
                "id": "1.5.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2",
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            }
        ],
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        ],
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        "protein_name": "CCHC-type domain-containing protein",
        "gene_name": "LOC137488159",
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            {
                "id": "XP_068070776",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070776",
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        "gene_names_uniprotkb": "LOC137488159",
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        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "pathway": " (dre:137488159)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068070776.1. COMPLETENESS: full length., [RefSeq]",
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    {
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            {
                "id": "A0AB32TBL0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TBL0",
                "type": "external"
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        ],
        "mass": 337178.0,
        "length": 3113,
        "protein_name": "Collagen alpha-1(XII) chain",
        "gene_name": "col12a1a",
        "organism": "Zebrafish",
        "refseq_name": "collagen alpha-1(XII) chain isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068070789",
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        ],
        "gene_names_uniprotkb": "col12a1a",
        "gene_names_refseq": "col12a1a",
        "protein_names_uniprotkb": "Collagen alpha-1(XII) chain",
        "protein_names_refseq": "collagen alpha-1(XII) chain isoform X1",
        "tax_id": 7955,
        "disease": "Ullrich congenital muscular dystrophy 2 (Disease Ontology:DOID:0060948); Bethlem myopathy 2 (Disease Ontology:DOID:0061201)",
        "pathway": " (dre:100149543)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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    {
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        ],
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        "gene_name": "LOC101883867",
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            {
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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        "protein_name": "D-galactoside-specific lectin isoform X1",
        "gene_name": "LOC137487327",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071389",
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        ],
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
        "mass": 145683.0,
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        "protein_name": "C-Jun-amino-terminal kinase-interacting protein 4",
        "gene_name": "spag9a",
        "organism": "Zebrafish",
        "refseq_name": "sperm associated antigen 9a isoform X1",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073229",
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        "gene_names_uniprotkb": "spag9a; zgc:165467",
        "gene_names_refseq": "spag9a; zgc:165467",
        "protein_names_uniprotkb": "C-Jun-amino-terminal kinase-interacting protein 4; JNK-associated leucine-zipper protein; Mitogen-activated protein kinase 8-interacting protein 4; Sperm-associated antigen 9",
        "protein_names_refseq": "sperm associated antigen 9a isoform X1",
        "tax_id": 7955,
        "disease": "endometrial cancer (Disease Ontology:DOID:1380); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684)",
        "pathway": " (dre:558833);  (R-DRE-525793)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "gene_name": "c19h1orf216",
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        "refseq_name": "UPF0500 protein C1orf216 homolog",
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        "gene_name": "col6a4a",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070384",
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        "gene_names_refseq": "col6a4a",
        "protein_names_uniprotkb": "Collagen alpha-6(VI) chain",
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        "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity",
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        "protein_names_uniprotkb": "Synaptotagmin-14b isoform X1",
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        "disease": "autosomal recessive spinocerebellar ataxia 11 (Disease Ontology:DOID:0080063)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
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        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TC24-1",
        "uniprot_id": [
            {
                "id": "A0AB32TC24_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TC24",
                "type": "external"
            }
        ],
        "mass": 56078.0,
        "length": 458,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC137488218",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_068070942",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070942",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137488218",
        "gene_names_refseq": "LOC137488218",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137488218)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AB32TC24-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TC44-1",
        "uniprot_id": [
            {
                "id": "A0AB32TC44_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TC44",
                "type": "external"
            }
        ],
        "mass": 42670.0,
        "length": 361,
        "protein_name": "Guanine nucleotide-binding protein subunit alpha",
        "gene_name": "gna15.3",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: guanine nucleotide-binding protein subunit alpha-14",
        "refseq_ac": [
            {
                "id": "XP_068072560",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072560",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gna15.3",
        "gene_names_refseq": "gna15.3",
        "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit alpha",
        "protein_names_refseq": "LOW QUALITY PROTEIN: guanine nucleotide-binding protein subunit alpha-14",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100034592)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts                 :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072560.1. COMPLETENESS: full length., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding",
        "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TC53-1",
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            {
                "id": "A0AB32TC53_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TC53",
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        ],
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        "length": 883,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101882393",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068070972",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070972",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101882393",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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    {
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        "protein_name": "Uncharacterized protein si:ch211-263m18.4",
        "gene_name": "si:ch211-263m18.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-263m18.4",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072246",
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        "protein_names_refseq": "uncharacterized protein si:ch211-263m18.4",
        "tax_id": 7955,
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        "predicted_glycosites": 0,
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    },
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        "uniprot_id": [
            {
                "id": "A0AB32TC69_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TC69",
                "type": "external"
            }
        ],
        "mass": 156432.0,
        "length": 1394,
        "protein_name": "Nuclear pore complex protein Nup160",
        "gene_name": "nup160",
        "organism": "Zebrafish",
        "refseq_name": "nuclear pore complex protein Nup160",
        "refseq_ac": [
            {
                "id": "NP_001410773",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410773",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nup160; zgc:66306",
        "gene_names_refseq": "nup160; zgc:66306",
        "protein_names_uniprotkb": "Nuclear pore complex protein Nup160",
        "protein_names_refseq": "nuclear pore complex protein Nup160",
        "tax_id": 7955,
        "disease": "nephrotic syndrome type 19 (Disease Ontology:DOID:0080394)",
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        "publication_id_list": "18307296;26469318",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01000540.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0005643 nuclear pore",
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        ],
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        "protein_name": "Somatostatin receptor type 3",
        "gene_name": "LOC137489127",
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        "protein_names_uniprotkb": "Somatostatin receptor type 3",
        "protein_names_refseq": "somatostatin receptor type 3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "gene_name": "LOC137489076",
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        "protein_names_refseq": "sushi, nidogen and EGF-like domain-containing protein 1",
        "tax_id": 7955,
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        "gene_name": "LOC797394",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072496.1. COMPLETENESS: full length., [RefSeq]",
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            {
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        "length": 2176,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072948.1. COMPLETENESS: full length., [RefSeq]; May be involved in neuronal migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Extracellular calcium-sensing receptor",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "organism": "Zebrafish",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072736",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072736.1. COMPLETENESS: full length., [RefSeq]",
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                "id": "XP_068071806",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073219",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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            },
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27",
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        "protein_names_refseq": "V-set domain-containing T-cell activation inhibitor 1-like",
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            {
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "disease": "breast cancer (Disease Ontology:DOID:1612); breast adenocarcinoma (Disease Ontology:DOID:3458)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068069859.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
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            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
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            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
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            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
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                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
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            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
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            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane",
        "go_biological_process": "GO:0007265 Ras protein signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32T8U5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
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            {
                "id": "A0AB32T8Z7_DANRE",
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        ],
        "mass": 39809.0,
        "length": 343,
        "protein_name": "Calcium binding protein 39, like 1 isoform X1",
        "gene_name": "cab39l1",
        "organism": "Zebrafish",
        "refseq_name": "calcium binding protein 39, like 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068069286",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069286",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "cab39l1; cab39; wu:fb72b01; wu:fi37c08; zgc:55451",
        "gene_names_refseq": "cab39l1; cab39; wu:fb72b01; wu:fi37c08; zgc:55451",
        "protein_names_uniprotkb": "Calcium binding protein 39, like 1 isoform X1",
        "protein_names_refseq": "calcium binding protein 39, like 1 isoform X1",
        "tax_id": 7955,
        "disease": "cancer (Disease Ontology:DOID:162)",
        "pathway": " (dre:406822)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "gene_name": "rap1gap2b",
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            {
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            }
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068074400.1. COMPLETENESS: full length., [RefSeq]",
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            {
                "id": "XP_068072542",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072542",
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        "gene_names_uniprotkb": "LOC100151486",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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            {
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        ],
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        "length": 6058,
        "protein_name": "Uncharacterized protein muc5.2",
        "gene_name": "muc5.2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein muc5.2",
        "refseq_ac": [
            {
                "id": "XP_068073595",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073595",
                "type": "external"
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        ],
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        "gene_names_refseq": "muc5.2",
        "protein_names_uniprotkb": "Uncharacterized protein muc5.2",
        "protein_names_refseq": "uncharacterized protein muc5.2",
        "tax_id": 7955,
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        "pathway": " (dre:572172)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068073595.1. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005179 hormone activity",
        "go_cellular_component": "GO:0005576 extracellular region",
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0AB32TF38",
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        ],
        "mass": 221699.0,
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        "protein_name": "Myosin heavy chain, fast skeletal muscle",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073792927",
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        ],
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        "gene_names_refseq": "zgc:66156",
        "protein_names_uniprotkb": "Myosin heavy chain, fast skeletal muscle",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58IFB5",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0003774 cytoskeletal motor activity",
        "go_cellular_component": "GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016459 myosin complex",
        "go_biological_process": "GO:0048731 system development",
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        "kg_view_protein": true
    },
    {
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                "url": "https://www.uniprot.org/uniprot/A0AB32TF53",
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        ],
        "mass": 66558.0,
        "length": 578,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC100150670",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068072624",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072624",
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            }
        ],
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        "gene_names_refseq": "LOC100150670",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription",
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    },
    {
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        ],
        "mass": 16789.0,
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        "protein_name": "Ras-related C3 botulinum toxin substrate 1-like; Ras-related C3 botulinum toxin substrate 1b isoform X1",
        "gene_name": "LOC100537765",
        "organism": "Zebrafish",
        "refseq_name": "ras-related C3 botulinum toxin substrate 1-like",
        "refseq_ac": [
            {
                "id": "XP_068073999",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073999",
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            }
        ],
        "gene_names_uniprotkb": "LOC100537765; rac1b; zgc:136799",
        "gene_names_refseq": "LOC100537765",
        "protein_names_uniprotkb": "Ras-related C3 botulinum toxin substrate 1-like; Ras-related C3 botulinum toxin substrate 1b isoform X1",
        "protein_names_refseq": "ras-related C3 botulinum toxin substrate 1-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
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        ],
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        "gene_name": "LOC100535941",
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        "refseq_name": "uncharacterized LOC100535941",
        "refseq_ac": [
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        "gene_names_refseq": "LOC100535941",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized LOC100535941; zinc finger protein 420",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100535941)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.1507945.1, SRR26395012.1545474.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Aug 13, 2025 this sequence version replaced XP_068072617.2., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "length": 250,
        "protein_name": "Immunoglobulin domain-containing protein",
        "gene_name": "LOC137489000",
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        "refseq_ac": [
            {
                "id": "XP_068072684",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072684",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC137489000",
        "gene_names_refseq": "LOC137489000",
        "protein_names_uniprotkb": "Immunoglobulin domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072684.1. COMPLETENESS: full length., [RefSeq]",
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        ],
        "mass": 44175.0,
        "length": 393,
        "protein_name": "Neuroplastin",
        "gene_name": "nptna",
        "organism": "Zebrafish",
        "refseq_name": "neuroplastin a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068073432",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073432",
                "type": "external"
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        "gene_names_refseq": "nptna; sb:cb578; wu:fj19g07; zgc:162565",
        "protein_names_uniprotkb": "Neuroplastin; Stromal cell-derived receptor 1",
        "protein_names_refseq": "neuroplastin a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068073432.1. COMPLETENESS: full length., [RefSeq]; Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0030425 dendrite",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0007399 nervous system development;GO:0048545 response to steroid hormone;GO:0050804 modulation of chemical synaptic transmission;GO:0051239 regulation of multicellular organismal process",
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        "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1",
        "gene_name": "LOC137489911",
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        "refseq_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068074029",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068074029",
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        "gene_names_uniprotkb": "LOC137489911",
        "gene_names_refseq": "LOC137489911",
        "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 3 isoform X1",
        "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 3 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein isoform X3",
        "gene_name": "LOC566710",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072647",
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        "gene_names_uniprotkb": "LOC566710",
        "gene_names_refseq": "LOC566710",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X3",
        "protein_names_refseq": "uncharacterized protein isoform X3",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072647.1. COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        "mass": 338421.0,
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        "gene_name": "LOC100007727",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068074595",
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        "protein_names_uniprotkb": "GTPase IMAP family member 8; Immune-associated nucleotide-binding protein 9",
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            }
        ],
        "gene_names_uniprotkb": "LOC110438590",
        "gene_names_refseq": "LOC110438590",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM35-like",
        "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM35-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110438590)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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    },
    {
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            {
                "id": "A0AB32TFT4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TFT4",
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        ],
        "mass": 57992.0,
        "length": 508,
        "protein_name": "procollagen-proline 4-dioxygenase",
        "gene_name": "LOC110438249",
        "organism": "Zebrafish",
        "refseq_name": "prolyl 4-hydroxylase subunit alpha-2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068072282",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072282",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110438249",
        "gene_names_refseq": "LOC110438249",
        "protein_names_uniprotkb": "procollagen-proline 4-dioxygenase; 1.14.11.2",
        "protein_names_refseq": "prolyl 4-hydroxylase subunit alpha-2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110438249)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072282.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0005506 iron ion binding;GO:0031418 L-ascorbic acid binding;GO:0004656 procollagen-proline 4-dioxygenase activity",
        "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen",
        "go_biological_process": "",
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    },
    {
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        ],
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            {
                "id": "XP_073792139",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073792139",
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            }
        ],
        "gene_names_uniprotkb": "LOC137487250",
        "gene_names_refseq": "LOC137487250",
        "protein_names_uniprotkb": "RRM domain-containing protein",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068074760",
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            }
        ],
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        "gene_names_refseq": "blacat1",
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        "predicted_glycosites": 0,
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        ],
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        ],
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        "protein_names_uniprotkb": "Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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            }
        ],
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        ],
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        ],
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        "predicted_glycosites": 0,
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        "protein_names_refseq": "REC8 meiotic recombination protein b isoform X1",
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        "gene_name": "a2m3f",
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        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430386",
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        "gene_names_uniprotkb": "a2m3f",
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        "protein_names_uniprotkb": "Alpha-2-macroglobulin-like protein 1",
        "protein_names_refseq": "alpha-2-macroglobulin 3, member f precursor",
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        "protein_name": "Dentin sialophosphoprotein-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075134.1. COMPLETENESS: full length., [RefSeq]",
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        "mass": 68726.0,
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        "protein_name": "C2H2-type domain-containing protein",
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        "protein_name": "Multiple epidermal growth factor-like domains protein 6 isoform X1",
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        "gene_names_uniprotkb": "megf6a",
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        "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 6 isoform X1",
        "protein_names_refseq": "multiple epidermal growth factor-like domains protein 6 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075149.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein si:dkey-1b17.1",
        "gene_name": "si:dkey-1b17.1",
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        "refseq_name": "uncharacterized protein si:dkey-1b17.1",
        "refseq_ac": [
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        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-1b17.1",
        "protein_names_refseq": "uncharacterized protein si:dkey-1b17.1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32TH34-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TH35-1",
        "uniprot_id": [
            {
                "id": "A0AB32TH35_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TH35",
                "type": "external"
            }
        ],
        "mass": 34964.0,
        "length": 310,
        "protein_name": "Ig-like domain-containing protein",
        "gene_name": "LOC137489053",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_068072730",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072730",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137489053",
        "gene_names_refseq": "LOC137489053",
        "protein_names_uniprotkb": "Ig-like domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137489053)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072730.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32TH35-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TH50-1",
        "uniprot_id": [
            {
                "id": "A0AB32TH50_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TH50",
                "type": "external"
            }
        ],
        "mass": 40927.0,
        "length": 341,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137489752",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068073883",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073883",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137489752",
        "gene_names_refseq": "LOC137489752",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137489752)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068073883.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32TH50-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TH53-1",
        "uniprot_id": [
            {
                "id": "A0AB32TH53_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TH53",
                "type": "external"
            }
        ],
        "mass": 23994.0,
        "length": 210,
        "protein_name": "Uncharacterized protein LOC100005854; Uncharacterized protein isoform X1",
        "gene_name": "zgc:194242",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC100005854",
        "refseq_ac": [
            {
                "id": "NP_001122287",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122287",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "zgc:194242",
        "gene_names_refseq": "zgc:194242",
        "protein_names_uniprotkb": "Uncharacterized protein LOC100005854; Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein LOC100005854",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100005854)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC162754.1, CN174667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505379 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from BC162754.1. On Jul 31, 2008 this sequence version replaced XP_001340179.2., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0016740 transferase activity;GO:0003838 sterol 24-C-methyltransferase activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum",
        "go_biological_process": "GO:0016126 sterol biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0AB32TH53-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TH67-1",
        "uniprot_id": [
            {
                "id": "IFNU_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TH67",
                "type": "external"
            }
        ],
        "mass": 19039.0,
        "length": 163,
        "protein_name": "Interferon upsilon",
        "gene_name": "ifnu",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein ifnu",
        "refseq_ac": [
            {
                "id": "XP_068073389",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073389",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ifnu",
        "gene_names_refseq": "ifnu",
        "protein_names_uniprotkb": "Interferon upsilon; IFN-u",
        "protein_names_refseq": "uncharacterized protein ifnu",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137489279)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23594743;35194032",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytokine with antiviral activity that is produced by host cells in response to viral infection and acts as a regulator of immune defense through induction of interferon-stimulated genes and modulation of signaling pathways (PubMed:35194032). IL10R2/CRBF4 and IFNUR1/CRBF12 form the dimeric receptor for this cytokine (PubMed:35194032)., [UniProtKB, PubMed]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 1,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0140374 antiviral innate immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0AB32TH67-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AB32THB0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32THB0",
                "type": "external"
            }
        ],
        "mass": 23315.0,
        "length": 214,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC103909452",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_068072280",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072280",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC103909452",
        "gene_names_refseq": "LOC103909452",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:103909452)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_c_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32THB0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32THC7-1",
        "uniprot_id": [
            {
                "id": "A0AB32THC7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32THC7",
                "type": "external"
            }
        ],
        "mass": 20719.0,
        "length": 178,
        "protein_name": "Troponin I type 2a (Skeletal, fast), tandem duplicate 2",
        "gene_name": "tnni2a.2",
        "organism": "Zebrafish",
        "refseq_name": "troponin I type 2a (skeletal, fast), tandem duplicate 2",
        "refseq_ac": [
            {
                "id": "NP_001417878",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417878",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tnni2a.2; Tnni2; zgc:56294",
        "gene_names_refseq": "Tnni2; tnni2a.2; zgc:56294",
        "protein_names_uniprotkb": "Troponin I type 2a (Skeletal, fast), tandem duplicate 2",
        "protein_names_refseq": "tropI-1b; troponin I type 2a (skeletal, fast), tandem duplicate 2; troponin I, skeletal, fast 2a, tandem duplicate 2; troponin I, skeletal, fast 2a.2",
        "tax_id": 7955,
        "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); cardiomyopathy (Disease Ontology:DOID:0050700); stroke (Disease Ontology:DOID:0051061); arthrogryposis multiplex congenita (Disease Ontology:DOID:0080954); hypertrophic cardiomyopathy 7 (Disease Ontology:DOID:0110313); dilated cardiomyopathy 1FF (Disease Ontology:DOID:0110459); dilated cardiomyopathy 2A (Disease Ontology:DOID:0110460); familial restrictive cardiomyopathy 1 (Disease Ontology:DOID:0111425); distal arthrogryposis type 2B1 (Disease Ontology:DOID:0111600); heart disease (Disease Ontology:DOID:114); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); adenocarcinoma (Disease Ontology:DOID:299); coronary artery disease (Disease Ontology:DOID:3393); restrictive cardiomyopathy (Disease Ontology:DOID:397)",
        "pathway": " (dre:394068)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "18253507;25583992;26979795;27189481;34016526",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041573.1, SRR32588725.48225344.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1., [RefSeq]; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 15,
        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding",
        "go_cellular_component": "GO:0005861 troponin complex",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0AB32THC7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AB32THP1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32THP1",
                "type": "external"
            }
        ],
        "mass": 62659.0,
        "length": 540,
        "protein_name": "Tripartite motif-containing protein 16 isoform X1",
        "gene_name": "ftr59",
        "organism": "Zebrafish",
        "refseq_name": "tripartite motif-containing protein 16 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068072958",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072958",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ftr59",
        "gene_names_refseq": "ftr59",
        "protein_names_uniprotkb": "Tripartite motif-containing protein 16 isoform X1",
        "protein_names_refseq": "tripartite motif-containing protein 16 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding",
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        "mass": 36875.0,
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC137490694",
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        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
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                "id": "XP_068075390",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075390",
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        ],
        "gene_names_uniprotkb": "LOC137490694",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0AB32THR3",
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        ],
        "mass": 61906.0,
        "length": 555,
        "protein_name": "Copine-8",
        "gene_name": "cpne9",
        "organism": "Zebrafish",
        "refseq_name": "copine-9 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068073032",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073032",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cpne9",
        "gene_names_refseq": "cpne9",
        "protein_names_uniprotkb": "Copine-8; Copine VIII",
        "protein_names_refseq": "copine-9 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101886563)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding",
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        ],
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        "protein_name": "Protein shisa-like-1a",
        "gene_name": "shisal1b",
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        "tax_id": 7955,
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        "gene_name": "LOC137490522",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068074929",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137490522",
        "gene_names_refseq": "LOC137490522",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068074929.1. COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "smc1b",
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        "refseq_name": "structural maintenance of chromosomes protein 1B",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073614",
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        ],
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075033.1. COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068074437.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Box C/D snoRNA protein 1",
        "gene_name": "znhit6",
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        "go_molecular_function": "GO:0008832 dGTPase activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0051607 defense response to virus;GO:0006203 dGTP catabolic process;GO:0045088 regulation of innate immune response",
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        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0AB32TKQ9",
                "type": "external"
            }
        ],
        "mass": 54485.0,
        "length": 476,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC110439424",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized LOC110439424",
        "refseq_ac": [
            {
                "id": "NP_001428717",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428717",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC110439424",
        "gene_names_refseq": "LOC110439424",
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        "protein_names_refseq": "uncharacterized LOC110439424",
        "tax_id": 7955,
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        "pathway": " (dre:110439424)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.8708297.1, SRR32588722.28138307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06645146 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jul 2, 2025 this sequence version replaced XP_068075934.1., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_biological_process": "GO:0006351 DNA-templated transcription",
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    },
    {
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        ],
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        "length": 1965,
        "protein_name": "LIM and calponin homology domains-containing protein 1a isoform X1",
        "gene_name": "limch1a",
        "organism": "Zebrafish",
        "refseq_name": "LIM and calponin homology domains-containing protein 1a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068076070",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068076070",
                "type": "external"
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        ],
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        "gene_names_refseq": "limch1a; si:ch211-157h5.2",
        "protein_names_uniprotkb": "LIM and calponin homology domains-containing protein 1a isoform X1",
        "protein_names_refseq": "LIM and calponin homology domains-containing protein 1a isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:561940)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068076070.1. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075293",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 8,
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        "protein_name": "DNA-binding protein RFX7 isoform X1",
        "gene_name": "rfx7b",
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        "refseq_name": "DNA-binding protein RFX7 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_003201650",
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        ],
        "gene_names_uniprotkb": "rfx7b",
        "gene_names_refseq": "rfx7b",
        "protein_names_uniprotkb": "DNA-binding protein RFX7 isoform X1",
        "protein_names_refseq": "DNA-binding protein RFX7 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003201650.1. COMPLETENESS: full length., [RefSeq]",
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        ],
        "mass": 33598.0,
        "length": 297,
        "protein_name": "Uncharacterized protein si:dkey-19b23.7 isoform X1",
        "gene_name": "si:dkey-19b23.7",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-19b23.7 isoform X1",
        "refseq_ac": [
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        "tax_id": 7955,
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        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "kg_view_protein": true
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            {
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                "type": "external"
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        ],
        "mass": 54264.0,
        "length": 471,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "fc30c06",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075624",
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        "gene_names_refseq": "fc30c06; wu:fc30c06",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        ],
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "gene_name": "zgc:173720",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.1418327.1, SRR26395012.894741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505387, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Aug 18, 2023 this sequence version replaced NP_001103210.1., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "gene_names_refseq": "si:dkey-57c22.3; zgc:174650",
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        "disease": "specific developmental disorder (Disease Ontology:DOID:0060038); autism spectrum disorder (Disease Ontology:DOID:0060041); speech-language disorder-1 (Disease Ontology:DOID:0111275); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); autistic disorder (Disease Ontology:DOID:12849); major depressive disorder (Disease Ontology:DOID:1470); articulation disorder (Disease Ontology:DOID:4186); dyslexia (Disease Ontology:DOID:4428); schizophrenia (Disease Ontology:DOID:5419); language disorder (Disease Ontology:DOID:93)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 281,
        "protein_name": "Troponin T2e, cardiac isoform X1",
        "gene_name": "tnnt2e",
        "organism": "Zebrafish",
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        "refseq_ac": [
            {
                "id": "XP_068075741",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075741",
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        ],
        "gene_names_uniprotkb": "tnnt2e; si:ch211-136g2.1",
        "gene_names_refseq": "si:ch211-136g2.1; tnnt2e",
        "protein_names_uniprotkb": "Troponin T2e, cardiac isoform X1",
        "protein_names_refseq": "troponin T2e, cardiac isoform X1",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); hypertrophic cardiomyopathy 2 (Disease Ontology:DOID:0110308); dilated cardiomyopathy 1D (Disease Ontology:DOID:0110426); nemaline myopathy (Disease Ontology:DOID:3191)",
        "pathway": " (dre:556703)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "gene_names_refseq": "LOC137491040",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068076116",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068076685",
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        ],
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        "protein_names_uniprotkb": "Spexin prohormone 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017211746.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Neurotensin/neuromedin N",
        "gene_name": "nts",
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        "disease": "nicotine dependence (Disease Ontology:DOID:0050742); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); sciatic neuropathy (Disease Ontology:DOID:11446); depressive disorder (Disease Ontology:DOID:1596)",
        "pathway": " (dre:101884890);  (R-DRE-375276);  (R-DRE-416476)",
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        "gene_name": "igf2bp2a",
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        "protein_names_uniprotkb": "Insulin-like growth factor 2 mRNA-binding protein 2a",
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        "tax_id": 7955,
        "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
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        "publication_count": 7,
        "publication_id_list": "18803835;21048110;23451191;26325373;26469318;26963759;34352271",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: DQ998838.1, EU296401.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ998838.1. On Aug 9, 2008 this sequence version replaced NP_001108030.1., [RefSeq]; IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish., [RefSeq, PubMed]",
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        "missing_score": 10000,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NFP1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule",
        "go_biological_process": "GO:0070934 CRD-mediated mRNA stabilization;GO:0006417 regulation of translation;GO:0007399 nervous system development;GO:0051028 mRNA transport",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0G2KDL6-1",
        "uniprot_id": [
            {
                "id": "A0A0G2KDL6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2KDL6",
                "type": "external"
            }
        ],
        "mass": 123402.0,
        "length": 1122,
        "protein_name": "Photoreceptor cilium actin regulator",
        "gene_name": "pcare1",
        "organism": "Zebrafish",
        "refseq_name": "photoreceptor cilium actin regulator",
        "refseq_ac": [
            {
                "id": "XP_003200429",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200429",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pcare1",
        "gene_names_refseq": "pcare1",
        "protein_names_uniprotkb": "Photoreceptor cilium actin regulator",
        "protein_names_refseq": "photoreceptor cilium actin regulator",
        "tax_id": 7955,
        "disease": "retinitis pigmentosa 54 (Disease Ontology:DOID:0110364)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200429.1. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "go_biological_process": "GO:0060041 retina development in camera-type eye;GO:0042461 photoreceptor cell development;GO:0021549 cerebellum development;GO:0050908 detection of light stimulus involved in visual perception;GO:0060026 convergent extension",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0G2KGF4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2KGF4",
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            }
        ],
        "mass": 128435.0,
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        "protein_name": "Transmembrane protein 132D",
        "gene_name": "LOC100332191",
        "organism": "Zebrafish",
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        "refseq_ac": [
            {
                "id": "XP_021334148",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334148",
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            }
        ],
        "gene_names_uniprotkb": "LOC100332191",
        "gene_names_refseq": "LOC100332191",
        "protein_names_uniprotkb": "Transmembrane protein 132D",
        "protein_names_refseq": "transmembrane protein 132D",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0G2KGX6-1",
        "uniprot_id": [
            {
                "id": "A0A0G2KGX6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2KGX6",
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            }
        ],
        "mass": 48237.0,
        "length": 420,
        "protein_name": "Uncharacterized protein znf1040",
        "gene_name": "znf1040",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein znf1040",
        "refseq_ac": [
            {
                "id": "XP_017211075",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211075",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "znf1040",
        "gene_names_refseq": "znf1040",
        "protein_names_uniprotkb": "Uncharacterized protein znf1040",
        "protein_names_refseq": "uncharacterized protein znf1040",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101884948)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M6Z6D2;A0AC58JE25;A0AC58JE28;A0AC58JE35",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KH34",
                "type": "external"
            }
        ],
        "mass": 28320.0,
        "length": 251,
        "protein_name": "T-cell leukemia homeobox protein 3",
        "gene_name": "tlx3a",
        "organism": "Zebrafish",
        "refseq_name": "T-cell leukemia homeobox protein 3",
        "refseq_ac": [
            {
                "id": "XP_003199819",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199819",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tlx3a",
        "gene_names_refseq": "tlx3a",
        "protein_names_uniprotkb": "T-cell leukemia homeobox protein 3",
        "protein_names_refseq": "T-cell leukemia homeobox protein 3",
        "tax_id": 7955,
        "disease": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048513 animal organ development",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KI21",
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        ],
        "mass": 33768.0,
        "length": 292,
        "protein_name": "Uncharacterized protein LOC567472",
        "gene_name": "LOC567472",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC567472 precursor",
        "refseq_ac": [
            {
                "id": "NP_001122013",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122013",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC567472",
        "gene_names_refseq": "LOC567472",
        "protein_names_uniprotkb": "Uncharacterized protein LOC567472",
        "protein_names_refseq": "uncharacterized protein LOC567472 precursor",
        "tax_id": 7955,
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        "pathway": " (dre:567472)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588720.2901980.1, ERR6511329.1265835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Nov 25, 2025 this sequence version replaced NP_001122013.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NHN8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005125 cytokine activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space",
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        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KIH5",
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            }
        ],
        "mass": 39240.0,
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        "protein_name": "Major histocompatibility complex class I LLA isoform X1; Major histocompatibility complex class I LLA precursor",
        "gene_name": "mhc1lla",
        "organism": "Zebrafish",
        "refseq_name": "major histocompatibility complex class I LLA precursor",
        "refseq_ac": [
            {
                "id": "NP_001314818",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314818",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mhc1lla; si:dkey-52p2.4",
        "gene_names_refseq": "mhc1lla; si:dkey-52p2.4",
        "protein_names_uniprotkb": "Major histocompatibility complex class I LLA isoform X1; Major histocompatibility complex class I LLA precursor",
        "protein_names_refseq": "major histocompatibility complex class I LLA precursor; zinc-alpha-2-glycoprotein-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100536492);  (R-DRE-1236974);  (R-DRE-1236977);  (R-DRE-6798695);  (R-DRE-917977);  (R-DRE-983170)",
        "pathway_count": 6,
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        "publication_id_list": "24631581;30290758;37179373",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.26644087.1, SRR32588722.18234906.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA708836, SAMN06350655 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On May 27, 2016 this sequence version replaced XP_009296130.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane",
        "go_biological_process": "GO:0006955 immune response",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0G2KIS6-1",
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            {
                "id": "A0A0G2KIS6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2KIS6",
                "type": "external"
            }
        ],
        "mass": 50733.0,
        "length": 455,
        "protein_name": "Histamine H3 receptor",
        "gene_name": "LOC100334962",
        "organism": "Zebrafish",
        "refseq_name": "histamine H3 receptor",
        "refseq_ac": [
            {
                "id": "XP_003200969",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200969",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100334962",
        "gene_names_refseq": "LOC100334962",
        "protein_names_uniprotkb": "Histamine H3 receptor",
        "protein_names_refseq": "histamine H3 receptor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100334962);  (R-DRE-390650);  (R-DRE-418594)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0030594 neurotransmitter receptor activity;GO:0004969 histamine receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse",
        "go_biological_process": "GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0G2KJW7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2KJW7",
                "type": "external"
            }
        ],
        "mass": 35425.0,
        "length": 317,
        "protein_name": "folate gamma-glutamyl hydrolase",
        "gene_name": "LOC553228",
        "organism": "Zebrafish",
        "refseq_name": "gamma-glutamyl hydrolase precursor",
        "refseq_ac": [
            {
                "id": "NP_001243151",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243151",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC553228",
        "gene_names_refseq": "LOC553228",
        "protein_names_uniprotkb": "folate gamma-glutamyl hydrolase; 3.4.19.9",
        "protein_names_refseq": "gamma-glutamyl hydrolase precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:553228)",
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        "publication_id_list": "12477932",
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        "secondary_ac_list": "A0A8M1NYZ6",
        "ec_number_list": [
            {
                "id": "3.4.19.9",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.9",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0034722 gamma-glutamyl-peptidase activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005773 vacuole",
        "go_biological_process": "GO:0046900 tetrahydrofolylpolyglutamate metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0G2KKC2-1",
        "uniprot_id": [
            {
                "id": "A0A0G2KKC2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2KKC2",
                "type": "external"
            }
        ],
        "mass": 100203.0,
        "length": 890,
        "protein_name": "Metal transporter",
        "gene_name": "cnnm1",
        "organism": "Zebrafish",
        "refseq_name": "metal transporter CNNM1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001315457",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315457",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cnnm1; si:dkeyp-22h2.1",
        "gene_names_refseq": "cnnm1; si:dkeyp-22h2.1",
        "protein_names_uniprotkb": "Metal transporter",
        "protein_names_refseq": "metal transporter CNNM1 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:562504)",
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        "publication_id_list": "27189481;30252882;38798028",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01023543.1, SRR32588718.43655692.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 25, 2025 this sequence version replaced NP_001315457.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Metal transporter., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P517",
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        "go_molecular_function": "GO:0022857 transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0010960 magnesium ion homeostasis",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0G2KKC2-1",
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KLU8",
                "type": "external"
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        ],
        "mass": 33091.0,
        "length": 301,
        "protein_name": "Mitochondrial basic amino acids transporter",
        "gene_name": "slc25a29l",
        "organism": "Zebrafish",
        "refseq_name": "mitochondrial basic amino acids transporter",
        "refseq_ac": [
            {
                "id": "XP_002665132",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665132",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc25a29l",
        "gene_names_refseq": "slc25a29l",
        "protein_names_uniprotkb": "Mitochondrial basic amino acids transporter; Carnitine/acylcarnitine translocase-like; Mitochondrial carnitine/acylcarnitine carrier protein CACL; Mitochondrial ornithine transporter 3; Solute carrier family 25 member 29",
        "protein_names_refseq": "mitochondrial basic amino acids transporter",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100329459)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002665132.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M1RRK0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005289 high-affinity L-arginine transmembrane transporter activity;GO:0005292 high-affinity lysine transmembrane transporter activity",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:1990575 mitochondrial L-ornithine transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0G2KLU8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KM47",
                "type": "external"
            }
        ],
        "mass": 10511.0,
        "length": 96,
        "protein_name": "C-X-C motif chemokine 11-6-like",
        "gene_name": "cxcl11.4",
        "organism": "Zebrafish",
        "refseq_name": "C-X-C motif chemokine 11-6-like",
        "refseq_ac": [
            {
                "id": "XP_696046",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696046",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "cxcl11.4",
        "gene_names_refseq": "cxcl11.4",
        "protein_names_uniprotkb": "C-X-C motif chemokine 11-6-like",
        "protein_names_refseq": "C-X-C motif chemokine 11-6-like",
        "tax_id": 7955,
        "disease": "pulmonary sarcoidosis (Disease Ontology:DOID:13406); bronchiolitis obliterans (Disease Ontology:DOID:2799); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
        "pathway": " (dre:567656)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8N7UTC7",
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        "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0006952 defense response;GO:0006955 immune response",
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        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Embryonal Fyn-associated substrate",
        "gene_name": "efs",
        "organism": "Zebrafish",
        "refseq_name": "embryonal Fyn-associated substrate",
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        "gene_names_refseq": "efs; fb77c11; wu:fb77c11",
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        "protein_names_refseq": "embryonal Fyn-associated substrate",
        "tax_id": 7955,
        "disease": "Crohn's disease (Disease Ontology:DOID:8778)",
        "pathway": " (dre:100333297)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01017534.1, SRR26395062.553041.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 4, 2016 this sequence version replaced XP_002662876.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        ],
        "mass": 90944.0,
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        "protein_name": "Low-density lipoprotein receptor-related protein 3 precursor",
        "gene_name": "lrp3",
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            {
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        "gene_names_refseq": "lrp3; zgc:195027",
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        "protein_names_refseq": "low-density lipoprotein receptor-related protein 3 precursor",
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        "pathway": " (dre:100170796)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC163507.1, SRR32588731.1397900.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476757, SAMEA4476762 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 21, 2024 this sequence version replaced NP_001124106.1., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_biological_process": "GO:0006897 endocytosis",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KWZ2",
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        ],
        "mass": 12962.0,
        "length": 121,
        "protein_name": "C-X-C motif chemokine 11-6-like",
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        "organism": "Zebrafish",
        "refseq_name": "C-X-C motif chemokine 11-6-like",
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        "gene_names_uniprotkb": "cxcl11.3",
        "gene_names_refseq": "cxcl11.3",
        "protein_names_uniprotkb": "C-X-C motif chemokine 11-6-like",
        "protein_names_refseq": "C-X-C motif chemokine 11-6-like",
        "tax_id": 7955,
        "disease": "pulmonary sarcoidosis (Disease Ontology:DOID:13406); bronchiolitis obliterans (Disease Ontology:DOID:2799); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002662102.2. COMPLETENESS: full length., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2KYC0",
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        ],
        "mass": 80263.0,
        "length": 726,
        "protein_name": "Cytoplasmic polyadenylation element-binding protein 4b",
        "gene_name": "cpeb4b",
        "organism": "Zebrafish",
        "refseq_name": "cytoplasmic polyadenylation element-binding protein 4b",
        "refseq_ac": [
            {
                "id": "NP_001338642",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338642",
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        "gene_names_uniprotkb": "cpeb4b",
        "gene_names_refseq": "cpeb4b",
        "protein_names_uniprotkb": "Cytoplasmic polyadenylation element-binding protein 4b",
        "protein_names_refseq": "cytoplasmic polyadenylation element binding protein 4-like; cytoplasmic polyadenylation element-binding protein 4b",
        "tax_id": 7955,
        "disease": "portal hypertension (Disease Ontology:DOID:10762); primary biliary cholangitis (Disease Ontology:DOID:12236); liver cirrhosis (Disease Ontology:DOID:5082)",
        "pathway": " (dre:100333151)",
        "pathway_count": 1,
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        "publication_id_list": "27189481;28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01018658.1, SRR32588728.3642639.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1, EH436310.1, EH454853.1, EH435528.1, EH580807.1 and EH455067.1. On May 23, 2017 this sequence version replaced XP_009293951.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 1,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0008135 translation factor activity, RNA binding;GO:0043022 ribosome binding;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045202 synapse;GO:0043005 neuron projection",
        "go_biological_process": "GO:2000766 negative regulation of cytoplasmic translation",
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        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0G2L0J2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2L0J2",
                "type": "external"
            }
        ],
        "mass": 22901.0,
        "length": 199,
        "protein_name": "5-formyltetrahydrofolate cyclo-ligase",
        "gene_name": "mthfs",
        "organism": "Zebrafish",
        "refseq_name": "5-formyltetrahydrofolate cyclo-ligase",
        "refseq_ac": [
            {
                "id": "NP_001373342",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373342",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mthfs",
        "gene_names_refseq": "mthfs",
        "protein_names_uniprotkb": "5-formyltetrahydrofolate cyclo-ligase; 6.3.3.2",
        "protein_names_refseq": "5-formyltetrahydrofolate cyclo-ligase",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100332843);  (R-DRE-196757)",
        "pathway_count": 2,
        "publication_count": 1,
        "publication_id_list": "21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01017407.1, GDQH01022239.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505380, SAMEA4476736 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 21, 2020 this sequence version replaced XP_002662791.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "secondary_ac_list": "A0A8M6Z7S3",
        "ec_number_list": [
            {
                "id": "6.3.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.3.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion",
        "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0009396 folic acid-containing compound biosynthetic process",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0G2L1F4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2L1F4",
                "type": "external"
            }
        ],
        "mass": 17861.0,
        "length": 157,
        "protein_name": "Dr1-associated corepressor",
        "gene_name": "LOC100535468",
        "organism": "Zebrafish",
        "refseq_name": "dr1-associated corepressor isoform X1",
        "refseq_ac": [
            {
                "id": "XP_003200419",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200419",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100535468",
        "gene_names_refseq": "LOC100535468",
        "protein_names_uniprotkb": "Dr1-associated corepressor; Dr1-associated protein 1; Negative cofactor 2-alpha",
        "protein_names_refseq": "dr1-associated corepressor isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100535468)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200419.1. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0001046 core promoter sequence-specific DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0017054 negative cofactor 2 complex",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0006351 DNA-templated transcription",
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        "kg_view_protein": true
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            {
                "id": "A0A0G2L2I4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2L2I4",
                "type": "external"
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        ],
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        "length": 93,
        "protein_name": "C-C motif chemokine",
        "gene_name": "ccl36.1",
        "organism": "Zebrafish",
        "refseq_name": "C-C motif chemokine 36.1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001373675",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373675",
                "type": "external"
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        "gene_names_uniprotkb": "ccl36.1; CCL-CUi; CCL-chr7a; CCL36ab",
        "gene_names_refseq": "CCL-CUi; CCL-chr7a; CCL36ab; ccl36.1",
        "protein_names_uniprotkb": "C-C motif chemokine",
        "protein_names_refseq": "C-C motif chemokine 36.1 precursor; chemokine CCL-CUi",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100537088);  (R-DRE-380108);  (R-DRE-416476);  (R-DRE-418594);  (R-DRE-444473)",
        "pathway_count": 5,
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        "publication_id_list": "16365434;18482437;23145839;29760055;32605167;34523214",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01016940.1, EH487952.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Aug 8, 2023 this sequence version replaced NP_001108569.1, XP_003199028.1., [RefSeq]; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV)., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005615 extracellular space",
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        "kg_view_protein": true
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2L2Q2",
                "type": "external"
            }
        ],
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        "protein_name": "Complex III subunit 9",
        "gene_name": "uqcr10",
        "organism": "Zebrafish",
        "refseq_name": "cytochrome b-c1 complex subunit 9",
        "refseq_ac": [
            {
                "id": "NP_001289407",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289407",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "uqcr10",
        "gene_names_refseq": "uqcr10",
        "protein_names_uniprotkb": "Complex III subunit 9",
        "protein_names_refseq": "TCONS_00052125; cytochrome b-c1 complex subunit 9",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100333064);  (R-DRE-611105);  (R-DRE-9865881)",
        "pathway_count": 3,
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        "publication_id_list": "28252024;28455512;33548715;34141984;36317480;38003559;38508476;38788853",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH435283.1, EH503399.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH435283.1 and EH490607.1. On Oct 22, 2014 this sequence version replaced XP_003200865.1., [RefSeq]; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III",
        "go_biological_process": "GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c",
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        "kg_view_protein": true
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    {
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            {
                "id": "A0A0G2L2X8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2L2X8",
                "type": "external"
            }
        ],
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        "length": 167,
        "protein_name": "Cilia- and flagella-associated protein 68",
        "gene_name": "cfap68",
        "organism": "Zebrafish",
        "refseq_name": "cilia- and flagella-associated protein 68",
        "refseq_ac": [
            {
                "id": "NP_001313533",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313533",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cfap68; c5h11orf1; gb:eh456644",
        "gene_names_refseq": "c5h11orf1; cfap68; gb:eh456644",
        "protein_names_uniprotkb": "Cilia- and flagella-associated protein 68",
        "protein_names_refseq": "UPF0686 protein C11orf1 homolog; cilia- and flagella-associated protein 68",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:797203)",
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        "publication_id_list": "27189481",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025100.1, EB836158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1, EH455520.1 and EH482375.1. On May 21, 2016 this sequence version replaced XP_001334782.3., [RefSeq]; Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8M1P2V3",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005930 axoneme",
        "go_biological_process": "GO:0030317 flagellated sperm motility",
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        "hit_score": 0.2,
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        "kg_view_protein": true
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    {
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            {
                "id": "A0A0G2L3K9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2L3K9",
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            }
        ],
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        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC101886047",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_005171139",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171139",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101886047",
        "gene_names_refseq": "LOC101886047",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "predicted_n_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0G2L4V3_DANRE",
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                "type": "external"
            }
        ],
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        "length": 444,
        "protein_name": "SH3 domain-binding protein 5",
        "gene_name": "sh3bp5a",
        "organism": "Zebrafish",
        "refseq_name": "SH3 domain-binding protein 5",
        "refseq_ac": [
            {
                "id": "XP_682769",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_682769",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sh3bp5a",
        "gene_names_refseq": "sh3bp5a",
        "protein_names_uniprotkb": "SH3 domain-binding protein 5; SH3BP-5",
        "protein_names_refseq": "SH3 domain-binding protein 5",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_682769.4. COMPLETENESS: full length., [RefSeq]; Functions as guanine nucleotide exchange factor (GEF) for RAB11A., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005737 cytoplasm",
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0G2L677",
                "type": "external"
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        ],
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        "protein_name": "Large ribosomal subunit protein bL33m",
        "gene_name": "mrpl33",
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        "refseq_name": "large ribosomal subunit protein bL33m",
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            {
                "id": "NP_001290051",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290051",
                "type": "external"
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        "gene_names_refseq": "im:6911600; mrpl33",
        "protein_names_uniprotkb": "Large ribosomal subunit protein bL33m; 39S ribosomal protein L33, mitochondrial",
        "protein_names_refseq": "large ribosomal subunit protein bL33m",
        "tax_id": 7955,
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        "pathway": " (dre:100536515);  (R-DRE-5389840);  (R-DRE-5419276);  (R-DRE-9937383)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH557056.1, EH490154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH557056.1 and EH465531.1. On Dec 17, 2014 this sequence version replaced XP_003200410.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the protein., [RefSeq]",
        "predicted_glycosites": 0,
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        "kg_view_protein": true
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        ],
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        "protein_name": "Guanine nucleotide-binding protein subunit gamma",
        "gene_name": "gng10",
        "organism": "Zebrafish",
        "refseq_name": "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10",
        "refseq_ac": [
            {
                "id": "NP_001191955",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191955",
                "type": "external"
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        "gene_names_uniprotkb": "gng10",
        "gene_names_refseq": "gng10",
        "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma",
        "protein_names_refseq": "G protein subunit gamma 10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:796780);  (R-DRE-202040);  (R-DRE-381676);  (R-DRE-392170);  (R-DRE-400042);  (R-DRE-416476);  (R-DRE-418594);  (R-DRE-418597);  (R-DRE-420092);  (R-DRE-428930);  (R-DRE-432040);  (R-DRE-456926);  (R-DRE-9856530)",
        "pathway_count": 13,
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011697.1, EH571040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Apr 16, 2011 this sequence version replaced XP_001923216.1., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0031681 G-protein beta-subunit binding",
        "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
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        "kg_view_protein": true
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        ],
        "mass": 89418.0,
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        "protein_name": "Inactive dipeptidyl peptidase 10 isoform X1",
        "gene_name": "LOC101886435",
        "organism": "Zebrafish",
        "refseq_name": "inactive dipeptidyl peptidase 10 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009295302",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295302",
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        ],
        "gene_names_uniprotkb": "LOC101886435",
        "gene_names_refseq": "LOC101886435",
        "protein_names_uniprotkb": "Inactive dipeptidyl peptidase 10 isoform X1",
        "protein_names_refseq": "inactive dipeptidyl peptidase 10 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008236 serine-type peptidase activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0008076 voltage-gated potassium channel complex",
        "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport;GO:0006508 proteolysis",
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    {
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        ],
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        "protein_name": "Zinc finger protein 239-like isoform 1",
        "gene_name": "LOC100148620",
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        "refseq_name": "zinc finger protein 239-like isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001373196",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373196",
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        ],
        "gene_names_uniprotkb": "LOC100148620",
        "gene_names_refseq": "LOC100148620",
        "protein_names_uniprotkb": "Zinc finger protein 239-like isoform 1",
        "protein_names_refseq": "zinc finger protein 239-like isoform 1",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01015828.1, CK698711.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001373196.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome",
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    {
        "uniprot_canonical_ac": "A0A0G2LAJ5-1",
        "uniprot_id": [
            {
                "id": "A0A0G2LAJ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0G2LAJ5",
                "type": "external"
            }
        ],
        "mass": 135527.0,
        "length": 1189,
        "protein_name": "Phospholipid-transporting ATPase",
        "gene_name": "atp8b5b",
        "organism": "Zebrafish",
        "refseq_name": "phospholipid-transporting ATPase ID",
        "refseq_ac": [
            {
                "id": "XP_691903",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691903",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "atp8b5b",
        "gene_names_refseq": "atp8b5b",
        "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1",
        "protein_names_refseq": "phospholipid-transporting ATPase ID",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563450)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_691903.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8N7T7T2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity;GO:0140345 phosphatidylcholine flippase activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005802 trans-Golgi network",
        "go_biological_process": "GO:0045332 phospholipid translocation;GO:0007030 Golgi organization",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0G2LAJ5-1",
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        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0A0H2UKU4-1",
        "uniprot_id": [
            {
                "id": "A0A0H2UKU4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0H2UKU4",
                "type": "external"
            }
        ],
        "mass": 135934.0,
        "length": 1242,
        "protein_name": "Protocadherin-7b",
        "gene_name": "pcdh7b",
        "organism": "Zebrafish",
        "refseq_name": "protocadherin-7b",
        "refseq_ac": [
            {
                "id": "NP_001352582",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352582",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pcdh7b; sb:eu592; si:dkey-104n16.1",
        "gene_names_refseq": "pcdh7b; sb:eu592; si:dkey-104n16.1",
        "protein_names_uniprotkb": "Protocadherin-7b",
        "protein_names_refseq": "novel protocadherin protein; protocadherin 7; protocadherin-7b",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:555504);  (R-DRE-114608);  (R-DRE-8980692);  (R-DRE-9013026)",
        "pathway_count": 4,
        "publication_count": 10,
        "publication_id_list": "22001682;23457027;25931248;26469318;27189481;29576475;34650032;35514229;36936789;37272628",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01029662.1, SRR32588727.2566978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Sep 12, 2018 this sequence version replaced XP_683121.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8N7TCQ2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding",
        "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
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        "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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            {
                "id": "A0A0H2UKW6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0H2UKW6",
                "type": "external"
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        ],
        "mass": 69465.0,
        "length": 645,
        "protein_name": "A-kinase anchor protein 8-like",
        "gene_name": "akap8l",
        "organism": "Zebrafish",
        "refseq_name": "A-kinase anchor protein 8-like",
        "refseq_ac": [
            {
                "id": "NP_998384",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998384",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "akap8l; wu:fc52f04; wu:fe38d08; wu:fm58f09; zgc:85966",
        "gene_names_refseq": "akap8l; wu:fc52f04; wu:fe38d08; wu:fm58f09; zgc:85966",
        "protein_names_uniprotkb": "A-kinase anchor protein 8-like",
        "protein_names_refseq": "A-kinase anchor protein 8-like",
        "tax_id": 7955,
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        "pathway": " (dre:406500)",
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        "publication_id_list": "16109975;25503746;27189481;40044042",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC068435.1, SRR26395014.1398863.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On May 17, 2016 this sequence version replaced NP_998384.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0007076 mitotic chromosome condensation",
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        "kg_view_protein": true
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    {
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            {
                "id": "A0A0J9YJ57_DANRE",
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                "type": "external"
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        ],
        "mass": 99615.0,
        "length": 880,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "ppfibp1a",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005164718",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164718",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ppfibp1a; si:dkey-207j16.2",
        "gene_names_refseq": "ppfibp1a; si:dkey-207j16.2",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:565020)",
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        "publication_id_list": "25601102;25630924;28252024",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005829 cytosol;GO:0048786 presynaptic active zone",
        "go_biological_process": "GO:0007528 neuromuscular junction development",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0A0J9YJ98_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0J9YJ98",
                "type": "external"
            }
        ],
        "mass": 10810.0,
        "length": 99,
        "protein_name": "Essential MCU regulator, mitochondrial",
        "gene_name": "smdt1b",
        "organism": "Zebrafish",
        "refseq_name": "single-pass membrane protein with aspartate-rich tail 1b",
        "refseq_ac": [
            {
                "id": "NP_001313451",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313451",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "smdt1b; si:ch211-133l11.4",
        "gene_names_refseq": "si:ch211-133l11.4; smdt1b",
        "protein_names_uniprotkb": "Essential MCU regulator, mitochondrial; Single-pass membrane protein with aspartate-rich tail 1, mitochondrial",
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        "tax_id": 7955,
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        "pathway": " (dre:100000862);  (R-DRE-8949215);  (R-DRE-8949664);  (R-DRE-9837999)",
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        "function": "Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M1P2S1",
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        "go_cellular_component": "GO:1990246 uniplex complex",
        "go_biological_process": "GO:0036444 calcium import into the mitochondrion;GO:0051560 mitochondrial calcium ion homeostasis",
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0N4STX9",
                "type": "external"
            }
        ],
        "mass": 57871.0,
        "length": 524,
        "protein_name": "AT-rich interactive domain-containing protein 3",
        "gene_name": "arid3a",
        "organism": "Zebrafish",
        "refseq_name": "AT-rich interactive domain-containing protein 3A",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304080",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "arid3a",
        "gene_names_refseq": "arid3a",
        "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 3; ARID domain-containing protein",
        "protein_names_refseq": "AT-rich interactive domain-containing protein 3A",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3B3V9;A0AC58GRM4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0N4STX9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0N4SU47-1",
        "uniprot_id": [
            {
                "id": "A0A0N4SU47_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0N4SU47",
                "type": "external"
            }
        ],
        "mass": 57952.0,
        "length": 501,
        "protein_name": "Cholesterol 24-hydroxylase",
        "gene_name": "cyp46a1.5",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC641477 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001417768",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417768",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cyp46a1.5; zgc:123299",
        "gene_names_refseq": "cyp46a1.5; zgc:123299",
        "protein_names_uniprotkb": "Cholesterol 24-hydroxylase; 1.14.14.25; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; Cytochrome P450 46A1",
        "protein_names_refseq": "uncharacterized protein LOC641477 isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:641477)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.28860724.1, SRR32588729.29345535.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jun 25, 2025 this sequence version replaced NP_001417768.1., [RefSeq]; P450 monooxygenase that plays a major role in cholesterol homeostasis in the brain. Primarily catalyzes the hydroxylation (with S stereochemistry) at C-24 of cholesterol side chain, triggering cholesterol diffusion out of neurons and its further degradation. By promoting constant cholesterol elimination in neurons, may activate the mevalonate pathway and coordinate the synthesis of new cholesterol and nonsterol isoprenoids involved in synaptic activity and learning. Further hydroxylates cholesterol derivatives and hormone steroids on both the ring and side chain of these molecules, converting them into active oxysterols involved in lipid signaling and biosynthesis. Acts as an epoxidase converting cholesta-5,24-dien-3beta-ol/desmosterol into (24S),25-epoxycholesterol, an abundant lipid ligand of nuclear NR1H2 and NR1H3 receptors shown to promote neurogenesis in developing brain. May also catalyze the oxidative metabolism of xenobiotics, such as clotrimazole., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M9PSY7",
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            {
                "id": "1.14.14.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.25",
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            }
        ],
        "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0033781 cholesterol 24-hydroxylase activity",
        "go_cellular_component": "GO:0030425 dendrite;GO:0005789 endoplasmic reticulum membrane;GO:0098794 postsynapse;GO:0098793 presynapse",
        "go_biological_process": "GO:0006707 cholesterol catabolic process",
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    },
    {
        "uniprot_canonical_ac": "A0A0N4SUA6-1",
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0N4SUA6",
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        ],
        "mass": 169182.0,
        "length": 1530,
        "protein_name": "Protein TOPAZ1",
        "gene_name": "topaz1",
        "organism": "Zebrafish",
        "refseq_name": "protein TOPAZ1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009292759",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292759",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "topaz1",
        "gene_names_refseq": "topaz1",
        "protein_names_uniprotkb": "Protein TOPAZ1; Testis- and ovary-specific PAZ domain-containing protein 1",
        "protein_names_refseq": "protein TOPAZ1 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:101883830)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0A8M3AVW5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0030154 cell differentiation;GO:0048137 spermatocyte division",
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                "url": "https://www.uniprot.org/uniprot/A0A0N5E8A0",
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        ],
        "mass": 103999.0,
        "length": 930,
        "protein_name": "Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1",
        "gene_name": "rubcn",
        "organism": "Zebrafish",
        "refseq_name": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005174116",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174116",
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        ],
        "gene_names_uniprotkb": "rubcn",
        "gene_names_refseq": "rubcn",
        "protein_names_uniprotkb": "Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1",
        "protein_names_refseq": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive spinocerebellar ataxia 15 (Disease Ontology:DOID:0080057)",
        "pathway": " (dre:100000896)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0A8M2BLQ4",
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        "go_molecular_function": "GO:1901981 phosphatidylinositol phosphate binding",
        "go_cellular_component": "GO:0005769 early endosome;GO:0005770 late endosome",
        "go_biological_process": "GO:1901097 negative regulation of autophagosome maturation;GO:0045806 negative regulation of endocytosis;GO:0006914 autophagy",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4I9C9",
                "type": "external"
            }
        ],
        "mass": 50528.0,
        "length": 459,
        "protein_name": "Dual specificity protein phosphatase 10",
        "gene_name": "dusp10",
        "organism": "Zebrafish",
        "refseq_name": "dual specificity protein phosphatase 10",
        "refseq_ac": [
            {
                "id": "XP_003200822",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200822",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "dusp10",
        "gene_names_refseq": "dusp10",
        "protein_names_uniprotkb": "Dual specificity protein phosphatase 10; 3.1.3.16; 3.1.3.48",
        "protein_names_refseq": "dual specificity protein phosphatase 10",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100034609);  (R-DRE-112409);  (R-DRE-5675221)",
        "pathway_count": 3,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "secondary_ac_list": "A0A8M1RTC2",
        "ec_number_list": [
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
                "type": "external"
            },
            {
                "id": "3.1.3.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol",
        "go_biological_process": "GO:0002682 regulation of immune system process;GO:0046329 negative regulation of JNK cascade;GO:0060284 regulation of cell development;GO:0051239 regulation of multicellular organismal process",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4I9C9-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4I9E8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4I9E8",
                "type": "external"
            }
        ],
        "mass": 92780.0,
        "length": 829,
        "protein_name": "procollagen-proline 3-dioxygenase",
        "gene_name": "p3h1",
        "organism": "Zebrafish",
        "refseq_name": "prolyl 3-hydroxylase 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002663865",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663865",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "p3h1",
        "gene_names_refseq": "p3h1",
        "protein_names_uniprotkb": "procollagen-proline 3-dioxygenase; 1.14.11.7",
        "protein_names_refseq": "prolyl 3-hydroxylase 1 isoform X1",
        "tax_id": 7955,
        "disease": "osteogenesis imperfecta type 8 (Disease Ontology:DOID:0110336)",
        "pathway": " (dre:553321);  (R-DRE-1650814)",
        "pathway_count": 2,
        "publication_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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            }
        ],
        "go_molecular_function": "GO:0005506 iron ion binding;GO:0031418 L-ascorbic acid binding;GO:0019797 procollagen-proline 3-dioxygenase activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum",
        "go_biological_process": "GO:0032963 collagen metabolic process",
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        "protein_name": "rRNA-processing protein UTP23 homolog",
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        "protein_names_uniprotkb": "rRNA-processing protein UTP23 homolog",
        "protein_names_refseq": "rRNA-processing protein UTP23 homolog isoform X1",
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                "id": "A0A0R4IAD0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IAD0",
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            }
        ],
        "mass": 48785.0,
        "length": 425,
        "protein_name": "G protein-activated inward rectifier potassium channel 4",
        "gene_name": "kcnj5",
        "organism": "Zebrafish",
        "refseq_name": "G protein-activated inward rectifier potassium channel 4",
        "refseq_ac": [
            {
                "id": "XP_700619",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700619",
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            }
        ],
        "gene_names_uniprotkb": "kcnj5",
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        "tax_id": 7955,
        "disease": "atrial fibrillation (Disease Ontology:DOID:0060224); long QT syndrome 13 (Disease Ontology:DOID:0110654); primary hyperaldosteronism (Disease Ontology:DOID:446)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_700619.3. COMPLETENESS: full length., [RefSeq]",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "1.5.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2",
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            }
        ],
        "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex",
        "go_biological_process": "GO:0007399 nervous system development;GO:0034220 monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane",
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    {
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        ],
        "mass": 216009.0,
        "length": 1876,
        "protein_name": "Proteasome activator complex subunit 4A",
        "gene_name": "psme4a",
        "organism": "Zebrafish",
        "refseq_name": "proteasome activator complex subunit 4A",
        "refseq_ac": [
            {
                "id": "NP_001410925",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410925",
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        "gene_names_uniprotkb": "psme4a; si:ch73-101f17.1",
        "gene_names_refseq": "psme4a; si:ch73-101f17.1",
        "protein_names_uniprotkb": "Proteasome activator complex subunit 4A",
        "protein_names_refseq": "proteasome (prosome, macropain) activator subunit 4a; proteasome activator PA200-A; proteasome activator complex subunit 4A",
        "tax_id": 7955,
        "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545)",
        "pathway": " (dre:793897)",
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        "publication_id_list": "26271038;32651405;36768797",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01018484.1, SRR32588733.1803133.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476757 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Aug 28, 2023 this sequence version replaced XP_009305766.1., [RefSeq]; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "zgc:174863",
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            {
                "id": "XP_005166230",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166230",
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        "gene_names_uniprotkb": "zgc:174863; zgc:174863",
        "gene_names_refseq": "zgc:174863",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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                "type": "external"
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        ],
        "mass": 50520.0,
        "length": 459,
        "protein_name": "tRNA (Cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1",
        "gene_name": "nsun6",
        "organism": "Zebrafish",
        "refseq_name": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005169112",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169112",
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        "gene_names_uniprotkb": "nsun6",
        "gene_names_refseq": "nsun6",
        "protein_names_uniprotkb": "tRNA (Cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1",
        "protein_names_refseq": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1",
        "tax_id": 7955,
        "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); autosomal recessive intellectual developmental disorder 82 (Disease Ontology:DOID:0060947)",
        "pathway": " (dre:100149557)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003723 RNA binding;GO:0008173 RNA methyltransferase activity",
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        ],
        "mass": 148833.0,
        "length": 1351,
        "protein_name": "SUN domain-containing ossification factor",
        "gene_name": "suco",
        "organism": "Zebrafish",
        "refseq_name": "SUN domain-containing ossification factor isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005160501",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160501",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "suco",
        "gene_names_refseq": "suco",
        "protein_names_uniprotkb": "SUN domain-containing ossification factor; Membrane protein CH1; SUN-like protein 1",
        "protein_names_refseq": "SUN domain-containing ossification factor isoform X1",
        "tax_id": 7955,
        "disease": "osteogenesis imperfecta type 5 (Disease Ontology:DOID:0110344)",
        "pathway": " (dre:558218)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8M2B794",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030867 rough endoplasmic reticulum membrane;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0001503 ossification;GO:0046850 regulation of bone remodeling",
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                "id": "URGL_DANRE",
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        "mass": 62486.0,
        "length": 549,
        "protein_name": "Ureidoglycolate lyase",
        "gene_name": "ugl",
        "organism": "Zebrafish",
        "refseq_name": "malate synthase-like",
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            }
        ],
        "gene_names_uniprotkb": "ugl",
        "gene_names_refseq": "mlsl; ugl; zmp:0000000758",
        "protein_names_uniprotkb": "Ureidoglycolate lyase; 4.3.2.3; MLSL; MSL; Malate synthase-like",
        "protein_names_refseq": "malate synthase-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564844)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23594743;37043529",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC122227.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH433561.1, EH488762.1, EH537783.1 and EH515288.1., [RefSeq]; Catalyzes the last step of purine degradation by converting ureidoglycolate into glyoxylate and urea (PubMed:37043529). The enzyme is not dependent on a metal cofactor (PubMed:37043529)., [UniProtKB, PubMed]; Ureidoglycolate lyase gene is involved in the conversion of (S)-ureidoglycolate into glyoxylate and urea, the last step of purine catabolism in animals. The protein originated by gene duplication from malate synthase (MS), but it does not have malate synthase activity. It is present in some animals such as fishes, but has been lost in reptiles, birds, and placental mammals., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P3F0",
        "ec_number_list": [
            {
                "id": "4.3.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.2.3",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004474 malate synthase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006097 glyoxylate cycle",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IAX5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IAZ1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IAZ1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IAZ1",
                "type": "external"
            }
        ],
        "mass": 30225.0,
        "length": 260,
        "protein_name": "Structure-specific endonuclease subunit SLX1",
        "gene_name": "slx1b",
        "organism": "Zebrafish",
        "refseq_name": "structure-specific endonuclease subunit SLX1",
        "refseq_ac": [
            {
                "id": "NP_001314786",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314786",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slx1b",
        "gene_names_refseq": "slx1b",
        "protein_names_uniprotkb": "Structure-specific endonuclease subunit SLX1",
        "protein_names_refseq": "SLX1 structure-specific endonuclease subunit homolog B; structure-specific endonuclease subunit SLX1; zmp:0000000823",
        "tax_id": 7955,
        "disease": "Fanconi-like syndrome (Disease Ontology:DOID:0090066)",
        "pathway": " (dre:100001845);  (R-DRE-5693568);  (R-DRE-6783310)",
        "pathway_count": 3,
        "publication_count": 3,
        "publication_id_list": "26469318;27189481;34390914",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019200.1, GFIL01014801.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 27, 2016 this sequence version replaced XP_001337124.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA., [UniProtKB, HAMAP]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P343",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008821 crossover junction DNA endonuclease activity;GO:0017108 5'-flap endonuclease activity;GO:0004519 endonuclease activity",
        "go_cellular_component": "GO:0033557 Slx1-Slx4 complex",
        "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IAZ1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IB08-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IB08_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IB08",
                "type": "external"
            }
        ],
        "mass": 85814.0,
        "length": 759,
        "protein_name": "C-Jun-amino-terminal kinase-interacting protein 1a",
        "gene_name": "mapk8ip1a",
        "organism": "Zebrafish",
        "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 1a",
        "refseq_ac": [
            {
                "id": "NP_001338595",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338595",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mapk8ip1a; mapk8ip1",
        "gene_names_refseq": "mapk8ip1a; mapk8ip1",
        "protein_names_uniprotkb": "C-Jun-amino-terminal kinase-interacting protein 1a",
        "protein_names_refseq": "C-Jun-amino-terminal kinase-interacting protein 1a; mitogen-activated protein kinase 8 interacting protein 1",
        "tax_id": 7955,
        "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dre:100537717)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "27189481;27614751",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.861492.1, SRR32588717.20249067.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 25, 2025 this sequence version replaced NP_001338595.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PAR0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005078 MAP-kinase scaffold activity;GO:0016301 kinase activity;GO:0008432 JUN kinase binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0007254 JNK cascade;GO:0046328 regulation of JNK cascade",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IB08-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IBA6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IBA6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IBA6",
                "type": "external"
            }
        ],
        "mass": 25495.0,
        "length": 227,
        "protein_name": "Uncharacterized protein LOC796591 precursor; Uncharacterized protein isoform X1",
        "gene_name": "si:zfos-741a10.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC796591 precursor",
        "refseq_ac": [
            {
                "id": "NP_001373246",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373246",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:zfos-741a10.3",
        "gene_names_refseq": "si:zfos-741a10.3",
        "protein_names_uniprotkb": "Uncharacterized protein LOC796591 precursor; Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein LOC796591 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:796591)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01024065.1, GFIL01025061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 19, 2020 this sequence version replaced XP_001334154.3., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PUA2",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite",
        "go_biological_process": "GO:0006955 immune response;GO:0046847 filopodium assembly;GO:1904891 positive regulation of excitatory synapse assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A0R4IBA6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IBE2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IBE2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IBE2",
                "type": "external"
            }
        ],
        "mass": 111513.0,
        "length": 1024,
        "protein_name": "Proline-rich transmembrane protein 4",
        "gene_name": "prrt4b",
        "organism": "Zebrafish",
        "refseq_name": "proline-rich transmembrane protein 4",
        "refseq_ac": [
            {
                "id": "XP_005164842",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164842",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "prrt4b",
        "gene_names_refseq": "prrt4b",
        "protein_names_uniprotkb": "Proline-rich transmembrane protein 4",
        "protein_names_refseq": "proline-rich transmembrane protein 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:335883)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2BBY6",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IBE2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IBJ2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IBJ2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IBJ2",
                "type": "external"
            }
        ],
        "mass": 44014.0,
        "length": 383,
        "protein_name": "Ribosome biogenesis protein BRX1 homolog",
        "gene_name": "bxdc2",
        "organism": "Zebrafish",
        "refseq_name": "ribosome biogenesis protein BRX1 homolog",
        "refseq_ac": [
            {
                "id": "NP_001166027",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166027",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bxdc2",
        "gene_names_refseq": "bxdc2",
        "protein_names_uniprotkb": "Ribosome biogenesis protein BRX1 homolog; Brix domain-containing protein 2",
        "protein_names_refseq": "ribosome biogenesis protein BRX1 homolog",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:402823)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "24198278;26566657;27189481",
        "class_list": "",
        "function": "Required for biogenesis of the 60S ribosomal subunit., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NVZ7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding",
        "go_cellular_component": "GO:0005730 nucleolus",
        "go_biological_process": "GO:0006364 rRNA processing;GO:0000027 ribosomal large subunit assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IBJ2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IBQ5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IBQ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IBQ5",
                "type": "external"
            }
        ],
        "mass": 92647.0,
        "length": 833,
        "protein_name": "Protocadherin-20",
        "gene_name": "pcdh20l",
        "organism": "Zebrafish",
        "refseq_name": "protocadherin-20 precursor",
        "refseq_ac": [
            {
                "id": "NP_001338645",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338645",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pcdh20l; si:dkey-27i16.3",
        "gene_names_refseq": "pcdh20l; si:dkey-27i16.3",
        "protein_names_uniprotkb": "Protocadherin-20",
        "protein_names_refseq": "protocadherin-20 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:568796)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23559552;32173538",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01013787.1, GFIL01037406.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On May 23, 2017 this sequence version replaced XP_697243.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PAJ2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IBQ5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IBX9-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IBX9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IBX9",
                "type": "external"
            }
        ],
        "mass": 9647.0,
        "length": 87,
        "protein_name": "Non-histone chromosomal protein HMG-like",
        "gene_name": "hmgn1b",
        "organism": "Zebrafish",
        "refseq_name": "non-histone chromosomal protein HMG-like",
        "refseq_ac": [
            {
                "id": "NP_001373649",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373649",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hmgn1b; im:7159173; linc-mipep; lnc_rps25; lncrps25; si:ch73-1a9.3",
        "gene_names_refseq": "hmgn1b; im:7159173; linc-mipep; lnc_rps25; lncrps25; si:ch73-1a9.3",
        "protein_names_uniprotkb": "Non-histone chromosomal protein HMG-like",
        "protein_names_refseq": "TCONS_00009015; non-histone chromosomal protein HMG-17; non-histone chromosomal protein HMG-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:556254)",
        "pathway_count": 1,
        "publication_count": 6,
        "publication_id_list": "22196729;24705786;27189481;28455512;31549395;37191016",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1227665.1, GFIL01022837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Sep 2, 2020 this sequence version replaced XP_005169261.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2BGK7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003682 chromatin binding;GO:0031492 nucleosomal DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin",
        "go_biological_process": "GO:0007409 axonogenesis;GO:0006325 chromatin organization;GO:0048666 neuron development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A0R4IBX9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ICA2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ICA2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ICA2",
                "type": "external"
            }
        ],
        "mass": 104492.0,
        "length": 939,
        "protein_name": "E3 ubiquitin-protein ligase Topors",
        "gene_name": "toporsb",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein toporsb isoform X1",
        "refseq_ac": [
            {
                "id": "XP_003201680",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201680",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "toporsb",
        "gene_names_refseq": "toporsb",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Topors; 2.3.2.27; RING-type E3 ubiquitin transferase Topors; SUMO1-protein E3 ligase Topors; Topoisomerase I-binding RING finger protein; Topoisomerase I-binding arginine/serine-rich protein; Tumor suppressor p53-binding protein 3",
        "protein_names_refseq": "uncharacterized protein toporsb isoform X1",
        "tax_id": 7955,
        "disease": "retinitis pigmentosa 31 (Disease Ontology:DOID:0110391)",
        "pathway": " (dre:796087)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RPD6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0032391 photoreceptor connecting cilium",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000209 protein polyubiquitination;GO:0006513 protein monoubiquitination",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ICA2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ICA5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ICA5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ICA5",
                "type": "external"
            }
        ],
        "mass": 63338.0,
        "length": 578,
        "protein_name": "Solute carrier family 15 member 4",
        "gene_name": "slc15a4",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 15 member 4",
        "refseq_ac": [
            {
                "id": "NP_001307458",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307458",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc15a4; bZ1L10.1; zgc:56484; zgc:63767",
        "gene_names_refseq": "bZ1L10.1; slc15a4; zgc:56484; zgc:63767",
        "protein_names_uniprotkb": "Solute carrier family 15 member 4",
        "protein_names_refseq": "bZ1L10.1 (novel peptide transporter); solute carrier family 15 (oligopeptide transporter), member 4; solute carrier family 15 member 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:393932);  (R-DRE-427975);  (R-DRE-6798695)",
        "pathway_count": 3,
        "publication_count": 2,
        "publication_id_list": "28694436;37179373",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01038254.1, GDQQ01004094.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Feb 27, 2016 this sequence version replaced XP_005167300.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and orthologous alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P8Q5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0015293 symporter activity;GO:0005290 L-histidine transmembrane transporter activity;GO:0071916 dipeptide transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0005765 lysosomal membrane;GO:0031901 early endosome membrane",
        "go_biological_process": "GO:0015031 protein transport;GO:0045087 innate immune response;GO:0140206 dipeptide import across plasma membrane",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4ICA5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ICC1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ICC1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ICC1",
                "type": "external"
            }
        ],
        "mass": 82033.0,
        "length": 728,
        "protein_name": "Twinkle mtDNA helicase",
        "gene_name": "twnk",
        "organism": "Zebrafish",
        "refseq_name": "twinkle mtDNA helicase",
        "refseq_ac": [
            {
                "id": "NP_001264527",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264527",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "twnk; fi04d09; peo1; wu:fi04d09",
        "gene_names_refseq": "fi04d09; peo1; twnk; wu:fi04d09",
        "protein_names_uniprotkb": "Twinkle mtDNA helicase; 5.6.2.3; Twinkle protein, mitochondrial",
        "protein_names_refseq": "progressive external ophthalmoplegia 1; twinkle mtDNA helicase; twinkle protein, mitochondrial-like",
        "tax_id": 7955,
        "disease": "Perrault syndrome (Disease Ontology:DOID:0050857); mitochondrial DNA depletion syndrome (Disease Ontology:DOID:0070329); mitochondrial DNA depletion syndrome 7 (Disease Ontology:DOID:0080126); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5 (Disease Ontology:DOID:0111518); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3 (Disease Ontology:DOID:0111520); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); Parkinson's disease (Disease Ontology:DOID:14330)",
        "pathway": " (dre:100330448);  (R-DRE-9837999);  (R-DRE-9913635)",
        "pathway_count": 3,
        "publication_count": 8,
        "publication_id_list": "18335061;22465854;23516612;25771346;27189481;27924917;28535465;32806454",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01006689.1, SRR26395014.1082722.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1 and EV561328.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Mitochondrial helicase involved in mtDNA replication and repair. Might have a role in mtDNA repair. Has DNA strand separation activity needed to form a processive replication fork for leading strand synthesis which is catalyzed by the formation of a replisome complex with POLG and mtSDB. Preferentially unwinds DNA substrates with pre-existing 5'-and 3'- single-stranded tails but is also active on a 5'- flap substrate. Can dissociate the invading strand of immobile or mobile D-loop DNA structures irrespective of the single strand polarity of the third strand. In addition to its DNA strand separation activity, also has DNA strand annealing, DNA strand-exchange and DNA branch migration activities., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 7,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P494",
        "ec_number_list": [
            {
                "id": "2.3.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-",
                "type": "external"
            },
            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
                "type": "external"
            },
            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
                "type": "external"
            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "5.6.2.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4",
                "type": "external"
            },
            {
                "id": "5.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3",
                "type": "external"
            },
            {
                "id": "3.6.4.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
                "type": "external"
            },
            {
                "id": "3.4.21.53",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53",
                "type": "external"
            },
            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
            },
            {
                "id": "2.7.4.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3",
                "type": "external"
            },
            {
                "id": "7.6.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
                "type": "external"
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Protein FAM174C precursor",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P7H7",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A0R4ICP9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ICR1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ICR1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ICR1",
                "type": "external"
            }
        ],
        "mass": 62898.0,
        "length": 570,
        "protein_name": "Nectin-4",
        "gene_name": "nectin4b",
        "organism": "Zebrafish",
        "refseq_name": "nectin-4",
        "refseq_ac": [
            {
                "id": "XP_001334985",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334985",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nectin4b",
        "gene_names_refseq": "nectin4b",
        "protein_names_uniprotkb": "Nectin-4",
        "protein_names_refseq": "nectin-4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:794920);  (R-DRE-418990);  (R-DRE-420597)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_001334985.5. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1PUD3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0098631 cell adhesion mediator activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction",
        "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ICR1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ICR8-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ICR8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ICR8",
                "type": "external"
            }
        ],
        "mass": 43957.0,
        "length": 392,
        "protein_name": "Basigin",
        "gene_name": "bsg",
        "organism": "Zebrafish",
        "refseq_name": "basigin isoform 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_937785",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_937785",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bsg; wu:fb26a05; wu:fo98e12",
        "gene_names_refseq": "bsg; wu:fb26a05; wu:fo98e12",
        "protein_names_uniprotkb": "Basigin",
        "protein_names_refseq": "5A11/Basigin-2; basigin isoform 1 precursor; cd147",
        "tax_id": 7955,
        "disease": "transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial carcinoma (Disease Ontology:DOID:2871); breast ductal carcinoma (Disease Ontology:DOID:3007); lung squamous cell carcinoma (Disease Ontology:DOID:3907); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); ovary serous adenocarcinoma (Disease Ontology:DOID:5744)",
        "pathway": " (R-DRE-1474228);  (R-DRE-210991);  (R-DRE-216083);  (R-DRE-433692);  (R-DRE-9749641)",
        "pathway_count": 5,
        "publication_count": 11,
        "publication_id_list": "12939332;15520368;16109975;21729873;25840431;26908177;27294876;28252024;31468037;34046029;40044042",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.407213.1, SRR26395062.363575.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1, DT058336.1, EH536274.1, CK356411.1, EH563077.1 and EH520368.1. On Aug 20, 2015 this sequence version replaced NP_937785.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 1,
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        "predicted_c_glycosites": 0,
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        "secondary_ac_list": "A0A8M1PDN1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0030424 axon;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411 axon guidance;GO:0070593 dendrite self-avoidance",
        "synthesized_glycan_count": 0,
        "hit_score": 1.4,
        "record_id": "A0A0R4ICR8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0100000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IG09_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IG09",
                "type": "external"
            }
        ],
        "mass": 28005.0,
        "length": 262,
        "protein_name": "Eukaryotic translation initiation factor 4H",
        "gene_name": "eif4h",
        "organism": "Zebrafish",
        "refseq_name": "eukaryotic translation initiation factor 4H isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001184257",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184257",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "eif4h; wbscr1; zgc:77282",
        "gene_names_refseq": "eif4h; wbscr1; zgc:77282",
        "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4H",
        "protein_names_refseq": "Williams-Beuren syndrome chromosome region 1; eukaryotic translation initiation factor 4H isoform 1",
        "tax_id": 7955,
        "disease": "Williams-Beuren syndrome (Disease Ontology:DOID:1928)",
        "pathway": " (dre:402996);  (R-DRE-156827);  (R-DRE-72649);  (R-DRE-72662);  (R-DRE-72702)",
        "pathway_count": 5,
        "publication_count": 6,
        "publication_id_list": "11517306;21468032;26469318;28252024;31017557;40044042",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC065640.1, SRR26395062.610911.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, FP141411.1, EH552521.1 and EH515860.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M1NUW6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity",
        "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0005634 nucleus",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
        "record_id": "A0A0R4IG09-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ICZ3-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ICZ3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ICZ3",
                "type": "external"
            }
        ],
        "mass": 88588.0,
        "length": 796,
        "protein_name": "Enhancer of polycomb homolog",
        "gene_name": "epc1a",
        "organism": "Zebrafish",
        "refseq_name": "enhancer of polycomb homolog 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_695062",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695062",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "epc1a",
        "gene_names_refseq": "epc1a",
        "protein_names_uniprotkb": "Enhancer of polycomb homolog",
        "protein_names_refseq": "enhancer of polycomb homolog 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_695062.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7T863",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0032777 piccolo histone acetyltransferase complex",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ICZ3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ID81-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ID81_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ID81",
                "type": "external"
            }
        ],
        "mass": 53796.0,
        "length": 478,
        "protein_name": "Rab11 family-interacting protein 2",
        "gene_name": "rab11fip2",
        "organism": "Zebrafish",
        "refseq_name": "rab11 family-interacting protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009305544",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305544",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rab11fip2",
        "gene_names_refseq": "rab11fip2",
        "protein_names_uniprotkb": "Rab11 family-interacting protein 2",
        "protein_names_refseq": "rab11 family-interacting protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100334729)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_phosphosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3B7Z5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0031267 small GTPase binding",
        "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005768 endosome;GO:0055038 recycling endosome membrane;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0015031 protein transport;GO:0045055 regulated exocytosis;GO:0001755 neural crest cell migration;GO:0007154 cell communication;GO:0023052 signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ID81-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ID82-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ID82_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ID82",
                "type": "external"
            }
        ],
        "mass": 68103.0,
        "length": 599,
        "protein_name": "Vacuolar protein sorting-associated protein 33A",
        "gene_name": "vps33a",
        "organism": "Zebrafish",
        "refseq_name": "vacuolar protein sorting-associated protein 33A",
        "refseq_ac": [
            {
                "id": "NP_001093443",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093443",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "vps33a; im:7136893; wu:fc08g01; wu:fc26c10",
        "gene_names_refseq": "im:7136893; vps33a; wu:fc08g01; wu:fc26c10",
        "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 33A",
        "protein_names_refseq": "vacuolar protein sorting 33 homolog A; vacuolar protein sorting 33A; vacuolar protein sorting-associated protein 33A",
        "tax_id": 7955,
        "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)",
        "pathway": " (dre:448942)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "16284120;23639161;28252024;31495570",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC095344.1, GDQH01008230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jul 26, 2007 this sequence version replaced XP_683201.2., [RefSeq]; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS16 but not VIPAS39. The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NDX2",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005769 early endosome;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030136 clathrin-coated vesicle",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A0R4ID82-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IDC9-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IDC9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IDC9",
                "type": "external"
            }
        ],
        "mass": 31324.0,
        "length": 289,
        "protein_name": "CXXC-type zinc finger protein 4",
        "gene_name": "cxxc4",
        "organism": "Zebrafish",
        "refseq_name": "CXXC-type zinc finger protein 4",
        "refseq_ac": [
            {
                "id": "XP_001345418",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345418",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cxxc4",
        "gene_names_refseq": "cxxc4",
        "protein_names_uniprotkb": "CXXC-type zinc finger protein 4",
        "protein_names_refseq": "CXXC-type zinc finger protein 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100006754)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001345418.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1Q7Z2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008327 methyl-CpG binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0016055 Wnt signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IDC9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IDK5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IDK5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IDK5",
                "type": "external"
            }
        ],
        "mass": 49391.0,
        "length": 436,
        "protein_name": "Serine/threonine-protein kinase 40",
        "gene_name": "stk40",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase 40 isoform X2",
        "refseq_ac": [
            {
                "id": "XP_068070273",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070273",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "stk40",
        "gene_names_refseq": "stk40",
        "protein_names_uniprotkb": "Serine/threonine-protein kinase 40; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase 40 isoform X2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564859)",
        "pathway_count": 1,
        "publication_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be a negative regulator of NF-kappa-B and p53-mediated gene transcription., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8N7UV17",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
                "type": "external"
            },
            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            },
            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0043408 regulation of MAPK cascade",
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        "hit_score": 0.1,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4IDN5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IDN5",
                "type": "external"
            }
        ],
        "mass": 47215.0,
        "length": 418,
        "protein_name": "Sorting nexin-8 isoform X1",
        "gene_name": "snx8b",
        "organism": "Zebrafish",
        "refseq_name": "sorting nexin-8 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009304805",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304805",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "snx8b",
        "gene_names_refseq": "snx8b",
        "protein_names_uniprotkb": "Sorting nexin-8 isoform X1",
        "protein_names_refseq": "sorting nexin-8 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:799225)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3AY83",
        "ec_number_list": [],
        "go_molecular_function": "GO:0035091 phosphatidylinositol binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0031901 early endosome membrane;GO:0016020 membrane",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034498 early endosome to Golgi transport;GO:0042147 retrograde transport, endosome to Golgi",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IDN5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IDV7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IDV7",
                "type": "external"
            }
        ],
        "mass": 29717.0,
        "length": 265,
        "protein_name": "Neurexophilin",
        "gene_name": "nxph2b",
        "organism": "Zebrafish",
        "refseq_name": "neurexophilin-2b precursor",
        "refseq_ac": [
            {
                "id": "NP_001313335",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313335",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nxph2b",
        "gene_names_refseq": "nxph2b",
        "protein_names_uniprotkb": "Neurexophilin",
        "protein_names_refseq": "neurexophilin-2b precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:797297)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH591562.1, EH589911.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476755, SAMEA4476758 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 17, 2016 this sequence version replaced XP_001337769.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May be signaling molecules that resemble neuropeptides., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P7X2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005102 signaling receptor binding",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A0R4IDV7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IE17_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IE17",
                "type": "external"
            }
        ],
        "mass": 102590.0,
        "length": 930,
        "protein_name": "LIF receptor subunit alpha a precursor",
        "gene_name": "lifra",
        "organism": "Zebrafish",
        "refseq_name": "LIF receptor subunit alpha a precursor",
        "refseq_ac": [
            {
                "id": "NP_001014328",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014328",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lifra; lifr.a; zgc:112989",
        "gene_names_refseq": "lifr.a; lifra; zgc:112989",
        "protein_names_uniprotkb": "LIF receptor subunit alpha a precursor",
        "protein_names_refseq": "LIF receptor subunit alpha a precursor; leukemia inhibitory factor receptor alpha a; leukemia inhibitory factor receptor.a",
        "tax_id": 7955,
        "disease": "congenital anomalies of the kidney and urinary tract (Disease Ontology:DOID:0080205); primary localized cutaneous amyloidosis 1 (Disease Ontology:DOID:0080930); osteochondrodysplasia (Disease Ontology:DOID:2256)",
        "pathway": " (dre:541493);  (R-DRE-6788467)",
        "pathway_count": 2,
        "publication_count": 9,
        "publication_id_list": "17640376;23901114;25162623;25263554;27189481;30267687;33527896;35134499;36846595",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC091862.1, GDQH01000961.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Nov 25, 2025 this sequence version replaced NP_001014328.2. Sequence Note:., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A0R4IC29;A0A8M1N4U6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity",
        "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane",
        "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019221 cytokine-mediated signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "A0A0R4IE17-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IE38-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IE38_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IE38",
                "type": "external"
            }
        ],
        "mass": 10685.0,
        "length": 94,
        "protein_name": "Small ubiquitin-related modifier",
        "gene_name": "sumo2a",
        "organism": "Zebrafish",
        "refseq_name": "small ubiquitin like modifier 2a",
        "refseq_ac": [
            {
                "id": "NP_001373345",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373345",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sumo2a; si:ch211-108p22.3",
        "gene_names_refseq": "si:ch211-108p22.3; sumo2a",
        "protein_names_uniprotkb": "Small ubiquitin-related modifier; SUMO",
        "protein_names_refseq": "SMT3 suppressor of mif two 3 homolog 2a; small ubiquitin like modifier 2a",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100334083)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395017.944115.1, SRR26395039.401284.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Aug 22, 2020 this sequence version replaced XP_002662402.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RH96",
        "ec_number_list": [],
        "go_molecular_function": "GO:0044389 ubiquitin-like protein ligase binding;GO:0031386 protein tag activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0016925 protein sumoylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A0R4IE38-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IE87-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IE87_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IE87",
                "type": "external"
            }
        ],
        "mass": 6674.0,
        "length": 63,
        "protein_name": "Metallothionein",
        "gene_name": "mtbl",
        "organism": "Zebrafish",
        "refseq_name": "metallothionein-B-like",
        "refseq_ac": [
            {
                "id": "NP_001188398",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188398",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mtbl; mt-b",
        "gene_names_refseq": "mt-b; mtbl",
        "protein_names_uniprotkb": "Metallothionein",
        "protein_names_refseq": "metallothionein-B-like; smtB",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569445)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "18579444;21147257;22387671;26025641;26198291;27329524;28315003;28617195;31839624;33407100",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH488466.1, EH503413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH488466.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Metallothioneins have a high content of cysteine residues that bind various heavy metals., [UniProtKB, UniProtKB, UniProtKB]; Report expression of similar to metallothionein-B(smt-B) upon cadmium exposure and cold shock in zebrafish (Danio rerio)., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NYX3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046872 metal ion binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0001525 angiogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IE87-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IEA6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IEA6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IEA6",
                "type": "external"
            }
        ],
        "mass": 51585.0,
        "length": 443,
        "protein_name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B",
        "gene_name": "ppp2r2bb",
        "organism": "Zebrafish",
        "refseq_name": "protein phosphatase 2, regulatory subunit B, beta b",
        "refseq_ac": [
            {
                "id": "NP_001025293",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025293",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ppp2r2bb; ppp2r2b; zgc:101861",
        "gene_names_refseq": "ppp2r2bb; ppp2r2b; zgc:101861",
        "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B",
        "protein_names_refseq": "protein phosphatase 2, regulatory subunit B, beta b",
        "tax_id": 7955,
        "disease": "spinocerebellar ataxia 12 (Disease Ontology:DOID:0050962); Alzheimer's disease (Disease Ontology:DOID:10652); breast cancer (Disease Ontology:DOID:1612); systemic lupus erythematosus (Disease Ontology:DOID:9074); brain disease (Disease Ontology:DOID:936)",
        "pathway": " (dre:558810)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "27296292;33015043",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031237.1, SRR32588718.25569338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Nov 1, 2008 this sequence version replaced NP_001025293.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1N7E1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0019888 protein phosphatase regulator activity",
        "go_cellular_component": "GO:0000159 protein phosphatase type 2A complex",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IEA6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IED7-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IED7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IED7",
                "type": "external"
            }
        ],
        "mass": 49838.0,
        "length": 441,
        "protein_name": "Rab GDP dissociation inhibitor",
        "gene_name": "zgc:112334",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC619199",
        "refseq_ac": [
            {
                "id": "NP_001307001",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307001",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "zgc:112334",
        "gene_names_refseq": "zgc:112334",
        "protein_names_uniprotkb": "Rab GDP dissociation inhibitor",
        "protein_names_refseq": "uncharacterized protein LOC619199",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:619199)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "12477932;28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.1255960.1, SRR32588729.7368899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476739 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments, RNA-seq data and orthologous data., [RefSeq]; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP., [UniProtKB, UniProtKB]; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P8K7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005093 Rab GDP-dissociation inhibitor activity",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol",
        "go_biological_process": "GO:0015031 protein transport;GO:0007264 small GTPase-mediated signal transduction;GO:0016192 vesicle-mediated transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IED7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IEE5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IEE5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IEE5",
                "type": "external"
            }
        ],
        "mass": 167628.0,
        "length": 1481,
        "protein_name": "Uncharacterized protein si:ch211-261d7.6",
        "gene_name": "si:ch211-261d7.6",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-261d7.6",
        "refseq_ac": [
            {
                "id": "XP_017206987",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206987",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-261d7.6",
        "gene_names_refseq": "si:ch211-261d7.6",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-261d7.6",
        "protein_names_refseq": "uncharacterized protein si:ch211-261d7.6",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:108179605)",
        "pathway_count": 1,
        "publication_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0005634 nucleus",
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        "gene_name": "unc5da",
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        "refseq_ac": [
            {
                "id": "NP_001315278",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315278",
                "type": "external"
            }
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        "protein_names_refseq": "unc-5 homolog Da; unc-5 homolog D; unc-5 netrin receptor Da precursor",
        "tax_id": 7955,
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        "pathway": " (dre:566274)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01042735.1, SRR32588730.10812539.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_001315278.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and RNA-seq  and orthologous data., [RefSeq]; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding., [UniProtKB, UniProtKB, UniProtKB]",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IEK2",
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        "protein_name": "Probable G-protein coupled receptor 132b",
        "gene_name": "gpr132b",
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            {
                "id": "NP_001020718",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020718",
                "type": "external"
            }
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        "gene_names_refseq": "gpr132b; si:ch211-20b12.2; zgc:136260",
        "protein_names_uniprotkb": "Probable G-protein coupled receptor 132b",
        "protein_names_refseq": "G protein-coupled receptor -like; probable G-protein coupled receptor 132b",
        "tax_id": 7955,
        "disease": "autoimmune disease (Disease Ontology:DOID:417)",
        "pathway": " (dre:566903);  (R-DRE-373076);  (R-DRE-416476)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC116473.1, GDQH01021230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Nov 26, 2014 this sequence version replaced NP_001020718.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; GPR132 responds to a select panel of oxygenated polyunsaturated fatty acids to enhance both embryonic and adult hematopoiesis., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0010447 response to acidic pH;GO:0010972 negative regulation of G2/M transition of mitotic cell cycle",
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IEQ2",
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        ],
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        "length": 385,
        "protein_name": "Calcium/manganese antiporter SLC30A10",
        "gene_name": "slc30a10",
        "organism": "Zebrafish",
        "refseq_name": "calcium/manganese antiporter SLC30A10",
        "refseq_ac": [
            {
                "id": "NP_001121706",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121706",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "slc30a10; ZnT10",
        "gene_names_refseq": "ZnT10; slc30a10",
        "protein_names_uniprotkb": "Calcium/manganese antiporter SLC30A10",
        "protein_names_refseq": "calcium/manganese antiporter SLC30A10; solute carrier family 30 (zinc transporter), member 10",
        "tax_id": 7955,
        "disease": "hypermanganesemia with dystonia 1 (Disease Ontology:DOID:0080536)",
        "pathway": " (dre:555724);  (R-DRE-425410)",
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        "publication_id_list": "11698295;16689696;27411634;28692648;35429189;36044573;36693371",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.54654022.1, SRR32588728.28588260.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Apr 20, 2018 this sequence version replaced XP_009305899.1, NP_001121706.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Xpressing either wild-type or mutant forms of SLC30A10 was sufficient to inhibit the effect of ATP2C1 in response to Mn challenge in both zebrafish embryos and HeLa cells. These findings suggest that either activating ATP2C1 or restoring the Mn-induced trafficking of ATP2C1 can reduce Mn accumulation, providing a possible target for treating HMDPC. Publication Status: Online-Only, [RefSeq, PubMed]",
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        "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0010312 detoxification of zinc ion;GO:0071577 zinc ion transmembrane transport;GO:0006882 intracellular zinc ion homeostasis;GO:0006828 manganese ion transport;GO:0055071 manganese ion homeostasis",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IEU4",
                "type": "external"
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        ],
        "mass": 111375.0,
        "length": 979,
        "protein_name": "ELKS/Rab6-interacting/CAST family member 1a isoform X1",
        "gene_name": "erc1a",
        "organism": "Zebrafish",
        "refseq_name": "ELKS/Rab6-interacting/CAST family member 1a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009296278",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296278",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "erc1a; zgc:198416",
        "gene_names_refseq": "erc1a; zgc:198416",
        "protein_names_uniprotkb": "ELKS/Rab6-interacting/CAST family member 1a isoform X1",
        "protein_names_refseq": "ELKS/Rab6-interacting/CAST family member 1a isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:548606)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0098882 structural constituent of presynaptic active zone",
        "go_cellular_component": "GO:0098831 presynaptic active zone cytoplasmic component;GO:0005856 cytoskeleton;GO:0098793 presynapse",
        "go_biological_process": "GO:0048790 maintenance of presynaptic active zone structure",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IFD5",
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        "protein_name": "Ras-associating and dilute domain-containing protein-like",
        "gene_name": "radil2a",
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        "refseq_name": "Ras-associating and dilute domain-containing protein-like",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272317",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "radil2a; radil-b; si:ch73-281f12.4; zmp:0000000679",
        "gene_names_refseq": "radil-b; radil2a; si:ch73-281f12.4; zmp:0000000679",
        "protein_names_uniprotkb": "Ras-associating and dilute domain-containing protein-like",
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        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: JF519851.1, GDQH01020808.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced NP_001272317.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0051020 GTPase binding",
        "go_cellular_component": "GO:0005911 cell-cell junction",
        "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0035024 negative regulation of Rho protein signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IFD5-1",
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        "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IFG3-1",
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            {
                "id": "A0A0R4IFG3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IFG3",
                "type": "external"
            }
        ],
        "mass": 127151.0,
        "length": 1145,
        "protein_name": "Transcription termination factor 2",
        "gene_name": "ttf2",
        "organism": "Zebrafish",
        "refseq_name": "transcription termination factor 2",
        "refseq_ac": [
            {
                "id": "XP_005168676",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168676",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ttf2",
        "gene_names_refseq": "ttf2",
        "protein_names_uniprotkb": "Transcription termination factor 2; RNA polymerase II termination factor; Transcription release factor 2",
        "protein_names_refseq": "transcription termination factor 2",
        "tax_id": 7955,
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        "pathway": " (dre:555382)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2BFW3",
        "ec_number_list": [
            {
                "id": "2.3.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-",
                "type": "external"
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            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
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            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
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            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "5.6.2.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4",
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            {
                "id": "5.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3",
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            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
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            {
                "id": "2.7.4.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3",
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            },
            {
                "id": "7.6.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2",
                "type": "external"
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            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
                "type": "external"
            },
            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            },
            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
            },
            {
                "id": "3.6.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
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            },
            {
                "id": "3.6.1.15",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15",
                "type": "external"
            },
            {
                "id": "3.6.4.10",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10",
                "type": "external"
            },
            {
                "id": "5.6.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
                "type": "external"
            },
            {
                "id": "5.6.2.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex",
        "go_biological_process": "GO:0006281 DNA repair;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0006353 DNA-templated transcription termination",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IFG3-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4IFI0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IFI0",
                "type": "external"
            }
        ],
        "mass": 152557.0,
        "length": 1363,
        "protein_name": "Regulatory-associated protein of mTOR",
        "gene_name": "rptor",
        "organism": "Zebrafish",
        "refseq_name": "regulatory-associated protein of mTOR isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021327417",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327417",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rptor",
        "gene_names_refseq": "rptor",
        "protein_names_uniprotkb": "Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein",
        "protein_names_refseq": "regulatory-associated protein of mTOR isoform X1",
        "tax_id": 7955,
        "disease": "nicotine dependence (Disease Ontology:DOID:0050742)",
        "pathway": " (dre:560455);  (R-DRE-1632852);  (R-DRE-165159);  (R-DRE-166208);  (R-DRE-3371571);  (R-DRE-380972);  (R-DRE-5628897);  (R-DRE-8943724);  (R-DRE-9639288)",
        "pathway_count": 9,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2B3N3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005764 lysosome;GO:0031931 TORC1 complex",
        "go_biological_process": "GO:0010506 regulation of autophagy;GO:0030307 positive regulation of cell growth;GO:0006914 autophagy;GO:0009267 cellular response to starvation;GO:0038202 TORC1 signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IFI0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IFJ3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IFJ3",
                "type": "external"
            }
        ],
        "mass": 56927.0,
        "length": 523,
        "protein_name": "Large neutral amino acids transporter small subunit 1",
        "gene_name": "slc7a5",
        "organism": "Zebrafish",
        "refseq_name": "large neutral amino acids transporter small subunit 1",
        "refseq_ac": [
            {
                "id": "NP_001121830",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121830",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc7a5; LAT1",
        "gene_names_refseq": "LAT1; slc7a5",
        "protein_names_uniprotkb": "Large neutral amino acids transporter small subunit 1",
        "protein_names_refseq": "large neutral amino acids transporter small subunit 1; solute carrier family 7 (amino acid transporter light chain, L system), member 5",
        "tax_id": 7955,
        "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); large cell neuroendocrine carcinoma (Disease Ontology:DOID:0050872); autism spectrum disorder (Disease Ontology:DOID:0060041); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); stomach cancer (Disease Ontology:DOID:10534); esophageal carcinoma (Disease Ontology:DOID:1107); esophagitis (Disease Ontology:DOID:11963); rectum adenocarcinoma (Disease Ontology:DOID:1996); colon cancer (Disease Ontology:DOID:219); glioblastoma (Disease Ontology:DOID:3068); malignant astrocytoma (Disease Ontology:DOID:3069); extrahepatic bile duct adenocarcinoma (Disease Ontology:DOID:3495); gastric adenocarcinoma (Disease Ontology:DOID:3717); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); bile duct adenocarcinoma (Disease Ontology:DOID:4896); bile duct carcinoma (Disease Ontology:DOID:4897); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); malignant pleural mesothelioma (Disease Ontology:DOID:7474); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:797250);  (R-DRE-210991);  (R-DRE-352230);  (R-DRE-71240)",
        "pathway_count": 4,
        "publication_count": 10,
        "publication_id_list": "25051050;25872869;26469318;27189481;28694436;31513589;32831172;33330465;33745965;37979715",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01032991.1, GFIL01025102.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000025.1. On Jul 31, 2008 this sequence version replaced XP_001919407.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 26,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NHX4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0015175 neutral L-amino acid transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0015804 neutral amino acid transport;GO:0003333 amino acid transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IFJ3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IFJ7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IFJ7",
                "type": "external"
            }
        ],
        "mass": 46804.0,
        "length": 417,
        "protein_name": "Creatine kinase S-type, mitochondrial",
        "gene_name": "ckmt2a",
        "organism": "Zebrafish",
        "refseq_name": "creatine kinase, mitochondrial 2a (sarcomeric) isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001295538",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001295538",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ckmt2a; fi14g08; wu:fi14g08; zgc:56085",
        "gene_names_refseq": "ckmt2a; fi14g08; wu:fi14g08; zgc:56085",
        "protein_names_uniprotkb": "Creatine kinase S-type, mitochondrial; 2.7.3.2; Sarcomeric mitochondrial creatine kinase",
        "protein_names_refseq": "creatine kinase, mitochondrial 2a (sarcomeric) isoform 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:327506);  (R-DRE-71288)",
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        "publication_count": 9,
        "publication_id_list": "19482995;26046835;26469318;27189481;28138518;29762122;31195116;33105605;33857482",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.41835775.1, SRR32588729.29474114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH439325.1, EH115450.1, EH461171.1, JBMGRA010000010.1 and EH612110.1. Transcript Variant: This variant (2) uses an alternate internal exon compared to variant 1. The encoded isoform is the same length but differs in amino acid sequence compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P728",
        "ec_number_list": [
            {
                "id": "2.7.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.3.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "A0A0R4IFJ7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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            {
                "id": "A0A0R4IFY3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IFY3",
                "type": "external"
            }
        ],
        "mass": 39743.0,
        "length": 345,
        "protein_name": "5-hydroxytryptamine (Serotonin) receptor 5A, genome duplicate a",
        "gene_name": "htr5aa",
        "organism": "Zebrafish",
        "refseq_name": "5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a",
        "refseq_ac": [
            {
                "id": "NP_001119882",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119882",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "htr5aa; htr5a; si:dkey-265a7.5",
        "gene_names_refseq": "htr5aa; htr5a; si:dkey-265a7.5",
        "protein_names_uniprotkb": "5-hydroxytryptamine (Serotonin) receptor 5A, genome duplicate a",
        "protein_names_refseq": "5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate a",
        "tax_id": 7955,
        "disease": "intracranial hypertension (Disease Ontology:DOID:9428)",
        "pathway": " (dre:100038775);  (R-DRE-390666);  (R-DRE-418594)",
        "pathway_count": 3,
        "publication_count": 9,
        "publication_id_list": "26565906;26822114;27424782;27703173;28837927;32209227;32892009;33171223;37207274",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.15483633.1, SRR32588729.6873066.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476767, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On or before May 28, 2009 this sequence version replaced NP_001083024.1, NP_001119882.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "secondary_ac_list": "A0A8M1NJ85;A0AC58G9B1;A0AC58G9D3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0004938 alpha2-adrenergic receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse",
        "go_biological_process": "GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "A0A0R4IFY3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IFY9-1",
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            {
                "id": "A0A0R4IFY9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IFY9",
                "type": "external"
            }
        ],
        "mass": 41638.0,
        "length": 377,
        "protein_name": "Sterile alpha motif domain containing 1a",
        "gene_name": "samd1a",
        "organism": "Zebrafish",
        "refseq_name": "sterile alpha motif domain containing 1a",
        "refseq_ac": [
            {
                "id": "NP_001303918",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303918",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "samd1a; zgc:153652",
        "gene_names_refseq": "samd1a; zgc:153652",
        "protein_names_uniprotkb": "Sterile alpha motif domain containing 1a",
        "protein_names_refseq": "sterile alpha motif domain containing 1a",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:768149)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "27189481;34315984",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01034409.1, GDQH01023895.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced NP_001303918.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P2M5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042393 histone binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IFY9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IG59-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IG59_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IG59",
                "type": "external"
            }
        ],
        "mass": 26546.0,
        "length": 232,
        "protein_name": "Vesicle transport protein SEC20",
        "gene_name": "bnip1b",
        "organism": "Zebrafish",
        "refseq_name": "vesicle transport protein SEC20",
        "refseq_ac": [
            {
                "id": "XP_001333725",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333725",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bnip1b",
        "gene_names_refseq": "bnip1b",
        "protein_names_uniprotkb": "Vesicle transport protein SEC20",
        "protein_names_refseq": "vesicle transport protein SEC20",
        "tax_id": 7955,
        "disease": "Down syndrome (Disease Ontology:DOID:14250)",
        "pathway": " (dre:795732);  (R-DRE-6811434)",
        "pathway_count": 2,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_001333725.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1PRW9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0005484 SNAP receptor activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0031201 SNARE complex",
        "go_biological_process": "GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007029 endoplasmic reticulum organization",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IG59-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IGG5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IGG5",
                "type": "external"
            }
        ],
        "mass": 44345.0,
        "length": 398,
        "protein_name": "exo-alpha-sialidase",
        "gene_name": "neu3.5",
        "organism": "Zebrafish",
        "refseq_name": "sialidase 3 (membrane sialidase), tandem duplicate 5 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005161185",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161185",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "neu3.5; si:dkey-11j5.6",
        "gene_names_refseq": "neu3.5; si:dkey-11j5.6",
        "protein_names_uniprotkb": "exo-alpha-sialidase; 3.2.1.18",
        "protein_names_refseq": "sialidase 3 (membrane sialidase), tandem duplicate 5 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100000684)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "17708749;23032629;26469318;27189481;28252024;30405127;32686823;32980954",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2B816",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004308 exo-alpha-sialidase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005764 lysosome",
        "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0009313 oligosaccharide catabolic process;GO:0016042 lipid catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
        "record_id": "A0A0R4IGG5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IGG8-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IGG8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IGG8",
                "type": "external"
            }
        ],
        "mass": 76408.0,
        "length": 676,
        "protein_name": "ATP-binding cassette sub-family G member 8",
        "gene_name": "abcg8",
        "organism": "Zebrafish",
        "refseq_name": "ATP-binding cassette sub-family G member 8 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001108041",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108041",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "abcg8; zgc:172358",
        "gene_names_refseq": "abcg8; zgc:172358",
        "protein_names_uniprotkb": "ATP-binding cassette sub-family G member 8; Sterolin-2",
        "protein_names_refseq": "ATP-binding cassette sub-family G member 8 isoform 1; sterolin 2",
        "tax_id": 7955,
        "disease": "sitosterolemia 1 (Disease Ontology:DOID:0070634); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); sitosterolemia (Disease Ontology:DOID:0090019); familial hyperlipidemia (Disease Ontology:DOID:1168); cholestasis (Disease Ontology:DOID:13580); arteriosclerosis (Disease Ontology:DOID:2349); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dre:100136850)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16124856;16631343;19926124;25030662;26047617;28694436;32244031;32446740;33582286;34338990",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588726.28178818.1, SRR32588716.1270583.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476758 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Aug 4, 2025 this sequence version replaced XP_005156595.1, NP_001108041.2. Sequence Note:. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 7,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B2N0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity;GO:0042626 ATPase-coupled transmembrane transporter activity",
        "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005886 plasma membrane;GO:0043235 receptor complex",
        "go_biological_process": "GO:0006869 lipid transport;GO:0042632 cholesterol homeostasis;GO:0055085 transmembrane transport;GO:0033344 cholesterol efflux",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IGG8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IGK4-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IGK4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IGK4",
                "type": "external"
            }
        ],
        "mass": 34051.0,
        "length": 305,
        "protein_name": "Stomatin isoform X1",
        "gene_name": "stom",
        "organism": "Zebrafish",
        "refseq_name": "stomatin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017208322",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208322",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "stom; band7.2; band72; epb72; zgc:110814",
        "gene_names_refseq": "band7.2; band72; epb72; stom; zgc:110814",
        "protein_names_uniprotkb": "Stomatin isoform X1",
        "protein_names_refseq": "stomatin isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-2672351);  (R-DRE-6798695);  (R-DRE-8980692);  (R-DRE-9013026);  (R-DRE-9013106);  (R-DRE-9013148);  (R-DRE-9013406);  (R-DRE-9013407)",
        "pathway_count": 8,
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        "publication_id_list": "10207156;16109975;16466575;27189481;28252024;35226401;9537416",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M6Z3Q4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008200 ion channel inhibitor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IGT8-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IGT8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IGT8",
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            }
        ],
        "mass": 148438.0,
        "length": 1355,
        "protein_name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3",
        "gene_name": "magi3a",
        "organism": "Zebrafish",
        "refseq_name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001352122",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352122",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "magi3a; magi3; si:ch211-139k15.1; wu:fi36a10",
        "gene_names_refseq": "magi3a; magi3; si:ch211-139k15.1; wu:fi36a10",
        "protein_names_uniprotkb": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Membrane-associated guanylate kinase inverted 3",
        "protein_names_refseq": "membrane associated guanylate kinase, WW and PDZ domain containing 3; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3a isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:561689)",
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        "publication_id_list": "15520368;35649360",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025754.1, SRR26395013.471502.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001352122.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0A8M2B9B8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005923 bicellular tight junction",
        "go_biological_process": "GO:0007165 signal transduction",
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        "record_id": "A0A0R4IGT8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IGU0-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IGU0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IGU0",
                "type": "external"
            }
        ],
        "mass": 33209.0,
        "length": 296,
        "protein_name": "Calponin",
        "gene_name": "cnn1b",
        "organism": "Zebrafish",
        "refseq_name": "calponin-1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_701038",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_701038",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cnn1b",
        "gene_names_refseq": "cnn1b",
        "protein_names_uniprotkb": "Calponin",
        "protein_names_refseq": "calponin-1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:572250)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_701038.4. COMPLETENESS: full length., [RefSeq]; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8N7UVF7",
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        "go_molecular_function": "GO:0005516 calmodulin binding;GO:0051015 actin filament binding;GO:0003779 actin binding",
        "go_cellular_component": "GO:0015629 actin cytoskeleton",
        "go_biological_process": "GO:0007015 actin filament organization;GO:0031032 actomyosin structure organization",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IGU0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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            {
                "id": "A0A0R4IGV0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IGV0",
                "type": "external"
            }
        ],
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        "length": 518,
        "protein_name": "Uncharacterized protein LOC107988037 precursor",
        "gene_name": "ino80e; si:ch73-54f23.2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC107988037 precursor",
        "refseq_ac": [
            {
                "id": "NP_001315052",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315052",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ino80e; si:ch73-54f23.2; si:ch73-54f23.2; zgc:77312",
        "gene_names_refseq": "si:ch73-54f23.2",
        "protein_names_uniprotkb": "Uncharacterized protein LOC107988037 precursor",
        "protein_names_refseq": "uncharacterized protein LOC107988037 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:107988037);  (dre:402932);  (R-DRE-114608)",
        "pathway_count": 3,
        "publication_count": 5,
        "publication_id_list": "18442396;22566537;27189481;28934389;32196499",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01030284.1, GFIL01018157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_001315052.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P9Y8",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0031011 Ino80 complex",
        "go_biological_process": "GO:0006338 chromatin remodeling;GO:0007420 brain development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0A0R4IGV0-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IH35-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IH35_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IH35",
                "type": "external"
            }
        ],
        "mass": 78020.0,
        "length": 711,
        "protein_name": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial",
        "gene_name": "mccc1",
        "organism": "Zebrafish",
        "refseq_name": "methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_001038380",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038380",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mccc1; si:dkey-37m8.6; zgc:154106",
        "gene_names_refseq": "mccc1; si:dkey-37m8.6; zgc:154106",
        "protein_names_uniprotkb": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; 6.4.1.4",
        "protein_names_refseq": "methylcrotonoyl-CoA carboxylase 1 (alpha); methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)",
        "tax_id": 7955,
        "disease": "3-methylcrotonyl-CoA carboxylase 1 deficiency (Disease Ontology:DOID:0080579)",
        "pathway": " (dre:777632);  (R-DRE-196780);  (R-DRE-70895)",
        "pathway_count": 3,
        "publication_count": 4,
        "publication_id_list": "16530355;21839851;27189481;32344036",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC125958.1, GDQQ01003777.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On Jun 25, 2025 this sequence version replaced NP_001038380.1., [RefSeq]; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1N9L7",
        "ec_number_list": [
            {
                "id": "6.4.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.1",
                "type": "external"
            },
            {
                "id": "6.4.1.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.4",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004485 methylcrotonoyl-CoA carboxylase activity",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A0R4IH35-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IH70-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IH70_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IH70",
                "type": "external"
            }
        ],
        "mass": 52326.0,
        "length": 483,
        "protein_name": "Vasculin-like protein 1",
        "gene_name": "gpbp1l1",
        "organism": "Zebrafish",
        "refseq_name": "vasculin-like protein 1",
        "refseq_ac": [
            {
                "id": "XP_021332858",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332858",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gpbp1l1",
        "gene_names_refseq": "gpbp1l1",
        "protein_names_uniprotkb": "Vasculin-like protein 1",
        "protein_names_refseq": "vasculin-like protein 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:799876)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M9Q0P7;A0AC58JVC1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0003723 RNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IH76-1",
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            {
                "id": "A0A0R4IH76_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IH76",
                "type": "external"
            }
        ],
        "mass": 280477.0,
        "length": 2450,
        "protein_name": "Nuclear mitotic apparatus protein 1",
        "gene_name": "numa1",
        "organism": "Zebrafish",
        "refseq_name": "nuclear mitotic apparatus protein 1",
        "refseq_ac": [
            {
                "id": "NP_001316910",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316910",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "numa1; NuMA; fb44b02; wu:fb44b02",
        "gene_names_refseq": "NuMA; fb44b02; numa1; wu:fb44b02",
        "protein_names_uniprotkb": "Nuclear mitotic apparatus protein 1",
        "protein_names_refseq": "nuclear mitotic apparatus protein 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:572344)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "21074723;27189481;37867960",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01026284.1, SRR26395062.297272.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001316910.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P5E1",
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        "go_molecular_function": "GO:0051011 microtubule minus-end binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005938 cell cortex;GO:0005876 spindle microtubule",
        "go_biological_process": "GO:1902365 positive regulation of protein localization to spindle pole body;GO:0000132 establishment of mitotic spindle orientation",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IHD8-1",
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            {
                "id": "A0A0R4IHD8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IHD8",
                "type": "external"
            }
        ],
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        "length": 256,
        "protein_name": "Claudin-23",
        "gene_name": "cldn23.2",
        "organism": "Zebrafish",
        "refseq_name": "claudin-23",
        "refseq_ac": [
            {
                "id": "XP_068080024",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080024",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cldn23.2",
        "gene_names_refseq": "cldn23.2",
        "protein_names_uniprotkb": "Claudin-23",
        "protein_names_refseq": "claudin-23",
        "tax_id": 7955,
        "disease": "atopic dermatitis (Disease Ontology:DOID:3310)",
        "pathway": " (dre:567620)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2B1T1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005198 structural molecule activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRU6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRU6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRU6",
                "type": "external"
            }
        ],
        "mass": 84176.0,
        "length": 752,
        "protein_name": "Rho GTPase-activating protein 24",
        "gene_name": "arhgap24",
        "organism": "Zebrafish",
        "refseq_name": "rho GTPase-activating protein 24 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001339010",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339010",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "arhgap24",
        "gene_names_refseq": "arhgap24",
        "protein_names_uniprotkb": "Rho GTPase-activating protein 24; Rho-type GTPase-activating protein 24",
        "protein_names_refseq": "rho GTPase-activating protein 24 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100005116);  (R-DRE-8980692);  (R-DRE-9013148);  (R-DRE-9013149)",
        "pathway_count": 4,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001339010.1. COMPLETENESS: full length., [RefSeq]; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1PUP4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005096 GTPase activator activity",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0042995 cell projection",
        "go_biological_process": "GO:0007165 signal transduction;GO:0051056 regulation of small GTPase mediated signal transduction;GO:1900028 negative regulation of ruffle assembly;GO:0030154 cell differentiation;GO:0035313 wound healing, spreading of epidermal cells",
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        "record_id": "A0A0R4IRU6-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4II16-1",
        "uniprot_id": [
            {
                "id": "A0A0R4II16_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4II16",
                "type": "external"
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        ],
        "mass": 29747.0,
        "length": 272,
        "protein_name": "Proteasome inhibitor PI31 subunit",
        "gene_name": "psmf1",
        "organism": "Zebrafish",
        "refseq_name": "proteasome inhibitor PI31 subunit",
        "refseq_ac": [
            {
                "id": "NP_001002547",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002547",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "psmf1; zgc:92785",
        "gene_names_refseq": "psmf1; zgc:92785",
        "protein_names_uniprotkb": "Proteasome inhibitor PI31 subunit",
        "protein_names_refseq": "proteasome (prosome, macropain) inhibitor subunit 1; proteasome inhibitor PI31 subunit",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:436820)",
        "pathway_count": 1,
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        "publication_id_list": "15520368;22805612;23748566;26469318",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031653.1, EH473760.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505377, SAMEA3505378 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1, EH484771.1 and CD604800.1. On Jul 20, 2010 this sequence version replaced NP_001002547.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1N0P9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004866 endopeptidase inhibitor activity;GO:0070628 proteasome binding",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000502 proteasome complex",
        "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A0R4II16-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4II42-1",
        "uniprot_id": [
            {
                "id": "A0A0R4II42_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4II42",
                "type": "external"
            }
        ],
        "mass": 16222.0,
        "length": 140,
        "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 4",
        "gene_name": "uqcc4",
        "organism": "Zebrafish",
        "refseq_name": "ubiquinol-cytochrome c reductase complex assembly factor 4",
        "refseq_ac": [
            {
                "id": "NP_001373511",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373511",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "uqcc4; c24h16orf91; si:ch211-231f6.6",
        "gene_names_refseq": "c24h16orf91; si:ch211-231f6.6; uqcc4",
        "protein_names_uniprotkb": "Ubiquinol-cytochrome c reductase complex assembly factor 4",
        "protein_names_refseq": "ubiquinol-cytochrome c reductase complex assembly factor 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101882877)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01020675.1, EH528425.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476737, SAMEA4476748 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jun 25, 2025 this sequence version replaced NP_001373511.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2B9U8",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0022904 respiratory electron transport chain;GO:0034551 mitochondrial respiratory chain complex III assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A0R4II42-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IIB7-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IIB7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IIB7",
                "type": "external"
            }
        ],
        "mass": 56048.0,
        "length": 522,
        "protein_name": "Succinate-semialdehyde dehydrogenase",
        "gene_name": "aldh5a1",
        "organism": "Zebrafish",
        "refseq_name": "succinate-semialdehyde dehydrogenase, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290813",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290813",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "aldh5a1",
        "gene_names_refseq": "aldh5a1",
        "protein_names_uniprotkb": "Succinate-semialdehyde dehydrogenase; 1.2.1.24",
        "protein_names_refseq": "succinate-semialdehyde dehydrogenase, mitochondrial isoform X1",
        "tax_id": 7955,
        "disease": "succinic semialdehyde dehydrogenase deficiency (Disease Ontology:DOID:0060175); epilepsy (Disease Ontology:DOID:1826)",
        "pathway": " (dre:565235);  (R-DRE-916853)",
        "pathway_count": 2,
        "publication_count": 9,
        "publication_id_list": "18803863;20927131;22840776;28252024;31217350;32980661;35485397;38963759;39228401",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)., [UniProtKB, UniProtKB]",
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        ],
        "gene_names_uniprotkb": "foxq1a; foxq1l; zgc:162905",
        "gene_names_refseq": "foxq1a; foxq1l; zgc:162905",
        "protein_names_uniprotkb": "Forkhead box protein Q1a",
        "protein_names_refseq": "forkhead box protein Q1a",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100537750)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "20055451;26469318;27829009;29534099;31917260;33809683;33944782;34613771;36284357;36976966",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript is intronless :: GDQH01022231.1, BC093302.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1, EH435319.1 and EH461319.1. On Aug 12, 2011 this sequence version replaced XP_003197856.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; This study provides the first genetic mutant analyses of zebrafish foxq1a and foxq1b. Foxq1a, but not foxq1b, was transcriptionally regulated during a bacterial response, while the expression of foxq1a was detected in sorted macrophages and upregulated in foxq1a-deficient mutants. Publication Status: Online-Only, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P3Z1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0009410 response to xenobiotic stimulus;GO:0009888 tissue development;GO:0009653 anatomical structure morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IJS9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IJT4-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IJT4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IJT4",
                "type": "external"
            }
        ],
        "mass": 89600.0,
        "length": 794,
        "protein_name": "Phosphodiesterase",
        "gene_name": "pde10a",
        "organism": "Zebrafish",
        "refseq_name": "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",
        "refseq_ac": [
            {
                "id": "NP_957396",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957396",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pde10a; zgc:56689",
        "gene_names_refseq": "pde10a; zgc:56689",
        "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-",
        "protein_names_refseq": "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",
        "tax_id": 7955,
        "disease": "striatal degeneration 2 (Disease Ontology:DOID:0060998); traumatic brain injury (Disease Ontology:DOID:0081292)",
        "pathway": " (dre:394077)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "26469318;27189481;28252024;33221436",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC049532.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA4476748, SAMEA4476749 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 13, 2015 this sequence version replaced NP_957396.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PC69",
        "ec_number_list": [
            {
                "id": "3.1.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-",
                "type": "external"
            },
            {
                "id": "3.1.4.35",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.35",
                "type": "external"
            },
            {
                "id": "3.1.4.53",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0030552 cAMP binding;GO:0030553 cGMP binding;GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0007165 signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A0R4IJT4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IJU5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IJU5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IJU5",
                "type": "external"
            }
        ],
        "mass": 75392.0,
        "length": 695,
        "protein_name": "Synapsin-1",
        "gene_name": "syn2b",
        "organism": "Zebrafish",
        "refseq_name": "synapsin-2b",
        "refseq_ac": [
            {
                "id": "NP_001314700",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314700",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "syn2b; zgc:123199",
        "gene_names_refseq": "syn2b; zgc:123199",
        "protein_names_uniprotkb": "Synapsin-1; Synapsin I",
        "protein_names_refseq": "synapsin-2b",
        "tax_id": 7955,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); epilepsy (Disease Ontology:DOID:1826); schizophrenia (Disease Ontology:DOID:5419)",
        "pathway": " (dre:641578)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "20097902;23602570;24218366;25239370;26959078;27189481;29454044;30824836;35205114;39145297",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01040253.1, SRR32588727.637734.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 25, 2025 this sequence version replaced NP_001314700.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P900",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030672 synaptic vesicle membrane",
        "go_biological_process": "GO:0097091 synaptic vesicle clustering;GO:0050808 synapse organization;GO:0007269 neurotransmitter secretion",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IJU5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IJX1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IJX1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IJX1",
                "type": "external"
            }
        ],
        "mass": 73424.0,
        "length": 653,
        "protein_name": "FAST kinase domain-containing protein 3, mitochondrial isoform X1",
        "gene_name": "fastkd3",
        "organism": "Zebrafish",
        "refseq_name": "FAST kinase domain-containing protein 3, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001338251",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338251",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fastkd3",
        "gene_names_refseq": "fastkd3",
        "protein_names_uniprotkb": "FAST kinase domain-containing protein 3, mitochondrial isoform X1",
        "protein_names_refseq": "FAST kinase domain-containing protein 3, mitochondrial isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100003734)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PS97",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0035770 ribonucleoprotein granule",
        "go_biological_process": "GO:0000963 mitochondrial RNA processing;GO:0044528 regulation of mitochondrial mRNA stability",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IJX1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IJX9-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IJX9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IJX9",
                "type": "external"
            }
        ],
        "mass": 55561.0,
        "length": 498,
        "protein_name": "Peptidoglycan recognition protein 6",
        "gene_name": "pglyrp6",
        "organism": "Zebrafish",
        "refseq_name": "peptidoglycan recognition protein 6",
        "refseq_ac": [
            {
                "id": "NP_001038687",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038687",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pglyrp6",
        "gene_names_refseq": "pglyrp6",
        "protein_names_uniprotkb": "Peptidoglycan recognition protein 6",
        "protein_names_refseq": "peptidoglycan recognition protein 6; zfPGRP6",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 10,
        "publication_id_list": "16930467;17296228;17892854;18495251;20045065;25536407;28592872;30612570;31336107;36042265",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC171349.1, DQ447204.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476813, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC171349.1 and JBMGRA010000003.1. On Sep 2, 2015 this sequence version replaced NP_001038687.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; We identified and cloned three zebrafish Peptidoglycan recognition proteins, PGLYRP-2, PGLYRP-5, and PGLYRP-6, and showed that they are highly expressed in eggs, developing embryos, and adult tissues that contact external environment, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "total_o_glycosites": 0,
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        "total_s_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NA85;A0AC58IZ25",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008745 N-acetylmuramoyl-L-alanine amidase activity;GO:0008270 zinc ion binding;GO:0016019 peptidoglycan immune receptor activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0006955 immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0042742 defense response to bacterium;GO:0009253 peptidoglycan catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IJX9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IK06-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IK06_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IK06",
                "type": "external"
            }
        ],
        "mass": 127657.0,
        "length": 1167,
        "protein_name": "Rabankyrin-5 isoform X1",
        "gene_name": "ankfy1",
        "organism": "Zebrafish",
        "refseq_name": "rabankyrin-5",
        "refseq_ac": [
            {
                "id": "NP_001096142",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096142",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ankfy1; wu:fb69g03",
        "gene_names_refseq": "ankfy1; wu:fb69g03",
        "protein_names_uniprotkb": "Rabankyrin-5 isoform X1",
        "protein_names_refseq": "rabankyrin-5",
        "tax_id": 7955,
        "disease": "Charlevoix-Saguenay spastic ataxia (Disease Ontology:DOID:0050946)",
        "pathway": " (dre:568480)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "24683187;28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.15196084.1, SRR32588730.10947680.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505379, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On or before Jul 29, 2025 this sequence version replaced XP_005171962.1, NP_001096142.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "secondary_ac_list": "A0A8M2BJB2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031267 small GTPase binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0010008 endosome membrane",
        "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi;GO:0090160 Golgi to lysosome transport",
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        "kg_view_protein": true
    },
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        "uniprot_id": [
            {
                "id": "A0A0R4IK46_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IK46",
                "type": "external"
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        ],
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        "length": 339,
        "protein_name": "Protein FRA10AC1",
        "gene_name": "fra10ac1",
        "organism": "Zebrafish",
        "refseq_name": "protein FRA10AC1",
        "refseq_ac": [
            {
                "id": "NP_001006006",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006006",
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            }
        ],
        "gene_names_uniprotkb": "fra10ac1; fb96h04; fb96h10; fc62g03; rare; wu:fb96h04; wu:fb96h10; wu:fc62g03; zgc:103767",
        "gene_names_refseq": "fb96h04; fb96h10; fc62g03; fra10ac1; rare; wu:fb96h04; wu:fb96h10; wu:fc62g03; zgc:103767",
        "protein_names_uniprotkb": "Protein FRA10AC1",
        "protein_names_refseq": "fragile site, folic acid type, rare, candidate 1; protein FRA10AC1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:449836)",
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        "publication_id_list": "16109975",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01020306.1, BC083487.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1, CN508266.1 and AI588153.1. On Sep 1, 2015 this sequence version replaced NP_001006006.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
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        "go_molecular_function": "GO:0016791 phosphatase activity",
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        ],
        "mass": 175444.0,
        "length": 1540,
        "protein_name": "Mitogen-activated protein kinase kinase kinase 4",
        "gene_name": "map3k4",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase kinase kinase 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009305769",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305769",
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        "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 4; 2.7.11.25; MAPK/ERK kinase kinase 4",
        "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 4 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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                "id": "2.7.11.13",
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                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
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                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
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            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
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                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
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            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
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            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
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            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
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            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
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            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
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            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
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            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
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            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
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            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
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            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004709 MAP kinase kinase kinase activity;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm",
        "go_biological_process": "GO:0048263 determination of dorsal identity;GO:0038066 p38MAPK cascade",
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            {
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        ],
        "mass": 19052.0,
        "length": 163,
        "protein_name": "Interleukin",
        "gene_name": "il15l",
        "organism": "Zebrafish",
        "refseq_name": "interleukin 15, like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005157574",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157574",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "il15l; im:7142994; zgc:123044",
        "gene_names_refseq": "il15l; im:7142994; zgc:123044",
        "protein_names_uniprotkb": "Interleukin",
        "protein_names_refseq": "interleukin 15, like isoform X1",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "publication_id_list": "16055191;16919968;23434462;26391449;28111234;28300168;31822609;32784920",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding",
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        "mass": 93684.0,
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        "protein_name": "CSC1-like protein 2 isoform X1",
        "gene_name": "tmem63ba",
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        "refseq_name": "CSC1-like protein 2 isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157122",
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        ],
        "gene_names_uniprotkb": "tmem63ba",
        "gene_names_refseq": "tmem63ba",
        "protein_names_uniprotkb": "CSC1-like protein 2 isoform X1",
        "protein_names_refseq": "CSC1-like protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "developmental and epileptic encephalopathy 118 (Disease Ontology:DOID:0061176)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0016020 membrane",
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        "protein_name": "alanine transaminase",
        "gene_name": "si:ch211-217a12.1",
        "organism": "Zebrafish",
        "refseq_name": "alanine aminotransferase 2-like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001919896",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919896",
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        ],
        "gene_names_uniprotkb": "si:ch211-217a12.1",
        "gene_names_refseq": "si:ch211-217a12.1",
        "protein_names_uniprotkb": "alanine transaminase; 2.6.1.2; Glutamate pyruvate transaminase 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2",
        "protein_names_refseq": "alanine aminotransferase 2-like isoform X1",
        "tax_id": 7955,
        "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); obstructive jaundice (Disease Ontology:DOID:13603); acute kidney failure (Disease Ontology:DOID:3021); liver cancer (Disease Ontology:DOID:3571); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); amino acid metabolic disorder (Disease Ontology:DOID:9252); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452)",
        "pathway": " (dre:100148522)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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            {
                "id": "2.6.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.2",
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        ],
        "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
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            {
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        ],
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        "protein_name": "choline-phosphate cytidylyltransferase",
        "gene_name": "pcyt1bb",
        "organism": "Zebrafish",
        "refseq_name": "phosphate cytidylyltransferase 1B, choline b",
        "refseq_ac": [
            {
                "id": "NP_001032451",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032451",
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        ],
        "gene_names_uniprotkb": "pcyt1bb; zgc:123291",
        "gene_names_refseq": "pcyt1bb; zgc:123291",
        "protein_names_uniprotkb": "choline-phosphate cytidylyltransferase; 2.7.7.15",
        "protein_names_refseq": "phosphate cytidylyltransferase 1, choline, beta b; phosphate cytidylyltransferase 1B, choline b",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC109442.1, GDQH01009248.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505377, SAMEA3505380 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On or before Sep 16, 2025 this sequence version replaced XP_068071983.1, NP_001032451.1. Sequence Note:., [RefSeq]; Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis., [UniProtKB, UniProtKB]",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.15",
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            }
        ],
        "go_molecular_function": "GO:0004105 choline-phosphate cytidylyltransferase activity;GO:0031210 phosphatidylcholine binding",
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    {
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        "length": 403,
        "protein_name": "Transmembrane protein 200A isoform X1",
        "gene_name": "tmem200b",
        "organism": "Zebrafish",
        "refseq_name": "transmembrane protein 200A isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159619",
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        "protein_names_uniprotkb": "Transmembrane protein 200A isoform X1",
        "protein_names_refseq": "transmembrane protein 200A isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IKQ9",
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        ],
        "mass": 115318.0,
        "length": 1062,
        "protein_name": "Insulin receptor substrate 2",
        "gene_name": "irs2b",
        "organism": "Zebrafish",
        "refseq_name": "insulin receptor substrate 2",
        "refseq_ac": [
            {
                "id": "XP_700746",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700746",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "irs2b",
        "gene_names_refseq": "irs2b",
        "protein_names_uniprotkb": "Insulin receptor substrate 2",
        "protein_names_refseq": "insulin receptor substrate 2",
        "tax_id": 7955,
        "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dre:572001);  (R-DRE-109704);  (R-DRE-112399);  (R-DRE-112412);  (R-DRE-1257604);  (R-DRE-1266695);  (R-DRE-198203);  (R-DRE-5673001);  (R-DRE-6811558);  (R-DRE-74713);  (R-DRE-74749);  (R-DRE-8853659);  (R-DRE-9006335);  (R-DRE-9027276)",
        "pathway_count": 14,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_700746.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0035591 signaling adaptor activity;GO:0043548 phosphatidylinositol 3-kinase binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0008286 insulin receptor signaling pathway;GO:0051050 positive regulation of transport",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IKR8",
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        ],
        "mass": 120031.0,
        "length": 1065,
        "protein_name": "Huntingtin-interacting protein 1-related protein",
        "gene_name": "hip1rb",
        "organism": "Zebrafish",
        "refseq_name": "huntingtin interacting protein 1 related b",
        "refseq_ac": [
            {
                "id": "NP_001077034",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077034",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "hip1rb; hip1r; zgc:158784",
        "gene_names_refseq": "hip1rb; hip1r; zgc:158784",
        "protein_names_uniprotkb": "Huntingtin-interacting protein 1-related protein",
        "protein_names_refseq": "huntingtin interacting protein 1 related b",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:562138)",
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        "publication_id_list": "26377317;27189481",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC133158.1, SRR26395062.1102440.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On May 13, 2016 this sequence version replaced NP_001077034.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0051015 actin filament binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0035615 clathrin adaptor activity",
        "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0030659 cytoplasmic vesicle membrane;GO:0030136 clathrin-coated vesicle;GO:0030864 cortical actin cytoskeleton",
        "go_biological_process": "GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030100 regulation of endocytosis;GO:0061024 membrane organization",
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    {
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IL04",
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        ],
        "mass": 50424.0,
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        "protein_name": "Cyclic AMP-responsive element-binding protein 5",
        "gene_name": "creb5a",
        "organism": "Zebrafish",
        "refseq_name": "cyclic AMP-responsive element-binding protein 5",
        "refseq_ac": [
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        "gene_names_refseq": "creb5a",
        "protein_names_uniprotkb": "Cyclic AMP-responsive element-binding protein 5",
        "protein_names_refseq": "cyclic AMP-responsive element-binding protein 5",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to the cAMP response element and activates transcription., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0035497 cAMP response element binding",
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        "kg_view_protein": true
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    {
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            {
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        ],
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        "length": 397,
        "protein_name": "Uncharacterized protein LOC563864 precursor",
        "gene_name": "si:ch73-173h19.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC563864 precursor",
        "refseq_ac": [
            {
                "id": "NP_001103991",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103991",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-173h19.3",
        "gene_names_refseq": "si:ch73-173h19.3",
        "protein_names_uniprotkb": "Uncharacterized protein LOC563864 precursor",
        "protein_names_refseq": "EGF-containing fibulin-like extracellular matrix protein 1-like; uncharacterized protein LOC563864 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563864)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.13801542.1 [ECO:0000332] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Nov 16, 2007 this sequence version replaced XP_692315.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix",
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        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0A0R4IL24-1",
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            {
                "id": "A0A0R4IL24_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IL24",
                "type": "external"
            }
        ],
        "mass": 87235.0,
        "length": 762,
        "protein_name": "Coiled-coil alpha-helical rod protein 1",
        "gene_name": "cchcr1",
        "organism": "Zebrafish",
        "refseq_name": "coiled-coil alpha-helical rod protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_695620",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695620",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cchcr1; si:dkeyp-20g2.1",
        "gene_names_refseq": "si:dkeyp-20g2.1",
        "protein_names_uniprotkb": "Coiled-coil alpha-helical rod protein 1; Alpha-helical coiled-coil rod protein",
        "protein_names_refseq": "coiled-coil alpha-helical rod protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:567236)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_695620.1. COMPLETENESS: full length., [RefSeq]; May be a regulator of keratinocyte proliferation or differentiation., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005814 centriole",
        "go_biological_process": "GO:0030154 cell differentiation;GO:0006611 protein export from nucleus",
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        "kg_view_protein": true
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    {
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            {
                "id": "A0A0R4ILD9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ILD9",
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        ],
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        "length": 302,
        "protein_name": "Translation initiation factor eIF2B subunit alpha",
        "gene_name": "eif2b1",
        "organism": "Zebrafish",
        "refseq_name": "translation initiation factor eIF2B subunit alpha isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009300311",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300311",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "eif2b1; zgc:86660",
        "gene_names_refseq": "eif2b1; zgc:86660",
        "protein_names_uniprotkb": "Translation initiation factor eIF2B subunit alpha; eIF2B GDP-GTP exchange factor subunit alpha",
        "protein_names_refseq": "translation initiation factor eIF2B subunit alpha isoform X1",
        "tax_id": 7955,
        "disease": "leukoencephalopathy with vanishing white matter (Disease Ontology:DOID:0060868); leukoencephalopathy with vanishing white matter 1 (Disease Ontology:DOID:0070374)",
        "pathway": " (R-DRE-72731)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0003743 translation initiation factor activity",
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        "go_biological_process": "GO:0006413 translational initiation",
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        "kg_view_protein": true
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    {
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            {
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        ],
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        "protein_name": "FXYD domain-containing ion transport regulator",
        "gene_name": "fxyd2",
        "organism": "Zebrafish",
        "refseq_name": "sodium/potassium-transporting ATPase subunit gamma",
        "refseq_ac": [
            {
                "id": "NP_001268850",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268850",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fxyd2; si:ch211-139a5.9",
        "gene_names_refseq": "fxyd2; si:ch211-139a5.9",
        "protein_names_uniprotkb": "FXYD domain-containing ion transport regulator",
        "protein_names_refseq": "sodium/potassium-transporting ATPase subunit gamma",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-5578775);  (R-DRE-936837)",
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        "publication_id_list": "21423371;26469318;30417250;31113326",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH609708.1, EH592204.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505381, SAMEA3505387 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0017080 sodium channel regulator activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0006811 monoatomic ion transport;GO:1903278 positive regulation of sodium ion export across plasma membrane",
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        "record_id": "A0A0R4ILG2-1",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4ILM9",
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        ],
        "mass": 251968.0,
        "length": 2234,
        "protein_name": "Nucleolar pre-ribosomal-associated protein 1",
        "gene_name": "urb1",
        "organism": "Zebrafish",
        "refseq_name": "nucleolar pre-ribosomal-associated protein 1",
        "refseq_ac": [
            {
                "id": "NP_001313374",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313374",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "urb1; mp:zf637-1-000544",
        "gene_names_refseq": "mp:zf637-1-000544; urb1",
        "protein_names_uniprotkb": "Nucleolar pre-ribosomal-associated protein 1",
        "protein_names_refseq": "nucleolar pre-ribosomal-associated protein 1; zf637-1-000544",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100536352)",
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        "publication_id_list": "16109975;26469318;29246861;36403304;36890225;39178846",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007496.1, GFIL01019182.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_001313374.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance., [RefSeq, PubMed]; Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish, [RefSeq, PubMed]",
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        "secondary_ac_list": "A0A8M1P7Y6",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005730 nucleolus",
        "go_biological_process": "GO:0048565 digestive tract development;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0090069 regulation of ribosome biogenesis",
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        "kg_view_protein": true
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    {
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        ],
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        "protein_name": "Coiled-coil and C2 domain-containing protein 1B",
        "gene_name": "cc2d1b",
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        "refseq_name": "coiled-coil and C2 domain-containing protein 1B isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171255",
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        ],
        "gene_names_uniprotkb": "cc2d1b",
        "gene_names_refseq": "cc2d1b",
        "protein_names_uniprotkb": "Coiled-coil and C2 domain-containing protein 1B",
        "protein_names_refseq": "coiled-coil and C2 domain-containing protein 1B isoform X1",
        "tax_id": 7955,
        "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)",
        "pathway": " (dre:563720);  (R-DRE-9668328)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0005634 nucleus",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ILX8-1",
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            {
                "id": "A0A0R4ILX8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ILX8",
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        ],
        "mass": 54677.0,
        "length": 490,
        "protein_name": "Noelin-2b precursor",
        "gene_name": "olfm2b",
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            {
                "id": "NP_998425",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998425",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "olfm2b; olfm2l; zgc:85900",
        "gene_names_refseq": "olfm2b; olfm2l; zgc:85900",
        "protein_names_uniprotkb": "Noelin-2b precursor",
        "protein_names_refseq": "noelin-2b",
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        "publication_id_list": "20851470;27189481",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC068422.1, GFIL01029104.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA4476744 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 13, 2015 this sequence version replaced NP_998425.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0007165 signal transduction",
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IM59",
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        ],
        "mass": 305592.0,
        "length": 2780,
        "protein_name": "Neural-cadherin isoform X1",
        "gene_name": "si:dkey-22o22.2",
        "organism": "Zebrafish",
        "refseq_name": "neural-cadherin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001921123",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921123",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-22o22.2",
        "gene_names_refseq": "si:dkey-22o22.2",
        "protein_names_uniprotkb": "Neural-cadherin isoform X1",
        "protein_names_refseq": "neural-cadherin isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001921123.2. COMPLETENESS: full length., [RefSeq]; Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction",
        "go_biological_process": "GO:0007409 axonogenesis;GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0002009 morphogenesis of an epithelium;GO:0045216 cell-cell junction organization",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IMA9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IMA9",
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            }
        ],
        "mass": 49198.0,
        "length": 436,
        "protein_name": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1",
        "gene_name": "edil3a",
        "organism": "Zebrafish",
        "refseq_name": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001332616",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001332616",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "edil3a",
        "gene_names_refseq": "edil3a",
        "protein_names_uniprotkb": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1",
        "protein_names_refseq": "EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:793444)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_001332616.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
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        ],
        "mass": 23583.0,
        "length": 205,
        "protein_name": "Protein THEM6",
        "gene_name": "them6",
        "organism": "Zebrafish",
        "refseq_name": "Protein THEM6-like",
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            {
                "id": "NP_001116176",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116176",
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        "gene_names_uniprotkb": "them6; si:ch73-52e5.1; wu:fb81b06",
        "gene_names_refseq": "si:ch73-52e5.1; them6; wu:fb81b06",
        "protein_names_uniprotkb": "Protein THEM6",
        "protein_names_refseq": "Protein THEM6-like",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC124728.1, EH553650.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476769, SAMEA4476784 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On Mar 17, 2008 this sequence version replaced XP_698454.2., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "kg_view_protein": true
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                "type": "external"
            }
        ],
        "mass": 39093.0,
        "length": 333,
        "protein_name": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein",
        "gene_name": "snrnp48",
        "organism": "Zebrafish",
        "refseq_name": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein",
        "refseq_ac": [
            {
                "id": "NP_001108614",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108614",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "snrnp48; fd10a06; wu:fd10a06",
        "gene_names_refseq": "fd10a06; snrnp48; wu:fd10a06",
        "protein_names_uniprotkb": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein",
        "protein_names_refseq": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:325757)",
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        "publication_id_list": "16109975;29872546;39228401",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588721.3158493.1, SRR26395015.328131.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000016.1. On Mar 7, 2008 this sequence version replaced XP_699615.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1NI61",
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        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:1990904 ribonucleoprotein complex",
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        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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                "id": "A0A0R4IMS9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IMS9",
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            }
        ],
        "mass": 216818.0,
        "length": 1965,
        "protein_name": "DNA-directed RNA polymerase subunit",
        "gene_name": "polr2a",
        "organism": "Zebrafish",
        "refseq_name": "DNA-directed RNA polymerase II subunit RPB1",
        "refseq_ac": [
            {
                "id": "XP_005156282",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156282",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "polr2a",
        "gene_names_refseq": "polr2a",
        "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit; 2.7.7.6",
        "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB1",
        "tax_id": 7955,
        "disease": "chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
        "pathway": " (dre:553347);  (R-DRE-113418);  (R-DRE-674695);  (R-DRE-6781823);  (R-DRE-6782135);  (R-DRE-6782210);  (R-DRE-6796648);  (R-DRE-6803529);  (R-DRE-6807505);  (R-DRE-72086);  (R-DRE-72163);  (R-DRE-72165);  (R-DRE-72203);  (R-DRE-73776);  (R-DRE-73779);  (R-DRE-75953);  (R-DRE-75955);  (R-DRE-76042);  (R-DRE-77075);  (R-DRE-9018519);  (R-DRE-9770562)",
        "pathway_count": 21,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]; RNA-dependent RNA polymerase that catalyzes the extension of a non-coding RNA (ncRNA) at the 3'-end using the four ribonucleoside triphosphates as substrates. An internal ncRNA sequence near the 3'-end serves as a template in a single-round Pol II-mediated RNA polymerization reaction. May decrease the stability of ncRNAs that repress Pol II-mediated gene transcription., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 3,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 3,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B2W1",
        "ec_number_list": [
            {
                "id": "2.7.7.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6",
                "type": "external"
            },
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
            },
            {
                "id": "2.7.7.19",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19",
                "type": "external"
            },
            {
                "id": "5.2.1.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8",
                "type": "external"
            },
            {
                "id": "6.5.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
                "type": "external"
            },
            {
                "id": "2.7.1.78",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78",
                "type": "external"
            },
            {
                "id": "2.7.4.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.1.1.348",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.348",
                "type": "external"
            },
            {
                "id": "2.1.1.56",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.56",
                "type": "external"
            },
            {
                "id": "2.7.7.52",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52",
                "type": "external"
            },
            {
                "id": "3.1.27.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-",
                "type": "external"
            },
            {
                "id": "3.4.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-",
                "type": "external"
            },
            {
                "id": "5.6.2.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003968 RNA-directed RNA polymerase activity;GO:0003677 DNA binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0003899 DNA-directed RNA polymerase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0005665 RNA polymerase II, core complex",
        "go_biological_process": "GO:0042789 mRNA transcription by RNA polymerase II;GO:0006369 termination of RNA polymerase II transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IMS9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4IMW2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IMW2",
                "type": "external"
            }
        ],
        "mass": 25044.0,
        "length": 225,
        "protein_name": "2.1.1.319; Histone-arginine methyltransferase METTL23",
        "gene_name": "mettl23",
        "organism": "Zebrafish",
        "refseq_name": "histone-arginine methyltransferase METTL23",
        "refseq_ac": [
            {
                "id": "NP_001314968",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314968",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mettl23; ik:tdsubc_1b12; si:ch73-366l1.2; xx:tdsubc_1b12",
        "gene_names_refseq": "ik:tdsubc_1b12; mettl23; si:ch73-366l1.2; xx:tdsubc_1b12",
        "protein_names_uniprotkb": "2.1.1.319; Histone-arginine methyltransferase METTL23",
        "protein_names_refseq": "histone-arginine methyltransferase METTL23; methyltransferase like 23",
        "tax_id": 7955,
        "disease": "autosomal recessive intellectual developmental disorder 44 (Disease Ontology:DOID:0081208); glaucoma (Disease Ontology:DOID:1686)",
        "pathway": " (dre:337849)",
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        "publication_count": 1,
        "publication_id_list": "21873635",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01013214.1, SRR26395015.171374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1, EH544735.1, EH552856.1 and EH563165.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P9S6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0035642 histone H3R17 methyltransferase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0032259 methylation;GO:0040029 epigenetic regulation of gene expression",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IMY5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IMY5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IMY5",
                "type": "external"
            }
        ],
        "mass": 43229.0,
        "length": 387,
        "protein_name": "Testican-2",
        "gene_name": "spock3",
        "organism": "Zebrafish",
        "refseq_name": "testican-3 isoform a precursor",
        "refseq_ac": [
            {
                "id": "NP_001314916",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314916",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "spock3; im:7139568; si:dkey-285b22.1",
        "gene_names_refseq": "im:7139568; si:dkey-285b22.1; spock3",
        "protein_names_uniprotkb": "Testican-2; SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2",
        "protein_names_refseq": "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3; testican 3; testican-3 isoform a precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:562002)",
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        "publication_count": 5,
        "publication_id_list": "16545530;19308258;32430393;36127326;38381829",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC153904.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1, EH433753.1, EB939186.1, EH447295.1, EH458122.1 and EH468737.1. On Jun 1, 2016 this sequence version replaced XP_690495.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; May participate in diverse steps of neurogenesis. Binds calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P8M2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IMY5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IMZ8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IMZ8",
                "type": "external"
            }
        ],
        "mass": 97467.0,
        "length": 876,
        "protein_name": "Importin subunit beta-1",
        "gene_name": "kpnb1",
        "organism": "Zebrafish",
        "refseq_name": "importin subunit beta-1",
        "refseq_ac": [
            {
                "id": "NP_001032791",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032791",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "kpnb1; wu:fc12b10; zgc:123184",
        "gene_names_refseq": "kpnb1; wu:fc12b10; zgc:123184",
        "protein_names_uniprotkb": "Importin subunit beta-1",
        "protein_names_refseq": "importin subunit beta-1; karyopherin beta 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:570700);  (R-DRE-140342);  (R-DRE-1655829);  (R-DRE-2995383);  (R-DRE-6798695);  (R-DRE-68616);  (R-DRE-909733)",
        "pathway_count": 7,
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        "publication_id_list": "16109975;16616005;18086703;26553237;27189481;28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01002210.1, SRR32588715.1879154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Nov 19, 2014 this sequence version replaced NP_001032791.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N881",
        "ec_number_list": [],
        "go_molecular_function": "GO:0031267 small GTPase binding;GO:0008139 nuclear localization sequence binding;GO:0061608 nuclear import signal receptor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0048513 animal organ development;GO:0006606 protein import into nucleus",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A0R4IMZ8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IN44-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IN44_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IN44",
                "type": "external"
            }
        ],
        "mass": 59820.0,
        "length": 551,
        "protein_name": "PDZ and LIM domain protein 5a",
        "gene_name": "pdlim5a",
        "organism": "Zebrafish",
        "refseq_name": "PDZ and LIM domain protein 5a",
        "refseq_ac": [
            {
                "id": "NP_001002654",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002654",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pdlim5a; pdlim5; zgc:91978",
        "gene_names_refseq": "pdlim5a; pdlim5; zgc:91978",
        "protein_names_uniprotkb": "PDZ and LIM domain protein 5a",
        "protein_names_refseq": "DKEYP-100D11.1; ENH; PDZ and LIM domain 5; PDZ and LIM domain protein 5a",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); myofibrillar myopathy 4 (Disease Ontology:DOID:0080095); dilated cardiomyopathy (Disease Ontology:DOID:12930); myopathy (Disease Ontology:DOID:423)",
        "pathway": " (dre:436927)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "17937393;21966429;27189481;27806088",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC076551.1, SRR32588722.34943039.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jul 8, 2025 this sequence version replaced NP_001002654.2., [RefSeq]; Findings show the temporal & spatial expression patterns of the 3 Enigma family members & their PDZ & LIM domain encoding splice forms during embryogenesis, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "pathway": " (dre:405852);  (R-DRE-3214815);  (R-DRE-6804758);  (R-DRE-8943724);  (R-DRE-9937850);  (R-DRE-9940951)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002663014.1. COMPLETENESS: full length., [RefSeq]",
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                "url": "https://www.uniprot.org/uniprot/A0A0R4INS8",
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        ],
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        "length": 165,
        "protein_name": "Retinoic acid receptor responder 3",
        "gene_name": "rarres3",
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        "gene_names_refseq": "rarres3; zgc:154040",
        "protein_names_uniprotkb": "Retinoic acid receptor responder 3",
        "protein_names_refseq": "retinoic acid receptor responder 3",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH501496.1, BC124520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH501496.1, CK027983.1, EH525615.1 and EH518500.1. On Jun 17, 2015 this sequence version replaced NP_001070094.1., [RefSeq]",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC122119.1, SRR32588723.3840293.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505390 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. Sequence Note:., [RefSeq]",
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        "tax_id": 7955,
        "disease": "otitis media (Disease Ontology:DOID:10754); insulinoma (Disease Ontology:DOID:3892); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744)",
        "pathway": " (dre:503869);  (R-DRE-1227986);  (R-DRE-1236394);  (R-DRE-1250196);  (R-DRE-1250342);  (R-DRE-1250347);  (R-DRE-1257604);  (R-DRE-177929);  (R-DRE-179812);  (R-DRE-180292);  (R-DRE-180336);  (R-DRE-182971);  (R-DRE-1963640);  (R-DRE-1963642);  (R-DRE-212718);  (R-DRE-5673001);  (R-DRE-6785631);  (R-DRE-6811558);  (R-DRE-8847993);  (R-DRE-8863795)",
        "pathway_count": 20,
        "publication_count": 10,
        "publication_id_list": "19000772;19799903;20105326;21909574;22138660;26599586;27189481;27846271;31398318;37471641",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC075954.1, GFIL01045187.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_001038229.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells., [UniProtKB, UniProtKB]; These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "A0A8M2B857",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity;GO:0030297 transmembrane receptor protein tyrosine kinase activator activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0051781 positive regulation of cell division;GO:0045840 positive regulation of mitotic nuclear division",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4INZ6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IP03_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IP03",
                "type": "external"
            }
        ],
        "mass": 56930.0,
        "length": 499,
        "protein_name": "Cytochrome P450 2AA8",
        "gene_name": "cyp2aa8",
        "organism": "Zebrafish",
        "refseq_name": "cytochrome P450 2AA8",
        "refseq_ac": [
            {
                "id": "NP_001006080",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006080",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cyp2aa8; zgc:101673",
        "gene_names_refseq": "cyp2aa8; zgc:101673",
        "protein_names_uniprotkb": "Cytochrome P450 2AA8",
        "protein_names_refseq": "cytochrome P450 2AA8",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:450060);  (R-DRE-211935);  (R-DRE-211981);  (R-DRE-211999);  (R-DRE-9027307);  (R-DRE-9749641)",
        "pathway_count": 6,
        "publication_count": 10,
        "publication_id_list": "21087487;21116621;22297719;22931925;23726801;27189481;27444789;28411468;29259843;29725939",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01007948.1, BC083240.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001006080.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "secondary_ac_list": "A0A8M9PWG4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane",
        "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IS83_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS83",
                "type": "external"
            }
        ],
        "mass": 87516.0,
        "length": 797,
        "protein_name": "Periostin",
        "gene_name": "postnb",
        "organism": "Zebrafish",
        "refseq_name": "periostin, osteoblast specific factor b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290066",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290066",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "postnb; fa99h07; pn; postn; wu:fa99h07; wu:fc70f09; zgc:153873",
        "gene_names_refseq": "fa99h07; pn; postnb; postn; wu:fa99h07; wu:fc70f09; zgc:153873",
        "protein_names_uniprotkb": "Periostin; Osteoblast-specific factor 2",
        "protein_names_refseq": "periostin, osteoblast specific factor b isoform X1",
        "tax_id": 7955,
        "disease": "bone structure disease (Disease Ontology:DOID:0080010); aggressive periodontitis (Disease Ontology:DOID:1474); congestive heart failure (Disease Ontology:DOID:6000); abdominal aortic aneurysm (Disease Ontology:DOID:7693); chronic kidney disease (Disease Ontology:DOID:784); degenerative disc disease (Disease Ontology:DOID:90)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "A0A8M3AHK2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008201 heparin binding;GO:0050839 cell adhesion molecule binding",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005615 extracellular space;GO:0031012 extracellular matrix",
        "go_biological_process": "GO:0071307 cellular response to vitamin K;GO:0007155 cell adhesion;GO:0016203 muscle attachment;GO:0030198 extracellular matrix organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IS83-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IPJ5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IPJ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IPJ5",
                "type": "external"
            }
        ],
        "mass": 11147.0,
        "length": 97,
        "protein_name": "Chemokine (C-C motif) ligand 34b, duplicate 1 precursor",
        "gene_name": "ccl34b.1",
        "organism": "Zebrafish",
        "refseq_name": "chemokine (C-C motif) ligand 34b, duplicate 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001108526",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108526",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ccl34b.1; si:dkey-25o1.6",
        "gene_names_refseq": "ccl34b.1; si:dkey-25o1.6",
        "protein_names_uniprotkb": "Chemokine (C-C motif) ligand 34b, duplicate 1 precursor",
        "protein_names_refseq": "CCL-chr24m; CCL34ba; Dr22_WGA1631_1_283786; chemokine (C-C motif) ligand 34b, duplicate 1 precursor; chemokine CCL-C24m",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563952)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16365434;16697551;18482437;23145839;27189481;33208372;35111746;36122226;37196825;38771396",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH471624.1, EH445745.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jul 21, 2011 this sequence version replaced NP_001108526.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8N1TQT2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008009 chemokine activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0006955 immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IPJ5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IPL1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IPL1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IPL1",
                "type": "external"
            }
        ],
        "mass": 15027.0,
        "length": 140,
        "protein_name": "Profilin",
        "gene_name": "pfn2b",
        "organism": "Zebrafish",
        "refseq_name": "profilin-2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005174113",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174113",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pfn2b; pfn2; wu:fb01g08; wu:fb54f09; wu:fd58f06",
        "gene_names_refseq": "pfn2b; pfn2; wu:fb01g08; wu:fb54f09; wu:fd58f06",
        "protein_names_uniprotkb": "Profilin",
        "protein_names_refseq": "profilin-2 isoform X1",
        "tax_id": 7955,
        "disease": "membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); hepatocellular carcinoma (Disease Ontology:DOID:684)",
        "pathway": " (R-DRE-4086400);  (R-DRE-5663220)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2BLC7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton",
        "go_biological_process": "GO:0032233 positive regulation of actin filament bundle assembly;GO:0030036 actin cytoskeleton organization;GO:0030833 regulation of actin filament polymerization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IPL1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IPM5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IPM5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IPM5",
                "type": "external"
            }
        ],
        "mass": 29834.0,
        "length": 278,
        "protein_name": "Transcription factor Sp6 isoform X1",
        "gene_name": "sp6",
        "organism": "Zebrafish",
        "refseq_name": "transcription factor Sp6 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009294533",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294533",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sp6; zgc:77358",
        "gene_names_refseq": "sp6; zgc:77358",
        "protein_names_uniprotkb": "Transcription factor Sp6 isoform X1",
        "protein_names_refseq": "transcription factor Sp6 isoform X1",
        "tax_id": 7955,
        "disease": "amelogenesis imperfecta type 1K (Disease Ontology:DOID:0060945); amelogenesis imperfecta (Disease Ontology:DOID:2187)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4IPP3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IPP3",
                "type": "external"
            }
        ],
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        "length": 470,
        "protein_name": "Uncharacterized protein si:ch73-109d9.3",
        "gene_name": "si:ch73-109d9.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-109d9.3",
        "refseq_ac": [
            {
                "id": "XP_005160142",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160142",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-109d9.3",
        "gene_names_refseq": "si:ch73-109d9.3",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-109d9.3",
        "protein_names_refseq": "uncharacterized protein si:ch73-109d9.3",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101883524)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
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        "record_type": "protein",
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IPW5",
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        ],
        "mass": 63524.0,
        "length": 576,
        "protein_name": "Carboxylic ester hydrolase",
        "gene_name": "si:ch73-89b15.3",
        "organism": "Zebrafish",
        "refseq_name": "cAMP-regulated D2 protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002661384",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661384",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-89b15.3",
        "gene_names_refseq": "si:ch73-89b15.3",
        "protein_names_uniprotkb": "Carboxylic ester hydrolase; 3.1.1.-",
        "protein_names_refseq": "cAMP-regulated D2 protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002661384.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
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        "predicted_s_glycosites": 0,
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        "go_molecular_function": "GO:0004104 cholinesterase activity",
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    },
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IQ46",
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        ],
        "mass": 57145.0,
        "length": 501,
        "protein_name": "Cytochrome P450 2AA12",
        "gene_name": "cyp2aa12",
        "organism": "Zebrafish",
        "refseq_name": "cytochrome P450 2AA12",
        "refseq_ac": [
            {
                "id": "NP_001103171",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103171",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cyp2aa12; zgc:171945",
        "gene_names_refseq": "cyp2aa12; zgc:171945",
        "protein_names_uniprotkb": "Cytochrome P450 2AA12",
        "protein_names_refseq": "cytochrome P450 2AA12",
        "tax_id": 7955,
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        "pathway": " (dre:555510);  (R-DRE-211935);  (R-DRE-211981);  (R-DRE-211999);  (R-DRE-9027307);  (R-DRE-9749641)",
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        "publication_count": 10,
        "publication_id_list": "21087487;21116621;23711412;23726801;25424564;28193729;28411468;29376370;29725939;33396047",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC152006.1, SRR32588731.2173611.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505393, SAMEA4476771 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jul 8, 2025 this sequence version replaced NP_001103171.2. Sequence Note:. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0A0R4IQV4;A0A8M1NG29",
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        "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane",
        "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process",
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        "kg_view_protein": true
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IQ55",
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        ],
        "mass": 39203.0,
        "length": 361,
        "protein_name": "Porphobilinogen deaminase",
        "gene_name": "hmbsa",
        "organism": "Zebrafish",
        "refseq_name": "hydroxymethylbilane synthase a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005171873",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171873",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hmbsa; hmbs; zgc:64128",
        "gene_names_refseq": "hmbsa; hmbs; zgc:64128",
        "protein_names_uniprotkb": "Porphobilinogen deaminase; 2.5.1.61; Hydroxymethylbilane synthase",
        "protein_names_refseq": "hydroxymethylbilane synthase a isoform X1",
        "tax_id": 7955,
        "disease": "prostate carcinoma (Disease Ontology:DOID:10286); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); acute intermittent porphyria (Disease Ontology:DOID:3890); seminoma (Disease Ontology:DOID:4440)",
        "pathway": " (R-DRE-189451)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2BJ45",
        "ec_number_list": [
            {
                "id": "2.5.1.61",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.61",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004418 hydroxymethylbilane synthase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol",
        "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IQ55-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IQ63",
                "type": "external"
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        ],
        "mass": 57443.0,
        "length": 502,
        "protein_name": "Cytochrome P450 2K16",
        "gene_name": "cyp2k16",
        "organism": "Zebrafish",
        "refseq_name": "cytochrome P450 2K16",
        "refseq_ac": [
            {
                "id": "NP_001005963",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005963",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cyp2k16; si:ch211-155i15.2; zgc:101876",
        "gene_names_refseq": "cyp2k16; si:ch211-155i15.2; zgc:101876",
        "protein_names_uniprotkb": "Cytochrome P450 2K16",
        "protein_names_refseq": "cytochrome P450 2K16",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:449790)",
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        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC083304.1, GDQQ01006463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Aug 27, 2015 this sequence version replaced NP_001005963.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
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        "missing_score": 10000,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N2L4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006082 organic acid metabolic process;GO:0046222 aflatoxin metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IQ63-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IQI6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IQI6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IQI6",
                "type": "external"
            }
        ],
        "mass": 72453.0,
        "length": 654,
        "protein_name": "Zinc finger FYVE domain-containing protein 1 isoform X1",
        "gene_name": "si:ch211-11n16.2",
        "organism": "Zebrafish",
        "refseq_name": "zinc finger FYVE domain-containing protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_691596",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691596",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-11n16.2",
        "gene_names_refseq": "si:ch211-11n16.2",
        "protein_names_uniprotkb": "Zinc finger FYVE domain-containing protein 1 isoform X1",
        "protein_names_refseq": "zinc finger FYVE domain-containing protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_691596.5. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7UT50",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding",
        "go_cellular_component": "GO:0005811 lipid droplet",
        "go_biological_process": "GO:0140042 lipid droplet formation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IQI6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IQI7-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IQI7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IQI7",
                "type": "external"
            }
        ],
        "mass": 123906.0,
        "length": 1121,
        "protein_name": "AP-4 complex subunit epsilon",
        "gene_name": "ap4e1",
        "organism": "Zebrafish",
        "refseq_name": "AP-4 complex subunit epsilon-1",
        "refseq_ac": [
            {
                "id": "XP_699042",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699042",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ap4e1",
        "gene_names_refseq": "ap4e1",
        "protein_names_uniprotkb": "AP-4 complex subunit epsilon",
        "protein_names_refseq": "AP-4 complex subunit epsilon-1",
        "tax_id": 7955,
        "disease": "stuttering (Disease Ontology:DOID:0060243); hereditary spastic paraplegia 51 (Disease Ontology:DOID:0110803)",
        "pathway": " (dre:570467);  (R-DRE-432720)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_699042.1. COMPLETENESS: full length., [RefSeq]; Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 2,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7TFG6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0140312 cargo adaptor activity",
        "go_cellular_component": "GO:0012505 endomembrane system;GO:0030124 AP-4 adaptor complex",
        "go_biological_process": "GO:0006886 intracellular protein transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IQI7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IQQ3-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IQQ3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IQQ3",
                "type": "external"
            }
        ],
        "mass": 32221.0,
        "length": 278,
        "protein_name": "Centriole, cilia and spindle-associated protein",
        "gene_name": "ccsapa",
        "organism": "Zebrafish",
        "refseq_name": "centriole, cilia and spindle-associated protein",
        "refseq_ac": [
            {
                "id": "XP_005160215",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160215",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ccsapa",
        "gene_names_refseq": "ccsapa",
        "protein_names_uniprotkb": "Centriole, cilia and spindle-associated protein",
        "protein_names_refseq": "centriole, cilia and spindle-associated protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101883094)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B6X5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008017 microtubule binding",
        "go_cellular_component": "GO:0005819 spindle;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone",
        "go_biological_process": "GO:1901673 regulation of mitotic spindle assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IQQ3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IR31-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IR31_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IR31",
                "type": "external"
            }
        ],
        "mass": 28414.0,
        "length": 250,
        "protein_name": "Uncharacterized protein LOC103911540 precursor",
        "gene_name": "mhc2dhb",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC103911540 precursor",
        "refseq_ac": [
            {
                "id": "NP_001005943",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005943",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mhc2dhb; zgc:103700",
        "gene_names_refseq": "mhc2dhb; zgc:103700",
        "protein_names_uniprotkb": "Uncharacterized protein LOC103911540 precursor",
        "protein_names_refseq": "H-2 class II histocompatibility antigen, E-S beta chain-like; MHCII; uncharacterized protein LOC103911540 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:103911540);  (R-DRE-2132295)",
        "pathway_count": 2,
        "publication_count": 10,
        "publication_id_list": "25219565;25956722;26509227;27084059;27189481;31057394;31678534;32390373;34262881;37179373",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01045080.1, BC083466.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH452369.1, EH465241.1 and JBMGRA010000008.1. On or before Mar 29, 2018 this sequence version replaced XP_009302405.1, NP_001005943.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3BBY8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding",
        "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex",
        "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation;GO:0050778 positive regulation of immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IR31-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRA3-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRA3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRA3",
                "type": "external"
            }
        ],
        "mass": 21069.0,
        "length": 193,
        "protein_name": "Protein lin-28 homolog A",
        "gene_name": "lin28aa",
        "organism": "Zebrafish",
        "refseq_name": "protein lin-28 homolog A isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017206944",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206944",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lin28aa",
        "gene_names_refseq": "lin28aa",
        "protein_names_uniprotkb": "Protein lin-28 homolog A",
        "protein_names_refseq": "protein lin-28 homolog A isoform X1",
        "tax_id": 7955,
        "disease": "nephroblastoma (Disease Ontology:DOID:2154)",
        "pathway": " (dre:799825)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M6YSU1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0003723 RNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005791 rough endoplasmic reticulum;GO:0000932 P-body",
        "go_biological_process": "GO:0031054 pre-miRNA processing;GO:0031047 regulatory ncRNA-mediated gene silencing",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IRA3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRA8-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRA8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRA8",
                "type": "external"
            }
        ],
        "mass": 31702.0,
        "length": 277,
        "protein_name": "Uncharacterized protein LOC563286",
        "gene_name": "mhc2d8.35b2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC563286",
        "refseq_ac": [
            {
                "id": "NP_001074102",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074102",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mhc2d8.35b2; si:busm1-160c18.3; si:dkey-33b17.3; si:dz160c18.3; zgc:158775",
        "gene_names_refseq": "mhc2d8.35b2; si:busm1-160c18.3; si:dkey-33b17.3; si:dz160c18.3; zgc:158775",
        "protein_names_uniprotkb": "Uncharacterized protein LOC563286",
        "protein_names_refseq": "MHC class II; beta chain; uncharacterized protein LOC563286",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563286);  (R-DRE-2132295)",
        "pathway_count": 2,
        "publication_count": 5,
        "publication_id_list": "22805612;24279922;27189481;35134499;37179373",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC129443.1, GFIL01035288.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On or before Jun 4, 2016 this sequence version replaced XP_009302403.1, NP_001074102.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7UYL8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding",
        "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex",
        "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation;GO:0050778 positive regulation of immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0A0R4IRA8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRF0-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRF0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRF0",
                "type": "external"
            }
        ],
        "mass": 47039.0,
        "length": 402,
        "protein_name": "Tektin",
        "gene_name": "tekt1",
        "organism": "Zebrafish",
        "refseq_name": "tektin-1",
        "refseq_ac": [
            {
                "id": "NP_001007398",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007398",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tekt1; zgc:101797",
        "gene_names_refseq": "tekt1; zgc:101797",
        "protein_names_uniprotkb": "Tektin",
        "protein_names_refseq": "tektin-1",
        "tax_id": 7955,
        "disease": "ciliopathy (Disease Ontology:DOID:0060340)",
        "pathway": " (dre:492525)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "18335061;19011630;20937855;23144623;27357367;28738802;29121203;31513014",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC085442.1, GDQH01026266.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 28, 2024 this sequence version replaced NP_001007398.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "secondary_ac_list": "A0A8M3ASX1",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0015630 microtubule cytoskeleton;GO:0005930 axoneme",
        "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0060271 cilium assembly",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IRF0-1",
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        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRJ2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRJ2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRJ2",
                "type": "external"
            }
        ],
        "mass": 38433.0,
        "length": 339,
        "protein_name": "inorganic diphosphatase",
        "gene_name": "ppa2",
        "organism": "Zebrafish",
        "refseq_name": "inorganic pyrophosphatase 2, mitochondrial isoform X2",
        "refseq_ac": [
            {
                "id": "XP_005159941",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159941",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ppa2; zgc:77715",
        "gene_names_refseq": "ppa2; zgc:77715",
        "protein_names_uniprotkb": "inorganic diphosphatase; 3.6.1.1",
        "protein_names_refseq": "inorganic pyrophosphatase 2, mitochondrial isoform X2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:402961);  (R-DRE-379716);  (R-DRE-71737)",
        "pathway_count": 3,
        "publication_count": 3,
        "publication_id_list": "24396069;26469318;28252024",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2B720",
        "ec_number_list": [
            {
                "id": "3.6.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004427 inorganic diphosphate phosphatase activity",
        "go_cellular_component": "GO:0005739 mitochondrion;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006796 phosphate-containing compound metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IRJ2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRM6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRM6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRM6",
                "type": "external"
            }
        ],
        "mass": 14392.0,
        "length": 128,
        "protein_name": "Fatty acid binding protein 1-B.1",
        "gene_name": "fabp1b.2",
        "organism": "Zebrafish",
        "refseq_name": "fatty acid binding protein 1-B.1",
        "refseq_ac": [
            {
                "id": "XP_002663094",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663094",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fabp1b.2",
        "gene_names_refseq": "fabp1b.2",
        "protein_names_uniprotkb": "Fatty acid binding protein 1-B.1",
        "protein_names_refseq": "fatty acid binding protein 1-B.1",
        "tax_id": 7955,
        "disease": "hypertension (Disease Ontology:DOID:10763); IgA glomerulonephritis (Disease Ontology:DOID:2986)",
        "pathway": " (dre:100330224)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_002663094.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1RKB8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005504 fatty acid binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol",
        "go_biological_process": "GO:0015908 fatty acid transport;GO:0033993 response to lipid",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IRM6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRS1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRS1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRS1",
                "type": "external"
            }
        ],
        "mass": 48562.0,
        "length": 423,
        "protein_name": "AP-1 complex subunit mu-1",
        "gene_name": "ap1m1",
        "organism": "Zebrafish",
        "refseq_name": "AP-1 complex subunit mu-1",
        "refseq_ac": [
            {
                "id": "NP_001318056",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001318056",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ap1m1",
        "gene_names_refseq": "ap1m1",
        "protein_names_uniprotkb": "AP-1 complex subunit mu-1",
        "protein_names_refseq": "AP-1 complex subunit mu-1; adaptor-related protein complex 1, mu 1 subunit",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100330411);  (R-DRE-2132295);  (R-DRE-432720);  (R-DRE-6798695)",
        "pathway_count": 4,
        "publication_count": 4,
        "publication_id_list": "20652956;24123392;26469318;28557307",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019957.1, SRR26395063.820717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1P5E7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0035615 clathrin adaptor activity",
        "go_cellular_component": "GO:0005802 trans-Golgi network;GO:0030121 AP-1 adaptor complex",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007420 brain development;GO:0048565 digestive tract development;GO:0006896 Golgi to vacuole transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A0R4IRS1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRS4-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IRS4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRS4",
                "type": "external"
            }
        ],
        "mass": 65477.0,
        "length": 588,
        "protein_name": "Bifunctional polynucleotide phosphatase/kinase",
        "gene_name": "pnkp",
        "organism": "Zebrafish",
        "refseq_name": "bifunctional polynucleotide phosphatase/kinase isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005173439",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173439",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pnkp; fe48d04; wu:fe48d04; zgc:153084",
        "gene_names_refseq": "fe48d04; pnkp; wu:fe48d04; zgc:153084",
        "protein_names_uniprotkb": "Bifunctional polynucleotide phosphatase/kinase; 2.7.1.78; 3.1.3.32; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase",
        "protein_names_refseq": "bifunctional polynucleotide phosphatase/kinase isoform X1",
        "tax_id": 7955,
        "disease": "microcephaly, seizures, and developmental delay (Disease Ontology:DOID:0080457); ataxia-oculomotor apraxia 4 (Disease Ontology:DOID:0081383); Charcot-Marie-Tooth disease type 2B2 (Disease Ontology:DOID:0110179)",
        "pathway": " (R-DRE-5649702)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 3,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2BKP4",
        "ec_number_list": [
            {
                "id": "2.7.1.78",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78",
                "type": "external"
            },
            {
                "id": "3.1.3.32",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32",
                "type": "external"
            },
            {
                "id": "6.5.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "4.2.99.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0046403 polynucleotide 3'-phosphatase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break",
        "go_biological_process": "GO:0006281 DNA repair",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IRS4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IRV6-1",
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            {
                "id": "A0A0R4IRV6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRV6",
                "type": "external"
            }
        ],
        "mass": 37897.0,
        "length": 335,
        "protein_name": "Transcription factor AP-4 isoform X1",
        "gene_name": "tfap4",
        "organism": "Zebrafish",
        "refseq_name": "transcription factor AP-4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005168526",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168526",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tfap4",
        "gene_names_refseq": "tfap4",
        "protein_names_uniprotkb": "Transcription factor AP-4 isoform X1",
        "protein_names_refseq": "transcription factor AP-4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100318080)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
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        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4IRX2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IRX2",
                "type": "external"
            }
        ],
        "mass": 10773.0,
        "length": 94,
        "protein_name": "C-C motif chemokine",
        "gene_name": "ccl27a",
        "organism": "Zebrafish",
        "refseq_name": "C-C motif chemokine 27a isoform 2 precursor",
        "refseq_ac": [
            {
                "id": "NP_001315310",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315310",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ccl27a; ccl1; wu:fa96a04",
        "gene_names_refseq": "ccl1; ccl27a; wu:fa96a04",
        "protein_names_uniprotkb": "C-C motif chemokine",
        "protein_names_refseq": "C-C motif chemokine 27a isoform 2 precursor; CC chemokine 1; Dr18_WGA1436_1_236332; Dr8_WGA606_1_66363",
        "tax_id": 7955,
        "disease": "COVID-19 (Disease Ontology:DOID:0080600); asthma (Disease Ontology:DOID:2841); atopic dermatitis (Disease Ontology:DOID:3310)",
        "pathway": " (dre:30268)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16365434;16697551;18482437;18784347;19084604;26469318;26851375;29247975;29554508;29760055",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH445572.1, EH467394.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH452920.1 and EH445572.1. On Jun 16, 2016 this sequence version replaced XP_005166726.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "secondary_ac_list": "A0A8M1P9V0",
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        "go_molecular_function": "GO:0008009 chemokine activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0006955 immune response",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IRX2-1",
        "record_type": "protein",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IS19_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS19",
                "type": "external"
            }
        ],
        "mass": 94362.0,
        "length": 830,
        "protein_name": "SLIT and NTRK-like protein 6 precursor",
        "gene_name": "slitrk6",
        "organism": "Zebrafish",
        "refseq_name": "SLIT and NTRK-like protein 6 precursor",
        "refseq_ac": [
            {
                "id": "NP_001292482",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292482",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slitrk6; wu:fc18f06",
        "gene_names_refseq": "slitrk6; wu:fc18f06",
        "protein_names_uniprotkb": "SLIT and NTRK-like protein 6 precursor",
        "protein_names_refseq": "SLIT and NTRK-like protein 6 precursor; slit and trk like 6",
        "tax_id": 7955,
        "disease": "high myopia-sensorineural deafness syndrome (Disease Ontology:DOID:0111628)",
        "pathway": " (dre:324096)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "24123428;26492970",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01043565.1, GDQH01017447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Mar 18, 2015 this sequence version replaced XP_003197659.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P1A6",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0007409 axonogenesis;GO:0051965 positive regulation of synapse assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IS19-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IS21-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IS21_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS21",
                "type": "external"
            }
        ],
        "mass": 165020.0,
        "length": 1465,
        "protein_name": "Uncharacterized protein si:dkey-238i5.2 isoform X1",
        "gene_name": "si:dkey-238i5.2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-238i5.2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_003199551",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199551",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-238i5.2",
        "gene_names_refseq": "si:dkey-238i5.2",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-238i5.2 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:dkey-238i5.2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:321155)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003199551.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RNP3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0030864 cortical actin cytoskeleton;GO:0042995 cell projection",
        "go_biological_process": "GO:0030036 actin cytoskeleton organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IS21-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IS27-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IS27_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS27",
                "type": "external"
            }
        ],
        "mass": 93682.0,
        "length": 837,
        "protein_name": "Olfactory receptor CG6 precursor",
        "gene_name": "olfcg6",
        "organism": "Zebrafish",
        "refseq_name": "olfactory receptor CG6",
        "refseq_ac": [
            {
                "id": "NP_001153313",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153313",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "olfcg6; A12; Dr9-10; si:dkey-74e13.1; v2ra12",
        "gene_names_refseq": "A12; Dr9-10; olfcg6; si:dkey-74e13.1; v2ra12",
        "protein_names_uniprotkb": "Olfactory receptor CG6 precursor",
        "protein_names_refseq": "olfactory receptor CG6; sub 9_2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100149406)",
        "pathway_count": 1,
        "publication_count": 6,
        "publication_id_list": "16226854;17014738;17156446;26108469;29792162;31263779",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.2808682.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505382 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On May 8, 2009 this sequence version replaced XP_001919175.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NUI9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A0R4IS27-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IS41-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IS41_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS41",
                "type": "external"
            }
        ],
        "mass": 33732.0,
        "length": 294,
        "protein_name": "C2H2-type zinc finger protein",
        "gene_name": "si:ch211-241b2.4",
        "organism": "Zebrafish",
        "refseq_name": "C2H2-type zinc finger protein",
        "refseq_ac": [
            {
                "id": "NP_001373223",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373223",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-241b2.4",
        "gene_names_refseq": "si:ch211-241b2.4",
        "protein_names_uniprotkb": "C2H2-type zinc finger protein",
        "protein_names_refseq": "C2H2-type zinc finger protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100150909)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH539915.1, GFIL01036159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476776 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 18, 2020 this sequence version replaced XP_001922865.4., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1QLN9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A0R4IS41-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IS70-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IS70_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS70",
                "type": "external"
            }
        ],
        "mass": 34117.0,
        "length": 317,
        "protein_name": "Purine-rich element binding protein Ba",
        "gene_name": "purba",
        "organism": "Zebrafish",
        "refseq_name": "purine-rich element binding protein Ba",
        "refseq_ac": [
            {
                "id": "NP_001153631",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153631",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "purba; si:dkey-202n14.1",
        "gene_names_refseq": "purba; si:dkey-202n14.1",
        "protein_names_uniprotkb": "Purine-rich element binding protein Ba",
        "protein_names_refseq": "purine-rich element binding protein B-like; purine-rich element binding protein Ba",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:565233)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "26469318;27189481;28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript is intronless :: GFIL01023782.1, BC167481.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and BC167481.1. On Apr 30, 2026 this sequence version replaced NP_001122194.2., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NUK6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0032422 purine-rich negative regulatory element binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IS70-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IS85-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IS85_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IS85",
                "type": "external"
            }
        ],
        "mass": 19393.0,
        "length": 176,
        "protein_name": "Glucagon a isoform 1 precursor",
        "gene_name": "gcga",
        "organism": "Zebrafish",
        "refseq_name": "glucagon a isoform 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001258699",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258699",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gcga; gcg; glu; zgc:103616",
        "gene_names_refseq": "gcga; gcg; glu; zgc:103616",
        "protein_names_uniprotkb": "Glucagon a isoform 1 precursor",
        "protein_names_refseq": "GLP-1; glucagon a isoform 1 precursor",
        "tax_id": 7955,
        "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); prediabetes syndrome (Disease Ontology:DOID:11716)",
        "pathway": " (dre:494052)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "10495291;11161572;11477692;11900460;38732518;38944125;39040253;39075492;39528516;9972283",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011279.1, EH445427.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505388 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NZU1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0031769 glucagon receptor binding;GO:0005179 hormone activity",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0042594 response to starvation;GO:0003323 type B pancreatic cell development",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IS85-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ISE0-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ISE0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ISE0",
                "type": "external"
            }
        ],
        "mass": 85687.0,
        "length": 775,
        "protein_name": "Major intrinsically disordered Notch2-binding receptor 1-like",
        "gene_name": "minar1l",
        "organism": "Zebrafish",
        "refseq_name": "major intrinsically disordered Notch2-binding receptor 1-like",
        "refseq_ac": [
            {
                "id": "XP_009291713",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291713",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "minar1l",
        "gene_names_refseq": "minar1l",
        "protein_names_uniprotkb": "Major intrinsically disordered Notch2-binding receptor 1-like",
        "protein_names_refseq": "major intrinsically disordered Notch2-binding receptor 1-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_c_glycosites": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3AK97;A0AC58HWL3;A0AC58HWL8;A0AC58HWL9",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system",
        "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0032007 negative regulation of TOR signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ISE0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ISV1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ISV1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ISV1",
                "type": "external"
            }
        ],
        "mass": 219593.0,
        "length": 2025,
        "protein_name": "HEAT repeat-containing protein 5B",
        "gene_name": "heatr5b",
        "organism": "Zebrafish",
        "refseq_name": "HEAT repeat-containing protein 5B",
        "refseq_ac": [
            {
                "id": "XP_009305319",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305319",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "heatr5b",
        "gene_names_refseq": "heatr5b",
        "protein_names_uniprotkb": "HEAT repeat-containing protein 5B",
        "protein_names_refseq": "HEAT repeat-containing protein 5B",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:571772)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3AYT6",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0030136 clathrin-coated vesicle;GO:0030139 endocytic vesicle",
        "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0008104 intracellular protein localization;GO:0042147 retrograde transport, endosome to Golgi",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ISV1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ISV2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ISV2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ISV2",
                "type": "external"
            }
        ],
        "mass": 9953.0,
        "length": 87,
        "protein_name": "Eotaxin",
        "gene_name": "ccl39.2",
        "organism": "Zebrafish",
        "refseq_name": "chemokine CCL-CUj precursor",
        "refseq_ac": [
            {
                "id": "NP_001135739",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001135739",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ccl39.2",
        "gene_names_refseq": "ccl39.2; si:ch211-149o7.5",
        "protein_names_uniprotkb": "Eotaxin",
        "protein_names_refseq": "CCL-chr25p; CCL39ab; chemokine CCL-C25s; chemokine CCL-CUj precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100332947)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH533572.1, EH507419.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08196793, SAMN18715701 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Sep 17, 2025 this sequence version replaced XP_003201459.1, NP_001135739.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RJM9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0006955 immune response;GO:0030335 positive regulation of cell migration;GO:0007411 axon guidance;GO:0050930 induction of positive chemotaxis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ISV2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ISV4-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ISV4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ISV4",
                "type": "external"
            }
        ],
        "mass": 90925.0,
        "length": 802,
        "protein_name": "Anaphase-promoting complex subunit 2",
        "gene_name": "anapc2",
        "organism": "Zebrafish",
        "refseq_name": "anaphase-promoting complex subunit 2",
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            {
                "id": "NP_001243675",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243675",
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            }
        ],
        "gene_names_uniprotkb": "anapc2; si:ch73-203i15.5",
        "gene_names_refseq": "anapc2; si:ch73-203i15.5",
        "protein_names_uniprotkb": "Anaphase-promoting complex subunit 2; Cyclosome subunit 2",
        "protein_names_refseq": "anaphase-promoting complex subunit 2",
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        "disease": "aplastic anemia (Disease Ontology:DOID:12449); primary angle-closure glaucoma (Disease Ontology:DOID:1405); lung adenocarcinoma (Disease Ontology:DOID:3910); lung adenoma (Disease Ontology:DOID:5386); acute myeloid leukemia (Disease Ontology:DOID:9119)",
        "pathway": " (dre:100318335);  (R-DRE-141430);  (R-DRE-174048);  (R-DRE-174084);  (R-DRE-174154);  (R-DRE-174178);  (R-DRE-174184);  (R-DRE-176407);  (R-DRE-176408);  (R-DRE-176409);  (R-DRE-176412);  (R-DRE-179409);  (R-DRE-2467813);  (R-DRE-2559582);  (R-DRE-68867);  (R-DRE-69017);  (R-DRE-983168)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01020877.1, SRR26395028.1285125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001243675.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation., [UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005680 anaphase-promoting complex",
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        ],
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            {
                "id": "XP_009297383",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297383",
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        "pathway": " (dre:100334661);  (R-DRE-8854214);  (R-DRE-8875656)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Tumor necrosis factor receptor superfamily member 9b precursor",
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        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313387",
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        ],
        "gene_names_uniprotkb": "tnfrsf9b; tnfrsf9",
        "gene_names_refseq": "tnfrsf9b; tnfrsf9",
        "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 9b precursor",
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        "tax_id": 7955,
        "disease": "immunodeficiency 109 (Disease Ontology:DOID:0061078)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01036376.1, EE315494.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196788 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 18, 2016 this sequence version replaced XP_001923114.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        ],
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        "protein_name": "Uncharacterized protein si:ch211-286o17.1",
        "gene_name": "si:ch211-286o17.1",
        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662572",
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        ],
        "gene_names_uniprotkb": "si:ch211-286o17.1",
        "gene_names_refseq": "si:ch211-286o17.1",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-286o17.1",
        "protein_names_refseq": "uncharacterized protein si:ch211-286o17.1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IT71",
                "type": "external"
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        ],
        "mass": 119464.0,
        "length": 1077,
        "protein_name": "Folliculin-interacting protein 1",
        "gene_name": "fnip1",
        "organism": "Zebrafish",
        "refseq_name": "folliculin-interacting protein 1",
        "refseq_ac": [
            {
                "id": "NP_001120937",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120937",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fnip1; fc45f03; wu:fc45f03; zgc:175140",
        "gene_names_refseq": "fc45f03; fnip1; wu:fc45f03; zgc:175140",
        "protein_names_uniprotkb": "Folliculin-interacting protein 1",
        "protein_names_refseq": "folliculin-interacting protein 1-like; folliculin-interacting protein 1",
        "tax_id": 7955,
        "disease": "immunodeficiency 93 (Disease Ontology:DOID:0061063)",
        "pathway": " (dre:324863);  (R-DRE-9639288)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01046675.1, SRR26395039.43659.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On or before Feb 25, 2016 this sequence version replaced XP_005173972.2, NP_001120937.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by partial transcript alignments and orthologous alignments., [RefSeq]",
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        "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0042030 ATPase inhibitor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005765 lysosomal membrane",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IT98",
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        ],
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        "protein_name": "Chemerin-like receptor 2",
        "gene_name": "cmklr2",
        "organism": "Zebrafish",
        "refseq_name": "chemerin-like receptor 2",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001343514",
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        ],
        "gene_names_uniprotkb": "cmklr2",
        "gene_names_refseq": "cmklr2",
        "protein_names_uniprotkb": "Chemerin-like receptor 2",
        "protein_names_refseq": "chemerin-like receptor 2",
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        "pathway": " (dre:100004124);  (R-DRE-391908);  (R-DRE-418594)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001343514.1. COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0004875 complement receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0042923 neuropeptide binding",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection",
        "go_biological_process": "GO:0006935 chemotaxis;GO:0007218 neuropeptide signaling pathway",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4ITH7_DANRE",
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                "type": "external"
            }
        ],
        "mass": 68206.0,
        "length": 609,
        "protein_name": "poly(ADP-ribose) glycohydrolase",
        "gene_name": "pargl",
        "organism": "Zebrafish",
        "refseq_name": "poly(ADP-ribose) glycohydrolase",
        "refseq_ac": [
            {
                "id": "XP_001338257",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338257",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pargl",
        "gene_names_refseq": "pargl",
        "protein_names_uniprotkb": "poly(ADP-ribose) glycohydrolase; 3.2.1.143",
        "protein_names_refseq": "poly(ADP-ribose) glycohydrolase",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:797792)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001338257.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004649 poly(ADP-ribose) glycohydrolase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009225 nucleotide-sugar metabolic process;GO:0006282 regulation of DNA repair;GO:1990966 ATP generation from poly-ADP-D-ribose",
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    },
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                "url": "https://www.uniprot.org/uniprot/A0A0R4ITJ3",
                "type": "external"
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        ],
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        "length": 401,
        "protein_name": "Transcription factor SOX-8a isoform X1",
        "gene_name": "sox8a",
        "organism": "Zebrafish",
        "refseq_name": "transcription factor SOX-8a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017213911",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213911",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sox8a",
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        "protein_names_uniprotkb": "Transcription factor SOX-8a isoform X1",
        "protein_names_refseq": "transcription factor SOX-8a isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0014032 neural crest cell development;GO:0002009 morphogenesis of an epithelium",
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4ITL2",
                "type": "external"
            }
        ],
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        "length": 894,
        "protein_name": "Uncharacterized protein LOC553526",
        "gene_name": "ZCWCC3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC553526",
        "refseq_ac": [
            {
                "id": "NP_001307140",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307140",
                "type": "external"
            }
        ],
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        "gene_names_refseq": "ZCWCC3; zgc:152774",
        "protein_names_uniprotkb": "Uncharacterized protein LOC553526",
        "protein_names_refseq": "uncharacterized protein LOC553526",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01026643.1, SRR32588715.2807163.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505375, SAMEA3505381 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1, EH435650.1 and EH461649.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments, RNA-seq and orthologous alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M1P8M1",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0140002 histone H3K4me3 reader activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
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    },
    {
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            {
                "id": "A0A0R4ITN2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ITN2",
                "type": "external"
            }
        ],
        "mass": 51917.0,
        "length": 465,
        "protein_name": "Vitamin D-binding protein",
        "gene_name": "gc",
        "organism": "Zebrafish",
        "refseq_name": "vitamin D-binding protein precursor",
        "refseq_ac": [
            {
                "id": "NP_001002568",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002568",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gc; zgc:110389; zgc:92753",
        "gene_names_refseq": "gc; zgc:110389; zgc:92753",
        "protein_names_uniprotkb": "Vitamin D-binding protein; Gc-globulin; Group-specific component",
        "protein_names_refseq": "dbp; group-specific component (vitamin D binding protein); vitamin D-binding protein precursor",
        "tax_id": 7955,
        "disease": "primary progressive multiple sclerosis (Disease Ontology:DOID:0050784); pre-eclampsia (Disease Ontology:DOID:10591); sciatic neuropathy (Disease Ontology:DOID:11446); osteoporosis (Disease Ontology:DOID:11476); dengue disease (Disease Ontology:DOID:12205); Graves' disease (Disease Ontology:DOID:12361); neurodegenerative disease (Disease Ontology:DOID:1289); uveitis (Disease Ontology:DOID:13141); hepatic encephalopathy (Disease Ontology:DOID:13413); rheumatic fever (Disease Ontology:DOID:1586); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); endometriosis (Disease Ontology:DOID:289); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); arthritis (Disease Ontology:DOID:848); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 1 diabetes mellitus (Disease Ontology:DOID:9744)",
        "pathway": " (dre:436841);  (R-DRE-196791)",
        "pathway_count": 2,
        "publication_count": 10,
        "publication_id_list": "19200601;20471496;20653957;22440901;23515471;38029740;38747698;38961844;39110778;39209978",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC076230.1, GDQQ01036813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001002568.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "secondary_ac_list": "A0A8M1N0S6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0090482 vitamin transmembrane transporter activity;GO:0003779 actin binding;GO:0005499 vitamin D binding",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0042359 vitamin D metabolic process;GO:0031667 response to nutrient levels",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4ITN2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A0R4ITP7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ITP7",
                "type": "external"
            }
        ],
        "mass": 151557.0,
        "length": 1347,
        "protein_name": "Protein Shroom1",
        "gene_name": "shroom1",
        "organism": "Zebrafish",
        "refseq_name": "protein Shroom1",
        "refseq_ac": [
            {
                "id": "XP_687790",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687790",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "shroom1",
        "gene_names_refseq": "shroom1",
        "protein_names_uniprotkb": "Protein Shroom1",
        "protein_names_refseq": "protein Shroom1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:559364)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_687790.5. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8N7TET4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005874 microtubule;GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0030864 cortical actin cytoskeleton;GO:0043296 apical junction complex",
        "go_biological_process": "GO:0007015 actin filament organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0A0R4ITS1",
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            }
        ],
        "mass": 35188.0,
        "length": 319,
        "protein_name": "Uncharacterized protein si:ch211-215k15.4",
        "gene_name": "si:ch211-215k15.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-215k15.4",
        "refseq_ac": [
            {
                "id": "XP_021322670",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322670",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-215k15.4",
        "gene_names_refseq": "si:ch211-215k15.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-215k15.4",
        "protein_names_refseq": "uncharacterized protein si:ch211-215k15.4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:557984)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M9PN92",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0042806 fucose binding",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0001868 regulation of complement activation, lectin pathway;GO:0010185 regulation of cellular defense response",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4ITS1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4ITX2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4ITX2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4ITX2",
                "type": "external"
            }
        ],
        "mass": 70248.0,
        "length": 624,
        "protein_name": "2.7.11.25; Mitogen-activated protein kinase kinase kinase 22",
        "gene_name": "map3k22",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase kinase kinase 22",
        "refseq_ac": [
            {
                "id": "NP_001410597",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410597",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "map3k22; map3k20; zgc:171516",
        "gene_names_refseq": "map3k20; map3k22; zgc:171516",
        "protein_names_uniprotkb": "2.7.11.25; Mitogen-activated protein kinase kinase kinase 22",
        "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 20; mitogen-activated protein kinase kinase kinase 22",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100126011)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "20610484;22627281;26469318;27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01012438.1, GFIL01022085.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Aug 8, 2023 this sequence version replaced XP_005162724.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B9V2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004709 MAP kinase kinase kinase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0000165 MAPK cascade",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A0R4ITX2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IU39-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IU39_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IU39",
                "type": "external"
            }
        ],
        "mass": 54911.0,
        "length": 496,
        "protein_name": "Cell division cycle protein 20 homolog",
        "gene_name": "cdc20",
        "organism": "Zebrafish",
        "refseq_name": "cell division cycle protein 20 homolog",
        "refseq_ac": [
            {
                "id": "NP_998245",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998245",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cdc20; wu:fe49f10; zgc:63536; zombie; zom",
        "gene_names_refseq": "cdc20; wu:fe49f10; zgc:63536; zombie; zom",
        "protein_names_uniprotkb": "Cell division cycle protein 20 homolog",
        "protein_names_refseq": "cell division cycle protein 20 homolog",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:406353);  (R-DRE-141405);  (R-DRE-141430);  (R-DRE-141444);  (R-DRE-174048);  (R-DRE-174113);  (R-DRE-174154);  (R-DRE-174178);  (R-DRE-174184);  (R-DRE-176407);  (R-DRE-176408);  (R-DRE-176409);  (R-DRE-176417);  (R-DRE-179409);  (R-DRE-2467813);  (R-DRE-2500257);  (R-DRE-5663220);  (R-DRE-5689880);  (R-DRE-983168)",
        "pathway_count": 19,
        "publication_count": 10,
        "publication_id_list": "18629171;19092113;23968773;24083816;35641933;36334626;36846912;38242380;38960037;9007228",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC054907.1, GDQH01009056.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Apr 18, 2014 this sequence version replaced NP_998245.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3AX75",
        "ec_number_list": [],
        "go_molecular_function": "GO:0010997 anaphase-promoting complex binding;GO:1990757 ubiquitin ligase activator activity",
        "go_cellular_component": "GO:0005680 anaphase-promoting complex",
        "go_biological_process": "GO:0051301 cell division;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:1905786 positive regulation of anaphase-promoting complex-dependent catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IU39-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IU56-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IU56_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IU56",
                "type": "external"
            }
        ],
        "mass": 32159.0,
        "length": 288,
        "protein_name": "diphthine methyl ester synthase",
        "gene_name": "dph5",
        "organism": "Zebrafish",
        "refseq_name": "diphthine methyl ester synthase",
        "refseq_ac": [
            {
                "id": "NP_001007387",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007387",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "dph5; zgc:101823",
        "gene_names_refseq": "dph5; zgc:101823",
        "protein_names_uniprotkb": "diphthine methyl ester synthase; 2.1.1.314",
        "protein_names_refseq": "DPH5 homolog; diphthine methyl ester synthase",
        "tax_id": 7955,
        "disease": "neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties (Disease Ontology:DOID:0070479)",
        "pathway": " (dre:492514);  (R-DRE-5358493)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "27189481;38892048",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC085447.1, GDQQ01000297.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jun 25, 2025 this sequence version replaced NP_001007387.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N3B4",
        "ec_number_list": [
            {
                "id": "2.1.1.314",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.314",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004164 diphthine synthase activity;GO:0141133 diphthine methyl ester synthase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0032259 methylation;GO:0017183 protein histidyl modification to diphthamide",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IU56-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IUB6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IUB6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IUB6",
                "type": "external"
            }
        ],
        "mass": 67149.0,
        "length": 646,
        "protein_name": "Epsin-1",
        "gene_name": "epn1a",
        "organism": "Zebrafish",
        "refseq_name": "epsin-1",
        "refseq_ac": [
            {
                "id": "NP_001315045",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315045",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "epn1a; epn1; fd51f09; wu:fd51f09; wu:fj90e03; zgc:56381",
        "gene_names_refseq": "epn1a; epn1; fd51f09; wu:fd51f09; wu:fj90e03; zgc:56381",
        "protein_names_uniprotkb": "Epsin-1",
        "protein_names_refseq": "epsin 1; epsin-1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:406671)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "15520368;15621534;26469318;27189481;30408875",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01022546.1, SRR32588735.938166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_001315045.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 4,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 4,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 4,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P8T3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005543 phospholipid binding;GO:0030276 clathrin binding;GO:0008289 lipid binding",
        "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006897 endocytosis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0A0R4IUB6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IUH5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IUH5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IUH5",
                "type": "external"
            }
        ],
        "mass": 25766.0,
        "length": 235,
        "protein_name": "Synaptogyrin",
        "gene_name": "syngr2b",
        "organism": "Zebrafish",
        "refseq_name": "synaptogyrin-2b",
        "refseq_ac": [
            {
                "id": "NP_001076327",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076327",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "syngr2b; fj62c03; wu:fj62c03; zgc:162081",
        "gene_names_refseq": "fj62c03; syngr2b; wu:fj62c03; zgc:162081",
        "protein_names_uniprotkb": "Synaptogyrin",
        "protein_names_refseq": "synaptogyrin-2b",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:568509)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "12477932;21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH490282.1, BC133858.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505383 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH490282.1, EH547152.1, EH516632.1 and EH607122.1. On Feb 1, 2014 this sequence version replaced XP_696934.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M6YZL9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006355 regulation of DNA-templated transcription",
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        "hit_score": 0.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IV80-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IV80_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IV80",
                "type": "external"
            }
        ],
        "mass": 7904.0,
        "length": 69,
        "protein_name": "NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial",
        "gene_name": "ndufc1",
        "organism": "Zebrafish",
        "refseq_name": "NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_001268977",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268977",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ndufc1; si:ch211-235e9.6",
        "gene_names_refseq": "ndufc1; si:ch211-235e9.6",
        "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; Complex I-KFYI; NADH-ubiquinone oxidoreductase KFYI subunit",
        "protein_names_refseq": "LOC100000992oa; NADH dehydrogenase (ubiquinone) 1 subunit C1, mitochondria-like; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; TCONS_00023933",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100000992);  (R-DRE-611105);  (R-DRE-6799198)",
        "pathway_count": 3,
        "publication_count": 2,
        "publication_id_list": "28455512;38203224",
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        "function": "##Evidence-Data-START## Transcript exon combination :: CT636491.2, GFIL01014719.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476791 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH543676.1 and JBMGRA010000014.1., [RefSeq]; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P062",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I",
        "go_biological_process": "GO:0022904 respiratory electron transport chain",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IV80-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVE2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVE2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVE2",
                "type": "external"
            }
        ],
        "mass": 93705.0,
        "length": 865,
        "protein_name": "Ubiquitin carboxyl-terminal hydrolase",
        "gene_name": "usp10",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin carboxyl-terminal hydrolase 10 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_685621",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685621",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "usp10",
        "gene_names_refseq": "usp10",
        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12",
        "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 10 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564632);  (R-DRE-5656169);  (R-DRE-5689880)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_685621.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7UVN4",
        "ec_number_list": [
            {
                "id": "3.4.19.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            },
            {
                "id": "2.7.7.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0010506 regulation of autophagy;GO:0016579 protein deubiquitination;GO:0006914 autophagy",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IVE2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVM1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVM1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVM1",
                "type": "external"
            }
        ],
        "mass": 51362.0,
        "length": 479,
        "protein_name": "LSM14A mRNA processing body assembly factor b isoform X1",
        "gene_name": "lsm14ab",
        "organism": "Zebrafish",
        "refseq_name": "LSM14A mRNA processing body assembly factor b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005159030",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159030",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lsm14ab; wu:fc55d12; zgc:55754; zgc:77202",
        "gene_names_refseq": "lsm14ab; wu:fc55d12; zgc:55754; zgc:77202",
        "protein_names_uniprotkb": "LSM14A mRNA processing body assembly factor b isoform X1",
        "protein_names_refseq": "LSM14A mRNA processing body assembly factor b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
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        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2B5Y4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding",
        "go_cellular_component": "GO:0000932 P-body;GO:1990904 ribonucleoprotein complex;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0033962 P-body assembly;GO:0034063 stress granule assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IVM1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A286Y9R5-1",
        "uniprot_id": [
            {
                "id": "A0A286Y9R5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A286Y9R5",
                "type": "external"
            }
        ],
        "mass": 47210.0,
        "length": 431,
        "protein_name": "Zona pellucida sperm-binding protein 3",
        "gene_name": "LOC100536860; zp3.2",
        "organism": "Zebrafish",
        "refseq_name": "zona pellucida sperm-binding protein 3-like",
        "refseq_ac": [
            {
                "id": "XP_003200340",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200340",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100536860; zp3.2; zgc:171778; zp3.1",
        "gene_names_refseq": "LOC100536860",
        "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 3",
        "protein_names_refseq": "zona pellucida sperm-binding protein 3-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100148225);  (dre:100536860)",
        "pathway_count": 2,
        "publication_count": 5,
        "publication_id_list": "16481590;19299318;24051129;28399811;38177902",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RNX3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat;GO:0005615 extracellular space",
        "go_biological_process": "GO:2000344 positive regulation of acrosome reaction;GO:0035803 egg coat formation;GO:0007339 binding of sperm to zona pellucida",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0A286Y9R5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1NV16-1",
        "uniprot_id": [
            {
                "id": "A0A8M1NV16_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1NV16",
                "type": "external"
            }
        ],
        "mass": 308375.0,
        "length": 2794,
        "protein_name": "E3 ubiquitin-protein ligase UBR5",
        "gene_name": "ubr5",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase UBR5",
        "refseq_ac": [
            {
                "id": "NP_001157866",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157866",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ubr5; edd1; wu:fa16c12",
        "gene_names_refseq": "edd1; ubr5; wu:fa16c12",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase UBR5; 2.3.2.26; E3 ubiquitin-protein ligase, HECT domain-containing 1; Hyperplastic discs protein homolog",
        "protein_names_refseq": "E3 ubiquitin protein ligase, HECT domain containing, 1; E3 ubiquitin-protein ligase UBR5",
        "tax_id": 7955,
        "disease": "stomach cancer (Disease Ontology:DOID:10534); breast cancer (Disease Ontology:DOID:1612); colon cancer (Disease Ontology:DOID:219); colon adenocarcinoma (Disease Ontology:DOID:234); laryngeal carcinoma (Disease Ontology:DOID:2600); invasive ductal carcinoma (Disease Ontology:DOID:3008); gastric adenocarcinoma (Disease Ontology:DOID:3717); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); gallbladder carcinoma (Disease Ontology:DOID:4948)",
        "pathway": " (dre:334627)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "16109975;26436547;26469318;27046191;39021799",
        "class_list": "",
        "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000016.1. On Aug 22, 2009 this sequence version replaced XP_001923288.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0043130 ubiquitin binding;GO:0034450 ubiquitin-ubiquitin ligase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006281 DNA repair;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0000209 protein polyubiquitination",
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        "hit_score": 0.6,
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RTK1-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RTK1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RTK1",
                "type": "external"
            }
        ],
        "mass": 23941.0,
        "length": 215,
        "protein_name": "LHFPL tetraspan subfamily member 4 protein isoform X4",
        "gene_name": "lhfpl4a",
        "organism": "Zebrafish",
        "refseq_name": "LHFPL tetraspan subfamily member 4 protein isoform X4",
        "refseq_ac": [
            {
                "id": "XP_001922233",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922233",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lhfpl4a",
        "gene_names_refseq": "lhfpl4a",
        "protein_names_uniprotkb": "LHFPL tetraspan subfamily member 4 protein isoform X4",
        "protein_names_refseq": "LHFPL tetraspan subfamily member 4 protein isoform X4",
        "tax_id": 7955,
        "disease": "autosomal recessive nonsyndromic deafness 67 (Disease Ontology:DOID:0110518)",
        "pathway": " (dre:100151593)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001922233.1. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1QKQ9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0050811 GABA receptor binding",
        "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0045211 postsynaptic membrane;GO:0060077 inhibitory synapse",
        "go_biological_process": "GO:0097112 gamma-aminobutyric acid receptor clustering;GO:0007605 sensory perception of sound",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A2R8RTK1-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1P320-1",
        "uniprot_id": [
            {
                "id": "A0A8M1P320_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1P320",
                "type": "external"
            }
        ],
        "mass": 36024.0,
        "length": 325,
        "protein_name": "Sidoreflexin",
        "gene_name": "sfxn5a",
        "organism": "Zebrafish",
        "refseq_name": "sideroflexin-5a",
        "refseq_ac": [
            {
                "id": "NP_001230238",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230238",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sfxn5a; sfxn5; si:dkey-159c24.3",
        "gene_names_refseq": "sfxn5a; sfxn5; si:dkey-159c24.3",
        "protein_names_uniprotkb": "Sidoreflexin",
        "protein_names_refseq": "sideroflexin 5; sideroflexin-5a",
        "tax_id": 7955,
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        "pathway": " (dre:562654)",
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        "publication_count": 4,
        "publication_id_list": "27189481;33524530;35121025;37326485",
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0015075 monoatomic ion transmembrane transporter activity;GO:0015137 citrate transmembrane transporter activity",
        "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0006865 amino acid transport;GO:0015746 citrate transport;GO:1990542 mitochondrial transmembrane transport",
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        "kg_view_protein": true
    },
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            {
                "id": "A0A8M1P304_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1P304",
                "type": "external"
            }
        ],
        "mass": 31904.0,
        "length": 294,
        "protein_name": "Large ribosomal subunit protein uL2m",
        "gene_name": "mrpl2",
        "organism": "Zebrafish",
        "refseq_name": "large ribosomal subunit protein uL2m precursor",
        "refseq_ac": [
            {
                "id": "NP_001314714",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314714",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mrpl2; im:6908224",
        "gene_names_refseq": "im:6908224; mrpl2",
        "protein_names_uniprotkb": "Large ribosomal subunit protein uL2m; 39S ribosomal protein L2, mitochondrial",
        "protein_names_refseq": "large ribosomal subunit protein uL2m precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:571648);  (R-DRE-5389840);  (R-DRE-5419276);  (R-DRE-9937383)",
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        "publication_id_list": "26469318;27189481;27411634;28514663;30861003;38717324",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH543927.1, SRR26395039.180810.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN02418766 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1, EH543927.1 and EH565060.1. On May 25, 2016 this sequence version replaced XP_005173102.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
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        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "E7F8R3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0003723 RNA binding",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex;GO:0005762 mitochondrial large ribosomal subunit",
        "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation",
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        "kg_view_protein": true
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                "url": "https://www.uniprot.org/uniprot/A0A8M1P2D8",
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            }
        ],
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        "length": 2460,
        "protein_name": "Bromodomain adjacent to zinc finger domain protein 2A",
        "gene_name": "baz2a",
        "organism": "Zebrafish",
        "refseq_name": "bromodomain adjacent to zinc finger domain protein 2A isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001307060",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307060",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "baz2a; zgc:101601",
        "gene_names_refseq": "baz2a; zgc:101601",
        "protein_names_uniprotkb": "Bromodomain adjacent to zinc finger domain protein 2A",
        "protein_names_refseq": "bromodomain adjacent to zinc finger domain protein 2A isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:450079)",
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        "publication_id_list": "15520368;24240475;24683187;34315984",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.331512.1, SRR32588734.3323369.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Feb 12, 2016 this sequence version replaced XP_009294907.1., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0005634 nucleus;GO:0033553 rDNA heterochromatin",
        "go_biological_process": "GO:0006351 DNA-templated transcription",
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        "hit_score": 0.5,
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        "kg_view_protein": true
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    {
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                "id": "A0A8M1NZ19_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1NZ19",
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            }
        ],
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        "protein_name": "Centromere protein K",
        "gene_name": "cenpk",
        "organism": "Zebrafish",
        "refseq_name": "centromere protein K",
        "refseq_ac": [
            {
                "id": "NP_001243594",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243594",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cenpk; si:dkey-179o14.3",
        "gene_names_refseq": "cenpk; si:dkey-179o14.3",
        "protein_names_uniprotkb": "Centromere protein K",
        "protein_names_refseq": "SoxLZ/Sox6 leucine zipper binding protein; centromere protein K",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC151944.1, GFIL01003691.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 25, 2025 this sequence version replaced NP_001243594.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region",
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        "kg_view_protein": true
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                "url": "https://www.uniprot.org/uniprot/A0A8M1P3S1",
                "type": "external"
            }
        ],
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        "protein_name": "Interferon regulatory factor 2 isoform 1",
        "gene_name": "irf2b",
        "organism": "Zebrafish",
        "refseq_name": "interferon regulatory factor 2 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001315303",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315303",
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            }
        ],
        "gene_names_uniprotkb": "irf2b; irf2; zgc:103451",
        "gene_names_refseq": "irf2b; irf2; zgc:103451",
        "protein_names_uniprotkb": "Interferon regulatory factor 2 isoform 1",
        "protein_names_refseq": "interferon regulatory factor 2 isoform 1; interferon regulatory factor 2",
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        "publication_id_list": "19896215;20438850;21272652;24683187;25395663;32471880;33651979;35464458;35688336;36795566",
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        "function": "##Evidence-Data-START## Transcript exon combination :: CN506269.1, GFIL01013480.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0002376 immune system process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A8M1P3S1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8RHL8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RHL8",
                "type": "external"
            }
        ],
        "mass": 262088.0,
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        "protein_name": "2.7.11.1; Kalirin RhoGEF kinase b isoform 1",
        "gene_name": "kalrnb",
        "organism": "Zebrafish",
        "refseq_name": "kalirin RhoGEF kinase b isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001314918",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314918",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "kalrnb; wu:fc60a10; zgc:136817",
        "gene_names_refseq": "kalrnb; wu:fc60a10; zgc:136817",
        "protein_names_uniprotkb": "2.7.11.1; Kalirin RhoGEF kinase b isoform 1",
        "protein_names_refseq": "kalirin RhoGEF kinase b isoform 1",
        "tax_id": 7955,
        "disease": "cerebral atherosclerosis (Disease Ontology:DOID:12720); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526)",
        "pathway": " (R-DRE-193648);  (R-DRE-3928662);  (R-DRE-416476);  (R-DRE-416482);  (R-DRE-5687128);  (R-DRE-8980692);  (R-DRE-9013149);  (R-DRE-9013408)",
        "pathway_count": 8,
        "publication_count": 3,
        "publication_id_list": "20423468;25010335;25533206",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.1532418.1, SRR32588733.1053946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 25, 2025 this sequence version replaced NP_001314918.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
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        "reported_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P9D1",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0005524 ATP binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0019898 extrinsic component of membrane",
        "go_biological_process": "GO:0030097 hemopoiesis;GO:0035556 intracellular signal transduction;GO:0007411 axon guidance",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8QCZ8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QCZ8",
                "type": "external"
            }
        ],
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        "length": 1478,
        "protein_name": "Receptor-type tyrosine-protein phosphatase U",
        "gene_name": "ptprua",
        "organism": "Zebrafish",
        "refseq_name": "receptor-type tyrosine-protein phosphatase U-like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005159609",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159609",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ptprua",
        "gene_names_refseq": "ptprua",
        "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase U; 3.1.3.48; Receptor-type protein-tyrosine phosphatase psi",
        "protein_names_refseq": "receptor-type tyrosine-protein phosphatase U-like isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:563584)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B6M2",
        "ec_number_list": [
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            },
            {
                "id": "3.1.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2",
                "type": "external"
            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
                "type": "external"
            },
            {
                "id": "3.1.3.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27",
                "type": "external"
            },
            {
                "id": "3.1.3.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0070161 anchoring junction",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0030154 cell differentiation;GO:0007165 signal transduction;GO:0031175 neuron projection development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8QCZ8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N2F0-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N2F0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N2F0",
                "type": "external"
            }
        ],
        "mass": 25467.0,
        "length": 221,
        "protein_name": "DNA-directed RNA polymerase III subunit",
        "gene_name": "polr3gla",
        "organism": "Zebrafish",
        "refseq_name": "RNA polymerase III subunit GL a isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001004639",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004639",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "polr3gla; sb:cb265; zgc:101594",
        "gene_names_refseq": "polr3gla; sb:cb265; zgc:101594",
        "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit",
        "protein_names_refseq": "RNA polymerase III subunit GL a isoform 1; polymerase (RNA) III (DNA directed) polypeptide G like a",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:447901)",
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        "publication_id_list": "26469318;31940339",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC081380.1, CT698187.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081380.1. On Oct 1, 2011 this sequence version replaced NP_001004639.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from a transcript of a different strain than the reference genome strain because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005666 RNA polymerase III complex",
        "go_biological_process": "GO:0006383 transcription by RNA polymerase III",
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        "hit_score": 0.3,
        "record_id": "A0A8M1N2F0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8QN30_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QN30",
                "type": "external"
            }
        ],
        "mass": 24767.0,
        "length": 228,
        "protein_name": "Myelin protein P0 isoform X1",
        "gene_name": "mpz",
        "organism": "Zebrafish",
        "refseq_name": "myelin protein P0 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017213076",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213076",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mpz; p0; sc:d0186; wu:fc04b11; wu:fi30g06; zgc:103775",
        "gene_names_refseq": "mpz; p0; sc:d0186; wu:fc04b11; wu:fi30g06; zgc:103775",
        "protein_names_uniprotkb": "Myelin protein P0 isoform X1",
        "protein_names_refseq": "myelin protein P0 isoform X1",
        "tax_id": 7955,
        "disease": "Charcot-Marie-Tooth disease type 3 (Disease Ontology:DOID:0050540); PCWH syndrome (Disease Ontology:DOID:0090111); Charcot-Marie-Tooth disease type 1B (Disease Ontology:DOID:0110152); Charcot-Marie-Tooth disease type 2J (Disease Ontology:DOID:0110157); Charcot-Marie-Tooth disease type 2I (Disease Ontology:DOID:0110158); Charcot-Marie-Tooth disease dominant intermediate D (Disease Ontology:DOID:0110200); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); neuropathy (Disease Ontology:DOID:870)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M6Z8A8",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane;GO:0043209 myelin sheath;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0042552 myelination",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8QN30-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IXK5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IXK5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IXK5",
                "type": "external"
            }
        ],
        "mass": 8482.0,
        "length": 75,
        "protein_name": "Centromere protein W isoform 1",
        "gene_name": "cenpw",
        "organism": "Zebrafish",
        "refseq_name": "centromere protein W isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001313366",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313366",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cenpw; si:ch211-195p4.3",
        "gene_names_refseq": "cenpw; si:ch211-195p4.3",
        "protein_names_uniprotkb": "Centromere protein W isoform 1",
        "protein_names_refseq": "Cug2; centromere protein W isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:567320)",
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        "publication_id_list": "21838932;26469318",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01024015.1, EX159231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1 and EH509864.1. On May 18, 2016 this sequence version replaced XP_709181.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Cug2 is required for normal mitosis during early neurogenesis and has functions in neuronal cell maintenance Publication Status: Online-Only, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P2M9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000776 kinetochore;GO:0005634 nucleus",
        "go_biological_process": "GO:0051382 kinetochore assembly;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0007417 central nervous system development;GO:0007346 regulation of mitotic cell cycle",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IXK5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVN1-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVN1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVN1",
                "type": "external"
            }
        ],
        "mass": 19648.0,
        "length": 172,
        "protein_name": "Centrin-1",
        "gene_name": "cetn2",
        "organism": "Zebrafish",
        "refseq_name": "centrin-1",
        "refseq_ac": [
            {
                "id": "XP_001345066",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345066",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cetn2",
        "gene_names_refseq": "cetn2",
        "protein_names_uniprotkb": "Centrin-1",
        "protein_names_refseq": "centrin-1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100006257);  (R-DRE-3108214);  (R-DRE-380320);  (R-DRE-5696394);  (R-DRE-5696395);  (R-DRE-9646399)",
        "pathway_count": 6,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1PVB9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005814 centriole",
        "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0007099 centriole replication",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IVN1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVQ3-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVQ3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVQ3",
                "type": "external"
            }
        ],
        "mass": 40223.0,
        "length": 367,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "sc:d189",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC100002334 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001091730",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091730",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sc:d189",
        "gene_names_refseq": "sc:d189; sc:d816; si:dkey-151m22.6; zgc:172122",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein LOC100002334 isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC155607.1, CU458946.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Aug 21, 2025 this sequence version replaced NP_001091730.1., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_reported_s_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B3W3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0050776 regulation of immune response;GO:0043031 negative regulation of macrophage activation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IVQ3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVS5-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVS5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVS5",
                "type": "external"
            }
        ],
        "mass": 130906.0,
        "length": 1150,
        "protein_name": "Alpha-mannosidase",
        "gene_name": "man2a1",
        "organism": "Zebrafish",
        "refseq_name": "alpha-mannosidase 2",
        "refseq_ac": [
            {
                "id": "NP_001103497",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103497",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "man2a1; si:ch211-131c14.1",
        "gene_names_refseq": "man2a1; si:ch211-131c14.1",
        "protein_names_uniprotkb": "Alpha-mannosidase; 3.2.1.-",
        "protein_names_refseq": "alpha-mannosidase 2",
        "tax_id": 7955,
        "disease": "congenital dyserythropoietic anemia (Disease Ontology:DOID:1338); systemic lupus erythematosus (Disease Ontology:DOID:9074)",
        "pathway": " (dre:560219);  (R-DRE-975578)",
        "pathway_count": 2,
        "publication_count": 10,
        "publication_id_list": "20412557;21816947;24392132;25329564;26048245;27123470;27417116;28546340;30929901;33634099",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025774.1, GDQH01009036.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001103497.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1NG99",
        "ec_number_list": [
            {
                "id": "3.2.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004559 alpha-mannosidase activity;GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane",
        "go_biological_process": "GO:0006491 N-glycan processing;GO:0006013 mannose metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IVS5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVX3-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVX3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVX3",
                "type": "external"
            }
        ],
        "mass": 53067.0,
        "length": 483,
        "protein_name": "Homeobox protein unc-4 homolog",
        "gene_name": "uncx",
        "organism": "Zebrafish",
        "refseq_name": "homeobox protein unc-4 homolog",
        "refseq_ac": [
            {
                "id": "XP_005164261",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164261",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "uncx",
        "gene_names_refseq": "uncx",
        "protein_names_uniprotkb": "Homeobox protein unc-4 homolog",
        "protein_names_refseq": "homeobox protein unc-4 homolog",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:798510)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2BBD5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IVX3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IVY2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IVY2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IVY2",
                "type": "external"
            }
        ],
        "mass": 47233.0,
        "length": 436,
        "protein_name": "Uncharacterized protein LOC557028",
        "gene_name": "igf2bp2b",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC557028",
        "refseq_ac": [
            {
                "id": "NP_001082843",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082843",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "igf2bp2b; si:dkey-24b15.4; wu:fb81e12",
        "gene_names_refseq": "igf2bp2b; si:dkey-24b15.4; wu:fb81e12",
        "protein_names_uniprotkb": "Uncharacterized protein LOC557028",
        "protein_names_refseq": "uncharacterized protein LOC557028",
        "tax_id": 7955,
        "disease": "acquired metabolic disease (Disease Ontology:DOID:0060158); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dre:557028)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "18803835;26325373",
        "class_list": "",
        "function": "##Evidence-Data-START## CDS exon combination :: EU296399.1, EU296400.1 [ECO:0000331] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from BX088533.9. On May 24, 2007 this sequence version replaced XP_683723.2., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M6Z590",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0003723 RNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule",
        "go_biological_process": "GO:0070934 CRD-mediated mRNA stabilization;GO:0007399 nervous system development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IVY2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IVY9",
                "type": "external"
            }
        ],
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        "length": 725,
        "protein_name": "Centrosomal protein of 83 kDa",
        "gene_name": "cep83",
        "organism": "Zebrafish",
        "refseq_name": "centrosomal protein of 83 kDa",
        "refseq_ac": [
            {
                "id": "NP_001340860",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001340860",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cep83; ccdc41",
        "gene_names_refseq": "ccdc41; cep83",
        "protein_names_uniprotkb": "Centrosomal protein of 83 kDa",
        "protein_names_refseq": "centrosomal protein of 83 kDa; coiled-coil domain containing 41; coiled-coil domain-containing protein 41",
        "tax_id": 7955,
        "disease": "nephronophthisis 18 (Disease Ontology:DOID:0111125)",
        "pathway": " (dre:100007472)",
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        "publication_id_list": "23530209;27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01003243.1, SRR32588714.16810722.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jul 29, 2017 this sequence version replaced XP_009298702.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; CCDC41 is required for the docking of ciliary vesicles, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "reported_mutagensis": 0,
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        "go_cellular_component": "GO:0005813 centrosome",
        "go_biological_process": "GO:0060271 cilium assembly",
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        "kg_view_protein": true
    },
    {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IVZ0",
                "type": "external"
            }
        ],
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        "length": 1436,
        "protein_name": "Nuclear pore complex protein Nup153",
        "gene_name": "nup153",
        "organism": "Zebrafish",
        "refseq_name": "nuclear pore complex protein Nup153",
        "refseq_ac": [
            {
                "id": "NP_001313313",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313313",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nup153; fd23d09; si:ch211-153f2.5; wu:fd23d09",
        "gene_names_refseq": "fd23d09; nup153; si:ch211-153f2.5; wu:fd23d09",
        "protein_names_uniprotkb": "Nuclear pore complex protein Nup153; 153 kDa nucleoporin; Nucleoporin Nup153",
        "protein_names_refseq": "nuclear pore complex protein Nup153",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:571621);  (R-DRE-159227);  (R-DRE-159231);  (R-DRE-159236);  (R-DRE-1855170);  (R-DRE-1855196);  (R-DRE-1855229);  (R-DRE-191859);  (R-DRE-3108214);  (R-DRE-3232142);  (R-DRE-3301854);  (R-DRE-3371453);  (R-DRE-4551638)",
        "pathway_count": 13,
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        "publication_id_list": "15520368;26221075;27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01028940.1, SRR26395012.1245896.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On May 17, 2016 this sequence version replaced XP_005159852.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 10,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 10,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding",
        "go_cellular_component": "GO:0005643 nuclear pore;GO:0031965 nuclear membrane",
        "go_biological_process": "GO:0001525 angiogenesis;GO:0051028 mRNA transport;GO:0006405 RNA export from nucleus;GO:0006606 protein import into nucleus;GO:0015031 protein transport",
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        "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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            }
        ],
        "mass": 80265.0,
        "length": 688,
        "protein_name": "G-protein coupled receptor-associated protein LMBRD2a isoform 1",
        "gene_name": "lmbrd2a",
        "organism": "Zebrafish",
        "refseq_name": "G-protein coupled receptor-associated protein LMBRD2a isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001314843",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314843",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lmbrd2a; lmbrd2; zgc:110095",
        "gene_names_refseq": "lmbrd2a; lmbrd2; zgc:110095",
        "protein_names_uniprotkb": "G-protein coupled receptor-associated protein LMBRD2a isoform 1",
        "protein_names_refseq": "G-protein coupled receptor-associated protein LMBRD2a isoform 1; LMBR1 domain containing 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:550238)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "12477932;21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01014551.1, SRR32588733.1710788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jul 8, 2025 this sequence version replaced NP_001314843.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0016020 membrane",
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        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A2R8QTX4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QTX4",
                "type": "external"
            }
        ],
        "mass": 39943.0,
        "length": 360,
        "protein_name": "ELAV-like protein",
        "gene_name": "elavl1b",
        "organism": "Zebrafish",
        "refseq_name": "ELAV-like protein 1b isoform a",
        "refseq_ac": [
            {
                "id": "NP_570984",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570984",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "elavl1b; fb72d01; fk65g02; hug; wu:fb72d01; wu:fk65g02",
        "gene_names_refseq": "elavl1b; fb72d01; fk65g02; hug; wu:fb72d01; wu:fk65g02",
        "protein_names_uniprotkb": "ELAV-like protein",
        "protein_names_refseq": "ELAV-like protein 1b isoform a; etID19626.11",
        "tax_id": 7955,
        "disease": "degenerative disc disease (Disease Ontology:DOID:90)",
        "pathway": " (dre:30065)",
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        "publication_id_list": "16109975;21337467;24425803;26116573;28252024;31227602",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.977266.1, SRR26395012.552469.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505389, SAMEA3505392 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 14, 2015 this sequence version replaced NP_570984.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0140517 protein-RNA adaptor activity",
        "go_cellular_component": "GO:1990904 ribonucleoprotein complex;GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0070935 3'-UTR-mediated mRNA stabilization",
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        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IWG0",
                "type": "external"
            }
        ],
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        "protein_name": "Epigen precursor",
        "gene_name": "epgn",
        "organism": "Zebrafish",
        "refseq_name": "epigen precursor",
        "refseq_ac": [
            {
                "id": "NP_001373613",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373613",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "epgn",
        "gene_names_refseq": "epgn",
        "protein_names_uniprotkb": "Epigen precursor",
        "protein_names_refseq": "epigen precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100005297);  (R-DRE-1257604);  (R-DRE-177929);  (R-DRE-179812);  (R-DRE-180292);  (R-DRE-180336);  (R-DRE-182971);  (R-DRE-212718);  (R-DRE-5673001);  (R-DRE-6811558)",
        "pathway_count": 10,
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        "publication_id_list": "20105326;27189481;27846271",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01010347.1, GDQQ01046765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Mar 1, 2023 this sequence version replaced XP_001344391.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1PZS8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane",
        "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0045840 positive regulation of mitotic nuclear division",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IWG0-1",
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        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IWN8",
                "type": "external"
            }
        ],
        "mass": 10121.0,
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        "protein_name": "Non-histone chromosomal protein HMG-14A-like",
        "gene_name": "hmgn1a",
        "organism": "Zebrafish",
        "refseq_name": "Non-histone chromosomal protein HMG-14A-like",
        "refseq_ac": [
            {
                "id": "NP_001296573",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296573",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hmgn1a; linc-wrb; si:ch73-281n10.2; wu:fa95c02; wu:fb74d02",
        "gene_names_refseq": "hmgn1a; linc-wrb; si:ch73-281n10.2; wu:fa95c02; wu:fb74d02",
        "protein_names_uniprotkb": "Non-histone chromosomal protein HMG-14A-like",
        "protein_names_refseq": "Non-histone chromosomal protein HMG-14A-like; non-histone chromosomal protein HMG-17",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:561719)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "11116087;24705786;26593130;27189481;37191016",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC142830.1, CO914508.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, EH450941.1, EH523724.1, EH557609.1 and EH463221.1. On Jul 12, 2016 this sequence version replaced XP_005169755.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "go_molecular_function": "GO:0003682 chromatin binding;GO:0031492 nucleosomal DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin",
        "go_biological_process": "GO:0006325 chromatin organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0A0R4IWN8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IWV6-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IWV6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IWV6",
                "type": "external"
            }
        ],
        "mass": 38512.0,
        "length": 334,
        "protein_name": "G protein-coupled receptor 184",
        "gene_name": "gpr184",
        "organism": "Zebrafish",
        "refseq_name": "G protein-coupled receptor 184",
        "refseq_ac": [
            {
                "id": "NP_001296782",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296782",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gpr184; zgc:152692",
        "gene_names_refseq": "gpr184; zgc:152692",
        "protein_names_uniprotkb": "G protein-coupled receptor 184",
        "protein_names_refseq": "G protein-coupled receptor 184",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-373076);  (R-DRE-416476)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "21873635;31064998",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.29552701.1, SRR32588732.33298432.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Jul 24, 2025 this sequence version replaced XP_073779386.1, NP_001070177.1, XP_009289798.1. Sequence Note:., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P6S8;A0AC58HBN1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
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        "record_id": "A0A0R4IWV6-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IX00-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IX00_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IX00",
                "type": "external"
            }
        ],
        "mass": 62591.0,
        "length": 573,
        "protein_name": "Uncharacterized protein si:ch1073-224n8.1",
        "gene_name": "si:ch1073-224n8.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch1073-224n8.1",
        "refseq_ac": [
            {
                "id": "XP_001921563",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921563",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch1073-224n8.1",
        "gene_names_refseq": "si:ch1073-224n8.1",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch1073-224n8.1",
        "protein_names_refseq": "uncharacterized protein si:ch1073-224n8.1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:327438);  (R-DRE-9843940)",
        "pathway_count": 2,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1QV16",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A0R4IX00-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IX64-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IX64_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IX64",
                "type": "external"
            }
        ],
        "mass": 73492.0,
        "length": 679,
        "protein_name": "Uncharacterized protein lratb.1 isoform X1",
        "gene_name": "lratb.1",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "lratb.1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Uncharacterized protein lratb.1 isoform X1",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "Leber congenital amaurosis 14 (Disease Ontology:DOID:0110188); retinitis pigmentosa (Disease Ontology:DOID:10584)",
        "pathway": " (dre:553501);  (R-DRE-2453902);  (R-DRE-975634)",
        "pathway_count": 3,
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        "class_list": "",
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        "secondary_ac_list": "A0A8M3B744",
        "ec_number_list": [],
        "go_molecular_function": "GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity",
        "go_cellular_component": "GO:0005791 rough endoplasmic reticulum",
        "go_biological_process": "GO:0042572 retinol metabolic process;GO:0006776 vitamin A metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IX64-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IXA2-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IXA2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IXA2",
                "type": "external"
            }
        ],
        "mass": 41400.0,
        "length": 373,
        "protein_name": "Cellular communication network factor 1, like 2 precursor",
        "gene_name": "ccn1l2",
        "organism": "Zebrafish",
        "refseq_name": "cellular communication network factor 1, like 2 precursor",
        "refseq_ac": [
            {
                "id": "NP_001074456",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074456",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ccn1l2; cyr61-l2; cyr61l2; cyr61; zCyr61-c8; zgc:158158",
        "gene_names_refseq": "ccn1l2; cyr61-l2; cyr61l2; cyr61; zCyr61-c8; zgc:158158",
        "protein_names_uniprotkb": "Cellular communication network factor 1, like 2 precursor",
        "protein_names_refseq": "cellular communication network factor 1, like 2 precursor; cysteine-rich, angiogenic inducer, 61 like 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:553273)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "15725073;20503371;24051129;26930480;27130971;27428308;30348863;31429823;37122014;39397390",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.1175148.1, SRR26395013.67090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505379 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On or before Jan 5, 2017 this sequence version replaced XP_017212820.1, NP_001074456.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "secondary_ac_list": "A0A8M1NBV7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0030335 positive regulation of cell migration;GO:0045597 positive regulation of cell differentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IXA2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IXA9-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IXA9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IXA9",
                "type": "external"
            }
        ],
        "mass": 51374.0,
        "length": 468,
        "protein_name": "Adenylyl cyclase-associated protein",
        "gene_name": "cap2",
        "organism": "Zebrafish",
        "refseq_name": "adenylyl cyclase-associated protein 2",
        "refseq_ac": [
            {
                "id": "NP_957130",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957130",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cap2; zgc:113089; zgc:73317",
        "gene_names_refseq": "cap2; zgc:113089; zgc:73317",
        "protein_names_uniprotkb": "Adenylyl cyclase-associated protein",
        "protein_names_refseq": "CAP, adenylate cyclase-associated protein, 2; adenylyl cyclase-associated protein 2",
        "tax_id": 7955,
        "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930)",
        "pathway": " (dre:393809)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23022774;27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC091655.1, SRR32588720.972379.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC091655.1 and JBMGRA010000019.1. On or before May 27, 2016 this sequence version replaced XP_005159849.1, NP_957130.1., [RefSeq]; CAP2 plays an important role in enhancing cell motility, which may promote a more invasive behavior in the progression of hepatocellular carcinoma., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M6Z2X3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding;GO:0008179 adenylate cyclase binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007015 actin filament organization;GO:0000902 cell morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A0R4IXA9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IXC8",
                "type": "external"
            }
        ],
        "mass": 50090.0,
        "length": 447,
        "protein_name": "Tubulin beta chain",
        "gene_name": "tubb6",
        "organism": "Zebrafish",
        "refseq_name": "tubulin, beta 6 class V isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001017762",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017762",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tubb6; si:ch211-9a18.2; zgc:112515",
        "gene_names_refseq": "si:ch211-9a18.2; tubb6; zgc:112515",
        "protein_names_uniprotkb": "Tubulin beta chain",
        "protein_names_refseq": "tubulin, beta 6 class V isoform 1",
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        "pathway": " (dre:550458);  (R-DRE-2467813);  (R-DRE-2500257)",
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        "publication_id_list": "24947308;27189481;33316259",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01040434.1, GDQQ01016458.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476737, SAMEA4476754 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On or before Jun 16, 2016 this sequence version replaced XP_005162994.1, NP_001017762.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N5M5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule",
        "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0000226 microtubule cytoskeleton organization;GO:0007017 microtubule-based process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IXC8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IXF0-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IXF0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IXF0",
                "type": "external"
            }
        ],
        "mass": 22111.0,
        "length": 192,
        "protein_name": "FAS-associated death domain protein",
        "gene_name": "fadd",
        "organism": "Zebrafish",
        "refseq_name": "FAS-associated death domain protein",
        "refseq_ac": [
            {
                "id": "NP_001373289",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373289",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fadd",
        "gene_names_refseq": "fadd",
        "protein_names_uniprotkb": "FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associated death domain protein",
        "protein_names_refseq": "FAS-associated death domain protein",
        "tax_id": 7955,
        "disease": "immunodeficiency 90 (Disease Ontology:DOID:0061060); Alzheimer's disease (Disease Ontology:DOID:10652); leukemia (Disease Ontology:DOID:1240); acute myeloid leukemia (Disease Ontology:DOID:9119)",
        "pathway": " (dre:562317);  (R-DRE-3371378);  (R-DRE-5218900);  (R-DRE-5357786);  (R-DRE-5357905);  (R-DRE-5675482);  (R-DRE-69416);  (R-DRE-75158)",
        "pathway_count": 8,
        "publication_count": 10,
        "publication_id_list": "16888647;17656375;20573960;22357656;24627485;27471679;27834691;31492028;33535128;38892496",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC114285.1, EE111276.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 21, 2020 this sequence version replaced XP_001923893.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling., [UniProtKB, UniProtKB]; Establish that pax2 in combination with vax2 directly regulate the fas-associated death domain (fadd) gene, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1QLU8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0089720 caspase binding;GO:0005123 death receptor binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0031265 CD95 death-inducing signaling complex",
        "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0045087 innate immune response;GO:0001819 positive regulation of cytokine production;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0097191 extrinsic apoptotic signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A0R4IXF0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IY00_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IY00",
                "type": "external"
            }
        ],
        "mass": 38817.0,
        "length": 345,
        "protein_name": "Large ribosomal subunit protein uL3m",
        "gene_name": "mrpl3",
        "organism": "Zebrafish",
        "refseq_name": "large ribosomal subunit protein uL3m",
        "refseq_ac": [
            {
                "id": "NP_956301",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956301",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mrpl3; fj61d01; wu:fj61d01; zgc:66423",
        "gene_names_refseq": "fj61d01; mrpl3; wu:fj61d01; zgc:66423",
        "protein_names_uniprotkb": "Large ribosomal subunit protein uL3m; 39S ribosomal protein L3, mitochondrial",
        "protein_names_refseq": "large ribosomal subunit protein uL3m",
        "tax_id": 7955,
        "disease": "combined oxidative phosphorylation deficiency 9 (Disease Ontology:DOID:0111472)",
        "pathway": " (R-DRE-5389840);  (R-DRE-5419276);  (R-DRE-9937383)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01008173.1, GFIL01026852.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On or before Jul 21, 2025 this sequence version replaced XP_005159568.1, NP_956301.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B6E9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003735 structural constituent of ribosome",
        "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0006412 translation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IY00-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IY33-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IY33_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IY33",
                "type": "external"
            }
        ],
        "mass": 50562.0,
        "length": 454,
        "protein_name": "Target of Myb1 membrane trafficking protein isoform 1",
        "gene_name": "tom1",
        "organism": "Zebrafish",
        "refseq_name": "target of Myb1 membrane trafficking protein isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001338580",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338580",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tom1; Tom1l2",
        "gene_names_refseq": "Tom1l2; tom1",
        "protein_names_uniprotkb": "Target of Myb1 membrane trafficking protein isoform 1",
        "protein_names_refseq": "target of Myb1 membrane trafficking protein isoform 1",
        "tax_id": 7955,
        "disease": "immunodeficiency 85 (Disease Ontology:DOID:0061055)",
        "pathway": " (dre:553244);  (R-DRE-6798695)",
        "pathway_count": 2,
        "publication_count": 3,
        "publication_id_list": "18971206;27189481;27462902",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC139585.1, GFIL01041658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH551587.1, EH589099.1, BC078346.1 and JBMGRA010000003.1. On May 18, 2017 this sequence version replaced XP_688045.6. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]",
        "predicted_glycosites": 1,
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        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P9P8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030276 clathrin binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding",
        "go_cellular_component": "GO:0005768 endosome;GO:0016020 membrane",
        "go_biological_process": "GO:0007165 signal transduction;GO:0015031 protein transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4IY33-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4IY52-1",
        "uniprot_id": [
            {
                "id": "A0A0R4IY52_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IY52",
                "type": "external"
            }
        ],
        "mass": 82850.0,
        "length": 724,
        "protein_name": "Vacuolar protein sorting-associated protein 52 homolog",
        "gene_name": "vps52",
        "organism": "Zebrafish",
        "refseq_name": "vacuolar protein sorting-associated protein 52 homolog isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068071368",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071368",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "vps52",
        "gene_names_refseq": "vps52",
        "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 52 homolog",
        "protein_names_refseq": "vacuolar protein sorting-associated protein 52 homolog isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:556724)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M3AK60",
        "ec_number_list": [],
        "go_molecular_function": "GO:0019905 syntaxin binding",
        "go_cellular_component": "GO:0000938 GARP complex;GO:0005829 cytosol;GO:0005794 Golgi apparatus",
        "go_biological_process": "GO:0015031 protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0032456 endocytic recycling;GO:0007041 lysosomal transport;GO:0006896 Golgi to vacuole transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A0R4IY52-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4IY94_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4IY94",
                "type": "external"
            }
        ],
        "mass": 30583.0,
        "length": 279,
        "protein_name": "Retbindin isoform X1",
        "gene_name": "rtbdn",
        "organism": "Zebrafish",
        "refseq_name": "retbindin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009297376",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297376",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rtbdn; zgc:109949",
        "gene_names_refseq": "rtbdn; zgc:109949",
        "protein_names_uniprotkb": "Retbindin isoform X1",
        "protein_names_refseq": "retbindin isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:553764)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "25436775;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016324 apical plasma membrane",
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IZC9",
                "type": "external"
            }
        ],
        "mass": 56694.0,
        "length": 496,
        "protein_name": "Lysophospholipid acyltransferase 1",
        "gene_name": "mboat1",
        "organism": "Zebrafish",
        "refseq_name": "lysophospholipid acyltransferase 1",
        "refseq_ac": [
            {
                "id": "NP_001007397",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007397",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mboat1; fc11c04; wu:fc11c04; wu:fq24h09; zgc:101798",
        "gene_names_refseq": "fc11c04; mboat1; wu:fc11c04; wu:fq24h09; zgc:101798",
        "protein_names_uniprotkb": "Lysophospholipid acyltransferase 1",
        "protein_names_refseq": "lysophospholipid acyltransferase 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:572841);  (R-DRE-1482801);  (R-DRE-1482839)",
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        "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL935025.11. On or before Sep 2, 2007 this sequence version replaced XP_707374.2, NP_001007397.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "go_molecular_function": "GO:0016746 acyltransferase activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0030258 lipid modification",
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                "url": "https://www.uniprot.org/uniprot/A0A0R4IZE7",
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        ],
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        "length": 330,
        "protein_name": "PAK4-inhibitor INKA2",
        "gene_name": "inka2",
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        "refseq_name": "PAK4-inhibitor INKA2 isoform X1",
        "refseq_ac": [
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                "id": "XP_005167187",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167187",
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        "protein_names_refseq": "PAK4-inhibitor INKA2 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "AT-rich interactive domain-containing protein 3",
        "gene_name": "arid3b",
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        "refseq_name": "AT-rich interactive domain-containing protein 3B",
        "refseq_ac": [
            {
                "id": "NP_001076471",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076471",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "arid3b; wu:fc16g09; wu:fc87c02; zgc:158235",
        "gene_names_refseq": "arid3b; wu:fc16g09; wu:fc87c02; zgc:158235",
        "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 3; ARID domain-containing protein",
        "protein_names_refseq": "AT rich interactive domain 3B (BRIGHT-like); AT rich interactive domain 3B (Bright like); AT-rich interactive domain-containing protein 3B",
        "tax_id": 7955,
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        "pathway": " (dre:571249)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019717.1, BC131867.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Jun 15, 2024 this sequence version replaced XP_005163185.1, NP_001076471.1., [RefSeq]; Transcription factor., [UniProtKB, UniProtKB, UniProtKB]",
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        ],
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        "protein_name": "Uncharacterized protein LOC541437",
        "gene_name": "ptbp2a",
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            {
                "id": "NP_001315358",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315358",
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        ],
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        "gene_names_refseq": "ptbp2a; zgc:113074",
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        "protein_names_refseq": "uncharacterized protein LOC541437",
        "tax_id": 7955,
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        "gene_name": "si:dkey-34d22.1",
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        "refseq_name": "discoidin, CUB and LCCL domain-containing protein 1 isoform X1",
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        ],
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158202",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "fam189b",
        "gene_names_refseq": "fam189b",
        "protein_names_uniprotkb": "Protein ENTREP3 isoform X1",
        "protein_names_refseq": "protein ENTREP3 isoform X1",
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        "go_cellular_component": "GO:0016020 membrane",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A0R4J720_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4J720",
                "type": "external"
            }
        ],
        "mass": 60655.0,
        "length": 551,
        "protein_name": "Major facilitator superfamily domain-containing protein 2B",
        "gene_name": "mfsd2b",
        "organism": "Zebrafish",
        "refseq_name": "major facilitator superfamily domain-containing protein 2B",
        "refseq_ac": [
            {
                "id": "NP_001352893",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352893",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mfsd2b; si:dkeyp-115a10.3; si:dkeyp-115a10.4",
        "gene_names_refseq": "mfsd2b; si:dkeyp-115a10.3; si:dkeyp-115a10.4",
        "protein_names_uniprotkb": "Major facilitator superfamily domain-containing protein 2B",
        "protein_names_refseq": "major facilitator superfamily domain containing 2B; major facilitator superfamily domain-containing protein 2B",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:566968);  (R-DRE-1660661)",
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        "publication_id_list": "26469318;27189481;28878041",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01037803.1, SRR32588730.16080281.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Sep 19, 2018 this sequence version replaced XP_695343.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8N7T7R2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0015293 symporter activity;GO:0046624 sphingolipid transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0051977 lysophospholipid transport;GO:0006869 lipid transport;GO:0055085 transmembrane transport;GO:0008643 carbohydrate transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0A0R4J720-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A0R4J8N1-1",
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            {
                "id": "A0A0R4J8N1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A0R4J8N1",
                "type": "external"
            }
        ],
        "mass": 59236.0,
        "length": 539,
        "protein_name": "CAP-Gly domain-containing linker protein 3 isoform X1",
        "gene_name": "clip3",
        "organism": "Zebrafish",
        "refseq_name": "CAP-Gly domain-containing linker protein 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005157797",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157797",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "clip3",
        "gene_names_refseq": "clip3",
        "protein_names_uniprotkb": "CAP-Gly domain-containing linker protein 3 isoform X1",
        "protein_names_refseq": "CAP-Gly domain-containing linker protein 3 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:562450);  (R-DRE-5357905)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "go_molecular_function": "GO:0051010 microtubule plus-end binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005938 cell cortex;GO:0035371 microtubule plus-end",
        "go_biological_process": "GO:0031122 cytoplasmic microtubule organization",
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        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A140LFZ1-1",
        "uniprot_id": [
            {
                "id": "A0A140LFZ1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A140LFZ1",
                "type": "external"
            }
        ],
        "mass": 21001.0,
        "length": 205,
        "protein_name": "Histone H1",
        "gene_name": "si:ch73-368j24.11",
        "organism": "Zebrafish",
        "refseq_name": "histone H1-like",
        "refseq_ac": [
            {
                "id": "XP_005168858",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168858",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-368j24.11",
        "gene_names_refseq": "si:ch73-368j24.11",
        "protein_names_uniprotkb": "Histone H1",
        "protein_names_refseq": "histone H1-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:562307);  (R-DRE-140342)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0A8M2BG38",
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        "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome",
        "go_biological_process": "GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A140LG01-1",
        "uniprot_id": [
            {
                "id": "A0A140LG01_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A140LG01",
                "type": "external"
            }
        ],
        "mass": 43261.0,
        "length": 381,
        "protein_name": "MYG1 exonuclease",
        "gene_name": "myg1",
        "organism": "Zebrafish",
        "refseq_name": "MYG1 exonuclease",
        "refseq_ac": [
            {
                "id": "NP_001296417",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296417",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "myg1; fa14e09; im:6894200; wu:fa14e09; zgc:136866",
        "gene_names_refseq": "fa14e09; im:6894200; myg1; wu:fa14e09; zgc:136866",
        "protein_names_uniprotkb": "MYG1 exonuclease",
        "protein_names_refseq": "MYG1 exonuclease; melanocyte proliferating gene 1",
        "tax_id": 7955,
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        "pathway": " (dre:664752)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01021151.1, SRR26395014.1053490.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 6, 2015 this sequence version replaced XP_009303985.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M1P777",
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        "record_id": "A0A140LG01-1",
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        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A140LG17_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A140LG17",
                "type": "external"
            }
        ],
        "mass": 23049.0,
        "length": 207,
        "protein_name": "TSC22 domain family protein 3",
        "gene_name": "tsc22d3",
        "organism": "Zebrafish",
        "refseq_name": "TSC22 domain family protein 3 isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001335409",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335409",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tsc22d3; zgc:64189; zgc:65831; zgc:77028",
        "gene_names_refseq": "si:ch211-220e11.3; tsc22d3; zgc:64189; zgc:65831; zgc:77028",
        "protein_names_uniprotkb": "TSC22 domain family protein 3",
        "protein_names_refseq": "TSC22 domain family protein 3 isoform 2; gilz",
        "tax_id": 7955,
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        "pathway": " (dre:393541)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "17848559;19874812;20339547;21887364;23665588;30981015;31249786;31812088;31829580;32030813",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01042100.1, DN899493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505389, SAMEA4476760 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Zebrafish tsc22d3 is a ventralizing gene and plays a role in early embryogenesis, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P9N7",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A140LG17-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A140LG54-1",
        "uniprot_id": [
            {
                "id": "A0A140LG54_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A140LG54",
                "type": "external"
            }
        ],
        "mass": 13594.0,
        "length": 124,
        "protein_name": "Histone H2B",
        "gene_name": "si:dkey-23a13.22",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC100536401",
        "refseq_ac": [
            {
                "id": "NP_001353363",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353363",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-23a13.22",
        "gene_names_refseq": "si:dkey-23a13.22",
        "protein_names_uniprotkb": "Histone H2B",
        "protein_names_refseq": "Histone H2B-like; uncharacterized protein LOC100536401",
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        "protein_name": "ABC-type glutathione-S-conjugate transporter",
        "gene_name": "abcc6b.2",
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        "protein_names_uniprotkb": "ABC-type glutathione-S-conjugate transporter; 7.6.2.3",
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        "disease": "arterial calcification of infancy (Disease Ontology:DOID:0050644); pseudoxanthoma elasticum (Disease Ontology:DOID:2738); coronary artery disease (Disease Ontology:DOID:3393)",
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane",
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        "protein_name": "Uncharacterized protein si:dkey-88n24.11",
        "gene_name": "si:dkey-88n24.11",
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        "refseq_ac": [
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        "gene_names_refseq": "si:dkey-88n24.11",
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        "protein_names_refseq": "uncharacterized protein si:dkey-88n24.11",
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        "predicted_glycosites": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Transcriptional repressor NF-X1",
        "gene_name": "nfx1",
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        "refseq_name": "transcriptional repressor NF-X1",
        "refseq_ac": [
            {
                "id": "XP_690559",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690559",
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        ],
        "gene_names_uniprotkb": "nfx1",
        "gene_names_refseq": "nfx1",
        "protein_names_uniprotkb": "Transcriptional repressor NF-X1; Nuclear transcription factor, X box-binding protein 1",
        "protein_names_refseq": "transcriptional repressor NF-X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690559.3. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016740 transferase activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription",
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    {
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        ],
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        "protein_name": "Growth arrest-specific protein 2",
        "gene_name": "gas2b",
        "organism": "Zebrafish",
        "refseq_name": "growth arrest-specific protein 2",
        "refseq_ac": [
            {
                "id": "XP_002662883",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662883",
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        "gene_names_uniprotkb": "gas2b",
        "gene_names_refseq": "gas2b",
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        "tax_id": 7955,
        "disease": "autosomal recessive nonsyndromic deafness 125 (Disease Ontology:DOID:0061124); sensorineural hearing loss (Disease Ontology:DOID:10003)",
        "pathway": " (dre:567205);  (R-DRE-264870)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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    },
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        ],
        "mass": 57038.0,
        "length": 517,
        "protein_name": "Adenosine deaminase domain-containing protein 2",
        "gene_name": "adad2",
        "organism": "Zebrafish",
        "refseq_name": "adenosine deaminase domain-containing protein 2",
        "refseq_ac": [
            {
                "id": "XP_687183",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687183",
                "type": "external"
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        "gene_names_refseq": "adad2",
        "protein_names_uniprotkb": "Adenosine deaminase domain-containing protein 2",
        "protein_names_refseq": "adenosine deaminase domain-containing protein 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:558824)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008251 tRNA-specific adenosine deaminase activity;GO:0003725 double-stranded RNA binding;GO:0003726 double-stranded RNA adenosine deaminase activity",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006396 RNA processing;GO:0006382 adenosine to inosine editing",
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A1D5NSL5",
                "type": "external"
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        ],
        "mass": 21888.0,
        "length": 193,
        "protein_name": "TRAF-interacting protein with FHA domain-containing protein A",
        "gene_name": "tifa",
        "organism": "Zebrafish",
        "refseq_name": "TRAF-interacting protein with FHA domain-containing protein A",
        "refseq_ac": [
            {
                "id": "NP_001373475",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373475",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tifa; si:ch211-15b10.6",
        "gene_names_refseq": "si:ch211-15b10.6; tifa",
        "protein_names_uniprotkb": "TRAF-interacting protein with FHA domain-containing protein A",
        "protein_names_refseq": "TRAF-interacting protein with FHA domain-containing protein A",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:560548)",
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        "publication_id_list": "26469318",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC086730.1, EH432683.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476810 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2025 this sequence version replaced NP_001373475.1., [RefSeq]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2BJQ1",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005737 cytoplasm",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A1D6UPT1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A1D6UPT1",
                "type": "external"
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        ],
        "mass": 72133.0,
        "length": 653,
        "protein_name": "Terminal nucleotidyltransferase 4A",
        "gene_name": "tent4b",
        "organism": "Zebrafish",
        "refseq_name": "terminal nucleotidyltransferase 4B",
        "refseq_ac": [
            {
                "id": "NP_001313625",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313625",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tent4b; papd5; polsl",
        "gene_names_refseq": "papd5; polsl; tent4b",
        "protein_names_uniprotkb": "Terminal nucleotidyltransferase 4A; 2.7.7.19; DNA polymerase sigma; Non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal guanylyltransferase",
        "protein_names_refseq": "PAP associated domain containing 5; TUTase3; polymerase (DNA directed) sigma like; terminal nucleotidyltransferase 4B",
        "tax_id": 7955,
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        "pathway": " (dre:568678)",
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        "publication_id_list": "15133664;20859253;26469318;27189481;29625039",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01002709.1, BC133101.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505376, SAMEA3505382 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 24, 2016 this sequence version replaced XP_697115.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P2W0",
        "ec_number_list": [
            {
                "id": "2.7.7.19",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19",
                "type": "external"
            },
            {
                "id": "2.7.7.52",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52",
                "type": "external"
            }
        ],
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        "gene_names_refseq": "nt5c1aa; nt5c1a; si:dkey-255n2.1",
        "protein_names_uniprotkb": "5'-nucleotidase, cytosolic IAa isoform X1",
        "protein_names_refseq": "5'-nucleotidase, cytosolic IAa isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-73621);  (R-DRE-74259)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B6Q0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0000166 nucleotide binding;GO:0008253 5'-nucleotidase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0009117 nucleotide metabolic process;GO:0046085 adenosine metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A286Y9C9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A286YA88-1",
        "uniprot_id": [
            {
                "id": "A0A286YA88_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A286YA88",
                "type": "external"
            }
        ],
        "mass": 13940.0,
        "length": 124,
        "protein_name": "Islet amyloid polypeptide",
        "gene_name": "iapp",
        "organism": "Zebrafish",
        "refseq_name": "islet amyloid polypeptide",
        "refseq_ac": [
            {
                "id": "XP_002661886",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661886",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "iapp",
        "gene_names_refseq": "iapp",
        "protein_names_uniprotkb": "Islet amyloid polypeptide",
        "protein_names_refseq": "islet amyloid polypeptide",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-419812)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002661886.2. COMPLETENESS: full length., [RefSeq]; Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RH74;A0AC58JF62",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005179 hormone activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A286YA88-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A286YA92-1",
        "uniprot_id": [
            {
                "id": "A0A286YA92_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A286YA92",
                "type": "external"
            }
        ],
        "mass": 49263.0,
        "length": 441,
        "protein_name": "Phakinin isoform X1",
        "gene_name": "bfsp2",
        "organism": "Zebrafish",
        "refseq_name": "phakinin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009296890",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296890",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bfsp2; zgc:103750",
        "gene_names_refseq": "bfsp2; zgc:103750",
        "protein_names_uniprotkb": "Phakinin isoform X1",
        "protein_names_refseq": "phakinin isoform X1",
        "tax_id": 7955,
        "disease": "cataract 12 multiple types (Disease Ontology:DOID:0110239); cataract (Disease Ontology:DOID:83)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3B0B9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005198 structural molecule activity",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005882 intermediate filament",
        "go_biological_process": "GO:0045109 intermediate filament organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A286YA92-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A286YAE5-1",
        "uniprot_id": [
            {
                "id": "A0A286YAE5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A286YAE5",
                "type": "external"
            }
        ],
        "mass": 84388.0,
        "length": 772,
        "protein_name": "CCR4-NOT transcription complex subunit 4",
        "gene_name": "cnot4a",
        "organism": "Zebrafish",
        "refseq_name": "CCR4-NOT transcription complex subunit 4",
        "refseq_ac": [
            {
                "id": "XP_697509",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697509",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cnot4a",
        "gene_names_refseq": "cnot4a",
        "protein_names_uniprotkb": "CCR4-NOT transcription complex subunit 4; 2.3.2.27; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp; RING-type E3 ubiquitin transferase CNOT4",
        "protein_names_refseq": "CCR4-NOT transcription complex subunit 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569055)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_697509.1. COMPLETENESS: full length., [RefSeq]; Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7URD1;A0AC58IY46",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030014 CCR4-NOT complex",
        "go_biological_process": "GO:0016567 protein ubiquitination",
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        "hit_score": 0.1,
        "record_id": "A0A286YAE5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A286YAJ7-1",
        "uniprot_id": [
            {
                "id": "A0A286YAJ7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A286YAJ7",
                "type": "external"
            }
        ],
        "mass": 54917.0,
        "length": 507,
        "protein_name": "Abl interactor 1b isoform X1",
        "gene_name": "abi1b",
        "organism": "Zebrafish",
        "refseq_name": "abl interactor 1b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005171233",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171233",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "abi1b; wu:fe48a10; zgc:153534",
        "gene_names_refseq": "abi1b; wu:fe48a10; zgc:153534",
        "protein_names_uniprotkb": "Abl interactor 1b isoform X1",
        "protein_names_refseq": "abl interactor 1b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:767738);  (R-DRE-2029482);  (R-DRE-5663213);  (R-DRE-9013149);  (R-DRE-9013404);  (R-DRE-9013423)",
        "pathway_count": 6,
        "publication_count": 5,
        "publication_id_list": "19439512;26039894;26469318;27189481;28252024",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2BIW1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0035591 signaling adaptor activity",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0030027 lamellipodium;GO:0030175 filopodium;GO:0031209 SCAR complex;GO:0098858 actin-based cell projection",
        "go_biological_process": "GO:0001764 neuron migration;GO:0048858 cell projection morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0A286YAJ7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A286YAW6-1",
        "uniprot_id": [
            {
                "id": "A0A286YAW6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A286YAW6",
                "type": "external"
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        ],
        "mass": 55283.0,
        "length": 498,
        "protein_name": "Thyrotropin-releasing hormone receptor",
        "gene_name": "trhr2",
        "organism": "Zebrafish",
        "refseq_name": "thyrotropin releasing hormone receptor 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005159153",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159153",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "trhr2; si:ch211-187i23.1",
        "gene_names_refseq": "si:ch211-187i23.1; trhr2",
        "protein_names_uniprotkb": "Thyrotropin-releasing hormone receptor; Thyroliberin receptor",
        "protein_names_refseq": "thyrotropin releasing hormone receptor 2 isoform X1",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "gene_name": "wdr59",
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        "protein_names_refseq": "GATOR2 complex protein WDR59 isoform X1",
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        "pathway": " (dre:103909113);  (R-DRE-9639288)",
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        "predicted_glycosites": 2,
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                "url": "https://www.uniprot.org/uniprot/A0A286YBI9",
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        "length": 1473,
        "protein_name": "C-type mannose receptor 2",
        "gene_name": "mrc2",
        "organism": "Zebrafish",
        "refseq_name": "C-type mannose receptor 2",
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            {
                "id": "XP_001344010",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344010",
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        "gene_names_uniprotkb": "mrc2",
        "gene_names_refseq": "mrc2",
        "protein_names_uniprotkb": "C-type mannose receptor 2",
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        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001344010.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
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        "protein_name": "Unconventional myosin-Ig isoform X1",
        "gene_name": "myo1g",
        "organism": "Zebrafish",
        "refseq_name": "unconventional myosin-Ig isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005170126",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170126",
                "type": "external"
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        "gene_names_uniprotkb": "myo1g; si:dkeyp-92c9.3",
        "gene_names_refseq": "myo1g; si:dkeyp-92c9.3",
        "protein_names_uniprotkb": "Unconventional myosin-Ig isoform X1",
        "protein_names_refseq": "unconventional myosin-Ig isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:571487)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_biological_process": "GO:0048731 system development;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0007032 endosome organization;GO:0030048 actin filament-based movement",
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                "url": "https://www.uniprot.org/uniprot/A0A2R8PV77",
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        ],
        "mass": 40184.0,
        "length": 355,
        "protein_name": "Hydroxylysine kinase",
        "gene_name": "hykk.1",
        "organism": "Zebrafish",
        "refseq_name": "hydroxylysine kinase-like",
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            {
                "id": "XP_688090",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688090",
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        ],
        "gene_names_uniprotkb": "hykk.1",
        "gene_names_refseq": "hykk.1",
        "protein_names_uniprotkb": "Hydroxylysine kinase; 2.7.1.81",
        "protein_names_refseq": "hydroxylysine kinase-like",
        "tax_id": 7955,
        "disease": "chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_688090.2. COMPLETENESS: full length., [RefSeq]; Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine., [UniProtKB, UniProtKB]",
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                "id": "2.7.1.81",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.81",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0047992 hydroxylysine kinase activity;GO:0019202 amino acid kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
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        "kg_view_protein": true
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    {
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            {
                "id": "A0A2R8PX08_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8PX08",
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        ],
        "mass": 177951.0,
        "length": 1610,
        "protein_name": "Adhesion G protein-coupled receptor B1 isoform X1",
        "gene_name": "adgrb1a",
        "organism": "Zebrafish",
        "refseq_name": "adhesion G protein-coupled receptor B1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290826",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290826",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "adgrb1a",
        "gene_names_refseq": "adgrb1a",
        "protein_names_uniprotkb": "Adhesion G protein-coupled receptor B1 isoform X1",
        "protein_names_refseq": "adhesion G protein-coupled receptor B1 isoform X1",
        "tax_id": 7955,
        "disease": "stomach cancer (Disease Ontology:DOID:10534); invasive ductal carcinoma (Disease Ontology:DOID:3008); glioblastoma (Disease Ontology:DOID:3068); malignant astrocytoma (Disease Ontology:DOID:3069); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); renal cell carcinoma (Disease Ontology:DOID:4450); colorectal cancer (Disease Ontology:DOID:9256)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibits angiogenesis in a CD36-dependent manner., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8M3AJD7",
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
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        "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0016525 negative regulation of angiogenesis;GO:0007186 G protein-coupled receptor signaling pathway;GO:0043652 engulfment of apoptotic cell;GO:0007399 nervous system development",
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        "protein_name": "NAD(P)H dehydrogenase [quinone] 1",
        "gene_name": "nqo1",
        "organism": "Zebrafish",
        "refseq_name": "NAD(P)H dehydrogenase [quinone] 1 isoform 1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191201",
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        "gene_names_refseq": "nqo1; wu:fb63c10; zgc:77191",
        "protein_names_uniprotkb": "NAD(P)H dehydrogenase [quinone] 1; 1.6.5.2; Azoreductase; DT-diaphorase; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1",
        "protein_names_refseq": "NAD(P)H dehydrogenase [quinone] 1 isoform 1",
        "tax_id": 7955,
        "disease": "small cell carcinoma (Disease Ontology:DOID:0050685); hypertension (Disease Ontology:DOID:10763); alcoholic hepatitis (Disease Ontology:DOID:12351); leukemia (Disease Ontology:DOID:1240); breast cancer (Disease Ontology:DOID:1612); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); lung non-small cell carcinoma (Disease Ontology:DOID:3908); urinary system cancer (Disease Ontology:DOID:3996); macular degeneration (Disease Ontology:DOID:4448); lung disease (Disease Ontology:DOID:850); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538); pulmonary emphysema (Disease Ontology:DOID:9675); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
        "pathway": " (dre:322506);  (R-DRE-211945);  (R-DRE-350562)",
        "pathway_count": 3,
        "publication_count": 10,
        "publication_id_list": "16109975;18258299;18618001;19420631;21392494;37047777;37071853;37337786;37748761;37951024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH498485.1, SRR32588732.17878604.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 16,
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        "secondary_ac_list": "A0A8M1NYZ9",
        "ec_number_list": [
            {
                "id": "1.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003955 NAD(P)H dehydrogenase (quinone) activity;GO:0050136 NADH dehydrogenase (quinone) (non-electrogenic) activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0006979 response to oxidative stress;GO:0071466 cellular response to xenobiotic stimulus;GO:0042373 vitamin K metabolic process",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A2R8PWA9",
                "type": "external"
            }
        ],
        "mass": 218448.0,
        "length": 1936,
        "protein_name": "Myotubularin-related protein 5 isoform X1",
        "gene_name": "sbf1",
        "organism": "Zebrafish",
        "refseq_name": "myotubularin-related protein 5 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009298445",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009298445",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sbf1; wu:fj45d12; zgc:92634",
        "gene_names_refseq": "sbf1; wu:fj45d12; zgc:92634",
        "protein_names_uniprotkb": "Myotubularin-related protein 5 isoform X1",
        "protein_names_refseq": "myotubularin-related protein 5 isoform X1",
        "tax_id": 7955,
        "disease": "Charcot-Marie-Tooth disease type 4B3 (Disease Ontology:DOID:0110194)",
        "pathway": " (dre:568277);  (R-DRE-1483248);  (R-DRE-8876198)",
        "pathway_count": 3,
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        "publication_id_list": "15520368;27189481;28252024",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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        "secondary_ac_list": "A0A8M3AYP0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane",
        "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0048932 myelination of posterior lateral line nerve axons",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8PYF0-1",
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            {
                "id": "A0A2R8PYF0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8PYF0",
                "type": "external"
            }
        ],
        "mass": 223242.0,
        "length": 2000,
        "protein_name": "Stereocilin",
        "gene_name": "strc1",
        "organism": "Zebrafish",
        "refseq_name": "stereocilin",
        "refseq_ac": [
            {
                "id": "XP_005169000",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169000",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "strc1",
        "gene_names_refseq": "strc1",
        "protein_names_uniprotkb": "Stereocilin",
        "protein_names_refseq": "stereocilin",
        "tax_id": 7955,
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        "pathway": " (dre:101886410)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_005169000.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2BGU4",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0009986 cell surface",
        "go_biological_process": "GO:0007160 cell-matrix adhesion",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8PYF0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8PZ71-1",
        "uniprot_id": [
            {
                "id": "A0A2R8PZ71_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8PZ71",
                "type": "external"
            }
        ],
        "mass": 42682.0,
        "length": 383,
        "protein_name": "Trophoblast glycoprotein-like precursor",
        "gene_name": "tpbg1a",
        "organism": "Zebrafish",
        "refseq_name": "trophoblast glycoprotein-like precursor",
        "refseq_ac": [
            {
                "id": "NP_001239390",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239390",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tpbg1a; 5T4; Waif1b; tpbgl",
        "gene_names_refseq": "5T4; Waif1b; tpbg1a; tpbgl",
        "protein_names_uniprotkb": "Trophoblast glycoprotein-like precursor",
        "protein_names_refseq": "Wnt-activated inhibitory factor 1b; trophoblast glycoprotein-like precursor; trophoblast glycoprotein-like",
        "tax_id": 7955,
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        "pathway": " (dre:100537897)",
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        "publication_id_list": "22100263",
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        "function": "##Evidence-Data-START## Transcript exon combination :: JN653074.1, SRR32588717.8154035.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Dec 16, 2016 this sequence version replaced NP_001239390.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1NYX4",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway",
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        "hit_score": 0.2,
        "record_id": "A0A2R8PZ71-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q094-1",
        "uniprot_id": [
            {
                "id": "A0A2R8Q094_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q094",
                "type": "external"
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        ],
        "mass": 80819.0,
        "length": 724,
        "protein_name": "Spindle and centriole-associated protein 1",
        "gene_name": "spice1",
        "organism": "Zebrafish",
        "refseq_name": "spindle and centriole-associated protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005162750",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162750",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "spice1; ccdc52; zgc:101558",
        "gene_names_refseq": "ccdc52; spice1; zgc:101558",
        "protein_names_uniprotkb": "Spindle and centriole-associated protein 1; Coiled-coil domain-containing protein 52",
        "protein_names_refseq": "spindle and centriole-associated protein 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005814 centriole",
        "go_biological_process": "GO:0051310 metaphase chromosome alignment;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0046599 regulation of centriole replication",
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        "kg_view_protein": true
    },
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0A2R8Q213",
                "type": "external"
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        ],
        "mass": 89878.0,
        "length": 797,
        "protein_name": "Methyl-CpG-binding domain protein 1a",
        "gene_name": "mbd1a",
        "organism": "Zebrafish",
        "refseq_name": "methyl-CpG-binding domain protein 1a",
        "refseq_ac": [
            {
                "id": "NP_001296818",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296818",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mbd1a; fc39d12; fc83c09; im:7136442; si:dkey-242k1.6; wu:fc39d12; wu:fc83c09",
        "gene_names_refseq": "fc39d12; fc83c09; im:7136442; mbd1a; si:dkey-242k1.6; wu:fc39d12; wu:fc83c09",
        "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 1a",
        "protein_names_refseq": "methyl-CpG-binding domain protein 1a",
        "tax_id": 7955,
        "disease": "lung cancer (Disease Ontology:DOID:1324)",
        "pathway": " (dre:797143)",
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        "publication_id_list": "26469318;27189481",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395013.456543.1, SRR32588732.1122569.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P7D0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008327 methyl-CpG binding;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q2I0-1",
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            {
                "id": "A0A2R8Q2I0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q2I0",
                "type": "external"
            }
        ],
        "mass": 84724.0,
        "length": 770,
        "protein_name": "Neuronal PAS domain-containing protein 1",
        "gene_name": "npas1",
        "organism": "Zebrafish",
        "refseq_name": "neuronal PAS domain-containing protein 1",
        "refseq_ac": [
            {
                "id": "NP_001315312",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315312",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "npas1; npas3b; si:dkeyp-13e2.1",
        "gene_names_refseq": "npas1; npas3b; si:dkeyp-13e2.1",
        "protein_names_uniprotkb": "Neuronal PAS domain-containing protein 1",
        "protein_names_refseq": "neuronal PAS domain protein 3b; neuronal PAS domain-containing protein 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:559419)",
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        "publication_id_list": "19449054;25556858;26469318;27189481;35524578",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01028452.1, SRR32588718.19010158.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 14, 2016 this sequence version replaced XP_687851.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048513 animal organ development",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8Q2S1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q2S1",
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        ],
        "mass": 27353.0,
        "length": 239,
        "protein_name": "OCIA domain-containing protein 1",
        "gene_name": "LOC553528",
        "organism": "Zebrafish",
        "refseq_name": "OCIA domain-containing protein 1-like isoform a",
        "refseq_ac": [
            {
                "id": "NP_001314996",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314996",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC553528",
        "gene_names_refseq": "LOC553528",
        "protein_names_uniprotkb": "OCIA domain-containing protein 1",
        "protein_names_refseq": "OCIA domain-containing protein 1-like isoform a",
        "tax_id": 7955,
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        "pathway": " (dre:553528)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01022692.1, GDQH01020610.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 25, 2025 this sequence version replaced NP_001314996.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005768 endosome",
        "go_biological_process": "GO:2000736 regulation of stem cell differentiation",
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A2R8QST4",
                "type": "external"
            }
        ],
        "mass": 143824.0,
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        "protein_name": "ubiquitinyl hydrolase 1",
        "gene_name": "usp31",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin carboxyl-terminal hydrolase 31 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005164285",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164285",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "usp31",
        "gene_names_refseq": "usp31",
        "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12",
        "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 31 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:564487)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0016787 hydrolase activity",
        "go_cellular_component": "GO:0005634 nucleus",
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    {
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        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0A2R8Q307",
                "type": "external"
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        ],
        "mass": 66154.0,
        "length": 596,
        "protein_name": "Forkhead box protein J3",
        "gene_name": "foxj3",
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        "refseq_name": "forkhead box protein J3",
        "refseq_ac": [
            {
                "id": "NP_001313317",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313317",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "foxj3; wu:fd99b01",
        "gene_names_refseq": "foxj3; wu:fd99b01",
        "protein_names_uniprotkb": "Forkhead box protein J3",
        "protein_names_refseq": "forkhead box protein J3",
        "tax_id": 7955,
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        "pathway": " (dre:797147)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588731.3213269.1, SRR26395012.366463.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 17, 2016 this sequence version replaced XP_009304339.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q356-1",
        "uniprot_id": [
            {
                "id": "A0A2R8Q356_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q356",
                "type": "external"
            }
        ],
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        "length": 389,
        "protein_name": "CXADR-like membrane protein",
        "gene_name": "clmpa",
        "organism": "Zebrafish",
        "refseq_name": "CXADR-like membrane protein",
        "refseq_ac": [
            {
                "id": "XP_695564",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695564",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "clmpa",
        "gene_names_refseq": "clmpa",
        "protein_names_uniprotkb": "CXADR-like membrane protein",
        "protein_names_refseq": "CXADR-like membrane protein",
        "tax_id": 7955,
        "disease": "short bowel syndrome (Disease Ontology:DOID:10605)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_695564.3. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8N7UR95",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane;GO:0005881 cytoplasmic microtubule",
        "go_biological_process": "GO:0048565 digestive tract development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8Q356-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q3N8-1",
        "uniprot_id": [
            {
                "id": "A0A2R8Q3N8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q3N8",
                "type": "external"
            }
        ],
        "mass": 63765.0,
        "length": 574,
        "protein_name": "sphinganine-1-phosphate aldolase",
        "gene_name": "sgpl1",
        "organism": "Zebrafish",
        "refseq_name": "sphingosine-1-phosphate lyase 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005156777",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156777",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sgpl1; zgc:162153",
        "gene_names_refseq": "sgpl1; zgc:162153",
        "protein_names_uniprotkb": "sphinganine-1-phosphate aldolase; 4.1.2.27; Sphingosine-1-phosphate aldolase",
        "protein_names_refseq": "sphingosine-1-phosphate lyase 1 isoform X1",
        "tax_id": 7955,
        "disease": "RENI syndrome (Disease Ontology:DOID:0080265)",
        "pathway": " (R-DRE-9845614)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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            {
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        ],
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            {
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        "gene_names_uniprotkb": "tmtopsb; si:ch211-174k6.1; tmt3b; tmtops1b",
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        "protein_names_uniprotkb": "Teleost multiple tissue opsin b",
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        "pathway": " (dre:100334480)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "refseq_ac": [
            {
                "id": "NP_001076531",
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        "protein_name": "T-box transcription factor TBX22 isoform X1",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157203",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_biological_process": "GO:0001708 cell fate specification;GO:0060429 epithelium development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription",
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            {
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        "protein_names_uniprotkb": "BAF chromatin remodeling complex subunit BCL11B a isoform 1",
        "protein_names_refseq": "B cell CLL/lymphoma 11Ba; B-cell CLL/lymphoma 11Ba (zinc finger protein); BAF chromatin remodeling complex subunit BCL11B a isoform 1; BAF chromatin remodeling complex subunit BCL11B a; BCL11B, BAF complex component a",
        "tax_id": 7955,
        "disease": "immunodeficiency 49 (Disease Ontology:DOID:0111979)",
        "pathway": " (dre:100093707)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01025326.1, SRR32588727.1082691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 14, 2016 this sequence version replaced XP_005158714.1. Sequence Note:. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
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        "protein_name": "Testican-2",
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            {
                "id": "XP_005156999",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156999",
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        "protein_names_uniprotkb": "Testican-2; SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2",
        "protein_names_refseq": "testican-2",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May participate in diverse steps of neurogenesis. Binds calcium., [UniProtKB, UniProtKB]",
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A2R8Q8Y9",
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        ],
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        "protein_name": "Septin 9b isoform a",
        "gene_name": "septin9b",
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        "refseq_name": "septin 9b isoform a",
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            {
                "id": "NP_001314903",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314903",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "septin9b; sept9b; zgc:113041",
        "gene_names_refseq": "sept9b; septin9b; zgc:113041",
        "protein_names_uniprotkb": "Septin 9b isoform a",
        "protein_names_refseq": "septin 9b isoform a",
        "tax_id": 7955,
        "disease": "brachial plexus neuritis (Disease Ontology:DOID:3689); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:541494)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01034833.1, SRR32588724.102891.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 1, 2016 this sequence version replaced XP_005166238.1. Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Zebrafish possess two genes, sept9a and sept9b that, like humans, express multiple transcripts. Publication Status: Online-Only, [RefSeq, PubMed]",
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        "go_biological_process": "GO:0008104 intracellular protein localization;GO:0061640 cytoskeleton-dependent cytokinesis;GO:0051301 cell division",
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    {
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        ],
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        "protein_name": "DNA replication complex GINS protein SLD5",
        "gene_name": "gins4",
        "organism": "Zebrafish",
        "refseq_name": "DNA replication complex GINS protein SLD5",
        "refseq_ac": [
            {
                "id": "NP_001003546",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003546",
                "type": "external"
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        ],
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        "gene_names_refseq": "gins4; im:7137690; zgc:100817",
        "protein_names_uniprotkb": "DNA replication complex GINS protein SLD5",
        "protein_names_refseq": "DNA replication complex GINS protein SLD5",
        "tax_id": 7955,
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        "pathway": " (dre:572562);  (R-DRE-176974)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EE697537.1, BC078242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EE697537.1, EH534241.1 and EH566551.1. On Dec 10, 2008 this sequence version replaced NP_001003546.1., [RefSeq]; Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8M1N188",
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        "go_cellular_component": "GO:0000811 GINS complex",
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        "hit_score": 0.3,
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        "kg_view_protein": true
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A2R8Q9M5",
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            }
        ],
        "mass": 117530.0,
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        "protein_name": "Toll-like receptor 8b precursor",
        "gene_name": "tlr8b",
        "organism": "Zebrafish",
        "refseq_name": "toll-like receptor 8b precursor",
        "refseq_ac": [
            {
                "id": "NP_001373638",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373638",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tlr8b; TIR8.1",
        "gene_names_refseq": "TIR8.1; tlr8b",
        "protein_names_uniprotkb": "Toll-like receptor 8b precursor",
        "protein_names_refseq": "toll-like receptor 8b precursor",
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        "disease": "immunodeficiency 98 (Disease Ontology:DOID:0061068); COVID-19 (Disease Ontology:DOID:0080600); severe COVID-19 (Disease Ontology:DOID:0081013); anogenital venereal wart (Disease Ontology:DOID:11168); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); alcohol use disorder (Disease Ontology:DOID:1574); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); atopic dermatitis (Disease Ontology:DOID:3310); allergic rhinitis (Disease Ontology:DOID:4481); rhinitis (Disease Ontology:DOID:4483)",
        "pathway": " (dre:403136)",
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        "publication_id_list": "14687933;14687934;16552074;18248169;18495251;26509227;26743178;27084059;34544800;35159329",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01020234.1, SRR32588725.15390608.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Aug 31, 2020 this sequence version replaced XP_017213609.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 11,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M6Z347",
        "ec_number_list": [],
        "go_molecular_function": "GO:0038187 pattern recognition receptor activity",
        "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0032755 positive regulation of interleukin-6 production;GO:0007249 canonical NF-kappaB signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A2R8Q9M5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q9T0-1",
        "uniprot_id": [
            {
                "id": "A0A2R8Q9T0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q9T0",
                "type": "external"
            }
        ],
        "mass": 76018.0,
        "length": 672,
        "protein_name": "Bestrophin homolog",
        "gene_name": "best1",
        "organism": "Zebrafish",
        "refseq_name": "bestrophin-4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_689098",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689098",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "best1",
        "gene_names_refseq": "best1",
        "protein_names_uniprotkb": "Bestrophin homolog",
        "protein_names_refseq": "bestrophin-4 isoform X1",
        "tax_id": 7955,
        "disease": "vitelliform macular dystrophy (Disease Ontology:DOID:0050661); bestrophinopathy (Disease Ontology:DOID:0050662); retinitis pigmentosa 50 (Disease Ontology:DOID:0110396); autosomal dominant vitreoretinochoroidopathy (Disease Ontology:DOID:0111569); macular degeneration (Disease Ontology:DOID:4448)",
        "pathway": " (R-DRE-2672351)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_689098.2. COMPLETENESS: full length., [RefSeq]; Forms chloride channels., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 5,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7T7I3;A0AC58IWT3",
        "ec_number_list": [
            {
                "id": "7.6.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
                "type": "external"
            },
            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005254 chloride channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex",
        "go_biological_process": "GO:1902476 chloride transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8Q9T0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q9T1-1",
        "uniprot_id": [
            {
                "id": "A0A2R8Q9T1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q9T1",
                "type": "external"
            }
        ],
        "mass": 58462.0,
        "length": 540,
        "protein_name": "Thymocyte selection-associated high mobility group box protein TOX",
        "gene_name": "tox",
        "organism": "Zebrafish",
        "refseq_name": "thymocyte selection-associated high mobility group box protein TOX",
        "refseq_ac": [
            {
                "id": "NP_001243623",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243623",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tox; sb:eu868; si:ch211-198j13.2",
        "gene_names_refseq": "sb:eu868; si:ch211-198j13.2; tox",
        "protein_names_uniprotkb": "Thymocyte selection-associated high mobility group box protein TOX",
        "protein_names_refseq": "thymocyte selection-associated high mobility group box protein TOX",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569666)",
        "pathway_count": 1,
        "publication_count": 6,
        "publication_id_list": "24240475;26469318;27139488;27189481;28327131;28974511",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588734.3071832.1, SRR32588717.21880687.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Feb 17, 2012 this sequence version replaced XP_001919539.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; TOX is an HMG box-containing protein that has important roles in T-ALL initiation and maintenance. TOX inhibits the recruitment of KU70/KU80 to DNA breaks, thereby inhibiting NHEJ repair. Thus, TOX is likely a dominant oncogenic driver in a large fraction of human T-ALL and enhances genomic instability, [RefSeq, PubMed]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NZ21",
        "ec_number_list": [],
        "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0002521 leukocyte differentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A2R8Q9T1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8Q9U8-1",
        "uniprot_id": [
            {
                "id": "A0A2R8Q9U8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8Q9U8",
                "type": "external"
            }
        ],
        "mass": 40676.0,
        "length": 369,
        "protein_name": "Histamine H2 receptor",
        "gene_name": "hrh2a",
        "organism": "Zebrafish",
        "refseq_name": "histamine receptor H2a",
        "refseq_ac": [
            {
                "id": "NP_001038803",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038803",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hrh2a; hrh2",
        "gene_names_refseq": "hrh2a; hrh2",
        "protein_names_uniprotkb": "Histamine H2 receptor; Gastric receptor I",
        "protein_names_refseq": "histamine H2 receptor; histamine receptor H2a; histamine receptor H2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-390650)",
        "pathway_count": 1,
        "publication_count": 7,
        "publication_id_list": "17266939;20846403;21957242;28275716;32743878;33878430;37215570",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript is intronless :: BC162730.1, DQ647808.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 17, 2015 this sequence version replaced NP_001038803.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; G-protein coupled receptor for histamine, primarily mediating gastric acid secretion. Predominantly expressed in the gastric mucosa, couples to G(s) G alpha proteins upon histamine binding, leading to activation of adenylate cyclase and increased intracellular cyclic AMP (cAMP) levels. This signaling cascade stimulates parietal cells to secrete hydrochloric acid, playing a key role in digestive physiology. Also expressed in other tissues, including the heart and central nervous system, where it may contribute to cardiac stimulation and modulate neurotransmitter release., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NAH7;A0AC58H6U0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030594 neurotransmitter receptor activity;GO:0004969 histamine receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse",
        "go_biological_process": "GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "A0A2R8Q9U8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QAB1-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QAB1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QAB1",
                "type": "external"
            }
        ],
        "mass": 76595.0,
        "length": 693,
        "protein_name": "Cyclin-T2a isoform 1",
        "gene_name": "ccnt2a",
        "organism": "Zebrafish",
        "refseq_name": "cyclin-T2a isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001180310",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180310",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ccnt2a; ccnt2; cycT; wu:fi17h07; zgc:55357",
        "gene_names_refseq": "ccnt2a; ccnt2; cycT; wu:fi17h07; zgc:55357",
        "protein_names_uniprotkb": "Cyclin-T2a isoform 1",
        "protein_names_refseq": "cyclin T2; cyclin-T2a isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:327568);  (R-DRE-674695);  (R-DRE-6796648);  (R-DRE-6807505);  (R-DRE-75955)",
        "pathway_count": 5,
        "publication_count": 4,
        "publication_id_list": "21205313;21468032;26469318;28318412",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1810267.1, GFIL01005663.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1, BM776488.1 and EB771057.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NUM2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0008024 cyclin/CDK positive transcription elongation factor complex",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0032786 positive regulation of DNA-templated transcription, elongation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A2R8QAB1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QAU3-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QAU3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QAU3",
                "type": "external"
            }
        ],
        "mass": 21671.0,
        "length": 183,
        "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP3",
        "gene_name": "imp3",
        "organism": "Zebrafish",
        "refseq_name": "U3 small nucleolar ribonucleoprotein IMP3",
        "refseq_ac": [
            {
                "id": "NP_001278286",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278286",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "imp3; zgc:56526",
        "gene_names_refseq": "imp3; zgc:56526",
        "protein_names_uniprotkb": "U3 small nucleolar ribonucleoprotein protein IMP3; U3 small nucleolar ribonucleoprotein protein imp3",
        "protein_names_refseq": "IMP3, U3 small nucleolar ribonucleoprotein, homolog; U3 small nucleolar ribonucleoprotein IMP3",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:393237)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "27189481;27898262;30773582",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH493453.1, EH587565.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505377, SAMEA4476734 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH493453.1, EH466588.1 and EH598772.1., [RefSeq]; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "pathway": " (dre:101885604);  (R-DRE-375276);  (R-DRE-418594);  (R-DRE-6798695);  (R-DRE-977606)",
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        "gene_names_refseq": "fb33h10; gga1; im:6912200; wu:fb33h10; zgc:101044",
        "protein_names_uniprotkb": "ADP-ribosylation factor-binding protein GGA1",
        "protein_names_refseq": "ADP-ribosylation factor-binding protein GGA1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:798361);  (R-DRE-8854214)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "27189481;34329618",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC080229.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH435716.1, BC155255.1, CT736351.2, EB911367.1 and CR626864.10. On Nov 13, 2008 this sequence version replaced NP_001004000.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N1X2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0031267 small GTPase binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding",
        "go_cellular_component": "GO:0031901 early endosome membrane;GO:0005802 trans-Golgi network",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034394 protein localization to cell surface;GO:0006893 Golgi to plasma membrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A2R8QEJ6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QFJ7-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QFJ7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QFJ7",
                "type": "external"
            }
        ],
        "mass": 70945.0,
        "length": 651,
        "protein_name": "High affinity cationic amino acid transporter 1 isoform X1",
        "gene_name": "slc7a1a",
        "organism": "Zebrafish",
        "refseq_name": "high affinity cationic amino acid transporter 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021327949",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327949",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc7a1a",
        "gene_names_refseq": "slc7a1a",
        "protein_names_uniprotkb": "High affinity cationic amino acid transporter 1 isoform X1",
        "protein_names_refseq": "high affinity cationic amino acid transporter 1 isoform X1",
        "tax_id": 7955,
        "disease": "proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Disease Ontology:DOID:0111666)",
        "pathway": " (dre:559627)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M9Q3A9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000064 L-ornithine transmembrane transporter activity;GO:0015189 L-lysine transmembrane transporter activity;GO:0061459 L-arginine transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0097638 L-arginine import across plasma membrane;GO:1903352 L-ornithine transmembrane transport",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A2R8QFJ7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QFS1-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QFS1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QFS1",
                "type": "external"
            }
        ],
        "mass": 28601.0,
        "length": 257,
        "protein_name": "H-2 class II histocompatibility antigen, A-Q alpha chain",
        "gene_name": "mhc2d8.35a1",
        "organism": "Zebrafish",
        "refseq_name": "H-2 class II histocompatibility antigen, A-Q alpha chain",
        "refseq_ac": [
            {
                "id": "XP_009302401",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302401",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mhc2d8.35a1",
        "gene_names_refseq": "mhc2d8.35a1",
        "protein_names_uniprotkb": "H-2 class II histocompatibility antigen, A-Q alpha chain",
        "protein_names_refseq": "H-2 class II histocompatibility antigen, A-Q alpha chain",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:795595);  (R-DRE-2132295)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "reported_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M3B254",
        "ec_number_list": [],
        "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding",
        "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex",
        "go_biological_process": "GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0002250 adaptive immune response;GO:0050870 positive regulation of T cell activation;GO:0050778 positive regulation of immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8QFS1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QFV4-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QFV4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QFV4",
                "type": "external"
            }
        ],
        "mass": 37354.0,
        "length": 333,
        "protein_name": "Phytanoyl-CoA hydroxylase-interacting protein",
        "gene_name": "phyhip",
        "organism": "Zebrafish",
        "refseq_name": "phytanoyl-CoA hydroxylase-interacting protein",
        "refseq_ac": [
            {
                "id": "NP_001314897",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314897",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "phyhip",
        "gene_names_refseq": "phyhip",
        "protein_names_uniprotkb": "Phytanoyl-CoA hydroxylase-interacting protein; Phytanoyl-CoA hydroxylase-associated protein 1",
        "protein_names_refseq": "phytanoyl-CoA hydroxylase-interacting protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100002455)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01014915.1, EH441145.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000008.1. On Jun 1, 2016 this sequence version replaced XP_001342239.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Its interaction with PHYH suggests a role in the development of the central system., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1P435",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A2R8QFV4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QFW3-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QFW3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QFW3",
                "type": "external"
            }
        ],
        "mass": 24069.0,
        "length": 211,
        "protein_name": "Peroxisomal membrane protein 4",
        "gene_name": "pxmp4",
        "organism": "Zebrafish",
        "refseq_name": "peroxisomal membrane protein 4",
        "refseq_ac": [
            {
                "id": "NP_001313485",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313485",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pxmp4; fe02h09; wu:fe02h09",
        "gene_names_refseq": "fe02h09; pxmp4; wu:fe02h09",
        "protein_names_uniprotkb": "Peroxisomal membrane protein 4",
        "protein_names_refseq": "peroxisomal membrane protein 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:566065);  (R-DRE-9603798)",
        "pathway_count": 2,
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        "publication_id_list": "27189481;35295584",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH585627.1, SRR32588726.57833740.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH585627.1, EH496662.1 and JBMGRA010000006.1. On May 20, 2016 this sequence version replaced XP_694422.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P941",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005778 peroxisomal membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A2R8QFW3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QGC0-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QGC0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QGC0",
                "type": "external"
            }
        ],
        "mass": 44252.0,
        "length": 398,
        "protein_name": "Ubiquitin-like modifier-activating enzyme 5",
        "gene_name": "uba5",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin-like modifier-activating enzyme 5",
        "refseq_ac": [
            {
                "id": "NP_001292546",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292546",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "uba5; cb972; ube1dc1",
        "gene_names_refseq": "cb972; uba5; ube1dc1",
        "protein_names_uniprotkb": "Ubiquitin-like modifier-activating enzyme 5; UFM1-activating enzyme",
        "protein_names_refseq": "UFM1-activating enzyme; ubiquitin-activating enzyme 5; ubiquitin-activating enzyme E1-domain containing 1; ubiquitin-like modifier-activating enzyme 5",
        "tax_id": 7955,
        "disease": "early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); developmental and epileptic encephalopathy 44 (Disease Ontology:DOID:0080424); autosomal recessive spinocerebellar ataxia 24 (Disease Ontology:DOID:0111615)",
        "pathway": " (dre:386712)",
        "pathway_count": 1,
        "publication_count": 7,
        "publication_id_list": "25014315;26469318;27189481;27545681;28252024;35134494;38046095",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01000279.1, GDQQ01014402.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Mar 21, 2015 this sequence version replaced XP_691141.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments., [RefSeq]; Clinical, biochemical, and experimental findings support our finding of UBA5 mutations as a pathophysiological cause for early-onset encephalopathies due to abnormal protein ufmylation, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1P6X7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008641 ubiquitin-like modifier activating enzyme activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007626 locomotory behavior;GO:0036269 swimming behavior;GO:0010821 regulation of mitochondrion organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
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        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RJH6-1",
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            {
                "id": "A0A2R8RJH6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RJH6",
                "type": "external"
            }
        ],
        "mass": 23427.0,
        "length": 211,
        "protein_name": "Guanylate kinase",
        "gene_name": "guk1a",
        "organism": "Zebrafish",
        "refseq_name": "guanylate kinase isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001303825",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303825",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "guk1a; sb:cb295; zgc:86776",
        "gene_names_refseq": "guk1a; sb:cb295; zgc:86776",
        "protein_names_uniprotkb": "Guanylate kinase; 2.7.4.8; GMP kinase",
        "protein_names_refseq": "guanylate kinase isoform 1",
        "tax_id": 7955,
        "disease": "mitochondrial DNA depletion syndrome-21 (Disease Ontology:DOID:0051029)",
        "pathway": " (dre:415216)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.544391.1, SRR32588733.53922.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505385 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1, CN504301.1, EH437861.1, EH463832.1 and AA497237.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P7T4",
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            {
                "id": "2.7.4.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.8",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004385 GMP kinase activity;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0001917 photoreceptor inner segment",
        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8QHC0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QHC0",
                "type": "external"
            }
        ],
        "mass": 34619.0,
        "length": 309,
        "protein_name": "T-cell leukemia homeobox protein 2 isoform X1",
        "gene_name": "tlx2",
        "organism": "Zebrafish",
        "refseq_name": "T-cell leukemia homeobox protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005173139",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173139",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tlx2; Tlx-3a; hox11l; tlx3a; tlxA",
        "gene_names_refseq": "Tlx-3a; hox11l; tlx2; tlx3a; tlxA",
        "protein_names_uniprotkb": "T-cell leukemia homeobox protein 2 isoform X1",
        "protein_names_refseq": "T-cell leukemia homeobox protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "intestinal pseudo-obstruction (Disease Ontology:DOID:0080072)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048839 inner ear development;GO:0048513 animal organ development",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8QHD8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QHD8",
                "type": "external"
            }
        ],
        "mass": 22213.0,
        "length": 198,
        "protein_name": "Deubiquitinase DESI2",
        "gene_name": "LOC794838",
        "organism": "Zebrafish",
        "refseq_name": "deubiquitinase DESI2 isoform X2",
        "refseq_ac": [
            {
                "id": "XP_003199796",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199796",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC794838",
        "gene_names_refseq": "LOC794838",
        "protein_names_uniprotkb": "Deubiquitinase DESI2; 3.1.2.22; 3.4.19.12; Desumoylating isopeptidase 2; PPPDE peptidase domain-containing protein 1; Palmitoyl protein thioesterase DESI2; Protein FAM152A; S-depalmitoylase DESI2",
        "protein_names_refseq": "deubiquitinase DESI2 isoform X2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:794838)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1RSY7",
        "ec_number_list": [
            {
                "id": "3.1.2.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22",
                "type": "external"
            },
            {
                "id": "3.4.19.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            },
            {
                "id": "3.1.1.93",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.93",
                "type": "external"
            },
            {
                "id": "3.1.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008474 palmitoyl-(protein) hydrolase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0101005 deubiquitinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006508 proteolysis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8QHD8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QHQ6-1",
        "uniprot_id": [
            {
                "id": "IZUM1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QHQ6",
                "type": "external"
            }
        ],
        "mass": 38604.0,
        "length": 336,
        "protein_name": "Izumo sperm-egg fusion protein 1",
        "gene_name": "izumo1",
        "organism": "Zebrafish",
        "refseq_name": "izumo sperm-egg fusion protein 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001314727",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314727",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "izumo1",
        "gene_names_refseq": "izumo1",
        "protein_names_uniprotkb": "Izumo sperm-egg fusion protein 1",
        "protein_names_refseq": "izumo sperm-egg fusion protein 1 precursor; izumo sperm-egg fusion protein 1; izumo sperm-oocyte fusion 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100329365);  (R-DRE-1300645)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "23594743;39423812",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588728.9749069.1, SRR32588722.45851190.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000008.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Essential sperm cell-surface protein required for fertilization by acting as a ligand for bncr receptor on egg. The interaction of the complex izumo1:spaca6:tmemt81 with bncr is a necessary adhesion event between sperm and egg that is required for fertilization., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 2,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1P314",
        "ec_number_list": [],
        "go_molecular_function": "GO:0048018 receptor ligand activity;GO:0086080 protein binding involved in heterotypic cell-cell adhesion;GO:0005102 signaling receptor binding",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0002080 acrosomal membrane;GO:0016020 membrane",
        "go_biological_process": "GO:0035036 sperm-egg recognition;GO:0007339 binding of sperm to zona pellucida;GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A2R8QHQ6-1",
        "record_type": "protein",
        "filter_code": "0000000.0100101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QI63-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QI63_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QI63",
                "type": "external"
            }
        ],
        "mass": 91541.0,
        "length": 805,
        "protein_name": "Autophagy-related protein 9",
        "gene_name": "atg9b",
        "organism": "Zebrafish",
        "refseq_name": "autophagy-related protein 9B",
        "refseq_ac": [
            {
                "id": "NP_001307007",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001307007",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "atg9b; zgc:158872",
        "gene_names_refseq": "atg9b; zgc:158872",
        "protein_names_uniprotkb": "Autophagy-related protein 9",
        "protein_names_refseq": "ATG9 autophagy related 9 homolog B; autophagy-related protein 9B",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:791223)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "19221467;26469318;27189481;27467399;30399334;33343615;34071043;34439993;36042265;36232766",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.83288.1, GDQH01003490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505388, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments, RNA-seq data and orthologous data. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1P2W7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0017128 phospholipid scramblase activity",
        "go_cellular_component": "GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site",
        "go_biological_process": "GO:0034497 protein localization to phagophore assembly site;GO:0000423 mitophagy;GO:0034727 piecemeal microautophagy of the nucleus;GO:0061709 reticulophagy",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A2R8QI63-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8QI88-1",
        "uniprot_id": [
            {
                "id": "A0A2R8QI88_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QI88",
                "type": "external"
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        ],
        "mass": 224389.0,
        "length": 2005,
        "protein_name": "Pecanex-like protein",
        "gene_name": "pcnx2",
        "organism": "Zebrafish",
        "refseq_name": "pecanex-like protein 2 isoform X1",
        "refseq_ac": [
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        ],
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        "protein_names_uniprotkb": "Motile sperm domain-containing protein 2",
        "protein_names_refseq": "motile sperm domain-containing protein 2 isoform 1",
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                "id": "A0A2R8QLH1_DANRE",
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        "protein_name": "Ras-related protein Rab-41 isoform X3",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
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                "id": "3.6.1.-",
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                "id": "3.6.5.4",
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        "protein_name": "B-cell lymphoma/leukemia 11B isoform X1",
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        "protein_name": "Protein-serine/threonine kinase",
        "gene_name": "pdk3a",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_biological_process": "GO:0010906 regulation of glucose metabolic process;GO:0010510 regulation of pyruvate decarboxylation to acetyl-CoA",
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        "mass": 64497.0,
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        "protein_name": "Myc box-dependent-interacting protein 1b isoform 1",
        "gene_name": "bin1b",
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            {
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        "protein_names_uniprotkb": "Myc box-dependent-interacting protein 1b isoform 1",
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        "tax_id": 7955,
        "disease": "centronuclear myopathy 2 (Disease Ontology:DOID:0111220); prostate adenocarcinoma (Disease Ontology:DOID:2526); breast carcinoma (Disease Ontology:DOID:3459)",
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0008021 synaptic vesicle;GO:0005634 nucleus;GO:0005768 endosome;GO:0030424 axon",
        "go_biological_process": "GO:0060048 cardiac muscle contraction;GO:0033292 T-tubule organization;GO:0006897 endocytosis;GO:0051649 establishment of localization in cell;GO:0030154 cell differentiation",
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        ],
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        "length": 358,
        "protein_name": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1",
        "gene_name": "sirt3",
        "organism": "Zebrafish",
        "refseq_name": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009301762",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301762",
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            }
        ],
        "gene_names_uniprotkb": "sirt3; zgc:158774",
        "gene_names_refseq": "sirt3; zgc:158774",
        "protein_names_uniprotkb": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1",
        "protein_names_refseq": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1",
        "tax_id": 7955,
        "disease": "abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (R-DRE-2151201);  (R-DRE-9617629);  (R-DRE-9841251);  (R-DRE-9854311)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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            {
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        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0070403 NAD+ binding;GO:0017136 histone deacetylase activity, NAD-dependent;GO:0016740 transferase activity",
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    {
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        ],
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            {
                "id": "XP_005173191",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173191",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ctbp1; fa96d06; wu:fa96d06; zgc:136929",
        "gene_names_refseq": "ctbp1; fa96d06; wu:fa96d06; zgc:136929",
        "protein_names_uniprotkb": "C-terminal-binding protein 1 isoform X2",
        "protein_names_refseq": "C-terminal-binding protein 1 isoform X2",
        "tax_id": 7955,
        "disease": "alcohol use disorder (Disease Ontology:DOID:1574); primary ovarian insufficiency (Disease Ontology:DOID:5426)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0051287 NAD binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",
        "go_cellular_component": "GO:0005634 nucleus",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8QPY7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QPY7",
                "type": "external"
            }
        ],
        "mass": 41295.0,
        "length": 377,
        "protein_name": "Homeobox protein TGIF2",
        "gene_name": "tgif2",
        "organism": "Zebrafish",
        "refseq_name": "homeobox protein TGIF2",
        "refseq_ac": [
            {
                "id": "XP_005168761",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168761",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tgif2",
        "gene_names_refseq": "tgif2",
        "protein_names_uniprotkb": "Homeobox protein TGIF2",
        "protein_names_refseq": "homeobox protein TGIF2",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription",
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        "kg_view_protein": true
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    {
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            {
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                "type": "external"
            }
        ],
        "mass": 123921.0,
        "length": 1117,
        "protein_name": "Solute carrier family 12 member 7 isoform X1",
        "gene_name": "slc12a7a",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 12 member 7 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005171306",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171306",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc12a7a",
        "gene_names_refseq": "slc12a7a",
        "protein_names_uniprotkb": "Solute carrier family 12 member 7 isoform X1",
        "protein_names_refseq": "solute carrier family 12 member 7 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:558214);  (R-DRE-426117)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0015379 potassium:chloride symporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse",
        "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0006884 cell volume homeostasis;GO:1902476 chloride transmembrane transport;GO:0055075 potassium ion homeostasis;GO:1990573 potassium ion import across plasma membrane",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8QTZ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QTZ5",
                "type": "external"
            }
        ],
        "mass": 37992.0,
        "length": 356,
        "protein_name": "Protein FosB",
        "gene_name": "fosb",
        "organism": "Zebrafish",
        "refseq_name": "protein FosB",
        "refseq_ac": [
            {
                "id": "NP_001315131",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315131",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fosb; zgc:92354",
        "gene_names_refseq": "fosb; zgc:92354",
        "protein_names_uniprotkb": "Protein FosB",
        "protein_names_refseq": "FBJ murine osteosarcoma viral oncogene homolog B; protein FosB",
        "tax_id": 7955,
        "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); depressive disorder (Disease Ontology:DOID:1596); substance dependence (Disease Ontology:DOID:9973)",
        "pathway": " (dre:492346)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "25181277;25556858;25615886;26061167;26208853;37664458;38385270;39072972;39081296;39347412",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.793094.1, SRR32588733.480147.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505385, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH434631.1, JBMGRA010000018.1 and EH460635.1. On Jun 9, 2016 this sequence version replaced XP_009292052.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0A8M1PA30",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0003690 double-stranded DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A2R8QTZ5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A2R8QUQ1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8QUQ1",
                "type": "external"
            }
        ],
        "mass": 56062.0,
        "length": 480,
        "protein_name": "Regulator of G-protein signaling 9a",
        "gene_name": "rgs9a",
        "organism": "Zebrafish",
        "refseq_name": "regulator of G-protein signaling 9a",
        "refseq_ac": [
            {
                "id": "NP_001314729",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314729",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rgs9a; rgs9; wipi1; zgc:152760",
        "gene_names_refseq": "rgs9a; rgs9; wipi1; zgc:152760",
        "protein_names_uniprotkb": "Regulator of G-protein signaling 9a",
        "protein_names_refseq": "WD repeat domain, phosphoinositide interacting 1; regulator of G-protein signaling 9a; regulator of G-protein signaling 9",
        "tax_id": 7955,
        "disease": "bradyopsia 1 (Disease Ontology:DOID:0070363)",
        "pathway": " (dre:767636)",
        "pathway_count": 1,
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        "publication_id_list": "24613356;26427652;26469318;32033529;34550876;35372349",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.8700352.1, SRR32588714.7305599.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On May 26, 2016 this sequence version replaced XP_005164102.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P8B2;A0AC58IZN6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005096 GTPase activator activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0043005 neuron projection",
        "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007212 G protein-coupled dopamine receptor signaling pathway;GO:0009968 negative regulation of signal transduction;GO:0008277 regulation of G protein-coupled receptor signaling pathway",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RHK7-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RHK7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RHK7",
                "type": "external"
            }
        ],
        "mass": 40906.0,
        "length": 358,
        "protein_name": "DNA repair protein XRCC4",
        "gene_name": "xrcc4",
        "organism": "Zebrafish",
        "refseq_name": "DNA repair protein XRCC4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009303957",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303957",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "xrcc4; zgc:73312",
        "gene_names_refseq": "xrcc4; zgc:73312",
        "protein_names_uniprotkb": "DNA repair protein XRCC4; X-ray repair cross-complementing protein 4",
        "protein_names_refseq": "DNA repair protein XRCC4 isoform X1",
        "tax_id": 7955,
        "disease": "salivary gland carcinoma (Disease Ontology:DOID:0050904); salivary gland adenoid cystic carcinoma (Disease Ontology:DOID:4866); multiple myeloma (Disease Ontology:DOID:9538)",
        "pathway": " (R-DRE-3108214);  (R-DRE-5693571)",
        "pathway_count": 2,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as an activator of the phospholipid scramblase activity of XKR4. This form, which is generated upon caspase-3 (CASP3) cleavage, translocates into the cytoplasm and interacts with XKR4, thereby promoting phosphatidylserine scramblase activity of XKR4 and leading to phosphatidylserine exposure on apoptotic cell surface., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3B6L4",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding",
        "go_cellular_component": "GO:0032807 DNA ligase IV complex;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex",
        "go_biological_process": "GO:0006303 double-strand break repair via nonhomologous end joining;GO:0010165 response to X-ray;GO:0033152 immunoglobulin V(D)J recombination",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RHK7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RI02-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RI02_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RI02",
                "type": "external"
            }
        ],
        "mass": 36601.0,
        "length": 337,
        "protein_name": "Ephrin-B3",
        "gene_name": "efnb3a",
        "organism": "Zebrafish",
        "refseq_name": "ephrin-B2a",
        "refseq_ac": [
            {
                "id": "XP_692670",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692670",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "efnb3a",
        "gene_names_refseq": "efnb3a",
        "protein_names_uniprotkb": "Ephrin-B3",
        "protein_names_refseq": "ephrin-B2a",
        "tax_id": 7955,
        "disease": "movement disease (Disease Ontology:DOID:480)",
        "pathway": " (dre:564234)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_692670.1. COMPLETENESS: full length., [RefSeq]; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7TF59",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046875 ephrin receptor binding",
        "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0042734 presynaptic membrane",
        "go_biological_process": "GO:0007267 cell-cell signaling;GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance",
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        "record_id": "A0A2R8RI02-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RJ22-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RJ22_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RJ22",
                "type": "external"
            }
        ],
        "mass": 122466.0,
        "length": 1065,
        "protein_name": "Anoctamin",
        "gene_name": "ano2b",
        "organism": "Zebrafish",
        "refseq_name": "anoctamin-2b",
        "refseq_ac": [
            {
                "id": "NP_001314787",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314787",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ano2b; ano2; si:dkey-224k5.2; tmem16b",
        "gene_names_refseq": "ano2b; ano2; si:dkey-224k5.2; tmem16b",
        "protein_names_uniprotkb": "Anoctamin",
        "protein_names_refseq": "anoctamin 2; anoctamin-2b; transmembrane protein 16B",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:566373);  (R-DRE-2672351)",
        "pathway_count": 2,
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        "publication_id_list": "24753112;26116173;27189481;28619821;30631052;35226401",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.37584082.1, SRR32588719.5042411.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476820, SAMEA898404 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000004.1. On May 27, 2016 this sequence version replaced XP_009298252.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "reported_n_glycosites": 0,
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1P9F5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0005229 intracellularly calcium-gated chloride channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:1902476 chloride transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A2R8RJ22-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8RJX3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RJX3",
                "type": "external"
            }
        ],
        "mass": 52147.0,
        "length": 461,
        "protein_name": "Leiomodin-3",
        "gene_name": "lmod2a",
        "organism": "Zebrafish",
        "refseq_name": "leiomodin-2a",
        "refseq_ac": [
            {
                "id": "NP_001004616",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004616",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lmod2a; zgc:103424",
        "gene_names_refseq": "lmod2a; zgc:103424",
        "protein_names_uniprotkb": "Leiomodin-3",
        "protein_names_refseq": "leiomodin-2a",
        "tax_id": 7955,
        "disease": "dilated cardiomyopathy 2G (Disease Ontology:DOID:0081163); dilated cardiomyopathy (Disease Ontology:DOID:12930)",
        "pathway": " (dre:447877)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "27189481;29400650",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: CO935248.1, BC081475.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476740, SAMEA4476744 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Jun 4, 2024 this sequence version replaced XP_005163172.1, NP_001004616.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2BAA0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding;GO:0005523 tropomyosin binding",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005865 striated muscle thin filament;GO:0031430 M band;GO:0030016 myofibril",
        "go_biological_process": "GO:0006936 muscle contraction;GO:0007015 actin filament organization;GO:0051694 pointed-end actin filament capping;GO:0030239 myofibril assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A2R8RJX3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RJY3-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RJY3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RJY3",
                "type": "external"
            }
        ],
        "mass": 33920.0,
        "length": 303,
        "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog",
        "gene_name": "vta1",
        "organism": "Zebrafish",
        "refseq_name": "vacuolar protein sorting-associated protein VTA1 homolog isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005160712",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160712",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "vta1; c6orf55; wu:fb08c11; zgc:64104",
        "gene_names_refseq": "c6orf55; vta1; wu:fb08c11; zgc:64104",
        "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein VTA1 homolog",
        "protein_names_refseq": "vacuolar protein sorting-associated protein VTA1 homolog isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-917729)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M2B7S2",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0010008 endosome membrane;GO:0005771 multivesicular body",
        "go_biological_process": "GO:0015031 protein transport;GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RJY3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RK92-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RK92_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RK92",
                "type": "external"
            }
        ],
        "mass": 32409.0,
        "length": 292,
        "protein_name": "Secreted frizzled-related protein 1",
        "gene_name": "LOC101884738",
        "organism": "Zebrafish",
        "refseq_name": "secreted frizzled-related protein 5 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005174172",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174172",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC101884738",
        "gene_names_refseq": "LOC101884738",
        "protein_names_uniprotkb": "Secreted frizzled-related protein 1",
        "protein_names_refseq": "secreted frizzled-related protein 5 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101884738)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2BLH1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0017147 Wnt-protein binding",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0030154 cell differentiation;GO:0060070 canonical Wnt signaling pathway;GO:0035567 non-canonical Wnt signaling pathway;GO:2000026 regulation of multicellular organismal development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RK92-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RKX9-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RKX9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RKX9",
                "type": "external"
            }
        ],
        "mass": 37387.0,
        "length": 340,
        "protein_name": "Guanine nucleotide binding protein (G protein), beta polypeptide 4b isoform X1",
        "gene_name": "gnb4b",
        "organism": "Zebrafish",
        "refseq_name": "guanine nucleotide binding protein (G protein), beta polypeptide 4b",
        "refseq_ac": [
            {
                "id": "NP_001429080",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429080",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gnb4b; zgc:101614",
        "gene_names_refseq": "gnb4b; zgc:101614",
        "protein_names_uniprotkb": "Guanine nucleotide binding protein (G protein), beta polypeptide 4b isoform X1",
        "protein_names_refseq": "guanine nucleotide binding protein (G protein), beta polypeptide 4b",
        "tax_id": 7955,
        "disease": "Charcot-Marie-Tooth disease dominant intermediate F (Disease Ontology:DOID:0110206)",
        "pathway": " (R-DRE-202040);  (R-DRE-381676);  (R-DRE-392170);  (R-DRE-400042);  (R-DRE-416476);  (R-DRE-418594);  (R-DRE-418597);  (R-DRE-420092);  (R-DRE-428930);  (R-DRE-432040);  (R-DRE-456926);  (R-DRE-6814122);  (R-DRE-9856530)",
        "pathway_count": 13,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01001758.1, SRR32588734.386786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jul 28, 2025 this sequence version replaced XP_021335278.1., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M9Q765",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030159 signaling receptor complex adaptor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RKX9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RL46-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RL46_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RL46",
                "type": "external"
            }
        ],
        "mass": 52540.0,
        "length": 471,
        "protein_name": "U3 small nucleolar RNA-interacting protein 2",
        "gene_name": "rrp9",
        "organism": "Zebrafish",
        "refseq_name": "U3 small nucleolar RNA-interacting protein 2",
        "refseq_ac": [
            {
                "id": "NP_001112367",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001112367",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rrp9; rnu3ip2",
        "gene_names_refseq": "rnu3ip2; rrp9",
        "protein_names_uniprotkb": "U3 small nucleolar RNA-interacting protein 2; RRP9 homolog; U3 small nucleolar ribonucleoprotein-associated 55 kDa protein",
        "protein_names_refseq": "RNA, U3 small nucleolar interacting protein 2; U3 small nucleolar RNA-interacting protein 2; ribosomal RNA processing 9, small subunit (SSU) processome component, homolog",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:402808)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "24633177",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588716.14873553.1, SRR26395062.658791.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000011.1. On Jun 7, 2025 this sequence version replaced NP_001112367.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NI67",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030515 snoRNA binding;GO:0034511 U3 snoRNA binding",
        "go_cellular_component": "GO:0032040 small-subunit processome",
        "go_biological_process": "GO:0006364 rRNA processing",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A2R8RL46-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RMT5-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RMT5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RMT5",
                "type": "external"
            }
        ],
        "mass": 117364.0,
        "length": 1018,
        "protein_name": "Importin-8 isoform X1",
        "gene_name": "ipo8",
        "organism": "Zebrafish",
        "refseq_name": "importin-8 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005164639",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164639",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ipo8; Imp8; si:ch211-116i17.1",
        "gene_names_refseq": "Imp8; ipo8; si:ch211-116i17.1",
        "protein_names_uniprotkb": "Importin-8 isoform X1",
        "protein_names_refseq": "importin-8 isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M2BBQ6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0031267 small GTPase binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0030513 positive regulation of BMP signaling pathway;GO:0009953 dorsal/ventral pattern formation;GO:0080154 regulation of fertilization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RMT5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RQN4-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RQN4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RQN4",
                "type": "external"
            }
        ],
        "mass": 59979.0,
        "length": 533,
        "protein_name": "Interferon-gamma-inducible GTPase 10 isoform X1",
        "gene_name": "LOC100333286",
        "organism": "Zebrafish",
        "refseq_name": "interferon-gamma-inducible GTPase 10 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290589",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290589",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100333286",
        "gene_names_refseq": "LOC100333286",
        "protein_names_uniprotkb": "Interferon-gamma-inducible GTPase 10 isoform X1",
        "protein_names_refseq": "interferon-gamma-inducible GTPase 10 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100333286)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "secondary_ac_list": "A0A8M3AJ41",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005525 GTP binding;GO:0016787 hydrolase activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A2R8RQN4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A2R8RSJ1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RSJ1",
                "type": "external"
            }
        ],
        "mass": 56729.0,
        "length": 503,
        "protein_name": "Atrial natriuretic peptide receptor 3 isoform X1",
        "gene_name": "npr3",
        "organism": "Zebrafish",
        "refseq_name": "atrial natriuretic peptide receptor 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005165413",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165413",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "npr3; im:7138418; si:dkey-199l1.2; zgc:158440",
        "gene_names_refseq": "im:7138418; npr3; si:dkey-199l1.2; zgc:158440",
        "protein_names_uniprotkb": "Atrial natriuretic peptide receptor 3 isoform X1",
        "protein_names_refseq": "atrial natriuretic peptide receptor 3 isoform X1",
        "tax_id": 7955,
        "disease": "bone disease (Disease Ontology:DOID:0080001); hypertension (Disease Ontology:DOID:10763)",
        "pathway": " (dre:569395)",
        "pathway_count": 1,
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        "publication_id_list": "24353062;27993976;30018004;36791723;37629102",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0017046 peptide hormone binding;GO:0016941 natriuretic peptide receptor activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0007165 signal transduction;GO:0060038 cardiac muscle cell proliferation",
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        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8RT44_DANRE",
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            }
        ],
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        "length": 763,
        "protein_name": "Bardet-Biedl syndrome 12 protein",
        "gene_name": "bbs12",
        "organism": "Zebrafish",
        "refseq_name": "chaperonin-containing T-complex member BBS12",
        "refseq_ac": [
            {
                "id": "NP_001373228",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373228",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bbs12",
        "gene_names_refseq": "bbs12",
        "protein_names_uniprotkb": "Bardet-Biedl syndrome 12 protein",
        "protein_names_refseq": "chaperonin-containing T-complex member BBS12",
        "tax_id": 7955,
        "disease": "Bardet-Biedl syndrome 12 (Disease Ontology:DOID:0110134)",
        "pathway": " (dre:570583)",
        "pathway_count": 1,
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        "publication_id_list": "17160889;18381349;20498079;21258341;27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC124453.1, GFIL01002215.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Aug 19, 2020 this sequence version replaced XP_002667252.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005524 ATP binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0045494 photoreceptor cell maintenance;GO:0007369 gastrulation;GO:0051131 chaperone-mediated protein complex assembly;GO:0060027 convergent extension involved in gastrulation",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8RTN4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RTN4",
                "type": "external"
            }
        ],
        "mass": 109699.0,
        "length": 955,
        "protein_name": "Toll-like receptor 22 precursor",
        "gene_name": "tlr22",
        "organism": "Zebrafish",
        "refseq_name": "toll-like receptor 22 precursor",
        "refseq_ac": [
            {
                "id": "NP_001122147",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122147",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tlr22; TLR21.2",
        "gene_names_refseq": "TLR21.2; tlr22",
        "protein_names_uniprotkb": "Toll-like receptor 22 precursor",
        "protein_names_refseq": "toll-like receptor 22 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:403135)",
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        "publication_count": 10,
        "publication_id_list": "14687933;14687934;16552074;17804254;18248169;33242567;34130754;34428400;38055273;38882496",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01005545.1, SRR32588731.357188.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505386 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On or before Jan 30, 2016 this sequence version replaced XP_009293899.1, NP_001122147.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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    {
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            {
                "id": "A0A2R8RTX5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RTX5",
                "type": "external"
            }
        ],
        "mass": 69777.0,
        "length": 617,
        "protein_name": "Metastasis-associated protein MTA1 isoform X1",
        "gene_name": "mta1",
        "organism": "Zebrafish",
        "refseq_name": "metastasis-associated protein MTA1 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158917",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "mta1",
        "gene_names_refseq": "mta1",
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        "protein_names_refseq": "metastasis-associated protein MTA1 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:794477);  (R-DRE-3214815);  (R-DRE-3232118);  (R-DRE-8943724);  (R-DRE-9937850);  (R-DRE-9940951)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016581 NuRD complex;GO:0005634 nucleus",
        "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006302 double-strand break repair;GO:0010212 response to ionizing radiation;GO:0006355 regulation of DNA-templated transcription",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A2R8RTX5-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0A2R8RVE2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RVE2",
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        ],
        "mass": 81189.0,
        "length": 710,
        "protein_name": "Thimet oligopeptidase",
        "gene_name": "nln",
        "organism": "Zebrafish",
        "refseq_name": "neurolysin, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005155624",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155624",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nln; zgc:92589",
        "gene_names_refseq": "nln; zgc:92589",
        "protein_names_uniprotkb": "Thimet oligopeptidase; 3.4.24.15",
        "protein_names_refseq": "neurolysin, mitochondrial isoform X1",
        "tax_id": 7955,
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        "pathway": " (R-DRE-375276)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2B1S5",
        "ec_number_list": [
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                "id": "3.4.24.15",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.15",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006508 proteolysis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RVE2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RVN3-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RVN3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RVN3",
                "type": "external"
            }
        ],
        "mass": 168416.0,
        "length": 1526,
        "protein_name": "DNA topoisomerase 2-binding protein 1",
        "gene_name": "topbp1",
        "organism": "Zebrafish",
        "refseq_name": "DNA topoisomerase 2-binding protein 1",
        "refseq_ac": [
            {
                "id": "NP_001186667",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186667",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "topbp1",
        "gene_names_refseq": "topbp1",
        "protein_names_uniprotkb": "DNA topoisomerase 2-binding protein 1",
        "protein_names_refseq": "DNA topoisomerase 2-binding protein 1; topoisomerase (DNA) II binding protein 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:407679);  (R-DRE-5685938);  (R-DRE-5693607);  (R-DRE-6804756);  (R-DRE-69473)",
        "pathway_count": 5,
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        "publication_id_list": "24240475;26131719;26469318;27189481;34390914;35568694",
        "class_list": "",
        "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA4476796, SAMEA898401 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0140463 chromatin-protein adaptor activity",
        "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005694 chromosome;GO:0070532 BRCA1-B complex",
        "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0060216 definitive hemopoiesis;GO:0006270 DNA replication initiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A2R8RVN3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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                "url": "https://www.uniprot.org/uniprot/A0A2R8RWC4",
                "type": "external"
            }
        ],
        "mass": 60982.0,
        "length": 577,
        "protein_name": "TSC22 domain family protein 2 isoform X1",
        "gene_name": "tsc22d2",
        "organism": "Zebrafish",
        "refseq_name": "TSC22 domain family protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009294776",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294776",
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            }
        ],
        "gene_names_uniprotkb": "tsc22d2; cb869; id:ibd5097; kiaa0669; wu:fa55e04; zgc:92475",
        "gene_names_refseq": "cb869; id:ibd5097; kiaa0669; tsc22d2; wu:fa55e04; zgc:92475",
        "protein_names_uniprotkb": "TSC22 domain family protein 2 isoform X1",
        "protein_names_refseq": "TSC22 domain family protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M3B5S8",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8RWC4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8RWY8-1",
        "uniprot_id": [
            {
                "id": "A0A2R8RWY8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8RWY8",
                "type": "external"
            }
        ],
        "mass": 81760.0,
        "length": 714,
        "protein_name": "Zinc finger protein 710",
        "gene_name": "znf710a",
        "organism": "Zebrafish",
        "refseq_name": "zinc finger protein 710a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005159223",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159223",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "znf710a; fi04b07; wu:fi04b07; zgc:66441",
        "gene_names_refseq": "fi04b07; wu:fi04b07; zgc:66441; znf710a",
        "protein_names_uniprotkb": "Zinc finger protein 710",
        "protein_names_refseq": "zinc finger protein 710a isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2B631",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A2R8RWY8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8S035-1",
        "uniprot_id": [
            {
                "id": "A0A2R8S035_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8S035",
                "type": "external"
            }
        ],
        "mass": 15640.0,
        "length": 139,
        "protein_name": "Trafficking protein particle complex subunit 2-like protein",
        "gene_name": "trappc2l",
        "organism": "Zebrafish",
        "refseq_name": "trafficking protein particle complex subunit 2-like protein",
        "refseq_ac": [
            {
                "id": "NP_001003506",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003506",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "trappc2l; zgc:172319; zgc:92446",
        "gene_names_refseq": "trappc2l; zgc:172319; zgc:92446",
        "protein_names_uniprotkb": "Trafficking protein particle complex subunit 2-like protein",
        "protein_names_refseq": "trafficking protein particle complex 2-like; trafficking protein particle complex subunit 2-like protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:445112);  (R-DRE-204005);  (R-DRE-8876198)",
        "pathway_count": 3,
        "publication_count": 2,
        "publication_id_list": "12477932;21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH444997.1, EH456332.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH444997.1 and BQ132634.1. On Nov 18, 2009 this sequence version replaced NP_001003506.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
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        "reported_phosphosites": 0,
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        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1N1A9",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0030008 TRAPP complex",
        "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0A2R8S035-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8S0A2-1",
        "uniprot_id": [
            {
                "id": "A0A2R8S0A2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8S0A2",
                "type": "external"
            }
        ],
        "mass": 42514.0,
        "length": 389,
        "protein_name": "ELAV-like protein",
        "gene_name": "elavl2",
        "organism": "Zebrafish",
        "refseq_name": "ELAV-like protein 2",
        "refseq_ac": [
            {
                "id": "NP_001002172",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002172",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "elavl2; zgc:91918",
        "gene_names_refseq": "elavl2; zgc:91918",
        "protein_names_uniprotkb": "ELAV-like protein",
        "protein_names_refseq": "ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); ELAV like neuron-specific RNA binding protein 2; ELAV-like protein 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:431719)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "21337467;21695151;24735541;25434820;27189481;28252024;28381614;30695021;35065906;36417881",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC072716.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB918439.1 and BC072716.1. On Dec 28, 2011 this sequence version replaced NP_001002172.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Data show that hub RNA is a target of global miRNA-mediated repression, while the RNA-binding protein Dead end (Dnd) contributes to maintenance of the expression in the primordial germ cells (PGCs)., [RefSeq, PubMed]; That DAZL specifically binds the HuB 3'UTR and protects the message from degradation and/or enhances HuB translation, leading to the germ cell specific expression of HuB protein., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_s_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1N038",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0140517 protein-RNA adaptor activity",
        "go_cellular_component": "GO:1990904 ribonucleoprotein complex",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A2R8S0A2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R8S0G3-1",
        "uniprot_id": [
            {
                "id": "A0A2R8S0G3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R8S0G3",
                "type": "external"
            }
        ],
        "mass": 31044.0,
        "length": 277,
        "protein_name": "Phospholipid scramblase",
        "gene_name": "si:ch211-71m22.5",
        "organism": "Zebrafish",
        "refseq_name": "si:ch211-71m22.5",
        "refseq_ac": [
            {
                "id": "NP_001429444",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429444",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-71m22.5",
        "gene_names_refseq": "si:ch211-71m22.5",
        "protein_names_uniprotkb": "Phospholipid scramblase",
        "protein_names_refseq": "si:ch211-71m22.5",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564785)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.34904761.1, SRR32588730.18994690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Aug 11, 2025 this sequence version replaced XP_693207.5., [RefSeq]; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8N7TBA2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0017128 phospholipid scramblase activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0017121 plasma membrane phospholipid scrambling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R8S0G3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R9YJL3-1",
        "uniprot_id": [
            {
                "id": "A0A2R9YJL3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R9YJL3",
                "type": "external"
            }
        ],
        "mass": 202854.0,
        "length": 1762,
        "protein_name": "Adenylate kinase 9 isoform X1",
        "gene_name": "ak9",
        "organism": "Zebrafish",
        "refseq_name": "adenylate kinase 9 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_685909",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685909",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ak9",
        "gene_names_refseq": "ak9",
        "protein_names_uniprotkb": "Adenylate kinase 9 isoform X1",
        "protein_names_refseq": "adenylate kinase 9 isoform X1",
        "tax_id": 7955,
        "disease": "spermatogenic failure 89 (Disease Ontology:DOID:0070588); normal pressure hydrocephalus (Disease Ontology:DOID:1572)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_685909.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8N7T768",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0033862 UMP kinase activity;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0003341 cilium movement;GO:0006225 UDP biosynthetic process;GO:0046705 CDP biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R9YJL3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R9YJL7-1",
        "uniprot_id": [
            {
                "id": "A0A2R9YJL7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R9YJL7",
                "type": "external"
            }
        ],
        "mass": 128237.0,
        "length": 1153,
        "protein_name": "Metabotropic glutamate receptor 1",
        "gene_name": "grm1a",
        "organism": "Zebrafish",
        "refseq_name": "metabotropic glutamate receptor 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002665785",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665785",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "grm1a",
        "gene_names_refseq": "grm1a",
        "protein_names_uniprotkb": "Metabotropic glutamate receptor 1",
        "protein_names_refseq": "metabotropic glutamate receptor 1 isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive spinocerebellar ataxia 13 (Disease Ontology:DOID:0080062); spinocerebellar ataxia 44 (Disease Ontology:DOID:0080286); uveal melanoma (Disease Ontology:DOID:6039); skin melanoma (Disease Ontology:DOID:8923)",
        "pathway": " (dre:555576);  (R-DRE-416476);  (R-DRE-420499);  (R-DRE-6794361)",
        "pathway_count": 4,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002665785.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 4,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RMJ3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential;GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration;GO:0004930 G protein-coupled receptor activity;GO:0008066 glutamate receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0098839 postsynaptic density membrane;GO:0045211 postsynaptic membrane",
        "go_biological_process": "GO:0007206 phospholipase C-activating G protein-coupled glutamate receptor signaling pathway;GO:0051966 regulation of synaptic transmission, glutamatergic;GO:0007216 G protein-coupled glutamate receptor signaling pathway;GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A2R9YJL7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R9YJM4-1",
        "uniprot_id": [
            {
                "id": "A0A2R9YJM4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R9YJM4",
                "type": "external"
            }
        ],
        "mass": 50452.0,
        "length": 438,
        "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1a",
        "gene_name": "pacsin1a",
        "organism": "Zebrafish",
        "refseq_name": "protein kinase C and casein kinase substrate in neurons protein 1a",
        "refseq_ac": [
            {
                "id": "NP_001315286",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315286",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pacsin1a; zgc:109968",
        "gene_names_refseq": "pacsin1a; zgc:109968",
        "protein_names_uniprotkb": "Protein kinase C and casein kinase substrate in neurons protein 1a",
        "protein_names_refseq": "protein kinase C and casein kinase substrate in neurons protein 1a",
        "tax_id": 7955,
        "disease": "Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289)",
        "pathway": " (dre:553559)",
        "pathway_count": 1,
        "publication_count": 6,
        "publication_id_list": "21530505;26469318;27189481;28252024;30683896;35616009",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588733.622972.1, SRR32588724.2328995.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001315286.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; PACSIN1 and EHD1 assemble membrane tubules from the developing intracellular cilium that attach to the plasma membrane, creating an extracellular membrane channel to the outside of the cell. Erratum:[Nat Commun. 2019 Feb 19;10(1):919. doi: 10.1038/s41467-019-08872-0. PMID: 30783093] Publication Status: Online-Only, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 2,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PA61",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005543 phospholipid binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0032587 ruffle membrane",
        "go_biological_process": "GO:0006897 endocytosis;GO:0030100 regulation of endocytosis;GO:0048812 neuron projection morphogenesis;GO:0007010 cytoskeleton organization;GO:1900006 positive regulation of dendrite development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "A0A2R9YJM4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A2R9YJN8-1",
        "uniprot_id": [
            {
                "id": "A0A2R9YJN8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A2R9YJN8",
                "type": "external"
            }
        ],
        "mass": 87948.0,
        "length": 791,
        "protein_name": "RNA helicase",
        "gene_name": "ddx21",
        "organism": "Zebrafish",
        "refseq_name": "nucleolar RNA helicase 2",
        "refseq_ac": [
            {
                "id": "NP_001120807",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120807",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ddx21; cb960; wu:fi30c07; wu:fi34d08",
        "gene_names_refseq": "cb960; ddx21; wu:fi30c07; wu:fi34d08",
        "protein_names_uniprotkb": "RNA helicase; 3.6.4.13",
        "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 21; nucleolar RNA helicase 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:799650);  (R-DRE-5250924);  (R-DRE-6791226)",
        "pathway_count": 3,
        "publication_count": 10,
        "publication_id_list": "24396069;25535281;26469318;27069811;29364875;33242567;34440868;34750583;35701400;39496611",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC160629.1, SRR26395015.602240.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476758, SAMEA4476796 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1, EH525400.1, DT075062.1, DT065140.1, EH437022.1, EB906270.1 and EH463012.1. On Nov 5, 2015 this sequence version replaced NP_001120807.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase (Pol) I and II: promotes ribosomal RNA (rRNA) processing and transcription from polymerase II (Pol II). Binds various RNAs, such as rRNAs, snoRNAs, 7SK and, at lower extent, mRNAs. In the nucleolus, localizes to rDNA locus, where it directly binds rRNAs and snoRNAs, and promotes rRNA transcription, processing and modification. Required for rRNA 2'-O-methylation, possibly by promoting the recruitment of late-acting snoRNAs SNORD56 and SNORD58 with pre-ribosomal complexes. In the nucleoplasm, binds 7SK RNA and is recruited to the promoters of Pol II-transcribed genes: acts by facilitating the release of P-TEFb from inhibitory 7SK snRNP in a manner that is dependent on its helicase activity, thereby promoting transcription of its target genes. Required to prevent R-loop-associated DNA damage and transcription-associated genomic instability., [UniProtKB, UniProtKB, UniProtKB]; The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function., [RefSeq, PubMed]",
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1NHL0",
        "ec_number_list": [
            {
                "id": "2.3.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-",
                "type": "external"
            },
            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
                "type": "external"
            },
            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
                "type": "external"
            },
            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
                "type": "external"
            },
            {
                "id": "5.6.2.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4",
                "type": "external"
            },
            {
                "id": "5.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3",
                "type": "external"
            },
            {
                "id": "3.6.4.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
                "type": "external"
            },
            {
                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
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            {
                "id": "2.3.1.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48",
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            },
            {
                "id": "2.3.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-",
                "type": "external"
            },
            {
                "id": "2.7.4.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3",
                "type": "external"
            },
            {
                "id": "7.6.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2",
                "type": "external"
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            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
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            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            },
            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
            },
            {
                "id": "3.6.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
                "type": "external"
            },
            {
                "id": "3.6.1.15",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15",
                "type": "external"
            },
            {
                "id": "3.6.4.10",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "5.6.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-",
                "type": "external"
            },
            {
                "id": "2.7.7.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6",
                "type": "external"
            },
            {
                "id": "2.7.1.78",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
                "type": "external"
            },
            {
                "id": "5.6.2.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5",
                "type": "external"
            },
            {
                "id": "2.3.1.57",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.57",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity;GO:0004386 helicase activity",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005829 cytosol",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006364 rRNA processing",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A2R9YJN8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N020-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N020_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N020",
                "type": "external"
            }
        ],
        "mass": 39831.0,
        "length": 354,
        "protein_name": "5.4.99.25; Pseudouridylate synthase TRUB2, mitochondrial",
        "gene_name": "trub2",
        "organism": "Zebrafish",
        "refseq_name": "pseudouridylate synthase TRUB2, mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_001002200",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002200",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "trub2; fc51e05; wu:fc51e05; zgc:91836",
        "gene_names_refseq": "fc51e05; trub2; wu:fc51e05; zgc:91836",
        "protein_names_uniprotkb": "5.4.99.25; Pseudouridylate synthase TRUB2, mitochondrial",
        "protein_names_refseq": "pseudouridylate synthase TRUB2, mitochondrial",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:431747)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "26469318",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH588883.1, BC074078.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH588883.1, EH452545.1, EH526480.1 and BM036809.1. On Oct 7, 2011 this sequence version replaced NP_001002200.1., [RefSeq]",
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        "reported_o_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0160148 tRNA pseudouridine(55) synthase activity",
        "go_cellular_component": "GO:0005759 mitochondrial matrix",
        "go_biological_process": "GO:0006396 RNA processing;GO:1990481 mRNA pseudouridine synthesis;GO:0070131 positive regulation of mitochondrial translation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0A8M1N020-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N062-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N062_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N062",
                "type": "external"
            }
        ],
        "mass": 16625.0,
        "length": 145,
        "protein_name": "DNA-directed RNA polymerase II subunit RPB4",
        "gene_name": "polr2d",
        "organism": "Zebrafish",
        "refseq_name": "DNA-directed RNA polymerase II subunit RPB4",
        "refseq_ac": [
            {
                "id": "NP_001002317",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002317",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "polr2d; rnap; wu:fa95b11; zgc:110435",
        "gene_names_refseq": "polr2d; rnap; wu:fa95b11; zgc:110435",
        "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB4; DNA-directed RNA polymerase II subunit D; DNA-directed RNA polymerase II subunit rpb4",
        "protein_names_refseq": "DNA-directed RNA polymerase II subunit 2d; DNA-directed RNA polymerase II subunit RPB4; polymerase (RNA) II (DNA directed) polypeptide D",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:436588)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "15256591;17492136;19201018;26156497;26469318;34950046;35278627;36846912;38097556;38710511",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH555518.1, EH441890.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH541343.1 and EH555518.1. On Apr 4, 2014 this sequence version replaced NP_001002317.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2D/RPB4 is part of a subcomplex with POLR2G/RPB7 that binds to a pocket formed by POLR2A/RPB1, POLR2B/RPB2 and POLR2F/RPABC2 at the base of the clamp element. The POLR2D/RPB4-POLR2G/RPB7 subcomplex seems to lock the clamp via POLR2G/RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The POLR2D/RPB4-POLR2G/RPB7 subcomplex binds single-stranded DNA and RNA., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000166 nucleotide binding;GO:0031369 translation initiation factor binding",
        "go_cellular_component": "GO:0005665 RNA polymerase II, core complex",
        "go_biological_process": "GO:0006367 transcription initiation at RNA polymerase II promoter",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A8M1N062-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N0E2-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N0E2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N0E2",
                "type": "external"
            }
        ],
        "mass": 35551.0,
        "length": 333,
        "protein_name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial",
        "gene_name": "decr1",
        "organism": "Zebrafish",
        "refseq_name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_001002444",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002444",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "decr1; fe38b07; wu:fe38b07; zgc:92356",
        "gene_names_refseq": "decr1; fe38b07; wu:fe38b07; zgc:92356",
        "protein_names_uniprotkb": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial; 1.3.1.124; 2,4-dienoyl-CoA reductase [NADPH]",
        "protein_names_refseq": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:436717)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "26469318;27189481;28252024;31036921;32648304;36126741;40044042;8373170",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination        :: BC076027.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH504463.1, EH572714.1 and EH595644.1. On Oct 8, 2011 this sequence version replaced NP_001002444.1., [RefSeq]; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 1,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 1,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 1,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 1,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 0,
        "biomarker_type": "",
        "glycan_count": 1,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.3.1.124",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006635 fatty acid beta-oxidation",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A8M1N0E2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N0T3-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N0T3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N0T3",
                "type": "external"
            }
        ],
        "mass": 32348.0,
        "length": 287,
        "protein_name": "small monomeric GTPase",
        "gene_name": "rab40b",
        "organism": "Zebrafish",
        "refseq_name": "ras-related protein Rab-40B",
        "refseq_ac": [
            {
                "id": "NP_001002524",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002524",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rab40b; zgc:92926",
        "gene_names_refseq": "rab40b; zgc:92926",
        "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2",
        "protein_names_refseq": "ras-related protein Rab-40B",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 4,
        "publication_id_list": "19409617;22581972;28396820;38196136",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC076375.1, EL651216.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076375.1. On Oct 4, 2011 this sequence version replaced NP_001002524.1. Sequence Note: This RefSeq record was created from a transcript of a different strain than the reference genome strain because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
            },
            {
                "id": "3.6.5.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3",
                "type": "external"
            },
            {
                "id": "3.6.5.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5",
                "type": "external"
            },
            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            },
            {
                "id": "3.6.5.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity",
        "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0008021 synaptic vesicle",
        "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016567 protein ubiquitination;GO:0006887 exocytosis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A8M1N0T3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N0V4-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N0V4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N0V4",
                "type": "external"
            }
        ],
        "mass": 32763.0,
        "length": 297,
        "protein_name": "Ribonuclease H1",
        "gene_name": "rnaseh1",
        "organism": "Zebrafish",
        "refseq_name": "ribonuclease H1 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001002659",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002659",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rnaseh1; zgc:91971",
        "gene_names_refseq": "rnaseh1; zgc:91971",
        "protein_names_uniprotkb": "Ribonuclease H1; 3.1.26.4; RNase H1",
        "protein_names_refseq": "ribonuclease H1 isoform 1",
        "tax_id": 7955,
        "disease": "autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (Disease Ontology:DOID:0111515)",
        "pathway": " (dre:436932)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "26469318;33214638;38974143;39217460",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC076457.1, EG580972.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH542009.1 and BC076457.1. On Oct 25, 2013 this sequence version replaced NP_001002659.1. Transcript Variant: This variant (1) encodes the longer isoform (1)., [RefSeq]; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003676 nucleic acid binding;GO:0004523 RNA-DNA hybrid ribonuclease activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0043137 DNA replication, removal of RNA primer",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0A8M1N0V4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1N0Y4-1",
        "uniprot_id": [
            {
                "id": "A0A8M1N0Y4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1N0Y4",
                "type": "external"
            }
        ],
        "mass": 23566.0,
        "length": 199,
        "protein_name": "Regulator of G-protein signaling 2",
        "gene_name": "rgs2",
        "organism": "Zebrafish",
        "refseq_name": "regulator of G-protein signaling 2",
        "refseq_ac": [
            {
                "id": "NP_001002662",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002662",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rgs2; fa96c08; wu:fa96c08; wu:fj08f11; zgc:91965",
        "gene_names_refseq": "fa96c08; rgs2; wu:fa96c08; wu:fj08f11; zgc:91965",
        "protein_names_uniprotkb": "Regulator of G-protein signaling 2",
        "protein_names_refseq": "regulator of G-protein signaling 2",
        "tax_id": 7955,
        "disease": "glomerulosclerosis (Disease Ontology:DOID:0050851); hypertension (Disease Ontology:DOID:10763); opioid abuse (Disease Ontology:DOID:11206); bladder disease (Disease Ontology:DOID:365); liver cirrhosis (Disease Ontology:DOID:5082); female stress incontinence (Disease Ontology:DOID:724)",
        "pathway": " (dre:436935)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "27979767;28111234;30728369;30826544;31680844;31921316;33168193;33560393;34400286;37443828",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC076456.1, EH553343.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505392 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1 and BC076456.1. On or before Jan 23, 2009 this sequence version replaced XP_001923584.1, NP_001002662.1., [RefSeq]; This study reveals a unique regulatory mechanism, the Rgs2-Ppard-Sox10 signaling cascade, and defines a key molecular regulator, Rgs2, in neural crest development., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 6,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005096 GTPase activator activity",
        "go_cellular_component": "GO:0009898 cytoplasmic side of plasma membrane",
        "go_biological_process": "GO:0090301 negative regulation of neural crest formation;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0014032 neural crest cell development",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0A8M1N0Y4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    }
]
